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| author | Lisso_ | 2026-03-02 12:10:56 +0300 |
|---|---|---|
| committer | GitHub | 2026-03-02 12:10:56 +0300 |
| commit | 6ffe30c093b794851db096c7ea70cc7291bc6f9a (patch) | |
| tree | b8c86b6ff708232477abdac1689efab8f45fbe2b /tasks | |
| parent | 0f1a319d4ec5191fc0f66d6f2ccbe12d6f1137f5 (diff) | |
| download | gn-ai-6ffe30c093b794851db096c7ea70cc7291bc6f9a.tar.gz | |
Update Felix' tasks
* Adding a new file on progress in gn learning team * Update progress-hurdles-lessons-learned-journey.gmi My first commit to the file * Update progress-hurdles-lessons-learned-journey.gmi * A new issue on updating strain names to the GN database * updated an issue on uploading genetype names * Update hurdles_updating_names_to_GN.gmi * added my name, fixed the typo, and updated the keyword value * new updates on my learning journey * Create Case_Attributes_GN2 * Update felixl.gmi * Update felixl.gmi * updated work progress * solving bugs * Updated my tasks checklist tracker * Update quote to 'To New Beginnings'
Diffstat (limited to 'tasks')
| -rw-r--r-- | tasks/felixl.gmi | 125 |
1 files changed, 72 insertions, 53 deletions
diff --git a/tasks/felixl.gmi b/tasks/felixl.gmi index e482de8c..f943c019 100644 --- a/tasks/felixl.gmi +++ b/tasks/felixl.gmi @@ -22,28 +22,27 @@ * - [ ] list of relevant papers with one-liners - the WHY => https://pmc.ncbi.nlm.nih.gov/articles/PMC3294237/ * [+] Analyse and discuss BXD case attributes with Rob --- both group level and dataset level -* [ ] Sane representation of case attributes in RDF with @bonfacem +* [+] Sane representation of case attributes in RDF with @bonfacem * [X] Present C.elegans protocol and example mappings with GEMMA/Rqtl -* [ ] Uploader - setting up code with @fredm +* [X] Uploader - setting up code with @fredm * - [ ] Concrete improvement to work on * - [X] run small database mysql locally * - [X] aider with Sonnet + code fixes * - [ ] document - add to code base - merge with Fred's tree - share changes with Pjotr & team -* [ ] Sort @alexm application with Pwani = this week +* [X] Sort @alexm application with Pwani = this week ### This week (07-04-2025 onwards) * GN2 tasks - * [x] Progress on Kilifish - - meet with Dennis (send him an email with all the queries needed) - [-] - progress to format and upload data to gn2 (to be ready by latest Friday!) - * [x] Make a milestone with genotype smoothing +* [x] Progress on Kilifish +* [X] - meet with Dennis (send him an email with all the queries needed) +* [-] - progress to format and upload data to gn2 (to be ready by latest Friday!) +* [x] Make a milestone with genotype smoothing * PhD tasks - * [ ] Complete and share concept note and timeline to supervisors, have a meeting for progress - * [ ] Make a milestone on chapter one manuscript (deep dive into the selected papers){THE BIG PICTURE; a complete draft by early May} - * [ X ] Complete and share concept note and timeline to supervisors, have a meeting for progress - * [+] Make a milestone on chapter one manuscript (deep dive into the selected papers){THE BIG PICTURE; a complete draft by early May} + * [X] Complete and share concept note and timeline to supervisors, have a meeting for progress + * [X] Make a milestone on chapter one manuscript (deep dive into the selected papers){THE BIG PICTURE; a complete draft by early May} + * [X] Complete and share concept note and timeline to supervisors, have a meeting for progress * Programming * [x] Make a milestone with the uploader (really push and learn!) @@ -51,62 +50,62 @@ - utilise the hurdles to learn programming priniciples in action * AOBs - * [ ] Weekly meetings - * [ ] follow up with Paul on his progress - * [ ] follow up on the MSc bioinformatics project - * [ ] follow up on Alex's application with Pwani +* [X] Weekly meetings +* [X] follow up with Paul on his progress +* [X] follow up on the MSc bioinformatics project +* [X] follow up on Alex's application with Pwani ### This week (14-04-2025 onwards) * gn-uploader programming - * [X] - Resolve the config file issue with your local uploader - * [ ] - Run the uploader locally, then break the system, see how components connect to each other - * [ ] - document your findings +* [X] - Resolve the config file issue with your local uploader +* [X] - Run the uploader locally, then break the system, see how components connect to each other +* [X] - document your findings * genotype smoothing - * [ ] - resolve errors with plotting, document your findings +* [X] - resolve errors with plotting, document your findings ### This week (21-04-Onwards) * genotype smoothing - * [X] - haplotyping tools for smoothing (plink,., etc) :IN PROGRESS: - - see what it can offer with smoothing. See what others say about this. - - [X] check the original genotypes and compare with the ones in gn2 {done} - - [x] inspect the Xsome column order in comparison with the snp positioning {done} - - [x] adapt the plink algorithm to fit your dataset format {done} - - consider inspeting the phenotype file too. {in progress} +* [X] - haplotyping tools for smoothing (plink,., etc) :IN PROGRESS: +* - see what it can offer with smoothing. See what others say about this. +* - [X] check the original genotypes and compare with the ones in gn2 {done} +* - [x] inspect the Xsome column order in comparison with the snp positioning {done} +* - [x] adapt the plink algorithm to fit your dataset format {done} +* - consider inspeting the phenotype file too. {in progress} * gn-uploader programming - * [ ] - Run the uploader locally, then break the system, see how components connect to each other (ask help from Bonz) - * [ ] - document your findings +* [X] - Run the uploader locally, then break the system, see how components connect to each other (ask help from Bonz) +* [X] - document your findings ### Previous week (28-04-Onwards) * gn-uploader programming - * [X] - Run the uploader locally, then break the system, see how components connect to each other (ask help from Bonz) - - start simple, read the script files (one at a time, take your time to understand how it flows) - - In running the uploader, consider pair programming to save time with solving issues that your teamates can solve in hours, as they take you days to solve +* [X] - Run the uploader locally, then break the system, see how components connect to each other (ask help from Bonz) + - start simple, read the script files (one at a time, take your time to understand how it flows) + - In running the uploader, consider pair programming to save time with solving issues that your teamates can solve in hours, as they take you days to solve - * [ ] - document your findings - {Get help from your teammates/AI to jump start this!, swallow your pride! :(} +* [X] - document your findings + { Get help from your teammates/AI to jump start this!, swallow your pride! :(} * genotype smoothing - * [X] Keep refining the following: - * [X] filtering power adapted from plink - - the low the r2 value, the strictier the filtering.., - * [X] the xsomes mix up in the plot (probably the phenotype data?) - - individual ids in phenotype data was not in sync with the genotype data - * [X] Update findings and push to github +* [X] Keep refining the following: +* [X] filtering power adapted from plink +* - the low the r2 value, the strictier the filtering.., +* [X] the xsomes mix up in the plot (probably the phenotype data?) +* - individual ids in phenotype data was not in sync with the genotype data +* [X] Update findings and push to github ### This week (05-05-Onwards) * programming (gn-uploader) - * [ ] - pick one file each day, review it, understand it - * [ ] - pair programming with Alex on test runs +* [X] - pick one file each day, review it, understand it +* [X] - pair programming with Alex on test runs * HS rats scripts - * [X] - prepare/refine scripts to quickly process HS rats file (in progress) - [ ] - memory hurdles, goal to simplify running script - * [X] - assist alex with hs rats cross info +* [X] - prepare/refine scripts to quickly process HS rats file (in progress) +* [X] - memory hurdles, goal to simplify running script +* [X] - assist alex with hs rats cross info ### (12-05-onwards) * [X] - HS genotypes scripting @@ -127,7 +126,7 @@ * ## this week (09-06-onwards) * [+] - identify start and end points for haplotypes in hs genotype files * - checked the rembination densities first, still need more comprehension (arrange a meeting with Rob) -* [ ] - upload the final updates to gn2, test and see the results +* [X] - upload the final updates to gn2, test and see the results * [+] - gn-uploader/uploader folder, explore * ## this week (16-06-onwards) @@ -149,9 +148,9 @@ * [+] - kilifish to gn2 via backend * ## this week (30-06-onwards) -* [ ] - mapping offsprings to founders (hs rats) -* [ ] - upload kilifish to genenetwork -* [ ] - revise celegans smoothing (genotypes) +* [X] - mapping offsprings to founders (hs rats) +* [X] - upload kilifish to genenetwork +* [X] - revise celegans smoothing (genotypes) * ## this week (07-07-onwards) * [X] - generate haplotypes for offsprings and founders combined; intepretation next.., @@ -234,16 +233,36 @@ - precompute, by Pj, check on this.., - qtl results, more suggestive than absolute.., +To New Beginnings -### Later weeks +* ## this week (02-03-onwards) + +* [] - Get the qtl2_hs_pipeline working | test runs +* [] - clear definition of the root problems to the script +* [] - test runs to get quick feedback +* [] - involve the ai-lab team for more help +* [] - Kilifish data to be ready for upload +* [] - classical phenotypes and/or expression traits +* [] - metadata +* [] - genotypes; smoothing? Kilifish Genetics? +* [] - Strain, Xref, Case attributes +* [] - local gemma testing +* [] - Final checks with @Arthur et al, proceed to upload +* [] - refine the overview manuscript +* [] - the innovatio touch to be clearly defined + + +### Later weeks (2026 plan) +* [ ] Reverse Genotyping => (ML + Pan-Genome) genotyping +* [] - a paper from this experimentation * [ ] Kilifish into GN * [ ] Review paper on genotyping -* [ ] HS Rat -* [ ] Prepare others for C.elegans -* [ ] Upload Arabidopsis dataset -* [ ] Upload Medaka dataset -* [ ] Work on improved DO and Ce genotyping +* [X] HS Rat +* [-] Prepare others for C.elegans +* [+] Upload Arabidopsis dataset +* [+] Upload Medaka dataset +* [-] Work on improved DO and Ce genotyping ### Done |
