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authorArun Isaac2022-04-19 22:08:35 +0530
committerArun Isaac2022-04-19 22:08:35 +0530
commitad2bb5b65f2e3c5679b5d17de3f9b4050577f996 (patch)
tree4b26c34ed13dffc36a946fbac0483c7edeafbf78 /issues/effect-size-for-gemma-is-a-must.gmi
parente07e5e26a55e613c444d0c9b3fb2cea21011b194 (diff)
downloadgn-gemtext-ad2bb5b65f2e3c5679b5d17de3f9b4050577f996.tar.gz
Add gmi extension to gemma effect size issue. Add title.
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+# Effect size for GEMMA is a MUST
+
+To: @Zach, @Pjotr
+From: robwwilliams
+Regarding: Getting a readout of effect size and polarity of effect from GEMMA
+Request Type: New feature for GEMMA, User requires these data
+
+Main Message: Let's Just Do It. Can be done as a kludge. Just plot the beta of the regression equation of the SNP status (ususally two or three states codes as 0, 1, 2 or -1,0, +1) against the phenotype.
+The slope is roughly the effect size. This is good enough for most users. The only got-you is slight inflation of due to kinship structure and the Beavis effect when the sample size is low.
+QUESTION—can I upload an image from Amelie Baud's talk on effect size?