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{'brain': {'accumbens': {'acbc|acbs|accumbal|accumbens|core|Nacc|NacSh|shell'}, 'amygdala': {'amy|amygdala|bla|cea|cna'}, 'cortex': {'cerebral|cingulate|cortex|cortico limbic|corticolimbic|corticostriatal|infralimbic|insular|mPFC|orbitofrontal|pfc|prefrontal|prelimbic|prl|vmpfc'}, 'habenula': {'habenula|lhb|mhb'}, 'hippocampus': {'ca1|ca3|dentate gyrus|dhpc|hip|hipp|hippocampal|hippocampus|subiculum|vhipp|vhpc'}, 'hypothalamus': {'hypothalamic|hypothalamus|LHA|paraventricular nucleus|PVN'}, 'striatum': {'basal ganglia|caudate|globus pallidus|GPI|putamen|STR|striatal|striatum'}, 'VTA': {'limbic|mesoaccumbal|mesoaccumbens|mesolimbic|midbrain|pvta|ventral tegmental|vta'}},
'addiction': {'addiction': {'addiction|addictive|compulsive|drug abuse|escalation|punishment'}, 'aversion': {'aversion|aversive|conditioned taste aversion|CTA'}, 'dependence': {'dependence'}, 'intoxication': {'binge|intoxication'}, 'relapse': {'craving|drug seeking|reinstatement|relapse|seeking'}, 'reward': {'conditioned place preference|CPP|drug reinforced|hedonic|ICSS|incentive|instrumental response|intracranial self stimulation|operant|reinforcement|reinforcing|reward|self administered|self administration'}, 'sensitization': {'behavioral sensitization|locomotor sensitization|drug sensitization|incentive sensitization'}, 'social': {'social'}, 'withdrawal': {'withdrawal'}},
'drug': {'alcohol': {'acamprosate|alcohol|alcoholics|alcoholism|antabuse|campral|disulfiram|ethanol|naltrexone|revia|vivitrol'}, 'amphetamine': {'AMPH|amphetamine|METH|methamphetamine'}, 'benzodiazepine': {'adinazolam|alprazolam|benzodiazepine|benzos|brotizolam|chlordiazepoxide|climazolam|clobazam|clonazepam|clorazepate|diazepam|estazolam|flunitrazepam|flurazepam|halazepam|librium|loprazolam|lorazepam|lormetazepam|midazolam|nimetazepam|nitrazepam|normison|oxazepam|prazepam|temazepam|triazolam|valium|xanax'}, 'cannabinoid': {'acylethanolamines|cannabichromene|cannabidiol|cannabigerol|cannabinoids|cannabinol|cannabis|cannabivarin|cesamet|drobinal|dronabinol|endocannabinoids|epidiolex|JWH 018|JWH 122|JWH 250|marijuana|marinol|nabilone|Oleoylethanolamide|palmitoylethanolamide|phytocannabinoid|rimonabant|SR141716|SR144528|syndros|tetrahydrocannabinol|tetrahydrocannabivarin|thc|thc 9'}, 'cocaine': {'cocaine'}, 'nicotine': {'nicotine|smokers|smoking|tobacco'}, 'opioid': {'buprenorphine|codeine|fentanyl|heroin|hycodan|hydrocodone|hydromorphone|kadian|kratom|methadone|morphine|naloxone|opioids|oxycodone|oxycontin|percocet|suboxone|tramadol|ultram|vicodin'}, 'psychedelics': {'ayahuasca|ecstasy|ibogaine|ketamine|LSD|lysergic acid diethylamide|MDMA|mescaline|methylenedioxymethamphetamine|N methoxybenzyl|NBOMes|peyote|psilocybin|psychedelic|psychedelics'}},
'function': {'neuroplasticity': {'boutons|epsc|epsp|IPSC|IPSP|long term depression|long term potentiation|LTD|LTP|mIPSC|neurite|neurogenesis|neuroplasticity|plasticity|synaptic'}, 'neurotransmission': {'5 ht|acetylcholine|cholinergic|DAergic|dopamine|dopaminergic|GABA|GABAergic|glutamate|glutamatergic|muscarinic|neuropeptides|neurotransmission|nicotinic|serotonergic|serotonin'}, 'signalling': {'glycosylation|phosphorylation|signaling|signalling|kinase|binding|signal transduction|second messengers|cGMP|cAMP'}, 'transcription': {'histone|hypermethylation|hypomethylation|methylation|ribosome|transcription'}},
'psychiatric': {'anxiety': {'anxiety|anxious'}, 'autism': {'autism|autistic'}, 'bipolar': {'bipolar disorder'}, 'compulsive': {'compulsive|obsessive'}, 'depression': {'depression|depressive|major depressive disorder|MDD'}, 'impulsivity': {'5 CSRTT|5 choice task|delay discounting|delay exposure|delay intolerance|delayed reward|delay task|five choice serial reaction time task|impulsive|impulsivity|premature responding'}, 'schizophrenia': {'schizophrenia'}},
'cell': {'neuron': {'adrenergic neurons|cholinergic neurons|dopaminergic neurons|gabaergic neurons|glutamatergic neurons|GnRH neurons|interneurons|monoaminergic neurons|medium spiny neurons|motor neurons|neuronal cells|nitrergic neurons|noradrenergic neurons|projection neurons|pyramidal neurons|sensory neurons|serotonergic neurons|somatostatin neurons|neurons|excitatory neurons|inhibitory neurons|corticospinal neurons|dopamine neurons|D1 neurons|D2 neurons|afferent neurons|efferent neurons|serotonin neurons|cortical neurons|hippocampal neurons|DA neurons|CNS neurons|cortex neurons|mesencephalic neurons|orexin neurons|catecholaminergic neurons|striatal neurons|bipolar neurons|ganglion cells|RGC|horizontal cells|amacrine cells'}, 'astrocyte': {'astrocytic|astrocytes|astroglia|astroglial'}, 'microglia': {'microglia|microglial'}, 'endothelium': {'endothelium|endothelial cells'}, 'oligodendrocyte': {'oligodendrocytes'}},
'stress': {'PTSD': {'PTSD|post traumatic stress|post traumatic stress symptoms|post traumatic stress disorder'}, 'stress': {'distress|psychological trauma|stress'}},
'GWAS': {'psychiatric': {'psychiatric|schizophrenia|autism|depression|anxiety|bipolar|mental'},'nicotine': {'nicotine|smoking|chronic obstructive|tobacco'}, 'addiction': {'addiction|cocaine|opioid|morphine|amphetamine|methadone|heroin|drug dependence'}, 'alcohol': {'alcohol'}}}
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