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authorjgart2021-11-24 00:39:40 -0500
committerjgart2021-11-24 00:39:40 -0500
commit1259ed80a7f60a9f7ba82f3751990ac24a8e9436 (patch)
tree8f235d104edf59e78d74b5e4f997a4dc57c4c013 /topics/quality-control/qc-checks.gmi
parentf46ed96a01617514547da4636b6121fadc5f2326 (diff)
downloadgn-gemtext-1259ed80a7f60a9f7ba82f3751990ac24a8e9436.tar.gz
Add citation for Shapiro-Wilk Test
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@@ -58,3 +58,16 @@ phenotypes.
--
Rob
```
+
+```
+QTL analysis was performed in F2 mice using the R package R/qtl
+(RRID:SCR_009085) as previously described.11,29,42 Quality checking
+of genotypes and QTL analysis were performed in R (https://www.r-
+project.org/) using R/bestNormalize (https://github.com/petersonR/
+bestNormalize) and R/qtl.42 Phenotypes were assessed for normality
+using the Shapiro–Wilk Test. Because some of the data residuals devi-
+ated significantly from normality, we used the orderNorm function to
+perform Ordered Quantile normalization43 on all phenotypes. QTL
+--
+A quantitative trait variant in Gabra2 underlies increased methamphetamine stimulant sensitivity
+```