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+"""
+This module deals with partial correlations.
+
+It is an attempt to migrate over the partial correlations feature from
+GeneNetwork1.
+"""
+
+from functools import reduce
+from typing import Any, Sequence
+
+def control_samples(controls: Sequence[dict], sampleslist: Sequence[str]):
+ """
+ Fetches data for the control traits.
+
+ This migrates `web/webqtl/correlation/correlationFunction.controlStrain` in
+ GN1, with a few modifications to the arguments passed in.
+
+ PARAMETERS:
+ controls: A map of sample names to trait data. Equivalent to the `cvals`
+ value in the corresponding source function in GN1.
+ sampleslist: A list of samples. Equivalent to `strainlst` in the
+ corresponding source function in GN1
+ """
+ def __process_control__(trait_data):
+ def __process_sample__(acc, sample):
+ if sample in trait_data["data"].keys():
+ sample_item = trait_data["data"][sample]
+ val = sample_item["value"]
+ if val is not None:
+ return (
+ acc[0] + (sample,),
+ acc[1] + (val,),
+ acc[2] + (sample_item["variance"],))
+ return acc
+ return reduce(
+ __process_sample__, sampleslist, (tuple(), tuple(), tuple()))
+
+ return reduce(
+ lambda acc, item: (
+ acc[0] + (item[0],),
+ acc[1] + (item[1],),
+ acc[2] + (item[2],),
+ acc[3] + (len(item[0]),),
+ ),
+ [__process_control__(trait_data) for trait_data in controls],
+ (tuple(), tuple(), tuple(), tuple()))
+
+def dictify_by_samples(samples_vals_vars: Sequence[Sequence]) -> Sequence[dict]:
+ """
+ Build a sequence of dictionaries from a sequence of separate sequences of
+ samples, values and variances.
+
+ This is a partial migration of
+ `web.webqtl.correlation.correlationFunction.fixStrains` function in GN1.
+ This implementation extracts code that will find common use, and that will
+ find use in more than one place.
+ """
+ return tuple(
+ {
+ sample: {"sample_name": sample, "value": val, "variance": var}
+ for sample, val, var in zip(*trait_line)
+ } for trait_line in zip(*(samples_vals_vars[0:3])))
+
+def fix_samples(primary_trait: dict, control_traits: Sequence[dict]) -> Sequence[Sequence[Any]]:
+ """
+ Corrects sample_names, values and variance such that they all contain only
+ those samples that are common to the reference trait and all control traits.
+
+ This is a partial migration of the
+ `web.webqtl.correlation.correlationFunction.fixStrain` function in GN1.
+ """
+ primary_samples = tuple(
+ present[0] for present in
+ ((sample, all(sample in control.keys() for control in control_traits))
+ for sample in primary_trait.keys())
+ if present[1])
+ control_vals_vars: tuple = reduce(
+ lambda acc, x: (acc[0] + (x[0],), acc[1] + (x[1],)),
+ ((item["value"], item["variance"])
+ for sublist in [tuple(control.values()) for control in control_traits]
+ for item in sublist),
+ (tuple(), tuple()))
+ return (
+ primary_samples,
+ tuple(primary_trait[sample]["value"] for sample in primary_samples),
+ control_vals_vars[0],
+ tuple(primary_trait[sample]["variance"] for sample in primary_samples),
+ control_vals_vars[1])