path: root/general/datasets/Jax_d2_mono1vpbmc_ret_rna_seq_0619/summary.rtf

<p>Glaucoma is characterized by the progressive dysfunction and loss of retinal ganglion cells. Recent work in animal models suggests that a critical neuroinflammatory event damages retinal ganglion cell axons in the optic nerve head during ocular hypertensive injury. We previously demonstrated that monocyte-like cells enter the optic nerve head in an ocular hypertensive mouse model of glaucoma (DBA/2&thinsp;J), but their roles, if any, in mediating axon damage remain unclear.</p>

<p><a href="https://molecularneurodegeneration.biomedcentral.com/articles/10.1186/s13024-018-0303-3" target="_blank">https://molecularneurodegeneration.biomedcentral.com/articles/10.1186/s13024-018-0303-3</a></p>