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+{
+  "titles": [
+    "2004 - Diabetes Genes a.pdf",
+    "2016 - NIH working group report using genomic information to guide weight management  From universal.pdf",
+    "2012 - Diabetes and Hypertension Is There a Common Metabolic Pathway.pdf",
+    "2004 - Diabetes Genes a.pdf",
+    "2004 - Diabetes Genes b.pdf",
+    "2004 - Diabetes Genes a.pdf",
+    "2005 - Metabolic Syndrome A Comprehensive Perspective Based  on Interactions Between Obesity Diabetes and Inflammation.pdf",
+    "2017 - diabetes-mellitus-in-developing-countries-and-underserved-commun-2017.pdf",
+    "2004 - Diabetes Genes a.pdf",
+    "2018 - Type 2 Diabetes in adolescents and young adults.pdf"
+  ],
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+    "2 diabetes suggest that regular exercise might play an important role in  decreasing the very high incidence of premature coronary artery disease.  Although there are no randomized controlled trials assessing reduction  in cardiovascular events induced by physical activity in type 2 diabetes,  available evidence is consistent with the concept that physical activity may play  an important role in reducing cardiovascular risk in type 2 diabetes. 44 Large",
+    "tern of weight change impact health. For example, in the DiabetesPrevention Program (DPP; described in more detail later), both short- and intermediate-term weight loss were associated with reduced diabetes risk and intermediate cardiometabolic risk factor levels, whereas weight cycling (defined as number of 5 lb [2.25 kg] weight cycles) raised diabetes risk, fasting glucose levels, insulinresistance, and systolic blood pressure. Initial (baseline to 1 month)",
+    "sclerosis Risk in Communities (ARIC) study, the highestquartile of leisure activity (primarily cycling and walking)had a 34% lower odds of developing hypertension over 6 years compared to the least active [ 107]. Thus, physical activity reduces the risk of developing diabetes and hyper- tension. The mechanism involves changes in body weight and glucose tolerance, as well as other factors [ 107]. The effect of obesity susceptibility genes on the onset of",
+    "exercise can reduce the incidence of type 2 diabetes. Tuomilehto and  coworkers demonstrated that the individuals on a consistent diet and exercise  program had 10% incidence of diabetes during 4 years of follow-up  compared to 22% for patients in the control group, who met only once a year  with the dietician and the physician.40 A six-year randomized trial conducted  by Pan and colleagues demonstrated that exercise resulted in 46% reduction",
+    "Exercise  Exercise has been shown to prevent development of Type 2  diabetes in high-risk groups. A number of studies have looked at the effect  of insulin on delaying the onset of diabetes. In a study of 5990 male  alumni from an American university followed over 10 years, 202 pts (3.3  percent) developed Type 2 diabetes mellitus. The relative risk was lower  in patients who exercised regularly even when adjusted for obesity,  hypertension, and a family history of diabetes. The benefit was greatest in",
+    "nonrandomized studies of both men and women with type 2 diabetes and  impaired glucose tolerance have found that physical activity is associated with  a decreased risk for cardiovascular disease. It also appears that the amount of  physical activity is inversely associated with coronary events.5354  RISK OF EXERCISE IN PATIENTS WITH DIABETES  The risks associated with exercise can be divided into metabolic,  vascular, neurologic and musculoskeletal (Table 4).",
+    "74 The mechanism underlying this effect of exercise is not known;however, it is noteworthy that lifestyle change is a very effectiveway to reduce the rate of development of diabetes in a predia-betic population, as shown by the diabetes prevention study. 75,76 Both a reduction in macronutrient intake and exercise cause areduction in inflammation. References 1. Reaven GM. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes . 1988;37:15951607.",
+    "physical training on carbohydrate metabolism and associated cardiovascular risk factors in patients with diabetes. Diabetes Rev. 1995;3:378407.      23.    Rogers MA, Yamamoto C, King DS, Harberg JM,  Ensani AA, Holloszy JO. Improvement in glucose tolerance after one week of exercise in patients with mild NIDDM. Diabetes Care. 1988;11:6138.      24.    Eriksson KF, Lindgarde F. Prevention of type 2 dia- betes mellitus by diet and physical exercise. Diabetologia. 1991;34:8918.",
+    "migrant and other observational studie!f86970 and prospective studies in subjects  at high risk for developing type 2 diabetes.717273 Recently, large interventional  trials have reinforced the benefits of exercise in reducing the risk for type 2  diabetes. These include the Malmo study from Sweden45, the Da Quing study  from China74 and the recently concluded Finnish Diabetes Prevention Study.75  These prospective but not randomized studies show a reduction in the risk of  560",
+    "reduce systolic blood pressure, reduce total cholesterol, raise HDL cholesterol, and improve endothelial function in overweight patients with young-onset type 2 diabetes. 47  However, any potential benefits to the cardiovascular disease risk profile are lost within 36 months after cessation of exercise training, and do not confer protection against later cardiovascular events. 47,121 Additionally,  reviews49,121,122 of the limited number of studies done to"
+  ],
+  "answer": "Yes, cycling, as a form of physical activity, can reduce the risk of diabetes. According to the context provided:  - The Atherosclerosis Risk in Communities (ARIC) study found that higher levels of leisure activity, which primarily included cycling and walking, were associated with a 34% lower odds of developing hypertension over six years compared to the least active group. This study also indicated that physical activity reduces the risk of developing diabetes and hypertension through mechanisms involving changes in body weight and glucose tolerance [3]. - Additionally, other studies have shown that exercise, including activities like cycling, can prevent the development of Type 2 diabetes in high-risk groups [5].  Thus, engaging in regular cycling can contribute to a reduced risk of developing diabetes.",
+  "question": "Does cycling reduce risk of diabetes?"
+}
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