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authorzsloan2021-05-06 18:07:19 -0500
committerGitHub2021-05-06 18:07:19 -0500
commit9ed3c226c561d80957e34294f884fe48373cf6e6 (patch)
tree7b3c603b961aa4b840d82ef289887b0a31c0f676 /wqflask/utility/gen_geno_ob.py
parent2444d60a93ef7c9900ed9a52877bff0ee08fbfb6 (diff)
parent3c430082b767a29c3e35cb03e68c1b22373ad353 (diff)
downloadgenenetwork2-9ed3c226c561d80957e34294f884fe48373cf6e6.tar.gz
Merge branch 'testing' into bug/fix_rqtl_covariates
Diffstat (limited to 'wqflask/utility/gen_geno_ob.py')
-rw-r--r--wqflask/utility/gen_geno_ob.py35
1 files changed, 21 insertions, 14 deletions
diff --git a/wqflask/utility/gen_geno_ob.py b/wqflask/utility/gen_geno_ob.py
index 81085ffe..e619b7b6 100644
--- a/wqflask/utility/gen_geno_ob.py
+++ b/wqflask/utility/gen_geno_ob.py
@@ -1,7 +1,8 @@
import utility.logger
-logger = utility.logger.getLogger(__name__ )
+logger = utility.logger.getLogger(__name__)
-class genotype(object):
+
+class genotype:
"""
Replacement for reaper.Dataset so we can remove qtlreaper use while still generating mapping output figure
"""
@@ -18,7 +19,7 @@ class genotype(object):
self.filler = False
self.mb_exists = False
- #ZS: This is because I'm not sure if some files switch the column that contains Mb/cM positions; might be unnecessary
+ # ZS: This is because I'm not sure if some files switch the column that contains Mb/cM positions; might be unnecessary
self.cm_column = 2
self.mb_column = 3
@@ -36,14 +37,16 @@ class genotype(object):
return len(self.chromosomes)
def read_rdata_output(self, qtl_results):
- #ZS: This is necessary because R/qtl requires centimorgan marker positions, which it normally gets from the .geno file, but that doesn't exist for HET3-ITP (which only has RData), so it needs to read in the marker cM positions from the results
- self.chromosomes = [] #ZS: Overwriting since the .geno file's contents are just placeholders
+ # ZS: This is necessary because R/qtl requires centimorgan marker positions, which it normally gets from the .geno file, but that doesn't exist for HET3-ITP (which only has RData), so it needs to read in the marker cM positions from the results
+ # ZS: Overwriting since the .geno file's contents are just placeholders
+ self.chromosomes = []
- this_chr = "" #ZS: This is so it can track when the chromosome changes as it iterates through markers
+ this_chr = "" # ZS: This is so it can track when the chromosome changes as it iterates through markers
chr_ob = None
for marker in qtl_results:
locus = Locus(self)
- if (str(marker['chr']) != this_chr) and this_chr != "X": #ZS: This is really awkward but works as a temporary fix
+ # ZS: This is really awkward but works as a temporary fix
+ if (str(marker['chr']) != this_chr) and this_chr != "X":
if this_chr != "":
self.chromosomes.append(chr_ob)
this_chr = str(marker['chr'])
@@ -68,7 +71,7 @@ class genotype(object):
with open(filename, 'r') as geno_file:
lines = geno_file.readlines()
- this_chr = "" #ZS: This is so it can track when the chromosome changes as it iterates through markers
+ this_chr = "" # ZS: This is so it can track when the chromosome changes as it iterates through markers
chr_ob = None
for line in lines:
if line[0] == "#":
@@ -119,7 +122,8 @@ class genotype(object):
self.chromosomes.append(chr_ob)
-class Chr(object):
+
+class Chr:
def __init__(self, name, geno_ob):
self.name = name
self.loci = []
@@ -140,8 +144,9 @@ class Chr(object):
def add_marker(self, marker_row):
self.loci.append(Locus(self.geno_ob, marker_row))
-class Locus(object):
- def __init__(self, geno_ob, marker_row = None):
+
+class Locus:
+ def __init__(self, geno_ob, marker_row=None):
self.chr = None
self.name = None
self.cM = None
@@ -153,9 +158,11 @@ class Locus(object):
try:
self.cM = float(marker_row[geno_ob.cm_column])
except:
- self.cM = float(marker_row[geno_ob.mb_column]) if geno_ob.mb_exists else 0
+ self.cM = float(
+ marker_row[geno_ob.mb_column]) if geno_ob.mb_exists else 0
try:
- self.Mb = float(marker_row[geno_ob.mb_column]) if geno_ob.mb_exists else None
+ self.Mb = float(
+ marker_row[geno_ob.mb_column]) if geno_ob.mb_exists else None
except:
self.Mb = self.cM
@@ -175,5 +182,5 @@ class Locus(object):
for allele in marker_row[start_pos:]:
if allele in list(geno_table.keys()):
self.genotype.append(geno_table[allele])
- else: #ZS: Some genotype appears that isn't specified in the metadata, make it unknown
+ else: # ZS: Some genotype appears that isn't specified in the metadata, make it unknown
self.genotype.append("U")