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| -rw-r--r-- | api/GN3-REST-API-Implementation.md | 224 |
1 files changed, 76 insertions, 148 deletions
diff --git a/api/GN3-REST-API-Implementation.md b/api/GN3-REST-API-Implementation.md index 4f02bf0..d759e94 100644 --- a/api/GN3-REST-API-Implementation.md +++ b/api/GN3-REST-API-Implementation.md @@ -836,61 +836,62 @@ Example Result "pages": "ex:totalCount", "pubmed": "dct:references", "rdfs": "http://www.w3.org/2000/01/rdf-schema#", + "species": "ex:species", "type": "@type", "xsd": "http://www.w3.org/2001/XMLSchema#" }, "currentPage": 0, "entries": [ { + "author": "Robert Williams", "category": "Genetic variation and alleles", - "comment": "Individual probe analysis:probably true cisQTL", - "created": "2007-10-05T09:09:52", - "ex:species": "Mouse (Mus musculus, mm10)", - "pubmed": "" + "comment": "cis eQTL in BXD brain RNA-seq data with LRS of 33 and high D allele. No obvious trans target transcripts.", + "created": "2012-11-10T07:30:09", + "pubmed": "", + "species": "Mouse (Mus musculus, mm10)" }, { - "category": "Expression patterns: mature cells, tissues; Gene structure and organization; Genetic variation and alleles", - "comment": "cis QTL present in hippocampus LXS, ILM2970706 distal 3' UTR, 121.4 LRS, ISS increases the trait;", - "created": "2007-05-10T05:52:22", - "ex:species": "Mouse (Mus musculus, mm10)", - "pubmed": "" + "category": "Genetic variation and alleles", + "comment": "Individual probe analysis:probably true cisQTL", + "created": "2007-10-05T09:09:52", + "pubmed": "", + "species": "Mouse (Mus musculus, mm10)" }, { "category": "", "comment": "hippocampal CA1-3 expression signature", "created": "2005-12-16T15:23:23", - "ex:species": "Mouse (Mus musculus, mm10)", - "pubmed": "http://rdf.ncbi.nlm.nih.gov/pubmed/15084669" + "pubmed": "http://rdf.ncbi.nlm.nih.gov/pubmed/15084669", + "species": "Mouse (Mus musculus, mm10)" }, { "category": "Probes and probe sets; Transcriptional and translation control", "comment": "Validated strong cis-QTL in CNS using allele-specific expression ASE SNaPshot assay Daniel Ciobanu and al., 2007. Possible 3' UTR variants.", "created": "2007-05-08T09:46:07", - "ex:species": "Mouse (Mus musculus, mm10)", - "pubmed": "" + "pubmed": "", + "species": "Mouse (Mus musculus, mm10)" }, { - "author": "Robert Williams", - "category": "Genetic variation and alleles", - "comment": "cis eQTL in BXD brain RNA-seq data with LRS of 33 and high D allele. No obvious trans target transcripts.", - "created": "2012-11-10T07:30:09", - "ex:species": "Mouse (Mus musculus, mm10)", - "pubmed": "" + "category": "Expression patterns: mature cells, tissues; Gene structure and organization; Genetic variation and alleles", + "comment": "cis QTL present in hippocampus LXS, ILM2970706 distal 3' UTR, 121.4 LRS, ISS increases the trait;", + "created": "2007-05-10T05:52:22", + "pubmed": "", + "species": "Mouse (Mus musculus, mm10)" }, { "category": "Health and disease associations", "comment": "Merck, Rosetta, Schadt, Lusis target gene associated with obesity, diabetes and atherosclerosis.", "created": "2008-05-13T08:48:50", - "ex:species": "Mouse (Mus musculus, mm10)", - "pubmed": "" + "pubmed": "", + "species": "Mouse (Mus musculus, mm10)" }, { "author": "Robert Williams", "category": "", "comment": "Of interest to Lu Lu and colleagues 2015 due to modulation of expression of this gene in hippocampus following stress or ethanol BXD Illumina Hippocampus data sets.", "created": "2015-05-26T11:37:57", - "ex:species": "Mouse (Mus musculus, mm10)", - "pubmed": "" + "pubmed": "", + "species": "Mouse (Mus musculus, mm10)" } ], "id": "http://genenetwork.org/id/symbolLpl", @@ -899,13 +900,13 @@ Example Result } ``` -## GET /genewiki/ncbi/:symol +## GET /genewiki/ncbi/:symbol Get genewiki entries from NCBI about a given symbol *Parameters:* page(default=0), per-page(default=10) ``` -curl "localhost:8080/api/metadata/genewikis/ncbi/Lpl" +curl "localhost:8080/api/metadata/genewikis/ncbi/Lpl?per-page=3" ``` Example Result @@ -913,134 +914,61 @@ Example Result ``` { "@context": { - "author": "dct:creator", - "category": "gnt:belongsToCategory", - "comment": "rdfs:comment", + "author": "dct:creator", + "category": "gnt:belongsToCategory", + "comment": "rdfs:comment", "created": { - "@id": "dct:created", + "@id": "dct:created", "@type": "xsd:datetime" - }, - "currentPage": "ex:currentPage", - "data": "@graph", - "dct": "http://purl.org/dc/terms/", - "entries": "ex:entries", - "ex": "http://example.org/stuff/1.0/", - "gnc": "http://genenetwork.org/category/", - "gnt": "http://genenetwork.org/term/", - "id": "@id", - "pages": "ex:totalCount", - "pubmed": "dct:references", - "rdfs": "http://www.w3.org/2000/01/rdf-schema#", - "type": "@type", + }, + "currentPage": "ex:currentPage", + "data": "@graph", + "dct": "http://purl.org/dc/terms/", + "entries": "ex:entries", + "ex": "http://example.org/stuff/1.0/", + "geneId": "gnt:hasGeneId", + "gnc": "http://genenetwork.org/category/", + "gnt": "http://genenetwork.org/term/", + "id": "@id", + "pages": "ex:totalCount", + "pubmed": "dct:references", + "rdfs": "http://www.w3.org/2000/01/rdf-schema#", + "species": "ex:species", + "type": "@type", "xsd": "http://www.w3.org/2001/XMLSchema#" - }, - "data": [ + }, + "currentPage": 0, + "entries": [ { - "currentPage": 0, - "entries": [ - { - "comment": "Results support the use of LPL and ADAM29 gene expression associated to IGHV mutational status for predicting the clinical outcome of patients treated by oral fludarabine + cyclophosphamide and could be considered for treatment strategies.", - "created": "2010-01-20T18:00:00", - "ex:species": "Human (Homo sapiens, hg19)", - "gnt:hasGeneId": { - "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=4023" - }, - "pubmed": "" - }, - { - "comment": "Observational study of gene-disease association and pharmacogenomic / toxicogenomic. HuGE Navigator", - "created": "2009-02-11T15:30:00", - "ex:species": "Human (Homo sapiens, hg19)", - "gnt:hasGeneId": { - "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=4023" - }, - "pubmed": "" - }, - { - "comment": "analysis of human placental lipoprotein lipase gestational and hormonal regulation", - "created": "2010-01-20T18:00:00", - "ex:species": "Human (Homo sapiens, hg19)", - "gnt:hasGeneId": { - "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=4023" - }, - "pubmed": "" - }, - { - "comment": "LPL 44X alleles were associated with moderately increased LDL peak particle size.", - "created": "2010-01-20T18:00:00", - "ex:species": "Human (Homo sapiens, hg19)", - "gnt:hasGeneId": { - "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=4023" - }, - "pubmed": "" - }, - { - "comment": "LPL gene variant is involved in carotid atherosclerotic lesions.", - "created": "2010-01-20T18:00:00", - "ex:species": "Human (Homo sapiens, hg19)", - "gnt:hasGeneId": { - "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=4023" - }, - "pubmed": "" - }, - { - "comment": "Metformin may increase LPL production, thereby increasing low density lipoprotein particle size which may be independent of the hypoglycemic effect of metforminin type 2 diabetes.", - "created": "2010-01-20T18:00:00", - "ex:species": "Human (Homo sapiens, hg19)", - "gnt:hasGeneId": { - "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=4023" - }, - "pubmed": "" - }, - { - "comment": "LPL may represent a link between low adiponectin levels and dyslipidemia in both nondiabetic individuals and patients with type 2 diabetes.", - "created": "2010-01-20T18:00:00", - "ex:species": "Human (Homo sapiens, hg19)", - "gnt:hasGeneId": { - "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=4023" - }, - "pubmed": "" - }, - { - "comment": "The PvuII polymorphism cannot be used as independent genetic risk factor for coronary artery disease in patients of Saudi Arabic descent.", - "created": "2010-01-20T18:00:00", - "ex:species": "Human (Homo sapiens, hg19)", - "gnt:hasGeneId": { - "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=4023" - }, - "pubmed": "" - } - ], - "id": "http://genenetwork.org/id/symbolLPL", - "pages": 48, - "type": "gnc:GNWikiEntry" - }, + "comment": "LPL gene variant is involved in carotid atherosclerotic lesions.", + "created": "2010-01-20T18:00:00", + "geneId": { + "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=4023" + }, + "pubmed": "", + "species": "Human (Homo sapiens, hg19)" + }, { - "currentPage": 0, - "entries": [ - { - "comment": "LPL activity can be inhibited by endogenous apoC-I in apoE-knockout mice.", - "created": "2010-01-20T18:00:00", - "ex:species": "Mouse (Mus musculus, mm10)", - "gnt:hasGeneId": { - "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=16956" - }, - "pubmed": "" - }, - { - "comment": "STZ-induced diabetes causes a decrease in LPL activity in the sciatic nerve that is reversible with insulin treatment", - "created": "2010-01-20T18:00:00", - "ex:species": "Rat (Rattus norvegicus, rn7.2)", - "gnt:hasGeneId": { - "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=24539" - }, - "pubmed": "" - } - ], - "id": "http://genenetwork.org/id/symbolLpl", - "pages": 48, - "type": "gnc:GNWikiEntry" + "comment": "LPL 44X alleles were associated with moderately increased LDL peak particle size.", + "created": "2010-01-20T18:00:00", + "geneId": { + "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=4023" + }, + "pubmed": "", + "species": "Human (Homo sapiens, hg19)" + }, + { + "comment": "Observational study of gene-disease association and pharmacogenomic / toxicogenomic. HuGE Navigator", + "created": "2009-02-11T15:30:00", + "geneId": { + "id": "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=4023" + }, + "pubmed": "", + "species": "Human (Homo sapiens, hg19)" } - ] + ], + "id": "http://genenetwork.org/id/symbolLPL", + "pages": 158, + "type": "gnc:GNWikiEntry" } ``` |