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author | root | 2012-05-08 18:39:56 -0500 |
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committer | root | 2012-05-08 18:39:56 -0500 |
commit | ea46f42ee640928b92947bfb204c41a482d80937 (patch) | |
tree | 9b27a4eb852d12539b543c3efee9d2a47ef470f3 /web/tutorial/ppt/html/webqtl_demo2.ppt_files/slide0054.htm | |
parent | 056b5253fc3857b0444382aa39944f6344dc1ceb (diff) | |
download | genenetwork2-ea46f42ee640928b92947bfb204c41a482d80937.tar.gz |
Add all the source codes into the github.
Diffstat (limited to 'web/tutorial/ppt/html/webqtl_demo2.ppt_files/slide0054.htm')
-rwxr-xr-x | web/tutorial/ppt/html/webqtl_demo2.ppt_files/slide0054.htm | 113 |
1 files changed, 113 insertions, 0 deletions
diff --git a/web/tutorial/ppt/html/webqtl_demo2.ppt_files/slide0054.htm b/web/tutorial/ppt/html/webqtl_demo2.ppt_files/slide0054.htm new file mode 100755 index 00000000..64dbe68f --- /dev/null +++ b/web/tutorial/ppt/html/webqtl_demo2.ppt_files/slide0054.htm @@ -0,0 +1,113 @@ +<html>
<head>
<meta name=ProgId content=PowerPoint.Slide>
<meta name=Generator content="Microsoft Macintosh PowerPoint 11">
<title>PowerPoint Presentation - Complex trait analysis, develop-ment, and
genomics</title>
<link title="Presentation File" type="application/powerpoint" rel=alternate
href="webqtl_demo2.ppt.ppt">
<script> +if ( ! top.PPTPRESENTATION ) { + window.location.replace( "endshow.htm" ); +} +</script>
<meta name=Description
content="Jul-18-05: Genetic versus Physical maps for App expression">
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mso-text-indent-alt:0;mso-line-spacing:"-358 0 -1";mso-margin-left-alt:233;
mso-text-indent-alt:0'><span style='font-family:Verdana;font-size:64%'><i>Genetic
versus Physical maps for App expression</i></span><span style='font-family:
Verdana;font-size:73%;mso-special-format:lastCR;display:none'><i><br>
</i></span></div>
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style='text-align:left'><span style='font-size:117%;color:#E9EB5D'><i>The
difference between genetic and physical scale is analogous to measuring the </i></span></span></layer><script> + mytop = 0.03 * g_height; myleft = 0 * g_width; myheight = 0.04 * g_height; mywidth = 0.92 * g_width; + document.write( '<layer top=' + mytop + ' left=' + myleft + ' height=' + myheight + ' width=' + mywidth + ' >' ); +</script><span
style='text-align:left'><span style='font-size:117%;color:#E9EB5D'><i>separation
between New York and Boston in either travel hours or kilometers</i></span><span
style='font-size:150%;color:#E9EB5D'><i>.</i></span><span style='font-size:
167%;color:#E9EB5D;mso-special-format:lastCR;display:none'><i><br>
</i></span></span></layer></div>
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+
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<div id=NotesObj style='display:none'>
<table style='color:white' border=0 width="100%">
<tr>
<td width=5 nowrap></td>
<td width="100%"></td>
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<tr>
<td colspan=1></td>
<td align=left colspan=1><font face=Verdana size=3>The map on the top has an
X-axis scale based on frequency of recombinations events between markers (B
to D transitions, see slide 19 for a color-coded example). These so-called
genetic maps are scaled in centimorgan (recombinations per 100 gametes). In
contrast, the physical map shown below the genetic map has an X-axis scale
based on DNA length measured in nucleotides or base-pairs. Notice the large
difference between the two maps in the size of Chr 19 (large on the genetic
scale but small on the physical scale).</font><br>
</td>
</tr>
<tr>
<td colspan=1></td>
<td align=left colspan=1><font face=Verdana size=3>Also notice the large
difference in the width of the chromosome 7 QTL peak. In mice,
recombinations occur with higher frequency toward the telomeric side (righ
sidet) of each chromosome. As a result, genetic maps are stretched out more
toward the telomere relative to a physical map. The QTL on distal Chr 7 is
therefore actually more precisely mapped than might appear looking at the
genetic map.</font><br>
</td>
</tr>
<tr>
<td colspan=1></td>
<td align=left colspan=1><font face=Verdana size=3>The physical scale is
becoming more useful than the genetic scale primarily because many other
data types can be easily superimposed on a physical map. You will see more
examples in the next several slides.</font><br>
</td>
</tr>
</table>
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