about summary refs log tree commit diff
path: root/examples/strains.scm
blob: cb4978fa713a59dcb653d37946643c95d8297d80 (plain)
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
#! /usr/bin/env guile
!#

(use-modules (srfi srfi-1)
             (srfi srfi-26)
             (ice-9 getopt-long)
             (ice-9 match)
             (ice-9 regex)
             (transform strings)
             (transform sql)
             (transform triples)
             (transform special-forms))


#!

The ProbeData table contains StrainID.

MariaDB [db_webqtl]> select * from ProbeData limit 2;
+--------+----------+---------+
| Id     | StrainId | value   |
+--------+----------+---------+
| 503636 |       42 | 11.6906 |
| 503636 |       43 | 11.4205 |
+--------+----------+---------+

Likewise

MariaDB [db_webqtl]> select * from ProbeSetData wher limit 2;
+----+----------+-------+
| Id | StrainId | value |
+----+----------+-------+
|  1 |        1 | 5.742 |
|  1 |        2 | 5.006 |
+----+----------+-------+

To get at the strain use

MariaDB [db_webqtl]> select * from Strain where Id=1 limit 15;
+----+--------+--------+-----------+--------+-------+
| Id | Name   | Name2  | SpeciesId | Symbol | Alias |
+----+--------+--------+-----------+--------+-------+
|  1 | B6D2F1 | B6D2F1 |         1 | NULL   | NULL  |
+----+--------+--------+-----------+--------+-------+

A typical query may look like

SELECT Strain.Name, Strain.Id FROM Strain, Species
WHERE Strain.Name IN f{create_in_clause(self.samplelist)}
AND Strain.SpeciesId=Species.Id
AND Species.name = %s, (self.group.species,)

At this point it is not very clear how Name, Name2, Symbol and Alias are used.

!#

(define-transformer strain
  (tables (Strain
           (left-join Species "ON Strain.SpeciesId = Species.SpeciesId")))
  (schema-triples
   (gnt:alias rdfs:domain gnc:strain)
   (gnt:alias a owl:ObjectProperty)
   (gnt:gene_symbol rdfs:domain gnc:strain)
   (gnt:gene_symbol a owl:ObjectProperty))
  (triples (string->identifier
            "strain"
            (field Strain Name)
            #:separator "_")
    (set rdf:type 'gnc:strain)
    (set gnt:belongs_to_species (string->identifier "" (remap-species-identifiers (field Species Fullname))))
    ;; Name, and maybe a second name
    (set rdfs:label (sanitize-rdf-string (field Strain Name)))
    (set skos:altLabel (sanitize-rdf-string (field ("IF ((Strain.Name2 != Strain.Name), Strain.Name2, '')" Name2))))
    (set gnt:alias (sanitize-rdf-string (field ("IF ((Strain.Alias != Strain.Name), Strain.Alias, '')" Alias))))
    (set gnt:gene_symbol (field Strain Symbol))))

(define-transformer mapping-method
  (tables (MappingMethod))
  (schema-triples
   (gnc:mapping_method a skos:Concept)
   (gnc:mapping_method skos:definition "Terms that decribe mapping methods used on this resource"))
  (triples
      (string->identifier "mapping_method" (field MappingMethod Name) #:separator "_")
    (set rdf:type 'gnc:mapping_method)
    (set rdfs:label (field MappingMethod Name))))

(define-transformer avg-method
  ;; The Name and Normalization fields seem to be the same. Dump only
  ;; the Name field.
  (tables (AvgMethod))
  (schema-triples
   (gnc:avg_method a skos:Concept)
   (gnc:avg_method skos:definition "Terms that decribe normalization methods used on this resource"))
  (triples (string->identifier "avg_method" (field AvgMethod Name AvgMethodName) #:separator "_")
    (set rdf:type 'gnc:avg_method)
    (set rdfs:label (field AvgMethod Normalization))))



(let* ((option-spec
        '((settings (single-char #\s) (value #t))
          (output (single-char #\o) (value #t))
          (documentation (single-char #\d) (value #t))))
       (options (getopt-long (command-line) option-spec))
       (settings (option-ref options 'settings #f))
       (output (option-ref options 'output #f))
       (documentation (option-ref options 'documentation #f))
       (%connection-settings
        (call-with-input-file settings
          read)))

  (with-documentation
   (name "Strain Metadata")
   (connection %connection-settings)
   (table-metadata? #f)
   (prefixes
    '(("gn:" "<http://rdf.genenetwork.org/v1/id/>")
      ("gnc:" "<http://rdf.genenetwork.org/v1/category/>")
      ("owl:" "<http://www.w3.org/2002/07/owl#>")
      ("gnt:" "<http://rdf.genenetwork.org/v1/term/>")
      ("skos:" "<http://www.w3.org/2004/02/skos/core#>")
      ("xkos:" "<http://rdf-vocabulary.ddialliance.org/xkos#>")
      ("rdf:" "<http://www.w3.org/1999/02/22-rdf-syntax-ns#>")
      ("rdfs:" "<http://www.w3.org/2000/01/rdf-schema#>")
      ("taxon:" "<http://purl.uniprot.org/taxonomy/>")))
   (inputs
    (list strain mapping-method avg-method))
   (outputs
    `(#:documentation ,documentation
      #:rdf ,output))))