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authorMunyoki Kilyungi2023-10-24 17:01:17 +0300
committerMunyoki Kilyungi2023-10-24 17:01:17 +0300
commit291a0eab8d5585e599d97a28c4b5e1a7653b7cfc (patch)
tree78d50fb47271eaafb85dbdfdcdedecee9fb619dd /api/GN2-API-documentation.md
parent6b9866b77814ad6312665dd67d62c7319cc4a72a (diff)
downloadgn-docs-291a0eab8d5585e599d97a28c4b5e1a7653b7cfc.tar.gz
Rename GN2-API-documentation.md -> GN3-REST-API-Implementation.md.
Signed-off-by: Munyoki Kilyungi <me@bonfacemunyoki.com>
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-# API Endpoints
-
-The following end-points are available to all users. The result of every query is json-ld.
-
-## GET /metadata/species
-
-Returns a list of species.
-
-```
-curl localhost:8080/api/metadata/species
-```
-
-Example Result:
-
-```
-{
- "@context": {
- "alternateName": "skos:altLabel",
- "data": "@graph",
- "family": "gnt:family",
- "fullName": "skos:prefLabel",
- "gnt": "http://genenetwork.org/term/",
- "id": "@id",
- "name": "rdfs:label",
- "rdfs": "http://www.w3.org/2000/01/rdf-schema#",
- "shortName": "gnt:shortName",
- "skos": "http://www.w3.org/2004/02/skos/core#",
- "taxonomicId": "skos:notation",
- "type": "@type"
- },
- "data": [
- {
- "alternateName": "Human",
- "family": "Vertebrates",
- "fullName": "Human (Homo sapiens, hg19)",
- "id": "http://genenetwork.org/id/Homo_sapiens",
- "name": "Homo sapiens",
- "shortName": "human",
- "taxonomicId": {
- "id": "http://purl.uniprot.org/taxonomy/9606"
- }
- },
- [...]
- {
- "alternateName": "Soybean",
- "family": "Plants",
- "fullName": "Soybean (Glycine max, US DOE JGI-PGF v2 2021)",
- "id": "http://genenetwork.org/id/Glycine_max",
- "name": "Glycine max",
- "shortName": "soybean",
- "taxonomicId": {
- "id": "http://purl.uniprot.org/taxonomy/3847"
- }
- }
- ]
-}
-```
-
-## GET /metadata/species/:name
-
-Get a list of species with data available in GN.
-
-```
-curl "localhost:8080/api/metadata/species/bat"
-```
-
-Example Result:
-
-```
-{
- "@context": {
- "alternateName": "skos:altLabel",
- "data": "@graph",
- "family": "gnt:family",
- "fullName": "skos:prefLabel",
- "gnt": "http://genenetwork.org/term/",
- "id": "@id",
- "name": "rdfs:label",
- "rdfs": "http://www.w3.org/2000/01/rdf-schema#",
- "shortName": "gnt:shortName",
- "skos": "http://www.w3.org/2004/02/skos/core#",
- "taxonomicId": "skos:notation",
- "type": "@type"
- },
- "alternateName": "Bat (Glossophaga soricina)",
- "family": "Vertebrates",
- "fullName": "Bat (Glossophaga soricina, gsor23)",
- "id": "http://genenetwork.org/id/Glossophaga_soricina",
- "name": "Glossophaga soricina",
- "shortName": "bat",
- "taxonomicId": {
- "id": "http://purl.uniprot.org/taxonomy/27638"
- }
-}
-
-```
-
-## GET /metadata/groups
-
-Fetch all groups.
-
-```
-curl "localhost:8080/api/metadata/groups"
-```
-
-Example Results:
-
-```
-{
- "@context": {
- "code": "gnt:code",
- "data": "@graph",
- "family": "gnt:family",
- "fullName": "skos:prefLabel",
- "geneticType": "gnt:geneticType",
- "gnt": "http://genenetwork.org/term/",
- "id": "@id",
- "mappingMethod": "gnt:mappingMethod",
- "name": "rdfs:label",
- "rdfs": "http://www.w3.org/2000/01/rdf-schema#",
- "shortName": "gnt:shortName",
- "skos": "http://www.w3.org/2004/02/skos/core#",
- "type": "@type"
- },
- "data": [
- {
- "code": "BDG",
- "family": "BXD Individual Data",
- "fullName": "DOD-BXD-GWI",
- "geneticType": "intercross",
- "id": "http://genenetwork.org/id/setDod-bxd-gwi",
- "mappingMethod": "qtlreaper",
- "name": "BXD DOD Gulf War Illness"
- },
- [...]
- {
- "code": "CAN",
- "fullName": "CANDLE",
- "id": "http://genenetwork.org/id/setCandle",
- "name": "Child Development: CANDLE Cohort with Genotypes (TUCI/UTHSC)"
- }
- ]
-}
-```
-
-## GET /metadata/groups/:name
-
-Fetch information about a given group given a species' name.
-
-```
-curl "localhost:8080/api/metadata/groups/bat"
-```
-
-Example Results:
-
-```
-{
- "@context": {
- "code": "gnt:code",
- "data": "@graph",
- "family": "gnt:family",
- "fullName": "skos:prefLabel",
- "geneticType": "gnt:geneticType",
- "gnt": "http://genenetwork.org/term/",
- "id": "@id",
- "mappingMethod": "gnt:mappingMethod",
- "name": "rdfs:label",
- "rdfs": "http://www.w3.org/2000/01/rdf-schema#",
- "shortName": "gnt:shortName",
- "skos": "http://www.w3.org/2004/02/skos/core#",
- "type": "@type"
- },
- "code": "GSO",
- "fullName": "GSO",
- "id": "http://genenetwork.org/id/setGso",
- "mappingMethod": "qtlreaper",
- "name": "HUB Winter Gsor families (2014-2022)"
-}
-```
-
-
-## GET /metadata/datasets/:name
-
-Fetch information about a given dataset given it's name.
-
-```
-curl "localhost:8080/api/metadata/datasets/IBR_M_0204_M"
-```
-
-or
-
-```
-curl "localhost:8080/api/metadata/datasets/GN11"
-```
-
-Example Results:
-
-```
-{
- "@context": {
- "accessRights": "dct:accessRights",
- "accessionId": "dct:identifier",
- "acknowledgement": "gnt:hasAcknowledgement",
- "altLabel": "skos:altLabel",
- "caseInfo": "gnt:hasCaseInfo",
- "classifiedUnder": "xkos:classifiedUnder",
- "contactPoint": "dcat:contactPoint",
- "created": "dct:created",
- "data": "@graph",
- "dcat": "http://www.w3.org/ns/dcat#",
- "dct": "http://purl.org/dc/terms/",
- "description": "dct:description",
- "ex": "http://example.org/stuff/1.0/",
- "experimentDesignInfo": "gnt:hasExperimentDesignInfo",
- "foaf": "http://xmlns.com/foaf/0.1/",
- "geoSeriesId": "gnt:hasGeoSeriesId",
- "gnt": "http://genenetwork.org/term/",
- "id": "@id",
- "inbredSet": "ex:belongsToInbredSet",
- "info": "ex:info",
- "label": "rdfs:label",
- "normalization": "gnt:usesNormalization",
- "notes": "gnt:hasNotes",
- "organization": "foaf:Organization",
- "platform": "ex:platform",
- "prefLabel": "skos:prefLabel",
- "processingInfo": "gnt:hasDataProcessingInfo",
- "rdfs": "http://www.w3.org/2000/01/rdf-schema#",
- "skos": "http://www.w3.org/2004/02/skos/core#",
- "tissue": "ex:tissue",
- "title": "dct:title",
- "type": "@type",
- "xkos": "http://rdf-vocabulary.ddialliance.org/xkos#"
- },
- "accessionId": "GN11",
- "contactPoint": "Michael Miles",
- "id": "http://genenetwork.org/id/Ibr_m_0204_m",
- "inbredSet": "BXD Family",
- "label": "IBR_M_0204_M",
- "normalization": "MAS5",
- "platform": {
- "id": "http://genenetwork.org/id/platformMoe430",
- "info": "[...]",
- "label": "Affy Mouse Genome 430A, 430B, 430A 2.0 (GPL339,GPL340)",
- "prefLabel": "MOE430",
- "type": "http://genenetwork.org/category/geneChip"
- },
- "tissue": {
- "id": "http://genenetwork.org/id/tissueBrn",
- "info": "[...]",
- "label": "Brain mRNA",
- "type": "http://genenetwork.org/category/tissue"
- },
- "type": "dcat:Dataset"
-}
-```
-
-## GET /metadata/datasets/:group/list
-
-List datasets that belong to a given group.
-
-*Parameters:* page(default=0), per-page(default=10)
-
-```
-curl "localhost:8080/api/metadata/datasets/BXD/list"
-```
-
-Example Results:
-
-```
-{
- "@context": {
- "classifiedUnder": "xkos:classifiedUnder",
- "created": "dct:created",
- "currentPage": "ex:currentPage",
- "data": "@graph",
- "dct": "http://purl.org/dc/terms/",
- "ex": "http://example.org/stuff/1.0/",
- "id": "@id",
- "name": "rdfs:label",
- "pages": "ex:totalCount",
- "rdfs": "http://www.w3.org/2000/01/rdf-schema#",
- "result": "ex:result",
- "resultItem": "ex:resultType",
- "results": "ex:items",
- "title": "dct:title",
- "type": "@type",
- "xkos": "http://rdf-vocabulary.ddialliance.org/xkos#"
- },
- "currentPage": 0,
- "id": "ex:result",
- "pages": 42,
- "results": [
- {
- "created": "2001-09-22",
- "name": "DBA2J-ONH-1212",
- "title": "Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma."
- },
- [...]
- {
- "created": "2003-06-01",
- "name": "Br_U_0603_M"
- }
- ],
- "type": "resultItem"
-}
-```
-
-## GET /metadata/datasets/search/:term
-Search datasets based of it's title.
-
-*Parameters:* page(default=0), per-page(default=10)
-
-```
-curl "localhost:8080/api/metadata/datasets/search/BXD?page=2&limit=3"
-```
-
-Example Results:
-
-```
-{
- "@context": {
- "classifiedUnder": "xkos:classifiedUnder",
- "currentPage": "ex:currentPage",
- "data": "@graph",
- "dataset": "rdfs:label",
- "dct": "http://purl.org/dc/terms/",
- "ex": "http://example.org/stuff/1.0/",
- "id": "@id",
- "inbredSet": "ex:belongsToInbredSet",
- "pages": "ex:totalCount",
- "rdfs": "http://www.w3.org/2000/01/rdf-schema#",
- "result": "ex:result",
- "resultItem": "ex:resultType",
- "results": "ex:items",
- "title": "dct:title",
- "type": "@type",
- "xkos": "http://rdf-vocabulary.ddialliance.org/xkos#"
- },
- "data": [
- {
- "currentPage": 2,
- "id": "ex:result",
- "pages": 46,
- "results": [
- {
- "classifiedUnder": "Phenotype",
- "dataset": "BXD-AEPublish",
- "inbredSet": "BXD Adult and Aged Eye",
- "title": "BXD Adult and Aged Eye Phenotypes"
- },
- {
- "classifiedUnder": "Phenotype",
- "dataset": "BXD-AEPublish",
- "inbredSet": "BXD Adult and Aged Eye",
- "title": "BXD Adult and Aged Eye Phenotypes"
- },
- {
- "classifiedUnder": "Phenotype",
- "dataset": "BXD-BonePublish",
- "inbredSet": "BXD Bone Individual Data",
- "title": "BXD Bone Individual Data"
- }
- ],
- "type": "resultItem"
- }
- ]
-}
-```
-
-## GET /metadata/datasets/search/:term
-Search datasets based of it's title.
-
-*Parameters:* page(default=0), per-page(default=10)
-
-```
-curl "localhost:8080/api/metadata/datasets/search/BXD?page=2&limit=3"
-```
-
-## GET /metadata/publication/:name
-
-Get a publication given it's name. Name can be a pubmedId or a GN-specific identifier for unpublished work.
-
-```
-curl localhost:8080/api/metadata/publications/2760876
-```
-
-Example Result:
-
-```
-{
- "@context": {
- "abstract": "dct:abstract",
- "creator": "dct:creator",
- "dct": "http://purl.org/dc/terms/",
- "fabio": "http://purl.org/spar/fabio/",
- "id": "@id",
- "journal": "fabio:Journal",
- "month": {
- "@id": "prism:publicationDate",
- "@type": "xsd:gMonth"
- },
- "page": "fabio:page",
- "prism": "http://prismstandard.org/namespaces/basic/2.0/",
- "title": "dct:title",
- "type": "@type",
- "volume": "prism:volume",
- "xsd": "http://www.w3.org/2001/XMLSchema#",
- "year": {
- "@id": "fabio:hasPublicationYear",
- "@type": "xsd:gYear"
- }
- },
- "abstract": "Fetal gonadal size [...]",
- "creator": [
- "Argyropoulos G",
- "Shire JG"
- ],
- "id": "http://rdf.ncbi.nlm.nih.gov/pubmed/2760876",
- "journal": "J Reprod Fertil",
- "month": "July",
- "page": "473-478",
- "title": "Genotypic effects on gonadal size in fetal mice",
- "type": "fabio:ResearchPaper",
- "volume": "86(2)",
- "year": "1989"
-}
-```
-
-## GET /metadata/publications/search/:term
-
-Search publications using :term.
-
-```
-curl "localhost:8080/api/metadata/publications/search/BXD?page=0&limit=3"
-```
-
-
-Example Results:
-
-```
-{
- "@context": {
- "currentPage": "ex:currentPage",
- "data": "@graph",
- "dcat": "http://www.w3.org/ns/dcat#",
- "dct": "http://purl.org/dc/terms/",
- "ex": "http://example.org/stuff/1.0/",
- "fabio": "http://purl.org/spar/fabio/",
- "foaf": "http://xmlns.com/foaf/0.1/",
- "generif": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=",
- "genotype": "http://genenetwork.org/genotype/",
- "gn": "http://genenetwork.org/id/",
- "gnc": "http://genenetwork.org/category/",
- "gnt": "http://genenetwork.org/term/",
- "id": "@id",
- "owl": "http://www.w3.org/2002/07/owl#",
- "pages": "ex:totalCount",
- "phenotype": "http://genenetwork.org/phenotype/",
- "prism": "http://prismstandard.org/namespaces/basic/2.0/",
- "publication": "http://genenetwork.org/publication/",
- "pubmed": "fabio:hasPubMedId",
- "rdf": "http://www.w3.org/1999/02/22-rdf-syntax-ns#",
- "rdfs": "http://www.w3.org/2000/01/rdf-schema#",
- "result": "ex:result",
- "resultItem": "ex:resultType",
- "results": "ex:items",
- "skos": "http://www.w3.org/2004/02/skos/core#",
- "taxon": "https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=",
- "title": "dct:title",
- "type": "@type",
- "up": "http://purl.uniprot.org/core/",
- "url": "rdfs:label",
- "xkos": "http://rdf-vocabulary.ddialliance.org/xkos#",
- "xsd": "http://www.w3.org/2001/XMLSchema#"
- },
- "data": [
- {
- "currentPage": 0,
- "id": "ex:result",
- "pages": 2740,
- "results": [
- {
- "title": "A QTL on chromosome 1 modulates inter-male aggression in mice",
- "url": "http://genenetwork.org/id/unpublished14159"
- },
- {
- "title": "\tSystems genetics of metabolism: the use of the BXD murine reference panel for multiscalar integration of traits",
- "url": "http://genenetwork.org/id/unpublished14051"
- },
- {
- "title": "3a,5a-THP in BXD CIE study",
- "url": "http://genenetwork.org/id/unpublished12780"
- }
- ],
- "type": "resultItem"
- }
- ]
-}
-```
-
-## GET /metadata/phenotypes/:name
-Fetch metadata about a given phenotype given it's name.
-
-```
-curl "localhost:8080/api/metadata/phenotypes/BXD_10007"
-```
-
-Example Result:
-
-```
-{
- "@context": {
- "LRS": "gnt:LRS",
- "abbreviation": "dct:abbreviation",
- "abstract": "dct:abstract",
- "additive": "gnt:additive",
- "altName": "rdfs:altLabel",
- "contributor": "dct:contributor",
- "creator": "dct:creator",
- "data": "@graph",
- "dct": "http://purl.org/dc/terms/",
- "description": "dct:description",
- "fabio": "http://purl.org/spar/fabio/",
- "gnc": "http://genenetwork.org/category/",
- "gnt": "http://genenetwork.org/term/",
- "id": "@id",
- "journal": "fabio:Journal",
- "labCode": "gnt:labCode",
- "locus": "gnt:locus",
- "mean": "gnt:mean",
- "month": {
- "@id": "prism:publicationDate",
- "@type": "xsd:gMonth"
- },
- "page": "fabio:page",
- "prism": "http://prismstandard.org/namespaces/basic/2.0/",
- "rdfs": "http://www.w3.org/2000/01/rdf-schema#",
- "references": "dct:isReferencedBy",
- "sequence": "gnt:sequence",
- "skos": "http://www.w3.org/2004/02/skos/core#",
- "submitter": "gnt:submitter",
- "title": "dct:title",
- "trait": "rdfs:label",
- "traitName": "skos:altLabel",
- "type": "@type",
- "volume": "prism:volume",
- "xsd": "http://www.w3.org/2001/XMLSchema#",
- "year": {
- "@id": "fabio:hasPublicationYear",
- "@type": "xsd:gYear"
- }
- },
- "LRS": 14.3203,
- "abstract": "To discover [...]",
- "additive": 1.24101,
- "creator": [
- "Airey DC",
- "Williams RW",
- "Lu L"
- ],
- "description": "Central nervous system, morphology: Internal granule layer IGL of the cerebellum volume, adjusted for sex, age, body and brain weight [mm3]",
- "gnt:abbreviation": "AdjIGLVol",
- "http://example.org/stuff/1.0/inbredSet": "BXD Family",
- "http://example.org/stuff/1.0/species": "Mouse (Mus musculus, mm10)",
- "id": "http://genenetwork.org/id/traitBxd_10007",
- "journal": "J Neurosci",
- "locus": "rsm10000005700",
- "mean": 18.2129,
- "month": "Jul",
- "page": "5099-5109",
- "references": {
- "id": "http://rdf.ncbi.nlm.nih.gov/pubmed/11438585"
- },
- "sequence": 1,
- "submitter": "robwilliams",
- "title": "Genetic control of the mouse cerebellum: identification of quantitative trait loci modulating size and architecture",
-
- "trait": "10007",
- "traitName": "BXD_10007",
- "type": "gnc:Phenotype",
- "volume": "21(14)",
- "year": "2001"
-}
-```
-
-## GET /metadata/phenotypes/:group/:name
-Fetch metadata about a given phenotype given it's group and name.
-
-```
-curl "localhost:8080/api/metadata/phenotypes/BXD/10007"
-```
-
-Example Result:
-
-```
-{
- "@context": {
- "LRS": "gnt:LRS",
- "abbreviation": "dct:abbreviation",
- "abstract": "dct:abstract",
- "additive": "gnt:additive",
- "altName": "rdfs:altLabel",
- "contributor": "dct:contributor",
- "creator": "dct:creator",
- "data": "@graph",
- "dct": "http://purl.org/dc/terms/",
- "description": "dct:description",
- "fabio": "http://purl.org/spar/fabio/",
- "gnc": "http://genenetwork.org/category/",
- "gnt": "http://genenetwork.org/term/",
- "id": "@id",
- "journal": "fabio:Journal",
- "labCode": "gnt:labCode",
- "locus": "gnt:locus",
- "mean": "gnt:mean",
- "month": {
- "@id": "prism:publicationDate",
- "@type": "xsd:gMonth"
- },
- "page": "fabio:page",
- "prism": "http://prismstandard.org/namespaces/basic/2.0/",
- "rdfs": "http://www.w3.org/2000/01/rdf-schema#",
- "references": "dct:isReferencedBy",
- "sequence": "gnt:sequence",
- "skos": "http://www.w3.org/2004/02/skos/core#",
- "submitter": "gnt:submitter",
- "title": "dct:title",
- "trait": "rdfs:label",
- "traitName": "skos:altLabel",
- "type": "@type",
- "volume": "prism:volume",
- "xsd": "http://www.w3.org/2001/XMLSchema#",
- "year": {
- "@id": "fabio:hasPublicationYear",
- "@type": "xsd:gYear"
- }
- },
- "LRS": 14.3203,
- "abstract": "To discover [...]",
- "additive": 1.24101,
- "creator": [
- "Airey DC",
- "Williams RW",
- "Lu L"
- ],
- "description": "Central nervous system, morphology: Internal granule layer IGL of the cerebellum volume, adjusted for sex, age, body and brain weight [mm3]",
- "gnt:abbreviation": "AdjIGLVol",
- "http://example.org/stuff/1.0/inbredSet": "BXD Family",
- "http://example.org/stuff/1.0/species": "Mouse (Mus musculus, mm10)",
- "id": "http://genenetwork.org/id/traitBxd_10007",
- "journal": "J Neurosci",
- "locus": "rsm10000005700",
- "mean": 18.2129,
- "month": "Jul",
- "page": "5099-5109",
- "references": {
- "id": "http://rdf.ncbi.nlm.nih.gov/pubmed/11438585"
- },
- "sequence": 1,
- "submitter": "robwilliams",
- "title": "Genetic control of the mouse cerebellum: identification of quantitative trait loci modulating size and architecture",
- "trait": "10007",
- "traitName": "BXD_10007",
- "type": "gnc:Phenotype",
- "volume": "21(14)",
- "year": "2001"
-}
-```
-
-## GET /metadata/genotypes/:name
-Fetch metadata about a given genotype given it's name.
-
-```
-curl "localhost:8080/api/metadata/genotypes/D1Mit3"
-```
-
-Example Result
-
-```
-{
- "@context": {
- "alternateSource": "gnt:hasAltSourceName",
- "chr": "gnt:chr",
- "chrNum": {
- "@id": "gnt:chrNum",
- "@type": "xsd:int"
- },
- "comments": "rdfs:comments",
- "data": "@graph",
- "gnc": "http://genenetwork.org/category/",
- "gnt": "http://genenetwork.org/term/",
- "id": "@id",
- "mb": "gnt:mb",
- "mb2016": "gnt:mb2016",
- "mbMm8": "gnt:mbMm8",
- "name": "rdfs:label",
- "rdfs": "http://www.w3.org/2000/01/rdf-schema#",
- "sequence": "gnt:hasSequence",
- "source": "gnt:hasSource",
- "species": "xkos:classifiedUnder",
- "type": "@type",
- "xkos": "http://rdf-vocabulary.ddialliance.org/xkos#",
- "xsd": "http://www.w3.org/2001/XMLSchema#"
- },
- "chr": "1",
- "chrNum": "1",
- "id": "http://genenetwork.org/id/D1mit3",
- "mb": 19.812,
- "mb2016": 19.8021,
- "mbMm8": 19.7972,
- "name": "D1Mit3",
- "sequence": "TTTAGCAATGGGTANCGGGGATCTTCCACTGTCTTTGTGTCTTAGGACCCAGAATTTACTTTTCTTTTTGTTTTCTTTTCTTTTCCCTGTCTTTTTTTTTTTTTGCTTCTTTTATTTTAAAAATCTATTCATGTTTAAAGTCTCCCTCTCTGTCTCTCTGTCTGTCTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCCAGTACATGTGGAAACCAGAAGAGGGCATCAGATTCCTAGGAACTGGAGCTACAGAT",
- "source": "Mit",
- "species": {
- "id": "http://genenetwork.org/id/Mus_musculus",
- "name": "Mus musculus"
- },
- "type": "gnc:Genotype"
-}
-```
-
-## GET /genewiki/gn/:symbol
-Get genewiki entries from Genetwork about a given symbol
-
-*Parameters:* page(default=0), per-page(default=10)
-
-```
-curl "localhost:8080/api/metadata/genewikis/gn/Lpl"
-```
-
-Example Result
-
-```
-{
- "@context": {
- "author": "dct:creator",
- "category": "gnt:belongsToCategory",
- "comment": "rdfs:comment",
- "created": {
- "@id": "dct:created",
- "@type": "xsd:datetime"
- },
- "currentPage": "ex:currentPage",
- "data": "@graph",
- "dct": "http://purl.org/dc/terms/",
- "entries": "ex:entries",
- "ex": "http://example.org/stuff/1.0/",
- "gnc": "http://genenetwork.org/category/",
- "gnt": "http://genenetwork.org/term/",
- "id": "@id",
- "pages": "ex:totalCount",
- "pubmed": "dct:references",
- "rdfs": "http://www.w3.org/2000/01/rdf-schema#",
- "type": "@type",
- "xsd": "http://www.w3.org/2001/XMLSchema#"
- },
- "currentPage": 0,
- "entries": [
- {
- "category": "Genetic variation and alleles",
- "comment": "Individual probe analysis:probably true cisQTL",
- "created": "2007-10-05T09:09:52",
- "ex:species": "Mouse (Mus musculus, mm10)",
- "pubmed": ""
- },
- {
- "category": "Expression patterns: mature cells, tissues; Gene structure and organization; Genetic variation and alleles",
- "comment": "cis QTL present in hippocampus LXS, ILM2970706 distal 3' UTR, 121.4 LRS, ISS increases the trait;",
- "created": "2007-05-10T05:52:22",
- "ex:species": "Mouse (Mus musculus, mm10)",
- "pubmed": ""
- },
- {
- "category": "",
- "comment": "hippocampal CA1-3 expression signature",
- "created": "2005-12-16T15:23:23",
- "ex:species": "Mouse (Mus musculus, mm10)",
- "pubmed": "http://rdf.ncbi.nlm.nih.gov/pubmed/15084669"
- },
- {
- "category": "Probes and probe sets; Transcriptional and translation control",
- "comment": "Validated strong cis-QTL in CNS using allele-specific expression ASE SNaPshot assay Daniel Ciobanu and al., 2007. Possible 3' UTR variants.",
- "created": "2007-05-08T09:46:07",
- "ex:species": "Mouse (Mus musculus, mm10)",
- "pubmed": ""
- },
- {
- "author": "Robert Williams",
- "category": "Genetic variation and alleles",
- "comment": "cis eQTL in BXD brain RNA-seq data with LRS of 33 and high D allele. No obvious trans target transcripts.",
- "created": "2012-11-10T07:30:09",
- "ex:species": "Mouse (Mus musculus, mm10)",
- "pubmed": ""
- },
- {
- "category": "Health and disease associations",
- "comment": "Merck, Rosetta, Schadt, Lusis target gene associated with obesity, diabetes and atherosclerosis.",
- "created": "2008-05-13T08:48:50",
- "ex:species": "Mouse (Mus musculus, mm10)",
- "pubmed": ""
- },
- {
- "author": "Robert Williams",
- "category": "",
- "comment": "Of interest to Lu Lu and colleagues 2015 due to modulation of expression of this gene in hippocampus following stress or ethanol BXD Illumina Hippocampus data sets.",
- "created": "2015-05-26T11:37:57",
- "ex:species": "Mouse (Mus musculus, mm10)",
- "pubmed": ""
- }
- ],
- "id": "http://genenetwork.org/id/symbolLpl",
- "pages": 1,
- "type": "gnc:GNWikiEntry"
-}
-```
-
-## GET /genewiki/ncbi/:symol
-Get genewiki entries from NCBI about a given symbol
-
-*Parameters:* page(default=0), per-page(default=10)
-
-```
-curl "localhost:8080/api/metadata/genewikis/ncbi/Lpl"
-```
-
-Example Result
-
-```
-{
- "@context": {
- "author": "dct:creator",
- "category": "gnt:belongsToCategory",
- "comment": "rdfs:comment",
- "created": {
- "@id": "dct:created",
- "@type": "xsd:datetime"
- },
- "currentPage": "ex:currentPage",
- "data": "@graph",
- "dct": "http://purl.org/dc/terms/",
- "entries": "ex:entries",
- "ex": "http://example.org/stuff/1.0/",
- "gnc": "http://genenetwork.org/category/",
- "gnt": "http://genenetwork.org/term/",
- "id": "@id",
- "pages": "ex:totalCount",
- "pubmed": "dct:references",
- "rdfs": "http://www.w3.org/2000/01/rdf-schema#",
- "type": "@type",
- "xsd": "http://www.w3.org/2001/XMLSchema#"
- },
- "data": [
- {
- "currentPage": 0,
- "entries": [
- {
- "comment": "Results support the use of LPL and ADAM29 gene expression associated to IGHV mutational status for predicting the clinical outcome of patients treated by oral fludarabine + cyclophosphamide and could be considered for treatment strategies.",
- "created": "2010-01-20T18:00:00",
- "ex:species": "Human (Homo sapiens, hg19)",
- "gnt:hasGeneId": {
- "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=4023"
- },
- "pubmed": ""
- },
- {
- "comment": "Observational study of gene-disease association and pharmacogenomic / toxicogenomic. HuGE Navigator",
- "created": "2009-02-11T15:30:00",
- "ex:species": "Human (Homo sapiens, hg19)",
- "gnt:hasGeneId": {
- "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=4023"
- },
- "pubmed": ""
- },
- {
- "comment": "analysis of human placental lipoprotein lipase gestational and hormonal regulation",
- "created": "2010-01-20T18:00:00",
- "ex:species": "Human (Homo sapiens, hg19)",
- "gnt:hasGeneId": {
- "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=4023"
- },
- "pubmed": ""
- },
- {
- "comment": "LPL 44X alleles were associated with moderately increased LDL peak particle size.",
- "created": "2010-01-20T18:00:00",
- "ex:species": "Human (Homo sapiens, hg19)",
- "gnt:hasGeneId": {
- "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=4023"
- },
- "pubmed": ""
- },
- {
- "comment": "LPL gene variant is involved in carotid atherosclerotic lesions.",
- "created": "2010-01-20T18:00:00",
- "ex:species": "Human (Homo sapiens, hg19)",
- "gnt:hasGeneId": {
- "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=4023"
- },
- "pubmed": ""
- },
- {
- "comment": "Metformin may increase LPL production, thereby increasing low density lipoprotein particle size which may be independent of the hypoglycemic effect of metforminin type 2 diabetes.",
- "created": "2010-01-20T18:00:00",
- "ex:species": "Human (Homo sapiens, hg19)",
- "gnt:hasGeneId": {
- "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=4023"
- },
- "pubmed": ""
- },
- {
- "comment": "LPL may represent a link between low adiponectin levels and dyslipidemia in both nondiabetic individuals and patients with type 2 diabetes.",
- "created": "2010-01-20T18:00:00",
- "ex:species": "Human (Homo sapiens, hg19)",
- "gnt:hasGeneId": {
- "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=4023"
- },
- "pubmed": ""
- },
- {
- "comment": "The PvuII polymorphism cannot be used as independent genetic risk factor for coronary artery disease in patients of Saudi Arabic descent.",
- "created": "2010-01-20T18:00:00",
- "ex:species": "Human (Homo sapiens, hg19)",
- "gnt:hasGeneId": {
- "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=4023"
- },
- "pubmed": ""
- }
- ],
- "id": "http://genenetwork.org/id/symbolLPL",
- "pages": 48,
- "type": "gnc:GNWikiEntry"
- },
- {
- "currentPage": 0,
- "entries": [
- {
- "comment": "LPL activity can be inhibited by endogenous apoC-I in apoE-knockout mice.",
- "created": "2010-01-20T18:00:00",
- "ex:species": "Mouse (Mus musculus, mm10)",
- "gnt:hasGeneId": {
- "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=16956"
- },
- "pubmed": ""
- },
- {
- "comment": "STZ-induced diabetes causes a decrease in LPL activity in the sciatic nerve that is reversible with insulin treatment",
- "created": "2010-01-20T18:00:00",
- "ex:species": "Rat (Rattus norvegicus, rn7.2)",
- "gnt:hasGeneId": {
- "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=24539"
- },
- "pubmed": ""
- }
- ],
- "id": "http://genenetwork.org/id/symbolLpl",
- "pages": 48,
- "type": "gnc:GNWikiEntry"
- }
- ]
-}
-```