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Diffstat (limited to 'get_addiction_sentences.py')
-rw-r--r-- | get_addiction_sentences.py | 83 |
1 files changed, 0 insertions, 83 deletions
diff --git a/get_addiction_sentences.py b/get_addiction_sentences.py deleted file mode 100644 index 30a8e50..0000000 --- a/get_addiction_sentences.py +++ /dev/null @@ -1,83 +0,0 @@ -#!/bin/env python3 -from nltk.tokenize import sent_tokenize -import os -import re -import codecs -import sys - -gene=sys.argv[1] - -addiction_terms="sensitization|intake|addiction|drug abuse|relapse|self-administered|self-administration|voluntary|reinstatement|binge|intoxication|withdrawal|chronic" - -drugs="alcohol|alcoholism|smoking|nicotine|tobacco|methamphetamine|amphetamine|cocaine|opioid|fentanyl|oxycodone|oxycontin|heroin|morphine|marijuana|cannabinoid|tetrahydrocannabinol|thc" - -brain_regions="cortex|accumbens|striatum|amygadala|hippocampus|tegmental|mesolimbic|infralimbic|prelimbic" - -brain_d ={"cortex":"cortex|pfc|vmpfc|il|pl|prelimbic|infralimbic", - "striatum":"striatum|STR", - "accumbens":"shell|core|NAcc|acbs|acbc", - "hippocampus":"hippocampus|hipp|hip|ca1|ca3|dentate|gyrus", - "amygadala":"amygadala|cea|bla|amy", - "ventral tegmental":"ventral tegmental|vta" - } - -function="LTP|LTD|plasticity|regulate|glutamate|GABA|cholinergic|serotoninergic|synaptic|methylation|transcription|phosphorylation" - -drugs_d = {"alcohol":"alcohol|alcoholism", - "nicotine":"smoking|nicotine|tobacco", - "amphetamine":"methamphetamine|amphetamine", - "cocaine":"cocaine", - "opioid":"opioid|fentanyl|oxycodone|oxycontin|heroin|morphine", - "cannabinoid":"marijuana|cannabinoid|Tetrahydrocannabinol|thc" - } - -def findWholeWord(w): - return re.compile(r'\b({0})\b'.format(w), flags=re.IGNORECASE).search - -def getSentences(query): - abstracts = os.popen("esearch -db pubmed -query " + query + " | efetch -format uid |fetch-pubmed -path /run/media/hao/PubMed/Archive/ | xtract -pattern PubmedArticle -element MedlineCitation/PMID,ArticleTitle,AbstractText").read() - out=str() - for row in abstracts.split("\n"): - tiab=row.split("\t") - pmid = tiab.pop(0) - tiab= " ".join(tiab) - sentences = sent_tokenize(tiab) - for sent in sentences: - if findWholeWord(gene)(sent): - sent=re.sub(r'\b(%s)\b' % gene, r'<b>\1</b>', sent, flags=re.I) - out+=pmid+"\t"+sent+"\n" - return(out) - -def gene_addiction(gene): - q="\"(" + addiction_terms.replace("|", " OR ") + ") AND (" + drugs.replace("|", " OR ", ) + ") AND " + gene + "\"" - sents=getSentences(q) - out=str() - for sent in sents.split("\n"): - for drug0 in drugs_d: - if findWholeWord(drugs_d[drug0])(sent) : - sent=re.sub(r'\b(%s)\b' % drugs_d[drug0], r'<b>\1</b>', sent, flags=re.I) - out+=gene+"\t"+drug0+"\t"+sent+"\n" - return(out) - -def gene_brainRegion(gene): - q="\"(" + brain_regions.replace("|", " OR ") + ") AND " + gene + "\"" - sents=getSentences(q) - out=str() - for sent in sents.split("\n"): - for brain0 in brain_d: - if findWholeWord(brain_d[brain0])(sent) : - sent=re.sub(r'\b(%s)\b' % brain_d[brain0], r'<b>\1</b>', sent, flags=re.I) - out+=gene+"\t"+brain0+"\t"+sent+"\n" - return(out) - -report=str() -out=gene_addiction(gene) -report+=out -out=gene_brainRegion(gene) -report+=out -with codecs.open(gene+"_addiction_sentences.tab", "w", encoding='utf8') as writer: - writer.write(report) - writer.close() - - - |