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{% extends "layout.html" %}
{% block content %}
{{ message | safe }}

<h3> <u>R</u>elationship with <u>A</u>ddiction <u>T</u>hrough <u>S</u>earches of <u>Pub</u>Med </span></a>
</h3>

<table>
	<tr><td >

<p> RatsPub searches PubMed to find <i>sentences</i> that contain the query terms (i.e., gene symbols) and <a href="https://github.com/chen42/RatsPub/blob/master/ratspub_keywords.py">drug addiction-related keywords</a>. These gene-keyword relationships are presented as an interactive graph that can efficiently answer the question <b>"What do we know about these genes and addiction?". </b> Data from <a href="https://www.ebi.ac.uk/gwas/">EBI GWAS catalog </a>are also included in the search.  The graph has many interactive elements. For example, clicking gene names will launch a new search for sentences containing the target gene and 200 addiction-related genes. A tabular view is also available. </b>

		<p>Up to 100 gene symbols can be entered in the box below. Gene symbols can be separated by either a space or a semicolon. Aliases will <i>not</i> be automatically included because the large number of false matches associated with gene synonyms retrieved from databases. 

	<b>	{%if "name" in session %}
		{{session['name']}}, your previous searches are <a href="/userarchive">archived </a> for faster retrival.</a>
	{% else %}
		Please sign in to save your searches.
	{% endif %}
	</b>


		</td>
		<td >
			<div class='img'><img src="/static/ratspub.png" class="img-fluid">
		</td>
	</tr>
</table>

	<a>

<b> Example: </b>Rgma Nrxn3 Chrna3 <p> 

	<form action="/progress">
	<div class="form-group row">
		<div class="col-sm-10">
	<strong>Please choose keyword categories to be included in the search:</strong>
			<label>
			<input type="checkbox" name="type" value="GWAS" checked> Human GWAS 	
			<input type="checkbox" name="type" value="addiction" checked> Addiction Stage 				
			<input type="checkbox" name="type" value="drug" checked> Drugs		
			<input type="checkbox" name="type" value="brain" checked> Brain region				
			<input type="checkbox" name="type" value="stress" checked> Stress				
			<input type="checkbox" name="type" value="psychiatric" checked> Psychiatric Diseases
			<input type="checkbox" name="type" value="function" checked> Function				
			</label>
		</div>

 
	<textarea name="query" class="form-control form-control-lg" type="search" row="3" id="searchform">
	</textarea>
 <button type="submit" class="btn btn-primary">Search</button>
 </div>
	</form>


{% endblock %}