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-rwxr-xr-xratspub.py10
-rw-r--r--ratspub_keywords.py12
-rwxr-xr-xserver.py30
3 files changed, 41 insertions, 11 deletions
diff --git a/ratspub.py b/ratspub.py
index 8ee1f74..7320889 100755
--- a/ratspub.py
+++ b/ratspub.py
@@ -6,7 +6,6 @@ from ratspub_keywords import *
global function_d, brain_d, drug_d, addiction_d, brain_query_term, pubmed_path
-
## turn dictionary (synonyms) to regular expression
def undic(dic):
return "|".join(dic.values())
@@ -103,14 +102,15 @@ function=undic(function_d)
addiction=undic(addiction_d)
drug=undic(drug_d)
-nodecolor={'function':"#A9CCE3", 'addiction': "#D7BDE2", 'drug': "#F9E79F", 'brain':"#A3E4D7", 'gwas':"#AEB6BF"}
-#https://htmlcolorcodes.com/
+nodecolor={'function':"#A9CCE3", 'addiction': "#D7BDE2", 'drug': "#F9E79F", 'brain':"#A3E4D7", 'gwas':"#AEB6BF", 'stress':"#EDBB99", 'psychiatric':"#F5B7B1"}
+#https://htmlcolorcodes.com/ third column down
n0=generate_nodes(function_d, 'function')
n1=generate_nodes(addiction_d, 'addiction')
n2=generate_nodes(drug_d, 'drug')
n3=generate_nodes(brain_d, 'brain')
-default_nodes=n0+n1+n2+n3
-
+n4=generate_nodes(stress_d, 'stress')
+n5=generate_nodes(psychiatric_d, 'psychiatric')
+default_nodes=n0+n1+n2+n3+n4+n5
host= os.popen('hostname').read().strip()
if host=="x1":
diff --git a/ratspub_keywords.py b/ratspub_keywords.py
index 8a23e73..ade04f6 100644
--- a/ratspub_keywords.py
+++ b/ratspub_keywords.py
@@ -31,3 +31,15 @@ function_d={"signalling":"signalling|signaling|phosphorylation|glycosylation",
"neurotransmission": "neurotransmission|neuropeptides|neuropeptide|glutamate|glutamatergic|GABA|GABAergic|dopamine|dopaminergic|DAergic|cholinergic|nicotinic|muscarinic|serotonergic|serotonin|5 ht|acetylcholine",
}
#"regulation":"increased|decreased|regulated|inhibited|stimulated",
+
+stress_d={"stress":"stress|psycological trauma|distress",
+ "PTSD":"PTSD"
+ }
+psychiatric_d={"anxiety":"anxiety|anxious",
+ "depression":"depression|depressive",
+ "bipolar":"bipolar disorder",
+ "impulsivity":"impulsivity|impulsive",
+ "compulsive":"compulsive|obssessive",
+ "schizophrenia": "schizophrenia",
+ "autism": "autism|autistic"
+ }
diff --git a/server.py b/server.py
index d312a5a..07e5f72 100755
--- a/server.py
+++ b/server.py
@@ -20,7 +20,7 @@ def about():
@app.route('/progress')
def progress():
- # only 1-6 terms are allowed
+ # only 1-100 terms are allowed
genes=request.args.get('query')
genes=genes.replace(",", " ")
genes=genes.replace(";", " ")
@@ -42,7 +42,7 @@ def progress():
@app.route("/search")
def search():
genes=session['query']
- percent=round(100/(len(genes)*4),1)
+ percent=round(100/(len(genes)*6),1) # 6 categories
snt_file=session['path']+"_snt"
cysdata=open(session['path']+"_cy","w+")
sntdata=open(snt_file,"w+")
@@ -79,16 +79,34 @@ def search():
sent3=gene_category(gene, brain_d, brain_query_term, "brain")
progress+=percent
e3=generate_edges(sent3, tf_name)
+ # stress
+ stress=undic(stress_d)
+ sent4=gene_category(gene, stress_d, stress, "drug")
+ progress+=percent
+ yield "data:"+str(progress)+"\n\n"
+ e4=generate_edges(sent4, tf_name)
+ # psychiatric
+ psychiatric=undic(psychiatric_d)
+ sent5=gene_category(gene, psychiatric_d, psychiatric, "psychiatric")
+ progress+=percent
+ yield "data:"+str(progress)+"\n\n"
+ e5=generate_edges(sent5, tf_name)
# gwas
- e4=searchArchived('gwas', gene)
- geneEdges=e0+e1+e2+e3+e4
+ e6=searchArchived('gwas', gene)
+ geneEdges=e0+e1+e2+e3+e4+e5+e6
## there is a bug here. zero link notes are not excluded anymore
if len(geneEdges) >1:
edges+=geneEdges
nodes+="{ data: { id: '" + gene + "', nodecolor:'#E74C3C', fontweight:700, url:'/startGeneGene?forTopGene="+gene+"'} },\n"
else:
nodesToHide+=gene + " "
- sentences+=sent0+sent1+sent2+sent3
+ sentences+=sent0+sent1+sent2+sent3+sent4+sent5
+ sent0=None
+ sent1=None
+ sent2=None
+ sent3=None
+ sent4=None
+ sent5=None
#save data before the last yield
searchCnt+=1
if (searchCnt==len(genes)):
@@ -138,7 +156,7 @@ def showTopGene():
@app.route("/shownode")
def shownode():
node=request.args.get('node')
- allnodes={**brain_d, **drug_d, **function_d, **addiction_d}
+ allnodes={**brain_d, **drug_d, **function_d, **addiction_d, **stress_d, **psychiatric_d}
out="<p>"+node.upper()+"<hr><li>"+ allnodes[node].replace("|", "<li>")
return render_template('sentences.html', sentences=out+"<p>")