diff options
Diffstat (limited to 'uploader')
166 files changed, 11684 insertions, 2266 deletions
diff --git a/uploader/__init__.py b/uploader/__init__.py index 2d731af..8b49ad5 100644 --- a/uploader/__init__.py +++ b/uploader/__init__.py @@ -3,20 +3,33 @@ import os import sys import logging from pathlib import Path +from typing import Optional from flask import Flask, request + +from cachelib import FileSystemCache + +from gn_libs import jobs as gnlibs_jobs + from flask_session import Session + from uploader.oauth2.client import user_logged_in, authserver_authorise_uri -from .entry import entrybp -from .upload import upload -from .parse import parsebp -from .samples import samples +from . import session from .base_routes import base -from .dbinsert import dbinsertbp +from .files.views import files +from .species import speciesbp +from .publications import pubbp from .oauth2.views import oauth2 +from .expression_data import exprdatabp from .errors import register_error_handlers +from .background_jobs import background_jobs_bp + +logging.basicConfig( + format=("%(asctime)s — %(filename)s:%(lineno)s — %(levelname)s " + "(%(thread)d:%(threadName)s): %(message)s") +) def override_settings_with_envvars( app: Flask, ignore: tuple[str, ...]=tuple()) -> None: @@ -51,10 +64,30 @@ def setup_logging(app: Flask) -> Flask: "SERVER_SOFTWARE", "").split('/') return __log_gunicorn__(app) if bool(software) else __log_dev__(app) +def setup_modules_logging(app_logger): + """Setup module-level loggers to the same log-level as the application.""" + loglevel = logging.getLevelName(app_logger.getEffectiveLevel()) + + def __setup__(logger_name): + _logger = logging.getLogger(logger_name) + _logger.setLevel(loglevel) + + __setup__("uploader.publications.models") + __setup__("uploader.publications.datatables") + + +def create_app(config: Optional[dict] = None): + """The application factory. + + config: dict + Useful to override settings in the settings files and environment + especially in environments such as testing.""" + if config is None: + config = {} -def create_app(): - """The application factory""" app = Flask(__name__) + + ### BEGIN: Application configuration app.config.from_pyfile( Path(__file__).parent.joinpath("default_settings.py")) if "UPLOADER_CONF" in os.environ: @@ -69,8 +102,16 @@ def create_app(): if secretsfile.exists(): # Silently ignore secrets if the file does not exist. app.config.from_pyfile(secretsfile) + app.config.update(config) # Override everything with passed in config + ### END: Application configuration + + app.config["SESSION_CACHELIB"] = FileSystemCache( + cache_dir=Path(app.config["SESSION_FILESYSTEM_CACHE_PATH"]).absolute(), + threshold=int(app.config["SESSION_FILESYSTEM_CACHE_THRESHOLD"]), + default_timeout=int(app.config["SESSION_FILESYSTEM_CACHE_TIMEOUT"])) setup_logging(app) + setup_modules_logging(app.logger) # setup jinja2 symbols app.add_template_global(lambda : request.url, name="request_url") @@ -78,17 +119,18 @@ def create_app(): app.add_template_global(lambda: app.config["GN2_SERVER_URL"], name="gn2server_uri") app.add_template_global(user_logged_in) + app.add_template_global(lambda : session.user_details()["email"], name="user_email") Session(app) # setup blueprints app.register_blueprint(base, url_prefix="/") - app.register_blueprint(entrybp, url_prefix="/") - app.register_blueprint(parsebp, url_prefix="/parse") + app.register_blueprint(files, url_prefix="/files") app.register_blueprint(oauth2, url_prefix="/oauth2") - app.register_blueprint(upload, url_prefix="/upload") - app.register_blueprint(dbinsertbp, url_prefix="/dbinsert") - app.register_blueprint(samples, url_prefix="/samples") + app.register_blueprint(speciesbp, url_prefix="/species") + app.register_blueprint(pubbp, url_prefix="/publications") + app.register_blueprint(background_jobs_bp, url_prefix="/background-jobs/") register_error_handlers(app) + gnlibs_jobs.init_app(app) return app diff --git a/uploader/authorisation.py b/uploader/authorisation.py index 8ab83f8..3cf3585 100644 --- a/uploader/authorisation.py +++ b/uploader/authorisation.py @@ -1,21 +1,66 @@ """Authorisation utilities.""" +import logging from functools import wraps +from typing import Callable from flask import flash, redirect +from pymonad.either import Left, Right, Either +from authlib.jose import KeySet, JsonWebToken +from authlib.jose.errors import BadSignatureError from uploader import session +from uploader.oauth2.client import auth_server_jwks def require_login(function): """Check that the user is logged in before executing `func`.""" @wraps(function) def __is_session_valid__(*args, **kwargs): """Check that the user is logged in and their token is valid.""" - def __clear_session__(_no_token): - session.clear_session_info() - flash("You need to be logged in.", "alert-danger") + def __alert_needs_sign_in__(_no_token): + flash("You need to be signed in.", "alert alert-danger big-alert") return redirect("/") return session.user_token().either( - __clear_session__, + __alert_needs_sign_in__, lambda token: function(*args, **kwargs)) return __is_session_valid__ + + +def __validate_token__(jwks: KeySet, token: dict) -> Either: + """Check that a token is signed by a key from the authorisation server.""" + for key in jwks.keys: + try: + # Fixes CVE-2016-10555. See + # https://docs.authlib.org/en/latest/jose/jwt.html + jwt = JsonWebToken(["RS256"]) + jwt.decode(token["access_token"], key) + return Right(token) + except BadSignatureError: + pass + + return Left({"token": token}) + + +def require_token(func: Callable) -> Callable: + """ + Wrap functions that require the user be authorised to perform the operations + that the functions in question provide. + """ + def __invalid_token__(_whatever): + logging.debug("==========> Failure log: %s", _whatever) + raise Exception(# pylint: disable=[broad-exception-raised] + "You attempted to access a feature of the system that requires " + "authorisation. Unfortunately, we could not verify you have the " + "appropriate authorisation to perform the action you requested. " + "You might need to log in, or if you already are logged in, you " + "need to log out, then log back in to get a newer token/session.") + @wraps(func) + def __wrapper__(*args, **kwargs): + return session.user_token().then(lambda tok: { + "jwks": auth_server_jwks(), + "token": tok + }).then(lambda vals: __validate_token__(**vals)).either( + __invalid_token__, + lambda tok: func(*args, **{**kwargs, "token": tok})) + + return __wrapper__ diff --git a/uploader/background_jobs.py b/uploader/background_jobs.py new file mode 100644 index 0000000..dc9f837 --- /dev/null +++ b/uploader/background_jobs.py @@ -0,0 +1,119 @@ +"""Generic views and utilities to handle background jobs.""" +import uuid +import importlib +from typing import Callable +from functools import partial + +from flask import ( + url_for, + redirect, + Response, + Blueprint, + render_template, + current_app as app) + +from gn_libs import jobs +from gn_libs import sqlite3 +from gn_libs.jobs.jobs import JobNotFound + +from uploader.authorisation import require_login + +background_jobs_bp = Blueprint("background-jobs", __name__) +HandlerType = Callable[[dict], Response] + + +def __default_error_handler__(job: dict) -> Response: + return redirect(url_for("background-jobs.job_error", job_id=job["job_id"])) + +def register_handlers( + job_type: str, + success_handler: HandlerType, + # pylint: disable=[redefined-outer-name] + error_handler: HandlerType = __default_error_handler__ + # pylint: disable=[redefined-outer-name] +) -> str: + """Register success and error handlers for each job type.""" + if not bool(app.config.get("background-jobs")): + app.config["background-jobs"] = {} + + if not bool(app.config["background-jobs"].get(job_type)): + app.config["background-jobs"][job_type] = { + "success": success_handler, + "error": error_handler + } + + return job_type + + +def register_job_handlers(job: str): + """Related to register handlers above.""" + def __load_handler__(absolute_function_path): + _parts = absolute_function_path.split(".") + app.logger.debug("THE PARTS ARE: %s", _parts) + assert len(_parts) > 1, f"Invalid path: {absolute_function_path}" + module = importlib.import_module(f".{_parts[-2]}", + package=".".join(_parts[0:-2])) + return getattr(module, _parts[-1]) + + metadata = job["metadata"] + if metadata["success_handler"]: + _success_handler = __load_handler__(metadata["success_handler"]) + try: + _error_handler = __load_handler__(metadata["error_handler"]) + except Exception as _exc:# pylint: disable=[broad-exception-caught] + _error_handler = __default_error_handler__ + register_handlers( + metadata["job-type"], _success_handler, _error_handler) + + +def handler(job: dict, handler_type: str) -> HandlerType: + """Fetch a handler for the job.""" + _job_type = job["metadata"]["job-type"] + _handler = app.config.get( + "background-jobs", {} + ).get( + _job_type, {} + ).get(handler_type) + if bool(_handler): + return _handler(job) + raise Exception(# pylint: disable=[broad-exception-raised] + f"No '{handler_type}' handler registered for job type: {_job_type}") + + +error_handler = partial(handler, handler_type="error") +success_handler = partial(handler, handler_type="success") + + +@background_jobs_bp.route("/status/<uuid:job_id>") +@require_login +def job_status(job_id: uuid.UUID): + """View the job status.""" + with sqlite3.connection(app.config["ASYNCHRONOUS_JOBS_SQLITE_DB"]) as conn: + try: + job = jobs.job(conn, job_id, fulldetails=True) + status = job["metadata"]["status"] + + register_job_handlers(job) + if status == "error": + return error_handler(job) + + if status == "completed": + return success_handler(job) + + return render_template("jobs/job-status.html", job=job) + except JobNotFound as _jnf: + return render_template( + "jobs/job-not-found.html", + job_id=job_id) + + +@background_jobs_bp.route("/error/<uuid:job_id>") +@require_login +def job_error(job_id: uuid.UUID): + """Handle job errors in a generic manner.""" + with sqlite3.connection(app.config["ASYNCHRONOUS_JOBS_SQLITE_DB"]) as conn: + try: + job = jobs.job(conn, job_id, fulldetails=True) + return render_template("jobs/job-error.html", job=job) + except JobNotFound as _jnf: + return render_template("jobs/job-not-found.html", job_id=job_id) diff --git a/uploader/base_routes.py b/uploader/base_routes.py index 9daf439..74a3b90 100644 --- a/uploader/base_routes.py +++ b/uploader/base_routes.py @@ -1,8 +1,32 @@ """Basic routes required for all pages""" import os -from flask import Blueprint, send_from_directory +from urllib.parse import urljoin + +from flask import (Blueprint, + current_app as app, + send_from_directory) + +from uploader.ui import make_template_renderer +from uploader.oauth2.client import user_logged_in base = Blueprint("base", __name__) +render_template = make_template_renderer("home") + + +@base.route("/favicon.ico", methods=["GET"]) +def favicon(): + """Return the favicon.""" + return send_from_directory(os.path.join(app.root_path, "static"), + "images/CITGLogo.png", + mimetype="image/png") + + +@base.route("/", methods=["GET"]) +def index(): + """Load the landing page""" + return render_template("index.html" if user_logged_in() else "login.html", + gn2server_intro=urljoin(app.config["GN2_SERVER_URL"], + "/intro")) def appenv(): """Get app's guix environment path.""" @@ -11,8 +35,8 @@ def appenv(): @base.route("/bootstrap/<path:filename>") def bootstrap(filename): """Fetch bootstrap files.""" - return send_from_directory( - appenv(), f"share/genenetwork2/javascript/bootstrap/{filename}") + return send_from_directory(appenv(), f"share/web/bootstrap/{filename}") + @base.route("/jquery/<path:filename>") @@ -22,6 +46,19 @@ def jquery(filename): appenv(), f"share/genenetwork2/javascript/jquery/{filename}") +@base.route("/datatables/<path:filename>") +def datatables(filename): + """Fetch DataTables files.""" + return send_from_directory( + appenv(), f"share/genenetwork2/javascript/DataTables/{filename}") + +@base.route("/datatables-extensions/<path:filename>") +def datatables_extensions(filename): + """Fetch DataTables files.""" + return send_from_directory( + appenv(), f"share/genenetwork2/javascript/DataTablesExtensions/{filename}") + + @base.route("/node-modules/<path:filename>") def node_modules(filename): """Fetch node-js modules.""" diff --git a/uploader/check_connections.py b/uploader/check_connections.py index 2561e55..c9b9aa3 100644 --- a/uploader/check_connections.py +++ b/uploader/check_connections.py @@ -4,8 +4,7 @@ import traceback import redis import MySQLdb - -from uploader.db_utils import database_connection +from gn_libs.mysqldb import database_connection def check_redis(uri: str): "Check the redis connection" diff --git a/uploader/datautils.py b/uploader/datautils.py new file mode 100644 index 0000000..46a55c4 --- /dev/null +++ b/uploader/datautils.py @@ -0,0 +1,38 @@ +"""Generic data utilities: Rename module.""" +import math +from functools import reduce +from typing import Union, Sequence + +def enumerate_sequence(seq: Sequence[dict], start:int = 1) -> Sequence[dict]: + """Enumerate sequence beginning at 1""" + return tuple({**item, "sequence_number": seqno} + for seqno, item in enumerate(seq, start=start)) + + +def order_by_family(items: tuple[dict, ...], + family_key: str = "Family", + order_key: str = "FamilyOrderId") -> list: + """Order the populations by their families.""" + def __family_order__(item): + orderval = item[order_key] + return math.inf if orderval is None else orderval + + def __order__(ordered, current): + _key = (__family_order__(current), current[family_key]) + return { + **ordered, + _key: ordered.get(_key, tuple()) + (current,) + } + + return sorted(tuple(reduce(__order__, items, {}).items()), + key=lambda item: item[0][0]) + + +def safe_int(val: Union[str, int, float]) -> int: + """ + Convert val into an integer: if val cannot be converted, return a zero. + """ + try: + return int(val) + except ValueError: + return 0 diff --git a/uploader/db/__init__.py b/uploader/db/__init__.py index 36e93e8..d2b1d9d 100644 --- a/uploader/db/__init__.py +++ b/uploader/db/__init__.py @@ -1,8 +1,2 @@ """Database functions""" -from .species import species, species_by_id -from .populations import ( - save_population, - population_by_id, - populations_by_species, - population_by_species_and_id) from .datasets import geno_datasets_by_species_and_population diff --git a/uploader/db/platforms.py b/uploader/db/platforms.py deleted file mode 100644 index cb527a7..0000000 --- a/uploader/db/platforms.py +++ /dev/null @@ -1,25 +0,0 @@ -"""Handle db interactions for platforms.""" -from typing import Optional - -import MySQLdb as mdb -from MySQLdb.cursors import DictCursor - -def platforms_by_species( - conn: mdb.Connection, speciesid: int) -> tuple[dict, ...]: - """Retrieve platforms by the species""" - with conn.cursor(cursorclass=DictCursor) as cursor: - cursor.execute("SELECT * FROM GeneChip WHERE SpeciesId=%s " - "ORDER BY GeneChipName ASC", - (speciesid,)) - return tuple(dict(row) for row in cursor.fetchall()) - -def platform_by_id(conn: mdb.Connection, platformid: int) -> Optional[dict]: - """Retrieve a platform by its ID""" - with conn.cursor(cursorclass=DictCursor) as cursor: - cursor.execute("SELECT * FROM GeneChip WHERE Id=%s", - (platformid,)) - result = cursor.fetchone() - if bool(result): - return dict(result) - - return None diff --git a/uploader/db/populations.py b/uploader/db/populations.py deleted file mode 100644 index 4485e52..0000000 --- a/uploader/db/populations.py +++ /dev/null @@ -1,54 +0,0 @@ -"""Functions for accessing the database relating to species populations.""" -import MySQLdb as mdb -from MySQLdb.cursors import DictCursor - -def population_by_id(conn: mdb.Connection, population_id) -> dict: - """Get the grouping/population by id.""" - with conn.cursor(cursorclass=DictCursor) as cursor: - cursor.execute("SELECT * FROM InbredSet WHERE InbredSetId=%s", - (population_id,)) - return cursor.fetchone() - -def population_by_species_and_id( - conn: mdb.Connection, species_id, population_id) -> dict: - """Retrieve a population by its identifier and species.""" - with conn.cursor(cursorclass=DictCursor) as cursor: - cursor.execute("SELECT * FROM InbredSet WHERE SpeciesId=%s AND Id=%s", - (species_id, population_id)) - return cursor.fetchone() - -def populations_by_species(conn: mdb.Connection, speciesid) -> tuple: - "Retrieve group (InbredSet) information from the database." - with conn.cursor(cursorclass=DictCursor) as cursor: - query = "SELECT * FROM InbredSet WHERE SpeciesId=%s" - cursor.execute(query, (speciesid,)) - return tuple(cursor.fetchall()) - - return tuple() - -def save_population(conn: mdb.Connection, population_details: dict) -> dict: - """Save the population details to the db.""" - with conn.cursor(cursorclass=DictCursor) as cursor: - cursor.execute( - "INSERT INTO InbredSet(" - "InbredSetId, InbredSetName, Name, SpeciesId, FullName, " - "MenuOrderId, Description" - ") " - "VALUES (" - "%(InbredSetId)s, %(InbredSetName)s, %(Name)s, %(SpeciesId)s, " - "%(FullName)s, %(MenuOrderId)s, %(Description)s" - ")", - { - "MenuOrderId": 0, - "InbredSetId": 0, - **population_details - }) - new_id = cursor.lastrowid - cursor.execute("UPDATE InbredSet SET InbredSetId=%s WHERE Id=%s", - (new_id, new_id)) - return { - **population_details, - "Id": new_id, - "InbredSetId": new_id, - "population_id": new_id - } diff --git a/uploader/db/species.py b/uploader/db/species.py deleted file mode 100644 index 653e59b..0000000 --- a/uploader/db/species.py +++ /dev/null @@ -1,22 +0,0 @@ -"""Database functions for species.""" -import MySQLdb as mdb -from MySQLdb.cursors import DictCursor - -def species(conn: mdb.Connection) -> tuple: - "Retrieve the species from the database." - with conn.cursor(cursorclass=DictCursor) as cursor: - cursor.execute( - "SELECT SpeciesId, SpeciesName, LOWER(Name) AS Name, MenuName, " - "FullName FROM Species") - return tuple(cursor.fetchall()) - - return tuple() - -def species_by_id(conn: mdb.Connection, speciesid) -> dict: - "Retrieve the species from the database by id." - with conn.cursor(cursorclass=DictCursor) as cursor: - cursor.execute( - "SELECT SpeciesId, SpeciesName, LOWER(Name) AS Name, MenuName, " - "FullName FROM Species WHERE SpeciesId=%s", - (speciesid,)) - return cursor.fetchone() diff --git a/uploader/db_utils.py b/uploader/db_utils.py index 5b79762..d9d521e 100644 --- a/uploader/db_utils.py +++ b/uploader/db_utils.py @@ -1,43 +1,18 @@ """module contains all db related stuff""" -import logging -import traceback -import contextlib -from urllib.parse import urlparse -from typing import Any, Tuple, Iterator, Callable +from typing import Any, Callable import MySQLdb as mdb from redis import Redis from flask import current_app as app +from gn_libs.mysqldb import database_connection -def parse_db_url(db_url) -> Tuple: - """ - Parse SQL_URI configuration variable. - """ - parsed_db = urlparse(db_url) - return (parsed_db.hostname, parsed_db.username, - parsed_db.password, parsed_db.path[1:], parsed_db.port) - - -@contextlib.contextmanager -def database_connection(db_url: str) -> Iterator[mdb.Connection]: - """function to create db connector""" - host, user, passwd, db_name, db_port = parse_db_url(db_url) - connection = mdb.connect( - host, user, passwd, db_name, port=(db_port or 3306)) - try: - yield connection - connection.commit() - except mdb.Error as _mdb_err: - logging.error(traceback.format_exc()) - connection.rollback() - finally: - connection.close() def with_db_connection(func: Callable[[mdb.Connection], Any]) -> Any: """Call `func` with a MySQDdb database connection.""" with database_connection(app.config["SQL_URI"]) as conn: return func(conn) + def with_redis_connection(func: Callable[[Redis], Any]) -> Any: """Call `func` with a redis connection.""" redisuri = app.config["REDIS_URL"] diff --git a/uploader/default_settings.py b/uploader/default_settings.py index 26fe665..1136ff8 100644 --- a/uploader/default_settings.py +++ b/uploader/default_settings.py @@ -2,22 +2,31 @@ The default configuration file. The values here should be overridden in the actual configuration file used for the production and staging systems. """ +import hashlib -import os - -LOG_LEVEL = os.getenv("LOG_LEVEL", "WARNING") +LOG_LEVEL = "WARNING" SECRET_KEY = b"<Please! Please! Please! Change This!>" UPLOAD_FOLDER = "/tmp/qc_app_files" +TEMPORARY_DIRECTORY = "/tmp/gn-uploader-tmpdir" REDIS_URL = "redis://" JOBS_TTL_SECONDS = 1209600 # 14 days -GNQC_REDIS_PREFIX="GNQC" +GNQC_REDIS_PREFIX="gn-uploader" SQL_URI = "" GN2_SERVER_URL = "https://genenetwork.org/" -SESSION_TYPE = "redis" SESSION_PERMANENT = True SESSION_USE_SIGNER = True +SESSION_TYPE = "cachelib" +## --- Settings for CacheLib session type --- ## +## --- These are on flask-session config variables --- ## +## --- https://cachelib.readthedocs.io/en/stable/file/ --- ## +SESSION_FILESYSTEM_CACHE_PATH = "./flask_session" +SESSION_FILESYSTEM_CACHE_THRESHOLD = 500 +SESSION_FILESYSTEM_CACHE_TIMEOUT = 300 +SESSION_FILESYSTEM_CACHE_MODE = 0o600 +SESSION_FILESYSTEM_CACHE_HASH_METHOD = hashlib.md5 +## --- END: Settings for CacheLib session type --- ## JWKS_ROTATION_AGE_DAYS = 7 # Days (from creation) to keep a JWK in use. JWKS_DELETION_AGE_DAYS = 14 # Days (from creation) to keep a JWK around before deleting it. diff --git a/uploader/entry.py b/uploader/entry.py deleted file mode 100644 index 82034ed..0000000 --- a/uploader/entry.py +++ /dev/null @@ -1,131 +0,0 @@ -"""Entry-point module""" -import os -import mimetypes -from typing import Tuple -from zipfile import ZipFile, is_zipfile - -from werkzeug.utils import secure_filename -from flask import ( - flash, - request, - url_for, - redirect, - Blueprint, - render_template, - current_app as app, - send_from_directory) - -from uploader.db import species -from uploader.authorisation import require_login -from uploader.db_utils import with_db_connection -from uploader.oauth2.client import user_logged_in - -entrybp = Blueprint("entry", __name__) - -@entrybp.route("/favicon.ico", methods=["GET"]) -def favicon(): - """Return the favicon.""" - return send_from_directory(os.path.join(app.root_path, "static"), - "images/CITGLogo.png", - mimetype="image/png") - - -def errors(rqst) -> Tuple[str, ...]: - """Return a tuple of the errors found in the request `rqst`. If no error is - found, then an empty tuple is returned.""" - def __filetype_error__(): - return ( - ("Invalid file type provided.",) - if rqst.form.get("filetype") not in ("average", "standard-error") - else tuple()) - - def __file_missing_error__(): - return ( - ("No file was uploaded.",) - if ("qc_text_file" not in rqst.files or - rqst.files["qc_text_file"].filename == "") - else tuple()) - - def __file_mimetype_error__(): - text_file = rqst.files["qc_text_file"] - return ( - ( - ("Invalid file! Expected a tab-separated-values file, or a zip " - "file of the a tab-separated-values file."),) - if text_file.mimetype not in ( - "text/plain", "text/tab-separated-values", - "application/zip") - else tuple()) - - return ( - __filetype_error__() + - (__file_missing_error__() or __file_mimetype_error__())) - -def zip_file_errors(filepath, upload_dir) -> Tuple[str, ...]: - """Check the uploaded zip file for errors.""" - zfile_errors: Tuple[str, ...] = tuple() - if is_zipfile(filepath): - with ZipFile(filepath, "r") as zfile: - infolist = zfile.infolist() - if len(infolist) != 1: - zfile_errors = zfile_errors + ( - ("Expected exactly one (1) member file within the uploaded zip " - f"file. Got {len(infolist)} member files."),) - if len(infolist) == 1 and infolist[0].is_dir(): - zfile_errors = zfile_errors + ( - ("Expected a member text file in the uploaded zip file. Got a " - "directory/folder."),) - - if len(infolist) == 1 and not infolist[0].is_dir(): - zfile.extract(infolist[0], path=upload_dir) - mime = mimetypes.guess_type(f"{upload_dir}/{infolist[0].filename}") - if mime[0] != "text/tab-separated-values": - zfile_errors = zfile_errors + ( - ("Expected the member text file in the uploaded zip file to" - " be a tab-separated file."),) - - return zfile_errors - -@entrybp.route("/", methods=["GET"]) -def index(): - """Load the landing page""" - return render_template("index.html" if user_logged_in() else "login.html") - -@entrybp.route("/upload", methods=["GET", "POST"]) -@require_login -def upload_file(): - """Enables uploading the files""" - if request.method == "GET": - return render_template( - "select_species.html", species=with_db_connection(species)) - - upload_dir = app.config["UPLOAD_FOLDER"] - request_errors = errors(request) - if request_errors: - for error in request_errors: - flash(error, "alert-danger error-expr-data") - return redirect(url_for("entry.upload_file")) - - filename = secure_filename(request.files["qc_text_file"].filename) - if not os.path.exists(upload_dir): - os.mkdir(upload_dir) - - filepath = os.path.join(upload_dir, filename) - request.files["qc_text_file"].save(os.path.join(upload_dir, filename)) - - zip_errors = zip_file_errors(filepath, upload_dir) - if zip_errors: - for error in zip_errors: - flash(error, "alert-danger error-expr-data") - return redirect(url_for("entry.upload_file")) - - return redirect(url_for("parse.parse", - speciesid=request.form["speciesid"], - filename=filename, - filetype=request.form["filetype"])) - -@entrybp.route("/data-review", methods=["GET"]) -@require_login -def data_review(): - """Provide some help on data expectations to the user.""" - return render_template("data_review.html") diff --git a/uploader/expression_data/__init__.py b/uploader/expression_data/__init__.py new file mode 100644 index 0000000..fc8bd41 --- /dev/null +++ b/uploader/expression_data/__init__.py @@ -0,0 +1,2 @@ +"""Package handling upload of files.""" +from .views import exprdatabp diff --git a/uploader/dbinsert.py b/uploader/expression_data/dbinsert.py index 559dc5e..6d8ce80 100644 --- a/uploader/dbinsert.py +++ b/uploader/expression_data/dbinsert.py @@ -7,15 +7,17 @@ from datetime import datetime from redis import Redis from MySQLdb.cursors import DictCursor +from gn_libs.mysqldb import database_connection from flask import ( flash, request, url_for, Blueprint, redirect, render_template, current_app as app) +from uploader import jobs from uploader.authorisation import require_login -from uploader.db_utils import with_db_connection, database_connection -from uploader.db import species, species_by_id, populations_by_species - -from . import jobs +from uploader.db_utils import with_db_connection +from uploader.population.models import populations_by_species +from uploader.species.models import all_species, species_by_id +from uploader.platforms.models import platform_by_species_and_id dbinsertbp = Blueprint("dbinsert", __name__) @@ -48,14 +50,6 @@ def genechips(): return {} -def platform_by_id(genechipid:int) -> Union[dict, None]: - "Retrieve the gene platform by id" - with database_connection(app.config["SQL_URI"]) as conn: - with conn.cursor(cursorclass=DictCursor) as cursor: - cursor.execute( - "SELECT * FROM GeneChip WHERE GeneChipId=%s", - (genechipid,)) - return cursor.fetchone() def studies_by_species_and_platform(speciesid:int, genechipid:int) -> tuple: "Retrieve the studies by the related species and gene platform" @@ -107,7 +101,7 @@ def select_platform(): return render_template( "select_platform.html", filename=filename, filetype=job["filetype"], totallines=int(job["currentline"]), - default_species=default_species, species=species(conn), + default_species=default_species, species=all_species(conn), genechips=gchips[default_species], genechips_data=json.dumps(gchips)) return render_error(f"File '{filename}' no longer exists.") @@ -326,37 +320,38 @@ def selected_keys(original: dict, keys: tuple) -> dict: @require_login def final_confirmation(): "Preview the data before triggering entry into the database" - form = request.form - try: - assert form.get("filename"), "filename" - assert form.get("filetype"), "filetype" - assert form.get("species"), "species" - assert form.get("genechipid"), "platform" - assert form.get("studyid"), "study" - assert form.get("datasetid"), "dataset" - - speciesid = form["species"] - genechipid = form["genechipid"] - studyid = form["studyid"] - datasetid=form["datasetid"] - return render_template( - "final_confirmation.html", filename=form["filename"], - filetype=form["filetype"], totallines=form["totallines"], - species=speciesid, genechipid=genechipid, studyid=studyid, - datasetid=datasetid, the_species=selected_keys( - with_db_connection(lambda conn: species_by_id(conn, speciesid)), - ("SpeciesName", "Name", "MenuName")), - platform=selected_keys( - platform_by_id(genechipid), - ("GeneChipName", "Name", "GeoPlatform", "Title", "GO_tree_value")), - study=selected_keys( - study_by_id(studyid), ("Name", "FullName", "ShortName")), - dataset=selected_keys( - dataset_by_id(datasetid), - ("AvgMethodName", "Name", "Name2", "FullName", "ShortName", - "DataScale"))) - except AssertionError as aserr: - return render_error(f"Missing data: {aserr.args[0]}") + with database_connection(app.config["SQL_URI"]) as conn: + form = request.form + try: + assert form.get("filename"), "filename" + assert form.get("filetype"), "filetype" + assert form.get("species"), "species" + assert form.get("genechipid"), "platform" + assert form.get("studyid"), "study" + assert form.get("datasetid"), "dataset" + + speciesid = form["species"] + genechipid = form["genechipid"] + studyid = form["studyid"] + datasetid=form["datasetid"] + return render_template( + "final_confirmation.html", filename=form["filename"], + filetype=form["filetype"], totallines=form["totallines"], + species=speciesid, genechipid=genechipid, studyid=studyid, + datasetid=datasetid, the_species=selected_keys( + with_db_connection(lambda conn: species_by_id(conn, speciesid)), + ("SpeciesName", "Name", "MenuName")), + platform=selected_keys( + platform_by_species_and_id(conn, speciesid, genechipid), + ("GeneChipName", "Name", "GeoPlatform", "Title", "GO_tree_value")), + study=selected_keys( + study_by_id(studyid), ("Name", "FullName", "ShortName")), + dataset=selected_keys( + dataset_by_id(datasetid), + ("AvgMethodName", "Name", "Name2", "FullName", "ShortName", + "DataScale"))) + except AssertionError as aserr: + return render_error(f"Missing data: {aserr.args[0]}") @dbinsertbp.route("/insert-data", methods=["POST"]) @require_login diff --git a/uploader/expression_data/views.py b/uploader/expression_data/views.py new file mode 100644 index 0000000..7629f3e --- /dev/null +++ b/uploader/expression_data/views.py @@ -0,0 +1,385 @@ +"""Views for expression data""" +import os +import uuid +import mimetypes +from typing import Tuple +from zipfile import ZipFile, is_zipfile + +import jsonpickle +from redis import Redis +from werkzeug.utils import secure_filename +from gn_libs.mysqldb import database_connection +from flask import (flash, + request, + url_for, + redirect, + Blueprint, + current_app as app) + +from quality_control.errors import InvalidValue, DuplicateHeading + +from uploader import jobs +from uploader.datautils import order_by_family +from uploader.ui import make_template_renderer +from uploader.authorisation import require_login +from uploader.db_utils import with_db_connection +from uploader.species.models import all_species, species_by_id +from uploader.population.models import (populations_by_species, + population_by_species_and_id) + +exprdatabp = Blueprint("expression-data", __name__) +render_template = make_template_renderer("expression-data") + +def isinvalidvalue(item): + """Check whether item is of type InvalidValue""" + return isinstance(item, InvalidValue) + + +def isduplicateheading(item): + """Check whether item is of type DuplicateHeading""" + return isinstance(item, DuplicateHeading) + + +def errors(rqst) -> Tuple[str, ...]: + """Return a tuple of the errors found in the request `rqst`. If no error is + found, then an empty tuple is returned.""" + def __filetype_error__(): + return ( + ("Invalid file type provided.",) + if rqst.form.get("filetype") not in ("average", "standard-error") + else tuple()) + + def __file_missing_error__(): + return ( + ("No file was uploaded.",) + if ("qc_text_file" not in rqst.files or + rqst.files["qc_text_file"].filename == "") + else tuple()) + + def __file_mimetype_error__(): + text_file = rqst.files["qc_text_file"] + return ( + ( + ("Invalid file! Expected a tab-separated-values file, or a zip " + "file of the a tab-separated-values file."),) + if text_file.mimetype not in ( + "text/plain", "text/tab-separated-values", + "application/zip") + else tuple()) + + return ( + __filetype_error__() + + (__file_missing_error__() or __file_mimetype_error__())) + + +def zip_file_errors(filepath, upload_dir) -> Tuple[str, ...]: + """Check the uploaded zip file for errors.""" + zfile_errors: Tuple[str, ...] = tuple() + if is_zipfile(filepath): + with ZipFile(filepath, "r") as zfile: + infolist = zfile.infolist() + if len(infolist) != 1: + zfile_errors = zfile_errors + ( + ("Expected exactly one (1) member file within the uploaded zip " + f"file. Got {len(infolist)} member files."),) + if len(infolist) == 1 and infolist[0].is_dir(): + zfile_errors = zfile_errors + ( + ("Expected a member text file in the uploaded zip file. Got a " + "directory/folder."),) + + if len(infolist) == 1 and not infolist[0].is_dir(): + zfile.extract(infolist[0], path=upload_dir) + mime = mimetypes.guess_type(f"{upload_dir}/{infolist[0].filename}") + if mime[0] != "text/tab-separated-values": + zfile_errors = zfile_errors + ( + ("Expected the member text file in the uploaded zip file to" + " be a tab-separated file."),) + + return zfile_errors + + +@exprdatabp.route("populations/expression-data", methods=["GET"]) +@require_login +def index(): + """Display the expression data index page.""" + with database_connection(app.config["SQL_URI"]) as conn: + if not bool(request.args.get("species_id")): + return render_template("expression-data/index.html", + species=order_by_family(all_species(conn)), + activelink="expression-data") + species = species_by_id(conn, request.args.get("species_id")) + if not bool(species): + flash("Could not find species selected!", "alert-danger") + return redirect(url_for("species.populations.expression-data.index")) + return redirect(url_for( + "species.populations.expression-data.select_population", + species_id=species["SpeciesId"])) + + +@exprdatabp.route("<int:species_id>/populations/expression-data/select-population", + methods=["GET"]) +@require_login +def select_population(species_id: int): + """Select the expression data's population.""" + with database_connection(app.config["SQL_URI"]) as conn: + species = species_by_id(conn, species_id) + if not bool(species): + flash("No such species!", "alert-danger") + return redirect(url_for("species.populations.expression-data.index")) + + if not bool(request.args.get("population_id")): + return render_template("expression-data/select-population.html", + species=species, + populations=order_by_family( + populations_by_species(conn, species_id), + order_key="FamilyOrder"), + activelink="expression-data") + + population = population_by_species_and_id( + conn, species_id, request.args.get("population_id")) + if not bool(population): + flash("No such population!", "alert-danger") + return redirect(url_for( + "species.populations.expression-data.select_population", + species_id=species_id)) + + return redirect(url_for("species.populations.expression-data.upload_file", + species_id=species_id, + population_id=population["Id"])) + + +@exprdatabp.route("<int:species_id>/populations/<int:population_id>/" + "expression-data/upload", + methods=["GET", "POST"]) +@require_login +def upload_file(species_id: int, population_id: int): + """Enables uploading the files""" + with database_connection(app.config["SQL_URI"]) as conn: + species = species_by_id(conn, species_id) + population = population_by_species_and_id(conn, species_id, population_id) + if request.method == "GET": + return render_template("expression-data/select-file.html", + species=species, + population=population) + + upload_dir = app.config["UPLOAD_FOLDER"] + request_errors = errors(request) + if request_errors: + for error in request_errors: + flash(error, "alert-danger error-expr-data") + return redirect(url_for("species.populations.expression-data.upload_file")) + + filename = secure_filename( + request.files["qc_text_file"].filename)# type: ignore[arg-type] + if not os.path.exists(upload_dir): + os.mkdir(upload_dir) + + filepath = os.path.join(upload_dir, filename) + request.files["qc_text_file"].save(os.path.join(upload_dir, filename)) + + zip_errors = zip_file_errors(filepath, upload_dir) + if zip_errors: + for error in zip_errors: + flash(error, "alert-danger error-expr-data") + return redirect(url_for("species.populations.expression-data.index.upload_file")) + + return redirect(url_for("species.populations.expression-data.parse_file", + species_id=species_id, + population_id=population_id, + filename=filename, + filetype=request.form["filetype"])) + + +@exprdatabp.route("/data-review", methods=["GET"]) +@require_login +def data_review(): + """Provide some help on data expectations to the user.""" + return render_template("expression-data/data-review.html") + + +@exprdatabp.route( + "<int:species_id>/populations/<int:population_id>/expression-data/parse", + methods=["GET"]) +@require_login +def parse_file(species_id: int, population_id: int): + """Trigger file parsing""" + _errors = False + filename = request.args.get("filename") + filetype = request.args.get("filetype") + + species = with_db_connection(lambda con: species_by_id(con, species_id)) + if not bool(species): + flash("No such species.", "alert-danger") + _errors = True + + if filename is None: + flash("No file provided", "alert-danger") + _errors = True + + if filetype is None: + flash("No filetype provided", "alert-danger") + _errors = True + + if filetype not in ("average", "standard-error"): + flash("Invalid filetype provided", "alert-danger") + _errors = True + + if filename: + filepath = os.path.join(app.config["UPLOAD_FOLDER"], filename) + if not os.path.exists(filepath): + flash("Selected file does not exist (any longer)", "alert-danger") + _errors = True + + if _errors: + return redirect(url_for("species.populations.expression-data.upload_file")) + + redisurl = app.config["REDIS_URL"] + with Redis.from_url(redisurl, decode_responses=True) as rconn: + job = jobs.launch_job( + jobs.build_file_verification_job( + rconn, app.config["SQL_URI"], redisurl, + species_id, filepath, filetype,# type: ignore[arg-type] + app.config["JOBS_TTL_SECONDS"]), + redisurl, + f"{app.config['UPLOAD_FOLDER']}/job_errors") + + return redirect(url_for("species.populations.expression-data.parse_status", + species_id=species_id, + population_id=population_id, + job_id=job["jobid"])) + + +@exprdatabp.route( + "<int:species_id>/populations/<int:population_id>/expression-data/parse/" + "status/<uuid:job_id>", + methods=["GET"]) +@require_login +def parse_status(species_id: int, population_id: int, job_id: str): + "Retrieve the status of the job" + with Redis.from_url(app.config["REDIS_URL"], decode_responses=True) as rconn: + try: + job = jobs.job(rconn, jobs.jobsnamespace(), job_id) + except jobs.JobNotFound as _exc: + return render_template("no_such_job.html", job_id=job_id), 400 + + error_filename = jobs.error_filename( + job_id, f"{app.config['UPLOAD_FOLDER']}/job_errors") + if os.path.exists(error_filename): + stat = os.stat(error_filename) + if stat.st_size > 0: + return redirect(url_for("parse.fail", job_id=job_id)) + + job_id = job["jobid"] + progress = float(job["percent"]) + status = job["status"] + filename = job.get("filename", "uploaded file") + _errors = jsonpickle.decode( + job.get("errors", jsonpickle.encode(tuple()))) + if status in ("success", "aborted"): + return redirect(url_for("species.populations.expression-data.results", + species_id=species_id, + population_id=population_id, + job_id=job_id)) + + if status == "parse-error": + return redirect(url_for("species.populations.expression-data.fail", job_id=job_id)) + + app.jinja_env.globals.update( + isinvalidvalue=isinvalidvalue, + isduplicateheading=isduplicateheading) + return render_template( + "expression-data/job-progress.html", + job_id = job_id, + job_status = status, + progress = progress, + message = job.get("message", ""), + job_name = f"Parsing '{filename}'", + errors=_errors, + species=with_db_connection( + lambda conn: species_by_id(conn, species_id)), + population=with_db_connection( + lambda conn: population_by_species_and_id( + conn, species_id, population_id))) + + +@exprdatabp.route( + "<int:species_id>/populations/<int:population_id>/expression-data/parse/" + "<uuid:job_id>/results", + methods=["GET"]) +@require_login +def results(species_id: int, population_id: int, job_id: uuid.UUID): + """Show results of parsing...""" + with Redis.from_url(app.config["REDIS_URL"], decode_responses=True) as rconn: + job = jobs.job(rconn, jobs.jobsnamespace(), job_id) + + if job: + filename = job["filename"] + _errors = jsonpickle.decode(job.get("errors", jsonpickle.encode(tuple()))) + app.jinja_env.globals.update( + isinvalidvalue=isinvalidvalue, + isduplicateheading=isduplicateheading) + return render_template( + "expression-data/parse-results.html", + errors=_errors, + job_name = f"Parsing '{filename}'", + user_aborted = job.get("user_aborted"), + job_id=job["jobid"], + species=with_db_connection( + lambda conn: species_by_id(conn, species_id)), + population=with_db_connection( + lambda conn: population_by_species_and_id( + conn, species_id, population_id))) + + return render_template("expression-data/no-such-job.html", job_id=job_id) + + +@exprdatabp.route( + "<int:species_id>/populations/<int:population_id>/expression-data/parse/" + "<uuid:job_id>/fail", + methods=["GET"]) +@require_login +def fail(species_id: int, population_id: int, job_id: str): + """Handle parsing failure""" + with Redis.from_url(app.config["REDIS_URL"], decode_responses=True) as rconn: + job = jobs.job(rconn, jobs.jobsnamespace(), job_id) + + if job: + error_filename = jobs.error_filename( + job_id, f"{app.config['UPLOAD_FOLDER']}/job_errors") + if os.path.exists(error_filename): + stat = os.stat(error_filename) + if stat.st_size > 0: + return render_template( + "worker_failure.html", job_id=job_id) + + return render_template("parse_failure.html", job=job) + + return render_template("expression-data/no-such-job.html", + **with_db_connection(lambda conn: { + "species_id": species_by_id(conn, species_id), + "population_id": population_by_species_and_id( + conn, species_id, population_id)}), + job_id=job_id) + + +@exprdatabp.route( + "<int:species_id>/populations/<int:population_id>/expression-data/parse/" + "abort", + methods=["POST"]) +@require_login +def abort(species_id: int, population_id: int): + """Handle user request to abort file processing""" + job_id = request.form["job_id"] + + with Redis.from_url(app.config["REDIS_URL"], decode_responses=True) as rconn: + job = jobs.job(rconn, jobs.jobsnamespace(), job_id) + + if job: + rconn.hset(name=jobs.job_key(jobs.jobsnamespace(), job_id), + key="user_aborted", + value=int(True)) + + return redirect(url_for("species.populations.expression-data.parse_status", + species_id=species_id, + population_id=population_id, + job_id=job_id)) diff --git a/uploader/files/__init__.py b/uploader/files/__init__.py new file mode 100644 index 0000000..53c3176 --- /dev/null +++ b/uploader/files/__init__.py @@ -0,0 +1,5 @@ +"""General files and chunks utilities.""" +from .chunks import chunked_binary_read +from .functions import (fullpath, + save_file, + sha256_digest_over_file) diff --git a/uploader/files/chunks.py b/uploader/files/chunks.py new file mode 100644 index 0000000..c4360b5 --- /dev/null +++ b/uploader/files/chunks.py @@ -0,0 +1,32 @@ +"""Functions dealing with chunking of files.""" +from pathlib import Path +from typing import Iterator + +from flask import current_app as app +from werkzeug.utils import secure_filename + + +def chunked_binary_read(filepath: Path, chunksize: int = 2048) -> Iterator: + """Read a file in binary mode in chunks.""" + with open(filepath, "rb") as inputfile: + while True: + data = inputfile.read(chunksize) + if data != b"": + yield data + continue + break + +def chunk_name(uploadfilename: str, chunkno: int) -> str: + """Generate chunk name from original filename and chunk number""" + if uploadfilename == "": + raise ValueError("Name cannot be empty!") + if chunkno < 1: + raise ValueError("Chunk number must be greater than zero") + return f"{secure_filename(uploadfilename)}_part_{chunkno:05d}" + + +def chunks_directory(uniqueidentifier: str) -> Path: + """Compute the directory where chunks are temporarily stored.""" + if uniqueidentifier == "": + raise ValueError("Unique identifier cannot be empty!") + return Path(app.config["UPLOAD_FOLDER"], f"tempdir_{uniqueidentifier}") diff --git a/uploader/files.py b/uploader/files/functions.py index b163612..7b9f06b 100644 --- a/uploader/files.py +++ b/uploader/files/functions.py @@ -2,17 +2,23 @@ import hashlib from pathlib import Path from datetime import datetime + from flask import current_app from werkzeug.utils import secure_filename from werkzeug.datastructures import FileStorage -def save_file(fileobj: FileStorage, upload_dir: Path) -> Path: +from .chunks import chunked_binary_read + +def save_file(fileobj: FileStorage, upload_dir: Path, hashed: bool = True) -> Path: """Save the uploaded file and return the path.""" assert bool(fileobj), "Invalid file object!" - hashed_name = hashlib.sha512( - f"{fileobj.filename}::{datetime.now().isoformat()}".encode("utf8") - ).hexdigest() + hashed_name = ( + hashlib.sha512( + f"{fileobj.filename}::{datetime.now().isoformat()}".encode("utf8") + ).hexdigest() + if hashed else + fileobj.filename) filename = Path(secure_filename(hashed_name)) # type: ignore[arg-type] if not upload_dir.exists(): upload_dir.mkdir() @@ -21,6 +27,16 @@ def save_file(fileobj: FileStorage, upload_dir: Path) -> Path: fileobj.save(filepath) return filepath + def fullpath(filename: str): """Get a file's full path. This makes use of `flask.current_app`.""" return Path(current_app.config["UPLOAD_FOLDER"], filename).absolute() + + +def sha256_digest_over_file(filepath: Path) -> str: + """Compute the sha256 digest over a file's contents.""" + filehash = hashlib.sha256() + for chunk in chunked_binary_read(filepath): + filehash.update(chunk) + + return filehash.hexdigest() diff --git a/uploader/files/views.py b/uploader/files/views.py new file mode 100644 index 0000000..29059c7 --- /dev/null +++ b/uploader/files/views.py @@ -0,0 +1,157 @@ +"""Module for generic files endpoints.""" +import time +import random +import traceback +from pathlib import Path + +from flask import request, jsonify, Blueprint, current_app as app + +from .chunks import chunk_name, chunks_directory + +files = Blueprint("files", __name__) + +def target_file(fileid: str) -> Path: + """Compute the full path for the target file.""" + return Path(app.config["UPLOAD_FOLDER"], fileid) + + +@files.route("/upload/resumable", methods=["GET"]) +def resumable_upload_get(): + """Used for checking whether **ALL** chunks have been uploaded.""" + fileid = request.args.get("resumableIdentifier", type=str) or "" + filename = request.args.get("resumableFilename", type=str) or "" + chunk = request.args.get("resumableChunkNumber", type=int) or 0 + if not(fileid or filename or chunk): + return jsonify({ + "message": "At least one required query parameter is missing.", + "error": "BadRequest", + "statuscode": 400 + }), 400 + + # If the complete target file exists, return 200 for all chunks. + _targetfile = target_file(fileid) + if _targetfile.exists(): + return jsonify({ + "uploaded-file": _targetfile.name, + "original-name": filename, + "chunk": chunk, + "message": "The complete file already exists.", + "statuscode": 200 + }), 200 + + if Path(chunks_directory(fileid), + chunk_name(filename, chunk)).exists(): + return jsonify({ + "chunk": chunk, + "message": f"Chunk {chunk} exists.", + "statuscode": 200 + }), 200 + + return jsonify({ + "message": f"Chunk {chunk} was not found.", + "error": "NotFound", + "statuscode": 404 + }), 404 + + +def __merge_chunks__(targetfile: Path, chunkpaths: tuple[Path, ...]) -> Path: + """Merge the chunks into a single file.""" + with open(targetfile, "ab") as _target: + for chunkfile in chunkpaths: + app.logger.error("Merging chunk: %s", chunkfile) + with open(chunkfile, "rb") as _chunkdata: + _target.write(_chunkdata.read()) + + chunkfile.unlink() # Don't use `missing_ok=True` — chunk MUST exist + # If chunk does't exist, it might indicate a race condition. Handle + # that instead. + return targetfile + + +@files.route("/upload/resumable", methods=["POST"]) +def resumable_upload_post(): + """Do the actual chunks upload here.""" + _totalchunks = request.form.get("resumableTotalChunks", type=int) or 0 + _chunk = request.form.get("resumableChunkNumber", default=1, type=int) + _uploadfilename = request.form.get( + "resumableFilename", default="", type=str) or "" + _fileid = request.form.get( + "resumableIdentifier", default="", type=str) or "" + _targetfile = target_file(_fileid) + + if _targetfile.exists(): + return jsonify({ + "uploaded-file": _targetfile.name, + "original-name": _uploadfilename, + "message": "File was uploaded successfully!", + "statuscode": 200 + }), 200 + + try: + chunks_directory(_fileid).mkdir(exist_ok=True, parents=True) + request.files["file"].save(Path(chunks_directory(_fileid), + chunk_name(_uploadfilename, _chunk))) + + # Check whether upload is complete + chunkpaths = tuple( + Path(chunks_directory(_fileid), chunk_name(_uploadfilename, _achunk)) + for _achunk in range(1, _totalchunks+1)) + if all(_file.exists() for _file in chunkpaths): + ### HACK: Break possible race condition ### + # Looks like sometimes, there are multiple threads/requests trying + # to merge one file, leading to race conditions and in some rare + # instances, actual data corruption. This hack is meant to break + # that race condition. + _delays = ( + 101, 103, 107, 109, 113, 127, 131, 137, 139, 149, 151, 157, 163, + 167, 173, 179, 181, 191, 193, 197, 199, 211, 223, 227, 229, 233, + 239, 241, 251, 257, 263, 269, 271, 277, 281, 283, 293) + _lockfile = Path(chunks_directory(_fileid), "merge.lock") + while True: + time.sleep(random.choice(_delays) / 1000) + if (chunks_directory(_fileid).exists() + and not (_lockfile.exists() and _targetfile.exists())): + # merge_files and clean up chunks + _lockfile.touch() + __merge_chunks__(_targetfile, chunkpaths) + _lockfile.unlink() + chunks_directory(_fileid).rmdir() + continue + + if (_targetfile.exists() + and not ( + chunks_directory(_fileid).exists() + and _lockfile.exists())): + # merge complete + break + + # There is still a thread that's merging this file + continue + ### END: HACK: Break possible race condition ### + + if _targetfile.exists(): + return jsonify({ + "uploaded-file": _targetfile.name, + "original-name": _uploadfilename, + "message": "File was uploaded successfully!", + "statuscode": 200 + }), 200 + return jsonify({ + "uploaded-file": _targetfile.name, + "original-name": _uploadfilename, + "message": "Uploaded file is missing!", + "statuscode": 404 + }), 404 + return jsonify({ + "message": f"Chunk {int(_chunk)} uploaded successfully.", + "statuscode": 201 + }), 201 + except Exception as exc:# pylint: disable=[broad-except] + msg = "Error processing uploaded file chunks." + app.logger.error(msg, exc_info=True, stack_info=True) + return jsonify({ + "message": msg, + "error": type(exc).__name__, + "error-description": " ".join(str(arg) for arg in exc.args), + "error-trace": traceback.format_exception(exc) + }), 500 diff --git a/uploader/genotypes/__init__.py b/uploader/genotypes/__init__.py new file mode 100644 index 0000000..d0025d6 --- /dev/null +++ b/uploader/genotypes/__init__.py @@ -0,0 +1 @@ +"""The Genotypes module.""" diff --git a/uploader/genotypes/models.py b/uploader/genotypes/models.py new file mode 100644 index 0000000..4c3e634 --- /dev/null +++ b/uploader/genotypes/models.py @@ -0,0 +1,102 @@ +"""Functions for handling genotypes.""" +from typing import Optional +from datetime import datetime + +import MySQLdb as mdb +from MySQLdb.cursors import Cursor, DictCursor +from flask import current_app as app + +from gn_libs.mysqldb import debug_query + +def genocode_by_population( + conn: mdb.Connection, population_id: int) -> tuple[dict, ...]: + """Get the allele/genotype codes.""" + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute("SELECT * FROM GenoCode WHERE InbredSetId=%s", + (population_id,)) + return tuple(dict(item) for item in cursor.fetchall()) + + +def genotype_markers_count(conn: mdb.Connection, species_id: int) -> int: + """Find the total count of the genotype markers for a species.""" + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute( + "SELECT COUNT(Name) AS markers_count FROM Geno WHERE SpeciesId=%s", + (species_id,)) + return int(cursor.fetchone()["markers_count"]) + + +def genotype_markers( + conn: mdb.Connection, + species_id: int, + offset: int = 0, + limit: Optional[int] = None +) -> tuple[dict, ...]: + """Retrieve markers from the database.""" + _query = "SELECT * FROM Geno WHERE SpeciesId=%s" + if bool(limit) and limit > 0:# type: ignore[operator] + _query = _query + f" LIMIT {limit} OFFSET {offset}" + + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute(_query, (species_id,)) + debug_query(cursor, app.logger) + return tuple(dict(row) for row in cursor.fetchall()) + + +def genotype_dataset( + conn: mdb.Connection, + species_id: int, + population_id: int, + dataset_id: Optional[int] = None +) -> Optional[dict]: + """Retrieve genotype datasets from the database. + + Apparently, you should only ever have one genotype dataset for a population. + """ + _query = ( + "SELECT gf.* FROM Species AS s INNER JOIN InbredSet AS iset " + "ON s.Id=iset.SpeciesId INNER JOIN GenoFreeze AS gf " + "ON iset.Id=gf.InbredSetId " + "WHERE s.Id=%s AND iset.Id=%s") + _params = (species_id, population_id) + if bool(dataset_id): + _query = _query + " AND gf.Id=%s" + _params = _params + (dataset_id,)# type: ignore[assignment] + + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute(_query, _params) + debug_query(cursor, app.logger) + result = cursor.fetchone() + if bool(result): + return dict(result) + return None + + +def save_new_dataset( + cursor: Cursor, + population_id: int, + name: str, + fullname: str, + shortname: str +) -> dict: + """Save a new genotype dataset into the database.""" + params = { + "InbredSetId": population_id, + "Name": name, + "FullName": fullname, + "ShortName": shortname, + "CreateTime": datetime.now().date().isoformat(), + "public": 2, + "confidentiality": 0, + "AuthorisedUsers": None + } + cursor.execute( + "INSERT INTO GenoFreeze(" + "Name, FullName, ShortName, CreateTime, public, InbredSetId, " + "confidentiality, AuthorisedUsers" + ") VALUES (" + "%(Name)s, %(FullName)s, %(ShortName)s, %(CreateTime)s, %(public)s, " + "%(InbredSetId)s, %(confidentiality)s, %(AuthorisedUsers)s" + ")", + params) + return {**params, "Id": cursor.lastrowid} diff --git a/uploader/genotypes/views.py b/uploader/genotypes/views.py new file mode 100644 index 0000000..54c2444 --- /dev/null +++ b/uploader/genotypes/views.py @@ -0,0 +1,207 @@ +"""Views for the genotypes.""" +from MySQLdb.cursors import DictCursor +from gn_libs.mysqldb import database_connection +from flask import (flash, + request, + url_for, + redirect, + Blueprint, + render_template, + current_app as app) + +from uploader.ui import make_template_renderer +from uploader.oauth2.client import oauth2_post +from uploader.authorisation import require_login +from uploader.route_utils import generic_select_population +from uploader.datautils import safe_int, enumerate_sequence +from uploader.species.models import all_species, species_by_id +from uploader.monadic_requests import make_either_error_handler +from uploader.request_checks import with_species, with_population +from uploader.population.models import population_by_species_and_id + +from .models import (genotype_markers, + genotype_dataset, + save_new_dataset, + genotype_markers_count, + genocode_by_population) + +genotypesbp = Blueprint("genotypes", __name__) +render_template = make_template_renderer("genotypes") + +@genotypesbp.route("populations/genotypes", methods=["GET"]) +@require_login +def index(): + """Direct entry-point for genotypes.""" + with database_connection(app.config["SQL_URI"]) as conn: + if not bool(request.args.get("species_id")): + return render_template("genotypes/index.html", + species=all_species(conn), + activelink="genotypes") + + species_id = request.args.get("species_id") + if species_id == "CREATE-SPECIES": + return redirect(url_for( + "species.create_species", + return_to="species.populations.genotypes.select_population")) + + species = species_by_id(conn, request.args.get("species_id")) + if not bool(species): + flash(f"Could not find species with ID '{request.args.get('species_id')}'!", + "alert-danger") + return redirect(url_for("species.populations.genotypes.index")) + return redirect(url_for("species.populations.genotypes.select_population", + species_id=species["SpeciesId"])) + + +@genotypesbp.route("/<int:species_id>/populations/genotypes/select-population", + methods=["GET"]) +@require_login +@with_species(redirect_uri="species.populations.genotypes.index") +def select_population(species: dict, species_id: int):# pylint: disable=[unused-argument] + """Select the population under which the genotypes go.""" + return generic_select_population( + species, + "genotypes/select-population.html", + request.args.get("population_id") or "", + "species.populations.genotypes.select_population", + "species.populations.genotypes.list_genotypes", + "genotypes", + "Invalid population selected!") + + +@genotypesbp.route( + "/<int:species_id>/populations/<int:population_id>/genotypes", + methods=["GET"]) +@require_login +@with_population(species_redirect_uri="species.populations.genotypes.index", + redirect_uri="species.populations.genotypes.select_population") +def list_genotypes(species: dict, population: dict, **kwargs):# pylint: disable=[unused-argument] + """List genotype details for species and population.""" + with database_connection(app.config["SQL_URI"]) as conn: + return render_template("genotypes/list-genotypes.html", + species=species, + population=population, + genocode=genocode_by_population( + conn, population["Id"]), + total_markers=genotype_markers_count( + conn, species["SpeciesId"]), + dataset=genotype_dataset(conn, + species["SpeciesId"], + population["Id"]), + activelink="list-genotypes") + + +@genotypesbp.route( + "/<int:species_id>/populations/<int:population_id>/genotypes/list-markers", + methods=["GET"]) +@require_login +@with_population(species_redirect_uri="species.populations.genotypes.index", + redirect_uri="species.populations.genotypes.select_population") +def list_markers( + species: dict, + population: dict, + **kwargs +):# pylint: disable=[unused-argument] + """List a species' genetic markers.""" + with database_connection(app.config["SQL_URI"]) as conn: + start_from = max(safe_int(request.args.get("start_from") or 0), 0) + count = safe_int(request.args.get("count") or 20) + return render_template("genotypes/list-markers.html", + species=species, + population=population, + total_markers=genotype_markers_count( + conn, species["SpeciesId"]), + start_from=start_from, + count=count, + markers=enumerate_sequence( + genotype_markers(conn, + species["SpeciesId"], + offset=start_from, + limit=count), + start=start_from+1), + activelink="list-markers") + +@genotypesbp.route( + "/<int:species_id>/populations/<int:population_id>/genotypes/datasets/" + "<int:dataset_id>/view", + methods=["GET"]) +@require_login +def view_dataset(species_id: int, population_id: int, dataset_id: int): + """View details regarding a specific dataset.""" + with database_connection(app.config["SQL_URI"]) as conn: + species = species_by_id(conn, species_id) + if not bool(species): + flash("Invalid species provided!", "alert-danger") + return redirect(url_for("species.populations.genotypes.index")) + + population = population_by_species_and_id( + conn, species_id, population_id) + if not bool(population): + flash("Invalid population selected!", "alert-danger") + return redirect(url_for( + "species.populations.genotypes.select_population", + species_id=species_id)) + + dataset = genotype_dataset(conn, species_id, population_id, dataset_id) + if not bool(dataset): + flash("Could not find such a dataset!", "alert-danger") + return redirect(url_for( + "species.populations.genotypes.list_genotypes", + species_id=species_id, + population_id=population_id)) + + return render_template("genotypes/view-dataset.html", + species=species, + population=population, + dataset=dataset, + activelink="view-dataset") + + +@genotypesbp.route( + "/<int:species_id>/populations/<int:population_id>/genotypes/datasets/" + "create", + methods=["GET", "POST"]) +@require_login +@with_population(species_redirect_uri="species.populations.genotypes.index", + redirect_uri="species.populations.genotypes.select_population") +def create_dataset(species: dict, population: dict, **kwargs):# pylint: disable=[unused-argument] + """Create a genotype dataset.""" + with (database_connection(app.config["SQL_URI"]) as conn, + conn.cursor(cursorclass=DictCursor) as cursor): + if request.method == "GET": + return render_template("genotypes/create-dataset.html", + species=species, + population=population, + activelink="create-dataset") + + form = request.form + new_dataset = save_new_dataset( + cursor, + population["Id"], + form["geno-dataset-name"], + form["geno-dataset-fullname"], + form["geno-dataset-shortname"]) + + def __success__(_success): + flash("Successfully created genotype dataset.", "alert-success") + return redirect(url_for( + "species.populations.genotypes.list_genotypes", + species_id=species["SpeciesId"], + population_id=population["Id"])) + + return oauth2_post( + "auth/resource/genotypes/create", + json={ + **dict(request.form), + "species_id": species["SpeciesId"], + "population_id": population["Id"], + "dataset_id": new_dataset["Id"], + "dataset_name": form["geno-dataset-name"], + "dataset_fullname": form["geno-dataset-fullname"], + "dataset_shortname": form["geno-dataset-shortname"], + "public": "on" + } + ).either( + make_either_error_handler( + "There was an error creating the genotype dataset."), + __success__) diff --git a/uploader/input_validation.py b/uploader/input_validation.py index 9abe742..627c69e 100644 --- a/uploader/input_validation.py +++ b/uploader/input_validation.py @@ -1,14 +1,19 @@ """Input validation utilities""" +import re +import json +import base64 from typing import Any def is_empty_string(value: str) -> bool: """Check whether as string is empty""" return (isinstance(value, str) and value.strip() == "") + def is_empty_input(value: Any) -> bool: """Check whether user provided an empty value.""" return (value is None or is_empty_string(value)) + def is_integer_input(value: Any) -> bool: """ Check whether user provided a value that can be parsed into an integer. @@ -25,3 +30,42 @@ def is_integer_input(value: Any) -> bool: __is_int__(value, 10) or __is_int__(value, 8) or __is_int__(value, 16)))) + + +def is_valid_representative_name(repr_name: str) -> bool: + """ + Check whether the given representative name is a valid according to our rules. + + Parameters + ---------- + repr_name: a string of characters. + + Checks For + ---------- + * The name MUST start with an alphabet [a-zA-Z] + * The name MUST end with an alphabet [a-zA-Z] or number [0-9] + * The name MUST be composed of alphabets [a-zA-Z], numbers [0-9], + underscores (_) and/or hyphens (-). + + Returns + ------- + Boolean indicating whether or not the name is valid. + """ + pattern = re.compile(r"^[a-zA-Z]+[a-zA-Z0-9_-]*[a-zA-Z0-9]$") + return bool(pattern.match(repr_name)) + + +def encode_errors(errors: tuple[tuple[str, str], ...], form) -> bytes: + """Encode form errors into base64 string.""" + return base64.b64encode( + json.dumps({ + "errors": dict(errors), + "original_formdata": dict(form) + }).encode("utf8")) + + +def decode_errors(errorstr) -> dict[str, dict]: + """Decode errors from base64 string""" + if not bool(errorstr): + return {"errors": {}, "original_formdata": {}} + return json.loads(base64.b64decode(errorstr.encode("utf8")).decode("utf8")) diff --git a/uploader/jobs.py b/uploader/jobs.py index 21889da..5968c03 100644 --- a/uploader/jobs.py +++ b/uploader/jobs.py @@ -1,6 +1,8 @@ """Handle jobs""" import os import sys +import uuid +import json import shlex import subprocess from uuid import UUID, uuid4 @@ -10,7 +12,9 @@ from typing import Union, Optional from redis import Redis from flask import current_app as app -JOBS_PREFIX = "JOBS" +from functional_tools import take + +JOBS_PREFIX = "jobs" class JobNotFound(Exception): """Raised if we try to retrieve a non-existent job.""" @@ -37,7 +41,8 @@ def error_filename(jobid, error_dir): "Compute the path of the file where errors will be dumped." return f"{error_dir}/job_{jobid}.error" -def initialise_job(# pylint: disable=[too-many-arguments] +def initialise_job( + # pylint: disable=[too-many-arguments, too-many-positional-arguments] rconn: Redis, rprefix: str, jobid: str, command: list, job_type: str, ttl_seconds: int = 86400, extra_meta: Optional[dict] = None) -> dict: "Initialise a job 'object' and put in on redis" @@ -50,7 +55,8 @@ def initialise_job(# pylint: disable=[too-many-arguments] name=job_key(rprefix, jobid), time=timedelta(seconds=ttl_seconds)) return the_job -def build_file_verification_job(#pylint: disable=[too-many-arguments] +def build_file_verification_job( + #pylint: disable=[too-many-arguments, too-many-positional-arguments] redis_conn: Redis, dburi: str, redisuri: str, @@ -73,7 +79,8 @@ def build_file_verification_job(#pylint: disable=[too-many-arguments] "filename": os.path.basename(filepath), "percent": 0 }) -def data_insertion_job(# pylint: disable=[too-many-arguments] +def data_insertion_job( + # pylint: disable=[too-many-arguments, too-many-positional-arguments] redis_conn: Redis, filepath: str, filetype: str, totallines: int, speciesid: int, platformid: int, datasetid: int, databaseuri: str, redisuri: str, ttl_seconds: int) -> dict: @@ -128,3 +135,33 @@ def update_stdout_stderr(rconn: Redis, contents = thejob.get(stream, '') new_contents = contents + bytes_read.decode("utf-8") rconn.hset(name=job_key(rprefix, jobid), key=stream, value=new_contents) + + +def job_errors( + rconn: Redis, + prefix: str, + job_id: Union[str, uuid.UUID], + count: int = 100 +) -> list: + """Fetch job errors""" + return take( + ( + json.loads(error) + for key in rconn.keys(f"{prefix}:{str(job_id)}:*:errors:*") + for error in rconn.lrange(key, 0, -1)), + count) + + +def job_files_metadata( + rconn: Redis, + prefix: str, + job_id: Union[str, uuid.UUID] +) -> dict: + """Get the metadata for specific job file.""" + return { + key.split(":")[-1]: { + **rconn.hgetall(key), + "filetype": key.split(":")[-3] + } + for key in rconn.keys(f"{prefix}:{str(job_id)}:*:metadata*") + } diff --git a/uploader/monadic_requests.py b/uploader/monadic_requests.py index aa34951..eda42d0 100644 --- a/uploader/monadic_requests.py +++ b/uploader/monadic_requests.py @@ -5,13 +5,12 @@ from typing import Union, Optional, Callable import requests from requests.models import Response from pymonad.either import Left, Right, Either -from flask import ( - flash, - request, - redirect, - render_template, - current_app as app, - escape as flask_escape) +from markupsafe import escape as markupsafe_escape +from flask import (flash, + request, + redirect, + render_template, + current_app as app) # HTML Status codes indicating a successful request. SUCCESS_CODES = (200, 201, 202, 203, 204, 205, 206, 207, 208, 226) @@ -40,9 +39,9 @@ def make_error_handler( trace=traceback.format_exception(resp_or_exc)) if isinstance(resp_or_exc, Response): flash("The authorisation server responded with " - f"({flask_escape(resp_or_exc.status_code)}, " - f"{flask_escape(resp_or_exc.reason)}) for the request to " - f"'{flask_escape(resp_or_exc.request.url)}'", + f"({markupsafe_escape(resp_or_exc.status_code)}, " + f"{markupsafe_escape(resp_or_exc.reason)}) for the request to " + f"'{markupsafe_escape(resp_or_exc.request.url)}'", "alert-danger") return redirect_to @@ -60,6 +59,11 @@ def get(url, params=None, **kwargs) -> Either: :rtype: pymonad.either.Either """ + timeout = kwargs.get("timeout") + kwargs = {key: val for key,val in kwargs.items() if key != "timeout"} + if timeout is None: + timeout = (9.13, 20) + try: resp = requests.get(url, params=params, **kwargs) if resp.status_code in SUCCESS_CODES: @@ -77,6 +81,11 @@ def post(url, data=None, json=None, **kwargs) -> Either: :rtype: pymonad.either.Either """ + timeout = kwargs.get("timeout") + kwargs = {key: val for key,val in kwargs.items() if key != "timeout"} + if timeout is None: + timeout = (9.13, 20) + try: resp = requests.post(url, data=data, json=json, **kwargs) if resp.status_code in SUCCESS_CODES: @@ -84,3 +93,22 @@ def post(url, data=None, json=None, **kwargs) -> Either: return Left(resp) except requests.exceptions.RequestException as exc: return Left(exc) + + +def make_either_error_handler(msg): + """Make generic error handler for pymonads Either objects.""" + def __fail__(error): + if issubclass(type(error), Exception): + app.logger.debug("\n\n%s (Exception)\n\n", msg, exc_info=True) + raise error + if issubclass(type(error), Response): + try: + _data = error.json() + except Exception as _exc: + raise Exception(error.content) from _exc# pylint: disable=[broad-exception-raised] + raise Exception(_data)# pylint: disable=[broad-exception-raised] + + app.logger.debug("\n\n%s\n\n", msg) + raise Exception(error)# pylint: disable=[broad-exception-raised] + + return __fail__ diff --git a/uploader/oauth2/client.py b/uploader/oauth2/client.py index a3e4ba3..12fbf80 100644 --- a/uploader/oauth2/client.py +++ b/uploader/oauth2/client.py @@ -1,5 +1,8 @@ """OAuth2 client utilities.""" import json +import time +import uuid +import random from datetime import datetime, timedelta from urllib.parse import urljoin, urlparse @@ -8,10 +11,9 @@ from flask import request, current_app as app from pymonad.either import Left, Right, Either -from authlib.jose import jwt from authlib.common.urls import url_decode -from authlib.jose import KeySet, JsonWebKey from authlib.jose.errors import BadSignatureError +from authlib.jose import KeySet, JsonWebKey, JsonWebToken from authlib.integrations.requests_client import OAuth2Session from uploader import session @@ -36,49 +38,41 @@ def oauth2_clientsecret(): return app.config["OAUTH2_CLIENT_SECRET"] -def __make_token_validator__(keys: KeySet): - """Make a token validator function.""" - def __validator__(token: dict): - for key in keys.keys: - try: - jwt.decode(token["access_token"], key) - return Right(token) - except BadSignatureError: - pass - - return Left("INVALID-TOKEN") - - return __validator__ - - -def __validate_token__(sess_info): - """Validate that the token is really from the auth server.""" - info = sess_info - info["user"]["token"] = info["user"]["token"].then(__make_token_validator__( - KeySet([JsonWebKey.import_key(key) for key in info.get( - "auth_server_jwks", {}).get( - "jwks", {"keys": []})["keys"]]))) - return session.save_session_info(info) - - -def __update_auth_server_jwks__(sess_info): - """Updates the JWKs every 2 hours or so.""" - jwks = sess_info.get("auth_server_jwks") - if bool(jwks): - last_updated = jwks.get("last-updated") - now = datetime.now().timestamp() - if bool(last_updated) and (now - last_updated) < timedelta(hours=2).seconds: - return __validate_token__({**sess_info, "auth_server_jwks": jwks}) - - jwksuri = urljoin(authserver_uri(), "auth/public-jwks") - return __validate_token__({ - **sess_info, - "auth_server_jwks": { +def __fetch_auth_server_jwks__() -> KeySet: + """Fetch the JWKs from the auth server.""" + return KeySet([ + JsonWebKey.import_key(key) + for key in requests.get( + urljoin(authserver_uri(), "auth/public-jwks") + ).json()["jwks"]]) + + +def __update_auth_server_jwks__(jwks) -> KeySet: + """Update the JWKs from the servers if necessary.""" + last_updated = jwks["last-updated"] + now = datetime.now().timestamp() + # Maybe the `two_hours` variable below can be made into a configuration + # variable and passed in to this function + two_hours = timedelta(hours=2).seconds + if bool(last_updated) and (now - last_updated) < two_hours: + return jwks["jwks"] + + return session.set_auth_server_jwks(__fetch_auth_server_jwks__()) + + +def auth_server_jwks() -> KeySet: + """Fetch the auth-server JSON Web Keys information.""" + _jwks = session.session_info().get("auth_server_jwks") or {} + if bool(_jwks): + return __update_auth_server_jwks__({ + "last-updated": _jwks["last-updated"], "jwks": KeySet([ - JsonWebKey.import_key(key) - for key in requests.get(jwksuri).json()["jwks"]]).as_dict(), - "last-updated": datetime.now().timestamp() - } + JsonWebKey.import_key(key) for key in _jwks.get( + "jwks", {"keys": []})["keys"]]) + }) + + return __update_auth_server_jwks__({ + "last-updated": (datetime.now() - timedelta(hours=3)).timestamp() }) @@ -111,15 +105,66 @@ def oauth2_client(): ("client_secret_post", __json_auth__)) return client - __update_auth_server_jwks__(session.session_info()) - return session.user_token().either( + def __token_expired__(token): + """Check whether the token has expired.""" + jwks = auth_server_jwks() + if bool(jwks): + for jwk in jwks.keys: + try: + jwt = JsonWebToken(["RS256"]).decode( + token["access_token"], key=jwk) + if bool(jwt.get("exp")): + return datetime.now().timestamp() > jwt["exp"] + except BadSignatureError as _bse: + pass + + return False + + def __delay__(): + """Do a tiny delay.""" + time.sleep(random.choice(tuple(i/1000.0 for i in range(0,100)))) + + def __refresh_token__(token): + """Refresh the token if necessary — synchronise amongst threads.""" + if __token_expired__(token): + __delay__() + if session.is_token_refreshing(): + while session.is_token_refreshing(): + __delay__() + + return session.user_token().either(None, lambda _tok: _tok) + + session.toggle_token_refreshing() + _client = __client__(token) + _client.get(urljoin(authserver_uri(), "auth/user/")) + session.toggle_token_refreshing() + return _client.token + + return token + + return session.user_token().then(__refresh_token__).either( lambda _notok: __client__(None), __client__) +def fetch_user_details() -> Either: + """Retrieve user details from the auth server""" + suser = session.session_info()["user"] + if suser["email"] == "anon@ymous.user": + udets = oauth2_get("auth/user/").then( + lambda usrdets: session.set_user_details({ + "user_id": uuid.UUID(usrdets["user_id"]), + "name": usrdets["name"], + "email": usrdets["email"], + "token": session.user_token()})) + return udets + return Right(suser) + + def user_logged_in(): """Check whether the user has logged in.""" suser = session.session_info()["user"] + fetch_user_details() return suser["logged_in"] and suser["token"].is_right() @@ -163,7 +208,7 @@ def oauth2_get(url, **kwargs) -> Either: return Right(resp.json()) return Left(resp) except Exception as exc:#pylint: disable=[broad-except] - app.logger.error("Error retriving data from auth server: (GET %s)", + app.logger.error("Error retrieving data from auth server: (GET %s)", _uri, exc_info=True) return Left(exc) @@ -195,7 +240,7 @@ def oauth2_post(url, data=None, json=None, **kwargs):#pylint: disable=[redefined return Right(resp.json()) return Left(resp) except Exception as exc:#pylint: disable=[broad-except] - app.logger.error("Error retriving data from auth server: (POST %s)", + app.logger.error("Error retrieving data from auth server: (POST %s)", _uri, exc_info=True) return Left(exc) diff --git a/uploader/oauth2/views.py b/uploader/oauth2/views.py index 61037f3..db4ef61 100644 --- a/uploader/oauth2/views.py +++ b/uploader/oauth2/views.py @@ -24,22 +24,24 @@ from .client import ( user_logged_in, authserver_uri, oauth2_clientid, + fetch_user_details, oauth2_clientsecret) oauth2 = Blueprint("oauth2", __name__) + @oauth2.route("/code") def authorisation_code(): """Receive authorisation code from auth server and use it to get token.""" def __process_error__(resp_or_exception): app.logger.debug("ERROR: (%s)", resp_or_exception) flash("There was an error retrieving the authorisation token.", - "alert-danger") + "alert alert-danger") return redirect("/") def __fail_set_user_details__(_failure): app.logger.debug("Fetching user details fails: %s", _failure) - flash("Could not retrieve the user details", "alert-danger") + flash("Could not retrieve the user details", "alert alert-danger") return redirect("/") def __success_set_user_details__(_success): @@ -48,19 +50,13 @@ def authorisation_code(): def __success__(token): session.set_user_token(token) - return oauth2_get("auth/user/").then( - lambda usrdets: session.set_user_details({ - "user_id": uuid.UUID(usrdets["user_id"]), - "name": usrdets["name"], - "email": usrdets["email"], - "token": session.user_token(), - "logged_in": True})).either( + return fetch_user_details().either( __fail_set_user_details__, __success_set_user_details__) code = request.args.get("code", "").strip() if not bool(code): - flash("AuthorisationError: No code was provided.", "alert-danger") + flash("AuthorisationError: No code was provided.", "alert alert-danger") return redirect("/") baseurl = urlparse(request.base_url, scheme=request.scheme) @@ -116,7 +112,7 @@ def logout(): _user = session_info["user"] _user_str = f"{_user['name']} ({_user['email']})" session.clear_session_info() - flash("Successfully logged out.", "alert-success") + flash("Successfully signed out.", "alert alert-success") return redirect("/") if user_logged_in(): @@ -134,5 +130,5 @@ def logout(): cleanup_thunk=lambda: __unset_session__( session.session_info())), lambda res: __unset_session__(session.session_info())) - flash("There is no user that is currently logged in.", "alert-info") + flash("There is no user that is currently logged in.", "alert alert-info") return redirect("/") diff --git a/uploader/parse.py b/uploader/parse.py deleted file mode 100644 index dea4f95..0000000 --- a/uploader/parse.py +++ /dev/null @@ -1,178 +0,0 @@ -"""File parsing module""" -import os - -import jsonpickle -from redis import Redis -from flask import flash, request, url_for, redirect, Blueprint, render_template -from flask import current_app as app - -from quality_control.errors import InvalidValue, DuplicateHeading - -from uploader import jobs -from uploader.dbinsert import species_by_id -from uploader.db_utils import with_db_connection -from uploader.authorisation import require_login - -parsebp = Blueprint("parse", __name__) - -def isinvalidvalue(item): - """Check whether item is of type InvalidValue""" - return isinstance(item, InvalidValue) - -def isduplicateheading(item): - """Check whether item is of type DuplicateHeading""" - return isinstance(item, DuplicateHeading) - -@parsebp.route("/parse", methods=["GET"]) -@require_login -def parse(): - """Trigger file parsing""" - errors = False - speciesid = request.args.get("speciesid") - filename = request.args.get("filename") - filetype = request.args.get("filetype") - if speciesid is None: - flash("No species selected", "alert-error error-expr-data") - errors = True - else: - try: - speciesid = int(speciesid) - species = with_db_connection( - lambda con: species_by_id(con, speciesid)) - if not bool(species): - flash("No such species.", "alert-error error-expr-data") - errors = True - except ValueError: - flash("Invalid speciesid provided. Expected an integer.", - "alert-error error-expr-data") - errors = True - - if filename is None: - flash("No file provided", "alert-error error-expr-data") - errors = True - - if filetype is None: - flash("No filetype provided", "alert-error error-expr-data") - errors = True - - if filetype not in ("average", "standard-error"): - flash("Invalid filetype provided", "alert-error error-expr-data") - errors = True - - if filename: - filepath = os.path.join(app.config["UPLOAD_FOLDER"], filename) - if not os.path.exists(filepath): - flash("Selected file does not exist (any longer)", - "alert-error error-expr-data") - errors = True - - if errors: - return redirect(url_for("entry.upload_file")) - - redisurl = app.config["REDIS_URL"] - with Redis.from_url(redisurl, decode_responses=True) as rconn: - job = jobs.launch_job( - jobs.build_file_verification_job( - rconn, app.config["SQL_URI"], redisurl, - speciesid, filepath, filetype, - app.config["JOBS_TTL_SECONDS"]), - redisurl, - f"{app.config['UPLOAD_FOLDER']}/job_errors") - - return redirect(url_for("parse.parse_status", job_id=job["jobid"])) - -@parsebp.route("/status/<job_id>", methods=["GET"]) -def parse_status(job_id: str): - "Retrieve the status of the job" - with Redis.from_url(app.config["REDIS_URL"], decode_responses=True) as rconn: - try: - job = jobs.job(rconn, jobs.jobsnamespace(), job_id) - except jobs.JobNotFound as _exc: - return render_template("no_such_job.html", job_id=job_id), 400 - - error_filename = jobs.error_filename( - job_id, f"{app.config['UPLOAD_FOLDER']}/job_errors") - if os.path.exists(error_filename): - stat = os.stat(error_filename) - if stat.st_size > 0: - return redirect(url_for("parse.fail", job_id=job_id)) - - job_id = job["jobid"] - progress = float(job["percent"]) - status = job["status"] - filename = job.get("filename", "uploaded file") - errors = jsonpickle.decode( - job.get("errors", jsonpickle.encode(tuple()))) - if status in ("success", "aborted"): - return redirect(url_for("parse.results", job_id=job_id)) - - if status == "parse-error": - return redirect(url_for("parse.fail", job_id=job_id)) - - app.jinja_env.globals.update( - isinvalidvalue=isinvalidvalue, - isduplicateheading=isduplicateheading) - return render_template( - "job_progress.html", - job_id = job_id, - job_status = status, - progress = progress, - message = job.get("message", ""), - job_name = f"Parsing '{filename}'", - errors=errors) - -@parsebp.route("/results/<job_id>", methods=["GET"]) -def results(job_id: str): - """Show results of parsing...""" - with Redis.from_url(app.config["REDIS_URL"], decode_responses=True) as rconn: - job = jobs.job(rconn, jobs.jobsnamespace(), job_id) - - if job: - filename = job["filename"] - errors = jsonpickle.decode(job.get("errors", jsonpickle.encode(tuple()))) - app.jinja_env.globals.update( - isinvalidvalue=isinvalidvalue, - isduplicateheading=isduplicateheading) - return render_template( - "parse_results.html", - errors=errors, - job_name = f"Parsing '{filename}'", - user_aborted = job.get("user_aborted"), - job_id=job["jobid"]) - - return render_template("no_such_job.html", job_id=job_id) - -@parsebp.route("/fail/<job_id>", methods=["GET"]) -def fail(job_id: str): - """Handle parsing failure""" - with Redis.from_url(app.config["REDIS_URL"], decode_responses=True) as rconn: - job = jobs.job(rconn, jobs.jobsnamespace(), job_id) - - if job: - error_filename = jobs.error_filename( - job_id, f"{app.config['UPLOAD_FOLDER']}/job_errors") - if os.path.exists(error_filename): - stat = os.stat(error_filename) - if stat.st_size > 0: - return render_template( - "worker_failure.html", job_id=job_id) - - return render_template("parse_failure.html", job=job) - - return render_template("no_such_job.html", job_id=job_id) - -@parsebp.route("/abort", methods=["POST"]) -@require_login -def abort(): - """Handle user request to abort file processing""" - job_id = request.form["job_id"] - - with Redis.from_url(app.config["REDIS_URL"], decode_responses=True) as rconn: - job = jobs.job(rconn, jobs.jobsnamespace(), job_id) - - if job: - rconn.hset(name=jobs.job_key(jobs.jobsnamespace(), job_id), - key="user_aborted", - value=int(True)) - - return redirect(url_for("parse.parse_status", job_id=job_id)) diff --git a/uploader/phenotypes/__init__.py b/uploader/phenotypes/__init__.py new file mode 100644 index 0000000..c17d32c --- /dev/null +++ b/uploader/phenotypes/__init__.py @@ -0,0 +1,2 @@ +"""Package for handling ('classical') phenotype data""" +from .views import phenotypesbp diff --git a/uploader/phenotypes/misc.py b/uploader/phenotypes/misc.py new file mode 100644 index 0000000..cbe3b7f --- /dev/null +++ b/uploader/phenotypes/misc.py @@ -0,0 +1,26 @@ +"""Miscellaneous functions handling phenotypes and phenotypes data.""" +import logging + +logger = logging.getLogger(__name__) + + +def phenotypes_data_differences( + filedata: tuple[dict, ...], dbdata: tuple[dict, ...] +) -> tuple[dict, ...]: + """Compute differences between file data and db data""" + diff = tuple() + for filerow, dbrow in zip( + sorted(filedata, key=lambda item: (item["phenotype_id"], item["xref_id"])), + sorted(dbdata, key=lambda item: (item["PhenotypeId"], item["xref_id"]))): + for samplename, value in filerow["data"].items(): + if value != dbrow["data"].get(samplename, {}).get("value"): + diff = diff + ({ + "PhenotypeId": filerow["phenotype_id"], + "xref_id": filerow["xref_id"], + "DataId": dbrow["DataId"], + "StrainId": dbrow["data"].get(samplename, {}).get("StrainId"), + "StrainName": samplename, + "value": value + },) + + return diff diff --git a/uploader/phenotypes/models.py b/uploader/phenotypes/models.py new file mode 100644 index 0000000..c2aeebf --- /dev/null +++ b/uploader/phenotypes/models.py @@ -0,0 +1,396 @@ +"""Database and utility functions for phenotypes.""" +import logging +import tempfile +from pathlib import Path +from functools import reduce +from datetime import datetime +from typing import Optional, Iterable + +import MySQLdb as mdb +from MySQLdb.cursors import Cursor, DictCursor + +from functional_tools import take +from gn_libs.mysqldb import debug_query + +logger = logging.getLogger(__name__) + + +__PHENO_DATA_TABLES__ = { + "PublishData": { + "table": "PublishData", "valueCol": "value", "DataIdCol": "Id"}, + "PublishSE": { + "table": "PublishSE", "valueCol": "error", "DataIdCol": "DataId"}, + "NStrain": { + "table": "NStrain", "valueCol": "count", "DataIdCol": "DataId"} +} + + +def datasets_by_population( + conn: mdb.Connection, + species_id: int, + population_id: int +) -> tuple[dict, ...]: + """Retrieve all of a population's phenotype studies.""" + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute( + "SELECT s.SpeciesId, pf.* FROM Species AS s " + "INNER JOIN InbredSet AS iset ON s.Id=iset.SpeciesId " + "INNER JOIN PublishFreeze AS pf ON iset.Id=pf.InbredSetId " + "WHERE s.Id=%s AND iset.Id=%s;", + (species_id, population_id)) + return tuple(dict(row) for row in cursor.fetchall()) + + +def dataset_by_id(conn: mdb.Connection, + species_id: int, + population_id: int, + dataset_id: int) -> dict: + """Fetch dataset details by identifier""" + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute( + "SELECT Species.SpeciesId, PublishFreeze.* FROM Species " + "INNER JOIN InbredSet ON Species.Id=InbredSet.SpeciesId " + "INNER JOIN PublishFreeze ON InbredSet.Id=PublishFreeze.InbredSetId " + "WHERE Species.Id=%s AND InbredSet.Id=%s AND PublishFreeze.Id=%s", + (species_id, population_id, dataset_id)) + return dict(cursor.fetchone()) + + +def phenotypes_count(conn: mdb.Connection, + population_id: int, + dataset_id: int) -> int: + """Count the number of phenotypes in the dataset.""" + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute( + "SELECT COUNT(*) AS total_phenos FROM Phenotype AS pheno " + "INNER JOIN PublishXRef AS pxr ON pheno.Id=pxr.PhenotypeId " + "INNER JOIN PublishFreeze AS pf ON pxr.InbredSetId=pf.InbredSetId " + "WHERE pxr.InbredSetId=%s AND pf.Id=%s", + (population_id, dataset_id)) + return int(cursor.fetchone()["total_phenos"]) + + +def phenotype_publication_data(conn, phenotype_id) -> Optional[dict]: + """Retrieve the publication data for a phenotype if it exists.""" + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute( + "SELECT DISTINCT pxr.PhenotypeId, pub.* FROM PublishXRef AS pxr " + "INNER JOIN Publication as pub ON pxr.PublicationId=pub.Id " + "WHERE pxr.PhenotypeId=%s", + (phenotype_id,)) + res = cursor.fetchone() + if res is None: + return res + return dict(res) + + +def dataset_phenotypes(conn: mdb.Connection, + population_id: int, + dataset_id: int, + offset: int = 0, + limit: Optional[int] = None) -> tuple[dict, ...]: + """Fetch the actual phenotypes.""" + _query = ( + "SELECT pheno.*, pxr.Id AS xref_id, pxr.InbredSetId, ist.InbredSetCode FROM Phenotype AS pheno " + "INNER JOIN PublishXRef AS pxr ON pheno.Id=pxr.PhenotypeId " + "INNER JOIN PublishFreeze AS pf ON pxr.InbredSetId=pf.InbredSetId " + "INNER JOIN InbredSet AS ist ON pf.InbredSetId=ist.Id " + "WHERE pxr.InbredSetId=%s AND pf.Id=%s") + ( + f" LIMIT {limit} OFFSET {offset}" if bool(limit) else "") + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute(_query, (population_id, dataset_id)) + debug_query(cursor, logger) + return tuple(dict(row) for row in cursor.fetchall()) + + +def __phenotype_se__(cursor: Cursor, xref_id, dataids_and_strainids): + """Fetch standard-error values (if they exist) for a phenotype.""" + paramstr = ", ".join(["(%s, %s)"] * len(dataids_and_strainids)) + flat = tuple(item for sublist in dataids_and_strainids for item in sublist) + cursor.execute("SELECT * FROM PublishSE WHERE (DataId, StrainId) IN " + f"({paramstr})", + flat) + debug_query(cursor, logger) + _se = { + (row["DataId"], row["StrainId"]): { + "DataId": row["DataId"], + "StrainId": row["StrainId"], + "error": row["error"] + } + for row in cursor.fetchall() + } + + cursor.execute("SELECT * FROM NStrain WHERE (DataId, StrainId) IN " + f"({paramstr})", + flat) + debug_query(cursor, logger) + _n = { + (row["DataId"], row["StrainId"]): { + "DataId": row["DataId"], + "StrainId": row["StrainId"], + "count": row["count"] + } + for row in cursor.fetchall() + } + + keys = set(tuple(_se.keys()) + tuple(_n.keys())) + return { + key: {"xref_id": xref_id, **_se.get(key,{}), **_n.get(key,{})} + for key in keys + } + +def __organise_by_phenotype__(pheno, row): + """Organise disparate data rows into phenotype 'objects'.""" + _pheno = pheno.get(row["Id"]) + return { + **pheno, + row["Id"]: { + "Id": row["Id"], + "Pre_publication_description": row["Pre_publication_description"], + "Post_publication_description": row["Post_publication_description"], + "Original_description": row["Original_description"], + "Units": row["Units"], + "Pre_publication_abbreviation": row["Pre_publication_abbreviation"], + "Post_publication_abbreviation": row["Post_publication_abbreviation"], + "xref_id": row["pxr.Id"], + "DataId": row["DataId"], + "data": { + **(_pheno["data"] if bool(_pheno) else {}), + (row["DataId"], row["StrainId"]): { + "DataId": row["DataId"], + "StrainId": row["StrainId"], + "mean": row["mean"], + "Locus": row["Locus"], + "LRS": row["LRS"], + "additive": row["additive"], + "Sequence": row["Sequence"], + "comments": row["comments"], + "value": row["value"], + "StrainName": row["Name"], + "StrainName2": row["Name2"], + "StrainSymbol": row["Symbol"], + "StrainAlias": row["Alias"] + } + } + } + } + + +def __merge_pheno_data_and_se__(data, sedata) -> dict: + """Merge phenotype data with the standard errors.""" + return { + key: {**value, **sedata.get(key, {})} + for key, value in data.items() + } + + +def phenotype_by_id( + conn: mdb.Connection, + species_id: int, + population_id: int, + dataset_id: int, + xref_id +) -> Optional[dict]: + """Fetch a specific phenotype.""" + _dataquery = ("SELECT pheno.*, pxr.*, pd.*, str.*, iset.InbredSetCode " + "FROM Phenotype AS pheno " + "INNER JOIN PublishXRef AS pxr ON pheno.Id=pxr.PhenotypeId " + "INNER JOIN PublishData AS pd ON pxr.DataId=pd.Id " + "INNER JOIN Strain AS str ON pd.StrainId=str.Id " + "INNER JOIN StrainXRef AS sxr ON str.Id=sxr.StrainId " + "INNER JOIN PublishFreeze AS pf ON sxr.InbredSetId=pf.InbredSetId " + "INNER JOIN InbredSet AS iset ON pf.InbredSetId=iset.InbredSetId " + "WHERE " + "(str.SpeciesId, pxr.InbredSetId, pf.Id, pxr.Id)=(%s, %s, %s, %s)") + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute(_dataquery, + (species_id, population_id, dataset_id, xref_id)) + _pheno: dict = reduce(__organise_by_phenotype__, cursor.fetchall(), {}) + if bool(_pheno) and len(_pheno.keys()) == 1: + _pheno = tuple(_pheno.values())[0] + return { + **_pheno, + "data": tuple(__merge_pheno_data_and_se__( + _pheno["data"], + __phenotype_se__( + cursor, xref_id, tuple(_pheno["data"].keys())) + ).values()) + } + if bool(_pheno) and len(_pheno.keys()) > 1: + raise Exception( + "We found more than one phenotype with the same identifier!") + + return None + + +def phenotypes_data(conn: mdb.Connection, + population_id: int, + dataset_id: int, + offset: int = 0, + limit: Optional[int] = None) -> tuple[dict, ...]: + """Fetch the data for the phenotypes.""" + # — Phenotype -> PublishXRef -> PublishData -> Strain -> StrainXRef -> PublishFreeze + _query = ("SELECT pheno.*, pxr.*, pd.*, str.*, iset.InbredSetCode " + "FROM Phenotype AS pheno " + "INNER JOIN PublishXRef AS pxr ON pheno.Id=pxr.PhenotypeId " + "INNER JOIN PublishData AS pd ON pxr.DataId=pd.Id " + "INNER JOIN Strain AS str ON pd.StrainId=str.Id " + "INNER JOIN StrainXRef AS sxr ON str.Id=sxr.StrainId " + "INNER JOIN PublishFreeze AS pf ON sxr.InbredSetId=pf.InbredSetId " + "INNER JOIN InbredSet AS iset ON pf.InbredSetId=iset.InbredSetId " + "WHERE pxr.InbredSetId=%s AND pf.Id=%s") + ( + f" LIMIT {limit} OFFSET {offset}" if bool(limit) else "") + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute(_query, (population_id, dataset_id)) + debug_query(cursor, logger) + return tuple(dict(row) for row in cursor.fetchall()) + + +def save_new_dataset(cursor: Cursor, + population_id: int, + dataset_name: str, + dataset_fullname: str, + dataset_shortname: str) -> dict: + """Create a new phenotype dataset.""" + params = { + "population_id": population_id, + "dataset_name": dataset_name, + "dataset_fullname": dataset_fullname, + "dataset_shortname": dataset_shortname, + "created": datetime.now().date().isoformat(), + "public": 2, + "confidentiality": 0, + "users": None + } + cursor.execute( + "INSERT INTO PublishFreeze(Name, FullName, ShortName, CreateTime, " + "public, InbredSetId, confidentiality, AuthorisedUsers) " + "VALUES(%(dataset_name)s, %(dataset_fullname)s, %(dataset_shortname)s, " + "%(created)s, %(public)s, %(population_id)s, %(confidentiality)s, " + "%(users)s)", + params) + debug_query(cursor, logger) + return {**params, "Id": cursor.lastrowid} + + +def phenotypes_data_by_ids( + conn: mdb.Connection, + inbred_pheno_xref: dict[str, int] +) -> tuple[dict, ...]: + """Fetch all phenotype data, filtered by the `inbred_pheno_xref` mapping.""" + _paramstr = ",".join(["(%s, %s, %s)"] * len(inbred_pheno_xref)) + _query = ("SELECT " + "pub.PubMed_ID, pheno.*, pxr.*, pd.*, str.*, iset.InbredSetCode " + "FROM Publication AS pub " + "RIGHT JOIN PublishXRef AS pxr0 ON pub.Id=pxr0.PublicationId " + "INNER JOIN Phenotype AS pheno ON pxr0.PhenotypeId=pheno.id " + "INNER JOIN PublishXRef AS pxr ON pheno.Id=pxr.PhenotypeId " + "INNER JOIN PublishData AS pd ON pxr.DataId=pd.Id " + "INNER JOIN Strain AS str ON pd.StrainId=str.Id " + "INNER JOIN StrainXRef AS sxr ON str.Id=sxr.StrainId " + "INNER JOIN PublishFreeze AS pf ON sxr.InbredSetId=pf.InbredSetId " + "INNER JOIN InbredSet AS iset ON pf.InbredSetId=iset.InbredSetId " + f"WHERE (pxr.InbredSetId, pheno.Id, pxr.Id) IN ({_paramstr}) " + "ORDER BY pheno.Id") + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute(_query, tuple(item for row in inbred_pheno_xref + for item in (row["population_id"], + row["phenoid"], + row["xref_id"]))) + debug_query(cursor, logger) + return tuple( + reduce(__organise_by_phenotype__, cursor.fetchall(), {}).values()) + + +def create_new_phenotypes(conn: mdb.Connection, + phenotypes: Iterable[dict]) -> tuple[dict, ...]: + """Add entirely new phenotypes to the database.""" + _phenos = tuple() + with conn.cursor(cursorclass=DictCursor) as cursor: + while True: + batch = take(phenotypes, 1000) + if len(batch) == 0: + break + + cursor.executemany( + ("INSERT INTO " + "Phenotype(Pre_publication_description, Original_description, Units, Authorized_Users) " + "VALUES (%s, %s, %s, 'robwilliams')"), + tuple((row["id"], row["description"], row["units"]) + for row in batch)) + paramstr = ", ".join(["%s"] * len(batch)) + cursor.execute( + "SELECT * FROM Phenotype WHERE Pre_publication_description IN " + f"({paramstr})", + tuple(item["id"] for item in batch)) + _phenos = _phenos + tuple({ + "phenotype_id": row["Id"], + "id": row["Pre_publication_description"], + "description": row["Original_description"], + "units": row["Units"] + } for row in cursor.fetchall()) + + return _phenos + + +def save_phenotypes_data( + conn: mdb.Connection, + table: str, + data: Iterable[dict] +) -> int: + """Save new phenotypes data into the database.""" + _table_details = __PHENO_DATA_TABLES__[table] + with conn.cursor(cursorclass=DictCursor) as cursor: + _count = 0 + while True: + batch = take(data, 100000) + if len(batch) == 0: + logger.warning("Got an empty batch. This needs investigation.") + break + + logger.debug("Saving batch of %s items.", len(batch)) + cursor.executemany( + (f"INSERT INTO {_table_details['table']}" + f"({_table_details['DataIdCol']}, StrainId, {_table_details['valueCol']}) " + "VALUES " + f"(%(data_id)s, %(sample_id)s, %(value)s) "), + tuple(batch)) + debug_query(cursor, logger) + _count = _count + len(batch) + + + logger.debug("Saved a total of %s data rows", _count) + return _count + + +def quick_save_phenotypes_data( + conn: mdb.Connection, + table: str, + dataitems: Iterable[dict], + tmpdir: Path +) -> int: + """Save data items to the database, but using """ + _table_details = __PHENO_DATA_TABLES__[table] + with (tempfile.NamedTemporaryFile( + prefix=f"{table}_data", mode="wt", dir=tmpdir) as tmpfile, + conn.cursor(cursorclass=DictCursor) as cursor): + _count = 0 + logger.debug("Write data rows to text file.") + for row in dataitems: + tmpfile.write( + f'{row["data_id"]}\t{row["sample_id"]}\t{row["value"]}\n') + _count = _count + 1 + tmpfile.flush() + + logger.debug("Load text file into database (table: %s)", + _table_details["table"]) + cursor.execute( + f"LOAD DATA LOCAL INFILE '{tmpfile.name}' " + f"INTO TABLE {_table_details['table']} " + "(" + f"{_table_details['DataIdCol']}, " + "StrainId, " + f"{_table_details['valueCol']}" + ")") + debug_query(cursor, logger) + return _count diff --git a/uploader/phenotypes/views.py b/uploader/phenotypes/views.py new file mode 100644 index 0000000..bc15f2d --- /dev/null +++ b/uploader/phenotypes/views.py @@ -0,0 +1,1200 @@ +"""Views handling ('classical') phenotypes.""" +import sys +import csv +import uuid +import json +import logging +import tempfile +from typing import Any +from pathlib import Path +from zipfile import ZipFile +from functools import wraps, reduce +from logging import INFO, ERROR, DEBUG, FATAL, CRITICAL, WARNING +from urllib.parse import urljoin, urlparse, ParseResult, urlunparse, urlencode + +import datetime +from datetime import timedelta + +from redis import Redis +from pymonad.either import Left +from requests.models import Response +from MySQLdb.cursors import DictCursor +from werkzeug.utils import secure_filename + +from gn_libs import sqlite3 +from gn_libs import jobs as gnlibs_jobs +from gn_libs.jobs.jobs import JobNotFound +from gn_libs.mysqldb import database_connection +from gn_libs import monadic_requests as mrequests + +from authlib.jose import jwt +from flask import (flash, + request, + url_for, + jsonify, + redirect, + Blueprint, + send_file, + current_app as app) + +# from r_qtl import r_qtl2 as rqtl2 +from r_qtl import r_qtl2_qc as rqc +from r_qtl import exceptions as rqe + + +from uploader import jobs +from uploader import session +from uploader.files import save_file#, fullpath +from uploader.ui import make_template_renderer +from uploader.oauth2.client import oauth2_post +from uploader.authorisation import require_login +from uploader.oauth2 import jwks, client as oauth2client +from uploader.route_utils import generic_select_population +from uploader.datautils import safe_int, enumerate_sequence +from uploader.species.models import all_species, species_by_id +from uploader.monadic_requests import make_either_error_handler +from uploader.publications.models import fetch_publication_by_id +from uploader.request_checks import with_species, with_population +from uploader.samples.models import samples_by_species_and_population +from uploader.input_validation import (encode_errors, + decode_errors, + is_valid_representative_name) + +from .models import (dataset_by_id, + phenotype_by_id, + phenotypes_count, + save_new_dataset, + dataset_phenotypes, + datasets_by_population, + phenotypes_data_by_ids, + phenotype_publication_data) + +phenotypesbp = Blueprint("phenotypes", __name__) +render_template = make_template_renderer("phenotypes") + +_FAMILIES_WITH_SE_AND_N_ = ( + "Reference Populations (replicate average, SE, N)",) + +@phenotypesbp.route("/phenotypes", methods=["GET"]) +@require_login +def index(): + """Direct entry-point for phenotypes data handling.""" + with database_connection(app.config["SQL_URI"]) as conn: + if not bool(request.args.get("species_id")): + return render_template("phenotypes/index.html", + species=all_species(conn), + activelink="phenotypes") + + species_id = request.args.get("species_id") + if species_id == "CREATE-SPECIES": + return redirect(url_for( + "species.create_species", + return_to="species.populations.phenotypes.select_population")) + + species = species_by_id(conn, species_id) + if not bool(species): + flash("No such species!", "alert-danger") + return redirect(url_for("species.populations.phenotypes.index")) + return redirect(url_for("species.populations.phenotypes.select_population", + species_id=species["SpeciesId"])) + + +@phenotypesbp.route("<int:species_id>/phenotypes/select-population", + methods=["GET"]) +@require_login +@with_species(redirect_uri="species.populations.phenotypes.index") +def select_population(species: dict, **kwargs):# pylint: disable=[unused-argument] + """Select the population for your phenotypes.""" + return generic_select_population( + species, + "phenotypes/select-population.html", + request.args.get("population_id") or "", + "species.populations.phenotypes.select_population", + "species.populations.phenotypes.list_datasets", + "phenotypes", + "No such population found!") + + + +@phenotypesbp.route( + "<int:species_id>/populations/<int:population_id>/phenotypes/datasets", + methods=["GET"]) +@require_login +@with_population(species_redirect_uri="species.populations.phenotypes.index", + redirect_uri="species.populations.phenotypes.select_population") +def list_datasets(species: dict, population: dict, **kwargs):# pylint: disable=[unused-argument] + """List available phenotype datasets.""" + with database_connection(app.config["SQL_URI"]) as conn: + datasets = datasets_by_population( + conn, species["SpeciesId"], population["Id"]) + if len(datasets) == 1: + return redirect(url_for( + "species.populations.phenotypes.view_dataset", + species_id=species["SpeciesId"], + population_id=population["Id"], + dataset_id=datasets[0]["Id"])) + return render_template("phenotypes/list-datasets.html", + species=species, + population=population, + datasets=datasets, + activelink="list-datasets") + + +def with_dataset( + species_redirect_uri: str, + population_redirect_uri: str, + redirect_uri: str +): + """Ensure the dataset actually exists.""" + def __decorator__(func): + @wraps(func) + @with_population(species_redirect_uri, population_redirect_uri) + def __with_dataset__(**kwargs): + try: + _spcid = int(kwargs["species_id"]) + _popid = int(kwargs["population_id"]) + _dsetid = int(kwargs.get("dataset_id")) + select_dataset_uri = redirect(url_for( + redirect_uri, species_id=_spcid, population_id=_popid)) + if not bool(_dsetid): + flash("You need to select a valid 'dataset_id' value.", + "alert-danger") + return select_dataset_uri + with database_connection(app.config["SQL_URI"]) as conn: + dataset = dataset_by_id(conn, _spcid, _popid, _dsetid) + if not bool(dataset): + flash("You must select a valid dataset.", + "alert-danger") + return select_dataset_uri + except ValueError as _verr: + app.logger.debug( + "Exception converting 'dataset_id' to integer: %s", + kwargs.get("dataset_id"), + exc_info=True) + flash("Expected 'dataset_id' value to be an integer." + "alert-danger") + return select_dataset_uri + return func(dataset=dataset, **kwargs) + return __with_dataset__ + return __decorator__ + + +@phenotypesbp.route( + "<int:species_id>/populations/<int:population_id>/phenotypes/datasets" + "/<int:dataset_id>/view", + methods=["GET"]) +@require_login +@with_dataset( + species_redirect_uri="species.populations.phenotypes.index", + population_redirect_uri="species.populations.phenotypes.select_population", + redirect_uri="species.populations.phenotypes.list_datasets") +def view_dataset(# pylint: disable=[unused-argument] + species: dict, population: dict, dataset: dict, **kwargs): + """View a specific dataset""" + with database_connection(app.config["SQL_URI"]) as conn: + dataset = dataset_by_id( + conn, species["SpeciesId"], population["Id"], dataset["Id"]) + if not bool(dataset): + flash("Could not find such a phenotype dataset!", "alert-danger") + return redirect(url_for( + "species.populations.phenotypes.list_datasets", + species_id=species["SpeciesId"], + population_id=population["Id"])) + + start_at = max(safe_int(request.args.get("start_at") or 0), 0) + count = int(request.args.get("count") or 20) + return render_template("phenotypes/view-dataset.html", + species=species, + population=population, + dataset=dataset, + phenotype_count=phenotypes_count( + conn, population["Id"], dataset["Id"]), + phenotypes=enumerate_sequence( + dataset_phenotypes( + conn, + population["Id"], + dataset["Id"])), + start_from=start_at, + count=count, + activelink="view-dataset") + + +@phenotypesbp.route( + "<int:species_id>/populations/<int:population_id>/phenotypes/datasets" + "/<int:dataset_id>/phenotype/<xref_id>", + methods=["GET"]) +@require_login +@with_dataset( + species_redirect_uri="species.populations.phenotypes.index", + population_redirect_uri="species.populations.phenotypes.select_population", + redirect_uri="species.populations.phenotypes.list_datasets") +def view_phenotype(# pylint: disable=[unused-argument] + species: dict, + population: dict, + dataset: dict, + xref_id: int, + **kwargs +): + """View an individual phenotype from the dataset.""" + def __render__(privileges): + phenotype = phenotype_by_id(conn, + species["SpeciesId"], + population["Id"], + dataset["Id"], + xref_id) + def __non_empty__(value) -> bool: + if isinstance(value, str): + return value.strip() != "" + return bool(value) + + return render_template( + "phenotypes/view-phenotype.html", + species=species, + population=population, + dataset=dataset, + xref_id=xref_id, + phenotype=phenotype, + has_se=any(bool(item.get("error")) for item in phenotype["data"]), + publish_data={ + key.replace("_", " "): val + for key,val in + (phenotype_publication_data(conn, phenotype["Id"]) or {}).items() + if (key in ("PubMed_ID", "Authors", "Title", "Journal") + and __non_empty__(val)) + }, + privileges=(privileges + ### For demo! Do not commit this part + + ("group:resource:edit-resource", + "group:resource:delete-resource",) + ### END: For demo! Do not commit this part + ), + activelink="view-phenotype") + + def __fail__(error): + if isinstance(error, Response) and error.json() == "No linked resource!": + return __render__(tuple()) + return make_either_error_handler( + "There was an error fetching the roles and privileges.")(error) + + with database_connection(app.config["SQL_URI"]) as conn: + return oauth2_post( + "/auth/resource/phenotypes/individual/linked-resource", + json={ + "species_id": species["SpeciesId"], + "population_id": population["Id"], + "dataset_id": dataset["Id"], + "xref_id": xref_id + } + ).then( + lambda resource: tuple( + privilege["privilege_id"] for role in resource["roles"] + for privilege in role["privileges"]) + ).then(__render__).either(__fail__, lambda resp: resp) + + +@phenotypesbp.route( + "<int:species_id>/populations/<int:population_id>/phenotypes/datasets/create", + methods=["GET", "POST"]) +@require_login +@with_population( + species_redirect_uri="species.populations.phenotypes.index", + redirect_uri="species.populations.phenotypes.select_population") +def create_dataset(species: dict, population: dict, **kwargs):# pylint: disable=[unused-argument] + """Create a new phenotype dataset.""" + with (database_connection(app.config["SQL_URI"]) as conn, + conn.cursor(cursorclass=DictCursor) as cursor): + if request.method == "GET": + return render_template("phenotypes/create-dataset.html", + activelink="create-dataset", + species=species, + population=population, + **decode_errors( + request.args.get("error_values", ""))) + + form = request.form + _errors: tuple[tuple[str, str], ...] = tuple() + if not is_valid_representative_name( + (form.get("dataset-name") or "").strip()): + _errors = _errors + (("dataset-name", "Invalid dataset name."),) + + if not bool((form.get("dataset-fullname") or "").strip()): + _errors = _errors + (("dataset-fullname", + "You must provide a value for 'Full Name'."),) + + if bool(_errors) > 0: + return redirect(url_for( + "species.populations.phenotypes.create_dataset", + species_id=species["SpeciesId"], + population_id=population["Id"], + error_values=encode_errors(_errors, form))) + + dataset_shortname = ( + form["dataset-shortname"] or form["dataset-name"]).strip() + _pheno_dataset = save_new_dataset( + cursor, + population["Id"], + form["dataset-name"].strip(), + form["dataset-fullname"].strip(), + dataset_shortname) + return redirect(url_for("species.populations.phenotypes.list_datasets", + species_id=species["SpeciesId"], + population_id=population["Id"])) + + +def process_phenotypes_rqtl2_bundle(error_uri): + """Process phenotypes from the uploaded R/qtl2 bundle.""" + _redisuri = app.config["REDIS_URL"] + _sqluri = app.config["SQL_URI"] + try: + ## Handle huge files here... + phenobundle = save_file(request.files["phenotypes-bundle"], + Path(app.config["UPLOAD_FOLDER"])) + rqc.validate_bundle(phenobundle) + return phenobundle + except AssertionError as _aerr: + app.logger.debug("File upload error!", exc_info=True) + flash("Expected a zipped bundle of files with phenotypes' " + "information.", + "alert-danger") + return error_uri + except rqe.RQTLError as rqtlerr: + app.logger.debug("Bundle validation error!", exc_info=True) + flash("R/qtl2 Error: " + " ".join(rqtlerr.args), "alert-danger") + return error_uri + + +def process_phenotypes_individual_files(error_uri): + """Process the uploaded individual files.""" + form = request.form + cdata = { + "sep": form["file-separator"], + "comment.char": form["file-comment-character"], + "na.strings": form["file-na"].split(" "), + } + bundlepath = Path(app.config["UPLOAD_FOLDER"], + f"{str(uuid.uuid4()).replace('-', '')}.zip") + with ZipFile(bundlepath,mode="w") as zfile: + for rqtlkey, formkey in (("phenocovar", "phenotype-descriptions"), + ("pheno", "phenotype-data"), + ("phenose", "phenotype-se"), + ("phenonum", "phenotype-n")): + cdata[f"{rqtlkey}_transposed"] = ( + (form.get(f"{formkey}-transposed") or "off") == "on") + + if form.get("resumable-upload", False): + # Chunked upload of large files was used + filedata = json.loads(form[formkey]) + zfile.write( + Path(app.config["UPLOAD_FOLDER"], filedata["uploaded-file"]), + arcname=filedata["original-name"]) + cdata[rqtlkey] = cdata.get(rqtlkey, []) + [filedata["original-name"]] + else: + # TODO: Check this path: fix any bugs. + _sentfile = request.files[formkey] + if not bool(_sentfile): + flash(f"Expected file ('{formkey}') was not provided.", + "alert-danger") + return error_uri + + filepath = save_file( + _sentfile, Path(app.config["UPLOAD_FOLDER"]), hashed=False) + zfile.write( + Path(app.config["UPLOAD_FOLDER"], filepath), + arcname=filepath.name) + cdata[rqtlkey] = cdata.get(rqtlkey, []) + [filepath.name] + + + zfile.writestr("control_data.json", data=json.dumps(cdata, indent=2)) + + return bundlepath + + +@phenotypesbp.route( + "<int:species_id>/populations/<int:population_id>/phenotypes/datasets" + "/<int:dataset_id>/add-phenotypes", + methods=["GET", "POST"]) +@require_login +@with_dataset( + species_redirect_uri="species.populations.phenotypes.index", + population_redirect_uri="species.populations.phenotypes.select_population", + redirect_uri="species.populations.phenotypes.list_datasets") +def add_phenotypes(species: dict, population: dict, dataset: dict, **kwargs):# pylint: disable=[unused-argument, too-many-locals] + """Add one or more phenotypes to the dataset.""" + use_bundle = request.args.get("use_bundle", "").lower() == "true" + add_phenos_uri = redirect(url_for( + "species.populations.phenotypes.add_phenotypes", + species_id=species["SpeciesId"], + population_id=population["Id"], + dataset_id=dataset["Id"])) + _redisuri = app.config["REDIS_URL"] + _sqluri = app.config["SQL_URI"] + with (Redis.from_url(_redisuri, decode_responses=True) as rconn, + # database_connection(_sqluri) as conn, + # conn.cursor(cursorclass=DictCursor) as cursor + ): + if request.method == "GET": + today = datetime.date.today() + return render_template( + ("phenotypes/add-phenotypes-with-rqtl2-bundle.html" + if use_bundle else "phenotypes/add-phenotypes-raw-files.html"), + species=species, + population=population, + dataset=dataset, + monthnames=( + "January", "February", "March", "April", + "May", "June", "July", "August", + "September", "October", "November", + "December"), + current_month=today.strftime("%B"), + current_year=int(today.strftime("%Y")), + families_with_se_and_n=_FAMILIES_WITH_SE_AND_N_, + use_bundle=use_bundle, + activelink="add-phenotypes") + + phenobundle = (process_phenotypes_rqtl2_bundle(add_phenos_uri) + if use_bundle else + process_phenotypes_individual_files(add_phenos_uri)) + + _jobid = uuid.uuid4() + _namespace = jobs.jobsnamespace() + _ttl_seconds = app.config["JOBS_TTL_SECONDS"] + _job = jobs.launch_job( + jobs.initialise_job( + rconn, + _namespace, + str(_jobid), + [sys.executable, "-m", "scripts.rqtl2.phenotypes_qc", _sqluri, + _redisuri, _namespace, str(_jobid), str(species["SpeciesId"]), + str(population["Id"]), + # str(dataset["Id"]), + str(phenobundle), + "--loglevel", + logging.getLevelName( + app.logger.getEffectiveLevel() + ).lower(), + "--redisexpiry", + str(_ttl_seconds)], "phenotype_qc", _ttl_seconds, + {"job-metadata": json.dumps({ + "speciesid": species["SpeciesId"], + "populationid": population["Id"], + "datasetid": dataset["Id"], + "bundle": str(phenobundle.absolute()), + **({"publicationid": request.form["publication-id"]} + if request.form.get("publication-id") else {})})}), + _redisuri, + f"{app.config['UPLOAD_FOLDER']}/job_errors") + + app.logger.debug("JOB DETAILS: %s", _job) + jobstatusuri = url_for("species.populations.phenotypes.job_status", + species_id=species["SpeciesId"], + population_id=population["Id"], + dataset_id=dataset["Id"], + job_id=str(_job["jobid"])) + return ((jsonify({ + "redirect-to": jobstatusuri, + "statuscode": 200, + "message": ("Follow the 'redirect-to' URI to see the state " + "of the quality-control job started for your " + "uploaded files.") + }), 200) + if request.form.get("resumable-upload", False) else + redirect(jobstatusuri)) + + +@phenotypesbp.route( + "<int:species_id>/populations/<int:population_id>/phenotypes/datasets" + "/<int:dataset_id>/job/<uuid:job_id>", + methods=["GET"]) +@require_login +@with_dataset( + species_redirect_uri="species.populations.phenotypes.index", + population_redirect_uri="species.populations.phenotypes.select_population", + redirect_uri="species.populations.phenotypes.list_datasets") +def job_status( + species: dict, + population: dict, + dataset: dict, + job_id: uuid.UUID, + **kwargs +):# pylint: disable=[unused-argument] + """Retrieve current status of a particular phenotype QC job.""" + with Redis.from_url(app.config["REDIS_URL"], decode_responses=True) as rconn: + try: + job = jobs.job(rconn, jobs.jobsnamespace(), str(job_id)) + except jobs.JobNotFound as _jnf: + job = None + return render_template("phenotypes/job-status.html", + species=species, + population=population, + dataset=dataset, + job_id=job_id, + job=job, + errors=jobs.job_errors( + rconn, jobs.jobsnamespace(), job['jobid']), + metadata=jobs.job_files_metadata( + rconn, jobs.jobsnamespace(), job['jobid']), + activelink="add-phenotypes") + + +@phenotypesbp.route( + "<int:species_id>/populations/<int:population_id>/phenotypes/datasets" + "/<int:dataset_id>/job/<uuid:job_id>/review", + methods=["GET"]) +@require_login +@with_dataset( + species_redirect_uri="species.populations.phenotypes.index", + population_redirect_uri="species.populations.phenotypes.select_population", + redirect_uri="species.populations.phenotypes.list_datasets") +def review_job_data( + species: dict, + population: dict, + dataset: dict, + job_id: uuid.UUID, + **kwargs +):# pylint: disable=[unused-argument] + """Review data one more time before entering it into the database.""" + with (Redis.from_url(app.config["REDIS_URL"], decode_responses=True) as rconn, + database_connection(app.config["SQL_URI"]) as conn): + try: + job = jobs.job(rconn, jobs.jobsnamespace(), str(job_id)) + except jobs.JobNotFound as _jnf: + job = None + + def __metadata_by_type__(by_type, item): + filetype = item[1]["filetype"] + return { + **by_type, + filetype: (by_type.get(filetype, tuple()) + + ({"filename": item[0], **item[1]},)) + } + metadata: dict[str, Any] = reduce( + __metadata_by_type__, + (jobs.job_files_metadata( + rconn, jobs.jobsnamespace(), job['jobid']) + if job else {}).items(), + {}) + + def __desc__(filetype): + match filetype: + case "phenocovar": + desc = "phenotypes" + case "pheno": + desc = "phenotypes data" + case "phenose": + desc = "phenotypes standard-errors" + case "phenonum": + desc = "phenotypes samples" + case _: + desc = f"unknown file type '{filetype}'." + + return desc + + def __summarise__(filetype, files): + return { + "filetype": filetype, + "number-of-files": len(files), + "total-data-rows": sum( + int(afile["linecount"]) - 1 for afile in files), + "description": __desc__(filetype) + } + + summary = { + filetype: __summarise__(filetype, meta) + for filetype,meta in metadata.items() + } + _job_metadata = json.loads(job["job-metadata"]) + return render_template("phenotypes/review-job-data.html", + species=species, + population=population, + dataset=dataset, + job_id=job_id, + job=job, + summary=summary, + publication=( + fetch_publication_by_id( + conn, int(_job_metadata["publicationid"])) + if _job_metadata.get("publicationid") + else None), + activelink="add-phenotypes") + + +def load_phenotypes_success_handler(job): + """Handle loading new phenotypes into the database successfully.""" + return redirect(url_for( + "species.populations.phenotypes.load_data_success", + species_id=job["metadata"]["species_id"], + population_id=job["metadata"]["population_id"], + dataset_id=job["metadata"]["dataset_id"], + job_id=job["job_id"])) + + +@phenotypesbp.route( + "<int:species_id>/populations/<int:population_id>/phenotypes/datasets" + "/<int:dataset_id>/load-data-to-database", + methods=["POST"]) +@require_login +@with_dataset( + species_redirect_uri="species.populations.phenotypes.index", + population_redirect_uri="species.populations.phenotypes.select_population", + redirect_uri="species.populations.phenotypes.list_datasets") +def load_data_to_database( + species: dict, + population: dict, + dataset: dict, + **kwargs +):# pylint: disable=[unused-argument] + """Load the data from the given QC job into the database.""" + jobs_db = app.config["ASYNCHRONOUS_JOBS_SQLITE_DB"] + with (Redis.from_url(app.config["REDIS_URL"], decode_responses=True) as rconn, + sqlite3.connection(jobs_db) as conn): + qc_job = jobs.job(rconn, jobs.jobsnamespace(), request.form["data-qc-job-id"]) + _meta = json.loads(qc_job["job-metadata"]) + load_job_id = uuid.uuid4() + _loglevel = logging.getLevelName(app.logger.getEffectiveLevel()).lower() + command = [ + sys.executable, + "-u", + "-m", + "scripts.load_phenotypes_to_db", + app.config["SQL_URI"], + jobs_db, + str(load_job_id), + "--log-level", + _loglevel + ] + + def __handle_error__(resp): + return render_template("http-error.html", *resp.json()) + + def __handle_success__(load_job): + app.logger.debug("The phenotypes loading job: %s", load_job) + return redirect(url_for( + "background-jobs.job_status", job_id=load_job["job_id"])) + + issued = datetime.datetime.now() + jwtkey = jwks.newest_jwk_with_rotation( + jwks.jwks_directory(app, "UPLOADER_SECRETS"), + int(app.config["JWKS_ROTATION_AGE_DAYS"])) + + return mrequests.post( + urljoin(oauth2client.authserver_uri(), "auth/token"), + json={ + "grant_type": "urn:ietf:params:oauth:grant-type:jwt-bearer", + "scope": oauth2client.SCOPE, + "assertion": jwt.encode( + header={ + "alg": "RS256", + "typ": "JWT", + "kid": jwtkey.as_dict()["kid"] + }, + payload={ + "iss": str(oauth2client.oauth2_clientid()), + "sub": str(session.user_details()["user_id"]), + "aud": urljoin(oauth2client.authserver_uri(), + "auth/token"), + # TODO: Update expiry time once fix is implemented in + # auth server. + "exp": (issued + timedelta(minutes=5)).timestamp(), + "nbf": int(issued.timestamp()), + "iat": int(issued.timestamp()), + "jti": str(uuid.uuid4()) + }, + key=jwtkey).decode("utf8"), + "client_id": oauth2client.oauth2_clientid() + } + ).then( + lambda token: gnlibs_jobs.initialise_job( + conn, + load_job_id, + command, + "load-new-phenotypes-data", + extra_meta={ + "species_id": species["SpeciesId"], + "population_id": population["Id"], + "dataset_id": dataset["Id"], + "bundle_file": _meta["bundle"], + "publication_id": _meta["publicationid"], + "authserver": oauth2client.authserver_uri(), + "token": token["access_token"], + "success_handler": ( + "uploader.phenotypes.views" + ".load_phenotypes_success_handler") + }) + ).then( + lambda job: gnlibs_jobs.launch_job( + job, + jobs_db, + Path(f"{app.config['UPLOAD_FOLDER']}/job_errors"), + worker_manager="gn_libs.jobs.launcher", + loglevel=_loglevel) + ).either(__handle_error__, __handle_success__) + + +def update_phenotype_metadata(conn, metadata: dict): + """Update a phenotype's basic metadata values.""" + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute("SELECT * FROM Phenotype WHERE Id=%(phenotype-id)s", + metadata) + res = { + **{ + _key: _val for _key,_val in { + key.lower().replace("_", "-"): value + for key, value in (cursor.fetchone() or {}).items() + }.items() + if _key in metadata.keys() + }, + "phenotype-id": metadata.get("phenotype-id") + } + if res == metadata: + return False + + cursor.execute( + "UPDATE Phenotype SET " + "Pre_publication_description=%(pre-publication-description)s, " + "Post_publication_description=%(post-publication-description)s, " + "Original_description=%(original-description)s, " + "Units=%(units)s, " + "Pre_publication_abbreviation=%(pre-publication-abbreviation)s, " + "Post_publication_abbreviation=%(post-publication-abbreviation)s " + "WHERE Id=%(phenotype-id)s", + metadata) + return cursor.rowcount + + +def update_phenotype_values(conn, values): + """Update a phenotype's data values.""" + with conn.cursor() as cursor: + cursor.executemany( + "UPDATE PublishData SET value=%(new)s " + "WHERE Id=%(data_id)s AND StrainId=%(strain_id)s", + tuple(item for item in values if item["new"] is not None)) + cursor.executemany( + "DELETE FROM PublishData " + "WHERE Id=%(data_id)s AND StrainId=%(strain_id)s", + tuple(item for item in values if item["new"] is None)) + return len(values) + return 0 + + +def update_phenotype_se(conn, serrs): + """Update a phenotype's standard-error values.""" + with conn.cursor() as cursor: + cursor.executemany( + "INSERT INTO PublishSE(DataId, StrainId, error) " + "VALUES(%(data_id)s, %(strain_id)s, %(new)s) " + "ON DUPLICATE KEY UPDATE error=VALUES(error)", + tuple(item for item in serrs if item["new"] is not None)) + cursor.executemany( + "DELETE FROM PublishSE " + "WHERE DataId=%(data_id)s AND StrainId=%(strain_id)s", + tuple(item for item in serrs if item["new"] is None)) + return len(serrs) + return 0 + + +def update_phenotype_n(conn, counts): + """Update a phenotype's strain counts.""" + with conn.cursor() as cursor: + cursor.executemany( + "INSERT INTO NStrain(DataId, StrainId, count) " + "VALUES(%(data_id)s, %(strain_id)s, %(new)s) " + "ON DUPLICATE KEY UPDATE count=VALUES(count)", + tuple(item for item in counts if item["new"] is not None)) + cursor.executemany( + "DELETE FROM NStrain " + "WHERE DataId=%(data_id)s AND StrainId=%(strain_id)s", + tuple(item for item in counts if item["new"] is None)) + return len(counts) + + return 0 + + +def update_phenotype_data(conn, data: dict): + """Update the numeric data for a phenotype.""" + def __organise_by_dataid_and_strainid__(acc, current): + _key, dataid, strainid = current[0].split("::") + _keysrc, _keytype = _key.split("-") + newkey = f"{dataid}::{strainid}" + newitem = acc.get(newkey, {}) + newitem[_keysrc] = newitem.get(_keysrc, {}) + newitem[_keysrc][_keytype] = current[1] + return {**acc, newkey: newitem} + + def __separate_items__(acc, row): + key, val = row + return ({ + **acc[0], + key: { + **val["value"], + "changed?": (not val["value"]["new"] == val["value"]["original"]) + } + }, { + **acc[1], + key: { + **val["se"], + "changed?": (not val["se"]["new"] == val["se"]["original"]) + } + },{ + **acc[2], + key: { + **val["n"], + "changed?": (not val["n"]["new"] == val["n"]["original"]) + } + }) + + values, serrs, counts = tuple( + tuple({ + "data_id": row[0].split("::")[0], + "strain_id": row[0].split("::")[1], + "new": row[1]["new"] + } for row in item) + for item in ( + filter(lambda val: val[1]["changed?"], item.items())# type: ignore[arg-type] + for item in reduce(# type: ignore[var-annotated] + __separate_items__, + reduce(__organise_by_dataid_and_strainid__, + data.items(), + {}).items(), + ({}, {}, {})))) + + return (update_phenotype_values(conn, values), + update_phenotype_se(conn, serrs), + update_phenotype_n(conn, counts)) + + +@phenotypesbp.route( + "<int:species_id>/populations/<int:population_id>/phenotypes/datasets" + "/<int:dataset_id>/phenotype/<int:xref_id>/edit", + methods=["GET", "POST"]) +@require_login +@with_dataset( + species_redirect_uri="species.populations.phenotypes.index", + population_redirect_uri="species.populations.phenotypes.select_population", + redirect_uri="species.populations.phenotypes.list_datasets") +def edit_phenotype_data(# pylint: disable=[unused-argument] + species: dict, + population: dict, + dataset: dict, + xref_id: int, + **kwargs +): + """Edit the data for a particular phenotype.""" + def __render__(**kwargs): + processed_kwargs = { + **kwargs, + "privileges": (kwargs.get("privileges", tuple()) + ### For demo! Do not commit this part + + ("group:resource:edit-resource", + "group:resource:delete-resource",) + ### END: For demo! Do not commit this part + ) + } + return render_template( + "phenotypes/edit-phenotype.html", + species=species, + population=population, + dataset=dataset, + xref_id=xref_id, + families_with_se_and_n=_FAMILIES_WITH_SE_AND_N_, + **processed_kwargs, + activelink="edit-phenotype") + + with database_connection(app.config["SQL_URI"]) as conn: + if request.method == "GET": + def __fetch_phenotype__(privileges): + phenotype = phenotype_by_id(conn, + species["SpeciesId"], + population["Id"], + dataset["Id"], + xref_id) + if phenotype is None: + msg = ("Could not find the phenotype with cross-reference ID" + f" '{xref_id}' from dataset '{dataset['FullName']}' " + f" from the '{population['FullName']}' population of " + f" species '{species['FullName']}'.") + return Left({"privileges": privileges, "phenotype-error": msg}) + return {"privileges": privileges, "phenotype": phenotype} + + def __fetch_publication_data__(**kwargs): + pheno = kwargs["phenotype"] + return { + **kwargs, + "publication_data": phenotype_publication_data( + conn, pheno["Id"]) + } + + def __fail__(failure_object): + # process the object + return __render__(failure_object=failure_object) + + return oauth2_post( + "/auth/resource/phenotypes/individual/linked-resource", + json={ + "species_id": species["SpeciesId"], + "population_id": population["Id"], + "dataset_id": dataset["Id"], + "xref_id": xref_id + } + ).then( + lambda resource: tuple( + privilege["privilege_id"] for role in resource["roles"] + for privilege in role["privileges"]) + ).then( + __fetch_phenotype__ + ).then( + lambda args: __fetch_publication_data__(**args) + ).either(__fail__, lambda args: __render__(**args)) + + ## POST + _change = False + match request.form.get("submit", "invalid-action"): + case "update basic metadata": + _change = update_phenotype_metadata(conn, { + key: value.strip() if bool(value.strip()) else None + for key, value in request.form.items() + if key not in ("submit",) + }) + msg = "Basic metadata was updated successfully." + case "update data": + _update = update_phenotype_data(conn, { + key: value.strip() if bool(value.strip()) else None + for key, value in request.form.items() + if key not in ("submit",) + }) + msg = (f"{_update[0]} value rows, {_update[1]} standard-error " + f"rows and {_update[2]} 'N' rows were updated.") + _change = any(item != 0 for item in _update) + case "update publication": + flash("NOT IMPLEMENTED: Would update publication data.", "alert-success") + case _: + flash("Invalid phenotype editing action.", "alert-danger") + + if _change: + flash(msg, "alert-success") + return redirect(url_for( + "species.populations.phenotypes.view_phenotype", + species_id=species["SpeciesId"], + population_id=population["Id"], + dataset_id=dataset["Id"], + xref_id=xref_id)) + + flash("No change was made by the user.", "alert-info") + return redirect(url_for( + "species.populations.phenotypes.edit_phenotype_data", + species_id=species["SpeciesId"], + population_id=population["Id"], + dataset_id=dataset["Id"], + xref_id=xref_id)) + + +def process_phenotype_data_for_download(pheno: dict) -> dict: + """Sanitise data for download.""" + return { + "UniqueIdentifier": f"phId:{pheno['Id']}::xrId:{pheno['xref_id']}", + **{ + key: val for key, val in pheno.items() + if key not in ("Id", "xref_id", "data", "Units") + }, + **{ + data_item["StrainName"]: data_item["value"] + for data_item in pheno.get("data", {}).values() + } + } + + +BULK_EDIT_COMMON_FIELDNAMES = [ + "UniqueIdentifier", + "Post_publication_description", + "Pre_publication_abbreviation", + "Pre_publication_description", + "Original_description", + "Post_publication_abbreviation", + "PubMed_ID" +] + + +@phenotypesbp.route( + "<int:species_id>/populations/<int:population_id>/phenotypes/datasets" + "/<int:dataset_id>/edit-download", + methods=["POST"]) +@require_login +@with_dataset( + species_redirect_uri="species.populations.phenotypes.index", + population_redirect_uri="species.populations.phenotypes.select_population", + redirect_uri="species.populations.phenotypes.list_datasets") +def edit_download_phenotype_data(# pylint: disable=[unused-argument] + species: dict, + population: dict, + dataset: dict, + **kwargs +): + formdata = request.json + with database_connection(app.config["SQL_URI"]) as conn: + samples_list = [ + sample["Name"] for sample in samples_by_species_and_population( + conn, species["SpeciesId"], population["Id"])] + data = ( + process_phenotype_data_for_download(pheno) + for pheno in phenotypes_data_by_ids(conn, tuple({ + "population_id": population["Id"], + "phenoid": row["phenotype_id"], + "xref_id": row["xref_id"] + } for row in formdata))) + + with (tempfile.TemporaryDirectory( + prefix=app.config["TEMPORARY_DIRECTORY"]) as tmpdir): + filename = Path(tmpdir).joinpath("tempfile.tsv") + with open(filename, mode="w") as outfile: + outfile.write( + "# **DO NOT** delete the 'UniqueIdentifier' row. It is used " + "by the system to identify and edit the correct rows and " + "columns in the database.\n") + outfile.write( + "# The '…_description' fields are useful for you to figure out " + "what row you are working on. Changing any of this fields will " + "also update the database, so do be careful.\n") + outfile.write( + "# Leave a field empty to delete the value in the database.\n") + outfile.write( + "# Any line beginning with a '#' character is considered a " + "comment line. This line, and all the lines above it, are " + "all comment lines. Comment lines will be ignored.\n") + writer = csv.DictWriter(outfile, + fieldnames= ( + BULK_EDIT_COMMON_FIELDNAMES + + samples_list), + dialect="excel-tab") + writer.writeheader() + writer.writerows(data) + outfile.flush() + + return send_file( + filename, + mimetype="text/csv", + as_attachment=True, + download_name=secure_filename(f"{dataset['Name']}_data")) + + +@phenotypesbp.route( + "<int:species_id>/populations/<int:population_id>/phenotypes/datasets" + "/<int:dataset_id>/edit-upload", + methods=["GET", "POST"]) +@require_login +@with_dataset( + species_redirect_uri="species.populations.phenotypes.index", + population_redirect_uri="species.populations.phenotypes.select_population", + redirect_uri="species.populations.phenotypes.list_datasets") +def edit_upload_phenotype_data(# pylint: disable=[unused-argument] + species: dict, + population: dict, + dataset: dict, + **kwargs +): + if request.method == "GET": + return render_template( + "phenotypes/bulk-edit-upload.html", + species=species, + population=population, + dataset=dataset, + activelink="edit-phenotype") + + edit_file = save_file(request.files["file-upload-bulk-edit-upload"], + Path(app.config["UPLOAD_FOLDER"])) + + jobs_db = app.config["ASYNCHRONOUS_JOBS_SQLITE_DB"] + with sqlite3.connection(jobs_db) as conn: + job_id = uuid.uuid4() + job_cmd = [ + sys.executable, "-u", + "-m", "scripts.phenotypes_bulk_edit", + app.config["SQL_URI"], + jobs_db, + str(job_id), + "--log-level", + logging.getLevelName( + app.logger.getEffectiveLevel() + ).lower() + ] + app.logger.debug("Phenotype-edit, bulk-upload command: %s", job_cmd) + _job = gnlibs_jobs.launch_job( + gnlibs_jobs.initialise_job(conn, + job_id, + job_cmd, + "phenotype-bulk-edit", + extra_meta = { + "edit-file": str(edit_file), + "species-id": species["SpeciesId"], + "population-id": population["Id"], + "dataset-id": dataset["Id"] + }), + jobs_db, + f"{app.config['UPLOAD_FOLDER']}/job_errors", + worker_manager="gn_libs.jobs.launcher") + + + return redirect(url_for("background-jobs.job_status", + job_id=job_id, + job_type="phenotype-bulk-edit")) + + +@phenotypesbp.route( + "<int:species_id>/populations/<int:population_id>/phenotypes/datasets" + "/<int:dataset_id>/load-data-success/<uuid:job_id>", + methods=["GET"]) +@require_login +@with_dataset( + species_redirect_uri="species.populations.phenotypes.index", + population_redirect_uri="species.populations.phenotypes.select_population", + redirect_uri="species.populations.phenotypes.list_datasets") +def load_data_success( + species: dict, + population: dict, + dataset: dict, + job_id: uuid.UUID, + **kwargs +):# pylint: disable=[unused-argument] + with (database_connection(app.config["SQL_URI"]) as conn, + sqlite3.connection(app.config["ASYNCHRONOUS_JOBS_SQLITE_DB"]) + as jobsconn): + try: + gn2_uri = urlparse(app.config["GN2_SERVER_URL"]) + job = gnlibs_jobs.job(jobsconn, job_id, fulldetails=True) + app.logger.debug("THE JOB: %s", job) + _xref_ids = (str(item) for item + in json.loads(job["metadata"].get("xref_ids", "[]"))) + _publication = fetch_publication_by_id( + conn, int(job["metadata"].get("publication_id", "0"))) + _search_terms = (item for item in + (str(_publication["PubMed_ID"] or ""), + _publication["Authors"], + (_publication["Title"] or "")) + if item != "") + return render_template("phenotypes/load-phenotypes-success.html", + species=species, + population=population, + dataset=dataset, + job=job, + search_page_uri=urlunparse(ParseResult( + scheme=gn2_uri.scheme, + netloc=gn2_uri.netloc, + path="/search", + params="", + query=urlencode({ + "species": species["Name"], + "group": population["Name"], + "type": "Phenotypes", + "dataset": dataset["Name"], + "search_terms_or": ( + # Very long URLs will cause + # errors. + " ".join(_xref_ids) + if len(_xref_ids) <= 100 + else ""), + "search_terms_and": " ".join( + _search_terms).strip(), + "accession_id": "None", + "FormID": "searchResult" + }), + fragment=""))) + except JobNotFound as jnf: + return render_template("jobs/job-not-found.html", job_id=job_id) diff --git a/uploader/platforms/__init__.py b/uploader/platforms/__init__.py new file mode 100644 index 0000000..8cb89c9 --- /dev/null +++ b/uploader/platforms/__init__.py @@ -0,0 +1,2 @@ +"""Module to handle management of genetic platforms.""" +from .views import platformsbp diff --git a/uploader/platforms/models.py b/uploader/platforms/models.py new file mode 100644 index 0000000..0dd9368 --- /dev/null +++ b/uploader/platforms/models.py @@ -0,0 +1,96 @@ +"""Handle db interactions for platforms.""" +from typing import Optional + +import MySQLdb as mdb +from MySQLdb.cursors import Cursor, DictCursor + +def platforms_by_species( + conn: mdb.Connection, + speciesid: int, + offset: int = 0, + limit: Optional[int] = None +) -> tuple[dict, ...]: + """Retrieve platforms by the species""" + _query = ("SELECT * FROM GeneChip WHERE SpeciesId=%s " + "ORDER BY GeneChipName ASC") + if bool(limit) and limit > 0:# type: ignore[operator] + _query = f"{_query} LIMIT {limit} OFFSET {offset}" + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute(_query, (speciesid,)) + return tuple(dict(row) for row in cursor.fetchall()) + + +def species_platforms_count(conn: mdb.Connection, species_id: int) -> int: + """Get the number of platforms in the database for a particular species.""" + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute( + "SELECT COUNT(GeneChipName) AS count FROM GeneChip " + "WHERE SpeciesId=%s", + (species_id,)) + return int(cursor.fetchone()["count"]) + + +def platform_by_id(conn: mdb.Connection, platformid: int) -> Optional[dict]: + """Retrieve a platform by its ID""" + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute("SELECT * FROM GeneChip WHERE Id=%s", + (platformid,)) + result = cursor.fetchone() + if bool(result): + return dict(result) + + return None + + +def platform_by_species_and_id( + conn: mdb.Connection, species_id: int, platformid: int +) -> Optional[dict]: + """Retrieve a platform by its species and ID""" + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute("SELECT * FROM GeneChip WHERE SpeciesId=%s AND Id=%s", + (species_id, platformid)) + result = cursor.fetchone()#pylint: disable=[duplicate-code] + if bool(result): + return dict(result) + + return None + + +def save_new_platform( + # pylint: disable=[too-many-arguments, too-many-positional-arguments] + cursor: Cursor, + species_id: int, + geo_platform: str, + platform_name: str, + platform_shortname: str, + platform_title: str, + go_tree_value: Optional[str] +) -> dict: + """Save a new platform to the database.""" + params = { + "species_id": species_id, + "GeoPlatform": geo_platform, + "GeneChipName": platform_name, + "Name": platform_shortname, + "Title": platform_title, + "GO_tree_value": go_tree_value + } + cursor.execute("SELECT SpeciesId, GeoPlatform FROM GeneChip") + assert (species_id, geo_platform) not in ( + (row["SpeciesId"], row["GeoPlatform"]) for row in cursor.fetchall()) + cursor.execute( + "INSERT INTO " + "GeneChip(SpeciesId, GeneChipName, Name, GeoPlatform, Title, GO_tree_value) " + "VALUES(" + "%(species_id)s, %(GeneChipName)s, %(Name)s, %(GeoPlatform)s, " + "%(Title)s, %(GO_tree_value)s" + ")", + params) + new_id = cursor.lastrowid + cursor.execute("UPDATE GeneChip SET GeneChipId=%s WHERE Id=%s", + (new_id, new_id)) + return { + **params, + "Id": new_id, + "GeneChipId": new_id + } diff --git a/uploader/platforms/views.py b/uploader/platforms/views.py new file mode 100644 index 0000000..d12a9ef --- /dev/null +++ b/uploader/platforms/views.py @@ -0,0 +1,118 @@ +"""The endpoints for the platforms""" +from MySQLdb.cursors import DictCursor +from gn_libs.mysqldb import database_connection +from flask import ( + flash, + request, + url_for, + redirect, + Blueprint, + current_app as app) + +from uploader.ui import make_template_renderer +from uploader.authorisation import require_login +from uploader.species.models import all_species, species_by_id +from uploader.datautils import safe_int, enumerate_sequence + +from .models import (save_new_platform, + platforms_by_species, + species_platforms_count) + +platformsbp = Blueprint("platforms", __name__) +render_template = make_template_renderer("platforms") + +@platformsbp.route("platforms", methods=["GET"]) +@require_login +def index(): + """Entry-point to the platforms feature.""" + with database_connection(app.config["SQL_URI"]) as conn: + if not bool(request.args.get("species_id")): + return render_template( + "platforms/index.html", + species=all_species(conn), + activelink="platforms") + + species_id = request.args.get("species_id") + if species_id == "CREATE-SPECIES": + return redirect(url_for( + "species.create_species", + return_to="species.platforms.list_platforms")) + + species = species_by_id(conn, request.args["species_id"]) + if not bool(species): + flash("No species selected.", "alert-danger") + return redirect(url_for("species.platforms.index")) + + return redirect(url_for("species.platforms.list_platforms", + species_id=species["SpeciesId"])) + + +@platformsbp.route("<int:species_id>/platforms", methods=["GET"]) +@require_login +def list_platforms(species_id: int): + """List all the available genetic sequencing platforms.""" + with database_connection(app.config["SQL_URI"]) as conn: + species = species_by_id(conn, species_id) + if not bool(species): + flash("No species provided.", "alert-danger") + return redirect(url_for("species.platforms.index")) + + start_from = max(safe_int(request.args.get("start_from") or 0), 0) + count = safe_int(request.args.get("count") or 20) + return render_template( + "platforms/list-platforms.html", + species=species, + platforms=enumerate_sequence( + platforms_by_species(conn, + species_id, + offset=start_from, + limit=count), + start=start_from+1), + start_from=start_from, + count=count, + total_platforms=species_platforms_count(conn, species_id), + activelink="list-platforms") + + +@platformsbp.route("<int:species_id>/platforms/create", methods=["GET", "POST"]) +@require_login +def create_platform(species_id: int): + """Create a new genetic sequencing platform.""" + with (database_connection(app.config["SQL_URI"]) as conn, + conn.cursor(cursorclass=DictCursor) as cursor): + species = species_by_id(conn, species_id) + if not bool(species): + flash("No species provided.", "alert-danger") + return redirect(url_for("species.platforms.index")) + + if request.method == "GET": + return render_template( + "platforms/create-platform.html", + species=species, + activelink="create-platform") + + try: + form = request.form + _new_platform = save_new_platform( + cursor, + species_id, + form["geo-platform"], + form["platform-name"], + form["platform-shortname"], + form["platform-title"], + form.get("go-tree-value") or None) + except KeyError as _kerr: + flash(f"Required value for field {_kerr.args[0]} was not provided.", + "alert-danger") + return redirect(url_for("species.platforms.create_platform", + species_id=species_id)) + except AssertionError as _aerr: + flash(f"Platform with GeoPlatform value of '{form['geo-platform']}'" + f" already exists for species '{species['FullName']}'.", + "alert-danger") + return redirect(url_for("species.platforms.create_platform", + species_id=species_id)) + + flash("Platform created successfully", "alert-success") + return redirect(url_for("species.platforms.list_platforms", + species_id=species_id)) diff --git a/uploader/population/__init__.py b/uploader/population/__init__.py new file mode 100644 index 0000000..bf6bf3c --- /dev/null +++ b/uploader/population/__init__.py @@ -0,0 +1,3 @@ +"""Package to handle creation and management of Populations/InbredSets""" + +from .views import popbp diff --git a/uploader/population/models.py b/uploader/population/models.py new file mode 100644 index 0000000..d78a821 --- /dev/null +++ b/uploader/population/models.py @@ -0,0 +1,87 @@ +"""Functions for accessing the database relating to species populations.""" +import MySQLdb as mdb +from MySQLdb.cursors import DictCursor + +def population_by_id(conn: mdb.Connection, population_id) -> dict: + """Get the grouping/population by id.""" + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute("SELECT * FROM InbredSet WHERE InbredSetId=%s", + (population_id,)) + return cursor.fetchone() + +def population_by_species_and_id( + conn: mdb.Connection, species_id, population_id) -> dict: + """Retrieve a population by its identifier and species.""" + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute("SELECT * FROM InbredSet WHERE SpeciesId=%s AND Id=%s", + (species_id, population_id)) + return cursor.fetchone() + +def populations_by_species(conn: mdb.Connection, speciesid) -> tuple: + "Retrieve group (InbredSet) information from the database." + with conn.cursor(cursorclass=DictCursor) as cursor: + query = "SELECT * FROM InbredSet WHERE SpeciesId=%s" + cursor.execute(query, (speciesid,)) + return tuple(cursor.fetchall()) + + return tuple() + + +def population_families(conn) -> tuple: + """Fetch the families under which populations are grouped.""" + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute( + "SELECT DISTINCT(Family) FROM InbredSet WHERE Family IS NOT NULL") + return tuple(row["Family"] for row in cursor.fetchall()) + + +def population_genetic_types(conn) -> tuple: + """Fetch the families under which populations are grouped.""" + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute( + "SELECT DISTINCT(GeneticType) FROM InbredSet WHERE GeneticType IS " + "NOT NULL") + return tuple(row["GeneticType"] for row in cursor.fetchall()) + + +def save_population(cursor: mdb.cursors.Cursor, population_details: dict) -> dict: + """Save the population details to the db.""" + cursor.execute("SELECT DISTINCT(Family), FamilyOrder FROM InbredSet " + "WHERE Family IS NOT NULL AND Family != '' " + "AND FamilyOrder IS NOT NULL " + "ORDER BY FamilyOrder ASC") + _families = { + row["Family"]: int(row["FamilyOrder"]) + for row in cursor.fetchall() + } + params = { + "MenuOrderId": 0, + "InbredSetId": 0, + "public": 2, + **population_details, + "FamilyOrder": _families.get( + population_details["Family"], + max((0,) + tuple(_families.values()))+1) + } + cursor.execute( + "INSERT INTO InbredSet(" + "InbredSetId, InbredSetName, Name, SpeciesId, FullName, " + "public, MappingMethodId, GeneticType, Family, FamilyOrder," + " MenuOrderId, InbredSetCode, Description" + ") " + "VALUES (" + "%(InbredSetId)s, %(InbredSetName)s, %(Name)s, %(SpeciesId)s, " + "%(FullName)s, %(public)s, %(MappingMethodId)s, %(GeneticType)s, " + "%(Family)s, %(FamilyOrder)s, %(MenuOrderId)s, %(InbredSetCode)s, " + "%(Description)s" + ")", + params) + new_id = cursor.lastrowid + cursor.execute("UPDATE InbredSet SET InbredSetId=%s WHERE Id=%s", + (new_id, new_id)) + return { + **params, + "Id": new_id, + "InbredSetId": new_id, + "population_id": new_id + } diff --git a/uploader/upload/rqtl2.py b/uploader/population/rqtl2.py index ff7556d..044cdd4 100644 --- a/uploader/upload/rqtl2.py +++ b/uploader/population/rqtl2.py @@ -3,7 +3,6 @@ import sys import json import traceback from pathlib import Path -from datetime import date from uuid import UUID, uuid4 from functools import partial from zipfile import ZipFile, is_zipfile @@ -12,12 +11,11 @@ from typing import Union, Callable, Optional import MySQLdb as mdb from redis import Redis from MySQLdb.cursors import DictCursor -from werkzeug.utils import secure_filename +from gn_libs.mysqldb import database_connection from flask import ( flash, escape, request, - jsonify, url_for, redirect, Response, @@ -29,18 +27,16 @@ from r_qtl import r_qtl2 from uploader import jobs from uploader.files import save_file, fullpath -from uploader.dbinsert import species as all_species -from uploader.db_utils import with_db_connection, database_connection +from uploader.species.models import all_species +from uploader.db_utils import with_db_connection from uploader.authorisation import require_login -from uploader.db.platforms import platform_by_id, platforms_by_species +from uploader.platforms.models import platform_by_id, platforms_by_species from uploader.db.averaging import averaging_methods, averaging_method_by_id from uploader.db.tissues import all_tissues, tissue_by_id, create_new_tissue -from uploader.db import ( - species_by_id, - save_population, - populations_by_species, - population_by_species_and_id,) +from uploader.population.models import (populations_by_species, + population_by_species_and_id) +from uploader.species.models import species_by_id from uploader.db.datasets import ( geno_dataset_by_id, geno_datasets_by_species_and_population, @@ -61,19 +57,21 @@ rqtl2 = Blueprint("rqtl2", __name__) def select_species(): """Select the species.""" if request.method == "GET": - return render_template("rqtl2/index.html", species=with_db_connection(all_species)) + return render_template("expression-data/rqtl2/index.html", + species=with_db_connection(all_species)) species_id = request.form.get("species_id") species = with_db_connection( lambda conn: species_by_id(conn, species_id)) if bool(species): return redirect(url_for( - "upload.rqtl2.select_population", species_id=species_id)) + "species.populations.expression-data.rqtl2.select_population", + species_id=species_id)) flash("Invalid species or no species selected!", "alert-error error-rqtl2") - return redirect(url_for("upload.rqtl2.select_species")) + return redirect(url_for("expression-data.rqtl2.select_species")) -@rqtl2.route("/upload/species/<int:species_id>/select-population", +@rqtl2.route("<int:species_id>/expression-data/rqtl2/select-population", methods=["GET", "POST"]) @require_login def select_population(species_id: int): @@ -82,11 +80,11 @@ def select_population(species_id: int): species = species_by_id(conn, species_id) if not bool(species): flash("Invalid species selected!", "alert-error error-rqtl2") - return redirect(url_for("upload.rqtl2.select_species")) + return redirect(url_for("expression-data.rqtl2.select_species")) if request.method == "GET": return render_template( - "rqtl2/select-population.html", + "expression-data/rqtl2/select-population.html", species=species, populations=populations_by_species(conn, species_id)) @@ -95,52 +93,14 @@ def select_population(species_id: int): if not bool(population): flash("Invalid Population!", "alert-error error-rqtl2") return redirect( - url_for("upload.rqtl2.select_population", pgsrc="error"), + url_for("expression-data.rqtl2.select_population", pgsrc="error"), code=307) - return redirect(url_for("upload.rqtl2.upload_rqtl2_bundle", + return redirect(url_for("expression-data.rqtl2.upload_rqtl2_bundle", species_id=species["SpeciesId"], population_id=population["InbredSetId"])) -@rqtl2.route("/upload/species/<int:species_id>/create-population", - methods=["POST"]) -@require_login -def create_population(species_id: int): - """Create a new population for the given species.""" - population_page = redirect(url_for("upload.rqtl2.select_population", - species_id=species_id)) - with database_connection(app.config["SQL_URI"]) as conn: - species = species_by_id(conn, species_id) - population_name = request.form.get("inbredset_name", "").strip() - population_fullname = request.form.get("inbredset_fullname", "").strip() - if not bool(species): - flash("Invalid species!", "alert-error error-rqtl2") - return redirect(url_for("upload.rqtl2.select_species")) - if not bool(population_name): - flash("Invalid Population Name!", "alert-error error-rqtl2") - return population_page - if not bool(population_fullname): - flash("Invalid Population Full Name!", "alert-error error-rqtl2") - return population_page - new_population = save_population(conn, { - "SpeciesId": species["SpeciesId"], - "Name": population_name, - "InbredSetName": population_fullname, - "FullName": population_fullname, - "Family": request.form.get("inbredset_family") or None, - "Description": request.form.get("description") or None - }) - - flash("Population created successfully.", "alert-success") - return redirect( - url_for("upload.rqtl2.upload_rqtl2_bundle", - species_id=species_id, - population_id=new_population["population_id"], - pgsrc="create-population"), - code=307) - - class __RequestError__(Exception): #pylint: disable=[invalid-name] """Internal class to avoid pylint's `too-many-return-statements` error.""" @@ -157,18 +117,19 @@ def upload_rqtl2_bundle(species_id: int, population_id: int): conn, species["SpeciesId"], population_id) if not bool(species): flash("Invalid species!", "alert-error error-rqtl2") - return redirect(url_for("upload.rqtl2.select_species")) + return redirect(url_for("expression-data.rqtl2.select_species")) if not bool(population): flash("Invalid Population!", "alert-error error-rqtl2") return redirect( - url_for("upload.rqtl2.select_population", pgsrc="error"), + url_for("expression-data.rqtl2.select_population", pgsrc="error"), code=307) if request.method == "GET" or ( request.method == "POST" and bool(request.args.get("pgsrc"))): - return render_template("rqtl2/upload-rqtl2-bundle-step-01.html", - species=species, - population=population) + return render_template( + "expression-data/rqtl2/upload-rqtl2-bundle-step-01.html", + species=species, + population=population) try: app.logger.debug("Files in the form: %s", request.files) @@ -178,7 +139,7 @@ def upload_rqtl2_bundle(species_id: int, population_id: int): app.logger.debug(traceback.format_exc()) flash("Please provide a valid R/qtl2 zip bundle.", "alert-error error-rqtl2") - return redirect(url_for("upload.rqtl2.upload_rqtl2_bundle", + return redirect(url_for("expression-data.rqtl2.upload_rqtl2_bundle", species_id=species_id, population_id=population_id)) @@ -192,7 +153,7 @@ def upload_rqtl2_bundle(species_id: int, population_id: int): the_file, request.files["rqtl2_bundle_file"].filename)#type: ignore[arg-type] return redirect(url_for( - "upload.rqtl2.rqtl2_bundle_qc_status", jobid=jobid)) + "expression-data.rqtl2.rqtl2_bundle_qc_status", jobid=jobid)) def trigger_rqtl2_bundle_qc( @@ -228,127 +189,6 @@ def trigger_rqtl2_bundle_qc( return jobid -def chunk_name(uploadfilename: str, chunkno: int) -> str: - """Generate chunk name from original filename and chunk number""" - if uploadfilename == "": - raise ValueError("Name cannot be empty!") - if chunkno < 1: - raise ValueError("Chunk number must be greater than zero") - return f"{secure_filename(uploadfilename)}_part_{chunkno:05d}" - - -def chunks_directory(uniqueidentifier: str) -> Path: - """Compute the directory where chunks are temporarily stored.""" - if uniqueidentifier == "": - raise ValueError("Unique identifier cannot be empty!") - return Path(app.config["UPLOAD_FOLDER"], f"tempdir_{uniqueidentifier}") - - -@rqtl2.route(("/upload/species/<int:species_id>/population/<int:population_id>" - "/rqtl2-bundle-chunked"), - methods=["GET"]) -@require_login -def upload_rqtl2_bundle_chunked_get(# pylint: disable=["unused-argument"] - species_id: int, - population_id: int -): - """ - Extension to the `upload_rqtl2_bundle` endpoint above that provides a way - for testing whether all the chunks have been uploaded and to assist with - resuming a failed upload. - """ - fileid = request.args.get("resumableIdentifier", type=str) or "" - filename = request.args.get("resumableFilename", type=str) or "" - chunk = request.args.get("resumableChunkNumber", type=int) or 0 - if not(fileid or filename or chunk): - return jsonify({ - "message": "At least one required query parameter is missing.", - "error": "BadRequest", - "statuscode": 400 - }), 400 - - if Path(chunks_directory(fileid), - chunk_name(filename, chunk)).exists(): - return "OK" - - return jsonify({ - "message": f"Chunk {chunk} was not found.", - "error": "NotFound", - "statuscode": 404 - }), 404 - - -def __merge_chunks__(targetfile: Path, chunkpaths: tuple[Path, ...]) -> Path: - """Merge the chunks into a single file.""" - with open(targetfile, "ab") as _target: - for chunkfile in chunkpaths: - with open(chunkfile, "rb") as _chunkdata: - _target.write(_chunkdata.read()) - - chunkfile.unlink() - return targetfile - - -@rqtl2.route(("/upload/species/<int:species_id>/population/<int:population_id>" - "/rqtl2-bundle-chunked"), - methods=["POST"]) -@require_login -def upload_rqtl2_bundle_chunked_post(species_id: int, population_id: int): - """ - Extension to the `upload_rqtl2_bundle` endpoint above that allows large - files to be uploaded in chunks. - - This should hopefully speed up uploads, and if done right, even enable - resumable uploads - """ - _totalchunks = request.form.get("resumableTotalChunks", type=int) or 0 - _chunk = request.form.get("resumableChunkNumber", default=1, type=int) - _uploadfilename = request.form.get( - "resumableFilename", default="", type=str) or "" - _fileid = request.form.get( - "resumableIdentifier", default="", type=str) or "" - _targetfile = Path(app.config["UPLOAD_FOLDER"], _fileid) - - if _targetfile.exists(): - return jsonify({ - "message": ( - "A file with a similar unique identifier has previously been " - "uploaded and possibly is/has being/been processed."), - "error": "BadRequest", - "statuscode": 400 - }), 400 - - try: - # save chunk data - chunks_directory(_fileid).mkdir(exist_ok=True, parents=True) - request.files["file"].save(Path(chunks_directory(_fileid), - chunk_name(_uploadfilename, _chunk))) - - # Check whether upload is complete - chunkpaths = tuple( - Path(chunks_directory(_fileid), chunk_name(_uploadfilename, _achunk)) - for _achunk in range(1, _totalchunks+1)) - if all(_file.exists() for _file in chunkpaths): - # merge_files and clean up chunks - __merge_chunks__(_targetfile, chunkpaths) - chunks_directory(_fileid).rmdir() - jobid = trigger_rqtl2_bundle_qc( - species_id, population_id, _targetfile, _uploadfilename) - return url_for( - "upload.rqtl2.rqtl2_bundle_qc_status", jobid=jobid) - except Exception as exc:# pylint: disable=[broad-except] - msg = "Error processing uploaded file chunks." - app.logger.error(msg, exc_info=True, stack_info=True) - return jsonify({ - "message": msg, - "error": type(exc).__name__, - "error-description": " ".join(str(arg) for arg in exc.args), - "error-trace": traceback.format_exception(exc) - }), 500 - - return "OK" - - @rqtl2.route("/upload/species/rqtl2-bundle/qc-status/<uuid:jobid>", methods=["GET", "POST"]) @require_login @@ -363,24 +203,25 @@ def rqtl2_bundle_qc_status(jobid: UUID): if bool(messagelistname) else []) jobstatus = thejob["status"] if jobstatus == "error": - return render_template("rqtl2/rqtl2-qc-job-error.html", - job=thejob, - errorsgeneric=json.loads( - thejob.get("errors-generic", "[]")), - errorsgeno=json.loads( - thejob.get("errors-geno", "[]")), - errorspheno=json.loads( - thejob.get("errors-pheno", "[]")), - errorsphenose=json.loads( - thejob.get("errors-phenose", "[]")), - errorsphenocovar=json.loads( - thejob.get("errors-phenocovar", "[]")), - messages=logmessages) + return render_template( + "expression-data/rqtl2/rqtl2-qc-job-error.html", + job=thejob, + errorsgeneric=json.loads( + thejob.get("errors-generic", "[]")), + errorsgeno=json.loads( + thejob.get("errors-geno", "[]")), + errorspheno=json.loads( + thejob.get("errors-pheno", "[]")), + errorsphenose=json.loads( + thejob.get("errors-phenose", "[]")), + errorsphenocovar=json.loads( + thejob.get("errors-phenocovar", "[]")), + messages=logmessages) if jobstatus == "success": jobmeta = json.loads(thejob["job-metadata"]) species = species_by_id(dbconn, jobmeta["speciesid"]) return render_template( - "rqtl2/rqtl2-qc-job-results.html", + "expression-data/rqtl2/rqtl2-qc-job-results.html", species=species, population=population_by_species_and_id( dbconn, species["SpeciesId"], jobmeta["populationid"]), @@ -399,14 +240,14 @@ def rqtl2_bundle_qc_status(jobid: UUID): return None return render_template( - "rqtl2/rqtl2-qc-job-status.html", + "expression-data/rqtl2/rqtl2-qc-job-status.html", job=thejob, geno_percent=compute_percentage(thejob, "geno"), pheno_percent=compute_percentage(thejob, "pheno"), phenose_percent=compute_percentage(thejob, "phenose"), messages=logmessages) except jobs.JobNotFound: - return render_template("rqtl2/no-such-job.html", jobid=jobid) + return render_template("expression-data/rqtl2/no-such-job.html", jobid=jobid) def redirect_on_error(flaskroute, **kwargs): @@ -422,7 +263,7 @@ def check_species(conn: mdb.Connection, formargs: dict) -> Optional[ corresponding species exists in the database. Maybe give the function a better name...""" - speciespage = redirect_on_error("upload.rqtl2.select_species") + speciespage = redirect_on_error("expression-data.rqtl2.select_species") if "species_id" not in formargs: return "You MUST provide the Species identifier.", speciespage @@ -441,7 +282,7 @@ def check_population(conn: mdb.Connection, Maybe give the function a better name...""" poppage = redirect_on_error( - "upload.rqtl2.select_species", species_id=species_id) + "expression-data.rqtl2.select_species", species_id=species_id) if "population_id" not in formargs: return "You MUST provide the Population identifier.", poppage @@ -456,12 +297,12 @@ def check_r_qtl2_bundle(formargs: dict, species_id, population_id) -> Optional[tuple[str, Response]]: """Check for the existence of the R/qtl2 bundle.""" - fileuploadpage = redirect_on_error("upload.rqtl2.upload_rqtl2_bundle", + fileuploadpage = redirect_on_error("expression-data.rqtl2.upload_rqtl2_bundle", species_id=species_id, population_id=population_id) if not "rqtl2_bundle_file" in formargs: return ( - "You MUST provide a R/qtl2 zip bundle for upload.", fileuploadpage) + "You MUST provide a R/qtl2 zip bundle for expression-data.", fileuploadpage) if not Path(fullpath(formargs["rqtl2_bundle_file"])).exists(): return "No R/qtl2 bundle with the given name exists.", fileuploadpage @@ -474,7 +315,7 @@ def check_geno_dataset(conn: mdb.Connection, species_id, population_id) -> Optional[tuple[str, Response]]: """Check for the Genotype dataset.""" - genodsetpg = redirect_on_error("upload.rqtl2.select_dataset_info", + genodsetpg = redirect_on_error("expression-data.rqtl2.select_dataset_info", species_id=species_id, population_id=population_id) if not bool(formargs.get("geno-dataset-id")): @@ -499,7 +340,7 @@ def check_geno_dataset(conn: mdb.Connection, def check_tissue( conn: mdb.Connection,formargs: dict) -> Optional[tuple[str, Response]]: """Check for tissue/organ/biological material.""" - selectdsetpg = redirect_on_error("upload.rqtl2.select_dataset_info", + selectdsetpg = redirect_on_error("expression-data.rqtl2.select_dataset_info", species_id=formargs["species_id"], population_id=formargs["population_id"]) if not bool(formargs.get("tissueid", "").strip()): @@ -527,7 +368,7 @@ def check_probe_study(conn: mdb.Connection, species_id, population_id) -> Optional[tuple[str, Response]]: """Check for the ProbeSet study.""" - dsetinfopg = redirect_on_error("upload.rqtl2.select_dataset_info", + dsetinfopg = redirect_on_error("expression-data.rqtl2.select_dataset_info", species_id=species_id, population_id=population_id) if not bool(formargs.get("probe-study-id")): @@ -545,7 +386,7 @@ def check_probe_dataset(conn: mdb.Connection, species_id, population_id) -> Optional[tuple[str, Response]]: """Check for the ProbeSet dataset.""" - dsetinfopg = redirect_on_error("upload.rqtl2.select_dataset_info", + dsetinfopg = redirect_on_error("expression-data.rqtl2.select_dataset_info", species_id=species_id, population_id=population_id) if not bool(formargs.get("probe-dataset-id")): @@ -583,17 +424,17 @@ def select_geno_dataset(species_id: int, population_id: int): if not bool(geno_dset): flash("No genotype dataset was provided!", "alert-error error-rqtl2") - return redirect(url_for("upload.rqtl2.select_geno_dataset", + return redirect(url_for("expression-data.rqtl2.select_geno_dataset", species_id=species_id, population_id=population_id, pgsrc="error"), code=307) flash("Genotype accepted", "alert-success error-rqtl2") - return redirect(url_for("upload.rqtl2.select_dataset_info", + return redirect(url_for("expression-data.rqtl2.select_dataset_info", species_id=species_id, population_id=population_id, - pgsrc="upload.rqtl2.select_geno_dataset"), + pgsrc="expression-data.rqtl2.select_geno_dataset"), code=307) return with_errors(__thunk__, @@ -610,76 +451,6 @@ def select_geno_dataset(species_id: int, population_id: int): @rqtl2.route(("/upload/species/<int:species_id>/population/<int:population_id>" - "/rqtl2-bundle/create-geno-dataset"), - methods=["POST"]) -@require_login -def create_geno_dataset(species_id: int, population_id: int): - """Create a new geno dataset.""" - with database_connection(app.config["SQL_URI"]) as conn: - def __thunk__(): - sgeno_page = redirect(url_for("upload.rqtl2.select_dataset_info", - species_id=species_id, - population_id=population_id, - pgsrc="error"), - code=307) - errorclasses = "alert-error error-rqtl2 error-rqtl2-create-geno-dataset" - if not bool(request.form.get("dataset-name")): - flash("You must provide the dataset name", errorclasses) - return sgeno_page - if not bool(request.form.get("dataset-fullname")): - flash("You must provide the dataset full name", errorclasses) - return sgeno_page - public = 2 if request.form.get("dataset-public") == "on" else 0 - - with conn.cursor(cursorclass=DictCursor) as cursor: - datasetname = request.form["dataset-name"] - new_dataset = { - "name": datasetname, - "fname": request.form.get("dataset-fullname"), - "sname": request.form.get("dataset-shortname") or datasetname, - "today": date.today().isoformat(), - "pub": public, - "isetid": population_id - } - cursor.execute("SELECT * FROM GenoFreeze WHERE Name=%s", - (datasetname,)) - results = cursor.fetchall() - if bool(results): - flash( - f"A genotype dataset with name '{escape(datasetname)}' " - "already exists.", - errorclasses) - return redirect(url_for("upload.rqtl2.select_dataset_info", - species_id=species_id, - population_id=population_id, - pgsrc="error"), - code=307) - cursor.execute( - "INSERT INTO GenoFreeze(" - "Name, FullName, ShortName, CreateTime, public, InbredSetId" - ") " - "VALUES(" - "%(name)s, %(fname)s, %(sname)s, %(today)s, %(pub)s, %(isetid)s" - ")", - new_dataset) - flash("Created dataset successfully.", "alert-success") - return render_template( - "rqtl2/create-geno-dataset-success.html", - species=species_by_id(conn, species_id), - population=population_by_species_and_id( - conn, species_id, population_id), - rqtl2_bundle_file=request.form["rqtl2_bundle_file"], - geno_dataset={**new_dataset, "id": cursor.lastrowid}) - - return with_errors(__thunk__, - partial(check_species, conn=conn), - partial(check_population, conn=conn, species_id=species_id), - partial(check_r_qtl2_bundle, - species_id=species_id, - population_id=population_id)) - - -@rqtl2.route(("/upload/species/<int:species_id>/population/<int:population_id>" "/rqtl2-bundle/select-tissue"), methods=["POST"]) @require_login @@ -691,10 +462,10 @@ def select_tissue(species_id: int, population_id: int): flash("Invalid tissue selection!", "alert-error error-select-tissue error-rqtl2") - return redirect(url_for("upload.rqtl2.select_dataset_info", + return redirect(url_for("expression-data.rqtl2.select_dataset_info", species_id=species_id, population_id=population_id, - pgsrc="upload.rqtl2.select_geno_dataset"), + pgsrc="expression-data.rqtl2.select_geno_dataset"), code=307) return with_errors(__thunk__, @@ -718,10 +489,10 @@ def create_tissue(species_id: int, population_id: int): """Add new tissue, organ or biological material to the system.""" form = request.form datasetinfopage = redirect( - url_for("upload.rqtl2.select_dataset_info", + url_for("expression-data.rqtl2.select_dataset_info", species_id=species_id, population_id=population_id, - pgsrc="upload.rqtl2.select_geno_dataset"), + pgsrc="expression-data.rqtl2.select_geno_dataset"), code=307) with database_connection(app.config["SQL_URI"]) as conn: tissuename = form.get("tissuename", "").strip() @@ -740,7 +511,7 @@ def create_tissue(species_id: int, population_id: int): tissue = create_new_tissue(conn, tissuename, tissueshortname) flash("Tissue created successfully!", "alert-success") return render_template( - "rqtl2/create-tissue-success.html", + "expression-data/rqtl2/create-tissue-success.html", species=species_by_id(conn, species_id), population=population_by_species_and_id( conn, species_id, population_id), @@ -763,7 +534,7 @@ def select_probeset_study(species_id: int, population_id: int): """Select or create a probeset study.""" with database_connection(app.config["SQL_URI"]) as conn: def __thunk__(): - summary_page = redirect(url_for("upload.rqtl2.select_dataset_info", + summary_page = redirect(url_for("expression-data.rqtl2.select_dataset_info", species_id=species_id, population_id=population_id), code=307) @@ -799,7 +570,7 @@ def select_probeset_dataset(species_id: int, population_id: int): """Select or create a probeset dataset.""" with database_connection(app.config["SQL_URI"]) as conn: def __thunk__(): - summary_page = redirect(url_for("upload.rqtl2.select_dataset_info", + summary_page = redirect(url_for("expression-data.rqtl2.select_dataset_info", species_id=species_id, population_id=population_id), code=307) @@ -843,7 +614,7 @@ def create_probeset_study(species_id: int, population_id: int): def __thunk__(): form = request.form dataset_info_page = redirect( - url_for("upload.rqtl2.select_dataset_info", + url_for("expression-data.rqtl2.select_dataset_info", species_id=species_id, population_id=population_id), code=307) @@ -870,7 +641,7 @@ def create_probeset_study(species_id: int, population_id: int): errorclasses) return dataset_info_page return render_template( - "rqtl2/create-probe-study-success.html", + "expression-data/rqtl2/create-probe-study-success.html", species=species_by_id(conn, species_id), population=population_by_species_and_id( conn, species_id, population_id), @@ -905,7 +676,7 @@ def create_probeset_dataset(species_id: int, population_id: int):#pylint: disabl with database_connection(app.config["SQL_URI"]) as conn: def __thunk__():#pylint: disable=[too-many-return-statements] form = request.form - summary_page = redirect(url_for("upload.rqtl2.select_dataset_info", + summary_page = redirect(url_for("expression-data.rqtl2.select_dataset_info", species_id=species_id, population_id=population_id), code=307) @@ -955,7 +726,7 @@ def create_probeset_dataset(species_id: int, population_id: int):#pylint: disabl errorclasses) return summary_page return render_template( - "rqtl2/create-probe-dataset-success.html", + "expression-data/rqtl2/create-probe-dataset-success.html", species=species_by_id(conn, species_id), population=population_by_species_and_id( conn, species_id, population_id), @@ -1010,7 +781,7 @@ def select_dataset_info(species_id: int, population_id: int): conn,form.get("geno-dataset-id", "").strip()) if "geno" in cdata and not bool(form.get("geno-dataset-id")): return render_template( - "rqtl2/select-geno-dataset.html", + "expression-data/rqtl2/select-geno-dataset.html", species=species, population=population, rqtl2_bundle_file=thefile.name, @@ -1020,7 +791,7 @@ def select_dataset_info(species_id: int, population_id: int): tissue = tissue_by_id(conn, form.get("tissueid", "").strip()) if "pheno" in cdata and not bool(tissue): return render_template( - "rqtl2/select-tissue.html", + "expression-data/rqtl2/select-tissue.html", species=species, population=population, rqtl2_bundle_file=thefile.name, @@ -1034,7 +805,7 @@ def select_dataset_info(species_id: int, population_id: int): conn, form.get("probe-study-id", "").strip()) if "pheno" in cdata and not bool(probeset_study): return render_template( - "rqtl2/select-probeset-study-id.html", + "expression-data/rqtl2/select-probeset-study-id.html", species=species, population=population, rqtl2_bundle_file=thefile.name, @@ -1050,7 +821,7 @@ def select_dataset_info(species_id: int, population_id: int): conn, form.get("probe-dataset-id", "").strip()) if "pheno" in cdata and not bool(probeset_dataset): return render_template( - "rqtl2/select-probeset-dataset.html", + "expression-data/rqtl2/select-probeset-dataset.html", species=species, population=population, rqtl2_bundle_file=thefile.name, @@ -1061,7 +832,7 @@ def select_dataset_info(species_id: int, population_id: int): conn, int(form["probe-study-id"])), avgmethods=averaging_methods(conn)) - return render_template("rqtl2/summary-info.html", + return render_template("expression-data/rqtl2/summary-info.html", species=species, population=population, rqtl2_bundle_file=thefile.name, @@ -1126,7 +897,7 @@ def confirm_bundle_details(species_id: int, population_id: int): redisuri, f"{app.config['UPLOAD_FOLDER']}/job_errors") - return redirect(url_for("upload.rqtl2.rqtl2_processing_status", + return redirect(url_for("expression-data.rqtl2.rqtl2_processing_status", jobid=jobid)) return with_errors(__thunk__, @@ -1164,13 +935,19 @@ def rqtl2_processing_status(jobid: UUID): if thejob["status"] == "error": return render_template( - "rqtl2/rqtl2-job-error.html", job=thejob, messages=logmessages) + "expression-data/rqtl2/rqtl2-job-error.html", + job=thejob, + messages=logmessages) if thejob["status"] == "success": - return render_template("rqtl2/rqtl2-job-results.html", - job=thejob, - messages=logmessages) + return render_template( + "expression-data/rqtl2/rqtl2-job-results.html", + job=thejob, + messages=logmessages) return render_template( - "rqtl2/rqtl2-job-status.html", job=thejob, messages=logmessages) + "expression-data/rqtl2/rqtl2-job-status.html", + job=thejob, + messages=logmessages) except jobs.JobNotFound as _exc: - return render_template("rqtl2/no-such-job.html", jobid=jobid) + return render_template("expression-data/rqtl2/no-such-job.html", + jobid=jobid) diff --git a/uploader/population/views.py b/uploader/population/views.py new file mode 100644 index 0000000..270dd5f --- /dev/null +++ b/uploader/population/views.py @@ -0,0 +1,215 @@ +"""Views dealing with populations/inbredsets""" +import json +import base64 + +from markupsafe import escape +from MySQLdb.cursors import DictCursor +from gn_libs.mysqldb import database_connection +from flask import (flash, + request, + url_for, + redirect, + Blueprint, + current_app as app) + +from uploader.samples.views import samplesbp +from uploader.oauth2.client import oauth2_post +from uploader.ui import make_template_renderer +from uploader.authorisation import require_login +from uploader.genotypes.views import genotypesbp +from uploader.datautils import enumerate_sequence +from uploader.phenotypes.views import phenotypesbp +from uploader.expression_data.views import exprdatabp +from uploader.species.models import all_species, species_by_id +from uploader.monadic_requests import make_either_error_handler +from uploader.input_validation import is_valid_representative_name + +from .models import (save_population, + population_families, + populations_by_species, + population_genetic_types, + population_by_species_and_id) + +__active_link__ = "populations" +popbp = Blueprint("populations", __name__) +popbp.register_blueprint(samplesbp, url_prefix="/") +popbp.register_blueprint(genotypesbp, url_prefix="/") +popbp.register_blueprint(phenotypesbp, url_prefix="/") +popbp.register_blueprint(exprdatabp, url_prefix="/") +render_template = make_template_renderer("populations") + + +@popbp.route("/populations", methods=["GET", "POST"]) +@require_login +def index(): + """Entry point for populations.""" + with database_connection(app.config["SQL_URI"]) as conn: + if not bool(request.args.get("species_id")): + return render_template( + "populations/index.html", + species=all_species(conn), + activelink="populations") + + species_id = request.args.get("species_id") + if species_id == "CREATE-SPECIES": + return redirect(url_for( + "species.create_species", + return_to="species.populations.list_species_populations")) + + species = species_by_id(conn, request.args.get("species_id")) + if not bool(species): + flash("Invalid species identifier provided!", "alert-danger") + return redirect(url_for("species.populations.index")) + return redirect(url_for("species.populations.list_species_populations", + species_id=species["SpeciesId"])) + +@popbp.route("/<int:species_id>/populations", methods=["GET"]) +@require_login +def list_species_populations(species_id: int): + """List a particular species' populations.""" + with database_connection(app.config["SQL_URI"]) as conn: + species = species_by_id(conn, species_id) + if not bool(species): + flash("No species was found for given ID.", "alert-danger") + return redirect(url_for("species.populations.index")) + return render_template( + "populations/list-populations.html", + species=species, + populations=enumerate_sequence(populations_by_species( + conn, species_id)), + activelink="list-populations") + + +@popbp.route("/<int:species_id>/populations/create", methods=["GET", "POST"]) +@require_login +def create_population(species_id: int): + """Create a new population.""" + with (database_connection(app.config["SQL_URI"]) as conn, + conn.cursor(cursorclass=DictCursor) as cursor): + species = species_by_id(conn, species_id) + + if request.method == "GET": + error_values = request.args.get("error_values") + if not bool(error_values): + error_values = base64.b64encode( + '{"errors":{}, "error_values": {}}'.encode("utf8") + ).decode("utf8") + + error_values = json.loads(base64.b64decode( + error_values.encode("utf8")).decode("utf8"))# type: ignore[union-attr] + return render_template( + "populations/create-population.html", + species=species, + families = population_families(conn), + genetic_types = population_genetic_types(conn), + mapping_methods=( + {"id": "0", "value": "No mapping support"}, + {"id": "1", "value": "GEMMA, QTLReaper, R/qtl"}, + {"id": "2", "value": "GEMMA"}, + {"id": "3", "value": "R/qtl"}, + {"id": "4", "value": "GEMMA, PLINK"}), + return_to=(request.args.get("return_to") or ""), + activelink="create-population", + **error_values) + + if not bool(species): + flash("You must select a species.", "alert-danger") + return redirect(url_for("species.populations.index")) + + errors: tuple[tuple[str, str], ...] = tuple() + + population_name = (request.form.get( + "population_name") or "").strip() + if not bool(population_name): + errors = errors + (("population_name", + "You must provide a name for the population!"),) + + if not is_valid_representative_name(population_name): + errors = errors + (( + "population_name", + "The population name can only contain letters, numbers, " + "hyphens and underscores."),) + + population_fullname = (request.form.get( + "population_fullname") or "").strip() + if not bool(population_fullname): + errors = errors + ( + ("population_fullname", "Full Name MUST be provided."),) + + if bool(errors): + values = base64.b64encode( + json.dumps({ + "errors": dict(errors), + "error_values": dict(request.form) + }).encode("utf8")) + return redirect(url_for("species.populations.create_population", + species_id=species["SpeciesId"], + error_values=values)) + + new_population = save_population(cursor, { + "SpeciesId": species["SpeciesId"], + "Name": population_name, + "InbredSetName": population_fullname, + "FullName": population_fullname, + "InbredSetCode": request.form.get("population_code") or None, + "Description": request.form.get("population_description") or None, + "Family": request.form.get("population_family") or None, + "MappingMethodId": request.form.get("population_mapping_method_id"), + "GeneticType": request.form.get("population_genetic_type") or None + }) + + def __flash_success__(_success): + flash("Successfully created population " + f"{escape(new_population['FullName'])}.", + "alert-success") + return_to = request.form.get("return_to") or "" + if return_to: + return redirect(url_for( + return_to, + species_id=species["SpeciesId"], + population_id=new_population["InbredSetId"])) + return redirect(url_for( + "species.populations.view_population", + species_id=species["SpeciesId"], + population_id=new_population["InbredSetId"])) + + app.logger.debug("We begin setting up the privileges here…") + return oauth2_post( + "auth/resource/populations/create", + json={ + **dict(request.form), + "species_id": species_id, + "population_id": new_population["Id"], + "public": "on" + } + ).either( + make_either_error_handler( + "There was an error creating the population"), + __flash_success__) + + +@popbp.route("/<int:species_id>/populations/<int:population_id>", + methods=["GET"]) +@require_login +def view_population(species_id: int, population_id: int): + """View the details of a population.""" + with database_connection(app.config["SQL_URI"]) as conn: + species = species_by_id(conn, species_id) + population = population_by_species_and_id(conn, species_id, population_id) + error = False + + if not bool(species): + flash("You must select a species.", "alert-danger") + error = True + + if not bool(population): + flash("You must select a population.", "alert-danger") + error = True + + if error: + return redirect(url_for("species.populations.index")) + + return render_template("populations/view-population.html", + species=species, + population=population, + activelink="view-population") diff --git a/uploader/publications/__init__.py b/uploader/publications/__init__.py new file mode 100644 index 0000000..7efcabb --- /dev/null +++ b/uploader/publications/__init__.py @@ -0,0 +1,2 @@ +"""Package for handling publications.""" +from .views import pubbp diff --git a/uploader/publications/datatables.py b/uploader/publications/datatables.py new file mode 100644 index 0000000..e07fafd --- /dev/null +++ b/uploader/publications/datatables.py @@ -0,0 +1,52 @@ +"""Fetch data for datatables.""" +import logging +from typing import Optional + +from MySQLdb.cursors import DictCursor + +from gn_libs.mysqldb import Connection, debug_query + +logger = logging.getLogger(__name__) + +def fetch_publications( + conn: Connection, + search: Optional[str] = None, + offset: int = 0, + limit: int = -1 +) -> tuple[dict, int, int, int]: + """Fetch publications from the database.""" + _query = "SELECT * FROM Publication" + _count_query = "SELECT COUNT(*) FROM Publication" + _params = None + _where_clause = "" + _limit_clause = "" + if search is not None and bool(search): + _where_clause = ("WHERE PubMed_ID LIKE %s " + "OR Authors LIKE %s " + "OR Title LIKE %s") + _params = (f"%{search}%",) * 3 + + if limit > 0: + _limit_clause = f"LIMIT {limit} OFFSET {offset}" + + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute("SELECT COUNT(*) FROM Publication") + _total_rows = int(cursor.fetchone()["COUNT(*)"]) + + cursor.execute(f"{_count_query} {_where_clause}", _params) + debug_query(cursor, logger) + _result = cursor.fetchone() + _total_filtered = int(_result["COUNT(*)"] if bool(_result) else 0) + + cursor.execute(f"{_query} {_where_clause} {_limit_clause}", _params) + debug_query(cursor, logger) + _current_filtered = tuple( + {**dict(row), "index": idx} + for idx, row + in enumerate(cursor.fetchall(), start=offset+1)) + + return ( + _current_filtered, + len(_current_filtered), + _total_filtered, + _total_rows) diff --git a/uploader/publications/misc.py b/uploader/publications/misc.py new file mode 100644 index 0000000..fca6f71 --- /dev/null +++ b/uploader/publications/misc.py @@ -0,0 +1,25 @@ +"""Miscellaneous functions dealing with publications.""" + + +def publications_differences( + filedata: tuple[dict, ...], + dbdata: tuple[dict, ...], + pubmedid2pubidmap: tuple[dict, ...] +) -> tuple[dict, ...]: + """Compute the differences between file data and db data""" + diff = tuple() + for filerow, dbrow in zip( + sorted(filedata, key=lambda item: ( + item["phenotype_id"], item["xref_id"])), + sorted(dbdata, key=lambda item: ( + item["PhenotypeId"], item["xref_id"]))): + if filerow["PubMed_ID"] == dbrow["PubMed_ID"]: + continue + + newpubmed = filerow["PubMed_ID"] + diff = diff + ({ + **dbrow, + "PubMed_ID": newpubmed, + "PublicationId": pubmedid2pubidmap.get(newpubmed)},) + + return diff diff --git a/uploader/publications/models.py b/uploader/publications/models.py new file mode 100644 index 0000000..b199991 --- /dev/null +++ b/uploader/publications/models.py @@ -0,0 +1,96 @@ +"""Module to handle persistence and retrieval of publication to/from MariaDB""" +import logging +from typing import Iterable, Optional + +from MySQLdb.cursors import DictCursor + +from gn_libs.mysqldb import Connection, debug_query + +logger = logging.getLogger(__name__) + + +def fetch_phenotype_publications( + conn: Connection, + ids: tuple[tuple[int, int], ...] +) -> tuple[dict, ...]: + """Fetch publication from database by ID.""" + paramstr = ",".join(["(%s, %s)"] * len(ids)) + query = ( + "SELECT " + "pxr.PhenotypeId, pxr.Id AS xref_id, pxr.PublicationId, pub.PubMed_ID " + "FROM PublishXRef AS pxr INNER JOIN Publication AS pub " + "ON pxr.PublicationId=pub.Id " + f"WHERE (pxr.PhenotypeId, pxr.Id) IN ({paramstr})") + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute(query, tuple(item for row in ids for item in row)) + return tuple(dict(row) for row in cursor.fetchall()) + + +def create_new_publications( + conn: Connection, + publications: tuple[dict, ...] +) -> tuple[dict, ...]: + if len(publications) > 0: + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.executemany( + ("INSERT INTO " + "Publication( " + "PubMed_ID, Abstract, Authors, Title, Journal, Volume, Pages, " + "Month, Year" + ") " + "VALUES(" + "%(pubmed_id)s, %(abstract)s, %(authors)s, %(title)s, " + "%(journal)s, %(volume)s, %(pages)s, %(month)s, %(year)s" + ") " + "RETURNING *"), + publications) + return tuple({ + **row, "publication_id": row["Id"] + } for row in cursor.fetchall()) + return tuple() + + +def update_publications(conn: Connection , publications: tuple[dict, ...]) -> tuple[dict, ...]: + """Update details for multiple publications""" + if len(publications) > 0: + with conn.cursor(cursorclass=DictCursor) as cursor: + logger.debug("UPDATING PUBLICATIONS: %s", publications) + cursor.executemany( + ("UPDATE Publication SET " + "PubMed_ID=%(pubmed_id)s, Abstract=%(abstract)s, " + "Authors=%(authors)s, Title=%(title)s, Journal=%(journal)s, " + "Volume=%(volume)s, Pages=%(pages)s, Month=%(month)s, " + "Year=%(year)s " + "WHERE Id=%(publication_id)s"), + publications) + debug_query(cursor, logger) + return publications + return tuple() + return tuple() + + +def fetch_publication_by_id(conn: Connection, publication_id: int) -> dict: + """Fetch a specific publication from the database.""" + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute("SELECT * FROM Publication WHERE Id=%s", + (publication_id,)) + _res = cursor.fetchone() + return dict(_res) if _res else {} + + +def fetch_publication_phenotypes( + conn: Connection, publication_id: int) -> Iterable[dict]: + """Fetch all phenotypes linked to this publication.""" + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute( + "SELECT pxr.Id AS xref_id, pxr.PublicationId, phe.* " + "FROM PublishXRef AS pxr INNER JOIN Phenotype AS phe " + "ON pxr.PhenotypeId=phe.Id " + "WHERE pxr.PublicationId=%s", + (publication_id,)) + while True: + row = cursor.fetchone() + if row: + yield row + else: + break diff --git a/uploader/publications/pubmed.py b/uploader/publications/pubmed.py new file mode 100644 index 0000000..ed9b652 --- /dev/null +++ b/uploader/publications/pubmed.py @@ -0,0 +1,103 @@ +"""Module to interact with NCBI's PubMed""" +import logging + +import requests +from lxml import etree + +logger = logging.getLogger(__name__) + + +def __pub_date__(pubdate: etree.Element): + pubyear = pubdate.find("Year") + pubmonth = pubdate.find("Month") + pubday = pubdate.find("Day") + return { + "year": pubyear.text if pubyear is not None else None, + "month": pubmonth.text if pubmonth is not None else None, + "day": pubday.text if pubday is not None else None + } + + +def __journal__(journal: etree.Element) -> dict: + volume = journal.find("JournalIssue/Volume") + issue = journal.find("JournalIssue/Issue") + return { + "volume": volume.text if volume is not None else None, + "issue": issue.text if issue is not None else None, + **__pub_date__(journal.find("JournalIssue/PubDate")), + "journal": journal.find("Title").text + } + +def __author__(author: etree.Element) -> str: + return "%s %s" % ( + author.find("LastName").text, + author.find("Initials").text) + + +def __pages__(pagination: etree.Element) -> str: + start = pagination.find("StartPage") + end = pagination.find("EndPage") + return (start.text + ( + f"-{end.text}" if end is not None else "" + )) if start is not None else "" + + +def __abstract__(article: etree.Element) -> str: + abstract = article.find("Abstract/AbstractText") + return abstract.text if abstract is not None else None + + +def __article__(pubmed_article: etree.Element) -> dict: + article = pubmed_article.find("MedlineCitation/Article") + return { + "pubmed_id": int(pubmed_article.find("MedlineCitation/PMID").text), + "title": article.find("ArticleTitle").text, + **__journal__(article.find("Journal")), + "abstract": __abstract__(article), + "pages": __pages__(article.find("Pagination")), + "authors": ", ".join(__author__(author) + for author in article.findall("AuthorList/Author")) + } + + +def __process_pubmed_publication_data__(text) -> tuple[dict, ...]: + """Process the data from PubMed into usable data.""" + doc = etree.XML(text) + articles = doc.xpath("//PubmedArticle") + logger.debug("Retrieved %s publications from NCBI", len(articles)) + return tuple(__article__(article) for article in articles) + +def fetch_publications(pubmed_ids: tuple[int, ...]) -> tuple[dict, ...]: + """Retrieve data on new publications from NCBI.""" + # See whether we can retrieve multiple publications in one go + # Parse data and save to DB + # Return PublicationId(s) for new publication(s). + if len(pubmed_ids) == 0: + logger.debug("There are no new PubMed IDs to fetch") + return tuple() + + logger.info("Fetching publications data for the following PubMed IDs: %s", + ", ".join((str(pid) for pid in pubmed_ids))) + + # Should we, perhaps, pass this in from a config variable? + uri = "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi" + try: + response = requests.get( + uri, + params={ + "db": "pubmed", + "retmode": "xml", + "id": ",".join(str(item) for item in pubmed_ids) + }) + + if response.status_code == 200: + return __process_pubmed_publication_data__(response.text) + + logger.error( + "Could not fetch the new publication from %s (status code: %s)", + uri, + response.status_code) + except requests.exceptions.ConnectionError: + logger.error("Could not find the domain %s", uri) + + return tuple() diff --git a/uploader/publications/views.py b/uploader/publications/views.py new file mode 100644 index 0000000..0608a35 --- /dev/null +++ b/uploader/publications/views.py @@ -0,0 +1,107 @@ +"""Endpoints for publications""" +import json + +from MySQLdb.cursors import DictCursor +from gn_libs.mysqldb import database_connection +from flask import ( + flash, + request, + url_for, + redirect, + Blueprint, + render_template, + current_app as app) + +from uploader.authorisation import require_login + +from .models import ( + fetch_publication_by_id, + create_new_publications, + fetch_publication_phenotypes) + +from .datatables import fetch_publications + +from gn_libs.debug import __pk__ + +pubbp = Blueprint("publications", __name__) + + +@pubbp.route("/", methods=["GET"]) +@require_login +def index(): + """Index page for publications.""" + with database_connection(app.config["SQL_URI"]) as conn: + return render_template("publications/index.html") + + +@pubbp.route("/list", methods=["GET"]) +@require_login +def list_publications(): + # request breakdown: + # https://datatables.net/manual/server-side + _page = int(request.args.get("draw")) + _length = int(request.args.get("length") or '-1') + _start = int(request.args.get("start") or '0') + _search = request.args["search[value]"] + with (database_connection(app.config["SQL_URI"]) as conn, + conn.cursor(cursorclass=DictCursor) as cursor): + _publications, _current_rows, _totalfiltered, _totalrows = fetch_publications( + conn, + _search, + offset=_start, + limit=_length) + + return json.dumps({ + "draw": _page, + "recordsTotal": _totalrows, + "recordsFiltered": _totalfiltered, + "publications": _publications, + "status": "success" + }) + + +@pubbp.route("/view/<int:publication_id>", methods=["GET"]) +@require_login +def view_publication(publication_id: int): + """View more details on a particular publication.""" + with database_connection(app.config["SQL_URI"]) as conn: + return render_template( + "publications/view-publication.html", + publication=fetch_publication_by_id(conn, publication_id), + linked_phenotypes=tuple(fetch_publication_phenotypes( + conn, publication_id))) + + +@pubbp.route("/create", methods=["GET", "POST"]) +@require_login +def create_publication(): + """Create a new publication.""" + if(request.method == "GET"): + return render_template("publications/create-publication.html") + form = request.form + authors = form.get("publication-authors").encode("utf8") + if authors is None or authors == "": + flash("The publication's author(s) MUST be provided!", "alert alert-danger") + return redirect(url_for("publications.create", **request.args)) + + with database_connection(app.config["SQL_URI"]) as conn: + publications = create_new_publications(conn, ({ + "pubmed_id": form.get("pubmed-id") or None, + "abstract": form.get("publication-abstract").encode("utf8") or None, + "authors": authors, + "title": form.get("publication-title").encode("utf8") or None, + "journal": form.get("publication-journal").encode("utf8") or None, + "volume": form.get("publication-volume").encode("utf8") or None, + "pages": form.get("publication-pages").encode("utf8") or None, + "month": (form.get("publication-month") or "").encode("utf8").capitalize() or None, + "year": form.get("publication-year").encode("utf8") or None + },)) + flash("New publication created!", "alert alert-success") + return redirect(url_for( + request.args.get("return_to") or "publications.view_publication", + publication_id=publications[0]["publication_id"], + **request.args)) + + flash("Publication creation failed!", "alert alert-danger") + app.logger.debug("Failed to create the new publication.", exc_info=True) + return redirect(url_for("publications.create_publication")) diff --git a/uploader/request_checks.py b/uploader/request_checks.py new file mode 100644 index 0000000..f1d8027 --- /dev/null +++ b/uploader/request_checks.py @@ -0,0 +1,75 @@ +"""Functions to perform common checks. + +These are useful for reusability, and hence maintainability of the code. +""" +from functools import wraps + +from gn_libs.mysqldb import database_connection +from flask import flash, url_for, redirect, current_app as app + +from uploader.species.models import species_by_id +from uploader.population.models import population_by_species_and_id + +def with_species(redirect_uri: str): + """Ensure the species actually exists.""" + def __decorator__(function): + @wraps(function) + def __with_species__(**kwargs): + try: + species_id = int(kwargs.get("species_id")) + if not bool(species_id): + flash("Expected species_id value to be present!", + "alert-danger") + return redirect(url_for(redirect_uri)) + with database_connection(app.config["SQL_URI"]) as conn: + species = species_by_id(conn, species_id) + if not bool(species): + flash("Could not find species with that ID", + "alert-danger") + return redirect(url_for(redirect_uri)) + except ValueError as _verr: + app.logger.debug( + "Exception converting value to integer: %s", + kwargs.get("species_id"), + exc_info=True) + flash("Expected an integer for 'species_id' value.", + "alert-danger") + return redirect(url_for(redirect_uri)) + return function(**{**kwargs, "species": species}) + return __with_species__ + return __decorator__ + + +def with_population(species_redirect_uri: str, redirect_uri: str): + """Ensure the population actually exists.""" + def __decorator__(function): + @wraps(function) + @with_species(redirect_uri=species_redirect_uri) + def __with_population__(**kwargs): + try: + species_id = int(kwargs["species_id"]) + population_id = int(kwargs.get("population_id")) + select_population_uri = redirect(url_for( + redirect_uri, species_id=species_id)) + if not bool(population_id): + flash("Expected population_id value to be present!", + "alert-danger") + return select_population_uri + with database_connection(app.config["SQL_URI"]) as conn: + population = population_by_species_and_id( + conn, species_id, population_id) + if not bool(population): + flash("Could not find population with that ID", + "alert-danger") + return select_population_uri + except ValueError as _verr: + app.logger.debug( + "Exception converting value to integer: %s", + kwargs.get("population_id"), + exc_info=True) + flash("Expected an integer for 'population_id' value.", + "alert-danger") + return select_population_uri + return function(**{**kwargs, "population": population}) + return __with_population__ + return __decorator__ diff --git a/uploader/route_utils.py b/uploader/route_utils.py new file mode 100644 index 0000000..ce718fb --- /dev/null +++ b/uploader/route_utils.py @@ -0,0 +1,42 @@ +"""Generic routing utilities.""" +from flask import flash, url_for, redirect, render_template, current_app as app + +from gn_libs.mysqldb import database_connection + +from uploader.population.models import (populations_by_species, + population_by_species_and_id) + +def generic_select_population( + # pylint: disable=[too-many-arguments, too-many-positional-arguments] + species: dict, + template: str, + population_id: str, + back_to: str, + forward_to: str, + activelink: str, + error_message: str = "No such population found!" +): + """Handles common flow for 'select population' step.""" + with database_connection(app.config["SQL_URI"]) as conn: + if not bool(population_id): + return render_template( + template, + species=species, + populations=populations_by_species(conn, species["SpeciesId"]), + activelink=activelink) + + if population_id == "CREATE-POPULATION": + return redirect(url_for( + "species.populations.create_population", + species_id=species["SpeciesId"], + return_to=forward_to)) + + population = population_by_species_and_id( + conn, species["SpeciesId"], int(population_id)) + if not bool(population): + flash(error_message, "alert-danger") + return redirect(url_for(back_to, species_id=species["SpeciesId"])) + + return redirect(url_for(forward_to, + species_id=species["SpeciesId"], + population_id=population["Id"])) diff --git a/uploader/samples.py b/uploader/samples.py deleted file mode 100644 index 7a80336..0000000 --- a/uploader/samples.py +++ /dev/null @@ -1,359 +0,0 @@ -"""Code regarding samples""" -import os -import sys -import csv -import uuid -from pathlib import Path -from typing import Iterator - -import MySQLdb as mdb -from redis import Redis -from MySQLdb.cursors import DictCursor -from flask import ( - flash, - request, - url_for, - redirect, - Blueprint, - render_template, - current_app as app) - -from functional_tools import take - -from uploader import jobs -from uploader.files import save_file -from uploader.authorisation import require_login -from uploader.input_validation import is_integer_input -from uploader.db_utils import ( - with_db_connection, - database_connection, - with_redis_connection) -from uploader.db import ( - species_by_id, - save_population, - population_by_id, - populations_by_species, - species as fetch_species) - -samples = Blueprint("samples", __name__) - -@samples.route("/upload/species", methods=["GET", "POST"]) -@require_login -def select_species(): - """Select the species.""" - if request.method == "GET": - return render_template("samples/select-species.html", - species=with_db_connection(fetch_species)) - - index_page = redirect(url_for("entry.upload_file")) - species_id = request.form.get("species_id") - if bool(species_id): - species_id = int(species_id) - species = with_db_connection( - lambda conn: species_by_id(conn, species_id)) - if bool(species): - return redirect(url_for( - "samples.select_population", species_id=species_id)) - flash("Invalid species selected!", "alert-error") - flash("You need to select a species", "alert-error") - return index_page - -@samples.route("/upload/species/<int:species_id>/create-population", - methods=["POST"]) -@require_login -def create_population(species_id: int): - """Create new grouping/population.""" - if not is_integer_input(species_id): - flash("You did not provide a valid species. Please select one to " - "continue.", - "alert-danger") - return redirect(url_for("samples.select_species")) - species = with_db_connection(lambda conn: species_by_id(conn, species_id)) - if not bool(species): - flash("Species with given ID was not found.", "alert-danger") - return redirect(url_for("samples.select_species")) - - species_page = redirect(url_for("samples.select_species"), code=307) - with database_connection(app.config["SQL_URI"]) as conn: - species = species_by_id(conn, species_id) - pop_name = request.form.get("inbredset_name", "").strip() - pop_fullname = request.form.get("inbredset_fullname", "").strip() - - if not bool(species): - flash("Invalid species!", "alert-error error-create-population") - return species_page - if (not bool(pop_name)) or (not bool(pop_fullname)): - flash("You *MUST* provide a grouping/population name", - "alert-error error-create-population") - return species_page - - pop = save_population(conn, { - "SpeciesId": species["SpeciesId"], - "Name": pop_name, - "InbredSetName": pop_fullname, - "FullName": pop_fullname, - "Family": request.form.get("inbredset_family") or None, - "Description": request.form.get("description") or None - }) - - flash("Grouping/Population created successfully.", "alert-success") - return redirect(url_for("samples.upload_samples", - species_id=species_id, - population_id=pop["population_id"])) - -@samples.route("/upload/species/<int:species_id>/population", - methods=["GET", "POST"]) -@require_login -def select_population(species_id: int): - """Select from existing groupings/populations.""" - if not is_integer_input(species_id): - flash("You did not provide a valid species. Please select one to " - "continue.", - "alert-danger") - return redirect(url_for("samples.select_species")) - species = with_db_connection(lambda conn: species_by_id(conn, species_id)) - if not bool(species): - flash("Species with given ID was not found.", "alert-danger") - return redirect(url_for("samples.select_species")) - - if request.method == "GET": - return render_template( - "samples/select-population.html", - species=species, - populations=with_db_connection( - lambda conn: populations_by_species(conn, species_id))) - - population_page = redirect(url_for( - "samples.select_population", species_id=species_id), code=307) - _population_id = request.form.get("inbredset_id") - if not is_integer_input(_population_id): - flash("You did not provide a valid population. Please select one to " - "continue.", - "alert-danger") - return population_page - population = with_db_connection( - lambda conn: population_by_id(conn, _population_id)) - if not bool(population): - flash("Invalid grouping/population!", - "alert-error error-select-population") - return population_page - - return redirect(url_for("samples.upload_samples", - species_id=species_id, - population_id=_population_id), - code=307) - -def read_samples_file(filepath, separator: str, firstlineheading: bool, **kwargs) -> Iterator[dict]: - """Read the samples file.""" - with open(filepath, "r", encoding="utf-8") as inputfile: - reader = csv.DictReader( - inputfile, - fieldnames=( - None if firstlineheading - else ("Name", "Name2", "Symbol", "Alias")), - delimiter=separator, - quotechar=kwargs.get("quotechar", '"')) - for row in reader: - yield row - -def save_samples_data(conn: mdb.Connection, - speciesid: int, - file_data: Iterator[dict]): - """Save the samples to DB.""" - data = ({**row, "SpeciesId": speciesid} for row in file_data) - total = 0 - with conn.cursor() as cursor: - while True: - batch = take(data, 5000) - if len(batch) == 0: - break - cursor.executemany( - "INSERT INTO Strain(Name, Name2, SpeciesId, Symbol, Alias) " - "VALUES(" - " %(Name)s, %(Name2)s, %(SpeciesId)s, %(Symbol)s, %(Alias)s" - ") ON DUPLICATE KEY UPDATE Name=Name", - batch) - total += len(batch) - print(f"\tSaved {total} samples total so far.") - -def cross_reference_samples(conn: mdb.Connection, - species_id: int, - population_id: int, - strain_names: Iterator[str]): - """Link samples to their population.""" - with conn.cursor(cursorclass=DictCursor) as cursor: - cursor.execute( - "SELECT MAX(OrderId) AS loid FROM StrainXRef WHERE InbredSetId=%s", - (population_id,)) - last_order_id = (cursor.fetchone()["loid"] or 10) - total = 0 - while True: - batch = take(strain_names, 5000) - if len(batch) == 0: - break - params_str = ", ".join(["%s"] * len(batch)) - ## This query is slow -- investigate. - cursor.execute( - "SELECT s.Id FROM Strain AS s LEFT JOIN StrainXRef AS sx " - "ON s.Id = sx.StrainId WHERE s.SpeciesId=%s AND s.Name IN " - f"({params_str}) AND sx.StrainId IS NULL", - (species_id,) + tuple(batch)) - strain_ids = (sid["Id"] for sid in cursor.fetchall()) - params = tuple({ - "pop_id": population_id, - "strain_id": strain_id, - "order_id": last_order_id + (order_id * 10), - "mapping": "N", - "pedigree": None - } for order_id, strain_id in enumerate(strain_ids, start=1)) - cursor.executemany( - "INSERT INTO StrainXRef( " - " InbredSetId, StrainId, OrderId, Used_for_mapping, PedigreeStatus" - ")" - "VALUES (" - " %(pop_id)s, %(strain_id)s, %(order_id)s, %(mapping)s, " - " %(pedigree)s" - ")", - params) - last_order_id += (len(params) * 10) - total += len(batch) - print(f"\t{total} total samples cross-referenced to the population " - "so far.") - -def build_sample_upload_job(# pylint: disable=[too-many-arguments] - speciesid: int, - populationid: int, - samplesfile: Path, - separator: str, - firstlineheading: bool, - quotechar: str): - """Define the async command to run the actual samples data upload.""" - return [ - sys.executable, "-m", "scripts.insert_samples", app.config["SQL_URI"], - str(speciesid), str(populationid), str(samplesfile.absolute()), - separator, f"--redisuri={app.config['REDIS_URL']}", - f"--quotechar={quotechar}" - ] + (["--firstlineheading"] if firstlineheading else []) - -@samples.route("/upload/species/<int:species_id>/populations/<int:population_id>/samples", - methods=["GET", "POST"]) -@require_login -def upload_samples(species_id: int, population_id: int):#pylint: disable=[too-many-return-statements] - """Upload the samples.""" - samples_uploads_page = redirect(url_for("samples.upload_samples", - species_id=species_id, - population_id=population_id)) - if not is_integer_input(species_id): - flash("You did not provide a valid species. Please select one to " - "continue.", - "alert-danger") - return redirect(url_for("samples.select_species")) - species = with_db_connection(lambda conn: species_by_id(conn, species_id)) - if not bool(species): - flash("Species with given ID was not found.", "alert-danger") - return redirect(url_for("samples.select_species")) - - if not is_integer_input(population_id): - flash("You did not provide a valid population. Please select one " - "to continue.", - "alert-danger") - return redirect(url_for("samples.select_population", - species_id=species_id), - code=307) - population = with_db_connection( - lambda conn: population_by_id(conn, int(population_id))) - if not bool(population): - flash("Invalid grouping/population!", "alert-error") - return redirect(url_for("samples.select_population", - species_id=species_id), - code=307) - - if request.method == "GET" or request.files.get("samples_file") is None: - return render_template("samples/upload-samples.html", - species=species, - population=population) - - try: - samples_file = save_file(request.files["samples_file"], - Path(app.config["UPLOAD_FOLDER"])) - except AssertionError: - flash("You need to provide a file with the samples data.", - "alert-error") - return samples_uploads_page - - firstlineheading = (request.form.get("first_line_heading") == "on") - - separator = request.form.get("separator", ",") - if separator == "other": - separator = request.form.get("other_separator", ",") - if not bool(separator): - flash("You need to provide a separator character.", "alert-error") - return samples_uploads_page - - quotechar = (request.form.get("field_delimiter", '"') or '"') - - redisuri = app.config["REDIS_URL"] - with Redis.from_url(redisuri, decode_responses=True) as rconn: - the_job = jobs.launch_job( - jobs.initialise_job( - rconn, - jobs.jobsnamespace(), - str(uuid.uuid4()), - build_sample_upload_job( - species["SpeciesId"], - population["InbredSetId"], - samples_file, - separator, - firstlineheading, - quotechar), - "samples_upload", - app.config["JOBS_TTL_SECONDS"], - {"job_name": f"Samples Upload: {samples_file.name}"}), - redisuri, - f"{app.config['UPLOAD_FOLDER']}/job_errors") - return redirect(url_for( - "samples.upload_status", job_id=the_job["jobid"])) - -@samples.route("/upload/status/<uuid:job_id>", methods=["GET"]) -def upload_status(job_id: uuid.UUID): - """Check on the status of a samples upload job.""" - job = with_redis_connection(lambda rconn: jobs.job( - rconn, jobs.jobsnamespace(), job_id)) - if job: - status = job["status"] - if status == "success": - return render_template("samples/upload-success.html", job=job) - - if status == "error": - return redirect(url_for("samples.upload_failure", job_id=job_id)) - - error_filename = Path(jobs.error_filename( - job_id, f"{app.config['UPLOAD_FOLDER']}/job_errors")) - if error_filename.exists(): - stat = os.stat(error_filename) - if stat.st_size > 0: - return redirect(url_for( - "samples.upload_failure", job_id=job_id)) - - return render_template( - "samples/upload-progress.html", - job=job) # maybe also handle this? - - return render_template("no_such_job.html", job_id=job_id), 400 - -@samples.route("/upload/failure/<uuid:job_id>", methods=["GET"]) -def upload_failure(job_id: uuid.UUID): - """Display the errors of the samples upload failure.""" - job = with_redis_connection(lambda rconn: jobs.job( - rconn, jobs.jobsnamespace(), job_id)) - if not bool(job): - return render_template("no_such_job.html", job_id=job_id), 400 - - error_filename = Path(jobs.error_filename( - job_id, f"{app.config['UPLOAD_FOLDER']}/job_errors")) - if error_filename.exists(): - stat = os.stat(error_filename) - if stat.st_size > 0: - return render_template("worker_failure.html", job_id=job_id) - - return render_template("samples/upload-failure.html", job=job) diff --git a/uploader/samples/__init__.py b/uploader/samples/__init__.py new file mode 100644 index 0000000..1bd6d2d --- /dev/null +++ b/uploader/samples/__init__.py @@ -0,0 +1 @@ +"""Samples package. Handle samples uploads and editing.""" diff --git a/uploader/samples/models.py b/uploader/samples/models.py new file mode 100644 index 0000000..b419d61 --- /dev/null +++ b/uploader/samples/models.py @@ -0,0 +1,104 @@ +"""Functions for handling samples.""" +import csv +from typing import Iterator + +import MySQLdb as mdb +from MySQLdb.cursors import DictCursor + +from functional_tools import take + +def samples_by_species_and_population( + conn: mdb.Connection, + species_id: int, + population_id: int +) -> tuple[dict, ...]: + """Fetch the samples by their species and population.""" + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute( + "SELECT InbredSet.InbredSetId, Strain.* FROM InbredSet " + "INNER JOIN StrainXRef ON InbredSet.InbredSetId=StrainXRef.InbredSetId " + "INNER JOIN Strain ON StrainXRef.StrainId=Strain.Id " + "WHERE Strain.SpeciesId=%(species_id)s " + "AND InbredSet.InbredSetId=%(population_id)s", + {"species_id": species_id, "population_id": population_id}) + return tuple(cursor.fetchall()) + + +def read_samples_file(filepath, separator: str, firstlineheading: bool, **kwargs) -> Iterator[dict]: + """Read the samples file.""" + with open(filepath, "r", encoding="utf-8") as inputfile: + reader = csv.DictReader( + inputfile, + fieldnames=( + None if firstlineheading + else ("Name", "Name2", "Symbol", "Alias")), + delimiter=separator, + quotechar=kwargs.get("quotechar", '"')) + for row in reader: + yield row + + +def save_samples_data(conn: mdb.Connection, + speciesid: int, + file_data: Iterator[dict]): + """Save the samples to DB.""" + data = ({**row, "SpeciesId": speciesid} for row in file_data) + total = 0 + with conn.cursor() as cursor: + while True: + batch = take(data, 5000) + if len(batch) == 0: + break + cursor.executemany( + "INSERT INTO Strain(Name, Name2, SpeciesId, Symbol, Alias) " + "VALUES(" + " %(Name)s, %(Name2)s, %(SpeciesId)s, %(Symbol)s, %(Alias)s" + ") ON DUPLICATE KEY UPDATE Name=Name", + batch) + total += len(batch) + print(f"\tSaved {total} samples total so far.") + + +def cross_reference_samples(conn: mdb.Connection, + species_id: int, + population_id: int, + strain_names: Iterator[str]): + """Link samples to their population.""" + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute( + "SELECT MAX(OrderId) AS loid FROM StrainXRef WHERE InbredSetId=%s", + (population_id,)) + last_order_id = (cursor.fetchone()["loid"] or 10) + total = 0 + while True: + batch = take(strain_names, 5000) + if len(batch) == 0: + break + params_str = ", ".join(["%s"] * len(batch)) + ## This query is slow -- investigate. + cursor.execute( + "SELECT s.Id FROM Strain AS s LEFT JOIN StrainXRef AS sx " + "ON s.Id = sx.StrainId WHERE s.SpeciesId=%s AND s.Name IN " + f"({params_str}) AND sx.StrainId IS NULL", + (species_id,) + tuple(batch)) + strain_ids = (sid["Id"] for sid in cursor.fetchall()) + params = tuple({ + "pop_id": population_id, + "strain_id": strain_id, + "order_id": last_order_id + (order_id * 10), + "mapping": "N", + "pedigree": None + } for order_id, strain_id in enumerate(strain_ids, start=1)) + cursor.executemany( + "INSERT INTO StrainXRef( " + " InbredSetId, StrainId, OrderId, Used_for_mapping, PedigreeStatus" + ")" + "VALUES (" + " %(pop_id)s, %(strain_id)s, %(order_id)s, %(mapping)s, " + " %(pedigree)s" + ")", + params) + last_order_id += (len(params) * 10) + total += len(batch) + print(f"\t{total} total samples cross-referenced to the population " + "so far.") diff --git a/uploader/samples/views.py b/uploader/samples/views.py new file mode 100644 index 0000000..c0adb88 --- /dev/null +++ b/uploader/samples/views.py @@ -0,0 +1,271 @@ +"""Code regarding samples""" +import os +import sys +import uuid +from pathlib import Path + +from redis import Redis +from flask import (flash, + request, + url_for, + redirect, + Blueprint, + current_app as app) + +from uploader import jobs +from uploader.files import save_file +from uploader.ui import make_template_renderer +from uploader.authorisation import require_login +from uploader.input_validation import is_integer_input +from uploader.population.models import population_by_id +from uploader.route_utils import generic_select_population +from uploader.datautils import safe_int, enumerate_sequence +from uploader.species.models import all_species, species_by_id +from uploader.request_checks import with_species, with_population +from uploader.db_utils import (with_db_connection, + database_connection, + with_redis_connection) + +from .models import samples_by_species_and_population + +samplesbp = Blueprint("samples", __name__) +render_template = make_template_renderer("samples") + +@samplesbp.route("/samples", methods=["GET"]) +@require_login +def index(): + """Direct entry-point for uploading/handling the samples.""" + with database_connection(app.config["SQL_URI"]) as conn: + if not bool(request.args.get("species_id")): + return render_template( + "samples/index.html", + species=all_species(conn), + activelink="samples") + + species_id = request.args.get("species_id") + if species_id == "CREATE-SPECIES": + return redirect(url_for( + "species.create_species", + return_to="species.populations.samples.select_population")) + + species = species_by_id(conn, request.args.get("species_id")) + if not bool(species): + flash("No such species!", "alert-danger") + return redirect(url_for("species.populations.samples.index")) + return redirect(url_for("species.populations.samples.select_population", + species_id=species["SpeciesId"])) + + +@samplesbp.route("<int:species_id>/samples/select-population", methods=["GET"]) +@require_login +@with_species(redirect_uri="species.populations.samples.index") +def select_population(species: dict, **kwargs):# pylint: disable=[unused-argument] + """Select the population to use for the samples.""" + return generic_select_population( + species, + "samples/select-population.html", + request.args.get("population_id") or "", + "species.populations.samples.select_population", + "species.populations.samples.list_samples", + "samples", + "Population not found!") + +@samplesbp.route("<int:species_id>/populations/<int:population_id>/samples") +@require_login +@with_population( + species_redirect_uri="species.populations.samples.index", + redirect_uri="species.populations.samples.select_population") +def list_samples(species: dict, population: dict, **kwargs):# pylint: disable=[unused-argument] + """ + List the samples in a particular population and give the ability to upload + new ones. + """ + with database_connection(app.config["SQL_URI"]) as conn: + all_samples = enumerate_sequence(samples_by_species_and_population( + conn, species["SpeciesId"], population["Id"])) + total_samples = len(all_samples) + offset = max(safe_int(request.args.get("from") or 0), 0) + count = int(request.args.get("count") or 20) + return render_template("samples/list-samples.html", + species=species, + population=population, + samples=all_samples[offset:offset+count], + offset=offset, + count=count, + total_samples=total_samples, + activelink="list-samples") + + +def build_sample_upload_job(# pylint: disable=[too-many-arguments] + speciesid: int, + populationid: int, + samplesfile: Path, + separator: str, + firstlineheading: bool, + quotechar: str): + """Define the async command to run the actual samples data upload.""" + return [ + sys.executable, "-m", "scripts.insert_samples", app.config["SQL_URI"], + str(speciesid), str(populationid), str(samplesfile.absolute()), + separator, f"--redisuri={app.config['REDIS_URL']}", + f"--quotechar={quotechar}" + ] + (["--firstlineheading"] if firstlineheading else []) + + +@samplesbp.route("<int:species_id>/populations/<int:population_id>/upload-samples", + methods=["GET", "POST"]) +@require_login +def upload_samples(species_id: int, population_id: int):#pylint: disable=[too-many-return-statements] + """Upload the samples.""" + samples_uploads_page = redirect(url_for( + "species.populations.samples.upload_samples", + species_id=species_id, + population_id=population_id)) + if not is_integer_input(species_id): + flash("You did not provide a valid species. Please select one to " + "continue.", + "alert-danger") + return redirect(url_for("expression-data.samples.select_species")) + species = with_db_connection(lambda conn: species_by_id(conn, species_id)) + if not bool(species): + flash("Species with given ID was not found.", "alert-danger") + return redirect(url_for("expression-data.samples.select_species")) + + if not is_integer_input(population_id): + flash("You did not provide a valid population. Please select one " + "to continue.", + "alert-danger") + return redirect(url_for("species.populations.samples.select_population", + species_id=species_id), + code=307) + population = with_db_connection( + lambda conn: population_by_id(conn, int(population_id))) + if not bool(population): + flash("Invalid grouping/population!", "alert-error") + return redirect(url_for("species.populations.samples.select_population", + species_id=species_id), + code=307) + + if request.method == "GET" or request.files.get("samples_file") is None: + return render_template("samples/upload-samples.html", + species=species, + population=population) + + try: + samples_file = save_file(request.files["samples_file"], + Path(app.config["UPLOAD_FOLDER"])) + except AssertionError: + flash("You need to provide a file with the samples data.", + "alert-error") + return samples_uploads_page + + firstlineheading = (request.form.get("first_line_heading") == "on") + + separator = request.form.get("separator", ",") + if separator == "other": + separator = request.form.get("other_separator", ",") + if not bool(separator): + flash("You need to provide a separator character.", "alert-error") + return samples_uploads_page + + quotechar = (request.form.get("field_delimiter", '"') or '"') + + redisuri = app.config["REDIS_URL"] + with Redis.from_url(redisuri, decode_responses=True) as rconn: + #TODO: Add a QC step here — what do we check? + # 1. Does any sample in the uploaded file exist within the database? + # If yes, what is/are its/their species and population? + # 2. If yes 1. above, provide error with notes on which species and + # populations already own the samples. + the_job = jobs.launch_job( + jobs.initialise_job( + rconn, + jobs.jobsnamespace(), + str(uuid.uuid4()), + build_sample_upload_job( + species["SpeciesId"], + population["InbredSetId"], + samples_file, + separator, + firstlineheading, + quotechar), + "samples_upload", + app.config["JOBS_TTL_SECONDS"], + {"job_name": f"Samples Upload: {samples_file.name}"}), + redisuri, + f"{app.config['UPLOAD_FOLDER']}/job_errors") + return redirect(url_for( + "species.populations.samples.upload_status", + species_id=species_id, + population_id=population_id, + job_id=the_job["jobid"])) + + +@samplesbp.route("<int:species_id>/populations/<int:population_id>/" + "upload-samples/status/<uuid:job_id>", + methods=["GET"]) +@require_login +@with_population(species_redirect_uri="species.populations.samples.index", + redirect_uri="species.populations.samples.select_population") +def upload_status(species: dict, population: dict, job_id: uuid.UUID, **kwargs):# pylint: disable=[unused-argument] + """Check on the status of a samples upload job.""" + job = with_redis_connection(lambda rconn: jobs.job( + rconn, jobs.jobsnamespace(), job_id)) + if job: + status = job["status"] + if status == "success": + return render_template("samples/upload-success.html", + job=job, + species=species, + population=population,) + + if status == "error": + return redirect(url_for( + "species.populations.samples.upload_failure", + species_id=species["SpeciesId"], + population_id=population["Id"], + job_id=job_id)) + + error_filename = Path(jobs.error_filename( + job_id, f"{app.config['UPLOAD_FOLDER']}/job_errors")) + if error_filename.exists(): + stat = os.stat(error_filename) + if stat.st_size > 0: + return redirect(url_for( + "samples.upload_failure", job_id=job_id)) + + return render_template("samples/upload-progress.html", + species=species, + population=population, + job=job) # maybe also handle this? + + return render_template("no_such_job.html", + job_id=job_id, + species=species, + population=population), 400 + + +@samplesbp.route("<int:species_id>/populations/<int:population_id>/" + "upload-samples/failure/<uuid:job_id>", + methods=["GET"]) +@require_login +@with_population(species_redirect_uri="species.populations.samples.index", + redirect_uri="species.populations.samples.select_population") +def upload_failure(species: dict, population: dict, job_id: uuid.UUID, **kwargs): + """Display the errors of the samples upload failure.""" + job = with_redis_connection(lambda rconn: jobs.job( + rconn, jobs.jobsnamespace(), job_id)) + if not bool(job): + return render_template("no_such_job.html", job_id=job_id), 400 + + error_filename = Path(jobs.error_filename( + job_id, f"{app.config['UPLOAD_FOLDER']}/job_errors")) + if error_filename.exists(): + stat = os.stat(error_filename) + if stat.st_size > 0: + return render_template("worker_failure.html", job_id=job_id) + + return render_template("samples/upload-failure.html", + species=species, + population=population, + job=job) diff --git a/uploader/session.py b/uploader/session.py index 8b72bce..5af5827 100644 --- a/uploader/session.py +++ b/uploader/session.py @@ -1,7 +1,9 @@ """Deal with user sessions""" from uuid import UUID, uuid4 +from datetime import datetime from typing import Any, Optional, TypedDict +from authlib.jose import KeySet from flask import request, session from pymonad.either import Left, Right, Either @@ -75,12 +77,15 @@ def set_user_token(token: str) -> SessionInfo: """Set the user's token.""" info = session_info() return save_session_info({ - **info, "user": {**info["user"], "token": Right(token)}})#type: ignore[misc] + **info, + "user": {**info["user"], "token": Right(token), "logged_in": True} + })#type: ignore[misc] def set_user_details(userdets: UserDetails) -> SessionInfo: """Set the user details information""" - return save_session_info({**session_info(), "user": userdets})#type: ignore[misc] + info = session_info() + return save_session_info({**info, "user": {**info["user"], **userdets}})#type: ignore[misc] def user_details() -> UserDetails: """Retrieve user details.""" @@ -89,3 +94,28 @@ def user_details() -> UserDetails: def user_token() -> Either: """Retrieve the user token.""" return session_info()["user"]["token"] + + +def set_auth_server_jwks(keyset: KeySet) -> KeySet: + """Update the JSON Web Keys in the session.""" + save_session_info({ + **session_info(),# type: ignore[misc] + "auth_server_jwks": { + "last-updated": datetime.now().timestamp(), + "jwks": keyset.as_dict() + } + }) + return keyset + + +def toggle_token_refreshing(): + """Toggle the state of the token_refreshing variable.""" + _session = session_info() + return save_session_info({ + **_session, + "token_refreshing": not _session.get("token_refreshing", False)}) + + +def is_token_refreshing(): + """Returns whether the token is being refreshed or not.""" + return session_info().get("token_refreshing", False) diff --git a/uploader/species/__init__.py b/uploader/species/__init__.py new file mode 100644 index 0000000..83f2165 --- /dev/null +++ b/uploader/species/__init__.py @@ -0,0 +1,2 @@ +"""Package to handle creation and management of species.""" +from .views import speciesbp diff --git a/uploader/species/models.py b/uploader/species/models.py new file mode 100644 index 0000000..db53d48 --- /dev/null +++ b/uploader/species/models.py @@ -0,0 +1,154 @@ +"""Database functions for species.""" +import math +from typing import Optional +from functools import reduce + +import MySQLdb as mdb +from MySQLdb.cursors import DictCursor + +def all_species(conn: mdb.Connection) -> tuple: + "Retrieve the species from the database." + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute( + "SELECT Id AS SpeciesId, SpeciesName, LOWER(Name) AS Name, " + "MenuName, FullName, TaxonomyId, Family, FamilyOrderId, OrderId " + "FROM Species ORDER BY FamilyOrderId ASC, OrderID ASC") + return tuple(cursor.fetchall()) + + return tuple() + +def order_species_by_family(species: tuple[dict, ...]) -> list: + """Order the species by their family""" + def __family_order_id__(item): + orderid = item["FamilyOrderId"] + return math.inf if orderid is None else orderid + def __order__(ordered, current): + _key = (__family_order_id__(current), current["Family"]) + return { + **ordered, + _key: ordered.get(_key, tuple()) + (current,) + } + ordered = reduce(__order__, species, {})# type: ignore[var-annotated] + return sorted(tuple(ordered.items()), key=lambda item: item[0][0]) + + +def species_by_id(conn: mdb.Connection, speciesid) -> dict: + "Retrieve the species from the database by id." + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute( + "SELECT Id AS SpeciesId, SpeciesName, LOWER(Name) AS Name, " + "MenuName, FullName, TaxonomyId, Family, FamilyOrderId, OrderId " + "FROM Species WHERE SpeciesId=%s", + (speciesid,)) + return cursor.fetchone() + + +def save_species(conn: mdb.Connection, + common_name: str, + scientific_name: str, + family: str, + taxon_id: Optional[str] = None) -> dict: + """ + Save a new species to the database. + + Parameters + ---------- + conn: A connection to the MariaDB database. + taxon_id: The taxonomy identifier for the new species. + common_name: The species' common name. + scientific_name; The species' scientific name. + """ + genus, *species_parts = scientific_name.split(" ") + species_name: str = " ".join(species_parts) + families = species_families(conn) + with conn.cursor() as cursor: + cursor.execute("SELECT MAX(OrderId) FROM Species") + species = { + "common_name": common_name, + "common_name_lower": common_name.lower(), + "menu_name": f"{common_name} ({genus[0]}. {species_name.lower()})", + "scientific_name": scientific_name, + "family": family, + "family_order": families.get(family, 999999), + "taxon_id": taxon_id, + "species_order": cursor.fetchone()[0] + 5 + } + cursor.execute( + "INSERT INTO Species(" + "SpeciesName, Name, MenuName, FullName, Family, FamilyOrderId, " + "TaxonomyId, OrderId" + ") VALUES (" + "%(common_name)s, %(common_name_lower)s, %(menu_name)s, " + "%(scientific_name)s, %(family)s, %(family_order)s, %(taxon_id)s, " + "%(species_order)s" + ")", + species) + species_id = cursor.lastrowid + cursor.execute("UPDATE Species SET SpeciesId=%s WHERE Id=%s", + (species_id, species_id)) + return { + **species, + "species_id": species_id + } + + +def update_species(# pylint: disable=[too-many-arguments] + conn: mdb.Connection, + species_id: int, + common_name: str, + scientific_name: str, + family: str, + family_order: int, + species_order: int +): + """Update a species' details. + + Parameters + ---------- + conn: A connection to the MariaDB database. + species_id: The species identifier + + Key-Word Arguments + ------------------ + common_name: A layman's name for the species + scientific_name: A binomial nomenclature name for the species + family: The grouping under which the species falls + family_order: The ordering for the "family" above + species_order: The ordering of this species in relation to others + """ + with conn.cursor(cursorclass=DictCursor) as cursor: + genus, *species_parts = scientific_name.split(" ") + species_name = " ".join(species_parts) + species = { + "species_id": species_id, + "common_name": common_name, + "common_name_lower": common_name.lower(), + "menu_name": f"{common_name} ({genus[0]}. {species_name.lower()})", + "scientific_name": scientific_name, + "family": family, + "family_order": family_order, + "species_order": species_order + } + cursor.execute( + "UPDATE Species SET " + "SpeciesName=%(common_name)s, " + "Name=%(common_name_lower)s, " + "MenuName=%(menu_name)s, " + "FullName=%(scientific_name)s, " + "Family=%(family)s, " + "FamilyOrderId=%(family_order)s, " + "OrderId=%(species_order)s " + "WHERE Id=%(species_id)s", + species) + + +def species_families(conn: mdb.Connection) -> dict: + """Retrieve the families under which species are grouped.""" + with conn.cursor(cursorclass=DictCursor) as cursor: + cursor.execute( + "SELECT DISTINCT(Family), FamilyOrderId FROM Species " + "WHERE Family IS NOT NULL") + return { + fam["Family"]: fam["FamilyOrderId"] + for fam in cursor.fetchall() + } diff --git a/uploader/species/views.py b/uploader/species/views.py new file mode 100644 index 0000000..cea2f68 --- /dev/null +++ b/uploader/species/views.py @@ -0,0 +1,211 @@ +"""Endpoints handling species.""" +from markupsafe import escape +from pymonad.either import Left, Right, Either +from gn_libs.mysqldb import database_connection +from flask import (flash, + request, + url_for, + redirect, + Blueprint, + current_app as app) + +from uploader.population import popbp +from uploader.platforms import platformsbp +from uploader.ui import make_template_renderer +from uploader.oauth2.client import oauth2_get, oauth2_post +from uploader.authorisation import require_login, require_token +from uploader.datautils import order_by_family, enumerate_sequence + +from .models import (all_species, + save_species, + species_by_id, + update_species, + species_families) + + +speciesbp = Blueprint("species", __name__) +speciesbp.register_blueprint(popbp, url_prefix="/") +speciesbp.register_blueprint(platformsbp, url_prefix="/") +render_template = make_template_renderer("species") + + +@speciesbp.route("/", methods=["GET"]) +@require_login +def list_species(): + """List and display all the species in the database.""" + with database_connection(app.config["SQL_URI"]) as conn: + return render_template("species/list-species.html", + allspecies=enumerate_sequence(all_species(conn))) + +@speciesbp.route("/<int:species_id>", methods=["GET"]) +@require_login +def view_species(species_id: int): + """View details of a particular species and menus to act upon it.""" + with database_connection(app.config["SQL_URI"]) as conn: + species = species_by_id(conn, species_id) + if bool(species): + return render_template("species/view-species.html", + species=species, + activelink="view-species") + flash("Could not find a species with the given identifier.", + "alert-danger") + return redirect(url_for("species.view_species")) + +@speciesbp.route("/create", methods=["GET", "POST"]) +@require_login +def create_species(): + """Create a new species.""" + # We can use uniprot's API to fetch the details with something like + # https://rest.uniprot.org/taxonomy/<taxonID> e.g. + # https://rest.uniprot.org/taxonomy/6239 + with (database_connection(app.config["SQL_URI"]) as conn, + conn.cursor() as cursor): + if request.method == "GET": + return render_template("species/create-species.html", + families=species_families(conn), + return_to=( + request.args.get("return_to") or ""), + activelink="create-species") + + error = False + taxon_id = request.form.get("species_taxonomy_id", "").strip() or None + + common_name = request.form.get("common_name", "").strip() + if not bool(common_name): + flash("The common species name MUST be provided.", "alert-danger") + error = True + + scientific_name = request.form.get("scientific_name", "").strip() + if not bool(scientific_name): + flash("The species' scientific name MUST be provided.", + "alert-danger") + error = True + + parts = tuple(name.strip() for name in scientific_name.split(" ")) + if (len(parts) != 2 and len(parts) != 3) or not all(bool(name) for name in parts): + flash("The scientific name you provided is invalid.", "alert-danger") + error = True + + cursor.execute( + "SELECT * FROM Species WHERE FullName=%s", (scientific_name,)) + res = cursor.fetchone() + if bool(res): + flash("A species already exists with the provided scientific name.", + "alert-danger") + error = True + + family = request.form.get("species_family", "").strip() + if not bool(family): + flash("The species' family MUST be selected.", "alert-danger") + error = True + + if bool(taxon_id): + cursor.execute( + "SELECT * FROM Species WHERE TaxonomyId=%s", (taxon_id,)) + res = cursor.fetchone() + if bool(res): + flash("A species already exists with the provided scientific name.", + "alert-danger") + error = True + + if error: + return redirect(url_for("species.create_species", + common_name=common_name, + scientific_name=scientific_name, + taxon_id=taxon_id)) + + species = save_species( + conn, common_name, scientific_name, family, taxon_id) + flash( + f"You have successfully added species " + f"'{escape(species['scientific_name'])} " + f"({escape(species['common_name'])})'.", + "alert-success") + + return_to = request.form.get("return_to").strip() + if return_to: + return redirect(url_for(return_to, species_id=species["species_id"])) + return redirect(url_for("species.view_species", species_id=species["species_id"])) + + +@speciesbp.route("/<int:species_id>/edit-extra", methods=["GET", "POST"]) +@require_login +@require_token +#def edit_species(species_id: int): +def edit_species_extra(token: dict, species_id: int):# pylint: disable=[unused-argument] + """Edit a species' details. + + Parameters + ---------- + token: A JWT token used for authorisation. + species_id: An identifier for the species being edited. + """ + def __failure__(res): + app.logger.debug( + "There was an error in the attempt to edit the species: %s", res) + flash(res, "alert-danger") + return redirect(url_for("species.view_species", species_id=species_id)) + + def __system_resource_uuid__(resources) -> Either: + sys_res = [ + resource for resource in resources + if resource["resource_category"]["resource_category_key"] == "system" + ] + if len(sys_res) != 1: + return Left("Could not find/identify a valid system resource.") + return Right(sys_res[0]["resource_id"]) + + def __check_privileges__(authorisations): + if len(authorisations.items()) != 1: + return Left("Got authorisations for more than a single resource!") + + auths = tuple(authorisations.items())[0][1] + authorised = "system:species:edit-extra-info" in tuple( + privilege["privilege_id"] + for role in auths["roles"] + for privilege in role["privileges"]) + if authorised: + return Right(authorised) + return Left("You are not authorised to edit species extra details.") + + with database_connection(app.config["SQL_URI"]) as conn: + species = species_by_id(conn, species_id) + all_the_species = all_species(conn) + families = species_families(conn) + family_order = tuple( + item[0] for item in order_by_family(all_the_species) + if item[0][1] is not None) + if bool(species) and request.method == "GET": + return oauth2_get("auth/user/resources").then( + __system_resource_uuid__ + ).then( + lambda resource_id: oauth2_post( + "auth/resource/authorisation", + json={"resource-ids": [resource_id]}) + ).then(__check_privileges__).then( + lambda authorisations: render_template( + "species/edit-species.html", + species=species, + families=families, + family_order=family_order, + max_order_id = max( + row["OrderId"] for row in all_the_species + if row["OrderId"] is not None), + activelink="edit-species") + ).either(__failure__, lambda res: res) + + if bool(species) and request.method == "POST": + update_species(conn, + species_id, + request.form["species_name"], + request.form["species_fullname"], + request.form["species_family"], + int(request.form["species_familyorderid"]), + int(request.form["species_orderid"])) + flash("Updated species successfully.", "alert-success") + return redirect(url_for("species.edit_species_extra", + species_id=species_id)) + + flash("Species with the given identifier was not found!", + "alert-danger") + return redirect(url_for("species.list_species")) diff --git a/uploader/static/css/styles.css b/uploader/static/css/styles.css index a88c229..df50dec 100644 --- a/uploader/static/css/styles.css +++ b/uploader/static/css/styles.css @@ -1,7 +1,187 @@ +* { + box-sizing: border-box; +} + +body { + margin: 0.7em; + display: grid; + grid-template-columns: 2fr 8fr; + grid-gap: 20px; + + font-family: "Helvetica Neue", Helvetica, Arial, sans-serif; + font-style: normal; + font-size: 20px; +} + +#header { + /* Place it in the parent element */ + grid-column-start: 1; + grid-column-end: 3; + + /* Define layout for the children elements */ + display: grid; + grid-template-columns: 8fr 2fr; + + /* Content styling */ + background-color: #336699; + color: #FFFFFF; + border-radius: 3px; + min-height: 30px; +} + +#header #header-text { + /* Place it in the parent element */ + grid-column-start: 1; + grid-column-end: 2; + + /* Content styling */ + padding-left: 1em; +} + +#header #header-nav { + /* Place it in the parent element */ + grid-column-start: 2; + grid-column-end: 3; +} + +#header #header-nav .nav li a { + /* Content styling */ + color: #FFFFFF; + background: #4477AA; + border: solid 5px #336699; + border-radius: 5px; + font-size: 0.7em; + text-align: center; + padding: 1px 7px; +} + +#nav-sidebar { + /* Place it in the parent element */ + grid-column-start: 1; + grid-column-end: 2; +} + +#nav-sidebar .nav li a:hover { + border-radius: 0.5em; +} + +#nav-sidebar .nav .activemenu { + border-style: solid; + border-radius: 0.5em; + border-color: #AAAAAA; + background-color: #EFEFEF; +} + +#main { + /* Place it in the parent element */ + grid-column-start: 2; + grid-column-end: 3; + + /* Define layout for the children elements */ + display: grid; + grid-template-columns: 1fr; + grid-template-rows: 4em 100%; + grid-gap: 1em; +} + +#main #pagetitle { + /* Place it in the parent element */ + grid-column-start: 1; + grid-column-end: 3; + + /* Content-styling */ + border-radius: 3px; + background-color: #88BBEE; +} + +#main #pagetitle .title { + font-size: 1.4em; + text-transform: capitalize; + padding-left: 0.5em; +} + +@media screen and (max-width: 20in) { + #main #all-content { + /* Place it in the parent element */ + grid-column-start: 1; + grid-column-end: 3; + + /* Define layout for the children elements */ + max-width: 80%; + } + + #sidebar-content { + display: none; + } +} + +@media screen and (min-width: 20.1in) { + #main #all-content { + /* Place it in the parent element */ + grid-column-start: 1; + grid-column-end: 3; + + /* Define layout for the children elements */ + display: grid; + grid-template-columns: 7fr 3fr; + grid-gap: 1.5em; + } +} + +#main #all-content .row { + margin: 0 2px; +} + +#main #all-content #main-content { + background: #FFFFFF; + max-width: 950px; +} + +#pagetitle .breadcrumb { + background: none; + text-transform: capitalize; + font-size: 0.75em; +} + +#pagetitle .breadcrumb .active a { + color: #333333; +} + +#pagetitle .breadcrumb a { + color: #666666; +} + .heading { + border-bottom: solid #EEBB88; text-transform: capitalize; } -label { +.subheading { + padding: 1em 0 0.1em 0.5em; + border-bottom: solid #88BBEE; text-transform: capitalize; } + +input[type="search"] { + border-radius: 5px; +} + +.btn { + text-transform: Capitalize; +} + +table.dataTable thead th, table.dataTable tfoot th{ + border-right: 1px solid white; + color: white; + background-color: #369 !important; +} + +table.dataTable tbody tr.selected td { + background-color: #ffee99 !important; +} + +.form-group { + margin-bottom: 2em; + padding-bottom: 0.2em; + border-bottom: solid gray 1px; +} diff --git a/uploader/static/js/datatables.js b/uploader/static/js/datatables.js new file mode 100644 index 0000000..82fd696 --- /dev/null +++ b/uploader/static/js/datatables.js @@ -0,0 +1,69 @@ +/** Handlers for events in datatables **/ + +var addTableLength = (menuList, lengthToAdd, dataLength) => { + if(dataLength >= lengthToAdd) { + newList = structuredClone(menuList);//menuList.slice(0, menuList.length); // shallow copy + newList.push(lengthToAdd); + return newList; + } + return menuList; +}; + +var defaultLengthMenu = (data) => { + menuList = [] + var lengths = [10, 25, 50, 100, 1000, data.length]; + lengths.forEach((len) => { + menuList = addTableLength(menuList, len, data.length); + }); + return menuList; +}; + +var buildDataTable = (tableId, data = [], columns = [], userSettings = {}) => { + var defaultSettings = { + responsive: true, + layout: { + topStart: null, + topEnd: null, + bottomStart: null, + bottomEnd: null, + }, + select: true, + lengthMenu: defaultLengthMenu(data), + language: { + processing: "Processing… Please wait.", + loadingRecords: "Loading table data… Please wait.", + lengthMenu: "", + info: "" + }, + data: data, + columns: columns, + drawCallback: (settings) => { + $(this[0]).find("tbody tr").each((idx, row) => { + var arow = $(row); + var checkboxOrRadio = arow.find(".chk-row-select"); + if (checkboxOrRadio) { + if (arow.hasClass("selected")) { + checkboxOrRadio.prop("checked", true); + } else { + checkboxOrRadio.prop("checked", false); + } + } + }); + } + } + var theDataTable = $(tableId).DataTable({ + ...defaultSettings, + ...userSettings + }); + theDataTable.on("select", (event, datatable, type, cell, originalEvent) => { + datatable.rows({selected: true}).nodes().each((node, index) => { + $(node).find(".chk-row-select").prop("checked", true) + }); + }); + theDataTable.on("deselect", (event, datatable, type, cell, originalEvent) => { + datatable.rows({selected: false}).nodes().each((node, index) => { + $(node).find(".chk-row-select").prop("checked", false) + }); + }); + return theDataTable; +}; diff --git a/uploader/static/js/debug.js b/uploader/static/js/debug.js new file mode 100644 index 0000000..eb01209 --- /dev/null +++ b/uploader/static/js/debug.js @@ -0,0 +1,40 @@ +/** + * The entire purpose of this function is for use to debug values inline + * without changing the flow of the code too much. + * + * This **MUST** be a non-arrow function to allow access to the `arguments` + * object. + * + * This function expects at least one argument. + * + * If more than one argument is provided, then: + * a) the last argument is considered the value, and will be returned + * b) all other arguments will be converted to string and output + * + * If only one argument is provided, it is considered the value, and will be + * returned. + * + * Zero arguments is an error condition. + **/ +function __pk__(val) { + /* Handle zero arguments */ + if (arguments.length < 1) { + throw new Error("Invalid arguments: Expected at least one argument."); + } + + msg = "/********** DEBUG **********/"; + if (arguments.length > 1) { + msg = Array.from( + arguments + ).slice( + 0, + arguments.length - 1 + ).map((val) => { + return String(val); + }).join("; ") + } + + value = arguments[arguments.length - 1]; + console.debug("/********** " + msg + " **********/", value); + return value; +} diff --git a/uploader/static/js/files.js b/uploader/static/js/files.js new file mode 100644 index 0000000..0bde6f7 --- /dev/null +++ b/uploader/static/js/files.js @@ -0,0 +1,118 @@ +var readFirstNLines = (thefile, count, process_content_fns) => { + var reader = new FileReader(); + if(typeof thefile !== "undefined" && thefile !== null) { + reader.addEventListener("load", (event) => { + var content = event + .target + .result + .split("\n") + .slice(0, count) + .map((line) => {return line.trim("\r");}); + process_content_fns.forEach((fn) => {fn(content);}); + }); + reader.readAsText(thefile); + } +}; +var read_first_n_lines = readFirstNLines; + + +var readBinaryFile = (file) => { + return new Promise((resolve, reject) => { + var _reader = new FileReader(); + _reader.onload = (event) => {resolve(_reader.result);}; + _reader.readAsArrayBuffer(file); + }); +}; + + +var Uint8ArrayToHex = (arr) => { + var toHex = (val) => { + _hex = val.toString(16); + if(_hex.length < 2) { + return "0" + val; + } + return _hex; + }; + _hexstr = "" + arr.forEach((val) => {_hexstr += toHex(val)}); + return _hexstr +}; + + +var computeFileChecksum = (file) => { + return readBinaryFile(file) + .then((content) => { + return window.crypto.subtle.digest( + "SHA-256", new Uint8Array(content)); + }).then((digest) => { + return Uint8ArrayToHex(new Uint8Array(digest)) + }); +}; + + +var defaultResumableHandler = (event) => { + throw new Error("Please provide a valid event handler!"); +}; + +var addHandler = (resumable, handlername, handler) => { + if(resumable.support) { + resumable.on(handlername, (handler || defaultResumableHandler)); + } + return resumable; +}; + + +var makeResumableHandler = (handlername) => { + return (resumable, handler) => { + return addHandler(resumable, handlername, handler); + }; +}; + + +var fileSuccessHandler = makeResumableHandler("fileSuccess"); +var fileProgressHandler = makeResumableHandler("fileProgress"); +var fileAddedHandler = makeResumableHandler("fileAdded"); +var filesAddedHandler = makeResumableHandler("filesAdded"); +var filesRetryHandler = makeResumableHandler("filesRetry"); +var filesErrorHandler = makeResumableHandler("filesError"); +var uploadStartHandler = makeResumableHandler("uploadStart"); +var completeHandler = makeResumableHandler("complete"); +var progressHandler = makeResumableHandler("progress"); +var errorHandler = makeResumableHandler("error"); + + +var markResumableDragAndDropElement = (resumable, fileinput, droparea, browsebutton) => { + if(resumable.support) { + //Hide file input element and display drag&drop UI + add_class(fileinput, "visually-hidden"); + remove_class(droparea, "visually-hidden"); + + // Define UI elements for browse and drag&drop + resumable.assignDrop(droparea); + resumable.assignBrowse(browsebutton); + } + + return resumable; +}; + + +var makeResumableElement = (targeturi, fileinput, droparea, uploadbutton, filetype) => { + var resumable = Resumable({ + target: targeturi, + fileType: filetype, + maxFiles: 1, + forceChunkSize: true, + generateUniqueIdentifier: (file, event) => { + return computeFileChecksum(file).then((checksum) => { + var _relativePath = (file.webkitRelativePath + || file.relativePath + || file.fileName + || file.name); + return checksum + "-" + _relativePath.replace( + /[^a-zA-Z0-9_-]/img, ""); + }); + } + }); + + return resumable; +}; diff --git a/uploader/static/js/populations.js b/uploader/static/js/populations.js new file mode 100644 index 0000000..be1231f --- /dev/null +++ b/uploader/static/js/populations.js @@ -0,0 +1,21 @@ +$(() => { + var populationsDataTable = buildDataTable( + "#tbl-select-population", + JSON.parse( + $("#tbl-select-population").attr("data-populations-list")), + [ + { + data: (apopulation) => { + return `<input type="radio" name="population_id"` + + `id="rdo_population_id_${apopulation.InbredSetId}" ` + + `value="${apopulation.InbredSetId}" ` + + `class="chk-row-select">`; + } + }, + { + data: (apopulation) => { + return `${apopulation.FullName} (${apopulation.InbredSetName})`; + } + } + ]); +}); diff --git a/uploader/static/js/pubmed.js b/uploader/static/js/pubmed.js new file mode 100644 index 0000000..9afd4c3 --- /dev/null +++ b/uploader/static/js/pubmed.js @@ -0,0 +1,113 @@ +var extract_details = (pubmed_id, details) => { + var months = { + "jan": "January", + "feb": "February", + "mar": "March", + "apr": "April", + "may": "May", + "jun": "June", + "jul": "July", + "aug": "August", + "sep": "September", + "oct": "October", + "nov": "November", + "dec": "December" + }; + var _date = details[pubmed_id].pubdate.split(" "); + return { + "authors": details[pubmed_id].authors.map((authobj) => { + return authobj.name; + }), + "title": details[pubmed_id].title, + "journal": details[pubmed_id].fulljournalname, + "volume": details[pubmed_id].volume, + "pages": details[pubmed_id].pages, + "month": _date.length > 1 ? months[_date[1].toLowerCase()] : "jan", + "year": _date[0], + }; +}; + +var update_publication_details = (details) => { + Object.entries(details).forEach((entry) => {; + switch(entry[0]) { + case "authors": + $("#txt-publication-authors").val(entry[1].join(", ")); + break; + case "month": + $("#select-publication-month") + .children("option") + .each((index, child) => { + console.debug(entry[1].toLowerCase()); + child.selected = child.value == entry[1].toLowerCase(); + }); + default: + $("#txt-publication-" + entry[0]).val(entry[1]); + break; + } + }); +}; + +var fetch_publication_abstract = (pubmed_id, pub_details) => { + $.ajax("https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi", + { + "method": "GET", + "data": { + "db": "pubmed", + "id": pubmed_id, + "rettype": "abstract", + "retmode": "xml" + }, + "success": (data, textStatus, jqXHR) => { + update_publication_details({ + ...pub_details, + ...{ + "abstract": Array.from(data + .getElementsByTagName( + "Abstract")[0] + .children) + .map((elt) => {return elt.textContent.trim();}) + .join("\r\n") + }}); + }, + "error": (jqXHR, textStatus, errorThrown) => {}, + "complete": (jqXHR, textStatus) => {}, + "dataType": "xml" + }); +}; + +var fetch_publication_details = (pubmed_id, complete_thunks) => { + error_display = $("#search-pubmed-id-error"); + error_display.text(""); + add_class(error_display, "visually-hidden"); + $.ajax("https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi", + { + "method": "GET", + "data": {"db": "pubmed", "id": pubmed_id, "format": "json"}, + "success": (data, textStatus, jqXHR) => { + // process and update publication details + hasError = ( + Object.hasOwn(data, "error") || + Object.hasOwn(data.result[pubmed_id], "error")); + if(hasError) { + error_display.text( + "There was an error fetching a publication with " + + "the given PubMed ID! The error received " + + "was: '" + ( + data.error || + data.result[pubmed_id].error) + + "'. Please check ID you provided and try " + + "again."); + remove_class(error_display, "visually-hidden"); + } else { + fetch_publication_abstract( + pubmed_id, + extract_details(pubmed_id, data.result)); + } + }, + "error": (jqXHR, textStatus, errorThrown) => {}, + "complete": () => { + complete_thunks.forEach((thunk) => {thunk()}); + }, + "dataType": "json" + }); +}; diff --git a/uploader/static/js/species.js b/uploader/static/js/species.js new file mode 100644 index 0000000..9ea3017 --- /dev/null +++ b/uploader/static/js/species.js @@ -0,0 +1,20 @@ +$(() => { + var speciesDataTable = buildDataTable( + "#tbl-select-species", + JSON.parse( + $("#tbl-select-species").attr("data-species-list")), + [ + { + data: (aspecies) => { + return `<input type="radio" name="species_id"` + + `id="rdo_species_id_${aspecies.SpeciesId}" ` + + `value="${aspecies.SpeciesId}" class="chk-row-select">`; + } + }, + { + data: (aspecies) => { + return `${aspecies.FullName} (${aspecies.SpeciesName})`; + } + } + ]); +}); diff --git a/uploader/static/js/utils.js b/uploader/static/js/utils.js index 045dd47..1b31661 100644 --- a/uploader/static/js/utils.js +++ b/uploader/static/js/utils.js @@ -8,3 +8,30 @@ function trigger_change_event(element) { evt = new Event("change"); element.dispatchEvent(evt); } + + +var remove_class = (element, classvalue) => { + new_classes = (element.attr("class") || "").split(" ").map((val) => { + return val.trim(); + }).filter((val) => { + return ((val !== classvalue) && + (val !== "")) + }).join(" "); + + if(new_classes === "") { + element.removeAttr("class"); + } else { + element.attr("class", new_classes); + } +}; + + +var add_class = (element, classvalue) => { + remove_class(element, classvalue); + element.attr("class", (element.attr("class") || "") + " " + classvalue); +}; + +$(".not-implemented").click((event) => { + event.preventDefault(); + alert("This feature is not implemented yet. Please bear with us."); +}); diff --git a/uploader/templates/base.html b/uploader/templates/base.html index ee60fea..3c0d0d4 100644 --- a/uploader/templates/base.html +++ b/uploader/templates/base.html @@ -1,62 +1,161 @@ <!DOCTYPE html> <html lang="en"> + <head> + <meta charset="UTF-8" /> <meta application-name="GeneNetwork Quality-Control Application" /> <meta name="viewport" content="width=device-width, initial-scale=1.0" /> {%block extrameta%}{%endblock%} - <title>GN Uploader: {%block title%}{%endblock%}</title> + <title>Data Upload and Quality Control: {%block title%}{%endblock%}</title> <link rel="stylesheet" type="text/css" href="{{url_for('base.bootstrap', filename='css/bootstrap.min.css')}}" /> <link rel="stylesheet" type="text/css" - href="{{url_for('base.bootstrap', - filename='css/bootstrap-theme.min.css')}}" /> - - - <link rel="shortcut icon" type="image/png" sizes="64x64" - href="{{url_for('static', filename='images/CITGLogo.png')}}" /> - - <link rel="stylesheet" type="text/css" href="/static/css/custom-bootstrap.css" /> + href="{{url_for('base.datatables', + filename='css/dataTables.bootstrap5.min.css')}}" /> <link rel="stylesheet" type="text/css" href="/static/css/styles.css" /> {%block css%}{%endblock%} + </head> <body> - <div class="navbar navbar-inverse navbar-static-top pull-left" - role="navigation" - style="width: 100%;min-width: 850px;white-space: nowrap;"> - <div class="container-fluid" style="width: 100%"> - <ul class="nav navbar-nav"> - <li><a href="/" style="font-weight: bold">GN Uploader</a></li> - <li> - <a href="{{gn2server_uri()}}">GeneNetwork</a> - </li> - </ul> - <ul class="nav navbar-nav" style="margin-left: 2em;"> + <header id="header"> + <span id="header-text">GeneNetwork</span> + <nav id="header-nav"> + <ul class="nav justify-content-end"> <li> {%if user_logged_in()%} <a href="{{url_for('oauth2.logout')}}" - title="Log out of the system">Log Out</a> + title="Log out of the system"> + <span class="glyphicon glyphicon-user"></span> + {{user_email()}} Sign Out</a> {%else%} <a href="{{authserver_authorise_uri()}}" - title="Log in to the system">Log In</a> + title="Log in to the system">Sign In</a> {%endif%} </li> </ul> + </nav> + </header> + + <aside id="nav-sidebar"> + <ul class="nav flex-column"> + <li {%if activemenu=="home"%}class="activemenu"{%endif%}> + <a href="/" >Home</a></li> + <li {%if activemenu=="publications"%}class="activemenu"{%endif%}> + <a href="{{url_for('publications.index')}}" + title="View and manage publications.">Publications</a></li> + <li {%if activemenu=="species"%}class="activemenu"{%endif%}> + <a href="{{url_for('species.list_species')}}" + title="View and manage species information.">Species</a></li> + <li {%if activemenu=="platforms"%}class="activemenu"{%endif%}> + <a href="{{url_for('species.platforms.index')}}" + title="View and manage species platforms.">Sequencing Platforms</a></li> + <li {%if activemenu=="populations"%}class="activemenu"{%endif%}> + <a href="{{url_for('species.populations.index')}}" + title="View and manage species populations.">Populations</a></li> + <li {%if activemenu=="samples"%}class="activemenu"{%endif%}> + <a href="{{url_for('species.populations.samples.index')}}" + title="Upload population samples.">Samples</a></li> + <li {%if activemenu=="genotypes"%}class="activemenu"{%endif%}> + <a href="{{url_for('species.populations.genotypes.index')}}" + title="Upload Genotype data.">Genotype Data</a></li> + <!-- + TODO: Maybe include menus here for managing studies and dataset or + maybe have the studies/datasets managed under their respective + sections, e.g. "Publish*" studies/datasets under the "Phenotypes" + section, "ProbeSet*" studies/datasets under the "Expression Data" + sections, etc. + --> + <li {%if activemenu=="phenotypes"%}class="activemenu"{%endif%}> + <a href="{{url_for('species.populations.phenotypes.index')}}" + title="Upload phenotype data.">Phenotype Data</a></li> + <!-- + <li {%if activemenu=="expression-data"%}class="activemenu"{%endif%}> + <a href="{{url_for('species.populations.expression-data.index')}}" + title="Upload expression data." + class="not-implemented">Expression Data</a></li> + <li {%if activemenu=="individuals"%}class="activemenu"{%endif%}> + <a href="#" + class="not-implemented" + title="Upload individual data.">Individual Data</a></li> + <li {%if activemenu=="rna-seq"%}class="activemenu"{%endif%}> + <a href="#" + class="not-implemented" + title="Upload RNA-Seq data.">RNA-Seq Data</a></li> + <li {%if activemenu=="async-jobs"%}class="activemenu"{%endif%}> + <a href="#" + class="not-implemented" + title="View and manage the backgroud jobs you have running"> + Background Jobs</a></li> + --> + </ul> + </aside> + + <main id="main" class="main"> + + <div id="pagetitle" class="pagetitle"> + <span class="title">Data Upload and Quality Control: {%block pagetitle%}{%endblock%}</span> + <!-- + <nav> + <ol class="breadcrumb"> + <li {%if activelink is not defined or activelink=="home"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('base.index')}}">Home</a> + </li> + {%block lvl1_breadcrumbs%}{%endblock%} + </ol> + </nav> + --> </div> - </div> - <div class="container"> - {%block contents%}{%endblock%} - </div> + <div id="all-content"> + <div id="main-content"> + {%block contents%}{%endblock%} + </div> + <div id="sidebar-content"> + {%block sidebarcontents%}{%endblock%} + </div> + </div> + </main> + + + <!-- + Core dependencies + --> <script src="{{url_for('base.jquery', filename='jquery.min.js')}}"></script> <script src="{{url_for('base.bootstrap', filename='js/bootstrap.min.js')}}"></script> + + <!-- + DataTables dependencies + --> + <script type="text/javascript" + src="{{url_for('base.datatables', + filename='js/dataTables.min.js')}}"></script> + <script type="text/javascript" + src="{{url_for('base.datatables_extensions', + filename='scroller/js/dataTables.scroller.min.js')}}"></script> + <script type="text/javascript" + src="{{url_for('base.datatables_extensions', + filename='buttons/js/dataTables.buttons.min.js')}}"></script> + <script type="text/javascript" + src="{{url_for('base.datatables_extensions', + filename='select/js/dataTables.select.min.js')}}"></script> + + <!-- + local dependencies + --> + <script type="text/javascript" src="/static/js/utils.js"></script> + <script type="text/javascript" src="/static/js/datatables.js"></script> {%block javascript%}{%endblock%} </body> </html> diff --git a/uploader/templates/cli-output.html b/uploader/templates/cli-output.html index 33fb73b..64b1a9a 100644 --- a/uploader/templates/cli-output.html +++ b/uploader/templates/cli-output.html @@ -1,7 +1,7 @@ {%macro cli_output(job, stream)%} -<h4>{{stream | upper}} Output</h4> -<div class="cli-output"> +<h4 class="subheading">{{stream | upper}} Output</h4> +<div class="cli-output" style="max-height: 10em; overflow: auto;"> <pre>{{job.get(stream, "")}}</pre> </div> diff --git a/uploader/templates/expression-data/base.html b/uploader/templates/expression-data/base.html new file mode 100644 index 0000000..d63fd7e --- /dev/null +++ b/uploader/templates/expression-data/base.html @@ -0,0 +1,13 @@ +{%extends "populations/base.html"%} + +{%block lvl3_breadcrumbs%} +<li {%if activelink=="expression-data"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.expression-data.index')}}"> + Expression Data</a> +</li> +{%block lvl4_breadcrumbs%}{%endblock%} +{%endblock%} diff --git a/uploader/templates/data_review.html b/uploader/templates/expression-data/data-review.html index b7528fd..c985b03 100644 --- a/uploader/templates/data_review.html +++ b/uploader/templates/expression-data/data-review.html @@ -26,7 +26,7 @@ <small class="text-muted"> If you encounter an error saying your sample(s)/case(s) do not exist in the GeneNetwork database, then you will have to use the - <a href="{{url_for('samples.select_species')}}" + <a href="{{url_for('species.populations.samples.index')}}" title="Upload samples/cases feature">Upload Samples/Cases</a> option on this system to upload them. </small> @@ -70,8 +70,8 @@ column</li> <li>The values of each field <strong>ARE NOT</strong> quoted.</li> <li>Here is an - <a href="https://gitlab.com/fredmanglis/gnqc_py/-/blob/main/tests/test_data/no_data_errors.tsv"> - example file</a> with a single data row.</li> + <a href="https://gitlab.com/fredmanglis/gnqc_py/-/blob/main/tests/test_data/no_data_errors.tsv" + target="_blank">example file</a> with a single data row.</li> </ul> </li> <li>.txt files: Content has the same format as .tsv file above</li> diff --git a/uploader/templates/expression-data/index.html b/uploader/templates/expression-data/index.html new file mode 100644 index 0000000..9ba3582 --- /dev/null +++ b/uploader/templates/expression-data/index.html @@ -0,0 +1,33 @@ +{%extends "expression-data/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "species/macro-select-species.html" import select_species_form%} + +{%block title%}Expression Data{%endblock%} + +{%block pagetitle%}Expression Data{%endblock%} + +{%block breadcrumb%} +<li class="breadcrumb-item"> + <a href="{{url_for('base.index')}}">Home</a> +</li> +<li class="breadcrumb-item active"> + <a href="{{url_for('species.populations.expression-data.index')}}" + title="Upload expression data."> + Expression Data</a> +</li> +{%endblock%} + +{%block contents%} +<div class="row"> + <h2 class="heading">Expression Data</h2> + {{flash_all_messages()}} + + <p>This section allows you to enter the expression data for your experiment. + You will need to select the species that your data concerns below.</p> +</div> + +<div class="row"> + {{select_species_form(url_for("species.populations.expression-data.index"), + species)}} +</div> +{%endblock%} diff --git a/uploader/templates/job_progress.html b/uploader/templates/expression-data/job-progress.html index 1af0763..ef264e1 100644 --- a/uploader/templates/job_progress.html +++ b/uploader/templates/expression-data/job-progress.html @@ -1,5 +1,6 @@ {%extends "base.html"%} {%from "errors_display.html" import errors_display%} +{%from "populations/macro-display-population-card.html" import display_population_card%} {%block extrameta%} <meta http-equiv="refresh" content="5"> @@ -11,7 +12,9 @@ <h1 class="heading">{{job_name}}</h2> <div class="row"> - <form action="{{url_for('parse.abort')}}" method="POST"> + <form action="{{url_for('species.populations.expression-data.abort', + species_id=species.SpeciesId, + population_id=population.Id)}}" method="POST"> <legend class="heading">Status</legend> <div class="form-group"> <label for="job_status" class="form-label">status:</label> @@ -38,3 +41,7 @@ </div> {%endblock%} + +{%block sidebarcontents%} +{{display_population_card(species, population)}} +{%endblock%} diff --git a/uploader/templates/no_such_job.html b/uploader/templates/expression-data/no-such-job.html index 42a2d48..d22c429 100644 --- a/uploader/templates/no_such_job.html +++ b/uploader/templates/expression-data/no-such-job.html @@ -1,7 +1,8 @@ {%extends "base.html"%} {%block extrameta%} -<meta http-equiv="refresh" content="5;url={{url_for('entry.upload_file')}}"> +<meta http-equiv="refresh" + content="5;url={{url_for('species.populations.expression-data.index.upload_file')}}"> {%endblock%} {%block title%}No Such Job{%endblock%} diff --git a/uploader/templates/parse_failure.html b/uploader/templates/expression-data/parse-failure.html index 31f6be8..31f6be8 100644 --- a/uploader/templates/parse_failure.html +++ b/uploader/templates/expression-data/parse-failure.html diff --git a/uploader/templates/expression-data/parse-results.html b/uploader/templates/expression-data/parse-results.html new file mode 100644 index 0000000..03a23e2 --- /dev/null +++ b/uploader/templates/expression-data/parse-results.html @@ -0,0 +1,39 @@ +{%extends "base.html"%} +{%from "errors_display.html" import errors_display%} +{%from "populations/macro-display-population-card.html" import display_population_card%} + +{%block title%}Parse Results{%endblock%} + +{%block contents%} + +<div class="row"> + <h2 class="heading">{{job_name}}: parse results</h2> + + {%if user_aborted%} + <span class="alert-warning">Job aborted by the user</span> + {%endif%} + + {{errors_display(errors, "No errors found in the file", "We found the following errors", True)}} + + {%if errors | length == 0 and not user_aborted %} + <form method="post" action="{{url_for('dbinsert.select_platform')}}"> + <input type="hidden" name="job_id" value="{{job_id}}" /> + <input type="submit" value="update database" class="btn btn-primary" /> + </form> + {%endif%} + + {%if errors | length > 0 or user_aborted %} + <br /> + <a href="{{url_for('species.populations.expression-data.upload_file', + species_id=species.SpeciesId, + population_id=population.Id)}}" + title="Back to index page." + class="btn btn-primary">Go back</a> + + {%endif%} +</div> +{%endblock%} + +{%block sidebarcontents%} +{{display_population_card(species, population)}} +{%endblock%} diff --git a/uploader/templates/expression-data/select-file.html b/uploader/templates/expression-data/select-file.html new file mode 100644 index 0000000..4ca461e --- /dev/null +++ b/uploader/templates/expression-data/select-file.html @@ -0,0 +1,115 @@ +{%extends "expression-data/base.html"%} +{%from "flash_messages.html" import flash_messages%} +{%from "upload_progress_indicator.html" import upload_progress_indicator%} +{%from "populations/macro-display-population-card.html" import display_population_card%} + +{%block title%}Expression Data — Upload Data{%endblock%} + +{%block pagetitle%}Expression Data — Upload Data{%endblock%} + +{%block contents%} +{{upload_progress_indicator()}} + +<div class="row"> + <h2 class="heading">Upload Expression Data</h2> + + <p>This feature enables you to upload expression data. It expects the data to + be in <strong>tab-separated values (TSV)</strong> files. The data should be + a simple matrix of <em>phenotype × sample</em>, i.e. The first column is a + list of the <em>phenotypes</em> and the first row is a list of + <em>samples/cases</em>.</p> + + <p>If you haven't done so please go to this page to learn the requirements for + file formats and helpful suggestions to enter your data in a fast and easy + way.</p> + + <ol> + <li><strong>PLEASE REVIEW YOUR DATA.</strong>Make sure your data complies + with our system requirements. ( + <a href="{{url_for('species.populations.expression-data.data_review')}}#data-concerns" + title="Details for the data expectations.">Help</a> + )</li> + <li><strong>UPLOAD YOUR DATA FOR DATA VERIFICATION.</strong> We accept + <strong>.csv</strong>, <strong>.txt</strong> and <strong>.zip</strong> + files (<a href="{{url_for('species.populations.expression-data.data_review')}}#file-types" + title="Details for the data expectations.">Help</a>)</li> + </ol> +</div> + +<div class="row"> + <form action="{{url_for( + 'species.populations.expression-data.upload_file', + species_id=species.SpeciesId, + population_id=population.Id)}}" + method="POST" + enctype="multipart/form-data" + id="frm-upload-expression-data"> + {{flash_messages("error-expr-data")}} + + <div class="form-group"> + <legend class="heading">File Type</legend> + + <div class="radio"> + <label for="filetype_average" class="form-check-label"> + <input type="radio" name="filetype" value="average" id="filetype_average" + required="required" class="form-check-input" /> + Average</label> + <p class="form-text text-muted"> + <small>The averages data …</small></p> + </div> + + <div class="radio"> + <label for="filetype_standard_error" class="form-check-label"> + <input type="radio" name="filetype" value="standard-error" + id="filetype_standard_error" required="required" + class="form-check-input" /> + Standard Error + </label> + <p class="form-text text-muted"> + <small>The standard errors computed from the averages …</small></p> + </div> + </div> + + <div class="form-group"> + <span id="no-file-error" class="alert-danger" style="display: none;"> + No file selected + </span> + <label for="file_upload" class="form-label">Select File</label> + <input type="file" name="qc_text_file" id="file_upload" + accept="text/plain, text/tab-separated-values, application/zip" + class="form-control"/> + <p class="form-text text-muted"> + <small>Select the file to upload.</small></p> + </div> + + <button type="submit" + class="btn btn-primary" + data-toggle="modal" + data-target="#upload-progress-indicator">upload file</button> + </form> +</div> +{%endblock%} + +{%block sidebarcontents%} +{{display_population_card(species, population)}} +{%endblock%} + +{%block javascript%} +<script type="text/javascript" src="/static/js/upload_progress.js"></script> +<script type="text/javascript"> + function setup_formdata(form) { + var formdata = new FormData(); + formdata.append( + "qc_text_file", + form.querySelector("input[type='file']").files[0]); + formdata.append( + "filetype", + selected_filetype( + Array.from(form.querySelectorAll("input[type='radio']")))); + return formdata; + } + + setup_upload_handlers( + "frm-upload-expression-data", make_data_uploader(setup_formdata)); +</script> +{%endblock%} diff --git a/uploader/templates/expression-data/select-population.html b/uploader/templates/expression-data/select-population.html new file mode 100644 index 0000000..8555e27 --- /dev/null +++ b/uploader/templates/expression-data/select-population.html @@ -0,0 +1,29 @@ +{%extends "expression-data/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "species/macro-display-species-card.html" import display_species_card%} +{%from "populations/macro-select-population.html" import select_population_form%} + +{%block title%}Expression Data{%endblock%} + +{%block pagetitle%}Expression Data{%endblock%} + + +{%block contents%} +{{flash_all_messages()}} + +<div class="row"> + <p>You have selected the species. Now you need to select the population that + the expression data belongs to.</p> +</div> + +<div class="row"> + {{select_population_form(url_for( + "species.populations.expression-data.select_population", + species_id=species.SpeciesId), + populations)}} +</div> +{%endblock%} + +{%block sidebarcontents%} +{{display_species_card(species)}} +{%endblock%} diff --git a/uploader/templates/genotypes/base.html b/uploader/templates/genotypes/base.html new file mode 100644 index 0000000..7d61312 --- /dev/null +++ b/uploader/templates/genotypes/base.html @@ -0,0 +1,23 @@ +{%extends "populations/base.html"%} + +{%block lvl3_breadcrumbs%} +<li {%if activelink=="genotypes"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + {%if population is mapping%} + <a href="{{url_for('species.populations.genotypes.list_genotypes', + species_id=species.SpeciesId, + population_id=population.Id)}}"> + {%if dataset is defined and dataset is mapping%} + {{dataset.Name}} + {%else%} + Genotypes + {%endif%}</a> + {%else%} + <a href="{{url_for('species.populations.genotypes.index')}}">Genotypes</a> + {%endif%} +</li> +{%block lvl4_breadcrumbs%}{%endblock%} +{%endblock%} diff --git a/uploader/templates/genotypes/create-dataset.html b/uploader/templates/genotypes/create-dataset.html new file mode 100644 index 0000000..10331c1 --- /dev/null +++ b/uploader/templates/genotypes/create-dataset.html @@ -0,0 +1,82 @@ +{%extends "genotypes/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "populations/macro-display-population-card.html" import display_population_card%} + +{%block title%}Genotypes — Create Dataset{%endblock%} + +{%block pagetitle%}Genotypes — Create Dataset{%endblock%} + +{%block lvl4_breadcrumbs%} +<li {%if activelink=="create-dataset"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.genotypes.create_dataset', + species_id=species.SpeciesId, + population_id=population.Id)}}">Create Dataset</a> +</li> +{%endblock%} + +{%block contents%} +{{flash_all_messages()}} + +<div class="row"> + <form id="frm-geno-create-dataset" + method="POST" + action="{{url_for('species.populations.genotypes.create_dataset', + species_id=species.SpeciesId, + population_id=population.Id)}}"> + <legend>Create a new Genotype Dataset</legend> + + <div class="form-group"> + <label for="txt-geno-dataset-name" class="form-label">Name</label> + <input type="text" + id="txt-geno-dataset-name" + name="geno-dataset-name" + required="required" + class="form-control" /> + <small class="form-text text-muted"> + <p>This is a short representative, but constrained name for the genotype + dataset.<br /> + The field will only accept letters ('A-Za-z'), numbers (0-9), hyphens + and underscores. Any other character will cause the name to be + rejected.</p></small> + </div> + + <div class="form-group"> + <label for="txt-geno-dataset-fullname" class="form-label">Full Name</label> + <input type="text" + id="txt-geno-dataset-fullname" + name="geno-dataset-fullname" + required="required" + class="form-control" /> + <small class="form-text text-muted"> + <p>This is a longer, more descriptive name for your dataset.</p></small> + </div> + + <div class="form-group"> + <label for="txt-geno-dataset-shortname" + class="form-label">Short Name</label> + <input type="text" + id="txt-geno-dataset-shortname" + name="geno-dataset-shortname" + class="form-control" /> + <small class="form-text text-muted"> + <p>A short name for your dataset. If you leave this field blank, the + short name will be set to the same value as the + "<strong>Name</strong>" field above.</p></small> + </div> + + <div class="form-group"> + <input type="submit" + class="btn btn-primary" + value="create dataset" /> + </div> + </form> +</div> +{%endblock%} + +{%block sidebarcontents%} +{{display_population_card(species, population)}} +{%endblock%} diff --git a/uploader/templates/genotypes/index.html b/uploader/templates/genotypes/index.html new file mode 100644 index 0000000..b50ebc5 --- /dev/null +++ b/uploader/templates/genotypes/index.html @@ -0,0 +1,32 @@ +{%extends "genotypes/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "species/macro-select-species.html" import select_species_form%} + +{%block title%}Genotypes{%endblock%} + +{%block pagetitle%}Genotypes{%endblock%} + + +{%block contents%} +{{flash_all_messages()}} + +<div class="row"> + <p> + This section allows you to upload genotype information for your experiments, + in the case that you have not previously done so. + </p> + <p> + We'll need to link the genotypes to the species and population, so do please + go ahead and select those in the next two steps. + </p> +</div> + +<div class="row"> + {{select_species_form(url_for("species.populations.genotypes.index"), + species)}} +</div> +{%endblock%} + +{%block javascript%} +<script type="text/javascript" src="/static/js/species.js"></script> +{%endblock%} diff --git a/uploader/templates/genotypes/list-genotypes.html b/uploader/templates/genotypes/list-genotypes.html new file mode 100644 index 0000000..0f074fd --- /dev/null +++ b/uploader/templates/genotypes/list-genotypes.html @@ -0,0 +1,149 @@ +{%extends "genotypes/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "populations/macro-display-population-card.html" import display_population_card%} + +{%block title%}Genotypes{%endblock%} + +{%block pagetitle%}Genotypes{%endblock%} + +{%block lvl4_breadcrumbs%} +<li {%if activelink=="list-genotypes"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.genotypes.list_genotypes', + species_id=species.SpeciesId, + population_id=population.Id)}}">List genotypes</a> +</li> +{%endblock%} + +{%block contents%} +{{flash_all_messages()}} + +<div class="row"> + <h2>Genetic Markers</h2> + <p>There are a total of {{total_markers}} currently registered genetic markers + for the "{{species.FullName}}" species. You can click + <a href="{{url_for('species.populations.genotypes.list_markers', + species_id=species.SpeciesId, + population_id=population.Id)}}" + title="View genetic markers for species '{{species.FullName}}"> + this link to view the genetic markers + </a>. + </p> +</div> + +<div class="row"> + <h2>Genotype Encoding</h2> + <p> + The genotype encoding used for the "{{population.FullName}}" population from + the "{{species.FullName}}" species is as shown in the table below. + </p> + <table class="table"> + + <thead> + <tr> + <th>Allele Type</th> + <th>Allele Symbol</th> + <th>Allele Value</th> + </tr> + </thead> + + <tbody> + {%for row in genocode%} + <tr> + <td>{{row.AlleleType}}</td> + <td>{{row.AlleleSymbol}}</td> + <td>{{row.DatabaseValue if row.DatabaseValue is not none else "NULL"}}</td> + </tr> + {%else%} + <tr> + <td colspan="7" class="text-info"> + <span class="glyphicon glyphicon-exclamation-sign"></span> + There is no explicit genotype encoding defined for this population. + </td> + </tr> + {%endfor%} + </tbody> + </table> + + {%if genocode | length < 1%} + <a href="#add-genotype-encoding" + title="Add a genotype encoding system for this population" + class="btn btn-primary not-implemented"> + add genotype encoding + </a> + {%endif%} +</div> + +<div class="row text-danger"> + <h3>Some Important Concepts to Consider/Remember</h3> + <ul> + <li>Reference vs. Non-reference alleles</li> + <li>In <em>GenoCode</em> table, items are ordered by <strong>InbredSet</strong></li> + </ul> + <h3>Possible references</h3> + <ul> + <li>https://mr-dictionary.mrcieu.ac.uk/term/genotype/</li> + <li>https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363099/</li> + </ul> +</div> + +<div class="row"> + <h2>Genotype Datasets</h2> + + <p>The genotype data is organised under various genotype datasets. You can + click on the link for the relevant dataset to view a little more information + about it.</p> + + {%if dataset is not none%} + <table class="table"> + <thead> + <tr> + <th>Name</th> + <th>Full Name</th> + </tr> + </thead> + + <tbody> + <tr> + <td>{{dataset.Name}}</td> + <td><a href="{{url_for('species.populations.genotypes.view_dataset', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id)}}" + title="View details regarding and manage dataset '{{dataset.FullName}}'"> + {{dataset.FullName}}</a></td> + </tr> + </tbody> + </table> + {%else%} + <p class="text-warning"> + <span class="glyphicon glyphicon-exclamation-sign"></span> + There is no genotype dataset defined for this population. + </p> + <p> + <a href="{{url_for('species.populations.genotypes.create_dataset', + species_id=species.SpeciesId, + population_id=population.Id)}}" + title="Create a new genotype dataset for the '{{population.FullName}}' population for the '{{species.FullName}}' species." + class="btn btn-primary"> + create new genotype dataset</a></p> + {%endif%} +</div> +<div class="row text-warning"> + <p> + <span class="glyphicon glyphicon-exclamation-sign"></span> + <strong>NOTE</strong>: Currently the GN2 (and related) system(s) expect a + single genotype dataset. If there is more than one, the system apparently + fails in unpredictable ways. + </p> + <p>Fix this to allow multiple datasets, each with a different assembly from + all the rest.</p> +</div> +{%endblock%} + +{%block sidebarcontents%} +{{display_population_card(species, population)}} +{%endblock%} diff --git a/uploader/templates/genotypes/list-markers.html b/uploader/templates/genotypes/list-markers.html new file mode 100644 index 0000000..a705ae3 --- /dev/null +++ b/uploader/templates/genotypes/list-markers.html @@ -0,0 +1,105 @@ +{%extends "genotypes/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "species/macro-display-species-card.html" import display_species_card%} + +{%block title%}Genotypes: List Markers{%endblock%} + +{%block pagetitle%}Genotypes: List Markers{%endblock%} + +{%block lvl4_breadcrumbs%} +<li {%if activelink=="list-markers"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.genotypes.list_markers', + species_id=species.SpeciesId, + population_id=population.Id)}}">List markers</a> +</li> +{%endblock%} + +{%block contents%} +{{flash_all_messages()}} + +{%if markers | length > 0%} +<div class="row"> + <p> + There are a total of {{total_markers}} genotype markers for this species. + </p> + <div class="row"> + <div class="col-md-2" style="text-align: start;"> + {%if start_from > 0%} + <a href="{{url_for('species.populations.genotypes.list_markers', + species_id=species.SpeciesId, + population_id=population.Id, + start_from=start_from-count, + count=count)}}"> + <span class="glyphicon glyphicon-backward"></span> + Previous + </a> + {%endif%} + </div> + <div class="col-md-8" style="text-align: center;"> + Displaying markers {{start_from+1}} to {{start_from+count if start_from+count < total_markers else total_markers}} of + {{total_markers}} + </div> + <div class="col-md-2" style="text-align: end;"> + {%if start_from + count < total_markers%} + <a href="{{url_for('species.populations.genotypes.list_markers', + species_id=species.SpeciesId, + population_id=population.Id, + start_from=start_from+count, + count=count)}}"> + Next + <span class="glyphicon glyphicon-forward"></span> + </a> + {%endif%} + </div> + </div> + <table class="table"> + <thead> + <tr> + <th title="">#</th> + <th title="">Marker Name</th> + <th title="Chromosome">Chr</th> + <th title="Physical location of the marker in megabasepairs"> + Location (Mb)</th> + <th title="">Source</th> + <th title="">Source2</th> + </thead> + + <tbody> + {%for marker in markers%} + <tr> + <td>{{marker.sequence_number}}</td> + <td>{{marker.Marker_Name}}</td> + <td>{{marker.Chr}}</td> + <td>{{marker.Mb}}</td> + <td>{{marker.Source}}</td> + <td>{{marker.Source2}}</td> + </tr> + {%endfor%} + </tbody> + </table> +</div> +{%else%} +<div class="row"> + <p class="text-warning"> + <span class="glyphicon glyphicon-exclamation-sign"></span> + This species does not currently have any genetic markers uploaded, therefore, + there is nothing to display here. + </p> + <p> + <a href="#add-genetic-markers-for-species-{{species.SpeciesId}}" + title="Add genetic markers for this species" + class="btn btn-primary"> + add genetic markers + </a> + </p> +</div> +{%endif%} +{%endblock%} + +{%block sidebarcontents%} +{{display_species_card(species)}} +{%endblock%} diff --git a/uploader/templates/genotypes/select-population.html b/uploader/templates/genotypes/select-population.html new file mode 100644 index 0000000..acdd063 --- /dev/null +++ b/uploader/templates/genotypes/select-population.html @@ -0,0 +1,25 @@ +{%extends "genotypes/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "species/macro-display-species-card.html" import display_species_card%} +{%from "populations/macro-select-population.html" import select_population_form%} + +{%block title%}Genotypes{%endblock%} + +{%block pagetitle%}Genotypes{%endblock%} + + +{%block contents%} +{{flash_all_messages()}} + +<div class="row"> + {{select_population_form(url_for("species.populations.genotypes.select_population", species_id=species.SpeciesId), species, populations)}} +</div> +{%endblock%} + +{%block sidebarcontents%} +{{display_species_card(species)}} +{%endblock%} + +{%block javascript%} +<script type="text/javascript" src="/static/js/populations.js"></script> +{%endblock%} diff --git a/uploader/templates/genotypes/view-dataset.html b/uploader/templates/genotypes/view-dataset.html new file mode 100644 index 0000000..e7ceb36 --- /dev/null +++ b/uploader/templates/genotypes/view-dataset.html @@ -0,0 +1,61 @@ +{%extends "genotypes/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "populations/macro-display-population-card.html" import display_population_card%} + +{%block title%}Genotypes: View Dataset{%endblock%} + +{%block pagetitle%}Genotypes: View Dataset{%endblock%} + +{%block lvl4_breadcrumbs%} +<li {%if activelink=="view-dataset"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.genotypes.view_dataset', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id)}}">view dataset</a> +</li> +{%endblock%} + +{%block contents%} +{{flash_all_messages()}} + +<div class="row"> + <h2>Genotype Dataset Details</h2> + <table class="table"> + <thead> + <tr> + <th>Name</th> + <th>Full Name</th> + </tr> + </thead> + + <tbody> + <tr> + <td>{{dataset.Name}}</td> + <td>{{dataset.FullName}}</td> + </tr> + </tbody> + </table> +</div> + +<div class="row text-warning"> + <h2>Assembly Details</h2> + + <p>Maybe include the assembly details here if found to be necessary.</p> +</div> + +<div class="row"> + <h2>Genotype Data</h2> + + <p class="text-danger"> + Provide link to enable uploading of genotype data here.</p> +</div> + +{%endblock%} + +{%block sidebarcontents%} +{{display_population_card(species, population)}} +{%endblock%} diff --git a/uploader/templates/index.html b/uploader/templates/index.html index 94060b7..aa1414e 100644 --- a/uploader/templates/index.html +++ b/uploader/templates/index.html @@ -1,84 +1,107 @@ {%extends "base.html"%} {%from "flash_messages.html" import flash_all_messages%} -{%block title%}Data Upload{%endblock%} +{%block title%}Home{%endblock%} + +{%block pagetitle%}Home{%endblock%} {%block contents%} + <div class="row"> {{flash_all_messages()}} + <div class="explainer"> + <p>Welcome to the <strong>GeneNetwork Data Upload and Quality Control + System</strong>.</p> + <p>This tool helps you prepare and upload research data to GeneNetwork for + analysis.</p> - <h1 class="heading">data upload</h1> + <h2 class="heading">Getting Started</h2> + <p>The sections below explain the features of the system. Review this guide + to learn how to use the system.</p> - <div class="explainer"> - <p>Each of the sections below gives you a different option for data upload. - Please read the documentation for each section carefully to understand what - each section is about.</p> - </div> -</div> + {%block extrapageinfo%}{%endblock%} -<div class="row"> - <h2 class="heading">R/qtl2 Bundles</h2> + <h3 class="subheading">Species</h3> - <div class="explainer"> - <p>This feature combines and extends the two upload methods below. Instead of - uploading one item at a time, the R/qtl2 bundle you upload can contain both - the genotypes data (samples/individuals/cases and their data) and the - expression data.</p> - <p>The R/qtl2 bundle, additionally, can contain extra metadata, that neither - of the methods below can handle.</p> - - <a href="{{url_for('upload.rqtl2.select_species')}}" - title="Upload a zip bundle of R/qtl2 files"> - <button class="btn btn-primary">upload R/qtl2 bundle</button></a> - </div> -</div> + <p>GeneNetwork supports genetic studies across multiple species (e.g. mice + [Mus musculus], human [homo sapiens], rats [Rattus norvegicus], etc.) . + Here you can:</p> + <ul> + <li>View all species that are currently supported</li> + <li>Add new species not yet in the system</li> + </ul> + <h3 class="subheading">Populations</h3> -<div class="row"> - <h2 class="heading">Expression Data</h2> + <p>A "population" refers to a specific subgroup within a species that you’re + studying (e.g., BXD mice). Here you can:</p> + <ul> + <li>View the populations that exist for a selected species</li> + <li>Add new populations of study for a selected species</li> + </ul> - <div class="explainer"> - <p>This feature enables you to upload expression data. It expects the data to - be in <strong>tab-separated values (TSV)</strong> files. The data should be - a simple matrix of <em>phenotype × sample</em>, i.e. The first column is a - list of the <em>phenotypes</em> and the first row is a list of - <em>samples/cases</em>.</p> - - <p>If you haven't done so please go to this page to learn the requirements for - file formats and helpful suggestions to enter your data in a fast and easy - way.</p> - - <ol> - <li><strong>PLEASE REVIEW YOUR DATA.</strong>Make sure your data complies - with our system requirements. ( - <a href="{{url_for('entry.data_review')}}#data-concerns" - title="Details for the data expectations.">Help</a> - )</li> - <li><strong>UPLOAD YOUR DATA FOR DATA VERIFICATION.</strong> We accept - <strong>.csv</strong>, <strong>.txt</strong> and <strong>.zip</strong> - files (<a href="{{url_for('entry.data_review')}}#file-types" - title="Details for the data expectations.">Help</a>)</li> - </ol> - </div> + <h3 class="subheading">Samples</h3> - <a href="{{url_for('entry.upload_file')}}" - title="Upload your expression data" - class="btn btn-primary">upload expression data</a> -</div> + <p>Manage individual specimens or cases used in your experiments. These + include:</p> -<div class="row"> - <h2 class="heading">samples/cases</h2> + <ul> + <li>Experimental subjects</li> + <li>Data sources (e.g., tissue samples, clinical cases)</li> + <li>Strain means (instead of entering multiple BXD1 individuals, for + example, the mean would be entered for a single BXD1 strain)</li> + </ul> - <div class="explainer"> - <p>For the expression data above, you need the samples/cases in your file to - already exist in the GeneNetwork database. If there are any samples that do - not already exist the upload of the expression data will fail.</p> - <p>This section gives you the opportunity to upload any missing samples</p> - </div> - <a href="{{url_for('samples.select_species')}}" - title="Upload samples/cases/individuals for your data" - class="btn btn-primary">upload Samples/Cases</a> + <h3 class="subheading">Genotype Data</h3> + + <p>Upload and review genetic markers and allele encodings for your + population. Key details:</p> + + <ul> + <li>Markers are species-level (e.g., mouse SNP databases).</li> + <li>Allele data is population-specific (tied to your experimental + samples).</li> + </ul> + + <p><strong>Requirement</strong>: Samples must already have been registered + in the system before uploading genotype data.</p> + + <h3 class="subheading">Phenotype Data</h3> + + <p>Phenotypes are the visible traits or features of a living thing. For + example, phenotypes include:</p> + + <ul> + <li>Weight</li> + <li>Height</li> + <li>Color (such as the color of fur or eyes)</li> + </ul> + + <p>This part of the system will allow you to upload and manage the values + for different phenotypes from various samples in your studies.</p> + + <!-- + + <h3 class="subheading">Expression Data</h3> + + <p class="text-danger"> + <span class="glyphicon glyphicon-exclamation-sign"></span> + <strong>TODO</strong>: Document this …</p> + + <h3 class="subheading">Individual Data</h3> + + <p class="text-danger"> + <span class="glyphicon glyphicon-exclamation-sign"></span> + <strong>TODO</strong>: Document this …</p> + + <h3 class="subheading">RNA-Seq Data</h3> + + <p class="text-danger"> + <span class="glyphicon glyphicon-exclamation-sign"></span> + <strong>TODO</strong>: Document this …</p> + </div> + --> </div> {%endblock%} diff --git a/uploader/templates/jobs/job-error.html b/uploader/templates/jobs/job-error.html new file mode 100644 index 0000000..b3015fc --- /dev/null +++ b/uploader/templates/jobs/job-error.html @@ -0,0 +1,17 @@ +{%extends "base.html"%} + +{%from "flash_messages.html" import flash_all_messages%} + +{%block title%}Background Jobs: Error{%endblock%} + +{%block pagetitle%}Background Jobs: Error{%endblock%} + +{%block contents%} + +<h1>Background Jobs: Error</h1> +<p>Job <strong>{{job["job_id"]}}</strong> failed!</p> +<p>The error details are in the "STDERR" section below.</p> + +<h2>STDERR</h2> +<pre>{{job["stderr"]}}</pre> +{%endblock%} diff --git a/uploader/templates/jobs/job-not-found.html b/uploader/templates/jobs/job-not-found.html new file mode 100644 index 0000000..a71e66f --- /dev/null +++ b/uploader/templates/jobs/job-not-found.html @@ -0,0 +1,11 @@ +{%extends "base.html"%} + +{%from "flash_messages.html" import flash_all_messages%} + +{%block title%}Background Jobs{%endblock%} + +{%block pagetitle%}Background Jobs{%endblock%} + +{%block contents%} +<p>Could not find job with ID: {{job_id}}</p> +{%endblock%} diff --git a/uploader/templates/jobs/job-status.html b/uploader/templates/jobs/job-status.html new file mode 100644 index 0000000..83c02fd --- /dev/null +++ b/uploader/templates/jobs/job-status.html @@ -0,0 +1,24 @@ +{%extends "base.html"%} + +{%from "flash_messages.html" import flash_all_messages%} + +{%block extrameta%} +<meta http-equiv="refresh" content="5" /> +{%endblock%} + +{%block title%}Background Jobs{%endblock%} + +{%block pagetitle%}Background Jobs{%endblock%} + +{%block contents%} + +<p>Status: {{job["metadata"]["status"]}}</p> +<p>Job Type: {{job["metadata"]["job-type"]}}</p> + +<h2>STDOUT</h2> +<pre>{{job["stdout"]}}</pre> + +<h2>STDERR</h2> +<pre>{{job["stderr"]}}</pre> + +{%endblock%} diff --git a/uploader/templates/login.html b/uploader/templates/login.html index 6ebf72e..e76c644 100644 --- a/uploader/templates/login.html +++ b/uploader/templates/login.html @@ -1,32 +1,12 @@ -{%extends "base.html"%} -{%from "flash_messages.html" import flash_all_messages%} +{%extends "index.html"%} {%block title%}Data Upload{%endblock%} -{%block contents%} -<div class="row"> - {{flash_all_messages()}} - - <h1 class="heading">log in</h1> - - <div class="explainer"> - <p> - This system enables you to upload data onto GeneNetwork. In order to do - that correctly, we need to know who you are.</p> - <p> - If you already have an account with GeneNetwork, you can simply click the - login button below, after which you can upload your data.<br /> - </p> - <a href="{{authserver_authorise_uri()}}" class="btn btn-primary" - style="display:block;width:15em;align:center;margin:1em 3em;"> - log in</a> - <p> - If you do not have an account with GeneNetwork, go to - <a href="{{gn2server_uri()}}" - title="GeneNetwork Service." - target="_blank">GeneNetwork</a> - and register for an account, then come back here to login and upload.</a> - </div> -</div> +{%block pagetitle%}log in{%endblock%} +{%block extrapageinfo%} +<p class="text-dark"> + You <strong>need to + <a href="{{authserver_authorise_uri()}}" + title="Sign in to the system">sign in</a></strong> to use this system.</p> {%endblock%} diff --git a/uploader/templates/macro-step-indicator.html b/uploader/templates/macro-step-indicator.html new file mode 100644 index 0000000..ac0be77 --- /dev/null +++ b/uploader/templates/macro-step-indicator.html @@ -0,0 +1,15 @@ +{%macro step_indicator(step, width=100)%} +<svg width="{{width}}" height="{{width}}" xmlns="http://www.w3.org/2000/svg"> + <circle cx="{{0.5*width}}" + cy="{{0.5*width}}" + r="{{0.5*width}}" + fill="#E5E5FF" /> + <text x="{{0.5*width}}" + y="{{0.6*width}}" + font-size="{{0.2*width}}" + text-anchor="middle" + fill="#555555"> + Step {{step}} + </text> +</svg> +{%endmacro%} diff --git a/uploader/templates/macro-table-pagination.html b/uploader/templates/macro-table-pagination.html new file mode 100644 index 0000000..292c531 --- /dev/null +++ b/uploader/templates/macro-table-pagination.html @@ -0,0 +1,26 @@ +{%macro table_pagination(start_at, page_count, total_count, base_uri, name)%} +{%set ns = namespace(forward_uri=base_uri, back_uri=base_uri)%} +{%set ns.forward_uri="brr"%} + <div class="row"> + <div class="col-md-2" style="text-align: start;"> + {%if start_at > 0%} + <a href="{{base_uri + + '?start_at='+((start_at-page_count)|string) + + '&count='+(page_count|string)}}"> + <span class="glyphicon glyphicon-backward"></span> + Previous + </a> + {%endif%} + </div> + <div class="col-md-8" style="text-align: center;"> + Displaying {{name}} {{start_at+1}} to {{start_at+page_count if start_at+page_count < total_count else total_count}} of {{total_count}}</div> + <div class="col-md-2" style="text-align: end;"> + {%if start_at + page_count < total_count%} + <a href="{{base_uri + + '?start_at='+((start_at+page_count)|string) + + '&count='+(page_count|string)}}"> + Next<span class="glyphicon glyphicon-forward"></span></a> + {%endif%} + </div> + </div> +{%endmacro%} diff --git a/uploader/templates/parse_results.html b/uploader/templates/parse_results.html deleted file mode 100644 index e2bf7f0..0000000 --- a/uploader/templates/parse_results.html +++ /dev/null @@ -1,30 +0,0 @@ -{%extends "base.html"%} -{%from "errors_display.html" import errors_display%} - -{%block title%}Parse Results{%endblock%} - -{%block contents%} -<h1 class="heading">{{job_name}}: parse results</h2> - -{%if user_aborted%} -<span class="alert-warning">Job aborted by the user</span> -{%endif%} - -{{errors_display(errors, "No errors found in the file", "We found the following errors", True)}} - -{%if errors | length == 0 and not user_aborted %} -<form method="post" action="{{url_for('dbinsert.select_platform')}}"> - <input type="hidden" name="job_id" value="{{job_id}}" /> - <input type="submit" value="update database" class="btn btn-primary" /> -</form> -{%endif%} - -{%if errors | length > 0 or user_aborted %} -<br /> -<a href="{{url_for('entry.upload_file')}}" title="Back to index page." - class="btn btn-primary"> - Go back -</a> -{%endif%} - -{%endblock%} diff --git a/uploader/templates/phenotypes/add-phenotypes-base.html b/uploader/templates/phenotypes/add-phenotypes-base.html new file mode 100644 index 0000000..9909c20 --- /dev/null +++ b/uploader/templates/phenotypes/add-phenotypes-base.html @@ -0,0 +1,166 @@ +{%extends "phenotypes/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "macro-table-pagination.html" import table_pagination%} +{%from "phenotypes/macro-display-pheno-dataset-card.html" import display_pheno_dataset_card%} + +{%block title%}Phenotypes{%endblock%} + +{%block pagetitle%}Phenotypes{%endblock%} + +{%block lvl4_breadcrumbs%} +<li {%if activelink=="add-phenotypes"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.phenotypes.add_phenotypes', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id)}}">Add Phenotypes</a> +</li> +{%endblock%} + +{%block contents%} +{{flash_all_messages()}} + +<div class="row"> + <form id="frm-add-phenotypes" + method="POST" + enctype="multipart/form-data" + action="{{url_for('species.populations.phenotypes.add_phenotypes', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id, + use_bundle=use_bundle)}}" + data-resumable-target="{{url_for('files.resumable_upload_post')}}"> + <legend>Add New Phenotypes</legend> + + <div class="form-text help-block"> + {%block frm_add_phenotypes_documentation%}{%endblock%} + <p><strong class="text-warning">This will not update any existing phenotypes!</strong></p> + </div> + + {%block frm_add_phenotypes_elements%}{%endblock%} + + <fieldset id="fldset-publication-info"> + <legend>Publication Information</legend> + <input type="hidden" name="publication-id" id="txt-publication-id" /> + <span class="form-text text-muted"> + Select a publication for your data. <br /> + Can't find a publication you can use? Go ahead and + <a href="{{url_for( + 'publications.create_publication', + return_to='species.populations.phenotypes.add_phenotypes', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id)}}">create a new publication</a>.</span> + <table id="tbl-select-publication" class="table compact stripe"> + <thead> + <tr> + <th>#</th> + <th>PubMed ID</th> + <th>Title</th> + <th>Authors</th> + </tr> + </thead> + + <tbody></tbody> + </table> + </fieldset> + + <div class="form-group"> + <input type="submit" + value="upload phenotypes" + class="btn btn-primary" /> + </div> + </form> +</div> + +<div class="row"> + {%block page_documentation%}{%endblock%} +</div> + +{%endblock%} + + +{%block javascript%} +<script type="text/javascript"> + $(function() { + var publicationsDataTable = buildDataTable( + "#tbl-select-publication", + [], + [ + {data: "index"}, + { + searchable: true, + data: (pub) => { + if(pub.PubMed_ID) { + return `<a href="https://pubmed.ncbi.nlm.nih.gov/` + + `${pub.PubMed_ID}/" target="_blank" ` + + `title="Link to publication on NCBI.">` + + `${pub.PubMed_ID}</a>`; + } + return ""; + } + }, + { + searchable: true, + data: (pub) => { + var title = "⸻"; + if(pub.Title) { + title = pub.Title + } + return `<a href="/publications/view/${pub.Id}" ` + + `target="_blank" ` + + `title="Link to view publication details">` + + `${title}</a>`; + } + }, + { + searchable: true, + data: (pub) => { + authors = pub.Authors.split(",").map( + (item) => {return item.trim();}); + if(authors.length > 1) { + return authors[0] + ", et. al."; + } + return authors[0]; + } + } + ], + { + serverSide: true, + ajax: { + url: "/publications/list", + dataSrc: "publications" + }, + select: "single", + paging: true, + scrollY: 700, + deferRender: true, + scroller: true, + scrollCollapse: true, + layout: { + topStart: "info", + topEnd: "search" + } + }); + publicationsDataTable.on("select", (event, datatable, type, indexes) => { + indexes.forEach((element, index, thearray) => { + let row = datatable.row(element).node(); + console.debug(datatable.row(element).data()); + $("#frm-add-phenotypes #txt-publication-id").val( + datatable.row(element).data().Id); + }); + }); + publicationsDataTable.on("deselect", (event, datatable, type, indexes) => { + indexes.forEach((element, index, thearray) => { + let row = datatable.row(element).node(); + $("#frm-add-phenotypes #txt-publication-id").val(null); + }); + }); + }); +</script> + +{%block more_javascript%}{%endblock%} +{%endblock%} diff --git a/uploader/templates/phenotypes/add-phenotypes-raw-files.html b/uploader/templates/phenotypes/add-phenotypes-raw-files.html new file mode 100644 index 0000000..67b56e3 --- /dev/null +++ b/uploader/templates/phenotypes/add-phenotypes-raw-files.html @@ -0,0 +1,847 @@ +{%extends "phenotypes/add-phenotypes-base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "macro-table-pagination.html" import table_pagination%} +{%from "phenotypes/macro-display-pheno-dataset-card.html" import display_pheno_dataset_card%} +{%from "phenotypes/macro-display-preview-table.html" import display_preview_table%} +{%from "phenotypes/macro-display-resumable-elements.html" import display_resumable_elements%} + +{%block title%}Phenotypes{%endblock%} + +{%block pagetitle%}Phenotypes{%endblock%} + +{%block lvl4_breadcrumbs%} +<li {%if activelink=="add-phenotypes"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.phenotypes.add_phenotypes', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id)}}">Add Phenotypes</a> +</li> +{%endblock%} + +{%block frm_add_phenotypes_documentation%} +<p>This page will allow you to upload all the separate files that make up your + phenotypes. Here, you will have to upload each separate file individually. If + you want instead to upload all your files as a single ZIP file, + <a href="{{url_for('species.populations.phenotypes.add_phenotypes', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id, + use_bundle=true)}}" + title="">click here</a>.</p> +{%endblock%} + +{%block frm_add_phenotypes_elements%} +<fieldset id="fldset-file-metadata"> + <legend>File(s) Metadata</legend> + <div class="form-group"> + <label for="txt-file-separator" class="form-label">File Separator</label> + <div class="input-group"> + <input id="txt-file-separator" + name="file-separator" + type="text" + value="	" + class="form-control" + maxlength="1" /> + <span class="input-group-btn"> + <button id="btn-reset-file-separator" class="btn btn-info">Reset Default</button> + </span> + </div> + <span class="form-text text-muted"> + Provide the character that separates the fields in your file(s). It should + be the same character for all files (if more than one is provided).<br /> + A tab character will be assumed if you leave this field blank. See + <a href="#docs-file-separator" + title="Documentation for file-separator characters"> + documentation for more information</a>. + </span> + </div> + + <div class="form-group"> + <label for="txt-file-comment-character" class="form-label">File Comment-Character</label> + <div class="input-group"> + <input id="txt-file-comment-character" + name="file-comment-character" + type="text" + value="#" + class="form-control" + maxlength="1" /> + <span class="input-group-btn"> + <button id="btn-reset-file-comment-character" class="btn btn-info"> + Reset Default</button> + </span> + </div> + <span class="form-text text-muted"> + This specifies that lines that begin with the character provided will be + considered comment lines and ignored in their entirety. See + <a href="#docs-file-comment-character" + title="Documentation for comment characters"> + documentation for more information</a>. + </span> + </div> + + <div class="form-group"> + <label for="txt-file-na" class="form-label">File "No-Value" Indicators</label> + <div class="input-group"> + <input id="txt-file-na" + name="file-na" + type="text" + value="- NA N/A" + class="form-control" /> + <span class="input-group-btn"> + <button id="btn-reset-file-na" class="btn btn-info">Reset Default</button> + </span> + </div> + <span class="form-text text-muted"> + This specifies strings in your file indicate that there is no value for a + particular cell (a cell is where a column and row intersect). Provide a + space-separated list of strings if you have more than one way of + indicating no values. See + <a href="#docs-file-na" title="Documentation for no-value fields"> + documentation for more information</a>.</span> + </div> +</fieldset> + +<fieldset id="fldset-files"> + <legend>Data File(s)</legend> + + <fieldset id="fldset-descriptions-file"> + <div class="form-group"> + <div class="form-check"> + <input id="chk-phenotype-descriptions-transposed" + name="phenotype-descriptions-transposed" + type="checkbox" + class="form-check-input" + style="border: solid #8EABF0" /> + <label for="chk-phenotype-descriptions-transposed" + class="form-check-label"> + Description file transposed?</label> + </div> + + <div class="non-resumable-elements"> + <label for="finput-phenotype-descriptions" class="form-label"> + Phenotype Descriptions</label> + <input id="finput-phenotype-descriptions" + name="phenotype-descriptions" + class="form-control" + type="file" + data-preview-table="tbl-preview-pheno-desc" + required="required" /> + <span class="form-text text-muted"> + Provide a file that contains only the phenotype descriptions, + <a href="#docs-file-phenotype-description" + title="Documentation of the phenotype data file format."> + the documentation for the expected format of the file</a>.</span> + </div> + {{display_resumable_elements( + "resumable-phenotype-descriptions", + "phenotype descriptions", + '<p>Drag and drop the CSV file that contains the descriptions of your + phenotypes here.</p> + + <p>The CSV file should be a matrix of + <strong>phenotypes × descriptions</strong> i.e. The first column + contains the phenotype names/identifiers whereas the first row is a list + of metadata fields like, "description", "units", etc.</p> + + <p>If the format is transposed (i.e. + <strong>descriptions × phenotypes</strong>) select the checkbox above. + </p> + + <p>Please see the + <a href="#docs-file-phenotype-description" + title="Documentation of the phenotype data file format."> + "Phenotypes Descriptions" documentation</a> section below for more + information on the expected format of the file provided here.</p>')}} + {{display_preview_table( + "tbl-preview-pheno-desc", "phenotype descriptions")}} + </div> + </fieldset> + + + <fieldset id="fldset-data-file"> + <div class="form-group"> + <div class="form-check"> + <input id="chk-phenotype-data-transposed" + name="phenotype-data-transposed" + type="checkbox" + class="form-check-input" + style="border: solid #8EABF0" /> + <label for="chk-phenotype-data-transposed" class="form-check-label"> + Data file transposed?</label> + </div> + + <div class="non-resumable-elements"> + <label for="finput-phenotype-data" class="form-label">Phenotype Data</label> + <input id="finput-phenotype-data" + name="phenotype-data" + class="form-control" + type="file" + data-preview-table="tbl-preview-pheno-data" + required="required" /> + <span class="form-text text-muted"> + Provide a file that contains only the phenotype data. See + <a href="#docs-file-phenotype-data" + title="Documentation of the phenotype data file format."> + the documentation for the expected format of the file</a>.</span> + </div> + + {{display_resumable_elements( + "resumable-phenotype-data", + "phenotype data", + '<p>Drag and drop a CSV file that contains the phenotypes numerical data + here. You can click the "Browse" button (below and to the right) to + select the file from your computer.</p> + + <p>The CSV should be a matrix of <strong>samples × phenotypes</strong>, + i.e. The first column contains the samples identifiers while the first + row is the list of phenotypes identifiers occurring in the phenotypes + descriptions file.</p> + + <p>If the format is transposed (i.e <strong>phenotypes × samples</strong>) + select the checkbox above.</p> + <p>Please see the + <a href="#docs-file-phenotype-data" + title="Documentation of the phenotype data file format."> + "Phenotypes Data" documentation</a> section below for more information + on the expected format for the file provided here.</p>')}} + {{display_preview_table("tbl-preview-pheno-data", "phenotype data")}} + </div> + </fieldset> + + + {%if population.Family in families_with_se_and_n%} + <fieldset id="fldset-se-file"> + <div class="form-group"> + <div class="form-check"> + <input id="chk-phenotype-se-transposed" + name="phenotype-se-transposed" + type="checkbox" + class="form-check-input" + style="border: solid #8EABF0" /> + <label for="chk-phenotype-se-transposed" class="form-check-label"> + Standard-Errors file transposed?</label> + </div> + <div class="group non-resumable-elements"> + <label for="finput-phenotype-se" class="form-label">Phenotype: Standard Errors</label> + <input id="finput-phenotype-se" + name="phenotype-se" + class="form-control" + type="file" + data-preview-table="tbl-preview-pheno-se" + required="required" /> + <span class="form-text text-muted"> + Provide a file that contains only the standard errors for the phenotypes, + computed from the data above.</span> + </div> + + {{display_resumable_elements( + "resumable-phenotype-se", + "standard errors", + '<p>Drag and drop a CSV file that contains the phenotypes standard-errors + data here. You can click the "Browse" button (below and to the right) to + select the file from your computer.</p> + + <p>The CSV should be a matrix of <strong>samples × phenotypes</strong>, + i.e. The first column contains the samples identifiers while the first + row is the list of phenotypes identifiers occurring in the phenotypes + descriptions file.</p> + + <p>If the format is transposed (i.e <strong>phenotypes × samples</strong>) + select the checkbox above.</p> + + <p>Please see the + <a href="#docs-file-phenotype-se" + title="Documentation of the phenotype data file format."> + "Phenotypes Data" documentation</a> section below for more information + on the expected format of the file provided here.</p>')}} + + {{display_preview_table("tbl-preview-pheno-se", "standard errors")}} + </div> + </fieldset> + + + <fieldset id="fldset-n-file"> + <div class="form-group"> + <div class="form-check"> + <input id="chk-phenotype-n-transposed" + name="phenotype-n-transposed" + type="checkbox" + class="form-check-input" + style="border: solid #8EABF0" /> + <label for="chk-phenotype-n-transposed" class="form-check-label"> + Counts file transposed?</label> + </div> + <div class="non-resumable-elements"> + <label for="finput-phenotype-n" class="form-label">Phenotype: Number of Samples/Individuals</label> + <input id="finput-phenotype-n" + name="phenotype-n" + class="form-control" + type="file" + data-preview-table="tbl-preview-pheno-n" + required="required" /> + <span class="form-text text-muted"> + Provide a file that contains only the number of samples/individuals used in + the computation of the standard errors above.</span> + </div> + + {{display_resumable_elements( + "resumable-phenotype-n", + "number of samples/individuals", + '<p>Drag and drop a CSV file that contains the samples\' phenotypes counts + data here. You can click the "Browse" button (below and to the right) to + select the file from your computer.</p> + + <p>The CSV should be a matrix of <strong>samples × phenotypes</strong>, + i.e. The first column contains the samples identifiers while the first + row is the list of phenotypes identifiers occurring in the phenotypes + descriptions file.</p> + + <p>If the format is transposed (i.e <strong>phenotypes × samples</strong>) + select the checkbox above.</p> + + <p>Please see the + <a href="#docs-file-phenotype-se" + title="Documentation of the phenotype data file format."> + "Phenotypes Data" documentation</a> section below for more information + on the expected format of the file provided here.</p>')}} + + {{display_preview_table("tbl-preview-pheno-n", "number of samples/individuals")}} + </div> + </fieldset> +</fieldset> +{%endif%} +{%endblock%} + + +{%block page_documentation%} +<div class="row"> + <h2 class="heading" id="docs-help">Help</h2> + <h3 class="subheading">Common Features</h3> + <p>The following are the common expectations for <strong>ALL</strong> the + files provided in the form above: + <ul> + <li>The file <strong>MUST</strong> be character-separated values (CSV) + text file</li> + <li>The first row in the file <strong>MUST</strong> be a heading row, and + will be composed of the list identifiers for all of + samples/individuals/cases involved in your study.</li> + <li>The first column of data in the file <strong>MUST</strong> be the + identifiers for all of the phenotypes you wish to upload.</li> + </ul> + </p> + + <p>If you do not specify the separator character, then we will assume a + <strong>TAB</strong> character was used as your separator.</p> + + <p>We also assume you might include comments lines in your files. In that + case, if you do not specify what character denotes that a line in your files + is a comment line, we will assume the <strong>#</strong> character.<br /> + A comment <strong>MUST ALWAYS</strong> begin at the start of the line marked + with the comment character specified.</p> + + <h3 class="subheading" id="docs-file-metadata">File Metadata</h3> + <p>We request some details about your files to help us parse and process the + files correctly. The details we collect are:</p> + <dl> + <dt id="docs-file-separator">File separator</dt> + <dd>The files you provide should be character-separated value (CSV) files. + We need to know what character you used to separate the values in your + file. Some common ones are the Tab character, the comma, etc.<br /> + Providing that information makes it possible for the system to parse and + process your files correctly.<br> + <strong>NOTE:</strong> All the files you upload MUST use the same + separator.</dd> + + <dt id="docs-file-comment-character">Comment character</dt> + <dd>We support use of comment lines in your files. We only support one type + of comment style, the <em>line comment</em>.<br /> + This mean the comment begins at the start of the line, and the end of that + line indicates the end of that comment. If you have a really long comment, + then you need to break it across multiple lines, marking each line a + comment line.<br /> + The "comment character" is the character at the start of the line that + indicates that the line is a line comment.</dd> + + <dt id="docs-file-na">No-Value indicator(s)</dt> + <dd>Data in the real world is messy, and in some cases, entirely absent. You + need to indicate, in your files, that a particular field did not have a + value, and once you do that, you then need to let the system know how you + mark such fields. Common ways of indicating "empty values" are, leaving + the field blank, using a character such as '-', or using strings like + "NA", "N/A", "NULL", etc.<br /> + Providing this information will help with parsing and processing such + no-value fields the correct way.</dd> + </dl> + + <h3 class="subheading" id="docs-file-phenotype-description"> + file: Phenotypes Descriptions</h3> + <p>The data in this file is a matrix of <em>phenotypes × metadata-fields</em>. + Please note we use the term "metadata-fields" above loosely, due to lack of + a good word for this.</p> + <p>The file <strong>MUST</strong> have columns in this order: + <dl> + <dt>Phenotype Identifiers</dt> + <dd>These are the names/identifiers for your phenotypes. These + names/identifiers are the same ones you will have in all the other files you are + uploading.</dd> + + <dt>Descriptions</dt> + <dd>Each phenotype will need a description. Good description are necessary + to inform other people of what the data is about. Good description are + hard to construct, so we provide + <a href="https://info.genenetwork.org/faq.php#q-22" + title="How to write phenotype descriptions"> + advice on describing your phenotypes.</a></dd> + + <dt>Units</dt> + <dd>Each phenotype will need units for the measurements taken. If there are + none, then indicate the field is a no-value field.</dd> + </dl></p> + <p>You can add more columns after those three if you want to, but these 3 + <strong>MUST</strong> be present.</p> + <p>The file would, for example, look like the following:</p> + <code>id,description,units,…<br /> + pheno10001|Central nervous system, behavior, cognition; …|mg|…<br /> + pheno10002|Aging, metabolism, central nervous system: …|mg|…<br /> + â‹®<br /></code> + + <p><strong>Note 01</strong>: The first usable row is the heading row.</p> + <p><strong>Note 02: </strong>This example demonstrates a subtle issue that + could make your CSV file invalid — the choice of your field separator + character.<br > + In the example above, we use the pipe character (<code>|</code>) as our + field separator. This is because, if we follow the advice on how to write + good descriptions, then we cannot use the comma as our separator – if + we did, then our CSV file would be invalid because the system would have no + way to tell the difference between the comma as a field separator, and the + comma as a way to separate the "general category and ontology terms".</p> + + <h3 class="subheading">file: Phenotype Data, Standard Errors and/or Sample Counts</h3> + <span id="docs-file-phenotype-data"></span> + <span id="docs-file-phenotype-se"></span> + <span id="docs-file-phenotype-n"></span> + <p>The data is a matrix of <em>samples(or individuals) × phenotypes</em>, e.g.</p> + <code> + # num-cases: 2549 + # num-phenos: 13 + id,pheno10001,pheno10002,pheno10003,pheno10004,53.099998,…<br /> + IND001,61.400002,49,62.5,55.099998,…<br /> + IND002,54.099998,50.099998,53.299999,55.099998,…<br /> + IND003,483,403,501,403,…<br /> + IND004,49.799999,45.5,62.900002,NA,…<br /> + â‹®<br /></code> + + <p>where <code>IND001,IND002,IND003,IND004,…</code> are the + samples/individuals/cases in your study, and + <code>pheno10001,pheno10002,pheno10004,pheno10004,…</code> are the + identifiers for your phenotypes.</p> + <p>The lines beginning with the "<em>#</em>" symbol (i.e. + <code># num-cases: 2549</code> and <code># num-phenos: 13</code> are comment + lines and will be ignored</p> + <p>In this example, the comma (,) is used as the file separator.</p> +</div> + +{%endblock%} + +{%block sidebarcontents%} +{{display_pheno_dataset_card(species, population, dataset)}} +{%endblock%} + + +{%block more_javascript%} +<script src="{{url_for('base.node_modules', + filename='resumablejs/resumable.js')}}"></script> +<script type="text/javascript" src="/static/js/files.js"></script> + +<script type="text/javascript"> + $("#btn-reset-file-separator").on("click", (event) => { + event.preventDefault(); + $("#txt-file-separator").val("\t"); + $("#txt-file-separator").trigger("change"); + }); + $("#btn-reset-file-comment-character").on("click", (event) => { + event.preventDefault(); + $("#txt-file-comment-character").val("#"); + $("#txt-file-comment-character").trigger("change"); + }); + $("#btn-reset-file-na").on("click", (event) => { + event.preventDefault(); + $("#txt-file-na").val("- NA N/A"); + $("#txt-file-na").trigger("change"); + }); + + var update_preview = (table, filedata, formdata, numrows) => { + table.find("thead tr").remove() + table.find(".data-row").remove(); + var linenum = 0; + var tableheader = table.find("thead"); + var tablebody = table.find("tbody"); + var numheadings = 0; + var navalues = formdata + .na_strings + .split(" ") + .map((v) => {return v.trim();}) + .filter((v) => {return Boolean(v);}); + filedata.forEach((line) => { + if(line.startsWith(formdata.comment_char) || linenum >= numrows) { + return false; + } + var row = $("<tr></tr>"); + line.split(formdata.separator) + .map((field) => { + var value = field.trim(); + if(navalues.includes(value)) { + return "⋘NULâ‹™"; + } + return value; + }) + .filter((field) => { + return (field !== "" && field != undefined && field != null); + }) + .forEach((field) => { + if(linenum == 0) { + numheadings += 1; + var tablefield = $("<th></th>"); + tablefield.text(field); + row.append(tablefield); + } else { + add_class(row, "data-row"); + var tablefield = $("<td></td>"); + tablefield.text(field); + row.append(tablefield); + } + }); + + if(linenum == 0) { + tableheader.append(row); + } else { + tablebody.append(row); + } + linenum += 1; + }); + + if(table.find("tbody tr.data-row").length > 0) { + add_class(table.find(".data-row-template"), "visually-hidden"); + } else { + remove_class(table.find(".data-row-template"), "visually-hidden"); + } + }; + + var makePreviewUpdater = (preview_table) => { + return (data) => { + update_preview( + preview_table, + data, + filesMetadata(), + PREVIEW_ROWS); + }; + }; + + var preview_tables_to_elements_map = { + "#tbl-preview-pheno-desc": "#finput-phenotype-descriptions", + "#tbl-preview-pheno-data": "#finput-phenotype-data", + "#tbl-preview-pheno-se": "#finput-phenotype-se", + "#tbl-preview-pheno-n": "#finput-phenotype-n" + }; + + var filesMetadata = () => { + return { + "separator": $("#txt-file-separator").val(), + "comment_char": $( + "#txt-file-comment-character").val(), + "na_strings": $("#txt-file-na").val() + } + }; + + var PREVIEW_ROWS = 5; + + var handler_update_previews = (event) => { + Object.entries(preview_tables_to_elements_map).forEach((mapentry) => { + var preview_table = $(mapentry[0]); + var file_input = $(mapentry[1]); + if(file_input[0].files.length > 0) { + readFirstNLines( + file_input[0].files[0], + 10, + [makePreviewUpdater(preview_table)]); + } + }); + + if(typeof(resumables) !== "undefined") { + resumables.forEach((resumable) => { + if(resumable.files.length > 0) { + readFirstNLines( + resumable.files[0].file, + 10, + [makePreviewUpdater(resumable.preview_table)]); + } + }); + } + }; + + [ + "#txt-file-separator", + "#txt-file-comment-character", + "#txt-file-na" + ].forEach((elementid) => { + $(elementid).on("change", handler_update_previews); + }); + + [ + "#finput-phenotype-descriptions", + "#finput-phenotype-data", + "#finput-phenotype-se", + "#finput-phenotype-n" + ].forEach((elementid) => { + $(elementid).on("change", (event) => { + readFirstNLines( + event.target.files[0], + 10, + [makePreviewUpdater( + $("#" + event.target.getAttribute("data-preview-table")))]); + }); + }); + + + var resumableDisplayFiles = (display_area, files) => { + files.forEach((file) => { + display_area.find(".file-display").remove(); + var display_element = display_area + .find(".file-display-template") + .clone(); + remove_class(display_element, "visually-hidden"); + remove_class(display_element, "file-display-template"); + add_class(display_element, "file-display"); + display_element.find(".filename").text(file.name + || file.fileName + || file.relativePath + || file.webkitRelativePath); + display_element.find(".filesize").text( + (file.size / (1024*1024)).toFixed(2) + "MB"); + display_element.find(".fileuniqueid").text(file.uniqueIdentifier); + display_element.find(".filemimetype").text(file.file.type); + display_area.append(display_element); + }); + }; + + + var indicateProgress = (resumable, progress_bar) => { + return () => {/*Has no event!*/ + var progress = (resumable.progress() * 100).toFixed(2); + var pbar = progress_bar.find(".progress-bar"); + remove_class(progress_bar, "visually-hidden"); + pbar.css("width", progress+"%"); + pbar.attr("aria-valuenow", progress); + pbar.text("Uploading: " + progress + "%"); + }; + }; + + var retryUpload = (retry_button, cancel_button) => { + retry_button.on("click", (event) => { + resumable.files.forEach((file) => {file.retry();}); + add_class(retry_button, "visually-hidden"); + remove_class(cancel_button, "visually-hidden"); + add_class(browse_button, "visually-hidden"); + }); + }; + + var cancelUpload = (cancel_button, retry_button) => { + cancel_button.on("click", (event) => { + resumable.files.forEach((file) => { + if(file.isUploading()) { + file.abort(); + } + }); + add_class(cancel_button, "visually-hidden"); + remove_class(retry_button, "visually-hidden"); + remove_class(browse_button, "visually-hidden"); + }); + }; + + + var startUpload = (browse_button, retry_button, cancel_button) => { + return (event) => { + remove_class(cancel_button, "visually-hidden"); + add_class(retry_button, "visually-hidden"); + add_class(browse_button, "visually-hidden"); + }; + }; + + var processForm = (form) => { + var formdata = new FormData(form); + uploaded_files.forEach((msg) => { + formdata.delete(msg["file-input-name"]); + formdata.append(msg["file-input-name"], JSON.stringify({ + "uploaded-file": msg["uploaded-file"], + "original-name": msg["original-name"] + })); + }); + formdata.append("resumable-upload", "true"); + formdata.append("publication-id", $("#txt-publication-id").val()); + return formdata; + } + + var uploaded_files = new Set(); + var submitForm = (new_file) => { + uploaded_files.add(new_file); + if(uploaded_files.size === resumables.length) { + var form = $("#frm-add-phenotypes"); + if(form.length !== 1) { + // TODO: Handle error somehow? + alert("Could not find form!!!"); + return false; + } + + $.ajax({ + "url": form.attr("action"), + "type": "POST", + "data": processForm(form[0]), + "processData": false, + "contentType": false, + "success": (data, textstatus, jqxhr) => { + // TODO: Redirect to endpoint that should come as part of the + // success/error message. + console.log("SUCCESS DATA: ", data); + console.log("SUCCESS STATUS: ", textstatus); + console.log("SUCCESS jqXHR: ", jqxhr); + window.location.assign(window.location.origin + data["redirect-to"]); + }, + }); + return false; + } + return false; + }; + + var uploadSuccess = (file_input_name) => { + return (file, message) => { + submitForm({...JSON.parse(message), "file-input-name": file_input_name}); + }; + }; + + + var uploadError = () => { + return (message, file) => { + $("#frm-add-phenotypes input[type=submit]").removeAttr("disabled"); + console.log("THE FILE:", file); + console.log("THE ERROR MESSAGE:", message); + }; + }; + + + + var makeResumableObject = (form_id, file_input_id, resumable_element_id, preview_table_id) => { + var the_form = $("#" + form_id); + var file_input = $("#" + file_input_id); + var submit_button = the_form.find("input[type=submit]"); + if(file_input.length != 1) { + return false; + } + var r = errorHandler( + fileSuccessHandler( + uploadStartHandler( + filesAddedHandler( + markResumableDragAndDropElement( + makeResumableElement( + the_form.attr("data-resumable-target"), + file_input.parent(), + $("#" + resumable_element_id), + submit_button, + ["csv", "tsv", "txt"]), + file_input.parent(), + $("#" + resumable_element_id), + $("#" + resumable_element_id + "-browse-button")), + (files) => { + // TODO: Also trigger preview! + resumableDisplayFiles( + $("#" + resumable_element_id + "-selected-files"), files); + files.forEach((file) => { + readFirstNLines( + file.file, + 10, + [makePreviewUpdater( + $("#" + preview_table_id))]) + }); + }), + startUpload($("#" + resumable_element_id + "-browse-button"), + $("#" + resumable_element_id + "-retry-button"), + $("#" + resumable_element_id + "-cancel-button"))), + uploadSuccess(file_input.attr("name"))), + uploadError()); + + /** Setup progress indicator **/ + progressHandler( + r, + indicateProgress(r, $("#" + resumable_element_id + "-progress-bar"))); + + return r; + }; + + var resumables = [ + ["frm-add-phenotypes", "finput-phenotype-descriptions", "resumable-phenotype-descriptions", "tbl-preview-pheno-desc"], + ["frm-add-phenotypes", "finput-phenotype-data", "resumable-phenotype-data", "tbl-preview-pheno-data"], + ["frm-add-phenotypes", "finput-phenotype-se", "resumable-phenotype-se", "tbl-preview-pheno-se"], + ["frm-add-phenotypes", "finput-phenotype-n", "resumable-phenotype-n", "tbl-preview-pheno-n"], + ].map((row) => { + r = makeResumableObject(row[0], row[1], row[2], row[3]); + r.preview_table = $("#" + row[3]); + return r; + }).filter((val) => { + return Boolean(val); + }); + + $("#frm-add-phenotypes input[type=submit]").on("click", (event) => { + event.preventDefault(); + console.debug(); + if ($("#txt-publication-id").val() == "") { + alert("You MUST provide a publication for the phenotypes."); + return false; + } + // TODO: Check all the relevant files exist + // TODO: Verify that files are not duplicated + var filenames = []; + var nondupfiles = []; + resumables.forEach((r) => { + var fname = r.files[0].file.name; + filenames.push(fname); + if(!nondupfiles.includes(fname)) { + nondupfiles.push(fname); + } + }); + + // Check that all files were provided + if(resumables.length !== filenames.length) { + window.alert("You MUST provide all the files requested."); + event.target.removeAttribute("disabled"); + return false; + } + + // Check that there are no duplicate files + var duplicates = Object.entries(filenames.reduce( + (acc, curr, idx, arr) => { + acc[curr] = (acc[curr] || 0) + 1; + return acc; + }, + {})).filter((entry) => {return entry[1] !== 1;}); + if(duplicates.length > 0) { + var msg = "The file(s):\r\n"; + msg = msg + duplicates.reduce( + (msgstr, afile) => { + return msgstr + " • " + afile[0] + "\r\n"; + }, + ""); + msg = msg + "is(are) duplicated. Please fix and try again."; + window.alert(msg); + event.target.removeAttribute("disabled"); + return false; + } + // TODO: Check all fields + // Start the uploads. + event.target.setAttribute("disabled", "disabled"); + resumables.forEach((r) => {r.upload();}); + }); +</script> +{%endblock%} diff --git a/uploader/templates/phenotypes/add-phenotypes-with-rqtl2-bundle.html b/uploader/templates/phenotypes/add-phenotypes-with-rqtl2-bundle.html new file mode 100644 index 0000000..898fc0c --- /dev/null +++ b/uploader/templates/phenotypes/add-phenotypes-with-rqtl2-bundle.html @@ -0,0 +1,207 @@ +{%extends "phenotypes/add-phenotypes-base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "macro-table-pagination.html" import table_pagination%} +{%from "phenotypes/macro-display-pheno-dataset-card.html" import display_pheno_dataset_card%} + +{%block title%}Phenotypes{%endblock%} + +{%block pagetitle%}Phenotypes{%endblock%} + +{%block lvl4_breadcrumbs%} +<li {%if activelink=="add-phenotypes"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.phenotypes.add_phenotypes', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id)}}">Add Phenotypes</a> +</li> +{%endblock%} + +{%block frm_add_phenotypes_documentation%} +<p>Select the zip file bundle containing information on the phenotypes you + wish to upload, then click the "Upload Phenotypes" button below to + upload the data.</p> +<p>If you wish to upload the files individually instead, + <a href="{{url_for('species.populations.phenotypes.add_phenotypes', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id)}}" + title="">click here</a>.</p> +<p>See the <a href="#section-file-formats">File Formats</a> section below + to get an understanding of what is expected of the bundle files you + upload.</p> +{%endblock%} + +{%block frm_add_phenotypes_elements%} +<div class="form-group"> + <label for="finput-phenotypes-bundle" class="form-label"> + Phenotypes Bundle</label> + <input type="file" + id="finput-phenotypes-bundle" + name="phenotypes-bundle" + accept="application/zip, .zip" + required="required" + class="form-control" /> +</div> +{%endblock%} + +{%block page_documentation%} +<div class="row"> + <h2 class="heading" id="section-file-formats">File Formats</h2> + <p>We accept an extended form of the + <a href="https://kbroman.org/qtl2/assets/vignettes/input_files.html#format-of-the-data-files" + title="R/qtl2 software input file format documentation"> + input files' format used with the R/qtl2 software</a> as a single ZIP + file</p> + <p>The files that are used for this feature are: + <ul> + <li>the <em>control</em> file</li> + <li><em>pheno</em> file(s)</li> + <li><em>phenocovar</em> file(s)</li> + <li><em>phenose</em> files(s)</li> + </ul> + </p> + <p>Other files within the bundle will be ignored, for this feature.</p> + <p>The following section will detail the expectations for each of the + different file types within the uploaded ZIP file bundle for phenotypes:</p> + + <h3 class="subheading">Control File</h3> + <p>There <strong>MUST be <em>one, and only one</em></strong> file that acts + as the control file. This file can be: + <ul> + <li>a <em>JSON</em> file, or</li> + <li>a <em>YAML</em> file.</li> + </ul> + </p> + + <p>The control file is useful for defining things about the bundle such as:</p> + <ul> + <li>The field separator value (default: <code>sep: ','</code>). There can + only ever be one field separator and it <strong>MUST</strong> be the same + one for <strong>ALL</strong> files in the bundle.</li> + <li>The comment character (default: <code>comment.char: '#'</code>). Any + line that starts with this character will be considered a comment line and + be ignored in its entirety.</li> + <li>Code for missing values (default: <code>na.strings: 'NA'</code>). You + can specify more than one code to indicate missing values, e.g. + <code>{…, "na.strings": ["NA", "N/A", "-"], …}</code></li> + </ul> + + <h3 class="subheading"><em>pheno</em> File(s)</h3> + <p>These files are the main data files. You must have at least one of these + files in your bundle for it to be valid for this step.</p> + <p>The data is a matrix of <em>individuals × phenotypes</em> by default, as + below:<br /> + <code> + id,10001,10002,10003,10004,…<br /> + BXD1,61.400002,54.099998,483,49.799999,…<br /> + BXD2,49,50.099998,403,45.5,…<br /> + BXD5,62.5,53.299999,501,62.900002,…<br /> + BXD6,53.099998,55.099998,403,NA,…<br /> + â‹®<br /></code> + </p> + <p>If the <code>pheno_transposed</code> value is set to <code>True</code>, + then the data will be a <em>phenotypes × individuals</em> matrix as in the + example below:<br /> + <code> + id,BXD1,BXD2,BXD5,BXD6,…<br /> + 10001,61.400002,49,62.5,53.099998,…<br /> + 10002,54.099998,50.099998,53.299999,55.099998,…<br /> + 10003,483,403,501,403,…<br /> + 10004,49.799999,45.5,62.900002,NA,…<br /> + â‹® + </code> + </p> + + + <h3 class="subheading"><em>phenocovar</em> File(s)</h3> + <p>At least one phenotypes metadata file with the metadata values such as + descriptions, PubMed Identifier, publication titles (if present), etc.</p> + <p>The data in this/these file(s) is a matrix of + <em>phenotypes × phenotypes-covariates</em>. The first column is always the + phenotype names/identifiers — same as in the R/qtl2 format.</p> + <p><em>phenocovar</em> files <strong>should never be transposed</strong>!</p> + <p>This file <strong>MUST</strong> be present in the bundle, and have data for + the bundle to be considered valid by our system for this step.<br /> + In addition to that, the following are the fields that <strong>must be + present</strong>, and + have values, in the file before the file is considered valid: + <ul> + <li><em>description</em>: A description for each phenotype. Useful + for users to know what the phenotype is about.</li> + <li><em>units</em>: The units of measurement for the phenotype, + e.g. milligrams for brain weight, centimetres/millimetres for + tail-length, etc.</li> + </ul></p> + + <p>The following <em>optional</em> fields can also be provided: + <ul> + <li><em>pubmedid</em>: A PubMed Identifier for the publication where + the phenotype is published. If this field is not provided, the system will + assume your phenotype is not published.</li> + </ul> + </p> + <p>These files will be marked up in the control file with the + <code>phenocovar</code> key, as in the examples below: + <ol> + <li>JSON: single file<br /> + <code>{<br /> + â‹®,<br /> + "phenocovar": "your_covariates_file.csv",<br /> + â‹®<br /> + } + </code> + </li> + <li>JSON: multiple files<br /> + <code>{<br /> + â‹®,<br /> + "phenocovar": [<br /> + "covariates_file_01.csv",<br /> + "covariates_file_01.csv",<br /> + â‹®<br /> + ],<br /> + â‹®<br /> + } + </code> + </li> + <li>YAML: single file or<br /> + <code> + â‹®<br /> + phenocovar: your_covariates_file.csv<br /> + â‹® + </code> + </li> + <li>YAML: multiple files<br /> + <code> + â‹®<br /> + phenocovar:<br /> + - covariates_file_01.csv<br /> + - covariates_file_02.csv<br /> + - covariates_file_03.csv<br /> + …<br /> + â‹® + </code> + </li> + </ol> + </p> + + <h3 class="subheading"><em>phenose</em> and <em>phenonum</em> File(s)</h3> + <p>These are extensions to the R/qtl2 standard, i.e. these types ofs file are + not supported by the original R/qtl2 file format</p> + <p>We use these files to upload the standard errors (<em>phenose</em>) when + the data file (<em>pheno</em>) is average data. In that case, the + <em>phenonum</em> file(s) contains the number of individuals that were + involved when computing the averages.</p> + <p>Both types of files are matrices of <em>individuals × phenotypes</em> by + default. Like the related <em>pheno</em> files, if + <code>pheno_transposed: True</code>, then the file will be a matrix of + <em>phenotypes × individuals</em>.</p> +</div> +{%endblock%} + +{%block sidebarcontents%} +{{display_pheno_dataset_card(species, population, dataset)}} +{%endblock%} diff --git a/uploader/templates/phenotypes/base.html b/uploader/templates/phenotypes/base.html new file mode 100644 index 0000000..adbc012 --- /dev/null +++ b/uploader/templates/phenotypes/base.html @@ -0,0 +1,19 @@ +{%extends "populations/base.html"%} + +{%block lvl3_breadcrumbs%} +<li {%if activelink=="phenotypes"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + {%if dataset is mapping%} + <a href="{{url_for('species.populations.phenotypes.view_dataset', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id)}}">{{dataset.Name}}</a> + {%else%} + <a href="{{url_for('species.populations.phenotypes.index')}}">Phenotypes</a> + {%endif%} +</li> +{%block lvl4_breadcrumbs%}{%endblock%} +{%endblock%} diff --git a/uploader/templates/phenotypes/bulk-edit-upload.html b/uploader/templates/phenotypes/bulk-edit-upload.html new file mode 100644 index 0000000..d0f38f5 --- /dev/null +++ b/uploader/templates/phenotypes/bulk-edit-upload.html @@ -0,0 +1,62 @@ +{%extends "phenotypes/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "macro-table-pagination.html" import table_pagination%} +{%from "populations/macro-display-population-card.html" import display_population_card%} + +{%block title%}Phenotypes{%endblock%} + +{%block pagetitle%}Phenotypes{%endblock%} + +{%block lvl4_breadcrumbs%} +<li {%if activelink=="view-dataset"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.phenotypes.view_dataset', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id)}}">View</a> +</li> +{%endblock%} + +{%block contents%} +<div class="row"> + <p>Upload the edited file you downloaded and edited.</p> +</div> + +<div class="row"> + <form id="frm-bulk-edit-upload" + class="form-horizontal" + method="POST" + action="{{url_for( + 'species.populations.phenotypes.edit_upload_phenotype_data', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id)}}" + enctype="multipart/form-data"> + + <div class="form-group row"> + <label for="file-upload-bulk-edit-upload" + class="form-label col-form-label col-sm-2"> + Edited File</label> + <div class="col-sm-10"> + <input id="file-upload-bulk-edit-upload" + name="file-upload-bulk-edit-upload" + class="form-control" + type="file" + accept="text/tab-separated-values" + required="required" /> + </div> + </div> + + <input type="submit" class="btn btn-primary" + value="upload to edit" /> + + </form> +</div> +{%endblock%} + + +{%block javascript%} +{%endblock%} diff --git a/uploader/templates/phenotypes/create-dataset.html b/uploader/templates/phenotypes/create-dataset.html new file mode 100644 index 0000000..19a2b34 --- /dev/null +++ b/uploader/templates/phenotypes/create-dataset.html @@ -0,0 +1,108 @@ +{%extends "phenotypes/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "macro-table-pagination.html" import table_pagination%} +{%from "populations/macro-display-population-card.html" import display_population_card%} + +{%block title%}Phenotypes{%endblock%} + +{%block pagetitle%}Phenotypes{%endblock%} + +{%block lvl4_breadcrumbs%} +<li {%if activelink=="create-dataset"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.phenotypes.create_dataset', + species_id=species.SpeciesId, + population_id=population.Id)}}">Create Datasets</a> +</li> +{%endblock%} + +{%block contents%} +{{flash_all_messages()}} + +<div class="row"> + <p>Create a new phenotype dataset.</p> +</div> + +<div class="row"> + <form id="frm-create-pheno-dataset" + action="{{url_for('species.populations.phenotypes.create_dataset', + species_id=species.SpeciesId, + population_id=population.Id)}}" + method="POST"> + + <div class="form-group"> + <label class="form-label" for="txt-dataset-name">Name</label> + {%if errors["dataset-name"] is defined%} + <small class="form-text text-muted danger"> + <p>{{errors["dataset-name"]}}</p></small> + {%endif%} + <input type="text" + name="dataset-name" + id="txt-dataset-name" + value="{{original_formdata.get('dataset-name') or (population.Name + 'Publish')}}" + {%if errors["dataset-name"] is defined%} + class="form-control danger" + {%else%} + class="form-control" + {%endif%} + required="required" /> + <small class="form-text text-muted"> + <p>A short representative name for the dataset.</p> + <p>Recommended: Use the population name and append "Publish" at the end. + <br />This field will only accept names composed of + letters ('A-Za-z'), numbers (0-9), hyphens and underscores.</p> + </small> + </div> + + <div class="form-group"> + <label class="form-label" for="txt-dataset-fullname">Full Name</label> + {%if errors["dataset-fullname"] is defined%} + <small class="form-text text-muted danger"> + <p>{{errors["dataset-fullname"]}}</p></small> + {%endif%} + <input id="txt-dataset-fullname" + name="dataset-fullname" + type="text" + value="{{original_formdata.get('dataset-fullname', '')}}" + {%if errors["dataset-fullname"] is defined%} + class="form-control danger" + {%else%} + class="form-control" + {%endif%} + required="required" /> + <small class="form-text text-muted"> + <p>A longer, descriptive name for the dataset. The name is meant for use + by humans, and therefore, it should be clear what the dataset contains + from the name.</p> + </small> + </div> + + <div class="form-group"> + <label class="form-label" for="txt-dataset-shortname">Short Name</label> + <input id="txt-dataset-shortname" + name="dataset-shortname" + type="text" + class="form-control" + value="{{original_formdata.get('dataset-shortname') or (population.Name + 'Publish')}}" /> + <small class="form-text text-muted"> + <p>An optional, short name for the dataset. <br /> + If this is not provided, it will default to the value provided for the + <strong>Name</strong> field above.</p></small> + </div> + + <div class="form-group"> + <input type="submit" + class="btn btn-primary" + value="create phenotype dataset" /> + </div> + + </form> +</div> +{%endblock%} + +{%block sidebarcontents%} +{{display_population_card(species, population)}} +{%endblock%} diff --git a/uploader/templates/phenotypes/edit-phenotype.html b/uploader/templates/phenotypes/edit-phenotype.html new file mode 100644 index 0000000..32c903f --- /dev/null +++ b/uploader/templates/phenotypes/edit-phenotype.html @@ -0,0 +1,332 @@ +{%extends "phenotypes/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "populations/macro-display-population-card.html" import display_population_card%} + +{%block title%}Phenotypes{%endblock%} + +{%block pagetitle%}Phenotypes{%endblock%} + +{%block lvl4_breadcrumbs%} +<li {%if activelink=="edit-phenotype"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.phenotypes.edit_phenotype_data', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id, + xref_id=xref_id)}}">View Datasets</a> +</li> +{%endblock%} + +{%block contents%} +{{flash_all_messages()}} + +<div class="row"> + <h2 class="heading">edit phenotype data</h2> + <p>The forms provided in this page help you update the data for the + phenotypes, and the publication information for the phenotype, + respectively.</p> +</div> + +<div class="row"> + <h3 class="subheading">Basic metadata</h3> + <form name="frm-phenotype-basic-metadata" + class="form-horizontal" + method="POST" + action="{{url_for( + 'species.populations.phenotypes.edit_phenotype_data', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id, + xref_id=xref_id)}}"> + <input type="hidden" name="phenotype-id" value="{{phenotype.Id}}" /> + <div class="form-group"> + <label for="txt-pre-publication-description" + class="control-label col-sm-2">Pre-Publication Description</label> + <div class="col-sm-10"> + <input type="text" + id="txt-pre-publication-description" + name="pre-publication-description" + class="form-control" + value="{{phenotype['Pre_publication_description'] or ''}}" /> + </div> + </div> + + <div class="form-group"> + <label for="txt-pre-publication-abbreviation" + class="control-label col-sm-2">Pre-Publication Abbreviation</label> + <div class="col-sm-10"> + <input type="text" + id="txt-pre-publication-abbreviation" + name="pre-publication-abbreviation" + class="form-control" + value="{{phenotype['Pre_publication_abbreviation'] or ''}}" /> + </div> + </div> + + <div class="form-group"> + <label for="txt-post-publication-description" + class="control-label col-sm-2">Post-Publication Description</label> + <div class="col-sm-10"> + <input type="text" + id="txt-post-publication-description" + name="post-publication-description" + class="form-control" + value="{{phenotype['Post_publication_description'] or ''}}" /> + </div> + </div> + + <div class="form-group"> + <label for="txt-post-publication-abbreviation" + class="control-label col-sm-2">Post-Publication Abbreviation</label> + <div class="col-sm-10"> + <input type="text" + id="txt-post-publication-abbreviation" + name="post-publication-abbreviation" + class="form-control" + value="{{phenotype['Post_publication_abbreviation'] or ''}}" /> + </div> + </div> + + <div class="form-group"> + <label for="txt-original-description" + class="control-label col-sm-2">Original Description</label> + <div class="col-sm-10"> + <input type="text" + id="txt-original-description" + name="original-description" + class="form-control" + value="{{phenotype['Original_description'] or ''}}" /> + </div> + </div> + + <div class="form-group"> + <label for="txt-units" + class="control-label col-sm-2">units</label> + <div class="col-sm-10"> + <input type="text" + id="txt-units" + name="units" + class="form-control" + required="required" + value="{{phenotype['Units']}}" /> + </div> + </div> + + <div class="form-group"> + <div class="col-sm-offset-2 col-sm-10"> + <input type="submit" + name="submit" + class="btn btn-primary" + value="update basic metadata"> + </div> + </div> + </form> +</div> + + +<div class="row"> + <h3 class="subheading">phenotype data</h3> + <form id="frm-edit-phenotype-data" + class="form-horizontal" + method="POST" + action="{{url_for( + 'species.populations.phenotypes.edit_phenotype_data', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id, + xref_id=xref_id)}}"> + <div style="max-height: 23.37em;overflow-y: scroll;"> + <table class="table table-striped table-responsive table-form-table"> + <thead style="position: sticky; top: 0;"> + <tr> + <th>#</th> + <th>Sample</th> + <th>Value</th> + {%if population.Family in families_with_se_and_n%} + <th>Standard-Error</th> + <th>Number of Samples</th> + {%endif%} + </tr> + </thead> + + <tbody> + {%for item in phenotype.data%} + <tr> + <td>{{loop.index}}</td> + <td>{{item.StrainName}}</td> + <td> + <input type="text" + name="value-new::{{item.DataId}}::{{item.StrainId}}" + value="{{item.value}}" + class="form-control" /> + <input type="hidden" + name="value-original::{{item.DataId}}::{{item.StrainId}}" + value="{{item.value}}" /></td> + {%if population.Family in families_with_se_and_n%} + <td> + <input type="text" + name="se-new::{{item.DataId}}::{{item.StrainId}}" + value="{{item.error or ''}}" + data-original-value="{{item.error or ''}}" + class="form-control" /> + <input type="hidden" + name="se-original::{{item.DataId}}::{{item.StrainId}}" + value="{{item.error or ''}}" /></td> + <td> + <input type="text" + name="n-new::{{item.DataId}}::{{item.StrainId}}" + value="{{item.count or ''}}" + data-original-value="{{item.count or "-"}}" + class="form-control" /> + <input type="hidden" + name="n-original::{{item.DataId}}::{{item.StrainId}}" + value="{{item.count or ''}}" /></td> + {%endif%} + </tr> + {%endfor%} + </tbody> + </table> + </div> + <div class="form-group"> + <div class="col-sm-offset-2 col-sm-10"> + <input type="submit" + name="submit" + class="btn btn-primary" + value="update data" /> + </div> + </div> + </form> +</div> + + +<div class="row"> + <h3 class="subheading">publication information</h3> + <p>Use the form below to update the publication information for this + phenotype.</p> + <form id="frm-edit-phenotype-pub-data" + class="form-horizontal" + method="POST" + action="#"> + <div class="form-group"> + <label for="txt-pubmed-id" class="control-label col-sm-2">Pubmed ID</label> + <div class="col-sm-10"> + <input id="txt-pubmed-id" name="pubmed-id" type="text" + class="form-control" /> + <span class="form-text text-muted"> + Enter your publication's PubMed ID.</span> + </div> + </div> + + <div class="form-group"> + <label for="txt-publication-authors" class="control-label col-sm-2">Authors</label> + <div class="col-sm-10"> + <input id="txt-publication-authors" name="publication-authors" + type="text" class="form-control" /> + <span class="form-text text-muted"> + Enter the authors.</span> + </div> + </div> + + <div class="form-group"> + <label for="txt-publication-title" class="control-label col-sm-2"> + Publication Title</label> + <div class="col-sm-10"> + <input id="txt-publication-title" name="publication-title" type="text" + class="form-control" /> + <span class="form-text text-muted"> + Enter your publication's title.</span> + </div> + </div> + + <div class="form-group"> + <label for="txt-publication-abstract" class="control-label col-sm-2"> + Publication Abstract</label> + <div class="col-sm-10"> + <textarea id="txt-publication-abstract" name="publication-abstract" + class="form-control" rows="10"></textarea> + <span class="form-text text-muted"> + Enter the abstract for your publication.</span> + </div> + </div> + + <div class="form-group"> + <label for="txt-publication-journal" class="control-label col-sm-2">Journal</label> + <div class="col-sm-10"> + <input id="txt-publication-journal" name="journal" type="text" + class="form-control" /> + <span class="form-text text-muted"> + Enter the name of the journal where your work was published.</span> + </div> + </div> + + <div class="form-group"> + <label for="txt-publication-volume" class="control-label col-sm-2">Volume</label> + <div class="col-sm-10"> + <input id="txt-publication-volume" name="publication-volume" type="text" + class="form-control" /> + <span class="form-text text-muted"> + Enter the volume in the following format …</span> + </div> + </div> + + <div class="form-group"> + <label for="txt-publication-pages" class="control-label col-sm-2">Pages</label> + <div class="col-sm-10"> + <input id="txt-publication-pages" name="publication-pages" type="text" + class="form-control" /> + <span class="form-text text-muted"> + Enter the journal volume where your work was published.</span> + </div> + </div> + + <div class="form-group"> + <label for="select-publication-month" class="control-label col-sm-2"> + Publication Month</label> + <div class="col-sm-10"> + <select id="select-publication-month" name="publication-month" + class="form-control"> + {%for month in monthnames%} + <option value="{{month | lower}}" + {%if current_month | lower == month | lower%} + selected="selected" + {%endif%}>{{month | capitalize}}</option> + {%endfor%} + </select> + <span class="form-text text-muted"> + Select the month when the work was published. + <span class="text-danger"> + This cannot be before, say 1600 and cannot be in the future!</span></span> + </div> + </div> + + <div class="form-group"> + <label for="txt-publication-year" class="control-label col-sm-2">Publication Year</label> + <div class="col-sm-10"> + <input id="txt-publication-year" name="publication-year" type="text" + class="form-control" value="{{current_year}}" /> + <span class="form-text text-muted"> + Enter the year your work was published. + <span class="text-danger"> + This cannot be before, say 1600 and cannot be in the future!</span> + </span> + </div> + </div> + <div class="form-group"> + <div class="col-sm-offset-2 col-sm-10"> + <input type="submit" + name="submit" + class="btn btn-primary not-implemented" + value="update publication" /> + </div> + </div> + </form> +</div> + +{%endblock%} + +{%block sidebarcontents%} +{{display_population_card(species, population)}} +{%endblock%} diff --git a/uploader/templates/phenotypes/index.html b/uploader/templates/phenotypes/index.html new file mode 100644 index 0000000..689c28e --- /dev/null +++ b/uploader/templates/phenotypes/index.html @@ -0,0 +1,21 @@ +{%extends "phenotypes/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "species/macro-select-species.html" import select_species_form%} + +{%block title%}Phenotypes{%endblock%} + +{%block pagetitle%}Phenotypes{%endblock%} + + +{%block contents%} +{{flash_all_messages()}} + +<div class="row"> + {{select_species_form(url_for("species.populations.phenotypes.index"), species)}} +</div> +{%endblock%} + + +{%block javascript%} +<script type="text/javascript" src="/static/js/species.js"></script> +{%endblock%} diff --git a/uploader/templates/phenotypes/job-status.html b/uploader/templates/phenotypes/job-status.html new file mode 100644 index 0000000..12963c1 --- /dev/null +++ b/uploader/templates/phenotypes/job-status.html @@ -0,0 +1,155 @@ +{%extends "phenotypes/base.html"%} +{%from "cli-output.html" import cli_output%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "macro-table-pagination.html" import table_pagination%} +{%from "phenotypes/macro-display-pheno-dataset-card.html" import display_pheno_dataset_card%} + +{%block extrameta%} +{%if job and job.status not in ("success", "completed:success", "error", "completed:error")%} +<meta http-equiv="refresh" content="5" /> +{%endif%} +{%endblock%} + +{%block title%}Phenotypes{%endblock%} + +{%block pagetitle%}Phenotypes{%endblock%} + +{%block lvl4_breadcrumbs%} +<li {%if activelink=="add-phenotypes"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.phenotypes.add_phenotypes', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id)}}">View Datasets</a> +</li> +{%endblock%} + +{%block contents%} + +{%if job%} +<h4 class="subheading">Progress</h4> +<div class="row" style="overflow:scroll;"> + <p><strong>Process Status:</strong> {{job.status}}</p> + {%if metadata%} + <table class="table table-responsive"> + <thead> + <tr> + <th>File</th> + <th>Status</th> + <th>Lines Processed</th> + <th>Total Errors</th> + </tr> + </thead> + + <tbody> + {%for file,meta in metadata.items()%} + <tr> + <td>{{file}}</td> + <td>{{meta.status}}</td> + <td>{{meta.linecount}}</td> + <td>{{meta["total-errors"]}}</td> + </tr> + {%endfor%} + </tbody> + </table> + {%endif%} +</div> + +<div class="row"> + {%if job.status in ("completed:success", "success")%} + <p> + {%if errors | length == 0%} + <a href="{{url_for('species.populations.phenotypes.review_job_data', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id, + job_id=job_id)}}" + class="btn btn-primary" + title="Continue to process data">Continue</a> + {%else%} + <span class="text-muted" + disabled="disabled" + style="border: solid 2px;border-radius: 5px;padding: 0.3em;"> + Cannot continue due to errors. Please fix the errors first. + </span> + {%endif%} + </p> + {%endif%} +</div> + +<h4 class="subheading">Errors</h4> +<div class="row" style="max-height: 20em; overflow: scroll;"> + {%if errors | length == 0 %} + <p class="text-info"> + <span class="glyphicon glyphicon-info-sign"></span> + No errors found so far + </p> + {%else%} + <table class="table table-responsive"> + <thead style="position: sticky; top: 0; background: white;"> + <tr> + <th>File</th> + <th>Row</th> + <th>Column</th> + <th>Value</th> + <th>Message</th> + </tr> + </thead> + + <tbody style="font-size: 0.9em;"> + {%for error in errors%} + <tr> + <td>{{error.filename}}</td> + <td>{{error.rowtitle}}</td> + <td>{{error.coltitle}}</td> + <td>{%if error.cellvalue | length > 25%} + {{error.cellvalue[0:24]}}… + {%else%} + {{error.cellvalue}} + {%endif%} + </td> + <td> + {%if error.message | length > 250 %} + {{error.message[0:249]}}… + {%else%} + {{error.message}} + {%endif%} + </td> + </tr> + {%endfor%} + </tbody> + </table> + {%endif%} +</div> + +<div class="row"> + {{cli_output(job, "stdout")}} +</div> + +<div class="row"> + {{cli_output(job, "stderr")}} +</div> + +{%else%} +<div class="row"> + <h3 class="text-danger">No Such Job</h3> + <p>Could not find a job with the ID: {{job_id}}</p> + <p> + Please go back to + <a href="{{url_for('species.populations.phenotypes.view_dataset', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id)}}" + title="'{{dataset.Name}}' dataset page"> + the '{{dataset.Name}}' dataset page</a> + to upload new phenotypes or edit existing ones.</p> +</div> +{%endif%} +{%endblock%} + +{%block sidebarcontents%} +{{display_pheno_dataset_card(species, population, dataset)}} +{%endblock%} diff --git a/uploader/templates/phenotypes/list-datasets.html b/uploader/templates/phenotypes/list-datasets.html new file mode 100644 index 0000000..2cf2c7f --- /dev/null +++ b/uploader/templates/phenotypes/list-datasets.html @@ -0,0 +1,68 @@ +{%extends "phenotypes/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "populations/macro-display-population-card.html" import display_population_card%} + +{%block title%}Phenotypes{%endblock%} + +{%block pagetitle%}Phenotypes{%endblock%} + +{%block lvl4_breadcrumbs%} +<li {%if activelink=="list-datasets"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.phenotypes.list_datasets', + species_id=species.SpeciesId, + population_id=population.Id)}}">List Datasets</a> +</li> +{%endblock%} + +{%block contents%} +{{flash_all_messages()}} + +<div class="row"> + {%if datasets | length > 0%} + <p>The dataset(s) available for this population is/are:</p> + + <table class="table"> + <thead> + <tr> + <th>Name</th> + <th>Full Name</th> + <th>Short Name</th> + </tr> + </thead> + + <tbody> + {%for dataset in datasets%} + <tr> + <td><a href="{{url_for('species.populations.phenotypes.view_dataset', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id)}}">{{dataset.Name}}</a></td> + <td>{{dataset.FullName}}</td> + <td>{{dataset.ShortName}}</td> + </tr> + {%endfor%} + </tbody> + </table> + {%else%} + <p>Phenotypes need to go into a dataset. We do not currently have a dataset + for species <strong>'{{species["FullName"]}} ({{species["Name"]}})'</strong> + phenotypes.</p> + + <p>Do, please, create a new dataset by clicking on the "Create Dataset" button + below and following the prompts/instructions.</p> + <p><a href="{{url_for('species.populations.phenotypes.create_dataset', + species_id=species.SpeciesId, + population_id=population.Id)}}" + class="btn btn-primary" + title="Create a new phenotype dataset.">create dataset</a></p> + {%endif%} +</div> +{%endblock%} + +{%block sidebarcontents%} +{{display_population_card(species, population)}} +{%endblock%} diff --git a/uploader/templates/phenotypes/load-phenotypes-success.html b/uploader/templates/phenotypes/load-phenotypes-success.html new file mode 100644 index 0000000..645be16 --- /dev/null +++ b/uploader/templates/phenotypes/load-phenotypes-success.html @@ -0,0 +1,42 @@ +{%extends "phenotypes/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "macro-table-pagination.html" import table_pagination%} +{%from "phenotypes/macro-display-pheno-dataset-card.html" import display_pheno_dataset_card%} + +{%block title%}Phenotypes{%endblock%} + +{%block pagetitle%}Phenotypes{%endblock%} + +{%block lvl4_breadcrumbs%} +<li {%if activelink=="load-phenotypes-success"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.phenotypes.add_phenotypes', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id)}}">Add Phenotypes</a> +</li> +{%endblock%} + +{%block contents%} +<div class="row"> + <p>You have successfully loaded + <!-- maybe indicate the number of phenotypes here? -->your + new phenotypes into the database.</p> + <!-- TODO: Maybe notify user that they have sole access. --> + <!-- TODO: Maybe provide a link to go to GeneNetwork to view the data. --> + <p>View your data + <a href="{{search_page_uri}}" + target="_blank">on GeneNetwork2</a>. + You might need to login to GeneNetwork2 to view specific traits.</p> +</div> +{%endblock%} + +{%block sidebarcontents%} +{{display_pheno_dataset_card(species, population, dataset)}} +{%endblock%} + + +{%block more_javascript%}{%endblock%} diff --git a/uploader/templates/phenotypes/macro-display-pheno-dataset-card.html b/uploader/templates/phenotypes/macro-display-pheno-dataset-card.html new file mode 100644 index 0000000..11b108b --- /dev/null +++ b/uploader/templates/phenotypes/macro-display-pheno-dataset-card.html @@ -0,0 +1,31 @@ +{%from "populations/macro-display-population-card.html" import display_population_card%} + +{%macro display_pheno_dataset_card(species, population, dataset)%} +{{display_population_card(species, population)}} + +<div class="card"> + <div class="card-body"> + <h5 class="card-title">Phenotypes' Dataset</h5> + <div class="card-text"> + <table class="table"> + <tbody> + <tr> + <td>Name</td> + <td>{{dataset.Name}}</td> + </tr> + + <tr> + <td>Full Name</td> + <td>{{dataset.FullName}}</td> + </tr> + + <tr> + <td>Short Name</td> + <td>{{dataset.ShortName}}</td> + </tr> + </tbody> + </table> + </div> + </div> +</div> +{%endmacro%} diff --git a/uploader/templates/phenotypes/macro-display-preview-table.html b/uploader/templates/phenotypes/macro-display-preview-table.html new file mode 100644 index 0000000..5a4c422 --- /dev/null +++ b/uploader/templates/phenotypes/macro-display-preview-table.html @@ -0,0 +1,19 @@ +{%macro display_preview_table(tableid, filetype)%} +<div class="card"> + <div class="card-body"> + <h5 class="card-title">{{filetype | title}}: File Preview</h5> + <div class="card-text" style="overflow: scroll;"> + <table id="{{tableid}}" class="table table-condensed table-responsive"> + <thead> + <tr> + </tr> + <tbody> + <tr> + <td class="data-row-template text-info"></td> + </tr> + </tbody> + </table> + </div> + </div> +</div> +{%endmacro%} diff --git a/uploader/templates/phenotypes/macro-display-resumable-elements.html b/uploader/templates/phenotypes/macro-display-resumable-elements.html new file mode 100644 index 0000000..ed14ea5 --- /dev/null +++ b/uploader/templates/phenotypes/macro-display-resumable-elements.html @@ -0,0 +1,60 @@ +{%macro display_resumable_elements(id, title, help)%} +<div id="{{id}}" + class="resumable-elements visually-hidden" + style="background:#D4D4EE;border-radius: 5px;;padding: 1em;border-left: solid #B2B2CC 1px;border-bottom: solid #B2B2CC 2px;margin-top:0.3em;"> + <strong style="line-height: 1.2em;">{{title | title}}</strong> + + <span class="form-text text-muted">{{help | safe}}</span> + + <div id="{{id}}-selected-files" + class="resumable-selected-files" + style="display:flex;flex-direction:row;flex-wrap: wrap;justify-content:space-around;gap:10px 20px;"> + <div class="panel panel-info file-display-template visually-hidden"> + <div class="panel-heading filename">The Filename Goes Here!</div> + <div class="panel-body"> + <ul> + <li> + <strong>Name</strong>: + <span class="filename">the file's name</span></li> + + <li><strong>Size</strong>: <span class="filesize">0 MB</span></li> + + <li> + <strong>Unique Identifier</strong>: + <span class="fileuniqueid">brrr</span></li> + + <li> + <strong>Mime</strong>: + <span class="filemimetype">text/csv</span></li> + </ul> + </div> + </div> + </div> + + <a id="{{id}}-browse-button" + class="resumable-browse-button btn btn-info" + href="#{{id}}" + style="margin-left: 80%;">Browse</a> + + <div id="{{id}}-progress-bar" class="progress visually-hidden"> + <div class="progress-bar" + role="progress-bar" + aria-valuenow="60" + aria-valuemin="0" + aria-valuemax="100" + style="width: 0%;"> + Uploading: 60% + </div> + </div> + + <div id="{{id}}-cancel-resume-buttons"> + <a id="{{id}}-resume-button" + class="resumable-resume-button btn btn-info visually-hidden" + href="#">resume upload</a> + + <a id="{{id}}-cancel-button" + class="resumable-cancel-button btn btn-danger visually-hidden" + href="#">cancel upload</a> + </div> +</div> +{%endmacro%} diff --git a/uploader/templates/phenotypes/review-job-data.html b/uploader/templates/phenotypes/review-job-data.html new file mode 100644 index 0000000..859df74 --- /dev/null +++ b/uploader/templates/phenotypes/review-job-data.html @@ -0,0 +1,125 @@ +{%extends "phenotypes/base.html"%} +{%from "cli-output.html" import cli_output%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "macro-table-pagination.html" import table_pagination%} +{%from "phenotypes/macro-display-pheno-dataset-card.html" import display_pheno_dataset_card%} + +{%block extrameta%} +{%if not job%} +<meta http-equiv="refresh" + content="20; url={{url_for('species.populations.phenotypes.view_dataset', species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id)}}" /> +{%endif%} +{%endblock%} + +{%block title%}Phenotypes{%endblock%} + +{%block pagetitle%}Phenotypes{%endblock%} + +{%block lvl4_breadcrumbs%} +<li {%if activelink=="add-phenotypes"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.phenotypes.add_phenotypes', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id)}}">View Datasets</a> +</li> +{%endblock%} + +{%block contents%} + +{%if job%} +<div class="row"> + <h3 class="heading">Data Review</h3> + <p class="text-info"><strong> + The data has <em>NOT</em> been added/saved yet. Review the details below + and click "Continue" to save the data.</strong></p> + <p>The “<strong>{{dataset.FullName}}</strong>” dataset from the + “<strong>{{population.FullName}}</strong>” population of the + species “<strong>{{species.SpeciesName}} ({{species.FullName}})</strong>” + will be updated as follows:</p> + + <ul> + {%if publication%} + <li>All {{summary.get("pheno", {}).get("total-data-rows", "0")}} phenotypes + are linked to the following publication: + <ul> + <li><strong>Publication Title:</strong> + {{publication.Title or "—"}}</li> + <li><strong>Author(s):</strong> + {{publication.Authors or "—"}}</li> + </ul> + </li> + {%endif%} + {%for ftype in ("phenocovar", "pheno", "phenose", "phenonum")%} + {%if summary.get(ftype, False)%} + <li>A total of {{summary[ftype]["number-of-files"]}} files will be processed + adding {%if ftype == "phenocovar"%}(possibly){%endif%} + {{summary[ftype]["total-data-rows"]}} new + {%if ftype == "phenocovar"%} + phenotypes + {%else%} + {{summary[ftype]["description"]}} rows + {%endif%} + to the database. + </li> + {%endif%} + {%endfor%} + </ul> + + <form id="frm-review-phenotype-data" + method="POST" + action="{{url_for('species.populations.phenotypes.load_data_to_database', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id)}}"> + <input type="hidden" name="data-qc-job-id" value="{{job.jobid}}" /> + <input type="submit" + value="continue" + class="btn btn-primary" /> + </form> +</div> +{%else%} +<div class="row"> + <h4 class="subheading">Invalid Job</h3> + <p class="text-danger"> + Could not find a job with the ID: <strong>{{job_id}}.</p> + <p>You will be redirected in + <span id="countdown-element" class="text-info">20</span> second(s)</p> + <p class="text-muted"> + <small> + If you are not redirected, please + <a href="{{url_for( + 'species.populations.phenotypes.view_dataset', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id)}}">click here</a> to continue + </small> + </p> +</div> +{%endif%} +{%endblock%} + +{%block sidebarcontents%} +{{display_pheno_dataset_card(species, population, dataset)}} +{%endblock%} + + +{%block javascript%} +<script type="text/javascript"> + $(document).ready(function() { + var countdown = 20; + var countdown_element = $("#countdown-element"); + if(countdown_element.length === 1) { + intv = window.setInterval(function() { + countdown = countdown - 1; + countdown_element.html(countdown); + }, 1000); + } + }); +</script> +{%endblock%} diff --git a/uploader/templates/phenotypes/select-population.html b/uploader/templates/phenotypes/select-population.html new file mode 100644 index 0000000..48c19b1 --- /dev/null +++ b/uploader/templates/phenotypes/select-population.html @@ -0,0 +1,26 @@ +{%extends "phenotypes/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "species/macro-display-species-card.html" import display_species_card%} +{%from "populations/macro-select-population.html" import select_population_form%} + +{%block title%}Phenotypes{%endblock%} + +{%block pagetitle%}Phenotypes{%endblock%} + + +{%block contents%} +{{flash_all_messages()}} + + +<div class="row"> + {{select_population_form(url_for("species.populations.phenotypes.select_population", species_id=species.SpeciesId), species, populations)}} +</div> +{%endblock%} + +{%block sidebarcontents%} +{{display_species_card(species)}} +{%endblock%} + +{%block javascript%} +<script type="text/javascript" src="/static/js/populations.js"></script> +{%endblock%} diff --git a/uploader/templates/phenotypes/view-dataset.html b/uploader/templates/phenotypes/view-dataset.html new file mode 100644 index 0000000..21563d6 --- /dev/null +++ b/uploader/templates/phenotypes/view-dataset.html @@ -0,0 +1,244 @@ +{%extends "phenotypes/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "macro-table-pagination.html" import table_pagination%} +{%from "populations/macro-display-population-card.html" import display_population_card%} + +{%block title%}Phenotypes{%endblock%} + +{%block pagetitle%}Phenotypes{%endblock%} + +{%block lvl4_breadcrumbs%} +<li {%if activelink=="view-dataset"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.phenotypes.view_dataset', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id)}}">View</a> +</li> +{%endblock%} + +{%block contents%} +{{flash_all_messages()}} + +<div class="row"> + <p>The basic dataset details are:</p> + + <table class="table"> + <thead> + <tr> + <th>Name</th> + <th>Full Name</th> + <th>Short Name</th> + </tr> + </thead> + + <tbody> + <tr> + <td>{{dataset.Name}}</td> + <td>{{dataset.FullName}}</td> + <td>{{dataset.ShortName}}</td> + </tr> + </tbody> + </table> +</div> + +<div class="row"> + <p><a href="{{url_for('species.populations.phenotypes.add_phenotypes', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id)}}" + title="Add a bunch of phenotypes" + class="btn btn-primary">Add phenotypes</a></p> +</div> + +<div class="row"> + <h2>Phenotype Data</h2> + + <p>Click on any of the phenotypes in the table below to view and edit that + phenotype's data.</p> + <p>Use the search to filter through all the phenotypes and find specific + phenotypes of interest.</p> +</div> + + +<div class="row"> + + <table id="tbl-phenotypes-list" class="table compact stripe cell-border"> + <thead> + <tr> + <th></th> + <th>Index</th> + <th>Record</th> + <th>Description</th> + </tr> + </thead> + + <tbody></tbody> + </table> +</div> +{%endblock%} + +{%block sidebarcontents%} +{{display_population_card(species, population)}} +{%endblock%} + + +{%block javascript%} +<script type="text/javascript"> + $(function() { + var species_id = {{species.SpeciesId}}; + var population_id = {{population.Id}}; + var dataset_id = {{dataset.Id}}; + var dataset_name = "{{dataset.Name}}"; + var data = {{phenotypes | tojson}}; + + var dtPhenotypesList = buildDataTable( + "#tbl-phenotypes-list", + data, + [ + { + data: function(pheno) { + return `<input type="checkbox" name="selected-phenotypes" ` + + `id="chk-selected-phenotypes-${pheno.InbredSetCode}_${pheno.xref_id}" ` + + `value="${pheno.InbredSetCode}_${pheno.xref_id}" ` + + `class="chk-row-select" />` + } + }, + {data: "sequence_number"}, + { + data: function(pheno, type, set, meta) { + var spcs_id = {{species.SpeciesId}}; + var pop_id = {{population.Id}}; + var dtst_id = {{dataset.Id}}; + return `<a href="/species/${spcs_id}` + + `/populations/${pop_id}` + + `/phenotypes/datasets/${dtst_id}` + + `/phenotype/${pheno.xref_id}` + + `" target="_blank">` + + `${pheno.InbredSetCode}_${pheno.xref_id}` + + `</a>`; + } + }, + { + data: function(pheno) { + return (pheno.Post_publication_description || + pheno.Original_description || + pheno.Pre_publication_description); + } + } + ], + { + select: "multi+shift", + layout: { + top2: { + buttons: [ + { + extend: "selectAll", + className: "btn btn-info", + titleAttr: "Click to select ALL records in the table." + }, + { + extend: "selectNone", + className: "btn btn-info", + titleAttr: "Click to deselect ANY selected record(s) in the table." + }, + { + text: "Bulk Edit (Download Data)", + className: "btn btn-info btn-bulk-edit", + titleAttr: "Click to download data for editing.", + action: (event, dt, node, config) => { + var phenoids = []; + var selected = dt.rows({selected: true, page: "all"}).data(); + for(var idx = 0; idx < selected.length; idx++) { + phenoids.push({ + phenotype_id: selected[idx].Id, + xref_id: selected[idx].xref_id + }); + } + if(phenoids.length == 0) { + alert("No record selected. Nothing to do!"); + return false; + } + + $(".btn-bulk-edit").prop("disabled", true); + $(".btn-bulk-edit").addClass("d-none"); + var spinner = $( + "<div id='bulk-edit-spinner' class='spinner-grow text-info'>"); + spinner_content = $( + "<span class='visually-hidden'>"); + spinner_content.html( + "Downloading data …"); + spinner.append(spinner_content) + $(".btn-bulk-edit").parent().append( + spinner); + + $.ajax( + (`/species/${species_id}/populations/` + + `${population_id}/phenotypes/datasets/` + + `${dataset_id}/edit-download`), + { + method: "POST", + data: JSON.stringify(phenoids), + xhrFields: { + responseType: "blob" + }, + success: (data, textStatus, jqXHR) => { + var link = document.createElement("a"); + uri = window.URL.createObjectURL(data); + link.href = uri; + link.download = `${dataset_name}_data.tsv`; + + document.body.appendChild(link); + link.click(); + window.URL.revokeObjectURL(uri); + link.remove(); + }, + error: (jQXHR, textStatus, errorThrown) => { + console.log("Experienced an error: ", textStatus); + console.log("The ERROR: ", errorThrown); + }, + complete: (jqXHR, textStatus) => { + $("#bulk-edit-spinner").remove(); + $(".btn-bulk-edit").removeClass( + "d-none"); + $(".btn-bulk-edit").prop( + "disabled", false); + }, + contentType: "application/json" + }); + } + }, + { + text: "Bulk Edit (Upload Data)", + className: "btn btn-info btn-bulk-edit", + titleAttr: "Click to upload edited data you got by clicking the `Bulk Edit (Download Data)` button.", + action: (event, dt, node, config) => { + window.location.assign( + `${window.location.protocol}//` + + `${window.location.host}` + + `/species/${species_id}` + + `/populations/${population_id}` + + `/phenotypes/datasets/${dataset_id}` + + `/edit-upload`) + } + } + ] + }, + top1Start: { + pageLength: { + text: "Show _MENU_ of _TOTAL_" + } + }, + topStart: "info", + top1End: null + }, + rowId: function(pheno) { + return `${pheno.InbredSetCode}_${pheno.xref_id}`; + } + }); + }); +</script> +{%endblock%} diff --git a/uploader/templates/phenotypes/view-phenotype.html b/uploader/templates/phenotypes/view-phenotype.html new file mode 100644 index 0000000..21ac501 --- /dev/null +++ b/uploader/templates/phenotypes/view-phenotype.html @@ -0,0 +1,135 @@ +{%extends "phenotypes/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "populations/macro-display-population-card.html" import display_population_card%} + +{%block title%}Phenotypes{%endblock%} + +{%block pagetitle%}Phenotypes{%endblock%} + +{%block lvl4_breadcrumbs%} +<li {%if activelink=="view-phenotype"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.phenotypes.view_phenotype', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id, + xref_id=xref_id)}}">View Phenotype</a> +</li> +{%endblock%} + +{%block contents%} +{{flash_all_messages()}} + +<div class="row"> + <div class="panel panel-default"> + <div class="panel-heading"><strong>Basic Phenotype Details</strong></div> + + <table class="table"> + <tbody> + <tr> + <td><strong>Phenotype</strong></td> + <td>{{phenotype.Post_publication_description or phenotype.Pre_publication_abbreviation or phenotype.Original_description}} + </tr> + <tr> + <td><strong>Database</strong></td> + <td>{{dataset.FullName}}</td> + </tr> + <tr> + <td><strong>Units</strong></td> + <td>{{phenotype.Units}}</td> + </tr> + {%for key,value in publish_data.items()%} + <tr> + <td><strong>{{key}}</strong></td> + <td>{{value}}</td> + </tr> + {%else%} + <tr> + <td colspan="2" class="text-muted"> + <span class="glyphicon glyphicon-exclamation-sign"></span> + No publication data found. + </td> + </tr> + {%endfor%} + </tbody> + </table> + </div> +</div> + +{%if "group:resource:edit-resource" in privileges +or "group:resource:delete-resource" in privileges%} +<div class="row"> + <div class="btn-group btn-group-justified"> + <div class="btn-group"> + {%if "group:resource:edit-resource" in privileges%} + <a href="{{url_for('species.populations.phenotypes.edit_phenotype_data', + species_id=species.SpeciesId, + population_id=population.Id, + dataset_id=dataset.Id, + xref_id=xref_id)}}" + title="Edit the values for the phenotype. This is meant to be used when you need to update only a few values." + class="btn btn-primary">Edit</a> + {%endif%} + </div> + <div class="btn-group"></div> + <div class="btn-group"> + {%if "group:resource:delete-resource" in privileges%} + <a href="#" + title="Delete the entire phenotype. This is useful when you need to change data for most or all of the fields for this phenotype." + class="btn btn-danger not-implemented" + disabled="disabled">delete</a> + {%endif%} + </div> + </div> +</div> +{%endif%} + +<div class="row"> + <div class="panel panel-default"> + <div class="panel-heading"><strong>Phenotype Data</strong></div> + {%if "group:resource:view-resource" in privileges%} + <table class="table"> + <thead> + <tr> + <th>#</th> + <th>Sample</th> + <th>Value</th> + {%if has_se%} + <th>SE</th> + <th>N</th> + {%endif%} + </tr> + </thead> + + <tbody> + {%for item in phenotype.data%} + <tr> + <td>{{loop.index}}</td> + <td>{{item.StrainName}}</td> + <td>{{item.value}}</td> + {%if has_se%} + <td>{{item.error or "-"}}</td> + <td>{{item.count or "-"}}</td> + {%endif%} + </tr> + {%endfor%} + </tbody> + </table> + {%else%} + <p class="text-danger"> + <span class="glyphicon glyphicon-exclamation-sign"></span> + You do not currently have privileges to view this phenotype in greater + detail. + </p> + {%endif%} + </div> +</div> + +{%endblock%} + +{%block sidebarcontents%} +{{display_population_card(species, population)}} +{%endblock%} diff --git a/uploader/templates/platforms/base.html b/uploader/templates/platforms/base.html new file mode 100644 index 0000000..dac965f --- /dev/null +++ b/uploader/templates/platforms/base.html @@ -0,0 +1,13 @@ +{%extends "species/base.html"%} + +{%block lvl3_breadcrumbs%} +<li {%if activelink=="platforms"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.platforms.index')}}"> + Sequencing Platforms</a> +</li> +{%block lvl4_breadcrumbs%}{%endblock%} +{%endblock%} diff --git a/uploader/templates/platforms/create-platform.html b/uploader/templates/platforms/create-platform.html new file mode 100644 index 0000000..0866d5e --- /dev/null +++ b/uploader/templates/platforms/create-platform.html @@ -0,0 +1,124 @@ +{%extends "platforms/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "species/macro-display-species-card.html" import display_species_card%} + +{%block title%}Platforms — Create Platforms{%endblock%} + +{%block pagetitle%}Platforms — Create Platforms{%endblock%} + +{%block lvl3_breadcrumbs%} +<li {%if activelink=="create-platform"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.platforms.create_platform', + species_id=species.SpeciesId)}}">create platform</a> +</li> +{%endblock%} + +{%block contents%} +{{flash_all_messages()}} + +<div class="row"> + <h2>Create New Platform</h2> + + <p>You can create a new genetic sequencing platform below.</p> +</div> + +<div class="row"> + <form id="frm-create-platform" + method="POST" + action="{{url_for('species.platforms.create_platform', + species_id=species.SpeciesId)}}"> + + <div class="form-group"> + <label for="txt-geo-platform" class="form-label">GEO Platform</label> + <input type="text" + id="txt-geo-platform" + name="geo-platform" + required="required" + class="form-control" /> + <small class="form-text text-muted"> + <p>This is the platform's + <a href="https://www.ncbi.nlm.nih.gov/geo/browse/?view=platforms&tax={{species.TaxonomyId}}" + title="Platforms for '{{species.FullName}}' on NCBI"> + accession value on NCBI</a>. If you do not know the value, click the + link and search on NCBI for species '{{species.FullName}}'.</p></small> + </div> + + <div class="form-group"> + <label for="txt-platform-name" class="form-label">Platform Name</label> + <input type="text" + id="txt-platform-name" + name="platform-name" + required="required" + class="form-control" /> + <small class="form-text text-muted"> + <p>This is name of the genetic sequencing platform.</p></small> + </div> + + <div class="form-group"> + <label for="txt-platform-shortname" class="form-label"> + Platform Short Name</label> + <input type="text" + id="txt-platform-shortname" + name="platform-shortname" + required="required" + class="form-control" /> + <small class="form-text text-muted"> + <p>Use the following conventions for this field: + <ol> + <li>Start with a 4-letter vendor code, e.g. "Affy" for "Affymetrix", "Illu" for "Illumina", etc.</li> + <li>Append an underscore to the 4-letter vendor code</li> + <li>Use the name of the array given by the vendor, e.g. U74AV2, MOE430A, etc.</li> + </ol> + </p> + </small> + </div> + + <div class="form-group"> + <label for="txt-platform-title" class="form-label">Platform Title</label> + <input type="text" + id="txt-platform-title" + name="platform-title" + required="required" + class="form-control" /> + <small class="form-text text-muted"> + <p>The full platform title. Sometimes, this is the same as the Platform + Name above.</p></small> + </div> + + <div class="form-group"> + <label for="txt-go-tree-value" class="form-label">GO Tree Value</label> + <input type="text" + id="txt-go-tree-value" + name="go-tree-value" + class="form-control" /> + <small class="form-text text-muted"> + <p>This is a Chip identification value useful for analysis with the + <strong> + <a href="https://www.geneweaver.org/" + title="Go to the GeneWeaver site." + target="_blank">GeneWeaver</a></strong> + and + <strong> + <a href="https://www.webgestalt.org/" + title="Go to the WEB-based GEne SeT AnaLysis Toolkit site." + target="_blank">WebGestalt</a></strong> + tools.<br /> + This can be left blank for custom platforms.</p></small> + </div> + + <div class="form-group"> + <input type="submit" + value="create new platform" + class="btn btn-primary" /> + </div> + </form> +</div> +{%endblock%} + +{%block sidebarcontents%} +{{display_species_card(species)}} +{%endblock%} diff --git a/uploader/templates/platforms/index.html b/uploader/templates/platforms/index.html new file mode 100644 index 0000000..555b444 --- /dev/null +++ b/uploader/templates/platforms/index.html @@ -0,0 +1,25 @@ +{%extends "platforms/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "species/macro-select-species.html" import select_species_form%} + +{%block title%}Platforms{%endblock%} + +{%block pagetitle%}Platforms{%endblock%} + + +{%block contents%} +{{flash_all_messages()}} + +<div class="row"> + <p>In this section, you will be able to view and manage the sequencing + platforms that are currently supported by GeneNetwork.</p> +</div> + +<div class="row"> + {{select_species_form(url_for("species.platforms.index"), species)}} +</div> +{%endblock%} + +{%block javascript%} +<script type="text/javascript" src="/static/js/species.js"></script> +{%endblock%} diff --git a/uploader/templates/platforms/list-platforms.html b/uploader/templates/platforms/list-platforms.html new file mode 100644 index 0000000..a6bcfdc --- /dev/null +++ b/uploader/templates/platforms/list-platforms.html @@ -0,0 +1,93 @@ +{%extends "platforms/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "species/macro-display-species-card.html" import display_species_card%} + +{%block title%}Platforms — List Platforms{%endblock%} + +{%block pagetitle%}Platforms — List Platforms{%endblock%} + + +{%block contents%} +{{flash_all_messages()}} + +<div class="row"> + <p>View the list of the genetic sequencing platforms that are currently + supported by GeneNetwork.</p> + <p>If you cannot find the platform you wish to use, you can add it by clicking + the "New Platform" button below.</p> + <p><a href="{{url_for('species.platforms.create_platform', + species_id=species.SpeciesId)}}" + title="Create a new genetic sequencing platform for species {{species.FullName}}" + class="btn btn-primary">Create Platform</a></p> +</div> + +<div class="row"> + <h2>Supported Platforms</h2> + {%if platforms is defined and platforms | length > 0%} + <p>There are {{total_platforms}} platforms supported by GeneNetwork</p> + + <div class="row"> + <div class="col-md-2" style="text-align: start;"> + {%if start_from > 0%} + <a href="{{url_for('species.platforms.list_platforms', + species_id=species.SpeciesId, + start_from=start_from-count, + count=count)}}"> + <span class="glyphicon glyphicon-backward"></span> + Previous + </a> + {%endif%} + </div> + <div class="col-md-8" style="text-align: center;"> + Displaying platforms {{start_from+1}} to {{start_from+count if start_from+count < total_platforms else total_platforms}} of + {{total_platforms}} + </div> + <div class="col-md-2" style="text-align: end;"> + {%if start_from + count < total_platforms%} + <a href="{{url_for('species.platforms.list_platforms', + species_id=species.SpeciesId, + start_from=start_from+count, + count=count)}}"> + Next + <span class="glyphicon glyphicon-forward"></span> + </a> + {%endif%} + </div> + </div> + + <table class="table"> + <thead> + <tr> + <th></th> + <th>Platform Name</th> + <th><a href="https://www.ncbi.nlm.nih.gov/geo/browse/?view=platforms&tax={{species.TaxonomyId}}" + title="Gene Expression Omnibus: Platforms section" + target="_blank">GEO Platform</a></th> + <th>Title</th> + </tr> + </thead> + + <tbody> + {%for platform in platforms%} + <tr> + <td>{{platform.sequence_number}}</td> + <td>{{platform.GeneChipName}}</td> + <td><a href="https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc={{platform.GeoPlatform}}" + title="View platform on the Gene Expression Omnibus" + target="_blank">{{platform.GeoPlatform}}</a></td> + <td>{{platform.Title}}</td> + </tr> + {%endfor%} + </tbody> + </table> + {%else%} + <p class="text-warning"> + <span class="glyphicon glyphicon-exclamation-sign"></span> + There are no platforms supported at this time!</p> + {%endif%} +</div> +{%endblock%} + +{%block sidebarcontents%} +{{display_species_card(species)}} +{%endblock%} diff --git a/uploader/templates/populations/base.html b/uploader/templates/populations/base.html new file mode 100644 index 0000000..9db8083 --- /dev/null +++ b/uploader/templates/populations/base.html @@ -0,0 +1,18 @@ +{%extends "species/base.html"%} + +{%block lvl2_breadcrumbs%} +<li {%if activelink=="populations"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + {%if population is mapping%} + <a href="{{url_for('species.populations.view_population', + species_id=species.SpeciesId, + population_id=population.Id)}}">{{population.Name}}</a> + {%else%} + <a href="{{url_for('species.populations.index')}}">Populations</a> + {%endif%} +</li> +{%block lvl3_breadcrumbs%}{%endblock%} +{%endblock%} diff --git a/uploader/templates/populations/create-population.html b/uploader/templates/populations/create-population.html new file mode 100644 index 0000000..c0c4f45 --- /dev/null +++ b/uploader/templates/populations/create-population.html @@ -0,0 +1,258 @@ +{%extends "populations/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "species/macro-select-species.html" import select_species_form%} +{%from "species/macro-display-species-card.html" import display_species_card%} + +{%block title%}Create Population{%endblock%} + +{%block pagetitle%}Create Population{%endblock%} + +{%block lvl3_breadcrumbs%} +<li {%if activelink=="create-population"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.create_population', + species_id=species.SpeciesId)}}">create population</a> +</li> +{%endblock%} + + +{%block contents%} +<div class="row"> + <p>The population is the next hierarchical node under Species. Data is grouped under a specific population, under a particular species.</p> + <p> + This page enables you to create a new population, in the case that you + cannot find the population you want in the + <a + href="{{url_for('species.populations.list_species_populations', + species_id=species.SpeciesId)}}" + title="Population for species '{{species.FullName}}'."> + list of species populations + </a> + </p> +</div> + +<div class="row"> + <form method="POST" + action="{{url_for('species.populations.create_population', + species_id=species.SpeciesId, + return_to=return_to)}}"> + + <legend>Create Population</legend> + + {{flash_all_messages()}} + + <input type="hidden" name="return_to" value="{{return_to}}"> + + <div {%if errors.population_fullname%} + class="form-group has-error" + {%else%} + class="form-group" + {%endif%}> + <label for="txt-population-fullname" class="form-label">Full Name</label> + {%if errors.population_fullname%} + <small class="form-text text-danger">{{errors.population_fullname}}</small> + {%endif%} + <input type="text" + id="txt-population-fullname" + name="population_fullname" + required="required" + minLength="3" + maxLength="100" + value="{{error_values.population_fullname or ''}}" + class="form-control" /> + <small class="form-text text-muted"> + <p> + This is a descriptive name for your population — useful for + humans. + </p> + </small> + </div> + + <div {%if errors.population_name%} + class="form-group has-error" + {%else%} + class="form-group" + {%endif%}> + <label for="txt-population-name" class="form-label">Name</label> + {%if errors.population_name%} + <small class="form-text text-danger">{{errors.population_name}}</small> + {%endif%} + <input type="text" + id="txt-population-name" + name="population_name" + required="required" + minLength="3" + maxLength="30" + value="{{error_values.population_name or ''}}" + class="form-control" /> + <small class="form-text text-muted"> + <p> + This is a short representative, but constrained name for your + population. + <br /> + The field will only accept letters ('A-Za-z'), numbers (0-9), hyphens + and underscores. Any other character will cause the name to be + rejected. + </p> + </small> + </div> + + <div class="form-group"> + <label for="txt-population-code" class="form-label">Population Code</label> + <input type="text" + id="txt-population-code" + name="population_code" + maxLength="5" + minLength="3" + value="{{error_values.population_code or ''}}" + class="form-control" /> + <small class="form-text text-muted"> + <p class="form-text text-muted"> + This is a 3-character code for your population, that is prepended to + the phenotype identifiers. e.g. For the "BXD Family" population, the + code is "BXD" and therefore, the phenotype identifiers for the + population look like the following examples: <em>BXD_10148</em>, + <em>BXD_10180</em>, <em>BXD_10197</em>, etc. + </p> + </small> + </div> + + <div {%if errors.population_description%} + class="form-group has-error" + {%else%} + class="form-group" + {%endif%}> + <label for="txt-population-description" class="form-label"> + Description + </label> + {%if errors.population_description%} + <small class="form-text text-danger">{{errors.population_description}}</small> + {%endif%} + <textarea + id="txt-population-description" + name="population_description" + required="required" + class="form-control" + rows="5">{{error_values.population_description or ''}}</textarea> + <small class="form-text text-muted"> + <p> + This is a more detailed description for your population. This is + useful to communicate with other researchers some details regarding + your population, and what its about. + <br /> + Put, here, anything that describes your population but does not go + cleanly under metadata. + </p> + </small> + </div> + + <div {%if errors.population_family%} + class="form-group has-error" + {%else%} + class="form-group" + {%endif%}> + <label for="select-population-family" class="form-label">Family</label> + <select id="select-population-family" + name="population_family" + class="form-control" + required="required"> + <option value="">Please select a family</option> + {%for family in families%} + <option value="{{family}}" + {%if error_values.population_family == family%} + selected="selected" + {%endif%}>{{family}}</option> + {%endfor%} + </select> + <small class="form-text text-muted"> + <p> + This is a rough grouping of the populations in GeneNetwork into lists + of common types of populations. + </p> + </small> + </div> + + <div {%if errors.population_mapping_method_id%} + class="form-group has-error" + {%else%} + class="form-group" + {%endif%}> + <label for="select-population-mapping-methods" + class="form-label">Mapping Methods</label> + + <select id="select-population-mapping-methods" + name="population_mapping_method_id" + class="form-control" + required="required"> + <option value="">Select appropriate mapping methods</option> + {%for mmethod in mapping_methods%} + <option value="{{mmethod.id}}" + {%if error_values.population_mapping_method_id == mmethod.id%} + selected="selected" + {%endif%}>{{mmethod.value}}</option> + {%endfor%} + </select> + + <small class="form-text text-muted"> + <p>Select the mapping methods that your population will support.</p> + </small> + </div> + + <div {%if errors.population_genetic_type%} + class="form-group has-error" + {%else%} + class="form-group" + {%endif%}> + <label for="select-population-genetic-type" + class="form-label">Genetic Type</label> + <select id="select-population-genetic-type" + name="population_genetic_type" + class="form-control"> + <option value="">Select proper genetic type</option> + {%for gtype in genetic_types%} + <option value="{{gtype}}" + {%if error_values.population_genetic_type == gtype%} + selected="selected" + {%endif%}>{{gtype}}</option> + {%endfor%} + </select> + <small class="form-text text-muted text-danger"> + <p> + <span class="glyphicon glyphicon-exclamation-sign"></span> + This might be a poorly named field. + </p> + <p> + It probably has more to do with the mating crosses/crossings used to + produce the individuals in the population. I am no biologist, however, + and I'm leaving this here to remind myself to confirm this. + </p> + <p> + I still don't know what riset is.<br /> + … probably something to do with Recombinant Inbred Strains + </p> + <p> + Possible resources for this: + <ul> + <li>https://www.informatics.jax.org/silver/chapters/3-2.shtml</li> + <li>https://www.informatics.jax.org/silver/chapters/9-2.shtml</li> + </ul> + </p> + </small> + </div> + + <div class="form-group"> + <input type="submit" + value="create population" + class="btn btn-primary" /> + </div> + + </form> +</div> +{%endblock%} + +{%block sidebarcontents%} +{{display_species_card(species)}} +{%endblock%} diff --git a/uploader/templates/populations/index.html b/uploader/templates/populations/index.html new file mode 100644 index 0000000..d2bee77 --- /dev/null +++ b/uploader/templates/populations/index.html @@ -0,0 +1,28 @@ +{%extends "populations/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "species/macro-select-species.html" import select_species_form%} + +{%block title%}Populations{%endblock%} + +{%block pagetitle%}Populations{%endblock%} + + +{%block contents%} +{{flash_all_messages()}} + +<div class="row"> + <p> + Your experiment data will relate to a particular population from a + particular species. Let us know what species it is you want to work with + below. + </p> +</div> + +<div class="row"> + {{select_species_form(url_for("species.populations.index"), species)}} +</div> +{%endblock%} + +{%block javascript%} +<script type="text/javascript" src="/static/js/species.js"></script> +{%endblock%} diff --git a/uploader/templates/populations/list-populations.html b/uploader/templates/populations/list-populations.html new file mode 100644 index 0000000..f780e94 --- /dev/null +++ b/uploader/templates/populations/list-populations.html @@ -0,0 +1,93 @@ +{%extends "populations/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "species/macro-select-species.html" import select_species_form%} +{%from "species/macro-display-species-card.html" import display_species_card%} + +{%block title%}Populations{%endblock%} + +{%block pagetitle%}Populations{%endblock%} + +{%block lvl3_breadcrumbs%} +<li {%if activelink=="list-populations"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.list_species_populations', + species_id=species.SpeciesId)}}">List populations</a> +</li> +{%endblock%} + + +{%block contents%} +{{flash_all_messages()}} +<div class="row"> + <p> + The following populations/groups exist for the '{{species.FullName}}' + species. + </p> + <p> + Click on the population's name to select and continue using the population. + </p> +</div> + +<div class="row"> + <p> + If the population you need for the species '{{species.FullName}}' does not + exist, click on the "Create Population" button below to create a new one. + </p> + <p> + <a href="{{url_for('species.populations.create_population', + species_id=species.SpeciesId)}}" + title="Create a new population for species '{{species.FullName}}'." + class="btn btn-danger"> + Create Population + </a> + </p> +</div> + +<div class="row"> + <table class="table"> + <caption>Populations for {{species.FullName}}</caption> + <thead> + <tr> + <th></th> + <th>Name</th> + <th>Full Name</th> + <th>Description</th> + </tr> + </thead> + + <tbody> + {%for population in populations%} + <tr> + <td>{{population["sequence_number"]}}</td> + <td> + <a href="{{url_for('species.populations.view_population', + species_id=species.SpeciesId, + population_id=population.InbredSetId)}}" + title="Population '{{population.FullName}}' for species '{{species.FullName}}'."> + {{population.Name}} + </a> + </td> + <td>{{population.FullName}}</td> + <td>{{population.Description}}</td> + </tr> + {%else%} + <tr> + <td colspan="3"> + <p class="text-danger"> + <span class="glyphicon glyphicon-exclamation-mark"></span> + There were no populations found for {{species.FullName}}! + </p> + </td> + </tr> + {%endfor%} + </tbody> + </table> +</div> +{%endblock%} + +{%block sidebarcontents%} +{{display_species_card(species)}} +{%endblock%} diff --git a/uploader/templates/populations/macro-display-population-card.html b/uploader/templates/populations/macro-display-population-card.html new file mode 100644 index 0000000..16b477f --- /dev/null +++ b/uploader/templates/populations/macro-display-population-card.html @@ -0,0 +1,41 @@ +{%from "species/macro-display-species-card.html" import display_species_card%} + +{%macro display_population_card(species, population)%} +{{display_species_card(species)}} + +<div class="card"> + <div class="card-body"> + <h5 class="card-title">Population</h5> + <div class="card-text"> + <table class="table"> + <tbody> + <tr> + <td>Name</td> + <td>{{population.Name}}</td> + </tr> + + <tr> + <td>Full Name</td> + <td>{{population.FullName}}</td> + </tr> + + <tr> + <td>Code</td> + <td>{{population.InbredSetCode}}</td> + </tr> + + <tr> + <td>Genetic Type</td> + <td>{{population.GeneticType}}</td> + </tr> + + <tr> + <td>Family</td> + <td>{{population.Family}}</td> + </tr> + </tbody> + </table> + </div> + </div> +</div> +{%endmacro%} diff --git a/uploader/templates/populations/macro-select-population.html b/uploader/templates/populations/macro-select-population.html new file mode 100644 index 0000000..14b0510 --- /dev/null +++ b/uploader/templates/populations/macro-select-population.html @@ -0,0 +1,52 @@ +{%from "macro-step-indicator.html" import step_indicator%} + +{%macro select_population_form(form_action, species, populations)%} +<form method="GET" action="{{form_action}}" class="form-horizontal"> + + <h2>{{step_indicator("2")}} What population do you want to work with?</h2> + + {%if populations | length != 0%} + + <p class="form-text">Search for, and select the population from the table + below and click "Continue"</p> + + <div class="radio"> + <label class="control-label" for="rdo-cant-find-population"> + <input type="radio" id="rdo-cant-find-population" + name="population_id" value="CREATE-POPULATION" /> + I cannot find the population I want — create it! + </label> + </div> + + <div class="col-sm-offset-10 col-sm-2"> + <input type="submit" value="continue" class="btn btn-primary" /> + </div> + + <div style="margin-top:3em;"> + <table id="tbl-select-population" class="table compact stripe" + data-populations-list='{{populations | tojson}}'> + <thead> + <tr> + <th></th> + <th>Population</th> + </tr> + </thead> + + <tbody></tbody> + </table> + </div> + + {%else%} + <p class="form-text"> + There are no populations currently defined for {{species['FullName']}} + ({{species['SpeciesName']}}).<br /> + Click "Continue" to create the first!</p> + <input type="hidden" name="population_id" value="CREATE-POPULATION" /> + + <div class="col-sm-offset-10 col-sm-2"> + <input type="submit" value="continue" class="btn btn-primary" /> + </div> + {%endif%} + +</form> +{%endmacro%} diff --git a/uploader/templates/rqtl2/create-tissue-success.html b/uploader/templates/populations/rqtl2/create-tissue-success.html index 5f2c5a0..d6fe154 100644 --- a/uploader/templates/rqtl2/create-tissue-success.html +++ b/uploader/templates/populations/rqtl2/create-tissue-success.html @@ -56,7 +56,7 @@ <form id="frm-create-tissue-success-continue" method="POST" - action="{{url_for('upload.rqtl2.select_dataset_info', + action="{{url_for('expression-data.rqtl2.select_dataset_info', species_id=species.SpeciesId, population_id=population.InbredSetId)}}" style="display: inline; width: 100%; grid-column: 1 / 2; @@ -85,7 +85,7 @@ <div class="row"> <form id="frm-create-tissue-success-select-existing" method="POST" - action="{{url_for('upload.rqtl2.select_tissue', + action="{{url_for('expression-data.rqtl2.select_tissue', species_id=species.SpeciesId, population_id=population.InbredSetId)}}" style="display: inline; width: 100%; grid-column: 3 / 4; diff --git a/uploader/templates/populations/rqtl2/index.html b/uploader/templates/populations/rqtl2/index.html new file mode 100644 index 0000000..ec6ffb8 --- /dev/null +++ b/uploader/templates/populations/rqtl2/index.html @@ -0,0 +1,54 @@ +{%extends "base.html"%} +{%from "flash_messages.html" import flash_messages%} + +{%block title%}Data Upload{%endblock%} + +{%block contents%} +<h1 class="heading">R/qtl2 data upload</h1> + +<h2>R/qtl2 Upload</h2> + +<div class="row"> + <form method="POST" action="{{url_for('expression-data.rqtl2.select_species')}}" + id="frm-rqtl2-upload"> + <legend class="heading">upload R/qtl2 bundle</legend> + {{flash_messages("error-rqtl2")}} + + <div class="form-group"> + <label for="select:species" class="form-label">Species</label> + <select id="select:species" + name="species_id" + required="required" + class="form-control"> + <option value="">Select species</option> + {%for spec in species%} + <option value="{{spec.SpeciesId}}">{{spec.MenuName}}</option> + {%endfor%} + </select> + <small class="form-text text-muted"> + Data that you upload to the system should belong to a know species. + Here you can select the species that you wish to upload data for. + </small> + </div> + + <input type="submit" class="btn btn-primary" value="submit" /> + </form> +</div> + +<div class="row"> + <h2 class="heading">R/qtl2 Bundles</h2> + + <div class="explainer"> + <p>This feature combines and extends the two upload methods below. Instead of + uploading one item at a time, the R/qtl2 bundle you upload can contain both + the genotypes data (samples/individuals/cases and their data) and the + expression data.</p> + <p>The R/qtl2 bundle, additionally, can contain extra metadata, that neither + of the methods below can handle.</p> + + <a href="{{url_for('expression-data.rqtl2.select_species')}}" + title="Upload a zip bundle of R/qtl2 files"> + <button class="btn btn-primary">upload R/qtl2 bundle</button></a> + </div> +</div> +{%endblock%} diff --git a/uploader/templates/rqtl2/no-such-job.html b/uploader/templates/populations/rqtl2/no-such-job.html index b17004f..b17004f 100644 --- a/uploader/templates/rqtl2/no-such-job.html +++ b/uploader/templates/populations/rqtl2/no-such-job.html diff --git a/uploader/templates/rqtl2/rqtl2-job-error.html b/uploader/templates/populations/rqtl2/rqtl2-job-error.html index 9817518..9817518 100644 --- a/uploader/templates/rqtl2/rqtl2-job-error.html +++ b/uploader/templates/populations/rqtl2/rqtl2-job-error.html diff --git a/uploader/templates/rqtl2/rqtl2-job-results.html b/uploader/templates/populations/rqtl2/rqtl2-job-results.html index 4ecd415..4ecd415 100644 --- a/uploader/templates/rqtl2/rqtl2-job-results.html +++ b/uploader/templates/populations/rqtl2/rqtl2-job-results.html diff --git a/uploader/templates/rqtl2/rqtl2-job-status.html b/uploader/templates/populations/rqtl2/rqtl2-job-status.html index e896f88..e896f88 100644 --- a/uploader/templates/rqtl2/rqtl2-job-status.html +++ b/uploader/templates/populations/rqtl2/rqtl2-job-status.html diff --git a/uploader/templates/rqtl2/rqtl2-qc-job-error.html b/uploader/templates/populations/rqtl2/rqtl2-qc-job-error.html index 90e8887..90e8887 100644 --- a/uploader/templates/rqtl2/rqtl2-qc-job-error.html +++ b/uploader/templates/populations/rqtl2/rqtl2-qc-job-error.html diff --git a/uploader/templates/rqtl2/rqtl2-qc-job-results.html b/uploader/templates/populations/rqtl2/rqtl2-qc-job-results.html index 59bc8cd..b3c3a8f 100644 --- a/uploader/templates/rqtl2/rqtl2-qc-job-results.html +++ b/uploader/templates/populations/rqtl2/rqtl2-qc-job-results.html @@ -15,7 +15,7 @@ <div class="row"> <form id="form-qc-job-results" - action="{{url_for('upload.rqtl2.select_dataset_info', + action="{{url_for('expression-data.rqtl2.select_dataset_info', species_id=species.SpeciesId, population_id=population.Id)}}" method="POST"> diff --git a/uploader/templates/rqtl2/rqtl2-qc-job-status.html b/uploader/templates/populations/rqtl2/rqtl2-qc-job-status.html index f4a6266..f4a6266 100644 --- a/uploader/templates/rqtl2/rqtl2-qc-job-status.html +++ b/uploader/templates/populations/rqtl2/rqtl2-qc-job-status.html diff --git a/uploader/templates/rqtl2/rqtl2-qc-job-success.html b/uploader/templates/populations/rqtl2/rqtl2-qc-job-success.html index 2861a04..f126835 100644 --- a/uploader/templates/rqtl2/rqtl2-qc-job-success.html +++ b/uploader/templates/populations/rqtl2/rqtl2-qc-job-success.html @@ -18,7 +18,7 @@ --> <div class="row"> <form id="frm-upload-rqtl2-bundle" - action="{{url_for('upload.rqtl2.select_dataset_info', + action="{{url_for('expression-data.rqtl2.select_dataset_info', species_id=species.SpeciesId, population_id=population.InbredSetId)}}" method="POST" diff --git a/uploader/templates/populations/rqtl2/select-geno-dataset.html b/uploader/templates/populations/rqtl2/select-geno-dataset.html new file mode 100644 index 0000000..3233abc --- /dev/null +++ b/uploader/templates/populations/rqtl2/select-geno-dataset.html @@ -0,0 +1,69 @@ +{%extends "base.html"%} +{%from "flash_messages.html" import flash_messages%} + +{%block title%}Upload R/qtl2 Bundle{%endblock%} + +{%block contents%} +<h2 class="heading">Select Genotypes Dataset</h2> + +<div class="row"> + <p>Your R/qtl2 files bundle could contain a "geno" specification. You will + therefore need to select from one of the existing Genotype datasets or + create a new one.</p> + <p>This is the dataset where your data will be organised under.</p> +</div> + +<div class="row"> + <form id="frm-upload-rqtl2-bundle" + action="{{url_for('expression-data.rqtl2.select_geno_dataset', + species_id=species.SpeciesId, + population_id=population.InbredSetId)}}" + method="POST" + enctype="multipart/form-data"> + <legend class="heading">select from existing genotype datasets</legend> + + <input type="hidden" name="species_id" value="{{species.SpeciesId}}" /> + <input type="hidden" name="population_id" + value="{{population.InbredSetId}}" /> + <input type="hidden" name="rqtl2_bundle_file" + value="{{rqtl2_bundle_file}}" /> + + {{flash_messages("error-rqtl2-select-geno-dataset")}} + + <div class="form-group"> + <legend>Datasets</legend> + <label for="select:geno-datasets" class="form-label">Dataset</label> + <select id="select:geno-datasets" + name="geno-dataset-id" + required="required" + {%if datasets | length == 0%} + disabled="disabled" + {%endif%} + class="form-control" + aria-describedby="help-geno-dataset-select-dataset"> + <option value="">Select dataset</option> + {%for dset in datasets%} + <option value="{{dset['Id']}}">{{dset["Name"]}} ({{dset["FullName"]}})</option> + {%endfor%} + </select> + <span id="help-geno-dataset-select-dataset" class="form-text text-muted"> + Select from the existing genotype datasets for species + {{species.SpeciesName}} ({{species.FullName}}). + </span> + </div> + + <button type="submit" class="btn btn-primary">select dataset</button> + </form> +</div> + +<div class="row"> + <p>If the genotype dataset you need does not currently exist for your dataset, + go the <a href="{{url_for( + 'species.populations.genotypes.create_dataset', + species_id=species.SpeciesId, + population_id=population.Id)}}" + title="Create a new genotypes dataset for {{species.FullName}}"> + genotypes page to create the genotype dataset</a></p> +</div> + +{%endblock%} diff --git a/uploader/templates/populations/rqtl2/select-population.html b/uploader/templates/populations/rqtl2/select-population.html new file mode 100644 index 0000000..ded425f --- /dev/null +++ b/uploader/templates/populations/rqtl2/select-population.html @@ -0,0 +1,57 @@ +{%extends "expression-data/index.html"%} +{%from "flash_messages.html" import flash_messages%} +{%from "species/macro-display-species-card.html" import display_species_card%} + +{%block title%}Select Grouping/Population{%endblock%} + +{%block contents%} +<h1 class="heading">Select grouping/population</h1> + +<div class="row"> + <p>The data is organised in a hierarchical form, beginning with + <em>species</em> at the very top. Under <em>species</em> the data is + organised by <em>population</em>, sometimes referred to as <em>grouping</em>. + (In some really old documents/systems, you might see this referred to as + <em>InbredSet</em>.)</p> + <p>In this section, you get to define what population your data is to be + organised by.</p> +</div> + +<div class="row"> + <form method="POST" + action="{{url_for('expression-data.rqtl2.select_population', + species_id=species.SpeciesId)}}"> + <legend class="heading">select grouping/population</legend> + {{flash_messages("error-select-population")}} + + <input type="hidden" name="species_id" value="{{species.SpeciesId}}" /> + + <div class="form-group"> + <label for="select:inbredset" class="form-label">population</label> + <select id="select:inbredset" + name="inbredset_id" + required="required" + class="form-control"> + <option value="">Select a grouping/population</option> + {%for pop in populations%} + <option value="{{pop.InbredSetId}}"> + {{pop.InbredSetName}} ({{pop.FullName}})</option> + {%endfor%} + </select> + <span class="form-text text-muted">Select the population for your data from + the list below.</span> + </div> + + <button type="submit" class="btn btn-primary" />select population</button> +</form> +</div> + +{%endblock%} + +{%block sidebarcontents%} +{{display_species_card(species)}} +{%endblock%} + + +{%block javascript%} +{%endblock%} diff --git a/uploader/templates/rqtl2/select-probeset-dataset.html b/uploader/templates/populations/rqtl2/select-probeset-dataset.html index 26f52ed..74f8f69 100644 --- a/uploader/templates/rqtl2/select-probeset-dataset.html +++ b/uploader/templates/populations/rqtl2/select-probeset-dataset.html @@ -15,7 +15,7 @@ {%if datasets | length > 0%} <div class="row"> <form method="POST" - action="{{url_for('upload.rqtl2.select_probeset_dataset', + action="{{url_for('expression-data.rqtl2.select_probeset_dataset', species_id=species.SpeciesId, population_id=population.Id)}}" id="frm:select-probeset-dataset"> <legend class="heading">Select from existing ProbeSet datasets</legend> @@ -68,7 +68,7 @@ <div class="row"> <form method="POST" - action="{{url_for('upload.rqtl2.create_probeset_dataset', + action="{{url_for('expression-data.rqtl2.create_probeset_dataset', species_id=species.SpeciesId, population_id=population.Id)}}" id="frm:create-probeset-dataset"> <legend class="heading">Create a new ProbeSet dataset</legend> diff --git a/uploader/templates/rqtl2/select-probeset-study-id.html b/uploader/templates/populations/rqtl2/select-probeset-study-id.html index b9bf52e..e3fd9cc 100644 --- a/uploader/templates/rqtl2/select-probeset-study-id.html +++ b/uploader/templates/populations/rqtl2/select-probeset-study-id.html @@ -12,7 +12,7 @@ <p>In this page, you can either select from a existing dataset:</p> <form method="POST" - action="{{url_for('upload.rqtl2.select_probeset_study', + action="{{url_for('expression-data.rqtl2.select_probeset_study', species_id=species.SpeciesId, population_id=population.Id)}}" id="frm:select-probeset-study"> <legend class="heading">Select from existing ProbeSet studies</legend> @@ -62,7 +62,7 @@ <p>Create a new ProbeSet dataset below:</p> <form method="POST" - action="{{url_for('upload.rqtl2.create_probeset_study', + action="{{url_for('expression-data.rqtl2.create_probeset_study', species_id=species.SpeciesId, population_id=population.Id)}}" id="frm:create-probeset-study"> <legend class="heading">Create new ProbeSet study</legend> diff --git a/uploader/templates/rqtl2/select-tissue.html b/uploader/templates/populations/rqtl2/select-tissue.html index 34e1758..fe3080a 100644 --- a/uploader/templates/rqtl2/select-tissue.html +++ b/uploader/templates/populations/rqtl2/select-tissue.html @@ -15,7 +15,7 @@ {%if tissues | length > 0%} <div class="row"> <form method="POST" - action="{{url_for('upload.rqtl2.select_tissue', + action="{{url_for('expression-data.rqtl2.select_tissue', species_id=species.SpeciesId, population_id=population.Id)}}" id="frm:select-probeset-dataset"> <legend class="heading">Select from existing ProbeSet datasets</legend> @@ -65,7 +65,7 @@ to the system below.</p> <form method="POST" - action="{{url_for('upload.rqtl2.create_tissue', + action="{{url_for('expression-data.rqtl2.create_tissue', species_id=species.SpeciesId, population_id=population.Id)}}" id="frm:create-probeset-dataset"> <legend class="heading">Add new tissue, organ or biological material</legend> diff --git a/uploader/templates/rqtl2/summary-info.html b/uploader/templates/populations/rqtl2/summary-info.html index 1be87fa..0adba2e 100644 --- a/uploader/templates/rqtl2/summary-info.html +++ b/uploader/templates/populations/rqtl2/summary-info.html @@ -44,7 +44,7 @@ <div class="row"> <form id="frm:confirm-rqtl2bundle-details" - action="{{url_for('upload.rqtl2.confirm_bundle_details', + action="{{url_for('expression-data.rqtl2.confirm_bundle_details', species_id=species.SpeciesId, population_id=population.InbredSetId)}}" method="POST" diff --git a/uploader/templates/rqtl2/upload-rqtl2-bundle-step-01.html b/uploader/templates/populations/rqtl2/upload-rqtl2-bundle-step-01.html index 07c240f..9d45c5f 100644 --- a/uploader/templates/rqtl2/upload-rqtl2-bundle-step-01.html +++ b/uploader/templates/populations/rqtl2/upload-rqtl2-bundle-step-01.html @@ -71,13 +71,13 @@ </div> <form id="frm-upload-rqtl2-bundle" - action="{{url_for('upload.rqtl2.upload_rqtl2_bundle', + action="{{url_for('expression-data.rqtl2.upload_rqtl2_bundle', species_id=species.SpeciesId, population_id=population.InbredSetId)}}" method="POST" enctype="multipart/form-data" data-resumable-target="{{url_for( - 'upload.rqtl2.upload_rqtl2_bundle_chunked_post', + 'expression-data.rqtl2.upload_rqtl2_bundle_chunked_post', species_id=species.SpeciesId, population_id=population.InbredSetId)}}"> <input type="hidden" name="species_id" value="{{species.SpeciesId}}" /> diff --git a/uploader/templates/rqtl2/upload-rqtl2-bundle-step-02.html b/uploader/templates/populations/rqtl2/upload-rqtl2-bundle-step-02.html index 93b1dc9..8210ed0 100644 --- a/uploader/templates/rqtl2/upload-rqtl2-bundle-step-02.html +++ b/uploader/templates/populations/rqtl2/upload-rqtl2-bundle-step-02.html @@ -14,7 +14,7 @@ <p>Click "Continue" below to proceed.</p> <form id="frm-upload-rqtl2-bundle" - action="{{url_for('upload.rqtl2.select_dataset_info', + action="{{url_for('expression-data.rqtl2.select_dataset_info', species_id=species.SpeciesId, population_id=population.InbredSetId)}}" method="POST" diff --git a/uploader/templates/populations/view-population.html b/uploader/templates/populations/view-population.html new file mode 100644 index 0000000..b23caeb --- /dev/null +++ b/uploader/templates/populations/view-population.html @@ -0,0 +1,102 @@ +{%extends "populations/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "species/macro-select-species.html" import select_species_form%} +{%from "species/macro-display-species-card.html" import display_species_card%} + +{%block title%}Populations{%endblock%} + +{%block pagetitle%}Populations{%endblock%} + +{%block lvl3_breadcrumbs%} +<li {%if activelink=="view-population"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.view_population', + species_id=species.SpeciesId, + population_id=population.InbredSetId)}}">view</a> +</li> +{%endblock%} + + +{%block contents%} +<div class="row"> + <h2>Population Details</h2> + + {{flash_all_messages()}} + + <dl> + <dt>Name</dt> + <dd>{{population.Name}}</dd> + + <dt>FullName</dt> + <dd>{{population.FullName}}</dd> + + <dt>Code</dt> + <dd>{{population.InbredSetCode}}</dd> + + <dt>Genetic Type</dt> + <dd>{{population.GeneticType}}</dd> + + <dt>Family</dt> + <dd>{{population.Family}}</dd> + + <dt>Description</dt> + <dd><pre>{{population.Description or "-"}}</pre></dd> + </dl> +</div> + +<div class="row"> + … maybe provide a way to organise populations in the same family here … +</div> + +<div class="row"> + <h3>Actions</h3> + + <p> + Click any of the following links to use this population in performing the + subsequent operations. + </p> + + <nav class="nav"> + <ul> + <li> + <a href="{{url_for('species.populations.samples.list_samples', + species_id=species.SpeciesId, + population_id=population.Id)}}" + title="Manage samples: Add new or delete existing."> + manage samples</a> + </li> + <li> + <a href="{{url_for('species.populations.genotypes.list_genotypes', + species_id=species.SpeciesId, + population_id=population.Id)}}" + title="Manage genotypes for {{species.FullName}}">Manage Genotypes</a> + </li> + <li> + <a href="{{url_for('species.populations.phenotypes.list_datasets', + species_id=species.SpeciesId, + population_id=population.Id)}}" + title="Manage phenotype data.">manage phenotype data</a> + </li> + <li> + <a href="#" title="Manage expression data" + class="not-implemented">manage expression data</a> + </li> + <li> + <a href="#" title="Manage individual data" + class="not-implemented">manage individual data</a> + </li> + <li> + <a href="#" title="Manage RNA-Seq data" + class="not-implemented">manage RNA-Seq data</a> + </li> + </ul> + </nav> +</div> +{%endblock%} + +{%block sidebarcontents%} +{{display_species_card(species)}} +{%endblock%} diff --git a/uploader/templates/publications/base.html b/uploader/templates/publications/base.html new file mode 100644 index 0000000..db80bfa --- /dev/null +++ b/uploader/templates/publications/base.html @@ -0,0 +1,12 @@ +{%extends "base.html"%} + +{%block lvl1_breadcrumbs%} +<li {%if activelink=="publications"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('publications.index')}}">Publications</a> +</li> +{%block lvl2_breadcrumbs%}{%endblock%} +{%endblock%} diff --git a/uploader/templates/publications/create-publication.html b/uploader/templates/publications/create-publication.html new file mode 100644 index 0000000..3f828a9 --- /dev/null +++ b/uploader/templates/publications/create-publication.html @@ -0,0 +1,191 @@ +{%extends "publications/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} + +{%block title%}View Publication{%endblock%} + +{%block pagetitle%}View Publication{%endblock%} + + +{%block contents%} +{{flash_all_messages()}} + +<div class="row"> + <form id="frm-create-publication" + method="POST" + action="{{url_for('publications.create_publication', **request.args)}}" + class="form-horizontal"> + + <div class="row mb-3"> + <label for="txt-pubmed-id" class="col-sm-2 col-form-label"> + PubMed ID</label> + <div class="col-sm-10"> + <div class="input-group"> + <input type="text" + id="txt-pubmed-id" + name="pubmed-id" + class="form-control"/> + <div class="input-group-text"> + <button class="btn btn-outline-primary" + id="btn-search-pubmed-id">search</button> + </div> + </div> + <span id="search-pubmed-id-error" + class="form-text text-muted text-danger visually-hidden"> + </span> + <span class="form-text text-muted">This is the publication's ID on + <a href="https://pubmed.ncbi.nlm.nih.gov/" + title="Link to NCBI's PubMed service">NCBI's Pubmed Service</a> + </span> + </div> + </div> + + <div class="row mb-3"> + <label for="txt-publication-title" class="col-sm-2 col-form-label"> + Title</label> + <div class="col-sm-10"> + <input type="text" + id="txt-publication-title" + name="publication-title" + class="form-control" /> + <span class="form-text text-muted">Provide the publication's title here.</span> + </div> + </div> + + <div class="row mb-3"> + <label for="txt-publication-authors" class="col-sm-2 col-form-label"> + Authors</label> + <div class="col-sm-10"> + <input type="text" + id="txt-publication-authors" + name="publication-authors" + required="required" + class="form-control" /> + <span class="form-text text-muted"> + A publication <strong>MUST</strong> have an author. You <em>must</em> + provide a value for the authors field. + </span> + </div> + </div> + + <div class="row mb-3"> + <label for="txt-publication-journal" class="col-sm-2 col-form-label"> + Journal</label> + <div class="col-sm-10"> + <input type="text" + id="txt-publication-journal" + name="publication-journal" + class="form-control" /> + <span class="form-text text-muted">Provide the name journal where the + publication was done, here.</span> + </div> + </div> + + <div class="row mb-3"> + <label for="select-publication-month" + class="col-sm-2 col-form-label"> + Month</label> + <div class="col-sm-4"> + <select class="form-control" + id="select-publication-month" + name="publication-month"> + <option value="">Select a month</option> + <option value="january">January</option> + <option value="february">February</option> + <option value="march">March</option> + <option value="april">April</option> + <option value="may">May</option> + <option value="june">June</option> + <option value="july">July</option> + <option value="august">August</option> + <option value="september">September</option> + <option value="october">October</option> + <option value="november">November</option> + <option value="december">December</option> + </select> + <span class="form-text text-muted">Month of publication</span> + </div> + + <label for="txt-publication-year" + class="col-sm-2 col-form-label"> + Year</label> + <div class="col-sm-4"> + <input type="number" + id="txt-publication-year" + name="publication-year" + class="form-control" + min="1960" /> + <span class="form-text text-muted">Year of publication</span> + </div> + </div> + + <div class="row mb-3"> + <label for="txt-publication-volume" + class="col-sm-2 col-form-label"> + Volume</label> + <div class="col-sm-4"> + <input type="text" + id="txt-publication-volume" + name="publication-volume" + class="form-control"> + <span class="form-text text-muted">Journal volume</span> + </div> + + <label for="txt-publication-pages" + class="col-sm-2 col-form-label"> + Pages</label> + <div class="col-sm-4"> + <input type="text" + id="txt-publication-pages" + name="publication-pages" + class="form-control" /> + <span class="form-text text-muted">Journal pages for the publication</span> + </div> + </div> + + <div class="row mb-3"> + <label for="txt-abstract" class="col-sm-2 col-form-label">Abstract</label> + <div class="col-sm-10"> + <textarea id="txt-publication-abstract" + name="publication-abstract" + class="form-control" + rows="7"></textarea> + </div> + </div> + + <div class="row mb-3"> + <div class="col-sm-2"></div> + <div class="col-sm-8"> + <input type="submit" class="btn btn-primary" value="Add" /> + <input type="reset" class="btn btn-danger" /> + </div> + </div> + +</form> +</div> + +{%endblock%} + + +{%block javascript%} +<script type="text/javascript" src="/static/js/pubmed.js"></script> +<script type="text/javascript"> + $(function() { + $("#btn-search-pubmed-id").on("click", (event) => { + event.preventDefault(); + var search_button = event.target; + var pubmed_id = $("#txt-pubmed-id").val().trim(); + remove_class($("#txt-pubmed-id").parent(), "has-error"); + if(pubmed_id == "") { + add_class($("#txt-pubmed-id").parent(), "has-error"); + return false; + } + + search_button.disabled = true; + // Fetch publication details + fetch_publication_details(pubmed_id, + [() => {search_button.disabled = false;}]); + return false; + }); + }); +</script> +{%endblock%} diff --git a/uploader/templates/publications/index.html b/uploader/templates/publications/index.html new file mode 100644 index 0000000..f846d54 --- /dev/null +++ b/uploader/templates/publications/index.html @@ -0,0 +1,92 @@ +{%extends "publications/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} + +{%block title%}Publications{%endblock%} + +{%block pagetitle%}Publications{%endblock%} + + +{%block contents%} +{{flash_all_messages()}} + +<div class="row" style="padding-bottom: 1em;"> + <a href="{{url_for('publications.create_publication')}}" + class="btn btn-primary"> + add new publication</a> +</div> + +<div class="row"> + <table id="tbl-list-publications" class="table compact stripe"> + <thead> + <tr> + <th>#</th> + <th>PubMed ID</th> + <th>Title</th> + <th>Authors</th> + </tr> + </thead> + + <tbody></tbody> + </table> +</div> +{%endblock%} + + +{%block javascript%} +<script type="text/javascript"> + $(function() { + var publicationsDataTable = buildDataTable( + "#tbl-list-publications", + [], + [ + {data: "index"}, + { + data: (pub) => { + if(pub.PubMed_ID) { + return `<a href="https://pubmed.ncbi.nlm.nih.gov/` + + `${pub.PubMed_ID}/" target="_blank" ` + + `title="Link to publication on NCBI.">` + + `${pub.PubMed_ID}</a>`; + } + return ""; + } + }, + { + data: (pub) => { + var title = "⸻"; + if(pub.Title) { + title = pub.Title + } + return `<a href="/publications/view/${pub.Id}" ` + + `target="_blank" ` + + `title="Link to view publication details">` + + `${title}</a>`; + } + }, + { + data: (pub) => { + authors = pub.Authors.split(",").map( + (item) => {return item.trim();}); + if(authors.length > 1) { + return authors[0] + ", et. al."; + } + return authors[0]; + } + } + ], + { + ajax: { + url: "/publications/list", + dataSrc: "publications" + }, + scrollY: 700, + paging: false, + deferRender: true, + layout: { + topStart: "info", + topEnd: "search" + } + }); + }); +</script> +{%endblock%} diff --git a/uploader/templates/publications/view-publication.html b/uploader/templates/publications/view-publication.html new file mode 100644 index 0000000..388547a --- /dev/null +++ b/uploader/templates/publications/view-publication.html @@ -0,0 +1,78 @@ +{%extends "publications/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} + +{%block title%}View Publication{%endblock%} + +{%block pagetitle%}View Publication{%endblock%} + + +{%block contents%} +{{flash_all_messages()}} + +<div class="row"> + <table class="table"> + <tr> + <th>PubMed</th> + <td> + {%if publication.PubMed_ID%} + <a href="https://pubmed.ncbi.nlm.nih.gov/{{publication.PubMed_ID}}/" + target="_blank">{{publication.PubMed_ID}}</a> + {%else%} + — + {%endif%} + </td> + </tr> + <tr> + <th>Title</th> + <td>{{publication.Title or "—"}}</td> + </tr> + <tr> + <th>Authors</th> + <td>{{publication.Authors or "—"}}</td> + </tr> + <tr> + <th>Journal</th> + <td>{{publication.Journal or "—"}}</td> + </tr> + <tr> + <th>Published</th> + <td>{{publication.Month or ""}} {{publication.Year or "—"}}</td> + </tr> + <tr> + <th>Volume</th> + <td>{{publication.Volume or "—"}}</td> + </tr> + <tr> + <th>Pages</th> + <td>{{publication.Pages or "—"}}</td> + </tr> + <tr> + <th>Abstract</th> + <td> + {%for line in (publication.Abstract or "—").replace("\r\n", "<br />").replace("\n", "<br />").split("<br />")%} + <p>{{line}}</p> + {%endfor%} + </td> + </tr> + </table> +</div> + +<div class="row"> + <form id="frm-edit-delete-publication" method="POST" action="#"> + <input type="hidden" name="publication_id" value="{{publication.Id}}" /> + <div class="form-group"> + <input type="submit" value="edit" class="btn btn-primary not-implemented" /> + {%if linked_phenotypes | length == 0%} + <input type="submit" value="delete" class="btn btn-danger not-implemented" /> + {%endif%} + </div> + </form> +</div> +{%endblock%} + + +{%block javascript%} +<script type="text/javascript"> + $(function() {}); +</script> +{%endblock%} diff --git a/uploader/templates/rqtl2/create-geno-dataset-success.html b/uploader/templates/rqtl2/create-geno-dataset-success.html deleted file mode 100644 index 1b50221..0000000 --- a/uploader/templates/rqtl2/create-geno-dataset-success.html +++ /dev/null @@ -1,55 +0,0 @@ -{%extends "base.html"%} -{%from "flash_messages.html" import flash_messages%} - -{%block title%}Upload R/qtl2 Bundle{%endblock%} - -{%block contents%} -<h2 class="heading">Select Genotypes Dataset</h2> - -<div class="explainer"> - <p>You successfully created the genotype dataset with the following - information. - <dl> - <dt>ID</dt> - <dd>{{geno_dataset.id}}</dd> - - <dt>Name</dt> - <dd>{{geno_dataset.name}}</dd> - - <dt>Full Name</dt> - <dd>{{geno_dataset.fname}}</dd> - - <dt>Short Name</dt> - <dd>{{geno_dataset.sname}}</dd> - - <dt>Created On</dt> - <dd>{{geno_dataset.today}}</dd> - - <dt>Public?</dt> - <dd>{%if geno_dataset.public == 0%}No{%else%}Yes{%endif%}</dd> - </dl> - </p> -</div> - -<div class="row"> - <form id="frm-upload-rqtl2-bundle" - action="{{url_for('upload.rqtl2.select_dataset_info', - species_id=species.SpeciesId, - population_id=population.InbredSetId)}}" - method="POST" - enctype="multipart/form-data"> - <legend class="heading">select from existing genotype datasets</legend> - - <input type="hidden" name="species_id" value="{{species.SpeciesId}}" /> - <input type="hidden" name="population_id" - value="{{population.InbredSetId}}" /> - <input type="hidden" name="rqtl2_bundle_file" - value="{{rqtl2_bundle_file}}" /> - <input type="hidden" name="geno-dataset-id" - value="{{geno_dataset.id}}" /> - - <button type="submit" class="btn btn-primary">continue</button> - </form> -</div> - -{%endblock%} diff --git a/uploader/templates/rqtl2/create-probe-dataset-success.html b/uploader/templates/rqtl2/create-probe-dataset-success.html deleted file mode 100644 index 790d174..0000000 --- a/uploader/templates/rqtl2/create-probe-dataset-success.html +++ /dev/null @@ -1,59 +0,0 @@ -{%extends "base.html"%} -{%from "flash_messages.html" import flash_messages%} - -{%block title%}Upload R/qtl2 Bundle{%endblock%} - -{%block contents%} -<h2 class="heading">Create ProbeSet Dataset</h2> - -<div class="row"> - <p>You successfully created the ProbeSet dataset with the following - information. - <dl> - <dt>Averaging Method</dt> - <dd>{{avgmethod.Name}}</dd> - - <dt>ID</dt> - <dd>{{dataset.datasetid}}</dd> - - <dt>Name</dt> - <dd>{{dataset.name2}}</dd> - - <dt>Full Name</dt> - <dd>{{dataset.fname}}</dd> - - <dt>Short Name</dt> - <dd>{{dataset.sname}}</dd> - - <dt>Created On</dt> - <dd>{{dataset.today}}</dd> - - <dt>DataScale</dt> - <dd>{{dataset.datascale}}</dd> - </dl> - </p> -</div> - -<div class="row"> - <form id="frm-upload-rqtl2-bundle" - action="{{url_for('upload.rqtl2.select_dataset_info', - species_id=species.SpeciesId, - population_id=population.InbredSetId)}}" - method="POST" - enctype="multipart/form-data"> - <legend class="heading">Create ProbeSet dataset</legend> - - <input type="hidden" name="species_id" value="{{species.SpeciesId}}" /> - <input type="hidden" name="population_id" - value="{{population.InbredSetId}}" /> - <input type="hidden" name="rqtl2_bundle_file" value="{{rqtl2_bundle_file}}" /> - <input type="hidden" name="geno-dataset-id" value="{{geno_dataset.Id}}" /> - <input type="hidden" name="tissueid" value="{{tissue.Id}}" /> - <input type="hidden" name="probe-study-id" value="{{study.Id}}" /> - <input type="hidden" name="probe-dataset-id" value="{{dataset.datasetid}}" /> - - <button type="submit" class="btn btn-primary">continue</button> - </form> -</div> - -{%endblock%} diff --git a/uploader/templates/rqtl2/create-probe-study-success.html b/uploader/templates/rqtl2/create-probe-study-success.html deleted file mode 100644 index d0ee508..0000000 --- a/uploader/templates/rqtl2/create-probe-study-success.html +++ /dev/null @@ -1,49 +0,0 @@ -{%extends "base.html"%} -{%from "flash_messages.html" import flash_messages%} - -{%block title%}Upload R/qtl2 Bundle{%endblock%} - -{%block contents%} -<h2 class="heading">Create ProbeSet Study</h2> - -<div class="row"> - <p>You successfully created the ProbeSet study with the following - information. - <dl> - <dt>ID</dt> - <dd>{{study.id}}</dd> - - <dt>Name</dt> - <dd>{{study.name}}</dd> - - <dt>Full Name</dt> - <dd>{{study.fname}}</dd> - - <dt>Short Name</dt> - <dd>{{study.sname}}</dd> - - <dt>Created On</dt> - <dd>{{study.today}}</dd> - </dl> - </p> - - <form id="frm-upload-rqtl2-bundle" - action="{{url_for('upload.rqtl2.select_dataset_info', - species_id=species.SpeciesId, - population_id=population.InbredSetId)}}" - method="POST" - enctype="multipart/form-data"> - <legend class="heading">Create ProbeSet study</legend> - - <input type="hidden" name="species_id" value="{{species.SpeciesId}}" /> - <input type="hidden" name="population_id" - value="{{population.InbredSetId}}" /> - <input type="hidden" name="rqtl2_bundle_file" value="{{rqtl2_bundle_file}}" /> - <input type="hidden" name="geno-dataset-id" value="{{geno_dataset.Id}}" /> - <input type="hidden" name="probe-study-id" value="{{study.studyid}}" /> - - <button type="submit" class="btn btn-primary">continue</button> - </form> -</div> - -{%endblock%} diff --git a/uploader/templates/rqtl2/index.html b/uploader/templates/rqtl2/index.html deleted file mode 100644 index f3329c2..0000000 --- a/uploader/templates/rqtl2/index.html +++ /dev/null @@ -1,36 +0,0 @@ -{%extends "base.html"%} -{%from "flash_messages.html" import flash_messages%} - -{%block title%}Data Upload{%endblock%} - -{%block contents%} -<h1 class="heading">R/qtl2 data upload</h1> - -<h2>R/qtl2 Upload</h2> - -<form method="POST" action="{{url_for('upload.rqtl2.select_species')}}" - id="frm-rqtl2-upload"> - <legend class="heading">upload R/qtl2 bundle</legend> - {{flash_messages("error-rqtl2")}} - - <div class="form-group"> - <label for="select:species" class="form-label">Species</label> - <select id="select:species" - name="species_id" - required="required" - class="form-control"> - <option value="">Select species</option> - {%for spec in species%} - <option value="{{spec.SpeciesId}}">{{spec.MenuName}}</option> - {%endfor%} - </select> - <small class="form-text text-muted"> - Data that you upload to the system should belong to a know species. - Here you can select the species that you wish to upload data for. - </small> - </div> - - <button type="submit" class="btn btn-primary" />submit</button> -</form> - -{%endblock%} diff --git a/uploader/templates/rqtl2/select-geno-dataset.html b/uploader/templates/rqtl2/select-geno-dataset.html deleted file mode 100644 index 873f9c3..0000000 --- a/uploader/templates/rqtl2/select-geno-dataset.html +++ /dev/null @@ -1,144 +0,0 @@ -{%extends "base.html"%} -{%from "flash_messages.html" import flash_messages%} - -{%block title%}Upload R/qtl2 Bundle{%endblock%} - -{%block contents%} -<h2 class="heading">Select Genotypes Dataset</h2> - -<div class="row"> - <p>Your R/qtl2 files bundle contains a "geno" specification. You will - therefore need to select from one of the existing Genotype datasets or - create a new one.</p> - <p>This is the dataset where your data will be organised under.</p> -</div> - -<div class="row"> - <form id="frm-upload-rqtl2-bundle" - action="{{url_for('upload.rqtl2.select_geno_dataset', - species_id=species.SpeciesId, - population_id=population.InbredSetId)}}" - method="POST" - enctype="multipart/form-data"> - <legend class="heading">select from existing genotype datasets</legend> - - <input type="hidden" name="species_id" value="{{species.SpeciesId}}" /> - <input type="hidden" name="population_id" - value="{{population.InbredSetId}}" /> - <input type="hidden" name="rqtl2_bundle_file" - value="{{rqtl2_bundle_file}}" /> - - {{flash_messages("error-rqtl2-select-geno-dataset")}} - - <div class="form-group"> - <legend>Datasets</legend> - <label for="select:geno-datasets" class="form-label">Dataset</label> - <select id="select:geno-datasets" - name="geno-dataset-id" - required="required" - {%if datasets | length == 0%} - disabled="disabled" - {%endif%} - class="form-control" - aria-describedby="help-geno-dataset-select-dataset"> - <option value="">Select dataset</option> - {%for dset in datasets%} - <option value="{{dset['Id']}}">{{dset["Name"]}} ({{dset["FullName"]}})</option> - {%endfor%} - </select> - <span id="help-geno-dataset-select-dataset" class="form-text text-muted"> - Select from the existing genotype datasets for species - {{species.SpeciesName}} ({{species.FullName}}). - </span> - </div> - - <button type="submit" class="btn btn-primary">select dataset</button> - </form> -</div> - -<div class="row"> - <p style="color:#FE3535; padding-left:20em; font-weight:bolder;">OR</p> -</div> - -<div class="row"> - <form id="frm-upload-rqtl2-bundle" - action="{{url_for('upload.rqtl2.create_geno_dataset', - species_id=species.SpeciesId, - population_id=population.InbredSetId)}}" - method="POST" - enctype="multipart/form-data"> - <legend class="heading">create a new genotype dataset</legend> - - <input type="hidden" name="species_id" value="{{species.SpeciesId}}" /> - <input type="hidden" name="population_id" - value="{{population.InbredSetId}}" /> - <input type="hidden" name="rqtl2_bundle_file" - value="{{rqtl2_bundle_file}}" /> - - {{flash_messages("error-rqtl2-create-geno-dataset")}} - - <div class="form-group"> - <label for="txt:dataset-name" class="form-label">Name</label> - <input type="text" - id="txt:dataset-name" - name="dataset-name" - maxlength="100" - required="required" - class="form-control" - aria-describedby="help-geno-dataset-name" /> - <span id="help-geno-dataset-name" class="form-text text-muted"> - Provide the new name for the genotype dataset, e.g. "BXDGeno" - </span> - </div> - - <div class="form-group"> - <label for="txt:dataset-fullname" class="form-label">Full Name</label> - <input type="text" - id="txt:dataset-fullname" - name="dataset-fullname" - required="required" - maxlength="100" - class="form-control" - aria-describedby="help-geno-dataset-fullname" /> - - <span id="help-geno-dataset-fullname" class="form-text text-muted"> - Provide a longer name that better describes the genotype dataset, e.g. - "BXD Genotypes" - </span> - </div> - - <div class="form-group"> - <label for="txt:dataset-shortname" class="form-label">Short Name</label> - <input type="text" - id="txt:dataset-shortname" - name="dataset-shortname" - maxlength="100" - class="form-control" - aria-describedby="help-geno-dataset-shortname" /> - - <span id="help-geno-dataset-shortname" class="form-text text-muted"> - Provide a short name for the genotype dataset. This is optional. If not - provided, we'll default to the same value as the "Name" above. - </span> - </div> - - <div class="form-group"> - <input type="checkbox" - id="chk:dataset-public" - name="dataset-public" - checked="checked" - class="form-check" - aria-describedby="help-geno-datasent-public" /> - <label for="chk:dataset-public" class="form-check-label">Public?</label> - - <span id="help-geno-dataset-public" class="form-text text-muted"> - Specify whether the dataset will be available publicly. Check to make the - dataset publicly available and uncheck to limit who can access the dataset. - </span> - </div> - - <button type="submit" class="btn btn-primary">create new dataset</button> - </form> -</div> - -{%endblock%} diff --git a/uploader/templates/rqtl2/select-population.html b/uploader/templates/rqtl2/select-population.html deleted file mode 100644 index 37731f0..0000000 --- a/uploader/templates/rqtl2/select-population.html +++ /dev/null @@ -1,136 +0,0 @@ -{%extends "base.html"%} -{%from "flash_messages.html" import flash_messages%} - -{%block title%}Select Grouping/Population{%endblock%} - -{%block contents%} -<h1 class="heading">Select grouping/population</h1> - -<div class="explainer"> - <p>The data is organised in a hierarchical form, beginning with - <em>species</em> at the very top. Under <em>species</em> the data is - organised by <em>population</em>, sometimes referred to as <em>grouping</em>. - (In some really old documents/systems, you might see this referred to as - <em>InbredSet</em>.)</p> - <p>In this section, you get to define what population your data is to be - organised by.</p> -</div> - -<form method="POST" - action="{{url_for('upload.rqtl2.select_population', species_id=species.SpeciesId)}}"> - <legend class="heading">select grouping/population</legend> - {{flash_messages("error-select-population")}} - - <input type="hidden" name="species_id" value="{{species.SpeciesId}}" /> - - <div class="form-group"> - <label for="select:inbredset" class="form-label">population</label> - <select id="select:inbredset" - name="inbredset_id" - required="required" - class="form-control"> - <option value="">Select a grouping/population</option> - {%for pop in populations%} - <option value="{{pop.InbredSetId}}"> - {{pop.InbredSetName}} ({{pop.FullName}})</option> - {%endfor%} - </select> - <span class="form-text text-muted">If you are adding data to an already existing - population, simply pick the population from this drop-down selector. If - you cannot find your population from this list, try the form below to - create a new one..</span> - </div> - - <button type="submit" class="btn btn-primary" />select population</button> -</form> - -<p style="color:#FE3535; padding-left:20em; font-weight:bolder;">OR</p> - -<form method="POST" - action="{{url_for('upload.rqtl2.create_population', species_id=species.SpeciesId)}}"> - <legend class="heading">create new grouping/population</legend> - {{flash_messages("error-create-population")}} - - <input type="hidden" name="species_id" value="{{species.SpeciesId}}" /> - - <div class="form-group"> - <legend class="heading">mandatory</legend> - - <div class="form-group"> - <label for="txt:inbredset-name" class="form-label">name</label> - <input id="txt:inbredset-name" - name="inbredset_name" - type="text" - required="required" - maxlength="30" - placeholder="Enter grouping/population name" - class="form-control" /> - <span class="form-text text-muted">This is a short name that identifies the - population. Useful for menus, and quick scanning.</span> - </div> - - <div class="form-group"> - <label for="txt:" class="form-label">full name</label> - <input id="txt:inbredset-fullname" - name="inbredset_fullname" - type="text" - required="required" - maxlength="100" - placeholder="Enter the grouping/population's full name" - class="form-control" /> - <span class="form-text text-muted">This can be the same as the name above, or can - be longer. Useful for documentation, and human communication.</span> - </div> - </div> - - <div class="form-group"> - <legend class="heading">optional</legend> - - <div class="form-group"> - <label for="num:public" class="form-label">public?</label> - <select id="num:public" - name="public" - class="form-control"> - <option value="0">0 - Only accessible to authorised users</option> - <option value="1">1 - Publicly accessible to all users</option> - <option value="2" selected> - 2 - Publicly accessible to all users</option> - </select> - <span class="form-text text-muted">This determines whether the - population/grouping will appear on the menus for users.</span> - </div> - - <div class="form-group"> - <label for="txt:inbredset-family" class="form-label">family</label> - <input id="txt:inbredset-family" - name="inbredset_family" - type="text" - placeholder="I am not sure what this is about." - class="form-control" /> - <span class="form-text text-muted">I do not currently know what this is about. - This is a failure on my part to figure out what this is and provide a - useful description. Please feel free to remind me.</span> - </div> - - <div class="form-group"> - <label for="txtarea:" class="form-label">Description</label> - <textarea id="txtarea:description" - name="description" - rows="5" - placeholder="Enter a description of this grouping/population" - class="form-control"></textarea> - <span class="form-text text-muted"> - A long-form description of what the population consists of. Useful for - humans.</span> - </div> - </div> - - <button type="submit" class="btn btn-primary" /> - create grouping/population</button> -</form> - -{%endblock%} - - -{%block javascript%} -{%endblock%} diff --git a/uploader/templates/samples/base.html b/uploader/templates/samples/base.html new file mode 100644 index 0000000..291782b --- /dev/null +++ b/uploader/templates/samples/base.html @@ -0,0 +1,12 @@ +{%extends "populations/base.html"%} + +{%block lvl3_breadcrumbs%} +<li {%if activelink=="samples"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.samples.index')}}">Samples</a> +</li> +{%block lvl4_breadcrumbs%}{%endblock%} +{%endblock%} diff --git a/uploader/templates/samples/index.html b/uploader/templates/samples/index.html new file mode 100644 index 0000000..ee98734 --- /dev/null +++ b/uploader/templates/samples/index.html @@ -0,0 +1,23 @@ +{%extends "samples/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "species/macro-select-species.html" import select_species_form%} + +{%block title%}Populations{%endblock%} + +{%block pagetitle%}Populations{%endblock%} + + +{%block contents%} +{{flash_all_messages()}} + +<div class="row"> + <p>GeneNetwork has a selection of different species of organisms to choose from. Within those species, there are the populations of interest for a variety of experiments, from which you, the researcher, picked your samples (or individuals or cases) from. Here you can provide some basic details about your samples.</p> + <p>To start off, we will need to know what species and population your samples belong to. Please provide that information in the next sections.</p> + + {{select_species_form(url_for("species.populations.samples.index"), species)}} +</div> +{%endblock%} + +{%block javascript%} +<script type="text/javascript" src="/static/js/species.js"></script> +{%endblock%} diff --git a/uploader/templates/samples/list-samples.html b/uploader/templates/samples/list-samples.html new file mode 100644 index 0000000..185e784 --- /dev/null +++ b/uploader/templates/samples/list-samples.html @@ -0,0 +1,132 @@ +{%extends "samples/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "populations/macro-select-population.html" import select_population_form%} +{%from "populations/macro-display-population-card.html" import display_population_card%} + +{%block title%}Samples — List Samples{%endblock%} + +{%block pagetitle%}Samples — List Samples{%endblock%} + +{%block lvl4_breadcrumbs%} +<li {%if activelink=="list-samples"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.samples.list_samples', + species_id=species.SpeciesId, + population_id=population.Id)}}">List</a> +</li> +{%endblock%} + +{%block contents%} +{{flash_all_messages()}} + +<div class="row"> + <p> + You selected the population "{{population.FullName}}" from the + "{{species.FullName}}" species. + </p> +</div> + +{%if samples | length > 0%} +<div class="row"> + <p> + This population already has <strong>{{total_samples}}</strong> + samples/individuals entered. You can explore the list of samples in this + population in the table below. + </p> +</div> + +<div class="row"> + <div class="col-md-2"> + {%if offset > 0:%} + <a href="{{url_for('species.populations.samples.list_samples', + species_id=species.SpeciesId, + population_id=population.Id, + from=offset-count, + count=count)}}"> + <span class="glyphicon glyphicon-backward"></span> + Previous + </a> + {%endif%} + </div> + + <div class="col-md-8" style="text-align: center;"> + Samples {{offset}} — {{offset+(count if offset + count < total_samples else total_samples - offset)}} / {{total_samples}} + </div> + + <div class="col-md-2"> + {%if offset + count < total_samples:%} + <a href="{{url_for('species.populations.samples.list_samples', + species_id=species.SpeciesId, + population_id=population.Id, + from=offset+count, + count=count)}}"> + Next + <span class="glyphicon glyphicon-forward"></span> + </a> + {%endif%} + </div> +</div> +<div class="row"> + <table class="table"> + <thead> + <tr> + <th></th> + <th>Name</th> + <th>Auxilliary Name</th> + <th>Symbol</th> + <th>Alias</th> + </tr> + </thead> + + <tbody> + {%for sample in samples%} + <tr> + <td>{{sample.sequence_number}}</td> + <td>{{sample.Name}}</td> + <td>{{sample.Name2}}</td> + <td>{{sample.Symbol or "-"}}</td> + <td>{{sample.Alias or "-"}}</td> + </tr> + {%endfor%} + </tbody> + </table> + + <p> + <a href="#" + title="Add samples for population '{{population.FullName}}' from species + '{{species.FullName}}'." + class="btn btn-danger"> + delete all samples + </a> + </p> +</div> + +{%else%} + +<div class="row"> + <p> + There are no samples entered for this population. Do please go ahead and add + the samples for this population by clicking on the button below. + </p> + + <p> + <a href="{{url_for('species.populations.samples.upload_samples', + species_id=species.SpeciesId, + population_id=population.Id)}}" + title="Add samples for population '{{population.FullName}}' from species + '{{species.FullName}}'." + class="btn btn-primary"> + add samples + </a> + </p> +</div> +{%endif%} + +{%endblock%} + +{%block sidebarcontents%} +{{display_population_card(species, population)}} +{%endblock%} diff --git a/uploader/templates/samples/select-population.html b/uploader/templates/samples/select-population.html index da19ddc..1cc7573 100644 --- a/uploader/templates/samples/select-population.html +++ b/uploader/templates/samples/select-population.html @@ -1,99 +1,26 @@ -{%extends "base.html"%} -{%from "flash_messages.html" import flash_messages%} +{%extends "samples/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "populations/macro-select-population.html" import select_population_form%} +{%from "species/macro-display-species-card.html" import display_species_card%} -{%block title%}Select Grouping/Population{%endblock%} +{%block title%}Samples — Select Population{%endblock%} -{%block contents%} -<h1 class="heading">Select grouping/population</h1> - -<div> - <p>We organise the samples/cases/strains in a hierarchichal form, starting - with <strong>species</strong> at the very top. Under species, we have a - grouping in terms of the relevant population - (e.g. Inbred populations, cell tissue, etc.)</p> -</div> - -<form method="POST" action="{{url_for('samples.select_population', - species_id=species.SpeciesId)}}"> - <legend class="heading">select grouping/population</legend> - {{flash_messages("error-select-population")}} - - <input type="hidden" name="species_id" value="{{species.SpeciesId}}" /> - - <div class="form-group"> - <label for="select:inbredset" class="form-label">grouping/population</label> - <select id="select:inbredset" - name="inbredset_id" - required="required" - class="form-control"> - <option value="">Select a grouping/population</option> - {%for pop in populations%} - <option value="{{pop.InbredSetId}}"> - {{pop.InbredSetName}} ({{pop.FullName}})</option> - {%endfor%} - </select> - </div> - - <button type="submit" class="btn btn-primary">select population</button> -</form> - -<p style="color:#FE3535; padding-left:20em; font-weight:bolder;">OR</p> - -<form method="POST" action="{{url_for('samples.create_population', - species_id=species.SpeciesId)}}"> - <legend class="heading">create new grouping/population</legend> - {{flash_messages("error-create-population")}} +{%block pagetitle%}Samples — Select Population{%endblock%} - <input type="hidden" name="species_id" value="{{species.SpeciesId}}" /> - <div class="form-group"> - <legend>mandatory</legend> - <label for="txt:inbredset-name" class="form-label">name</label> - <input id="txt:inbredset-name" - name="inbredset_name" - type="text" - required="required" - placeholder="Enter grouping/population name" - class="form-control" /> - - <label for="txt:" class="form-label">full name</label> - <input id="txt:inbredset-fullname" - name="inbredset_fullname" - type="text" - required = "required" - placeholder="Enter the grouping/population's full name" - class="form-control" /> - </div> - <div class="form-group"> - <legend>Optional</legend> - - <label for="num:public" class="form-label">public?</label> - <input id="num:public" - name="public" - type="number" - min="0" max="2" value="2" - class="form-control" /> - - <label for="txt:inbredset-family" class="form-label">family</label> - <input id="txt:inbredset-family" - name="inbredset_family" - type="text" - placeholder="I am not sure what this is about." - class="form-control" /> - - <label for="txtarea:" class="form-label">Description</label> - <textarea id="txtarea:description" - name="description" - rows="5" - placeholder="Enter a description of this grouping/population" - class="form-control"></textarea> - </div> - - <button type="submit" class="btn btn-primary">create grouping/population</button> -</form> +{%block contents%} +{{flash_all_messages()}} +<div class="row"> + {{select_population_form( + url_for("species.populations.samples.select_population", species_id=species.SpeciesId), species, populations)}} +</div> {%endblock%} +{%block sidebarcontents%} +{{display_species_card(species)}} +{%endblock%} {%block javascript%} +<script type="text/javascript" src="/static/js/populations.js"></script> {%endblock%} diff --git a/uploader/templates/samples/select-species.html b/uploader/templates/samples/select-species.html deleted file mode 100644 index edadc61..0000000 --- a/uploader/templates/samples/select-species.html +++ /dev/null @@ -1,30 +0,0 @@ -{%extends "base.html"%} -{%from "flash_messages.html" import flash_all_messages%} - -{%block title%}Select Grouping/Population{%endblock%} - -{%block contents%} -<h2 class="heading">upload samples/cases</h2> - -<p>We need to know what species your data belongs to.</p> - -{{flash_all_messages()}} - -<form method="POST" action="{{url_for('samples.select_species')}}"> - <legend class="heading">upload samples</legend> - <div class="form-group"> - <label for="select_species02" class="form-label">Species</label> - <select id="select_species02" - name="species_id" - required="required" - class="form-control"> - <option value="">Select species</option> - {%for spec in species%} - <option value="{{spec.SpeciesId}}">{{spec.MenuName}}</option> - {%endfor%} - </select> - </div> - - <button type="submit" class="btn btn-primary">submit</button> -</form> -{%endblock%} diff --git a/uploader/templates/samples/upload-failure.html b/uploader/templates/samples/upload-failure.html index 09e2ecf..2cf8053 100644 --- a/uploader/templates/samples/upload-failure.html +++ b/uploader/templates/samples/upload-failure.html @@ -1,10 +1,12 @@ {%extends "base.html"%} {%from "cli-output.html" import cli_output%} +{%from "populations/macro-display-population-card.html" import display_population_card%} {%block title%}Samples Upload Failure{%endblock%} {%block contents%} -<h1 class="heading">{{job.job_name}}</h2> +<div class="row"> +<h2 class="heading">{{job.job_name[0:50]}}…</h2> <p>There was a failure attempting to upload the samples.</p> @@ -13,15 +15,23 @@ <h3>Debugging Information</h3> <ul> - <li><strong>job id</strong>: {{job.job_id}}</li> + <li><strong>job id</strong>: {{job.jobid}}</li> <li><strong>status</strong>: {{job.status}}</li> <li><strong>job type</strong>: {{job["job-type"]}}</li> </ul> +</div> +<div class="row"> <h4>stdout</h4> {{cli_output(job, "stdout")}} +</div> +<div class="row"> <h4>stderr</h4> {{cli_output(job, "stderr")}} +</div> +{%endblock%} +{%block sidebarcontents%} +{{display_population_card(species, population)}} {%endblock%} diff --git a/uploader/templates/samples/upload-progress.html b/uploader/templates/samples/upload-progress.html index 7bb02be..677d457 100644 --- a/uploader/templates/samples/upload-progress.html +++ b/uploader/templates/samples/upload-progress.html @@ -1,5 +1,6 @@ -{%extends "base.html"%} +{%extends "samples/base.html"%} {%from "cli-output.html" import cli_output%} +{%from "populations/macro-display-population-card.html" import display_population_card%} {%block extrameta%} <meta http-equiv="refresh" content="5"> @@ -8,7 +9,8 @@ {%block title%}Job Status{%endblock%} {%block contents%} -<h1 class="heading">{{job.job_name}}</h2> +<div class="row" style="overflow-x: clip;"> +<h2 class="heading">{{job.job_name[0:50]}}…</h2> <p> <strong>status</strong>: @@ -16,7 +18,14 @@ </p> <p>saving to database...</p> +</div> -{{cli_output(job, "stdout")}} +<div class="row"> + {{cli_output(job, "stdout")}} +</div> {%endblock%} + +{%block sidebarcontents%} +{{display_population_card(species, population)}} +{%endblock%} diff --git a/uploader/templates/samples/upload-samples.html b/uploader/templates/samples/upload-samples.html index e62de57..25d3290 100644 --- a/uploader/templates/samples/upload-samples.html +++ b/uploader/templates/samples/upload-samples.html @@ -1,138 +1,159 @@ -{%extends "base.html"%} -{%from "flash_messages.html" import flash_messages%} - -{%block title%}Upload Samples{%endblock%} - -{%block css%}{%endblock%} +{%extends "samples/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} +{%from "populations/macro-select-population.html" import select_population_form%} +{%from "populations/macro-display-population-card.html" import display_population_card%} + +{%block title%}Samples — Upload Samples{%endblock%} + +{%block pagetitle%}Samples — Upload Samples{%endblock%} + +{%block lvl4_breadcrumbs%} +<li {%if activelink=="uploade-samples"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.populations.samples.upload_samples', + species_id=species.SpeciesId, + population_id=population.Id)}}">List</a> +</li> +{%endblock%} {%block contents%} -<h1 class="heading">upload samples</h1> - -{{flash_messages("alert-success")}} - -<p>You can now upload a character-separated value (CSV) file that contains - details about your samples. The CSV file should have the following fields: - <dl> - <dt>Name</dt> - <dd>The primary name for the sample</dd> - - <dt>Name2</dt> - <dd>A secondary name for the sample. This can simply be the same as - <strong>Name</strong> above. This field <strong>MUST</strong> contain a - value.</dd> - - <dt>Symbol</dt> - <dd>A symbol for the sample. Can be an empty field.</dd> - - <dt>Alias</dt> - <dd>An alias for the sample. Can be an empty field.</dd> - </dl> -</p> - -<form id="form-samples" - method="POST" - action="{{url_for('samples.upload_samples', - species_id=species.SpeciesId, - population_id=population.InbredSetId)}}" - enctype="multipart/form-data"> - <legend class="heading">upload samples</legend> - - <div class="form-group"> - <input type="hidden" name="species_id" value="{{species.SpeciesId}}" /> - <label class="form-label">species:</label> - <span class="form-text">{{species.SpeciesName}} [{{species.MenuName}}]</span> - </div> - - <div class="form-group"> - <input type="hidden" name="inbredset_id" value="{{population.InbredSetId}}" /> - <label class="form-label">grouping/population:</label> - <span class="form-text">{{population.Name}} [{{population.FullName}}]</span> - </div> - - <div class="form-group"> - <label for="file-samples" class="form-label">select file</label> - <input type="file" name="samples_file" id="file:samples" - accept="text/csv, text/tab-separated-values" - class="form-control" /> - </div> - - <div class="form-group"> - <label for="select:separator" class="form-label">field separator</label> - <select id="select:separator" - name="separator" - required="required" - class="form-control"> - <option value="">Select separator for your file: (default is comma)</option> - <option value="	">TAB</option> - <option value=" ">Space</option> - <option value=",">Comma</option> - <option value=";">Semicolon</option> - <option value="other">Other</option> - </select> - <input id="txt:separator" - type="text" - name="other_separator" - class="form-control" /> - <small class="form-text text-muted"> - If you select '<strong>Other</strong>' for the field separator value, - enter the character that separates the fields in your CSV file in the form - field below. - </small> - </div> - - <div class="form-group form-check"> - <input id="chk:heading" - type="checkbox" - name="first_line_heading" - class="form-check-input" /> - <label for="chk:heading" class="form-check-label"> - first line is a heading?</label> - <small class="form-text text-muted"> - Select this if the first line in your file contains headings for the - columns. - </small> - </div> - - <div class="form-group"> - <label for="txt:delimiter" class="form-label">field delimiter</label> - <input id="txt:delimiter" - type="text" - name="field_delimiter" - maxlength="1" - class="form-control" /> - <small class="form-text text-muted"> - If there is a character delimiting the string texts within particular - fields in your CSV, provide the character here. This can be left blank if - no such delimiters exist in your file. - </small> - </div> - - <button type="submit" - class="btn btn-primary">upload samples file</button> -</form> - -<table id="tbl:samples-preview" class="table"> - <caption class="heading">preview content</caption> - - <thead> - <tr> - <th>Name</th> - <th>Name2</th> - <th>Symbol</th> - <th>Alias</th> - </tr> - </thead> - - <tbody> - <tr id="default-row"> - <td colspan="4"> - Please make some selections to preview the data.</td> - </tr> - </tbody> -</table> +{{flash_all_messages()}} + +<div class="row"> + <p> + You can now upload the samples for the "{{population.FullName}}" population + from the "{{species.FullName}}" species here. + </p> + <p> + Upload a <strong>character-separated value (CSV)</strong> file that contains + details about your samples. The CSV file should have the following fields: + <dl> + <dt>Name</dt> + <dd>The primary name/identifier for the sample/individual.</dd> + + <dt>Name2</dt> + <dd>A secondary name for the sample. This can simply be the same as + <strong>Name</strong> above. This field <strong>MUST</strong> contain a + value.</dd> + + <dt>Symbol</dt> + <dd>A symbol for the sample. This can be a strain name, e.g. 'BXD60' for + species that have strains. This field can be left empty for species like + Humans that do not have strains..</dd> + + <dt>Alias</dt> + <dd>An alias for the sample. Can be an empty field, or take on the same + value as that of the Symbol.</dd> + </dl> + </p> +</div> + +<div class="row"> + <form id="form-samples" + method="POST" + action="{{url_for('species.populations.samples.upload_samples', + species_id=species.SpeciesId, + population_id=population.InbredSetId)}}" + enctype="multipart/form-data"> + <legend class="heading">upload samples</legend> + <input type="hidden" name="species_id" value="{{species.SpeciesId}}" /> + <input type="hidden" name="population_id" value="{{population.Id}}" /> + + <div class="form-group"> + <label for="file-samples" class="form-label">select file</label> + <input type="file" name="samples_file" id="file:samples" + accept="text/csv, text/tab-separated-values" + class="form-control" /> + </div> + + <div class="form-group"> + <label for="select:separator" class="form-label">field separator</label> + <select id="select:separator" + name="separator" + required="required" + class="form-control"> + <option value="">Select separator for your file: (default is comma)</option> + <option value="	">TAB</option> + <option value=" ">Space</option> + <option value=",">Comma</option> + <option value=";">Semicolon</option> + <option value="other">Other</option> + </select> + <input id="txt:separator" + type="text" + name="other_separator" + class="form-control" /> + <small class="form-text text-muted"> + If you select '<strong>Other</strong>' for the field separator value, + enter the character that separates the fields in your CSV file in the form + field below. + </small> + </div> + + <div class="form-group form-check"> + <input id="chk:heading" + type="checkbox" + name="first_line_heading" + class="form-check-input" /> + <label for="chk:heading" class="form-check-label"> + first line is a heading?</label> + <small class="form-text text-muted"> + Select this if the first line in your file contains headings for the + columns. + </small> + </div> + + <div class="form-group"> + <label for="txt:delimiter" class="form-label">field delimiter</label> + <input id="txt:delimiter" + type="text" + name="field_delimiter" + maxlength="1" + class="form-control" /> + <small class="form-text text-muted"> + If there is a character delimiting the string texts within particular + fields in your CSV, provide the character here. This can be left blank if + no such delimiters exist in your file. + </small> + </div> + + <button type="submit" + class="btn btn-primary">upload samples file</button> + </form> +</div> + +<div class="row"> + <h3>Preview File Content</h3> + + <table id="tbl:samples-preview" class="table"> + <caption class="heading">preview content</caption> + + <thead> + <tr> + <th>Name</th> + <th>Name2</th> + <th>Symbol</th> + <th>Alias</th> + </tr> + </thead> + + <tbody> + <tr id="default-row"> + <td colspan="4"> + Please make some selections in the form above to preview the data.</td> + </tr> + </tbody> + </table> +</div> {%endblock%} +{%block sidebarcontents%} +{{display_population_card(species, population)}} +{%endblock%} {%block javascript%} <script src="/static/js/upload_samples.js" type="text/javascript"></script> diff --git a/uploader/templates/samples/upload-success.html b/uploader/templates/samples/upload-success.html index cb745c3..881d466 100644 --- a/uploader/templates/samples/upload-success.html +++ b/uploader/templates/samples/upload-success.html @@ -1,18 +1,36 @@ -{%extends "base.html"%} +{%extends "samples/base.html"%} {%from "cli-output.html" import cli_output%} +{%from "populations/macro-display-population-card.html" import display_population_card%} {%block title%}Job Status{%endblock%} {%block contents%} -<h1 class="heading">{{job.job_name}}</h2> -<p> -<strong>status</strong>: -<span>{{job["status"]}} ({{job.get("message", "-")}})</span><br /> -</p> +<div class="row" style="overflow-x: clip;"> + <h2 class="heading">{{job.job_name[0:50]}}…</h2> -<p>Successfully uploaded the samples.</p> + <p> + <strong>status</strong>: + <span>{{job["status"]}} ({{job.get("message", "-")}})</span><br /> + </p> -{{cli_output(job, "stdout")}} + <p>Successfully uploaded the samples.</p> + <p> + <a href="{{url_for('species.populations.samples.list_samples', + species_id=species.SpeciesId, + population_id=population.Id)}}" + title="View population samples"> + View samples + </a> + </p> +</div> +<div class="row"> + {{cli_output(job, "stdout")}} +</div> + +{%endblock%} + +{%block sidebarcontents%} +{{display_population_card(species, population)}} {%endblock%} diff --git a/uploader/templates/select_species.html b/uploader/templates/select_species.html deleted file mode 100644 index 3b1a8a9..0000000 --- a/uploader/templates/select_species.html +++ /dev/null @@ -1,92 +0,0 @@ -{%extends "base.html"%} -{%from "flash_messages.html" import flash_messages%} -{%from "upload_progress_indicator.html" import upload_progress_indicator%} - -{%block title%}expression data: select species{%endblock%} - -{%block contents%} -{{upload_progress_indicator()}} - -<h2 class="heading">expression data: select species</h2> - -<div class="row"> - <form action="{{url_for('entry.upload_file')}}" - method="POST" - enctype="multipart/form-data" - id="frm-upload-expression-data"> - <legend class="heading">upload expression data</legend> - {{flash_messages("error-expr-data")}} - - <div class="form-group"> - <label for="select_species01" class="form-label">Species</label> - <select id="select_species01" - name="speciesid" - required="required" - class="form-control"> - <option value="">Select species</option> - {%for aspecies in species%} - <option value="{{aspecies.SpeciesId}}">{{aspecies.MenuName}}</option> - {%endfor%} - </select> - </div> - - <div class="form-group"> - <legend class="heading">file type</legend> - - <div class="form-check"> - <input type="radio" name="filetype" value="average" id="filetype_average" - required="required" class="form-check-input" /> - <label for="filetype_average" class="form-check-label">average</label> - </div> - - <div class="form-check"> - <input type="radio" name="filetype" value="standard-error" - id="filetype_standard_error" required="required" - class="form-check-input" /> - <label for="filetype_standard_error" class="form-check-label"> - standard error - </label> - </div> - </div> - - <div class="form-group"> - <span id="no-file-error" class="alert-danger" style="display: none;"> - No file selected - </span> - <label for="file_upload" class="form-label">select file</label> - <input type="file" name="qc_text_file" id="file_upload" - accept="text/plain, text/tab-separated-values, application/zip" - class="form-control"/> - </div> - - <button type="submit" - class="btn btn-primary" - data-toggle="modal" - data-target="#upload-progress-indicator">upload file</button> - </form> -</div> -{%endblock%} - - -{%block javascript%} -<script type="text/javascript" src="static/js/upload_progress.js"></script> -<script type="text/javascript"> - function setup_formdata(form) { - var formdata = new FormData(); - formdata.append( - "speciesid", - form.querySelector("#select_species01").value) - formdata.append( - "qc_text_file", - form.querySelector("input[type='file']").files[0]); - formdata.append( - "filetype", - selected_filetype( - Array.from(form.querySelectorAll("input[type='radio']")))); - return formdata; - } - - setup_upload_handlers( - "frm-upload-expression-data", make_data_uploader(setup_formdata)); -</script> -{%endblock%} diff --git a/uploader/templates/species/base.html b/uploader/templates/species/base.html new file mode 100644 index 0000000..f64f72b --- /dev/null +++ b/uploader/templates/species/base.html @@ -0,0 +1,17 @@ +{%extends "base.html"%} + +{%block lvl1_breadcrumbs%} +<li {%if activelink=="species"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + {%if species is mapping%} + <a href="{{url_for('species.view_species', species_id=species.SpeciesId)}}"> + {{species.Name}}</a> + {%else%} + <a href="{{url_for('species.list_species')}}">Species</a> + {%endif%} +</li> +{%block lvl2_breadcrumbs%}{%endblock%} +{%endblock%} diff --git a/uploader/templates/species/create-species.html b/uploader/templates/species/create-species.html new file mode 100644 index 0000000..138dbaa --- /dev/null +++ b/uploader/templates/species/create-species.html @@ -0,0 +1,148 @@ +{%extends "species/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} + +{%block title%}Create Species{%endblock%} + +{%block pagetitle%}Create Species{%endblock%} + +{%block lvl2_breadcrumbs%} +<li {%if activelink=="create-species"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.create_species')}}">Create</a> +</li> +{%endblock%} + +{%block contents%} +<div class="row"> + <form id="frm-create-species" + method="POST" + action="{{url_for('species.create_species', return_to=return_to)}}" + class="form-horizontal"> + <legend>Create Species</legend> + + {{flash_all_messages()}} + + <input type="hidden" name="return_to" value="{{return_to}}"> + + <div class="form-group"> + <label for="txt-taxonomy-id" class="control-label col-sm-2"> + Taxonomy ID</label> + <div class="col-sm-10"> + <div class="input-group"> + <input id="txt-taxonomy-id" + name="species_taxonomy_id" + type="text" + class="form-control" /> + <span class="input-group-btn"> + <button id="btn-search-taxonid" class="btn btn-info">Search</button> + </span> + </div> + <small class="form-text text-small text-muted"> + Use + <a href="https://www.ncbi.nlm.nih.gov/Taxonomy/taxonomyhome.html/" + title="NCBI's Taxonomy Browser homepage" + target="_blank"> + NCBI's Taxonomy Browser homepage</a> to search for the species you + want. If the species exists on NCBI, they will have a Taxonomy ID. Copy + that Taxonomy ID to this field, and click "Search" to auto-fill the + details.<br /> + This field is optional.</small> + </div> + </div> + + <div class="form-group"> + <label for="txt-species-name" class="control-label col-sm-2">Common Name</label> + <div class="col-sm-10"> + <input id="txt-species-name" + name="common_name" + type="text" + class="form-control" + required="required" /> + <small class="form-text text-muted">This is the day-to-day term used by + laymen, e.g. Mouse (instead of Mus musculus), round worm (instead of + Ascaris lumbricoides), etc.<br /> + For species without this, just enter the scientific name. + </small> + </div> + </div> + + <div class="form-group"> + <label for="txt-species-scientific" class="control-label col-sm-2"> + Scientific Name</label> + <div class="col-sm-10"> + <input id="txt-species-scientific" + name="scientific_name" + type="text" + class="form-control" + required="required" /> + <small class="form-text text-muted">This is the scientific name for the + species e.g. Homo sapiens, Mus musculus, etc.</small> + </div> + </div> + + <div class="form-group"> + <label for="select-species-family" class="control-label col-sm-2">Family</label> + <div class="col-sm-10"> + <select id="select-species-family" + name="species_family" + required="required" + class="form-control"> + <option value="ungrouped">I do not know what to pick</option> + {%for family in families%} + <option value="{{family}}">{{family}}</option> + {%endfor%} + </select> + <small class="form-text text-muted"> + This is a rough grouping of the species.</small> + </div> + </div> + + <div class="col-sm-offset-2 col-sm-10"> + <input type="submit" + value="create new species" + class="btn btn-primary" /> + </div> + + </form> +</div> +{%endblock%} + +{%block javascript%} +<script> + var lastTaxonId = null; + + var fetch_taxonomy = (taxonId) => { + var uri = ( + "https://rest.uniprot.org/taxonomy/" + encodeURIComponent(taxonId)); + $.get( + uri, + {}, + (data, textStatus, jqXHR) => { + if(textStatus == "success") { + lastTaxonId = taxonId; + $("#txt-species-scientific").val(data.scientificName); + $("#txt-species-name").val(data.commonName); + return false; + } + msg = ( + "Request to '${uri}' failed with message '${textStatus}'. " + + "Please try again later, or fill the details manually."); + alert(msg); + console.error(msg, data, textStatus); + return false; + }, + "json"); + }; + + $("#btn-search-taxonid").on("click", (event) => { + event.preventDefault(); + taxonId = $("#txt-taxonomy-id").val(); + if((taxonId !== "") && (taxonId !== lastTaxonId)) { + fetch_taxonomy(taxonId); + } + }); +</script> +{%endblock%} diff --git a/uploader/templates/species/edit-species.html b/uploader/templates/species/edit-species.html new file mode 100644 index 0000000..5a26455 --- /dev/null +++ b/uploader/templates/species/edit-species.html @@ -0,0 +1,177 @@ +{%extends "species/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} + +{%block title%}Edit Species{%endblock%} + +{%block pagetitle%}Edit Species{%endblock%} + +{%block css%} +<style type="text/css"> + .card { + margin-top: 0.3em; + border-width: 1px; + border-style: solid; + border-radius: 0.3em; + border-color: #AAAAAA; + padding: 0.5em; + } +</style> +{%endblock%} + +{%block lvl2_breadcrumbs%} +<li {%if activelink=="edit-species"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.edit_species_extra', + species_id=species.SpeciesId)}}">Edit</a> +</li> +{%endblock%} + +{%block contents%} +{{flash_all_messages()}} +<div class="row"> + <form id="frm-edit-species" + method="POST" + action="{{url_for('species.edit_species_extra', + species_id=species.SpeciesId)}}"> + + <legend>Edit Extra Detail for Species '{{species.FullName}}'</legend> + + <input type="hidden" name="species_id" value="{{species.SpeciesId}}" /> + + <div class="form-group"> + <label for="lbl-species-taxonid" class="form-label"> + Taxonomy Id + </label> + <label id="lbl-species-taxonid" + disabled="disabled" + class="form-control">{{species.TaxonomyId}}</label> + </div> + + <div class="form-group"> + <label for="txt-species-name" class="form-label"> + Common Name + </label> + <input type="text" + id="txt-species-name" + name="species_name" + required="required" + value="{{species.SpeciesName}}" + class="form-control" /> + <small class="form-text text-muted"> + This is the layman's name for the species, e.g. mouse</mall> + </div> + + <div class="form-group"> + <label for="txt-species-fullname" class="form-label"> + Scientific Name + </label> + <input type="text" + id="txt-species-fullname" + name="species_fullname" + required="required" + value="{{species.FullName}}" + class="form-control" /> + <small class="form-text text-muted"> + A scientific name for the species that mostly adheres to the biological + binomial nomenclature system.</small> + </div> + + <div class="form-group"> + <label for="select-species-family" class="form-label"> + Family + </label> + <select id="select-species-family" + name="species_family" + class="form-control"> + <option value="">Select the family</option> + {%for family in families%} + <option value="{{family}}" + {%if species.Family == family%} + selected="selected" + {%endif%}>{{family}}</option> + {%endfor%} + </select> + <small class="form-text text-muted"> + A general classification for the species. This is mostly for use in + GeneNetwork's menus.</small> + </div> + + <div class="form-group"> + <label for="txt-species-familyorderid" class="form-label"> + Family Order Id + </label> + <input type="number" + id="txt-species-familyorderid" + name="species_familyorderid" + value="{{species.FamilyOrderId}}" + required="required" + class="form-control" /> + <small class="form-text text-muted"> + This is a number that determines the order of the "Family" groupings + above in the GeneNetwork menus. This is an integer value that's manually + assigned.</small> + </div> + + <div class="form-group"> + <label for="txt-species-orderid" class="form-label"> + Order Id + </label> + <input type="number" + id="txt-species-orderid" + name="species_orderid" + value="{{species.OrderId or (max_order_id + 5)}}" + class="form-control" /> + <small class="form-text text-muted"> + This integer value determines the order of the species in relation to + each other, but also within the respective "Family" groups.</small> + </div> + + <div class="form-group"> + <input type="submit" value="Submit Changes" class="btn btn-primary" /> + </div> + + </form> +</div> +{%endblock%} + +{%block sidebarcontents%} + +<div class="card"> + <div class="card-body"> + <h5 class="card-title">Family Order</h5> + <div class="card-text"> + <p>The current family order is as follows</p> + <table class="table"> + <thead> + <tr> + <th>Family Order Id</th> + <th>Family</th> + </tr> + </thead> + <tbody> + {%for item in family_order%} + <tr> + <td>{{item[0]}}</td> + <td>{{item[1]}}</td> + </tr> + {%endfor%} + </tbody> + </table> + </div> + </div> +</div> + +<div class="card"> + <div class="card-body"> + <h5 class="card-title">Order ID</h5> + <div class="card-text"> + <p>The current largest OrderID is: {{max_order_id}}</p> + <p>We recommend giving a new species an order ID that is five more than + the current highest i.e. {{max_order_id + 5}}.</p> + </div> + </div> +</div> +{%endblock%} diff --git a/uploader/templates/species/list-species.html b/uploader/templates/species/list-species.html new file mode 100644 index 0000000..64084b0 --- /dev/null +++ b/uploader/templates/species/list-species.html @@ -0,0 +1,75 @@ +{%extends "species/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} + +{%block title%}List Species{%endblock%} + +{%block pagetitle%}List Species{%endblock%} + +{%block contents%} +{{flash_all_messages()}} +<div class="row"> + <p> + All data in GeneNetwork revolves around species. This is the core of the + system.</p> + <p>Here you can see a list of all the species available in GeneNetwork. + Click on the link besides each species to view greater detail on the species, + and access further operations that are possible for said species.</p> +</div> + +<div class="row"> + <p>If you cannot find the species you are looking for below, click the button + below to create it</p> + <p><a href="{{url_for('species.create_species')}}" + title="Add a new species to GeneNetwork" + class="btn btn-danger">Create Species</a></p> +</div> + +<div class="row"> + <table class="table"> + <caption>Available Species</caption> + <thead> + <tr> + <th></td> + <th title="A common, layman's name for the species.">Common Name</th> + <th title="The scientific name for the species">Organism Name</th> + <th title="An identifier for the species in the NCBI taxonomy database"> + Taxonomy ID + </th> + <th title="A generic grouping used internally by GeneNetwork for organising species."> + Family + </th> + </tr> + </thead> + <tbody> + {%for species in allspecies%} + <tr> + <td>{{species["sequence_number"]}}</td> + <td>{{species["SpeciesName"]}}</td> + <td> + <a href="{{url_for('species.view_species', + species_id=species['SpeciesId'])}}" + title="View details in GeneNetwork on {{species['FullName']}}"> + {{species["FullName"]}} + </a> + </td> + <td> + <a href="https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id={{species['TaxonomyId']}}" + title="View species details on NCBI" + target="_blank">{{species["TaxonomyId"]}}</a> + </td> + <td>{{species.Family}}</td> + </tr> + {%else%} + <tr> + <td colspan="3"> + <p class="text-danger"> + <span class="glyphicon glyphicon-exclamation-mark"></span> + There were no species found! + </p> + </td> + </tr> + {%endfor%} + </tbody> + </table> +</div> +{%endblock%} diff --git a/uploader/templates/species/macro-display-species-card.html b/uploader/templates/species/macro-display-species-card.html new file mode 100644 index 0000000..166c7b9 --- /dev/null +++ b/uploader/templates/species/macro-display-species-card.html @@ -0,0 +1,22 @@ +{%macro display_species_card(species)%} +<div class="card"> + <div class="card-body"> + <h5 class="card-title">Species</h5> + <div class="card-text"> + <table class="table"> + <tbody> + <tr> + <td>Common Name</td> + <td>{{species.SpeciesName}}</td> + </tr> + + <tr> + <td>Scientific Name</td> + <td>{{species.FullName}}</td> + </tr> + </tbody> + </table> + </div> + </div> +</div> +{%endmacro%} diff --git a/uploader/templates/species/macro-select-species.html b/uploader/templates/species/macro-select-species.html new file mode 100644 index 0000000..3714ae4 --- /dev/null +++ b/uploader/templates/species/macro-select-species.html @@ -0,0 +1,59 @@ +{%from "macro-step-indicator.html" import step_indicator%} + +{%macro select_species_form(form_action, species)%} +<form method="GET" action="{{form_action}}" class="form-horizontal"> + + <h2>{{step_indicator("1")}} What species do you want to work with?</h2> + + {%if species | length != 0%} + + <p class="form-text">Search for, and select the species from the table below + and click "Continue"</p> + + <div class="radio"> + <label for="rdo-cant-find-species" + style="font-weight: 1;"> + <input id="rdo-cant-find-species" type="radio" name="species_id" + value="CREATE-SPECIES" /> + I could not find the species I want (create it). + </label> + </div> + + <div class="col-sm-offset-10 col-sm-2"> + <input type="submit" + class="btn btn-primary" + value="continue" /> + </div> + + <div style="margin-top:3em;"> + <table id="tbl-select-species" class="table compact stripe" + data-species-list='{{species | tojson}}'> + <div class=""> + <thead> + <tr> + <th></th> + <th>Species Name</th> + </tr> + </thead> + + <tbody></tbody> + </table> + </div> + + {%else%} + + <label class="control-label" for="rdo-cant-find-species"> + <input id="rdo-cant-find-species" type="radio" name="species_id" + value="CREATE-SPECIES" /> + There are no species to select from. Create the first one.</label> + + <div class="col-sm-offset-10 col-sm-2"> + <input type="submit" + class="btn btn-primary col-sm-offset-1" + value="continue" /> + </div> + + {%endif%} + +</form> +{%endmacro%} diff --git a/uploader/templates/species/view-species.html b/uploader/templates/species/view-species.html new file mode 100644 index 0000000..2d02f7e --- /dev/null +++ b/uploader/templates/species/view-species.html @@ -0,0 +1,90 @@ +{%extends "species/base.html"%} +{%from "flash_messages.html" import flash_all_messages%} + +{%block title%}View Species{%endblock%} + +{%block pagetitle%}View Species{%endblock%} + +{%block lvl2_breadcrumbs%} +<li {%if activelink=="view-species"%} + class="breadcrumb-item active" + {%else%} + class="breadcrumb-item" + {%endif%}> + <a href="{{url_for('species.view_species', species_id=species.SpeciesId)}}">View</a> +</li> +{%endblock%} + +{%block contents%} +{{flash_all_messages()}} +<div class="row"> + <h2>Details on species {{species.FullName}}</h2> + + <dl> + <dt>Common Name</dt> + <dd>{{species.SpeciesName}}</dd> + + <dt>Scientific Name</dt> + <dd>{{species.FullName}}</dd> + + <dt>Taxonomy ID</dt> + <dd>{{species.TaxonomyId}}</dd> + </dl> + + <h3>Actions</h3> + + <p> + You can proceed to perform any of the following actions for species + {{species.FullName}} + </p> + + <ol> + <li> + <a href="{{url_for('species.populations.list_species_populations', + species_id=species.SpeciesId)}}" + title="Create/Edit populations for {{species.FullName}}"> + Manage populations</a> + </li> + <li> + <a href="{{url_for('species.platforms.list_platforms', + species_id=species.SpeciesId)}}" + title="Create/Edit sequencing platforms for {{species.FullName}}"> + Manage sequencing platforms</a> + </li> + </ol> + + +</div> +{%endblock%} + +{%block sidebarcontents%} +<div class="card"> + <div class="card-body"> + <h5 class="card-title">Species Extras</h5> + <div class="card-text"> + <p>Some extra internal-use details (mostly for UI concerns on GeneNetwork)</p> + <p> + <small> + If you do not understand what the following are about, simply ignore them + — + They have no bearing whatsoever on your data, or its analysis. + </small> + </p> + <dl> + <dt>Family</dt> + <dd>{{species.Family}}</dd> + + <dt>FamilyOrderId</dt> + <dd>{{species.FamilyOrderId}}</dd> + + <dt>OrderId</dt> + <dd>{{species.OrderId}}</dd> + </dl> + </div> + <a href="{{url_for('species.edit_species_extra', + species_id=species.SpeciesId)}}" + class="card-link" + title="Edit the species' internal-use details.">Edit</a> + </div> +</div> +{%endblock%} diff --git a/uploader/ui.py b/uploader/ui.py new file mode 100644 index 0000000..1994056 --- /dev/null +++ b/uploader/ui.py @@ -0,0 +1,14 @@ +"""Utilities to handle the UI""" +from flask import render_template as flask_render_template + +def make_template_renderer(default): + """Render template for species.""" + def render_template(template, **kwargs): + return flask_render_template( + template, + **{ + **kwargs, + "activemenu": default, + "activelink": kwargs.get("activelink", default) + }) + return render_template diff --git a/uploader/upload/__init__.py b/uploader/upload/__init__.py deleted file mode 100644 index 5f120d4..0000000 --- a/uploader/upload/__init__.py +++ /dev/null @@ -1,7 +0,0 @@ -"""Package handling upload of files.""" -from flask import Blueprint - -from .rqtl2 import rqtl2 - -upload = Blueprint("upload", __name__) -upload.register_blueprint(rqtl2, url_prefix="/rqtl2") |