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authorMunyoki Kilyungi2023-08-25 18:17:56 +0300
committerMunyoki Kilyungi2023-08-28 12:38:35 +0300
commitd3e1a1191ced13d00a2e24b286998630f14abae6 (patch)
tree0dcc8af64ae35a659d2cf372e853df9993279490 /examples/strains.scm
parentc9a84ecb21c7fcfdb9e5d277bd2a1c43b73f4f9f (diff)
downloadgn-transform-databases-d3e1a1191ced13d00a2e24b286998630f14abae6.tar.gz
Rename file
Signed-off-by: Munyoki Kilyungi <me@bonfacemunyoki.com>
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+#! /usr/bin/env guile
+!#
+
+(use-modules (srfi srfi-1)
+ (srfi srfi-26)
+ (ice-9 getopt-long)
+ (ice-9 match)
+ (ice-9 regex)
+ (transform strings)
+ (transform sql)
+ (transform triples)
+ (transform special-forms))
+
+(define (remap-species-identifiers str)
+ "This procedure remaps identifiers to standard binominal. Obviously this should
+ be sorted by correcting the database!"
+ (match str
+ ["Fly (Drosophila melanogaster dm6)" "Drosophila melanogaster"]
+ ["Oryzias latipes (Japanese medaka)" "Oryzias latipes"]
+ ["Macaca mulatta" "Macaca nemestrina"]
+ ["Bat (Glossophaga soricina)" "Glossophaga soricina"]
+ [str str]))
+
+#!
+
+The ProbeData table contains StrainID.
+
+MariaDB [db_webqtl]> select * from ProbeData limit 2;
++--------+----------+---------+
+| Id | StrainId | value |
++--------+----------+---------+
+| 503636 | 42 | 11.6906 |
+| 503636 | 43 | 11.4205 |
++--------+----------+---------+
+
+Likewise
+
+MariaDB [db_webqtl]> select * from ProbeSetData wher limit 2;
++----+----------+-------+
+| Id | StrainId | value |
++----+----------+-------+
+| 1 | 1 | 5.742 |
+| 1 | 2 | 5.006 |
++----+----------+-------+
+
+To get at the strain use
+
+MariaDB [db_webqtl]> select * from Strain where Id=1 limit 15;
++----+--------+--------+-----------+--------+-------+
+| Id | Name | Name2 | SpeciesId | Symbol | Alias |
++----+--------+--------+-----------+--------+-------+
+| 1 | B6D2F1 | B6D2F1 | 1 | NULL | NULL |
++----+--------+--------+-----------+--------+-------+
+
+A typical query may look like
+
+SELECT Strain.Name, Strain.Id FROM Strain, Species
+WHERE Strain.Name IN f{create_in_clause(self.samplelist)}
+AND Strain.SpeciesId=Species.Id
+AND Species.name = %s, (self.group.species,)
+
+At this point it is not very clear how Name, Name2, Symbol and Alias are used.
+
+!#
+
+(define-transformer strain
+ (tables (Strain
+ (left-join Species "ON Strain.SpeciesId = Species.SpeciesId")))
+ (schema-triples
+ (gnc:strain skos:broader gnc:species)
+ (gnt:belongsToSpecies rdfs:domain gnc:strain)
+ (gnt:belongsToSpecies skos:definition "This resource belongs to this species")
+ (gnt:belongsToSpecies a owl:ObjectProperty)
+ (gnt:belongsToSpecies skos:definition "This resource belongs to this species")
+ (gnt:alias rdfs:domain gnc:strain)
+ (gnt:alias a owl:ObjectProperty)
+ (gnt:symbol rdfs:domain gnc:strain)
+ (gnt:symbol a owl:ObjectProperty))
+ (triples (string->identifier
+ ""
+ (regexp-substitute/global
+ #f "[^A-Za-z0-9:]"
+ (field Strain Name)
+ 'pre "_" 'post)
+ #:separator ""
+ #:proc string-capitalize-first)
+ (set rdf:type 'gnc:strain)
+ (set gnt:belongsToSpecies
+ (string->identifier "" (remap-species-identifiers (field Species Fullname))
+ #:separator ""
+ #:proc string-capitalize-first))
+ ;; Name, and maybe a second name
+ (set rdfs:label (sanitize-rdf-string (field Strain Name)))
+ (set rdfs:label (sanitize-rdf-string (field ("IF ((Strain.Name2 != Strain.Name), Strain.Name2, '')" Name2))))
+ (set gnt:alias (sanitize-rdf-string (field ("IF ((Strain.Alias != Strain.Name), Strain.Alias, '')" Alias))))
+ (set gnt:symbol (field ("IF ((Strain.Symbol != Strain.Name), Strain.Symbol, '')" Symbol)))))
+
+(define-transformer mapping-method
+ (tables (MappingMethod))
+ (schema-triples
+ (gnc:mappingMethod a skos:Concept)
+ (gnc:mappingMethod skos:definition "Terms that decribe mapping/normalization methods used in GeneNetwork"))
+ (triples
+ (string->identifier "mappingMethod" (field MappingMethod Name))
+ (set rdf:type 'gnc:mappingMethod)
+ (set rdfs:label (field MappingMethod Name))))
+
+(define-transformer avg-method
+ ;; The Name and Normalization fields seem to be the same. Dump only
+ ;; the Name field.
+ (tables (AvgMethod))
+ (schema-triples
+ (gnc:avgMethod rdf:type owl:Class))
+ (triples (string->identifier "avgmethod" (field AvgMethod Name))
+ (set rdf:type 'gnc:avgMethod)
+ (set rdfs:label (field AvgMethod Normalization))))
+
+
+
+(let* ((option-spec
+ '((settings (single-char #\s) (value #t))
+ (output (single-char #\o) (value #t))
+ (documentation (single-char #\d) (value #t))))
+ (options (getopt-long (command-line) option-spec))
+ (settings (option-ref options 'settings #f))
+ (output (option-ref options 'output #f))
+ (documentation (option-ref options 'documentation #f))
+ (%connection-settings
+ (call-with-input-file settings
+ read)))
+
+ (with-documentation
+ (name "Species Metadata")
+ (connection %connection-settings)
+ (table-metadata? #f)
+ (prefixes
+ '(("gn:" "<http://genenetwork.org/id/>")
+ ("gnc:" "<http://genenetwork.org/category/>")
+ ("owl:" "<http://www.w3.org/2002/07/owl#>")
+ ("gnt:" "<http://genenetwork.org/term/>")
+ ("skos:" "<http://www.w3.org/2004/02/skos/core#>")
+ ("rdf:" "<http://www.w3.org/1999/02/22-rdf-syntax-ns#>")
+ ("rdfs:" "<http://www.w3.org/2000/01/rdf-schema#>")
+ ("taxon:" "<http://purl.uniprot.org/taxonomy/>")))
+ (inputs
+ (list inbred-set species strain mapping-method avg-method))
+ (outputs
+ `(#:documentation ,documentation
+ #:rdf ,output))))
+