aboutsummaryrefslogtreecommitdiff
path: root/tests/unit/test_partial_correlations.py
blob: 60e54c146d26ee1911c3a22f5647f9187e76d1fc (plain)
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
"""Module contains tests for gn3.partial_correlations"""

from unittest import TestCase
from gn3.partial_correlations import (
    fix_samples,
    control_samples,
    dictify_by_samples,
    find_identical_traits)

sampleslist = ["B6cC3-1", "BXD1", "BXD12", "BXD16", "BXD19", "BXD2"]
control_traits = (
    {
        "mysqlid": 36688172,
        "data": {
            "B6cC3-1": {
                "sample_name": "B6cC3-1", "value": 7.51879, "variance": None,
                "ndata": None},
            "BXD1": {
                "sample_name": "BXD1", "value": 7.77141, "variance": None,
                "ndata": None},
            "BXD12": {
                "sample_name": "BXD12", "value": 8.39265, "variance": None,
                "ndata": None},
            "BXD16": {
                "sample_name": "BXD16", "value": 8.17443, "variance": None,
                "ndata": None},
            "BXD19": {
                "sample_name": "BXD19", "value": 8.30401, "variance": None,
                "ndata": None},
            "BXD2": {
                "sample_name": "BXD2", "value": 7.80944, "variance": None,
                "ndata": None}}},
    {
        "mysqlid": 36688172,
        "data": {
            "B6cC3-21": {
                "sample_name": "B6cC3-1", "value": 7.51879, "variance": None,
                "ndata": None},
            "BXD21": {
                "sample_name": "BXD1", "value": 7.77141, "variance": None,
                "ndata": None},
            "BXD12": {
                "sample_name": "BXD12", "value": 8.39265, "variance": None,
                "ndata": None},
            "BXD16": {
                "sample_name": "BXD16", "value": 8.17443, "variance": None,
                "ndata": None},
            "BXD19": {
                "sample_name": "BXD19", "value": 8.30401, "variance": None,
                "ndata": None},
            "BXD2": {
                "sample_name": "BXD2", "value": 7.80944, "variance": None,
                "ndata": None}}},
    {
        "mysqlid": 36688172,
        "data": {
            "B6cC3-1": {
                "sample_name": "B6cC3-1", "value": 7.51879, "variance": None,
                "ndata": None},
            "BXD1": {
                "sample_name": "BXD1", "value": 7.77141, "variance": None,
                "ndata": None},
            "BXD12": {
                "sample_name": "BXD12", "value": None, "variance": None,
                "ndata": None},
            "BXD16": {
                "sample_name": "BXD16", "value": None, "variance": None,
                "ndata": None},
            "BXD19": {
                "sample_name": "BXD19", "value": None, "variance": None,
                "ndata": None},
            "BXD2": {
                "sample_name": "BXD2", "value": 7.80944, "variance": None,
                "ndata": None}}})

dictified_control_samples = (
    {"B6cC3-1": {"sample_name": "B6cC3-1", "value": 7.51879, "variance": None},
     "BXD1": {"sample_name": "BXD1", "value": 7.77141, "variance": None},
     "BXD12": {"sample_name": "BXD12", "value": 8.39265, "variance": None},
     "BXD16": {"sample_name": "BXD16", "value": 8.17443, "variance": None},
     "BXD19": {"sample_name": "BXD19", "value": 8.30401, "variance": None},
     "BXD2": {"sample_name": "BXD2", "value": 7.80944, "variance": None}},
    {"BXD12": {"sample_name": "BXD12", "value": 8.39265, "variance": None},
     "BXD16": {"sample_name": "BXD16", "value": 8.17443, "variance": None},
     "BXD19": {"sample_name": "BXD19", "value": 8.30401, "variance": None},
     "BXD2": {"sample_name": "BXD2", "value": 7.80944, "variance": None}},
    {"B6cC3-1": {"sample_name": "B6cC3-1", "value": 7.51879, "variance": None},
     "BXD1": {"sample_name": "BXD1", "value": 7.77141, "variance": None},
     "BXD2": {"sample_name": "BXD2", "value":  7.80944, "variance": None}})

class TestPartialCorrelations(TestCase):
    """Class for testing partial correlations computation functions"""

    def test_control_samples(self):
        """Test that the control_samples works as expected."""
        self.assertEqual(
            control_samples(control_traits, sampleslist),
            ((("B6cC3-1", "BXD1", "BXD12", "BXD16", "BXD19", "BXD2"),
              ("BXD12", "BXD16", "BXD19", "BXD2"),
              ("B6cC3-1", "BXD1", "BXD2")),
             ((7.51879, 7.77141, 8.39265, 8.17443, 8.30401, 7.80944),
              (8.39265, 8.17443, 8.30401, 7.80944),
              (7.51879, 7.77141, 7.80944)),
             ((None, None, None, None, None, None), (None, None, None, None),
              (None, None, None)),
             (6, 4, 3)))

    def test_dictify_by_samples(self):
        """
        Test that `dictify_by_samples` generates the appropriate dict

        Given:
            a sequence of sequences with sample names, values and variances, as
            in the output of `gn3.partial_correlations.control_samples` or
            the output of `gn3.db.traits.export_informative`
        When:
            the sequence is passed as an argument into the
            `gn3.partial_correlations.dictify_by_sample`
        Then:
            return a sequence of dicts with keys being the values of the sample
            names, and each of who's values being sub-dicts with the keys
            'sample_name', 'value' and 'variance' whose values correspond to the
            values passed in.
        """
        self.assertEqual(
            dictify_by_samples(
                ((("B6cC3-1", "BXD1", "BXD12", "BXD16", "BXD19", "BXD2"),
                  ("BXD12", "BXD16", "BXD19", "BXD2"),
                  ("B6cC3-1", "BXD1", "BXD2")),
                 ((7.51879, 7.77141, 8.39265, 8.17443, 8.30401, 7.80944),
                  (8.39265, 8.17443, 8.30401, 7.80944),
                  (7.51879, 7.77141, 7.80944)),
                 ((None, None, None, None, None, None), (None, None, None, None),
                  (None, None, None)),
                 (6, 4, 3))),
            dictified_control_samples)

    def test_fix_samples(self):
        """
        Test that `fix_samples` returns only the common samples

        Given:
            - A primary trait
            - A sequence of control samples
        When:
            - The two arguments are passed to `fix_samples`
        Then:
            - Only the names of the samples present in the primary trait that
              are also present in ALL the control traits are present in the
              return value
            - Only the values of the samples present in the primary trait that
              are also present in ALL the control traits are present in the
              return value
            - ALL the values for ALL the control traits are present in the
              return value
            - Only the variances of the samples present in the primary trait
              that are also present in ALL the control traits are present in the
              return value
            - ALL the variances for ALL the control traits are present in the
              return value
            - The return value is a tuple of the above items, in the following
              order:
                ((sample_names, ...), (primary_trait_values, ...),
                 (control_traits_values, ...), (primary_trait_variances, ...)
                 (control_traits_variances, ...))
        """
        self.assertEqual(
            fix_samples(
                {"B6cC3-1": {"sample_name": "B6cC3-1", "value": 7.51879,
                             "variance": None},
                 "BXD1": {"sample_name": "BXD1", "value": 7.77141,
                          "variance": None},
                 "BXD2": {"sample_name": "BXD2", "value":  7.80944,
                          "variance": None}},
                dictified_control_samples),
            (("BXD2",), (7.80944,),
             (7.51879, 7.77141, 8.39265, 8.17443, 8.30401, 7.80944, 8.39265,
              8.17443, 8.30401, 7.80944, 7.51879, 7.77141, 7.80944),
             (None,),
             (None, None, None, None, None, None, None, None, None, None, None,
              None, None)))

    def test_find_identical_traits(self):
        """
        Test `gn3.partial_correlations.find_identical_traits`.

        Given:
            - the name of a primary trait
            - the value of a primary trait
            - a sequence of names of control traits
            - a sequence of values of control traits
        When:
            - the arguments above are passed to the `find_identical_traits`
              function
        Then:
            - Return ALL trait names that have the same value when up to three
              decimal places are considered
        """
        for primn, primv, contn, contv, expected in (
                ("pt", 12.98395, ("ct0", "ct1", "ct2"),
                 (0.1234, 2.3456, 3.4567), tuple()),
                ("pt", 12.98395, ("ct0", "ct1", "ct2"),
                 (12.98354, 2.3456, 3.4567), ("pt", "ct0")),
                ("pt", 12.98395, ("ct0", "ct1", "ct2", "ct3"),
                 (0.1234, 2.3456, 0.1233, 4.5678), ("ct0", "ct2"))
        ):
            with self.subTest(
                    primary_name=primn, primary_value=primv,
                    control_names=contn, control_values=contv):
                self.assertEqual(
                    find_identical_traits(primn, primv, contn, contv), expected)