diff options
Diffstat (limited to 'gn3')
-rw-r--r-- | gn3/db/genotypes.py | 37 |
1 files changed, 37 insertions, 0 deletions
diff --git a/gn3/db/genotypes.py b/gn3/db/genotypes.py index be0dfc2..8710d2e 100644 --- a/gn3/db/genotypes.py +++ b/gn3/db/genotypes.py @@ -106,3 +106,40 @@ def parse_genotype_header(line: str, parlist = tuple()): ("mb_column", None if not Mbmap else items.index("Mb")), ("prgy", prgy), ("nprgy", len(prgy))) + +def parse_genotype_data_line(line: str, geno_obj: dict, parlist: list): + """ + Parse a data line in a genotype file + + DESCRIPTION: + Reworks + https://github.com/genenetwork/genenetwork1/blob/master/web/webqtl/utility/gen_geno_ob.py#L143-L190 + """ + marker_row = [item.strip() for item in line.split("\t")] + geno_table = { + geno_obj["mat"]: -1, geno_obj["pat"]: 1, geno_obj["het"]: 0, + geno_obj["unk"]: "U" + } + start_pos = 4 if geno_obj["Mbmap"] else 3 + if len(parlist) > 0: + start_pos = start_pos + 2 + + alleles = marker_row[start_pos:] + genotype = tuple( + (geno_table[allele] if allele in geno_table.keys() else "U") + for allele in alleles) + if len(parlist) > 0: + genotype = (-1, 1) + genotype + try: + cM = float(geno_obj["cm_column"]) + except: + if geno_obj["Mbmap"]: + cM = float(geno_obj["mb_column"]) + else: + cM = 0 + return ( + ("chr", marker_row[0]), + ("name", marker_row[1]), + ("cM", cM), + ("Mb", float(geno_obj["mb_column"]) if geno_obj["Mbmap"] else None), + ("genotype", genotype)) |