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-rw-r--r--uploader/phenotypes/views.py368
1 files changed, 368 insertions, 0 deletions
diff --git a/uploader/phenotypes/views.py b/uploader/phenotypes/views.py
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+"""Views handling ('classical') phenotypes."""
+import sys
+import uuid
+import json
+from pathlib import Path
+from functools import wraps
+
+from redis import Redis
+from requests.models import Response
+from MySQLdb.cursors import DictCursor
+from flask import (flash,
+ request,
+ url_for,
+ redirect,
+ Blueprint,
+ render_template,
+ current_app as app)
+
+# from r_qtl import r_qtl2 as rqtl2
+from r_qtl import r_qtl2_qc as rqc
+from r_qtl import exceptions as rqe
+
+from uploader import jobs
+from uploader.files import save_file#, fullpath
+from uploader.oauth2.client import oauth2_post
+from uploader.authorisation import require_login
+from uploader.db_utils import database_connection
+from uploader.species.models import all_species, species_by_id
+from uploader.monadic_requests import make_either_error_handler
+from uploader.request_checks import with_species, with_population
+from uploader.datautils import safe_int, order_by_family, enumerate_sequence
+from uploader.population.models import (populations_by_species,
+ population_by_species_and_id)
+from uploader.input_validation import (encode_errors,
+ decode_errors,
+ is_valid_representative_name)
+
+from .models import (dataset_by_id,
+ phenotype_by_id,
+ phenotypes_count,
+ save_new_dataset,
+ dataset_phenotypes,
+ datasets_by_population)
+
+phenotypesbp = Blueprint("phenotypes", __name__)
+
+@phenotypesbp.route("/phenotypes", methods=["GET"])
+@require_login
+def index():
+ """Direct entry-point for phenotypes data handling."""
+ with database_connection(app.config["SQL_URI"]) as conn:
+ if not bool(request.args.get("species_id")):
+ return render_template("phenotypes/index.html",
+ species=order_by_family(all_species(conn)),
+ activelink="phenotypes")
+
+ species = species_by_id(conn, request.args.get("species_id"))
+ if not bool(species):
+ flash("No such species!", "alert-danger")
+ return redirect(url_for("species.populations.phenotypes.index"))
+ return redirect(url_for("species.populations.phenotypes.select_population",
+ species_id=species["SpeciesId"]))
+
+
+@phenotypesbp.route("<int:species_id>/phenotypes/select-population",
+ methods=["GET"])
+@require_login
+@with_species(redirect_uri="species.populations.phenotypes.index")
+def select_population(species: dict, **kwargs):# pylint: disable=[unused-argument]
+ """Select the population for your phenotypes."""
+ with database_connection(app.config["SQL_URI"]) as conn:
+ if not bool(request.args.get("population_id")):
+ return render_template("phenotypes/select-population.html",
+ species=species,
+ populations=order_by_family(
+ populations_by_species(
+ conn, species["SpeciesId"]),
+ order_key="FamilyOrder"),
+ activelink="phenotypes")
+
+ population = population_by_species_and_id(
+ conn, species["SpeciesId"], int(request.args["population_id"]))
+ if not bool(population):
+ flash("No such population found!", "alert-danger")
+ return redirect(url_for(
+ "species.populations.phenotypes.select_population",
+ species_id=species["SpeciesId"]))
+
+ return redirect(url_for("species.populations.phenotypes.list_datasets",
+ species_id=species["SpeciesId"],
+ population_id=population["Id"]))
+
+
+
+@phenotypesbp.route(
+ "<int:species_id>/populations/<int:population_id>/phenotypes/datasets",
+ methods=["GET"])
+@require_login
+@with_population(species_redirect_uri="species.populations.phenotypes.index",
+ redirect_uri="species.populations.phenotypes.select_population")
+def list_datasets(species: dict, population: dict, **kwargs):# pylint: disable=[unused-argument]
+ """List available phenotype datasets."""
+ with database_connection(app.config["SQL_URI"]) as conn:
+ return render_template("phenotypes/list-datasets.html",
+ species=species,
+ population=population,
+ datasets=datasets_by_population(
+ conn,
+ species["SpeciesId"],
+ population["Id"]),
+ activelink="list-datasets")
+
+
+def with_dataset(
+ species_redirect_uri: str,
+ population_redirect_uri: str,
+ redirect_uri: str
+):
+ """Ensure the dataset actually exists."""
+ def __decorator__(func):
+ @wraps(func)
+ @with_population(species_redirect_uri, population_redirect_uri)
+ def __with_dataset__(**kwargs):
+ try:
+ _spcid = int(kwargs["species_id"])
+ _popid = int(kwargs["population_id"])
+ _dsetid = int(kwargs.get("dataset_id"))
+ select_dataset_uri = redirect(url_for(
+ redirect_uri, species_id=_spcid, population_id=_popid))
+ if not bool(_dsetid):
+ flash("You need to select a valid 'dataset_id' value.",
+ "alert-danger")
+ return select_dataset_uri
+ with database_connection(app.config["SQL_URI"]) as conn:
+ dataset = dataset_by_id(conn, _spcid, _popid, _dsetid)
+ if not bool(dataset):
+ flash("You must select a valid dataset.",
+ "alert-danger")
+ return select_dataset_uri
+ except ValueError as _verr:
+ app.logger.debug(
+ "Exception converting 'dataset_id' to integer: %s",
+ kwargs.get("dataset_id"),
+ exc_info=True)
+ flash("Expected 'dataset_id' value to be an integer."
+ "alert-danger")
+ return select_dataset_uri
+ return func(dataset=dataset, **kwargs)
+ return __with_dataset__
+ return __decorator__
+
+
+@phenotypesbp.route(
+ "<int:species_id>/populations/<int:population_id>/phenotypes/datasets"
+ "/<int:dataset_id>/view",
+ methods=["GET"])
+@require_login
+@with_dataset(
+ species_redirect_uri="species.populations.phenotypes.index",
+ population_redirect_uri="species.populations.phenotypes.select_population",
+ redirect_uri="species.populations.phenotypes.list_datasets")
+def view_dataset(# pylint: disable=[unused-argument]
+ species: dict, population: dict, dataset: dict, **kwargs):
+ """View a specific dataset"""
+ with database_connection(app.config["SQL_URI"]) as conn:
+ dataset = dataset_by_id(
+ conn, species["SpeciesId"], population["Id"], dataset["Id"])
+ if not bool(dataset):
+ flash("Could not find such a phenotype dataset!", "alert-danger")
+ return redirect(url_for(
+ "species.populations.phenotypes.list_datasets",
+ species_id=species["SpeciesId"],
+ population_id=population["Id"]))
+
+ start_at = max(safe_int(request.args.get("start_at") or 0), 0)
+ count = int(request.args.get("count") or 20)
+ return render_template("phenotypes/view-dataset.html",
+ species=species,
+ population=population,
+ dataset=dataset,
+ phenotype_count=phenotypes_count(
+ conn, population["Id"], dataset["Id"]),
+ phenotypes=enumerate_sequence(
+ dataset_phenotypes(conn,
+ population["Id"],
+ dataset["Id"],
+ offset=start_at,
+ limit=count),
+ start=start_at+1),
+ start_from=start_at,
+ count=count,
+ activelink="view-dataset")
+
+
+@phenotypesbp.route(
+ "<int:species_id>/populations/<int:population_id>/phenotypes/datasets"
+ "/<int:dataset_id>/phenotype/<xref_id>",
+ methods=["GET"])
+@require_login
+@with_dataset(
+ species_redirect_uri="species.populations.phenotypes.index",
+ population_redirect_uri="species.populations.phenotypes.select_population",
+ redirect_uri="species.populations.phenotypes.list_datasets")
+def view_phenotype(# pylint: disable=[unused-argument]
+ species: dict,
+ population: dict,
+ dataset: dict,
+ xref_id: int,
+ **kwargs
+):
+ """View an individual phenotype from the dataset."""
+ def __render__(privileges):
+ return render_template(
+ "phenotypes/view-phenotype.html",
+ species=species,
+ population=population,
+ dataset=dataset,
+ phenotype=phenotype_by_id(conn,
+ species["SpeciesId"],
+ population["Id"],
+ dataset["Id"],
+ xref_id),
+ privileges=(privileges
+ ### For demo! Do not commit this part
+ + ("group:resource:edit-resource",
+ "group:resource:delete-resource",)
+ ### END: For demo! Do not commit this part
+ ),
+ activelink="view-phenotype")
+
+ def __fail__(error):
+ if isinstance(error, Response) and error.json() == "No linked resource!":
+ return __render__(tuple())
+ return make_either_error_handler(
+ "There was an error fetching the roles and privileges.")(error)
+
+ with database_connection(app.config["SQL_URI"]) as conn:
+ return oauth2_post(
+ "/auth/resource/phenotypes/individual/linked-resource",
+ json={
+ "species_id": species["SpeciesId"],
+ "population_id": population["Id"],
+ "dataset_id": dataset["Id"],
+ "xref_id": xref_id
+ }
+ ).then(
+ lambda resource: tuple(
+ privilege["privilege_id"] for role in resource["roles"]
+ for privilege in role["privileges"])
+ ).then(__render__).either(__fail__, lambda resp: resp)
+
+
+@phenotypesbp.route(
+ "<int:species_id>/populations/<int:population_id>/phenotypes/datasets/create",
+ methods=["GET", "POST"])
+@require_login
+@with_population(
+ species_redirect_uri="species.populations.phenotypes.index",
+ redirect_uri="species.populations.phenotypes.select_population")
+def create_dataset(species: dict, population: dict, **kwargs):# pylint: disable=[unused-argument]
+ """Create a new phenotype dataset."""
+ with (database_connection(app.config["SQL_URI"]) as conn,
+ conn.cursor(cursorclass=DictCursor) as cursor):
+ if request.method == "GET":
+ return render_template("phenotypes/create-dataset.html",
+ activelink="create-dataset",
+ species=species,
+ population=population,
+ **decode_errors(
+ request.args.get("error_values", "")))
+
+ form = request.form
+ _errors: tuple[tuple[str, str], ...] = tuple()
+ if not is_valid_representative_name(
+ (form.get("dataset-name") or "").strip()):
+ _errors = _errors + (("dataset-name", "Invalid dataset name."),)
+
+ if not bool((form.get("dataset-fullname") or "").strip()):
+ _errors = _errors + (("dataset-fullname",
+ "You must provide a value for 'Full Name'."),)
+
+ if bool(_errors) > 0:
+ return redirect(url_for(
+ "species.populations.phenotypes.create_dataset",
+ species_id=species["SpeciesId"],
+ population_id=population["Id"],
+ error_values=encode_errors(_errors, form)))
+
+ dataset_shortname = (
+ form["dataset-shortname"] or form["dataset-name"]).strip()
+ _pheno_dataset = save_new_dataset(
+ cursor,
+ population["Id"],
+ form["dataset-name"].strip(),
+ form["dataset-fullname"].strip(),
+ dataset_shortname)
+ return redirect(url_for("species.populations.phenotypes.list_datasets",
+ species_id=species["SpeciesId"],
+ population_id=population["Id"]))
+
+
+@phenotypesbp.route(
+ "<int:species_id>/populations/<int:population_id>/phenotypes/datasets"
+ "/<int:dataset_id>/add-phenotypes",
+ methods=["GET", "POST"])
+@require_login
+@with_dataset(
+ species_redirect_uri="species.populations.phenotypes.index",
+ population_redirect_uri="species.populations.phenotypes.select_population",
+ redirect_uri="species.populations.phenotypes.list_datasets")
+def add_phenotypes(species: dict, population: dict, dataset: dict, **kwargs):# pylint: disable=[unused-argument, too-many-locals]
+ """Add one or more phenotypes to the dataset."""
+ add_phenos_uri = redirect(url_for(
+ "species.populations.phenotypes.add_phenotypes",
+ species_id=species["SpeciesId"],
+ population_id=population["Id"],
+ dataset_id=dataset["Id"]))
+ _redisuri = app.config["REDIS_URL"]
+ _sqluri = app.config["SQL_URI"]
+ with (Redis.from_url(_redisuri, decode_responses=True) as rconn,
+ # database_connection(_sqluri) as conn,
+ # conn.cursor(cursorclass=DictCursor) as cursor
+ ):
+ if request.method == "GET":
+ return render_template("phenotypes/add-phenotypes.html",
+ species=species,
+ population=population,
+ dataset=dataset,
+ activelink="add-phenotypes")
+
+ try:
+ ## Handle huge files here...
+ phenobundle = save_file(request.files["phenotypes-bundle"],
+ Path(app.config["UPLOAD_FOLDER"]))
+ rqc.validate_bundle(phenobundle)
+ except AssertionError as _aerr:
+ app.logger.debug("File upload error!", exc_info=True)
+ flash("Expected a zipped bundle of files with phenotypes' "
+ "information.",
+ "alert-danger")
+ return add_phenos_uri
+ except rqe.RQTLError as rqtlerr:
+ app.logger.debug("Bundle validation error!", exc_info=True)
+ flash("R/qtl2 Error: " + " ".join(rqtlerr.args), "alert-danger")
+ return add_phenos_uri
+
+ _jobid = uuid.uuid4()
+ _namespace = jobs.jobsnamespace()
+ _ttl_seconds = app.config["JOBS_TTL_SECONDS"]
+ _job = jobs.initialise_job(
+ rconn,
+ _namespace,
+ str(_jobid),
+ [sys.executable, "-m", "scripts.rqtl2.phenotypes_qc", _sqluri,
+ _redisuri, _namespace, str(_jobid), str(species["SpeciesId"]),
+ str(population["Id"]), str(dataset["Id"]), "--redisexpiry",
+ str(_ttl_seconds)], "phenotype_qc", _ttl_seconds,
+ {"job-metadata": json.dumps({
+ "speciesid": species["SpeciesId"],
+ "populationid": population["Id"],
+ "datasetid": dataset["Id"],
+ "bundle": str(phenobundle.absolute())})})
+ # jobs.launch_job(
+ # _job,
+ # redisuri,
+ # f"{app.config['UPLOAD_FOLDER']}/job_errors")
+
+ raise NotImplementedError("Please implement this...")