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<title>PowerPoint Presentation - Complex trait analysis, develop-ment, and
genomics</title>
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<div id=SlideObj class=sld style='position:absolute;top:0px;left:0px;
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visibility:hidden'><img src="master03_background.png" v:shapes="_x0000_s1026"
style='position:absolute;top:0%;left:0%;width:100.0%;height:100.0%'>
<div style='position:absolute;top:-.35%;left:3.31%;width:93.64%;height:14.48%;
filter:DropShadow(Color=#000000, OffX=1, OffY=1)'>
<div class=B style='mso-line-spacing:"-220 0 -216";mso-margin-left-alt:292;
mso-text-indent-alt:0;position:absolute;top:0%;left:1.13%;width:97.59%;
height:51.21%'><span style='mso-special-format:nobullet;display:none;
color:#FBFDB8;font-family:"Monotype Sorts";font-size:99%'>l</span><span
style='font-size:106%;color:#E9EB5D;mso-color-index:3'>Summary of Part 2</span><span
style='font-size:94%;color:#E9EB5D;mso-color-index:3;mso-special-format:lastCR;
display:none'><br>
</span></div>
</div>
<div style='position:absolute;top:15.01%;left:5.96%;width:101.19%;height:31.09%'>
<div class=O1 style='mso-margin-left-alt:432'></div>
<div class=O2 style='mso-margin-left-alt:720'></div>
<div class=O3 style='mso-margin-left-alt:1008'></div>
<div class=O4 style='mso-margin-left-alt:1296'></div>
<div class=O style='mso-margin-left-alt:144;position:absolute;top:0%;
left:0%;width:86.25%;height:14.2%'><span style='position:absolute;top:0%;
left:2.88%;width:97.11%'><span style='font-family:"Gill Sans";font-size:167%;
color:#E9EB5D;mso-color-index:3'><span style='mso-special-format:"numbullet3\,1";
position:absolute;left:-2.96%;font-family:Arial'>1.</span></span><span
style='font-family:"Gill Sans";font-size:167%;color:#E9EB5D;mso-color-index:
3'><span style="mso-spacerun: yes"> </span>Covered the basics of QTL
analysis and mapping.<br>
</span></span></div>
<div class=O style='mso-margin-left-alt:144;position:absolute;top:14.2%;
left:0%;width:86.25%;height:14.2%'><span style='position:absolute;top:0%;
left:2.88%;width:97.11%'><span style='font-family:"Gill Sans";font-size:167%;
color:#E9EB5D;mso-color-index:3'><span style='mso-special-format:"numbullet3\,1";
position:absolute;left:-2.96%;font-family:Arial'>2.</span></span><span
style='font-family:"Gill Sans";font-size:167%;color:#E9EB5D;mso-color-index:
3'><span style="mso-spacerun: yes"> </span>Reviewed difference between
genetic and physical maps.<br>
</span></span></div>
<div class=O style='mso-margin-left-alt:144;position:absolute;top:28.4%;
left:0%;width:100.0%;height:42.61%'><span style='position:absolute;top:0%;
left:2.48%;width:97.51%'><span style='font-family:"Gill Sans";font-size:167%;
color:#E9EB5D;mso-color-index:3'><span style='mso-special-format:"numbullet3\,1";
position:absolute;left:-2.55%;font-family:Arial'>3.</span></span><span
style='font-family:"Gill Sans";font-size:167%;color:#E9EB5D;mso-color-index:
3'><span style="mso-spacerun: yes"> </span>Discussed interpreting features
of QTL maps including the LRS function, </span></span><span style='position:
absolute;top:33.33%;left:2.48%;width:91.23%'><span style='font-family:"Gill Sans";
font-size:167%;color:#E9EB5D;mso-color-index:3'>the additive effect function,
the bootstrap bars, and the permutation </span></span><span style='position:
absolute;top:68.0%;left:2.48%;width:83.76%'><span style='font-family:"Gill Sans";
font-size:167%;color:#E9EB5D;mso-color-index:3'>thresholds.<br>
</span></span></div>
<div class=O style='mso-margin-left-alt:144;position:absolute;top:71.59%;
left:0%;width:88.35%;height:14.2%'><span style='position:absolute;top:0%;
left:2.81%;width:97.18%'><span style='font-family:"Gill Sans";font-size:167%;
color:#E9EB5D;mso-color-index:3'><span style='mso-special-format:"numbullet3\,1";
position:absolute;left:-2.89%;font-family:Arial'>4.</span></span><span
style='font-family:"Gill Sans";font-size:167%;color:#E9EB5D;mso-color-index:
3'><span style="mso-spacerun: yes"> </span>Illustrated techniques to
generate a list of positional candidates.<br>
</span></span></div>
<div class=O style='mso-margin-left-alt:144;position:absolute;top:85.79%;
left:0%;width:86.25%;height:14.2%'><span style='position:absolute;top:0%;
left:2.88%;width:97.11%'><span style='font-family:"Gill Sans";font-size:167%;
color:#E9EB5D;mso-color-index:3'><span style='mso-special-format:"numbullet3\,1";
position:absolute;left:-2.96%;font-family:Arial'>5.</span></span><span
style='font-family:"Gill Sans";font-size:167%;color:#E9EB5D;mso-color-index:
3'><span style="mso-spacerun: yes"> </span>Discussed some factors used to
evaluate candidate genes.</span></span></div>
</div>
<div class=O style='position:absolute;top:58.65%;left:5.96%;width:106.22%;
height:22.26%'><span style='position:absolute;top:0%;left:0%;width:84.53%'><span
style='font-family:"Gill Sans";font-size:167%;color:#E9EB5D;mso-color-index:
3'>What does a QTL signify? A good QTL is a claim that a particular </span></span><span
style='position:absolute;top:19.84%;left:0%;width:96.38%'><span
style='font-family:"Gill Sans";font-size:167%;color:#E9EB5D;mso-color-index:
3'>chromosomal region contains a causal source of variation in the phenotype. </span></span><span
style='position:absolute;top:39.68%;left:0%;width:100.0%'><span
style='font-family:"Gill Sans";font-size:167%;color:#E9EB5D;mso-color-index:
3'>The importance of this hypothesis depends on the quality and relevance of
the </span></span><span style='position:absolute;top:59.52%;left:0%;width:90.89%'><span
style='font-family:"Gill Sans";font-size:167%;color:#E9EB5D;mso-color-index:
3'>phenotype and the statistical strength of the QTL. As usual, test and be </span></span><span
style='position:absolute;top:79.36%;left:0%;width:84.53%'><span
style='font-family:"Gill Sans";font-size:167%;color:#E9EB5D;mso-color-index:
3'>skeptical.</span></span></div>
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