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authorRob Williams2022-04-18 13:41:15 -0500
committerGitHub2022-04-18 13:41:15 -0500
commite07e5e26a55e613c444d0c9b3fb2cea21011b194 (patch)
treede8fe5143afd67b09b40767f8fadeb2d1fb70014 /issues
parent058f21ffeea4009cb6224f0c3f2ef6d7e10524a9 (diff)
downloadgn-gemtext-e07e5e26a55e613c444d0c9b3fb2cea21011b194.tar.gz
Create Effect size for GEMMA is a MUST
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+To: @Zach, @Pjotr
+From: robwwilliams
+Regarding: Getting a readout of effect size and polarity of effect from GEMMA
+Request Type: New feature for GEMMA, User requires these data
+
+Main Message: Let's Just Do It. Can be done as a kludge. Just plot the beta of the regression equation of the SNP status (ususally two or three states codes as 0, 1, 2 or -1,0, +1) against the phenotype.
+The slope is roughly the effect size. This is good enough for most users. The only got-you is slight inflation of due to kinship structure and the Beavis effect when the sample size is low.
+QUESTION—can I upload an image from Amelie Baud's talk on effect size?