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diff --git a/ratspub_keywords.py b/ratspub_keywords.py
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+addiction_d = {"reward":"reward|hedonic|incentive|intracranial self stimulation|ICSS|reinforcement|reinforcing|conditioned place preference|CPP|self administration|self administered|drug reinforced|operant|instrumental response",
+        "aversion":"aversion|aversive|CTA|conditioned taste aversion",
+        "withdrawal":"withdrawal",
+        "relapse":"relapse|reinstatement|craving|drug seeking|seeking",
+        "sensitization":"sensitization",
+        "addiction":"addiction|addictive|drug abuse|punishment|compulsive|escalation",
+        "dependence":"dependence",
+        "intoxication":"intoxication|binge"
+        }
+drug_d = {"alcohol":"alcohol|alcoholism|alcoholic|alcoholics",
+        "nicotine":"smoking|nicotine|tobacco|smoker|smokers",
+        "cocaine":"cocaine",
+        "opioid":"opioid|opioids|fentanyl|oxycodone|oxycontin|heroin|morphine|methadone|buprenorphine|vicodin|hydrocodone|hycodan|kadian|percoset|hydromorphone|naloxone|codeine|suboxone|tramadol|kratom|ultram",
+        "amphetamine":"methamphetamine|amphetamine|METH|AMPH",
+        "cannabinoid":"endocannabinoid|cannabinoids|cannabis|endocannabinoids|marijuana|cannabidiol|cannabinoid|tetrahydrocannabinol|thc|thc 9|Oleoylethanolamide|palmitoylethanolamide|acylethanolamides"
+        }
+brain_d ={"cortex":"cortex|prefrontal|pfc|mPFC|vmpfc|corticostriatal|cortico limbic|corticolimbic|prl|prelimbic|infralimbic|orbitofrontal|cingulate|cerebral|insular|insula",
+          "striatum":"striatum|STR|striatal|caudate|putamen|basal ganglia|globus pallidus|GPI",
+          "accumbens":"accumbens|accumbal|shell|core|Nacc|NacSh|acbs|acbc",
+          "hippocampus":"hippocampus|hippocampal|hipp|hip|ca1|ca3|dentate gyrus|subiculum|vhipp|dhpc|vhpc",
+          "amygdala":"amygdala|cea|bla|amy|cna",
+          "VTA":"ventral tegmental|vta|pvta|mesolimbic|limbic|midbrain|mesoaccumbens|mesoaccumbal",
+          "habenula":"habenula|lhb|mhb",
+          "hypothalamus":"hypothalamus|hypothalamic|PVN|paraventricular nucleus"
+          }
+# brain region has too many short acronyms to just use the undic function, so search PubMed using the following 
+brain_query_term="cortex|accumbens|striatum|amygadala|hippocampus|tegmental|mesolimbic|infralimbic|prelimbic|habenula"
+function_d={"signalling":"signalling|signaling|phosphorylation|glycosylation",
+            "transcription":"transcription|methylation|hypomethylation|hypermethylation|histone|ribosome",
+            "neuroplasticity":"neuroplasticity|plasticity|long term potentiation|LTP|long term depression|LTD|synaptic|epsp|epsc|neurite|neurogenesis|boutons|mIPSC|IPSC|IPSP",
+            "neurotransmission": "neurotransmission|neuropeptides|neuropeptide|glutamate|glutamatergic|GABA|GABAergic|dopamine|dopaminergic|DAergic|cholinergic|nicotinic|muscarinic|serotonergic|serotonin|5 ht|acetylcholine",
+            }
+#"regulation":"increased|decreased|regulated|inhibited|stimulated",