From 79f931b0fbe0712954201a15278f9088fd7cdb8a Mon Sep 17 00:00:00 2001
From: BonfaceKilz
Date: Mon, 8 Mar 2021 10:52:44 +0300
Subject: Add "/gemma/k-gwa-compute/<token>"

---
 gn3/api/gemma.py | 70 ++++++++++++++++++++++++++++++++++++++++++++++++++++++++
 1 file changed, 70 insertions(+)

(limited to 'gn3/api')

diff --git a/gn3/api/gemma.py b/gn3/api/gemma.py
index a69b73e..2d1fedf 100644
--- a/gn3/api/gemma.py
+++ b/gn3/api/gemma.py
@@ -349,3 +349,73 @@ def compute_gwa_with_loco_covar(k_filename, maf, token):
             status=128,
             # use better message
             message="Metadata file non-existent!")
+
+
+@gemma.route("/k-gwa-compute/<token>", methods=["POST"])
+def compute_k_gwa(token):
+    """Given a genofile, traitfile, snpsfile, and the token, compute the k-values
+and return <hash-of-inputs>.json with a UNIQUE-ID of the job. The genofile,
+traitfile, and snpsfile are extracted from a metadata.json file. No Loco no
+covars; lmm defaults to 9!
+
+    """
+    working_dir = os.path.join(current_app.config.get("TMPDIR"), token)
+    _dict = jsonfile_to_dict(os.path.join(working_dir, "metadata.json"))
+    try:
+        genofile, phenofile, snpsfile = [
+            os.path.join(working_dir, _dict.get(x))
+            for x in ["geno", "pheno", "snps"]
+        ]
+        if not do_paths_exist([genofile, phenofile, snpsfile]):
+            raise FileNotFoundError
+        gemma_kwargs = {"g": genofile, "p": phenofile, "a": snpsfile}
+        gemma_k_cmd = generate_gemma_cmd(
+            gemma_cmd=current_app.config.get("GEMMA_"
+                                             "WRAPPER_CMD"),
+            output_dir=current_app.config.get('TMPDIR'),
+            token=token,
+            gemma_kwargs=gemma_kwargs)
+        gemma_kwargs["lmm"] = _dict.get("lmm", 9)
+        gemma_gwa_cmd = generate_gemma_cmd(
+            gemma_cmd=current_app.config.get("GEMMA_"
+                                             "WRAPPER_CMD"),
+            output_dir=current_app.config.get('TMPDIR'),
+            token=token,
+            gemma_kwargs=gemma_kwargs,
+            gemma_wrapper_kwargs={
+                "input": os.path.join(working_dir,
+                                      gemma_k_cmd.get("output_file"))
+            })
+        return jsonify(unique_id=queue_cmd(
+            conn=redis.Redis(),
+            email=(request.get_json() or {}).get('email'),
+            job_queue=current_app.config.get("REDIS_JOB_QUEUE"),
+            cmd=(f"{gemma_k_cmd.get('gemma_cmd')} && "
+                 f"{gemma_gwa_cmd.get('gemma_cmd')}")),
+                       status="queued",
+                       output_file=gemma_gwa_cmd.get("output_file"))
+    # pylint: disable=W0703
+    except Exception:
+        return jsonify(
+            status=128,
+            # use better message
+            message="Metadata file non-existent!")
+            gemma_cmd=current_app.config.get("GEMMA_"
+                                             "WRAPPER_CMD"),
+            output_dir=current_app.config.get('TMPDIR'),
+            token=token,
+            gemma_kwargs=gemma_kwargs)
+        return jsonify(unique_id=queue_cmd(
+            conn=redis.Redis(),
+            email=(request.get_json() or {}).get('email'),
+            job_queue=current_app.config.get("REDIS_JOB_QUEUE"),
+            cmd=(f"{gemma_k_cmd.get('gemma_cmd')} && "
+                 f"{gemma_gwa_cmd.get('gemma_cmd')}")),
+                       status="queued",
+                       output_file=gemma_gwa_cmd.get("output_file"))
+    # pylint: disable=W0703
+    except Exception:
+        return jsonify(
+            status=128,
+            # use better message
+            message="Metadata file non-existent!")
-- 
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