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-rwxr-xr-xscripts/maintenance/QTL_Reaper_v6.py10
-rw-r--r--scripts/maintenance/Update_Case_Attributes_MySQL_tab.py2
-rwxr-xr-xscripts/maintenance/delete_genotypes.py16
-rwxr-xr-xscripts/maintenance/delete_phenotypes.py14
-rwxr-xr-xscripts/maintenance/load_genotypes.py20
-rwxr-xr-xscripts/maintenance/load_phenotypes.py40
-rwxr-xr-xscripts/maintenance/readProbeSetMean_v7.py76
-rwxr-xr-xscripts/maintenance/readProbeSetSE_v7.py508
8 files changed, 342 insertions, 344 deletions
diff --git a/scripts/maintenance/QTL_Reaper_v6.py b/scripts/maintenance/QTL_Reaper_v6.py
index e50dbd40..35f2d1a1 100755
--- a/scripts/maintenance/QTL_Reaper_v6.py
+++ b/scripts/maintenance/QTL_Reaper_v6.py
@@ -7,7 +7,7 @@ import reaper
import MySQLdb
import time
-con = MySQLdb.Connect(db='db_webqtl',user='username',passwd='', host="localhost")
+con = MySQLdb.Connect(db='db_webqtl', user='username', passwd='', host="localhost")
cursor = con.cursor()
genotypeDir = '/gnshare/gn/web/genotypes/'
@@ -23,7 +23,7 @@ for item in results:
ProbeSetFreezeIds=sys.argv[1:]
if ProbeSetFreezeIds:
#####convert the Ids to integer
- ProbeSetFreezeIds=map(int, ProbeSetFreezeIds)
+ ProbeSetFreezeIds=list(map(int, ProbeSetFreezeIds))
else:
#####get all of the dataset that need be updated
@@ -53,7 +53,7 @@ for ProbeSetFreezeId in ProbeSetFreezeIds:
#if InbredSetId==12:
# InbredSetId=2
- print ProbeSetFreezeId, InbredSets[InbredSetId]
+ print((ProbeSetFreezeId, InbredSets[InbredSetId]))
genotype_1.read(InbredSets[InbredSetId])
locuses = []
@@ -102,7 +102,7 @@ for ProbeSetFreezeId in ProbeSetFreezeIds:
kj += 1
if kj%1000==0:
- print ProbeSetFreezeId, InbredSets[InbredSetId],kj
+ print((ProbeSetFreezeId, InbredSets[InbredSetId], kj))
- print ProbeSetFreezeIds
+ print(ProbeSetFreezeIds)
diff --git a/scripts/maintenance/Update_Case_Attributes_MySQL_tab.py b/scripts/maintenance/Update_Case_Attributes_MySQL_tab.py
index 0f8602c9..bf796df4 100644
--- a/scripts/maintenance/Update_Case_Attributes_MySQL_tab.py
+++ b/scripts/maintenance/Update_Case_Attributes_MySQL_tab.py
@@ -24,4 +24,4 @@ for row in csv_data:
#close the connection to the database.
mydb.commit()
cursor.close()
-print "Done" \ No newline at end of file
+print("Done") \ No newline at end of file
diff --git a/scripts/maintenance/delete_genotypes.py b/scripts/maintenance/delete_genotypes.py
index fa693f0f..b7f83758 100755
--- a/scripts/maintenance/delete_genotypes.py
+++ b/scripts/maintenance/delete_genotypes.py
@@ -8,26 +8,26 @@ import genotypes
def main(argv):
# config
config = utilities.get_config(argv[1])
- print "config:"
+ print("config:")
for item in config.items('config'):
- print "\t%s" % (str(item))
+ print(("\t%s" % (str(item))))
# var
- print "variable:"
+ print("variable:")
inbredsetid = config.get('config', 'inbredsetid')
- print "\tinbredsetid: %s" % inbredsetid
+ print(("\tinbredsetid: %s" % inbredsetid))
# datafile
datafile = open(config.get('config', 'datafile'), 'r')
datafile = csv.reader(datafile, delimiter='\t', quotechar='"')
- datafile.next()
+ next(datafile)
delrowcount = 0
for row in datafile:
if len(row) == 0:
continue
genoname = row[0]
delrowcount += genotypes.delete(genoname, inbredsetid)
- print "deleted %d genotypes" % (delrowcount)
+ print(("deleted %d genotypes" % (delrowcount)))
if __name__ == "__main__":
- print "command line arguments:\n\t%s" % sys.argv
+ print(("command line arguments:\n\t%s" % sys.argv))
main(sys.argv)
- print "exit successfully"
+ print("exit successfully")
diff --git a/scripts/maintenance/delete_phenotypes.py b/scripts/maintenance/delete_phenotypes.py
index 326c466e..60dbec61 100755
--- a/scripts/maintenance/delete_phenotypes.py
+++ b/scripts/maintenance/delete_phenotypes.py
@@ -8,13 +8,13 @@ import phenotypes
def main(argv):
# config
config = utilities.get_config(argv[1])
- print "config:"
+ print("config:")
for item in config.items('config'):
- print "\t%s" % (str(item))
+ print(("\t%s" % (str(item))))
# var
- print "variable:"
+ print("variable:")
inbredsetid = config.get('config', 'inbredsetid')
- print "\tinbredsetid: %s" % inbredsetid
+ print(("\tinbredsetid: %s" % inbredsetid))
# datafile
datafile = open(config.get('config', 'datafile'), 'r')
datafile = csv.reader(datafile, delimiter='\t', quotechar='"')
@@ -27,9 +27,9 @@ def main(argv):
except:
continue
delrowcount += phenotypes.delete(publishxrefid=publishxrefid, inbredsetid=inbredsetid)
- print "deleted %d phenotypes" % (delrowcount)
+ print(("deleted %d phenotypes" % (delrowcount)))
if __name__ == "__main__":
- print "command line arguments:\n\t%s" % sys.argv
+ print(("command line arguments:\n\t%s" % sys.argv))
main(sys.argv)
- print "exit successfully"
+ print("exit successfully")
diff --git a/scripts/maintenance/load_genotypes.py b/scripts/maintenance/load_genotypes.py
index 338483f4..51278d48 100755
--- a/scripts/maintenance/load_genotypes.py
+++ b/scripts/maintenance/load_genotypes.py
@@ -8,7 +8,7 @@ def main(argv):
config = utilities.get_config(argv[1])
print("config file:")
for item in config.items('config'):
- print("\t%s" % str(item))
+ print(("\t%s" % str(item)))
parse_genofile(config, fetch_parameters(config))
def fetch_parameters(config):
@@ -19,8 +19,8 @@ def fetch_parameters(config):
config_dic['dataid'] = datastructure.get_nextdataid_genotype()
config_dic['genofile'] = config.get('config', 'genofile')
print("config dictionary:")
- for k, v in config_dic.items():
- print("\t%s: %s" % (k, v))
+ for k, v in list(config_dic.items()):
+ print(("\t%s: %s" % (k, v)))
return config_dic
def parse_genofile(config, config_dic):
@@ -42,10 +42,10 @@ def parse_genofile(config, config_dic):
if line.lower().startswith("chr"):
#
print("geno file meta dictionary:")
- for k, v in meta_dic.items():
- print("\t%s: %s" % (k, v))
+ for k, v in list(meta_dic.items()):
+ print(("\t%s: %s" % (k, v)))
#
- print("geno file head:\n\t%s" % line)
+ print(("geno file head:\n\t%s" % line))
strainnames = line.split()[4:]
config_dic['strains'] = datastructure.get_strains_bynames(inbredsetid=config_dic['inbredsetid'], strainnames=strainnames, updatestrainxref="yes")
continue
@@ -81,7 +81,7 @@ def check_or_insert_geno(config_dic, marker_dic):
result = cursor.fetchone()
if result:
genoid = result[0]
- print("get geno record: %d" % genoid)
+ print(("get geno record: %d" % genoid))
else:
sql = """
INSERT INTO Geno
@@ -95,7 +95,7 @@ def check_or_insert_geno(config_dic, marker_dic):
cursor.execute(sql, (config_dic['speciesid'], marker_dic['locus'], marker_dic['locus'], marker_dic['chromosome'], marker_dic['mb']))
rowcount = cursor.rowcount
genoid = con.insert_id()
- print("INSERT INTO Geno: %d record: %d" % (rowcount, genoid))
+ print(("INSERT INTO Geno: %d record: %d" % (rowcount, genoid)))
return genoid
def check_genoxref(config_dic, marker_dic):
@@ -146,9 +146,9 @@ def insert_genoxref(config_dic, marker_dic):
"""
cursor.execute(sql, (config_dic['genofreezeid'], marker_dic['genoid'], config_dic['dataid'], marker_dic['cm'], 'N'))
rowcount = cursor.rowcount
- print("INSERT INTO GenoXRef: %d record" % (rowcount))
+ print(("INSERT INTO GenoXRef: %d record" % (rowcount)))
if __name__ == "__main__":
- print("command line arguments:\n\t%s" % sys.argv)
+ print(("command line arguments:\n\t%s" % sys.argv))
main(sys.argv)
print("exit successfully")
diff --git a/scripts/maintenance/load_phenotypes.py b/scripts/maintenance/load_phenotypes.py
index c3c6570b..759d2eec 100755
--- a/scripts/maintenance/load_phenotypes.py
+++ b/scripts/maintenance/load_phenotypes.py
@@ -7,37 +7,37 @@ import datastructure
def main(argv):
# config
config = utilities.get_config(argv[1])
- print "config:"
+ print("config:")
for item in config.items('config'):
- print "\t%s" % (str(item))
+ print(("\t%s" % (str(item))))
# var
inbredsetid = config.get('config', 'inbredsetid')
- print "inbredsetid: %s" % inbredsetid
+ print(("inbredsetid: %s" % inbredsetid))
species = datastructure.get_species(inbredsetid)
speciesid = species[0]
- print "speciesid: %s" % speciesid
+ print(("speciesid: %s" % speciesid))
dataid = datastructure.get_nextdataid_phenotype()
- print "next data id: %s" % dataid
+ print(("next data id: %s" % dataid))
cursor, con = utilities.get_cursor()
# datafile
datafile = open(config.get('config', 'datafile'), 'r')
phenotypedata = csv.reader(datafile, delimiter='\t', quotechar='"')
- phenotypedata_head = phenotypedata.next()
- print "phenotypedata head:\n\t%s" % phenotypedata_head
+ phenotypedata_head = next(phenotypedata)
+ print(("phenotypedata head:\n\t%s" % phenotypedata_head))
strainnames = phenotypedata_head[1:]
strains = datastructure.get_strains_bynames(inbredsetid=inbredsetid, strainnames=strainnames, updatestrainxref="yes")
# metafile
metafile = open(config.get('config', 'metafile'), 'r')
phenotypemeta = csv.reader(metafile, delimiter='\t', quotechar='"')
- phenotypemeta_head = phenotypemeta.next()
- print "phenotypemeta head:\n\t%s" % phenotypemeta_head
- print
+ phenotypemeta_head = next(phenotypemeta)
+ print(("phenotypemeta head:\n\t%s" % phenotypemeta_head))
+ print()
# load
for metarow in phenotypemeta:
#
- datarow_value = phenotypedata.next()
- datarow_se = phenotypedata.next()
- datarow_n = phenotypedata.next()
+ datarow_value = next(phenotypedata)
+ datarow_se = next(phenotypedata)
+ datarow_n = next(phenotypedata)
# Phenotype
sql = """
INSERT INTO Phenotype
@@ -67,7 +67,7 @@ def main(argv):
))
rowcount = cursor.rowcount
phenotypeid = con.insert_id()
- print "INSERT INTO Phenotype: %d record: %d" % (rowcount, phenotypeid)
+ print(("INSERT INTO Phenotype: %d record: %d" % (rowcount, phenotypeid)))
# Publication
publicationid = None # reset
pubmed_id = utilities.to_db_string(metarow[0], None)
@@ -81,7 +81,7 @@ def main(argv):
re = cursor.fetchone()
if re:
publicationid = re[0]
- print "get Publication record: %d" % publicationid
+ print(("get Publication record: %d" % publicationid))
if not publicationid:
sql = """
INSERT INTO Publication
@@ -109,7 +109,7 @@ def main(argv):
))
rowcount = cursor.rowcount
publicationid = con.insert_id()
- print "INSERT INTO Publication: %d record: %d" % (rowcount, publicationid)
+ print(("INSERT INTO Publication: %d record: %d" % (rowcount, publicationid)))
# data
for index, strain in enumerate(strains):
#
@@ -158,14 +158,14 @@ def main(argv):
cursor.execute(sql, (inbredsetid, phenotypeid, publicationid, dataid, ""))
rowcount = cursor.rowcount
publishxrefid = con.insert_id()
- print "INSERT INTO PublishXRef: %d record: %d" % (rowcount, publishxrefid)
+ print(("INSERT INTO PublishXRef: %d record: %d" % (rowcount, publishxrefid)))
# for loop next
dataid += 1
- print
+ print()
# release
con.close()
if __name__ == "__main__":
- print "command line arguments:\n\t%s" % sys.argv
+ print(("command line arguments:\n\t%s" % sys.argv))
main(sys.argv)
- print "exit successfully"
+ print("exit successfully")
diff --git a/scripts/maintenance/readProbeSetMean_v7.py b/scripts/maintenance/readProbeSetMean_v7.py
index e9c8f25c..59a51cf9 100755
--- a/scripts/maintenance/readProbeSetMean_v7.py
+++ b/scripts/maintenance/readProbeSetMean_v7.py
@@ -31,20 +31,20 @@ def translateAlias(str):
dataStart = 1
-GeneChipId = int( raw_input("Enter GeneChipId:") )
-ProbeSetFreezeId = int( raw_input("Enter ProbeSetFreezeId:") )
-input_file_name = raw_input("Enter file name with suffix:")
+GeneChipId = int( input("Enter GeneChipId:") )
+ProbeSetFreezeId = int( input("Enter ProbeSetFreezeId:") )
+input_file_name = input("Enter file name with suffix:")
fp = open("%s" % input_file_name, 'rb')
try:
passwd = getpass.getpass('Please enter mysql password here : ')
- con = MySQLdb.Connect(db='db_webqtl',host='localhost', user='username',passwd=passwd)
+ con = MySQLdb.Connect(db='db_webqtl', host='localhost', user='username', passwd=passwd)
db = con.cursor()
- print "You have successfully connected to mysql.\n"
+ print("You have successfully connected to mysql.\n")
except:
- print "You entered incorrect password.\n"
+ print("You entered incorrect password.\n")
sys.exit(0)
time0 = time.time()
@@ -55,22 +55,22 @@ time0 = time.time()
# generate the gene list of expression data here
#
#########################################################################
-print 'Checking if each line have same number of members'
+print('Checking if each line have same number of members')
GeneList = []
isCont = 1
header = fp.readline()
-header = string.split(string.strip(header),'\t')
-header = map(string.strip, header)
+header = string.split(string.strip(header), '\t')
+header = list(map(string.strip, header))
nfield = len(header)
line = fp.readline()
kj=0
while line:
- line2 = string.split(string.strip(line),'\t')
- line2 = map(string.strip, line2)
+ line2 = string.split(string.strip(line), '\t')
+ line2 = list(map(string.strip, line2))
if len(line2) != nfield:
- print "Error : " + line
+ print(("Error : " + line))
isCont = 0
GeneList.append(line2[0])
@@ -78,30 +78,29 @@ while line:
kj+=1
if kj%100000 == 0:
- print 'checked ',kj,' lines'
+ print(('checked ', kj, ' lines'))
-GeneList = map(string.lower, GeneList)
-GeneList.sort()
+GeneList = sorted(map(string.lower, GeneList))
if isCont==0:
sys.exit(0)
-print 'used ',time.time()-time0,' seconds'
+print(('used ', time.time()-time0, ' seconds'))
#########################################################################
#
# Check if each strain exist in database
# generate the string id list of expression data here
#
#########################################################################
-print 'Checking if each strain exist in database'
+print('Checking if each strain exist in database')
isCont = 1
fp.seek(0)
header = fp.readline()
-header = string.split(string.strip(header),'\t')
-header = map(string.strip, header)
-header = map(translateAlias, header)
+header = string.split(string.strip(header), '\t')
+header = list(map(string.strip, header))
+header = list(map(translateAlias, header))
header = header[dataStart:]
Ids = []
for item in header:
@@ -109,26 +108,26 @@ for item in header:
db.execute('select Id from Strain where Name = "%s"' % item)
Ids.append(db.fetchall()[0][0])
except:
- print item,'does not exist, check the if the strain name is correct'
+ print((item, 'does not exist, check the if the strain name is correct'))
isCont=0
if isCont==0:
sys.exit(0)
-print 'used ',time.time()-time0,' seconds'
+print(('used ', time.time()-time0, ' seconds'))
########################################################################
#
# Check if each ProbeSet exist in database
#
########################################################################
-print 'Check if each ProbeSet exist in database'
+print('Check if each ProbeSet exist in database')
##---- find PID is name or target ----##
line = fp.readline()
line = fp.readline()
-line2 = string.split(string.strip(line),'\t')
-line2 = map(string.strip, line2)
+line2 = string.split(string.strip(line), '\t')
+line2 = list(map(string.strip, line2))
PId = line2[0]
db.execute('select Id from ProbeSet where Name="%s" and ChipId=%d' % (PId, GeneChipId) )
@@ -146,11 +145,10 @@ Names = []
for item in results:
Names.append(item[0])
-print Names
+print(Names)
-Names = map(string.lower, Names)
+Names = sorted(map(string.lower, Names))
-Names.sort() # -- Fixed the lower case problem of ProbeSets affx-mur_b2_at doesn't exist --#
##---- compare genelist with names ----##
@@ -170,7 +168,7 @@ while x<len(GeneList) and y<len(Names):
y += 1
if x%100000==0:
- print 'check Name, checked %d lines'%x
+ print(('check Name, checked %d lines'%x))
while x<len(GeneList):
GeneList2.append(GeneList[x])
@@ -180,20 +178,20 @@ isCont=1
ferror = open("ProbeSetError.txt", "wb")
for item in GeneList2:
ferror.write(item + " doesn't exist \n")
- print item, " doesn't exist, check if the ProbeSet name is correct"
+ print((item, " doesn't exist, check if the ProbeSet name is correct"))
isCont = 0
if isCont==0:
sys.exit(0)
-print 'used ',time.time()-time0,' seconds'
+print(('used ', time.time()-time0, ' seconds'))
#########################################################################
#
# Insert data into database
#
#########################################################################
-print 'getting ProbeSet/Id'
+print('getting ProbeSet/Id')
#---- get Name/Id map ----#
@@ -202,16 +200,16 @@ results = db.fetchall()
NameIds = {}
for item in results:
NameIds[item[0]] = item[1]
-print 'used ',time.time()-time0,' seconds'
+print(('used ', time.time()-time0, ' seconds'))
-print 'inserting data'
+print('inserting data')
##---- get old max dataId ----##
db.execute('select max(Id) from ProbeSetData')
maxDataId = int(db.fetchall()[0][0])
bmax = maxDataId
-print "old_max = %d\n" % bmax
+print(("old_max = %d\n" % bmax))
##---- insert data ----##
fp.seek(0)
@@ -222,8 +220,8 @@ kj = 0
values1 = []
values2 = []
while line:
- line2 = string.split(string.strip(line),'\t')
- line2 = map(string.strip, line2)
+ line2 = string.split(string.strip(line), '\t')
+ line2 = list(map(string.strip, line2))
PId = line2[0]
recordId = NameIds[PId]
@@ -255,8 +253,8 @@ while line:
values1=[]
values2=[]
- print 'Inserted ', kj,' lines'
- print 'used ',time.time()-time0,' seconds'
+ print(('Inserted ', kj, ' lines'))
+ print(('used ', time.time()-time0, ' seconds'))
line = fp.readline()
diff --git a/scripts/maintenance/readProbeSetSE_v7.py b/scripts/maintenance/readProbeSetSE_v7.py
index fd6f0bb8..20a846a4 100755
--- a/scripts/maintenance/readProbeSetSE_v7.py
+++ b/scripts/maintenance/readProbeSetSE_v7.py
@@ -1,254 +1,254 @@
-#!/usr/bin/python2
-"""This script use the nearest marker to the transcript as control, increasing permutation rounds according to the p-value"""
-########################################################################
-# Last Updated Sep 27, 2011 by Xiaodong
-# This version fix the bug that incorrectly exclude the first 2 probesetIDs
-########################################################################
-
-import string
-import sys
-import MySQLdb
-import getpass
-import time
-
-
-def translateAlias(str):
- if str == "B6":
- return "C57BL/6J"
- elif str == "D2":
- return "DBA/2J"
- else:
- return str
-
-########################################################################
-#
-# Indicate Data Start Position, ProbeFreezeId, GeneChipId, DataFile
-#
-########################################################################
-
-dataStart = 1
-
-GeneChipId = int( raw_input("Enter GeneChipId:") )
-ProbeSetFreezeId = int( raw_input("Enter ProbeSetFreezeId:") )
-input_file_name = raw_input("Enter file name with suffix:")
-
-fp = open("%s" % input_file_name, 'rb')
-
-
-try:
- passwd = getpass.getpass('Please enter mysql password here : ')
- con = MySQLdb.Connect(db='db_webqtl',host='localhost', user='username',passwd=passwd)
-
- db = con.cursor()
- print "You have successfully connected to mysql.\n"
-except:
- print "You entered incorrect password.\n"
- sys.exit(0)
-
-time0 = time.time()
-########################################################################
-#
-# Indicate Data Start Position, ProbeFreezeId, GeneChipId, DataFile
-#
-########################################################################
-
-#GeneChipId = 4
-#dataStart = 1
-#ProbeSetFreezeId = 359 #JAX Liver 6C Affy M430 2.0 (Jul11) MDP
-#fp = open("GSE10493_AllSamples_6C_Z_AvgSE.txt", 'rb')
-
-
-#########################################################################
-#
-# Check if each line have same number of members
-# generate the gene list of expression data here
-#
-#########################################################################
-print 'Checking if each line have same number of members'
-
-GeneList = []
-isCont = 1
-header = fp.readline()
-header = string.split(string.strip(header),'\t')
-header = map(string.strip, header)
-nfield = len(header)
-line = fp.readline()
-
-kj=0
-while line:
- line2 = string.split(string.strip(line),'\t')
- line2 = map(string.strip, line2)
- if len(line2) != nfield:
- print "Error : " + line
- isCont = 0
-
- GeneList.append(line2[0])
- line = fp.readline()
-
- kj+=1
- if kj%100000 == 0:
- print 'checked ',kj,' lines'
-
-GeneList = map(string.lower, GeneList)
-GeneList.sort()
-
-if isCont==0:
- sys.exit(0)
-
-
-print 'used ',time.time()-time0,' seconds'
-#########################################################################
-#
-# Check if each strain exist in database
-# generate the string id list of expression data here
-#
-#########################################################################
-print 'Checking if each strain exist in database'
-
-isCont = 1
-fp.seek(0)
-header = fp.readline()
-header = string.split(string.strip(header),'\t')
-header = map(string.strip, header)
-header = map(translateAlias, header)
-header = header[dataStart:]
-Ids = []
-for item in header:
- try:
- db.execute('select Id from Strain where Name = "%s"' % item)
- Ids.append(db.fetchall()[0][0])
- except:
- print item,'does not exist, check the if the strain name is correct'
- isCont=0
-
-if isCont==0:
- sys.exit(0)
-
-
-print 'used ',time.time()-time0,' seconds'
-########################################################################
-#
-# Check if each ProbeSet exist in database
-#
-########################################################################
-print 'Check if each ProbeSet exist in database'
-
-##---- find PID is name or target ----##
-line = fp.readline()
-line = fp.readline()
-line2 = string.split(string.strip(line),'\t')
-line2 = map(string.strip, line2)
-PId = line2[0]
-
-db.execute('select Id from ProbeSet where Name="%s" and ChipId=%d' % (PId, GeneChipId))
-results = db.fetchall()
-IdStr = 'TargetId'
-if len(results)>0:
- IdStr = 'Name'
-
-
-##---- get Name/TargetId list from database ----##
-db.execute('select distinct(%s) from ProbeSet where ChipId=%d order by %s' % (IdStr, GeneChipId, IdStr))
-results = db.fetchall()
-
-Names = []
-for item in results:
- Names.append(item[0])
-Names = map(string.lower, Names)
-Names.sort() # -- Fixed the lower case problem of ProbeSets affx-mur_b2_at doesn't exist --#
-
-##---- compare genelist with names ----##
-x=y=0
-x1=-1
-GeneList2=[]
-while x<len(GeneList) and y<len(Names):
- if GeneList[x]==Names[y]:
- x += 1
- y += 1
- elif GeneList[x]<Names[y]:
- if x!=x1:
- GeneList2.append(GeneList[x])
- x1 = x
- x += 1
- elif GeneList[x]>Names[y]:
- y += 1
-
- if x%100000==0:
- print 'check Name, checked %d lines'%x
-
-while x<len(GeneList):
- GeneList2.append(GeneList[x])
- x += 1
-
-isCont=1
-ferror = open("ProbeSetError.txt", "wb")
-for item in GeneList2:
- ferror.write(item + " doesn't exist \n")
- print item, " doesn't exist"
- isCont = 0
-
-if isCont==0:
- sys.exit(0)
-
-
-print 'used ',time.time()-time0,' seconds'
-#############################
-#Insert new Data into SE
-############################
-db.execute("""
- select ProbeSet.%s, ProbeSetXRef.DataId from ProbeSet, ProbeSetXRef
- where ProbeSet.Id=ProbeSetXRef.ProbeSetId and ProbeSetXRef.ProbeSetFreezeId=%d"""
- % (IdStr, ProbeSetFreezeId))
-results = db.fetchall()
-
-ProbeNameId = {}
-for Name, Id in results:
- ProbeNameId[Name] = Id
-
-ferror = open("ProbeError.txt", "wb")
-
-DataValues = []
-
-fp.seek(0) #XZ add this line
-line = fp.readline() #XZ add this line
-line = fp.readline()
-
-kj = 0
-while line:
- line2 = string.split(string.strip(line),'\t')
- line2 = map(string.strip, line2)
-
- CellId = line2[0]
- if not ProbeNameId.has_key(CellId):
- ferror.write(CellId + " doesn't exist\n")
- print CellId, " doesn't exist"
- else:
- DataId = ProbeNameId[CellId]
- datasorig = line2[dataStart:]
-
- i = 0
- for item in datasorig:
- if item != '':
- value = '('+str(DataId)+','+str(Ids[i])+','+str(item)+')'
- DataValues.append(value)
- i += 1
-
- kj += 1
- if kj % 100 == 0:
- Dataitems = ','.join(DataValues)
- cmd = 'insert ProbeSetSE values %s' % Dataitems
- db.execute(cmd)
-
- DataValues = []
- print 'inserted ',kj,' lines'
- print 'used ',time.time()-time0,' seconds'
- line = fp.readline()
-
-if len(DataValues)>0:
- DataValues = ','.join(DataValues)
- cmd = 'insert ProbeSetSE values %s' % DataValues
- db.execute(cmd)
-
-con.close()
-
-
+#!/usr/bin/python2
+"""This script use the nearest marker to the transcript as control, increasing permutation rounds according to the p-value"""
+########################################################################
+# Last Updated Sep 27, 2011 by Xiaodong
+# This version fix the bug that incorrectly exclude the first 2 probesetIDs
+########################################################################
+
+import string
+import sys
+import MySQLdb
+import getpass
+import time
+
+
+def translateAlias(str):
+ if str == "B6":
+ return "C57BL/6J"
+ elif str == "D2":
+ return "DBA/2J"
+ else:
+ return str
+
+########################################################################
+#
+# Indicate Data Start Position, ProbeFreezeId, GeneChipId, DataFile
+#
+########################################################################
+
+
+dataStart = 1
+
+GeneChipId = int(input("Enter GeneChipId:"))
+ProbeSetFreezeId = int(input("Enter ProbeSetFreezeId:"))
+input_file_name = input("Enter file name with suffix:")
+
+fp = open("%s" % input_file_name, 'rb')
+
+
+try:
+ passwd = getpass.getpass('Please enter mysql password here : ')
+ con = MySQLdb.Connect(db='db_webqtl', host='localhost',
+ user='username', passwd=passwd)
+
+ db = con.cursor()
+ print("You have successfully connected to mysql.\n")
+except:
+ print("You entered incorrect password.\n")
+ sys.exit(0)
+
+time0 = time.time()
+########################################################################
+#
+# Indicate Data Start Position, ProbeFreezeId, GeneChipId, DataFile
+#
+########################################################################
+
+#GeneChipId = 4
+#dataStart = 1
+# ProbeSetFreezeId = 359 #JAX Liver 6C Affy M430 2.0 (Jul11) MDP
+#fp = open("GSE10493_AllSamples_6C_Z_AvgSE.txt", 'rb')
+
+
+#########################################################################
+#
+# Check if each line have same number of members
+# generate the gene list of expression data here
+#
+#########################################################################
+print('Checking if each line have same number of members')
+
+GeneList = []
+isCont = 1
+header = fp.readline()
+header = string.split(string.strip(header), '\t')
+header = list(map(string.strip, header))
+nfield = len(header)
+line = fp.readline()
+
+kj = 0
+while line:
+ line2 = string.split(string.strip(line), '\t')
+ line2 = list(map(string.strip, line2))
+ if len(line2) != nfield:
+ isCont = 0
+ print(("Error : " + line))
+
+ GeneList.append(line2[0])
+ line = fp.readline()
+
+ kj += 1
+ if kj % 100000 == 0:
+ print(('checked ', kj, ' lines'))
+
+GeneList = sorted(map(string.lower, GeneList))
+
+if isCont == 0:
+ sys.exit(0)
+
+
+print(('used ', time.time()-time0, ' seconds'))
+#########################################################################
+#
+# Check if each strain exist in database
+# generate the string id list of expression data here
+#
+#########################################################################
+print('Checking if each strain exist in database')
+
+isCont = 1
+fp.seek(0)
+header = fp.readline()
+header = string.split(string.strip(header), '\t')
+header = list(map(string.strip, header))
+header = list(map(translateAlias, header))
+header = header[dataStart:]
+Ids = []
+for item in header:
+ try:
+ db.execute('select Id from Strain where Name = "%s"' % item)
+ Ids.append(db.fetchall()[0][0])
+ except:
+ isCont = 0
+ print((item, 'does not exist, check the if the strain name is correct'))
+
+if isCont == 0:
+ sys.exit(0)
+
+
+print(('used ', time.time()-time0, ' seconds'))
+########################################################################
+#
+# Check if each ProbeSet exist in database
+#
+########################################################################
+print('Check if each ProbeSet exist in database')
+
+##---- find PID is name or target ----##
+line = fp.readline()
+line = fp.readline()
+line2 = string.split(string.strip(line), '\t')
+line2 = list(map(string.strip, line2))
+PId = line2[0]
+
+db.execute('select Id from ProbeSet where Name="%s" and ChipId=%d' %
+ (PId, GeneChipId))
+results = db.fetchall()
+IdStr = 'TargetId'
+if len(results) > 0:
+ IdStr = 'Name'
+
+
+##---- get Name/TargetId list from database ----##
+db.execute('select distinct(%s) from ProbeSet where ChipId=%d order by %s' % (
+ IdStr, GeneChipId, IdStr))
+results = db.fetchall()
+
+Names = []
+for item in results:
+ Names.append(item[0])
+ Names = sorted(map(string.lower, Names))
+
+##---- compare genelist with names ----##
+x = y = 0
+x1 = -1
+GeneList2 = []
+while x < len(GeneList) and y < len(Names):
+ if GeneList[x] == Names[y]:
+ x += 1
+ y += 1
+ elif GeneList[x] < Names[y]:
+ if x != x1:
+ GeneList2.append(GeneList[x])
+ x1 = x
+ x += 1
+ elif GeneList[x] > Names[y]:
+ y += 1
+
+ if x % 100000 == 0:
+ print(('check Name, checked %d lines' % x))
+
+while x < len(GeneList):
+ GeneList2.append(GeneList[x])
+ x += 1
+
+isCont = 1
+ferror = open("ProbeSetError.txt", "wb")
+for item in GeneList2:
+ ferror.write(item + " doesn't exist \n")
+ isCont = 0
+
+ print((item, " doesn't exist"))
+if isCont == 0:
+ sys.exit(0)
+
+
+print(('used ', time.time()-time0, ' seconds'))
+#############################
+# Insert new Data into SE
+############################
+db.execute("""
+ select ProbeSet.%s, ProbeSetXRef.DataId from ProbeSet, ProbeSetXRef
+ where ProbeSet.Id=ProbeSetXRef.ProbeSetId and ProbeSetXRef.ProbeSetFreezeId=%d"""
+ % (IdStr, ProbeSetFreezeId))
+results = db.fetchall()
+
+ProbeNameId = {}
+for Name, Id in results:
+ ProbeNameId[Name] = Id
+
+ferror = open("ProbeError.txt", "wb")
+
+DataValues = []
+
+fp.seek(0) # XZ add this line
+line = fp.readline() # XZ add this line
+line = fp.readline()
+
+kj = 0
+while line:
+ line2 = string.split(string.strip(line), '\t')
+ line2 = list(map(string.strip, line2))
+
+ CellId = line2[0]
+ if CellId not in ProbeNameId:
+ ferror.write(CellId + " doesn't exist\n")
+ else:
+ DataId = ProbeNameId[CellId]
+ datasorig = line2[dataStart:]
+
+ i = 0
+ for item in datasorig:
+ if item != '':
+ value = '('+str(DataId)+','+str(Ids[i])+','+str(item)+')'
+ DataValues.append(value)
+ i += 1
+
+ kj += 1
+ if kj % 100 == 0:
+ Dataitems = ','.join(DataValues)
+ cmd = 'insert ProbeSetSE values %s' % Dataitems
+ db.execute(cmd)
+
+ DataValues = []
+ line = fp.readline()
+ print((CellId, " doesn't exist"))
+ print(('inserted ', kj, ' lines'))
+ print(('used ', time.time()-time0, ' seconds'))
+
+if len(DataValues) > 0:
+ DataValues = ','.join(DataValues)
+ cmd = 'insert ProbeSetSE values %s' % DataValues
+ db.execute(cmd)
+
+con.close()
generated by cgit v1.2.3 (git 2.44.0) at 2024-11-29 15:05:36 +0000