From 64ce38b45839b6305b009f6e28b0f852409e9bda Mon Sep 17 00:00:00 2001
From: Muriithi Frederick Muriuki
Date: Tue, 31 Aug 2021 10:45:11 +0300
Subject: Parse QTLReaper outputs

Issue:
https://github.com/genenetwork/gn-gemtext-threads/blob/main/topics/gn1-migration-to-gn2/clustering.gmi

* gn3/computations/qtlreaper.py: pass output files
* tests/unit/computations/data/qtlreaper/main_output_sample.txt: sample test
  data
* tests/unit/computations/data/qtlreaper/permu_output_sample.txt: sample test
  data
* tests/unit/computations/test_qtlreaper.py: add tests

  Add code to parse the QTLReaper output data files.
---
 .../data/qtlreaper/main_output_sample.txt          | 11 ++++
 .../data/qtlreaper/permu_output_sample.txt         | 27 ++++++++
 tests/unit/computations/test_qtlreaper.py          | 74 ++++++++++++++++++++++
 3 files changed, 112 insertions(+)
 create mode 100644 tests/unit/computations/data/qtlreaper/main_output_sample.txt
 create mode 100644 tests/unit/computations/data/qtlreaper/permu_output_sample.txt
 create mode 100644 tests/unit/computations/test_qtlreaper.py

(limited to 'tests/unit')

diff --git a/tests/unit/computations/data/qtlreaper/main_output_sample.txt b/tests/unit/computations/data/qtlreaper/main_output_sample.txt
new file mode 100644
index 0000000..12b11b4
--- /dev/null
+++ b/tests/unit/computations/data/qtlreaper/main_output_sample.txt
@@ -0,0 +1,11 @@
+ID	Locus	Chr	cM	Mb	LRS	Additive	pValue
+T1	rs31443144	1	1.500	3.010	0.500	-0.074	1.000
+T1	rs6269442	1	1.500	3.492	0.500	-0.074	1.000
+T1	rs32285189	1	1.630	3.511	0.500	-0.074	1.000
+T1	rs258367496	1	1.630	3.660	0.500	-0.074	1.000
+T1	rs32430919	1	1.750	3.777	0.500	-0.074	1.000
+T1	rs36251697	1	1.880	3.812	0.500	-0.074	1.000
+T1	rs30658298	1	2.010	4.431	0.500	-0.074	1.000
+T1	rs51852623	1	2.010	4.447	0.500	-0.074	1.000
+T1	rs31879829	1	2.140	4.519	0.500	-0.074	1.000
+T1	rs36742481	1	2.140	4.776	0.500	-0.074	1.000
diff --git a/tests/unit/computations/data/qtlreaper/permu_output_sample.txt b/tests/unit/computations/data/qtlreaper/permu_output_sample.txt
new file mode 100644
index 0000000..64cff07
--- /dev/null
+++ b/tests/unit/computations/data/qtlreaper/permu_output_sample.txt
@@ -0,0 +1,27 @@
+4.44174
+5.03825
+5.08167
+5.18119
+5.18578
+5.24563
+5.24619
+5.24619
+5.27961
+5.28228
+5.43903
+5.50188
+5.51694
+5.56830
+5.63874
+5.71346
+5.71936
+5.74275
+5.76764
+5.79815
+5.81671
+5.82775
+5.89659
+5.92117
+5.93396
+5.93396
+5.94957
diff --git a/tests/unit/computations/test_qtlreaper.py b/tests/unit/computations/test_qtlreaper.py
new file mode 100644
index 0000000..ec23664
--- /dev/null
+++ b/tests/unit/computations/test_qtlreaper.py
@@ -0,0 +1,74 @@
+"""Module contains tests for gn3.computations.qtlreaper"""
+import os
+from unittest import TestCase
+from gn3.computations.qtlreaper import (
+    parse_reaper_main_results, parse_reaper_permutation_results)
+
+class TestQTLReaper(TestCase):
+    """Class for testing qtlreaper interface functions."""
+
+    def test_parse_reaper_main_results(self):
+        self.assertEqual(
+            parse_reaper_main_results(
+                "tests/unit/computations/data/qtlreaper/main_output_sample.txt"),
+            [
+                {
+                    "ID": "T1", "Locus": "rs31443144", "Chr": 1, "cM": 1.500,
+                    "Mb": 3.010, "LRS": 0.500, "Additive": -0.074,
+                    "pValue": 1.000
+                },
+                {
+                    "ID": "T1", "Locus": "rs6269442", "Chr": 1, "cM": 1.500,
+                    "Mb": 3.492, "LRS": 0.500, "Additive": -0.074,
+                    "pValue": 1.000
+                },
+                {
+                    "ID": "T1", "Locus": "rs32285189", "Chr": 1, "cM": 1.630,
+                    "Mb": 3.511, "LRS": 0.500, "Additive": -0.074,
+                    "pValue": 1.000
+                },
+                {
+                    "ID": "T1", "Locus": "rs258367496", "Chr": 1, "cM": 1.630,
+                    "Mb": 3.660, "LRS": 0.500, "Additive": -0.074,
+                    "pValue": 1.000
+                },
+                {
+                    "ID": "T1", "Locus": "rs32430919", "Chr": 1, "cM": 1.750,
+                    "Mb": 3.777, "LRS": 0.500, "Additive": -0.074,
+                    "pValue": 1.000
+                },
+                {
+                    "ID": "T1", "Locus": "rs36251697", "Chr": 1, "cM": 1.880,
+                    "Mb": 3.812, "LRS": 0.500, "Additive": -0.074,
+                    "pValue": 1.000
+                },
+                {
+                    "ID": "T1", "Locus": "rs30658298", "Chr": 1, "cM": 2.010,
+                    "Mb": 4.431, "LRS": 0.500, "Additive": -0.074,
+                    "pValue": 1.000
+                },
+                {
+                    "ID": "T1", "Locus": "rs51852623", "Chr": 1, "cM": 2.010,
+                    "Mb": 4.447, "LRS": 0.500, "Additive": -0.074,
+                    "pValue": 1.000
+                },
+                {
+                    "ID": "T1", "Locus": "rs31879829", "Chr": 1, "cM": 2.140,
+                    "Mb": 4.519, "LRS": 0.500, "Additive": -0.074,
+                    "pValue": 1.000
+                },
+                {
+                    "ID": "T1", "Locus": "rs36742481", "Chr": 1, "cM": 2.140,
+                    "Mb": 4.776, "LRS": 0.500, "Additive": -0.074,
+                    "pValue": 1.000
+                }
+            ])
+
+    def test_parse_reaper_permutation_results(self):
+        self.assertEqual(
+            parse_reaper_permutation_results(
+            "tests/unit/computations/data/qtlreaper/permu_output_sample.txt"),
+            [4.44174, 5.03825, 5.08167, 5.18119, 5.18578, 5.24563, 5.24619,
+             5.24619, 5.27961, 5.28228, 5.43903, 5.50188, 5.51694, 5.56830,
+             5.63874, 5.71346, 5.71936, 5.74275, 5.76764, 5.79815, 5.81671,
+             5.82775, 5.89659, 5.92117, 5.93396, 5.93396, 5.94957])
-- 
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