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authorFrederick Muriuki Muriithi2024-10-29 12:59:54 -0500
committerFrederick Muriuki Muriithi2024-10-29 12:59:54 -0500
commitd2219521f39cad50655384d079573e1428f3c0ff (patch)
tree04139b084bd37c9bb6a62f694f7815788d9c558d
parentd28391bc9d1ad806765462c73b3c6aa37f74d519 (diff)
downloadgenenetwork2-d2219521f39cad50655384d079573e1428f3c0ff.tar.gz
Change indentation, wrap code in function and create entry-point.
-rwxr-xr-xscripts/maintenance/QTL_Reaper_v6.py207
1 files changed, 105 insertions, 102 deletions
diff --git a/scripts/maintenance/QTL_Reaper_v6.py b/scripts/maintenance/QTL_Reaper_v6.py
index 20fd8e3b..cfbf31bb 100755
--- a/scripts/maintenance/QTL_Reaper_v6.py
+++ b/scripts/maintenance/QTL_Reaper_v6.py
@@ -7,105 +7,108 @@ import reaper
import MySQLdb
import time
-con = MySQLdb.Connect(db='db_webqtl', user='username', passwd='', host="localhost")
-cursor = con.cursor()
-
-genotypeDir = '/gnshare/gn/web/genotypes/'
-genotype_1 = reaper.Dataset()
-
-#####get all of the genotypes
-cursor.execute('select Id, Name from InbredSet')
-results = cursor.fetchall()
-InbredSets = {}
-for item in results:
- InbredSets[item[0]] = genotypeDir+str(item[1])+'.geno'
-
-ProbeSetFreezeIds=sys.argv[1:]
-if ProbeSetFreezeIds:
- #####convert the Ids to integer
- ProbeSetFreezeIds=list(map(int, ProbeSetFreezeIds))
-
-else:
- #####get all of the dataset that need be updated
- cursor.execute('select distinct(ProbeSetFreezeId) from ProbeSetXRef where pValue is NULL order by ProbeSetFreezeId desc')
- results = cursor.fetchall()
- ProbeSetFreezeIds = []
- for item in results:
- ProbeSetFreezeIds.append(item[0])
-
-####human dataset can NOT use this program calculate the LRS, ignore it
-if ProbeSetFreezeIds.__contains__(215):
- ProbeSetFreezeIds.remove(215)
-
-#output_file = open ('/home/xzhou/work/DatabaseTools/cal_LRS_Additive_result.txt', 'w')
-
-#####update
-for ProbeSetFreezeId in ProbeSetFreezeIds:
- cursor.execute("""
- select InbredSetId
- from ProbeFreeze, ProbeSetFreeze
- where ProbeFreeze.Id=ProbeSetFreeze.ProbeFreezeId and ProbeSetFreeze.Id=%d
- """%ProbeSetFreezeId);
-
- InbredSetId = cursor.fetchone()[0]
- if InbredSetId==3:
- InbredSetId=1
- #if InbredSetId==12:
- # InbredSetId=2
-
- print((ProbeSetFreezeId, InbredSets[InbredSetId]))
-
- genotype_1.read(InbredSets[InbredSetId])
- locuses = []
- for geno in genotype_1:
- for locus in geno:
- locuses.append(locus.name)
-
- cursor.execute('select ProbeSetId, Locus, DataId from ProbeSetXRef where ProbeSetFreezeId=%s'%ProbeSetFreezeId)
- ProbeSetXRefInfos = cursor.fetchall()
-
- kj=0
- for aProbeSetXRef in ProbeSetXRefInfos:
- ProbeSetId, Locus, DataId = aProbeSetXRef
- prgy = genotype_1.prgy
-
- cursor.execute("select Strain.Name, ProbeSetData.value from Strain, ProbeSetData where Strain.Id = ProbeSetData.StrainId and ProbeSetData.Id = %d" % DataId)
- results = cursor.fetchall()
- if not results:
- continue
- _strains = []
- _values = []
- for item2 in results:
- strain, value = item2
- if strain in prgy:
- _strains.append(strain)
- _values.append(value)
- if not _strains or not _values:
- continue
-
- if len(_strains) < 8:
- continue
- qtlresults = genotype_1.regression(strains = _strains, trait = _values)
- _max = max(qtlresults)
- _locus = _max.locus.name
- _additive = _max.additive
- _max = _max.lrs
-
- #output_file.write('%s\t%s\t%s\t%s\t%s\n' % (ProbeSetFreezeId, ProbeSetId, _locus, _max, _additive))
-
- # _max(LRS) maybe is infinite sometimes, so define it as a very big number
- if _max == float('inf'):
- _max = 10000
-
- cursor.execute('update ProbeSetXRef set Locus=%s, LRS=%s, additive=%s where ProbeSetId=%s and ProbeSetFreezeId=%s', \
- (_locus, _max, _additive, ProbeSetId, ProbeSetFreezeId))
-
- kj += 1
- if kj%1000==0:
- print((ProbeSetFreezeId, InbredSets[InbredSetId], kj))
-
-
- print(ProbeSetFreezeIds)
-
-cursor.close()
-con.close()
+
+def run_qtl_reaper(cursor, genotypeDir):
+ genotype_1 = reaper.Dataset()
+ #####get all of the genotypes
+ cursor.execute('select Id, Name from InbredSet')
+ results = cursor.fetchall()
+ InbredSets = {}
+ for item in results:
+ InbredSets[item[0]] = genotypeDir+str(item[1])+'.geno'
+
+ ProbeSetFreezeIds=sys.argv[1:]
+ if ProbeSetFreezeIds:
+ #####convert the Ids to integer
+ ProbeSetFreezeIds=list(map(int, ProbeSetFreezeIds))
+ else:
+ #####get all of the dataset that need be updated
+ cursor.execute('select distinct(ProbeSetFreezeId) from ProbeSetXRef where pValue is NULL order by ProbeSetFreezeId desc')
+ results = cursor.fetchall()
+ ProbeSetFreezeIds = []
+ for item in results:
+ ProbeSetFreezeIds.append(item[0])
+
+ ####human dataset can NOT use this program calculate the LRS, ignore it
+ if ProbeSetFreezeIds.__contains__(215):
+ ProbeSetFreezeIds.remove(215)
+
+ #output_file = open ('/home/xzhou/work/DatabaseTools/cal_LRS_Additive_result.txt', 'w')
+
+ #####update
+ for ProbeSetFreezeId in ProbeSetFreezeIds:
+ cursor.execute("""
+ select InbredSetId
+ from ProbeFreeze, ProbeSetFreeze
+ where ProbeFreeze.Id=ProbeSetFreeze.ProbeFreezeId and ProbeSetFreeze.Id=%d
+ """%ProbeSetFreezeId);
+
+ InbredSetId = cursor.fetchone()[0]
+ if InbredSetId==3:
+ InbredSetId=1
+ #if InbredSetId==12:
+ # InbredSetId=2
+
+ print((ProbeSetFreezeId, InbredSets[InbredSetId]))
+
+ genotype_1.read(InbredSets[InbredSetId])
+ locuses = []
+ for geno in genotype_1:
+ for locus in geno:
+ locuses.append(locus.name)
+
+ cursor.execute('select ProbeSetId, Locus, DataId from ProbeSetXRef where ProbeSetFreezeId=%s'%ProbeSetFreezeId)
+ ProbeSetXRefInfos = cursor.fetchall()
+
+ kj=0
+ for aProbeSetXRef in ProbeSetXRefInfos:
+ ProbeSetId, Locus, DataId = aProbeSetXRef
+ prgy = genotype_1.prgy
+
+ cursor.execute("select Strain.Name, ProbeSetData.value from Strain, ProbeSetData where Strain.Id = ProbeSetData.StrainId and ProbeSetData.Id = %d" % DataId)
+ results = cursor.fetchall()
+ if not results:
+ continue
+ _strains = []
+ _values = []
+ for item2 in results:
+ strain, value = item2
+ if strain in prgy:
+ _strains.append(strain)
+ _values.append(value)
+ if not _strains or not _values:
+ continue
+
+ if len(_strains) < 8:
+ continue
+ qtlresults = genotype_1.regression(strains = _strains, trait = _values)
+ _max = max(qtlresults)
+ _locus = _max.locus.name
+ _additive = _max.additive
+ _max = _max.lrs
+
+ #output_file.write('%s\t%s\t%s\t%s\t%s\n' % (ProbeSetFreezeId, ProbeSetId, _locus, _max, _additive))
+
+ # _max(LRS) maybe is infinite sometimes, so define it as a very big number
+ if _max == float('inf'):
+ _max = 10000
+
+ cursor.execute('update ProbeSetXRef set Locus=%s, LRS=%s, additive=%s where ProbeSetId=%s and ProbeSetFreezeId=%s',
+ (_locus, _max, _additive, ProbeSetId, ProbeSetFreezeId))
+
+ kj += 1
+ if kj%1000==0:
+ print((ProbeSetFreezeId, InbredSets[InbredSetId], kj))
+
+
+ print(ProbeSetFreezeIds)
+
+ cursor.close()
+
+def main():
+ con = MySQLdb.Connect(db='db_webqtl', user='username', passwd='', host="localhost")
+ run_qtl_reaper(con.cursor(), "/gnshare/gn/web/genotypes/")
+ con.close()
+
+if __name__ == "__main__":
+ main()