web/tutorial/ppt/WebQTLDemo_files/slide0057.htm


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<title>PowerPoint Presentation  -  Complex trait analysis, develop-ment, and
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mso-text-indent-alt:0'><span style='font-size:68%'><i>Is there known biology to
link Hars2 with App? </i></span></div>

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<div><span style='font-size:150%;color:#E9EB5D;mso-color-index:3'><b>69 SNPs, 1
cSNP: <br>
</b></span></div>

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<div><span style='font-size:150%;color:#E9EB5D;mso-color-index:3'><b>6 exons in
NCBI, <br>
</b></span></div>

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<div><span style='font-size:150%;color:#E9EB5D;mso-color-index:3'><b>2 exons in
Celera</b></span></div>

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mso-text-raise:0%'><span style='font-family:"Gill Sans";font-size:250%;
color:#E9EB5D'><i><span style="mso-spacerun: yes">&nbsp;</span>Not obvious</i></span></div>

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  <tr>
   <td colspan=1></td>
   <td align=left colspan=1><font face=Helvetica size=3>Hars2 is not a well
   characterized gene and their is no biology yet to support the hypothesis
   that Hars2 modulates gene expression, let alone App expression in specific.
   There are also serious database/assembly discrepancies between Celera and
   MGSCv3 regarding the genomic organization of this gene. But there appear to
   be approximately 69 SNPs in Hars2, one of which results in a substitution.</font><br>
   </td>
  </tr>
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