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-rw-r--r--gn/packages/bioinformatics.scm60
1 files changed, 60 insertions, 0 deletions
diff --git a/gn/packages/bioinformatics.scm b/gn/packages/bioinformatics.scm
index 4c2f8cf..67b2270 100644
--- a/gn/packages/bioinformatics.scm
+++ b/gn/packages/bioinformatics.scm
@@ -3138,3 +3138,63 @@ from a VCF. In particular, pixy facilitates the use of VCFs containing
invariant (monomorphic) sites, which are essential for the correct computation
of π and dxy in the face of missing data (i.e. always).")
(license license:expat)))
+
+(define-public wfa2-lib
+ (let ((commit "af6be887614e8bb4e2b6e8c4e500705a978bd513") ; 14 April 2022
+ (revision "1"))
+ (package
+ (name "wfa2-lib")
+ (version (git-version "2.1" revision commit)) ; As seen in ./VERSION
+ (source (origin
+ (method git-fetch)
+ (uri (git-reference
+ (url "https://github.com/smarco/WFA2-lib")
+ (commit commit)))
+ (file-name (git-file-name name version))
+ (sha256
+ (base32 "09gsmks4dzmfscklb60m6gcsvsd9r6jywf10633dpcsfsdcvmzaw"))
+ (snippet
+ #~(begin
+ (use-modules ((guix build utils)))
+ (substitute* "Makefile"
+ (("^CC=") "CC:=")
+ (("^CPP=") "CPP:=")
+ (("-march=native") ""))))))
+ (build-system gnu-build-system)
+ (arguments
+ (list
+ #:tests? #f ; No tests.
+ #:parallel-build? #f ; Race condition in Makefile.
+ #:modules '((guix build gnu-build-system)
+ (guix build utils)
+ (srfi srfi-26))
+ #:make-flags
+ #~(list (string-append "CC=" #$(cc-for-target))
+ (string-append "CPP=" #$(cxx-for-target)))
+ #:phases
+ #~(modify-phases %standard-phases
+ (delete 'configure) ; No configure script.
+ ;; -flto breaks align_benchmark.
+ (replace 'build
+ (lambda* (#:key (make-flags '()) #:allow-other-keys)
+ (apply invoke "make" "all" make-flags)))
+ (replace 'install
+ (lambda _
+ (for-each
+ (cut install-file <> (string-append #$output "/bin"))
+ (find-files "bin"))
+ (for-each
+ (cut install-file <> (string-append #$output "/lib"))
+ (find-files "lib")))))))
+ (home-page "https://github.com/smarco/WFA2-lib")
+ (synopsis "Wavefront alignment algorithm library")
+ (description "The @acronym{wavefront alignment, WFA} algorithm is an exact
+gap-affine algorithm that takes advantage of homologous regions between the
+sequences to accelerate the alignment process. Unlike to traditional dynamic
+programming algorithms that run in quadratic time, the WFA runs in time
+@code{O(ns+s^2)}, proportional to the sequence length @code{n} and the alignment
+score @code{s}, using @code{O(s^2)} memory. Moreover, the WFA algorithm
+exhibits simple computational patterns that the modern compilers can
+automatically vectorize for different architectures without adapting the code.")
+ (properties '((tunable? . #t)))
+ (license license:expat))))