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authorBonface2024-02-09 09:41:28 -0600
committerMunyoki Kilyungi2024-08-09 13:30:43 +0300
commitd029d5d7f8ead1f1de8d318045004a4a6f68f5fb (patch)
tree33c7ff40e3f953d030ed08f468f7afb1dfcba9e6 /general/datasets/JAX_D2GM_RSeq_log2Z_0418
parent769ff7825f5d8d36d541e90534c07f1985899973 (diff)
downloadgn-docs-d029d5d7f8ead1f1de8d318045004a4a6f68f5fb.tar.gz
Update dataset RTF Files.
Diffstat (limited to 'general/datasets/JAX_D2GM_RSeq_log2Z_0418')
-rw-r--r--general/datasets/JAX_D2GM_RSeq_log2Z_0418/experiment-design.rtf1
-rw-r--r--general/datasets/JAX_D2GM_RSeq_log2Z_0418/platform.rtf1
-rw-r--r--general/datasets/JAX_D2GM_RSeq_log2Z_0418/specifics.rtf3
-rw-r--r--general/datasets/JAX_D2GM_RSeq_log2Z_0418/summary.rtf1
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diff --git a/general/datasets/JAX_D2GM_RSeq_log2Z_0418/experiment-design.rtf b/general/datasets/JAX_D2GM_RSeq_log2Z_0418/experiment-design.rtf
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+<p>Retinal ganglion cell mRNA from 4 month (young) and 9 month (pre-glaucomatous) DBA/2J mice and age and sex-matched D2-Gpnmb+ controls</p>
diff --git a/general/datasets/JAX_D2GM_RSeq_log2Z_0418/platform.rtf b/general/datasets/JAX_D2GM_RSeq_log2Z_0418/platform.rtf
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+<p><a href="https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GPL17021">GPL17021</a>Illumina HiSeq 2500 (Mus musculus)</p>
diff --git a/general/datasets/JAX_D2GM_RSeq_log2Z_0418/specifics.rtf b/general/datasets/JAX_D2GM_RSeq_log2Z_0418/specifics.rtf
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+<p>RNA-Seq log2 Z-Score</p>
+
+<p>In general, the array data that we put in GeneNetwork has been logged and then z normalized, but instead of leaving the mean at 0 and the standard deviation of 1 unit, we shift up to a mean of 8 units and increase the spread by having an standard deviation of 2 units (what we call 2Z + 8 normalized data). &nbsp;This removes negative values from the tables.</p>
diff --git a/general/datasets/JAX_D2GM_RSeq_log2Z_0418/summary.rtf b/general/datasets/JAX_D2GM_RSeq_log2Z_0418/summary.rtf
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+<p>RNA-seq analysis from young and pre-glaucomatous DBA/2J retinal ganglion cells and control (age and sex-matched, D2-Gpnmb+) retinal ganglion cells</p>