diff options
| -rw-r--r-- | ratspub_keywords.py | 2 | ||||
| -rw-r--r-- | static/ratspub.png | bin | 258462 -> 298585 bytes | |||
| -rw-r--r-- | templates/about.html | 3 | ||||
| -rw-r--r-- | templates/index.html | 16 | ||||
| -rw-r--r-- | topGene_symb_alias.txt | 200 |
5 files changed, 211 insertions, 10 deletions
diff --git a/ratspub_keywords.py b/ratspub_keywords.py index 0c7d0dd..8a23e73 100644 --- a/ratspub_keywords.py +++ b/ratspub_keywords.py @@ -1,7 +1,7 @@ addiction_d = {"reward":"reward|hedonic|incentive|intracranial self stimulation|ICSS|reinforcement|reinforcing|conditioned place preference|CPP|self administration|self administered|drug reinforced|operant|instrumental response", "aversion":"aversion|aversive|CTA|conditioned taste aversion", "withdrawal":"withdrawal", - "relapse":"relapse|reinstatement|craving|drug seeking|seeking|incubation", + "relapse":"relapse|reinstatement|craving|drug seeking|seeking", "sensitization":"sensitization", "addiction":"addiction|addictive|drug abuse|punishment|compulsive|escalation", "dependence":"dependence", diff --git a/static/ratspub.png b/static/ratspub.png Binary files differindex a031bc0..9fa0a49 100644 --- a/static/ratspub.png +++ b/static/ratspub.png diff --git a/templates/about.html b/templates/about.html index 4d944e9..ebd8554 100644 --- a/templates/about.html +++ b/templates/about.html @@ -2,7 +2,8 @@ {% extends "layout.html" %} {% block content %} -<h3> About RatsPub ...</h3> +<h3> About RatsPub </h3> +<hr> <p>RatsPub searches PubMed to find abstracts containing genes of interest and a list of curated addiction-related keywords. The abstracts corresponding to these returned PMIDs are then retrieve from a <a href="https://dataguide.nlm.nih.gov/edirect/archive.html">local archive of the PubMed</a>. No limit on the date of publication is set. Each abstract is then broken down into sentences, which are then filtered by gene names and keywords. diff --git a/templates/index.html b/templates/index.html index 7df2a4e..f9a4fc1 100644 --- a/templates/index.html +++ b/templates/index.html @@ -7,21 +7,21 @@ <table> <tr><td > -<p> - RatsPub searches PubMed to find <i>sentences</i> that contain the query terms (i.e., gene symbols) and <a href="https://github.com/chen42/RatsPub/blob/master/ratspub_keywords.py">drug addiction-related keywords</a>. These gene-keyword relationships are presented as an interactive graph that can efficiently answer the question <b>"What do we know about these genes and addiction?". </b> Data from <a href="https://www.ebi.ac.uk/gwas/">EBI GWAS catalog </a>are also included in the search to better answer this question. + +<p> RatsPub searches PubMed to find <i>sentences</i> that contain the query terms (i.e., gene symbols) and <a href="https://github.com/chen42/RatsPub/blob/master/ratspub_keywords.py">drug addiction-related keywords</a>. These gene-keyword relationships are presented as an interactive graph that can efficiently answer the question <b>"What do we know about these genes and addiction?". </b> Data from <a href="https://www.ebi.ac.uk/gwas/">EBI GWAS catalog </a>are also included in the search to better answer this question. <p> The graph has many interactive elements. For example, clicking gene names will launch a new search for sentences containing the target gene and 200 addiction-related genes. These results help to answer the question <b>"Are there genes that can link my gene of interest to addiction?" </b> + +<p>Up to 100 gene symbols can be searched at a time. Gene symbols can be separated by either a space or a semicolon. Gene alias will <i>not</i> be automatically included because the large number of false matches associated with gene synonyms retrieved from databases. </td> <td > <div class='img'><img src="/static/ratspub.png" class="img-fluid"> - </td></tr> - <tr><td colspan=2> - - Up to 100 gene symbols can be searched at a time. Gene symbols can be separated by either a space or a semicolon. Gene alias will <i>not</i> be automatically included because the large number of false matches associated with gene synonyms retrieved from databases. - </td></tr></table> + </td> + </tr> +</table> <p> - <b>Example</b>: Rgma Nrxn3; Chrna3 + <b>Example</b>: Rgma Nrxn3 Chrna3 <br> <form action="/progress"> diff --git a/topGene_symb_alias.txt b/topGene_symb_alias.txt new file mode 100644 index 0000000..bf08e3f --- /dev/null +++ b/topGene_symb_alias.txt @@ -0,0 +1,200 @@ +CNR1 CNRS1; PROTOCADHERIN ALPHA CLUSTER, COMPLEX LOCUS +OPRM1 LMOR; M-OR-1; MOP; MOR; MOR1; OPRM; OPIOID RECEPTOR MU 1 +FOS C-FOS; P55; FOS PROTO-ONCOGENE, AP-1 TRANSCRIPTION FACTOR SUBUNIT +SLC6A3 DAT; DAT1; PKDYS; PKDYS1; SOLUTE CARRIER FAMILY 6 MEMBER 3 +CRH CRF; CRH1; CORTICOTROPIN RELEASING HORMONE +BDNF ANON2; BULN2; BRAIN DERIVED NEUROTROPHIC FACTOR +DRD2 D2DR; D2R; DOPAMINE RECEPTOR D2 +POMC ACTH; OBAIRH; PROOPIOMELANOCORTIN +CREB1 CREB; CREB-1; CAMP RESPONSIVE ELEMENT BINDING PROTEIN 1 +OPRK1 K-OR-1; KOR; KOR-1; OPRK; OPIOID RECEPTOR KAPPA 1 +TNF TNF-ALPHA; TNFA; TNFSF2; TNLG1F; TUMOR NECROSIS FACTOR +MAPK1 ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; P41; P41MAPK; P42-MAPK; MITOGEN-ACTIVATED PROTEIN KINASE 1 +SLC6A4 5-HTT; 5-HTTLPR; 5HTT; OCD1; SERT; SERT1; HSERT; SOLUTE CARRIER FAMILY 6 MEMBER 4 +CNR2 CB-2; CB2; CX5; CANNABINOID RECEPTOR 2 +OXT OT-NPI; OXT-NPI; OXYTOCIN; NEUROPHYSIN I PREPROPEPTIDE +GRM5 GPRC1E; MGLUR5; PPP1R86; MGLU5; GLUTAMATE METABOTROPIC RECEPTOR 5 +NPY PYY4; NEUROPEPTIDE Y +NOS1 IHPS1; N-NOS; NC-NOS; NOS; BNOS; NNOS; NITRIC OXIDE SYNTHASE 1 +ALDH2 ALDH-E2; ALDHI; ALDM; ALDEHYDE DEHYDROGENASE 2 FAMILY MEMBER +PNOC NOP; OFQ; PPNOC; PREPRONOCICEPTIN +GRIA1 GLUH1; GLUR1; GLURA; GLUA1; HBGR1; GLUTAMATE IONOTROPIC RECEPTOR AMPA TYPE SUBUNIT 1 +CHRNA5 LNCR2; CHOLINERGIC RECEPTOR NICOTINIC ALPHA 5 SUBUNIT +GRIN2B EIEE27; GLUN2B; MRD6; NMDAR2B; NR2B; NR3; HNR3; GLUTAMATE IONOTROPIC RECEPTOR NMDA TYPE SUBUNIT 2B +IL6 BSF-2; BSF2; HGF; HSF; IFN-BETA-2; IFNB2; IL-6; INTERLEUKIN 6 +PDYN ADCA; PENKB; SCA23; PRODYNORPHIN +GRM2 GLUR2; GPRC1B; MGLUR2; MGLU2; GLUTAMATE METABOTROPIC RECEPTOR 2 +HTR1A 5-HT-1A; 5-HT1A; 5HT1A; ADRB2RL1; ADRBRL1; PFMCD; 5-HYDROXYTRYPTAMINE RECEPTOR 1A +COMT HEL-S-98N; CATECHOL-O-METHYLTRANSFERASE +CRHR1 CRF-R; CRF-R-1; CRF-R1; CRF1; CRFR-1; CRFR1; CRH-R-1; CRH-R1; CRHR; CRHR1L; CORTICOTROPIN RELEASING HORMONE RECEPTOR 1 +GGT1 CD224; D22S672; D22S732; GGT; GGT 1; GGTD; GAMMA-GLUTAMYLTRANSFERASE 1 +MAPK3 ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; P44-ERK1; P44-MAPK; MITOGEN-ACTIVATED PROTEIN KINASE 3 +CYP2A6 CPA6; CYP2A; CYP2A3; CYPIIA6; P450C2A; P450PB; CYTOCHROME P450 FAMILY 2 SUBFAMILY A MEMBER 6 +ADH1B ADH2; HEL-S-117; ALCOHOL DEHYDROGENASE 1B CLASS I , BETA POLYPEPTIDE +GRIN1 GLUN1; MRD8; NDHMSD; NDHMSR; NMD-R1; NMDA1; NMDAR1; NR1; GLUTAMATE IONOTROPIC RECEPTOR NMDA TYPE SUBUNIT 1 +DRD4 D4DR; DOPAMINE RECEPTOR D4 +NPS NEUROPEPTIDE S +HTR2A 5-HT2A; HTR2; 5-HYDROXYTRYPTAMINE RECEPTOR 2A +GAD1 CPSQ1; GAD; SCP; GLUTAMATE DECARBOXYLASE 1 +PENK PENK-A; PROENKEPHALIN +GRIA2 GLUR2; GLURB; GLUA2; GLUR-K2; HBGR2; GLUTAMATE IONOTROPIC RECEPTOR AMPA TYPE SUBUNIT 2 +TLR4 ARMD10; CD284; TLR-4; TOLL LIKE RECEPTOR 4 +MAOA BRNRS; MAO-A; MONOAMINE OXIDASE A +ARC ARG3.1; HARC; ACTIVITY REGULATED CYTOSKELETON ASSOCIATED PROTEIN +CHRNA3 LNCR2; NACHRA3; PAOD2; CHOLINERGIC RECEPTOR NICOTINIC ALPHA 3 SUBUNIT +FOSB G0S3; GOS3; GOSB; FOSB PROTO-ONCOGENE, AP-1 TRANSCRIPTION FACTOR SUBUNIT +CYP2E1 CPE1; CYP2E; P450-J; P450C2E; CYTOCHROME P450 FAMILY 2 SUBFAMILY E MEMBER 1 +TRPV1 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 1 +IFNA1 IFL; IFN; IFN-ALPHA; IFN-ALPHAD; IFNA13; IFNA@; INTERFERON ALPHA 1 +HTR2C 5-HT1C; 5-HT2C; 5-HTR2C; 5HTR2C; HTR1C; 5-HYDROXYTRYPTAMINE RECEPTOR 2C +DBH ORTHYP1; DOPAMINE BETA-HYDROXYLASE +NGF BETA-NGF; HSAN5; NGFB; NERVE GROWTH FACTOR +GABRA2 GAMMA-AMINOBUTYRIC ACID TYPE A RECEPTOR ALPHA2 SUBUNIT +NTRK2 EIEE58; GP145-TRKB; OBHD; TRKB; TRK-B; NEUROTROPHIC RECEPTOR TYROSINE KINASE 2 +SLC1A2 EAAT2; EIEE41; GLT-1; HBGT; SOLUTE CARRIER FAMILY 1 MEMBER 2 +GRIN2A EPND; FESD; GLUN2A; LKS; NMDAR2A; NR2A; GLUTAMATE IONOTROPIC RECEPTOR NMDA TYPE SUBUNIT 2A +CRP PTX1; C-REACTIVE PROTEIN +HTR1B 5-HT-1B; 5-HT-1D-BETA; 5-HT1B; 5-HT1DB; HTR1D2; HTR1DB; 5-HYDROXYTRYPTAMINE RECEPTOR 1B +ANKK1 PKK2; SGK288; ANKYRIN REPEAT AND KINASE DOMAIN CONTAINING 1 +OPRD1 DOP; DOR1; OPRD; OPIOID RECEPTOR DELTA 1 +GFAP ALXDRD; GLIAL FIBRILLARY ACIDIC PROTEIN +CHRNB4 CHOLINERGIC RECEPTOR NICOTINIC BETA 4 SUBUNIT +CALCA CALC1; CGRP; CGRP-I; CGRP1; PCT; CALCITONIN RELATED POLYPEPTIDE ALPHA +IL10 CSIF; GVHDS; IL-10; IL10A; TGIF; INTERLEUKIN 10 +JUN AP1; C-JUN; JUN PROTO-ONCOGENE, AP-1 TRANSCRIPTION FACTOR SUBUNIT +PSENEN ACNINV2; MDS033; MSTP064; PEN-2; PEN2; PRESENILIN ENHANCER, GAMMA-SECRETASE SUBUNIT +PTGS2 COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; HCOX-2; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE 2 +CYP3A4 CP33; CP34; CYP3A; CYP3A3; CYPIIIA3; CYPIIIA4; HLP; NF-25; P450C3; P450PCN1; CYTOCHROME P450 FAMILY 3 SUBFAMILY A MEMBER 4 +ADH1C ADH3; ALCOHOL DEHYDROGENASE 1C CLASS I , GAMMA POLYPEPTIDE +GDNF ATF1; ATF2; HFB1-GDNF; HSCR3; GLIAL CELL DERIVED NEUROTROPHIC FACTOR +GRM1 GPRC1A; MGLU1; MGLUR1; PPP1R85; SCA44; SCAR13; GLUTAMATE METABOTROPIC RECEPTOR 1 +DRD1 DADR; DRD1A; DOPAMINE RECEPTOR D1 +MTOR FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS; MECHANISTIC TARGET OF RAPAMYCIN KINASE +BCHE BCHED; CHE1; CHE2; BUTYRYLCHOLINESTERASE +PPARA NR1C1; PPAR; PPARALPHA; HPPAR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA +TRH PRO-TRH; THYROTROPIN RELEASING HORMONE +OPRL1 KOR-3; NOCIR; NOPR; ORL1; OPIOID RELATED NOCICEPTIN RECEPTOR 1 +IL2 IL-2; TCGF; INTERLEUKIN 2 +RTN4 NOGO; NSP; NSP-CL; NBLA00271; NBLA10545; RTN-X; RTN4-A; RTN4-B1; RTN4-B2; RTN4-C; RETICULON 4 +PPP1R1B DARPP-32; DARPP32; PROTEIN PHOSPHATASE 1 REGULATORY INHIBITOR SUBUNIT 1B +DRD3 D3DR; ETM1; FET1; DOPAMINE RECEPTOR D3 +CYP2B6 CPB6; CYP2B; CYP2B7; CYP2B7P; CYPIIB6; EFVM; IIB1; CYTOCHROME P450 FAMILY 2 SUBFAMILY B MEMBER 6 +ABCB1 ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1; ATP BINDING CASSETTE SUBFAMILY B MEMBER 1 +MGLL HU-K5; HUK5; MAGL; MGL; MONOGLYCERIDE LIPASE +CCL2 GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF; C-C MOTIF CHEMOKINE LIGAND 2 +NOS2 HEP-NOS; INOS; NOS2A; NITRIC OXIDE SYNTHASE 2 +EGFR ERBB; ERBB1; HER1; NISBD2; PIG61; MENA; EPIDERMAL GROWTH FACTOR RECEPTOR +HOMER1 HOMER; HOMER1A; HOMER1B; HOMER1C; SYN47; VES-1; HOMER SCAFFOLD PROTEIN 1 +BCL2 BCL-2; PPP1R50; BCL2 APOPTOSIS REGULATOR +PLAT T-PA; TPA; PLASMINOGEN ACTIVATOR, TISSUE TYPE +IL1B IL-1; IL1-BETA; IL1F2; INTERLEUKIN 1 BETA +HCRTR1 OX1R; HYPOCRETIN RECEPTOR 1 +CDK5 LIS7; PSSALRE; CYCLIN DEPENDENT KINASE 5 +ADA2 ADGF; CECR1; IDGFL; PAN; SNEDS; VAIHS; ADENOSINE DEAMINASE 2 +CHAT CHOACTASE; CMS1A; CMS1A2; CMS6; CHOLINE O-ACETYLTRANSFERASE +MAP2K7 JNKK2; MAPKK7; MEK; MEK 7; MKK7; PRKMK7; SAPKK-4; SAPKK4; MITOGEN-ACTIVATED PROTEIN KINASE KINASE 7 +IL4 BCGF-1; BCGF1; BSF-1; BSF1; IL-4; INTERLEUKIN 4 +BAX BCL2L4; BCL2 ASSOCIATED X, APOPTOSIS REGULATOR +SLC18A2 PKDYS2; SVAT; SVMT; VAT2; VMAT2; SOLUTE CARRIER FAMILY 18 MEMBER A2 +MAPK8 JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1C; MITOGEN-ACTIVATED PROTEIN KINASE 8 +ADORA2A A2AR; ADORA2; RDC8; ADENOSINE A2A RECEPTOR +PIK3CD APDS; IMD14; P110DELTA; PI3K; P110D; PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA +CHRNA4 BFNC; EBN1; NACHRA4; NACRA4; CHOLINERGIC RECEPTOR NICOTINIC ALPHA 4 SUBUNIT +SRC SRC1; THC6; C-SRC; P60-SRC; SRC PROTO-ONCOGENE, NON-RECEPTOR TYROSINE KINASE +NPFF FMRFAL; NEUROPEPTIDE FF-AMIDE PEPTIDE PRECURSOR +HOMER2 ACPD; DFNA68; HOMER-2; VESL-2; HOMER SCAFFOLD PROTEIN 2 +EGR1 AT225; G0S30; KROX-24; NGFI-A; TIS8; ZIF-268; ZNF225; EARLY GROWTH RESPONSE 1 +ACHE ACEE; ARACHE; N-ACHE; ACETYLCHOLINESTERASE CARTWRIGHT BLOOD GROUP +NKS1 'EC-1; NATURAL KILLER CELL SUSCEPTIBILITY 1 +GNRH1 GNRH; LHRH; LNRH; GONADOTROPIN RELEASING HORMONE 1 +EGF HOMG4; EPIDERMAL GROWTH FACTOR +CRHR2 CRF-RB; CRF2; CRFR2; HM-CRF; CORTICOTROPIN RELEASING HORMONE RECEPTOR 2 +TAAR1 TAR1; TRAR1; TRACE AMINE ASSOCIATED RECEPTOR 1 +ADA ADENOSINE DEAMINASE +MECP2 AUTSX3; MRX16; MRX79; MRXS13; MRXSL; PPMX; METHYL-CPG BINDING PROTEIN 2 +APOE APO-E; APOE4; LDLCQ5; APOLIPOPROTEIN E +NFKB1 CVID12; EBP-1; KBF1; NF-KB1; NF-KAPPA-B1; NF-KAPPAB; NFKB-P105; NFKB-P50; NFKAPPAB; NUCLEAR FACTOR KAPPA B SUBUNIT 1 +TPH2 ADHD7; NTPH; TRYPTOPHAN HYDROXYLASE 2 +PRKAB1 AMPK; HAMPKB; PROTEIN KINASE AMP-ACTIVATED NON-CATALYTIC SUBUNIT BETA 1 +PRKAA2 AMPK; AMPK2; AMPKA2; PRKAA; PROTEIN KINASE AMP-ACTIVATED CATALYTIC SUBUNIT ALPHA 2 +PRKAA1 AMPK; AMPKA1; PROTEIN KINASE AMP-ACTIVATED CATALYTIC SUBUNIT ALPHA 1 +MMP9 CLG4B; GELB; MANDP2; MMP-9; MATRIX METALLOPEPTIDASE 9 +ADH7 ADH4; ALCOHOL DEHYDROGENASE 7 CLASS IV , MU OR SIGMA POLYPEPTIDE +MPO MYELOPEROXIDASE +VEGFA MVCD1; VEGF; VASCULAR ENDOTHELIAL GROWTH FACTOR A +HCRT NRCLP1; PPOX; HYPOCRETIN NEUROPEPTIDE PRECURSOR +CYP1A1 AHRR; CP11; CYP1; CYPIA1; P1-450; P450-C; P450DX; CYTOCHROME P450 FAMILY 1 SUBFAMILY A MEMBER 1 +CHRNB3 CHOLINERGIC RECEPTOR NICOTINIC BETA 3 SUBUNIT +CHRNB2 EFNL3; NACHRB2; CHOLINERGIC RECEPTOR NICOTINIC BETA 2 SUBUNIT +VIP PHM27; VASOACTIVE INTESTINAL PEPTIDE +TACR1 NK1R; NKIR; TAC1R; TACHYKININ RECEPTOR 1 +RGS9 PERRS; RGS9L; REGULATOR OF G PROTEIN SIGNALING 9 +NR4A2 HZF-3; NURR1; RNR1; TINUR; NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 2 +HCRTR2 OX2R; HYPOCRETIN RECEPTOR 2 +GRM3 GLUR3; GPRC1C; MGLUR3; MGLU3; GLUTAMATE METABOTROPIC RECEPTOR 3 +CYP1A2 CP12; CYPIA2; P3-450; P450 PA ; CYTOCHROME P450 FAMILY 1 SUBFAMILY A MEMBER 2 +AP5B1 AP-5; PP1030; ADAPTOR RELATED PROTEIN COMPLEX 5 SUBUNIT BETA 1 +PRKCG PKC-GAMMA; PKCC; PKCG; PKCI 3 ; PKCGAMMA; SCA14; PROTEIN KINASE C GAMMA +SIRT1 SIR2; SIR2L1; SIR2ALPHA; SIRTUIN 1 +RGS4 RGP4; SCZD9; REGULATOR OF G PROTEIN SIGNALING 4 +PTH PTH1; PARATHYROID HORMONE +PER2 FASPS; FASPS1; PERIOD CIRCADIAN REGULATOR 2 +FGF2 BFGF; FGF-2; FGFB; HBGF-2; FIBROBLAST GROWTH FACTOR 2 +ADH1A ADH1; ALCOHOL DEHYDROGENASE 1A CLASS I , ALPHA POLYPEPTIDE +GRM7 GLUR7; GPRC1G; MGLU7; MGLUR7; PPP1R87; GLUTAMATE METABOTROPIC RECEPTOR 7 +ADH4 ADH-2; HEL-S-4; ALCOHOL DEHYDROGENASE 4 CLASS II , PI POLYPEPTIDE +NOS3 ECNOS; ENOS; NITRIC OXIDE SYNTHASE 3 +ITGAM CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6; INTEGRIN SUBUNIT ALPHA M +GSTM1 GST1; GSTM1-1; GSTM1A-1A; GSTM1B-1B; GTH4; GTM1; GLUTATHIONE S-TRANSFERASE MU 1 +GPR55 LPIR1; G PROTEIN-COUPLED RECEPTOR 55 +CYP2C19 CPCJ; CYP2C; CYPIIC17; CYPIIC19; P450C2C; P450IIC19; CYTOCHROME P450 FAMILY 2 SUBFAMILY C MEMBER 19 +CCKBR 'xxCCK-B; CCK2R; GASR; CHOLECYSTOKININ B RECEPTOR +TANK I-TRAF; ITRAF; TRAF2; TRAF FAMILY MEMBER ASSOCIATED NFKB ACTIVATOR +NCAM1 CD56; MSK39; NCAM; NEURAL CELL ADHESION MOLECULE 1 +KCNJ6 BIR1; GIRK-2; GIRK2; KATP-2; KATP2; KCNJ7; KIR3.2; KPLBS; HIGIRK2; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY J MEMBER 6 +HMGB1 HMG-1; HMG1; HMG3; SBP-1; HIGH MOBILITY GROUP BOX 1 +HDAC2 KDAC2; RPD3; YAF1; HISTONE DEACETYLASE 2 +CHRM2 CHOLINERGIC RECEPTOR MUSCARINIC 2 +CCL5 D17S136E; RANTES; SCYA5; SIS-DELTA; SISD; TCP228; EOCP; C-C MOTIF CHEMOKINE LIGAND 5 +ADCYAP1 PACAP; ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE 1 +SULT2A1 DHEA-ST; DHEAS; ST2A1; ST2A3; HSTA; SULFOTRANSFERASE FAMILY 2A MEMBER 1 +PER1 RIGUI; HPER; PERIOD CIRCADIAN REGULATOR 1 +MMP2 CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1; MATRIX METALLOPEPTIDASE 2 +ARRB2 ARB2; ARR2; BARR2; ARRESTIN BETA 2 +AGRP AGRT; ASIP2; AGOUTI RELATED NEUROPEPTIDE +SOD2 IPO-B; IPOB; MNSOD; MVCD6; MN-SOD; SUPEROXIDE DISMUTASE 2 +MBP MYELIN BASIC PROTEIN +GAD2 GAD65; GLUTAMATE DECARBOXYLASE 2 +EIF4EBP1 4E-BP1; 4EBP1; BP-1; PHAS-I; EUKARYOTIC TRANSLATION INITIATION FACTOR 4E BINDING PROTEIN 1 +CREM CREM-2; ICER; HCREM-2; CAMP RESPONSIVE ELEMENT MODULATOR +CHRNA6 CHNRA6; CHOLINERGIC RECEPTOR NICOTINIC ALPHA 6 SUBUNIT +ALK CD246; NBLST3; ALK RECEPTOR TYROSINE KINASE +UGT2B7 UDPGT 2B7; UDPGT 2B9; UDPGT2B7; UDPGTH2; UDPGTH-2; UGT2B9; UDP GLUCURONOSYLTRANSFERASE FAMILY 2 MEMBER B7 +UGT1A4 GNT1; HUG-BR2; UDPGT; UDPGT 1-4; UGT-1A; UGT-1D; UGT1; UGT1-01; UGT1-04; UGT1.1; UGT1.4; UGT1A; UGT1A1; UGT1A4S; UGT1D; HUG-BR1; UDP GLUCURONOSYLTRANSFERASE FAMILY 1 MEMBER A4 +SLC1A3 EAAT1; GLAST; GLAST1; SOLUTE CARRIER FAMILY 1 MEMBER 3 +SHBG TEBG; SEX HORMONE BINDING GLOBULIN +PARP1 ADPRT; ADPRT 1; ADPRT1; ARTD1; PARP; PARP-1; PPOL; PADPRT-1; POLY ADP-RIBOSE POLYMERASE 1 +NLRP3 AGTAVPRL; C1ORF7; CIAS1; CLR1.1; DFNA34; FCAS; FCAS1; KEFH; NALP3; PYPAF1; NLR FAMILY PYRIN DOMAIN CONTAINING 3 +NFE2L2 HEBP1; IMDDHH; NRF2; NUCLEAR FACTOR, ERYTHROID 2 LIKE 2 +IL1RN DIRA; ICIL-1RA; IL-1RN; IL-1RA; IL-1RA3; IL1F3; IL1RA; IRAP; MVCD4; INTERLEUKIN 1 RECEPTOR ANTAGONIST +GABPA E4TF1-60; E4TF1A; NFT2; NRF2; NRF2A; RCH04A07; GA BINDING PROTEIN TRANSCRIPTION FACTOR SUBUNIT ALPHA +FKBP5 AIG6; FKBP51; FKBP54; PPIASE; PTG-10; FKBP PROLYL ISOMERASE 5 +ALDH1A1 ALDC; ALDH-E1; ALDH1; ALDH11; HEL-9; HEL-S-53E; HEL12; PUMB1; RALDH1; ALDEHYDE DEHYDROGENASE 1 FAMILY MEMBER A1 +UGT1A6 GNT1; HLUGP; HLUGP1; UDPGT; UDPGT 1-6; UGT-1A; UGT-1C; UGT-1E; UGT1; UGT1-01; UGT1-03; UGT1-05; UGT1.1; UGT1.3; UGT1.5; UGT1A; UGT1A1; UGT1A3; UGT1A5; UGT1A6S; UGT1C; UGT1E; UGT1F; HUG-BR1; UDP GLUCURONOSYLTRANSFERASE FAMILY 1 MEMBER A6 +SIGMAR1 ALS16; DSMA2; OPRS1; SIG-1R; SR-BP; SR-BP1; SRBP; HSIGMAR1; SIGMA1R; SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1 +RAC1 MIG5; MRD48; RAC-1; TC-25; P21-RAC1; RAC FAMILY SMALL GTPASE 1 +P4HTM EGLN4; HIFPH4; P4H-TM; 'PH-4; PHD4; PROLYL 4-HYDROXYLASE, TRANSMEMBRANE +KRAS C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; K-RAS; KI-RAS; KRAS1; KRAS2; RALD; RASK2; C-KI-RAS2; KRAS PROTO-ONCOGENE, GTPASE +IL18 IGIF; IL-18; IL-1G; IL1F4; INTERLEUKIN 18 +HTR3A 5-HT-3; 5-HT3A; 5-HT3R; 5HT3R; HTR3; 5-HYDROXYTRYPTAMINE RECEPTOR 3A +HSPA4 APG-2; HEL-S-5A; HS24/P52; HSPH2; HSP70; HSP70RY; HEAT SHOCK PROTEIN FAMILY A HSP70 MEMBER 4 +FYN P59-FYN; FYN PROTO-ONCOGENE, SRC FAMILY TYROSINE KINASE +COL11A2 DFNA13; DFNB53; FBCG2; HKE5; OSMEDA; OSMEDB; PARP; STL3; COLLAGEN TYPE XI ALPHA 2 CHAIN +UGT1A7 GNT1; UDPGT; UDPGT 1-7; UGT-1A; UGT-1G; UGT1; UGT1-01; UGT1-07; UGT1.1; UGT1.7; UGT1A; UGT1A1; UGT1G; HUG-BR1; UDP GLUCURONOSYLTRANSFERASE FAMILY 1 MEMBER A7 +TRPA1 ANKTM1; FEPS; FEPS1; TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY A MEMBER 1 +STAT3 ADMIO; ADMIO1; APRF; HIES; SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3 +PRKCA AAG6; PKC-ALPHA; PKCA; PKCI+/-; PKCALPHA; PRKACA; PROTEIN KINASE C ALPHA +MTHFR METHYLENETETRAHYDROFOLATE REDUCTASE +GRK2 ADRBK1; BARK1; BETA-ARK1; G PROTEIN-COUPLED RECEPTOR KINASE 2 +DNMT1 ADCADN; CXXC9; DNMT; HSN1E; MCMT; M.HSAI; DNA METHYLTRANSFERASE 1 +UGT1A8 GNT1; UDPGT; UDPGT 1-8; UGT-1A; UGT-1H; UGT1; UGT1-01; UGT1-08; UGT1.1; UGT1.8; UGT1A; UGT1A1; UGT1A8S; UGT1H; HUG-BR1; UDP GLUCURONOSYLTRANSFERASE FAMILY 1 MEMBER A8 |
