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{% extends "layout.html" %}
{% block content %}
{{ message | safe }}
<h3> <u>R</u>elationship with <u>A</u>ddiction <u>T</u>hrough <u>S</u>earches of <u>Pub</u>Med </span></a>
</h3>
<table>
<tr><td >
<p> RatsPub is a tool to efficiently and comprehensively answer the question <b>"What do we know about these genes and addiction?". </b>
<p>RatsPub answers this question by searching PubMed to find <i>sentences</i> containing the query terms (i.e., gene symbols) and <a href="https://github.com/chen42/RatsPub/blob/master/ratspub_keywords.py">over 300 drug addiction-related keywords</a> that are organized into six categories. Data from <a href="https://www.ebi.ac.uk/gwas/">NHGRI-EBI GWAS catalog </a>are also included in the search. These gene-keyword relationships are presented as an interactive graph and a table.
<p>Gene alias often include non-specific words and are thus not included in the initial search. However, a list of alias can be found by clicking on the gene symbol in the results section. These alias then can be searched with a single click.
<p>
You can create an account if you need to save your results. Up to 30 gene symbols can be entered in the box below. Gene symbols can be separated by either a space or a semicolon.
<br> <b> Example: </b><a href=http://rats.pub/progress?type=GWAS&type=addiction&type=drug&type=brain&type=stress&type=psychiatric&type=function&query=Rgma+Nrxn3+Chrna3>Rgma Nrxn3 Chrna3</a>.
<p>
<b> {%if "name" in session %}
{{session['name']}}, your previous searches are available in the <a href="/userarchive"> archive </a>.</a>
{% else %}
{% endif %}
</b>
<a>
<form action="/progress">
<div class="form-group row">
<div class="col-sm-10">
<strong>Please choose keyword categories to be included in the search:</strong>
<label>
<input type="checkbox" name="type" value="GWAS" checked> Human GWAS
<input type="checkbox" name="type" value="addiction" checked> Addiction Stage
<input type="checkbox" name="type" value="drug" checked> Drugs
<input type="checkbox" name="type" value="brain" checked> Brain Region
<input type="checkbox" name="type" value="stress" checked> Stress
<input type="checkbox" name="type" value="psychiatric" checked> Psychiatric Diseases
<input type="checkbox" name="type" value="function" checked> Function
</label>
</div>
<textarea name="query" class="form-control form-control-lg" type="search" row="3" id="searchform"></textarea>
<button type="submit" class="btn btn-primary">Search</button>
</div>
</form>
</td>
<td >
<div class='img'><img src="/static/ratspub.png" class="img-fluid">
</td>
</tr>
</table>
{% endblock %}
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