diff options
Diffstat (limited to 'scripts')
| -rwxr-xr-x | scripts/update_rif_table.py | 179 |
1 files changed, 93 insertions, 86 deletions
diff --git a/scripts/update_rif_table.py b/scripts/update_rif_table.py index 8566d60..e7cfa08 100755 --- a/scripts/update_rif_table.py +++ b/scripts/update_rif_table.py @@ -28,103 +28,110 @@ Script responsible for updating the GenerRIF_BASIC table """ +import argparse +import csv import os +import gzip +import pathlib import sys +from tempfile import TemporaryDirectory +from typing import Generator, List +import requests + import MySQLdb -path1 = os.path.abspath(os.path.dirname(__file__)) -path2 = path1 + "/.." -path3 = path1 + "/../../tmp" -sys.path.insert(0, path2) +from gn3.db_utils import database_connection + +TAX_IDS = {"10090": 1, "9606": 4, "10116": 2, "3702": 3} + +# os.chdir(path3) + + +def download_file(url: str, dest: pathlib.Path): + """Saves the contents of url in dest""" + with requests.get(url, stream=True) as resp: + resp.raise_for_status() + with open(dest, "wb") as f_: + for chunk in resp.iter_content(chunk_size=8192): + f_.write(chunk) -def fetchrif(): - """ TODO: break this down into modules """ - try: - con = MySQLdb.Connect(db="gn3", host="localhost", user="gn2", passwd="password") - cursor = con.cursor() - print("You have successfully connected to mysql.\n") - except: - print("You entered incorrect password.\n") - sys.exit(0) +def read_tsv_file(fname: pathlib.Path) -> Generator[dict]: + with gzip.open(fname, mode="rt") as gz_file: + reader = csv.DictReader(gz_file, delimiter="\t", quoting=csv.QUOTE_NOTE) + yield from reader - tax_ids = {"10090": 1, "9606": 4, "10116": 2, "3702": 3} - tax_id_keys = tax_ids.keys() - os.chdir(path3) - print(f"path3: {path3}") +def parse_gene_info_from_ncbi(fname: pathlib.Path): genedict = {} + for row in read_tsv_file(fname): + if row["#task_id"] not in TAX_IDS: + continue + genedict[row["GeneID"]] = genedict[row["Symbol"]] + return genedict - os.system("rm -vf gene_info") - os.system("wget ftp://ftp.ncbi.nlm.nih.gov/gene/DATA/gene_info.gz") - os.system("gunzip gene_info.gz") - - with open("gene_info", "r") as file: - i = 0 - for line1 in file: - line1 = line1.strip() - if line1.startswith("#"): - continue - line2 = line1.strip().split("\t") - if line2[0] in tax_id_keys: - genedict[line2[1]] = line2[2] - i += 1 - if i % 1000000 == 0: - print(f"finished: {i}") - print(f"finished all: {i}") - - os.system("rm -vf generifs_basic") - os.system("wget ftp://ftp.ncbi.nlm.nih.gov/gene/GeneRIF/generifs_basic.gz") - os.system("gunzip generifs_basic.gz") - - with open("generifs_basic", "r") as file: - i = 0 - for line1 in file: - line1 = line1.strip() - if line1.startswith("#"): - continue - line2 = line1.strip().split("\t") - if line2[0] in tax_id_keys and len(line2) >= 5: - line2[0] = tax_ids[line2[0]] - try: - symbol = genedict[line2[1]] - except: - symbol = "" - sql = """ - SELECT COUNT(*) - FROM GeneRIF_BASIC - WHERE GeneRIF_BASIC.`SpeciesId`=%s - AND GeneRIF_BASIC.`GeneId`=%s - AND GeneRIF_BASIC.`PubMed_ID`=%s - AND GeneRIF_BASIC.`createtime`=%s - AND GeneRIF_BASIC.`comment`=%s - """ - cursor.execute(sql, (line2[0], line2[1], line2[2], line2[3], line2[4])) - count = cursor.fetchone()[0] - if count == 0: - print("to insert...") - sql = """ - INSERT INTO GeneRIF_BASIC - SET GeneRIF_BASIC.`SpeciesId`=%s, - GeneRIF_BASIC.`GeneId`=%s, - GeneRIF_BASIC.`symbol`=%s, - GeneRIF_BASIC.`PubMed_ID`=%s, - GeneRIF_BASIC.`createtime`=%s, - GeneRIF_BASIC.`comment`=%s - """ - cursor.execute( - sql, (line2[0], line2[1], symbol, line2[2], line2[3], line2[4]) - ) - i += 1 - if i % 100000 == 0: - print(f"finished: {i}") - print(f"finished all: {i}") - cursor.close() +def update_rif(sqluri: str): + """TODO: break this down into modules""" + with TemporaryDirectory() as tmpdir: + gene_info_path = tmpdir / "gene_info.gz" + download_file( + "https://ftp.ncbi.nlm.nih.gov/gene/DATA/gene_info.gz", gene_info_path + ) + + generif_basics_path = pathlib.Path("/tmp/generif_basics.gz") + download_file( + "https://ftp.ncbi.nih.gov/gene/GeneRIF/generifs_basic.gz", + generif_basics_path, + ) + + genedict = parse_gene_info_from_ncbi(gene_info_path) + count_check_query = """ + SELECT COUNT(*) + FROM GeneRIF_BASIC + WHERE GeneRIF_BASIC.`SpeciesId`=%s + AND GeneRIF_BASIC.`GeneId`=%s + AND GeneRIF_BASIC.`PubMed_ID`=%s + AND GeneRIF_BASIC.`createtime`=%s + AND GeneRIF_BASIC.`comment`=%s + """ + insert_query = """ + INSERT INTO GeneRIF_BASIC + SET GeneRIF_BASIC.`SpeciesId`=%s, + GeneRIF_BASIC.`GeneId`=%s, + GeneRIF_BASIC.`symbol`=%s, + GeneRIF_BASIC.`PubMed_ID`=%s, + GeneRIF_BASIC.`createtime`=%s, + GeneRIF_BASIC.`comment`=%s + """ + + with database_connection(sql_uri=sqluri) as con: + with con.cursor() as cursor: + for row in read_tsv_file(generif_basics_path): + if row["#Tax ID"] not in TAX_IDS: + continue + row["#Tax ID"] = TAX_IDS[row["#Tax ID"]] + symbol = genedict.get(row["Gene ID"], "") + insert_values = ( + row["#Tax ID"], + symbol, + row["PubMed ID (PMID) list"], + row["last update timestamp"], + row["GeneRIF text"], + ) + cursor.execute(count_check_query, insert_values) + count = cursor.fetchone()[0] + if count != 0: + continue + cursor.execute(insert_query, insert_values) -# /usr/bin/python addRif.py if __name__ == "__main__": - print(f"command line arguments:\n\t{sys.argv}") - fetchrif() - print("exit successfully") + parser = argparse.ArgumentParser("Update Generif_BASIC table") + parser.add_argument( + "--sql-uri", + required=True, + help="MYSQL uri path in the form mysql://user:password@localhost/gn2", + ) + args = parser.parse_args() + update_rif(args.sql_uri) |