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authorBonfaceKilz2021-07-29 22:08:01 +0300
committerBonfaceKilz2021-07-29 22:08:01 +0300
commit8d83ba7298c33e54ab204effe2a4241ce848add9 (patch)
treef6ff2fd64cd288d75af4900cb7b2cd984f598ce0 /gn3/db/traits.py
parent651515eb88cb5675434ff068ad19edd0c4c0e858 (diff)
parent2ccbf1844afe352e23af7ff958ec2b0694cd87ea (diff)
downloadgenenetwork3-8d83ba7298c33e54ab204effe2a4241ce848add9.tar.gz
Merge branch 'main' into Feature/Update-db-from-csv-data
Diffstat (limited to 'gn3/db/traits.py')
-rw-r--r--gn3/db/traits.py159
1 files changed, 158 insertions, 1 deletions
diff --git a/gn3/db/traits.py b/gn3/db/traits.py
index a77e6a1..ae1939a 100644
--- a/gn3/db/traits.py
+++ b/gn3/db/traits.py
@@ -1,5 +1,5 @@
"""This class contains functions relating to trait data manipulation"""
-from typing import Any, Union
+from typing import Any, Dict, Union
def get_trait_csv_sample_data(conn: Any,
@@ -75,3 +75,160 @@ def update_sample_data(conn: Any,
updated_n_strains: int = cursor.rowcount
return (updated_strains, updated_published_data,
updated_se_data, updated_n_strains)
+
+
+def retrieve_trait_dataset_name(
+ trait_type: str, threshold: int, name: str, connection: Any):
+ """
+ Retrieve the name of a trait given the trait's name
+
+ This is extracted from the `webqtlDataset.retrieveName` function as is
+ implemented at
+ https://github.com/genenetwork/genenetwork1/blob/master/web/webqtl/base/webqtlDataset.py#L140-L169
+ """
+ columns = "Id, Name, FullName, ShortName{}".format(
+ ", DataScale" if trait_type == "ProbeSet" else "")
+ query = (
+ "SELECT {columns} "
+ "FROM {trait_type}Freeze "
+ "WHERE "
+ "public > %(threshold)s "
+ "AND "
+ "(Name = %(name)s OR FullName = %(name)s OR ShortName = %(name)s)").format(
+ columns=columns, trait_type=trait_type)
+ with connection.cursor() as cursor:
+ cursor.execute(query, {"threshold": threshold, "name": name})
+ return cursor.fetchone()
+
+PUBLISH_TRAIT_INFO_QUERY = (
+ "SELECT "
+ "PublishXRef.Id, Publication.PubMed_ID, "
+ "Phenotype.Pre_publication_description, "
+ "Phenotype.Post_publication_description, "
+ "Phenotype.Original_description, "
+ "Phenotype.Pre_publication_abbreviation, "
+ "Phenotype.Post_publication_abbreviation, "
+ "Phenotype.Lab_code, Phenotype.Submitter, Phenotype.Owner, "
+ "Phenotype.Authorized_Users, CAST(Publication.Authors AS BINARY), "
+ "Publication.Title, Publication.Abstract, Publication.Journal, "
+ "Publication.Volume, Publication.Pages, Publication.Month, "
+ "Publication.Year, PublishXRef.Sequence, Phenotype.Units, "
+ "PublishXRef.comments "
+ "FROM "
+ "PublishXRef, Publication, Phenotype, PublishFreeze "
+ "WHERE "
+ "PublishXRef.Id = %(trait_name)s AND "
+ "Phenotype.Id = PublishXRef.PhenotypeId AND "
+ "Publication.Id = PublishXRef.PublicationId AND "
+ "PublishXRef.InbredSetId = PublishFreeze.InbredSetId AND "
+ "PublishFreeze.Id =%(trait_dataset_id)s")
+
+
+def retrieve_publish_trait_info(trait_data_source: Dict[str, Any], conn: Any):
+ """Retrieve trait information for type `Publish` traits.
+
+ https://github.com/genenetwork/genenetwork1/blob/master/web/webqtl/base/webqtlTrait.py#L399-L421"""
+ with conn.cursor() as cursor:
+ cursor.execute(
+ PUBLISH_TRAIT_INFO_QUERY,
+ {
+ k:v for k, v in trait_data_source.items()
+ if k in ["trait_name", "trait_dataset_id"]
+ })
+ return cursor.fetchone()
+
+PROBESET_TRAIT_INFO_QUERY = (
+ "SELECT "
+ "ProbeSet.name, ProbeSet.symbol, ProbeSet.description, "
+ "ProbeSet.probe_target_description, ProbeSet.chr, ProbeSet.mb, "
+ "ProbeSet.alias, ProbeSet.geneid, ProbeSet.genbankid, ProbeSet.unigeneid, "
+ "ProbeSet.omim, ProbeSet.refseq_transcriptid, ProbeSet.blatseq, "
+ "ProbeSet.targetseq, ProbeSet.chipid, ProbeSet.comments, "
+ "ProbeSet.strand_probe, ProbeSet.strand_gene, "
+ "ProbeSet.probe_set_target_region, ProbeSet.proteinid, "
+ "ProbeSet.probe_set_specificity, ProbeSet.probe_set_blat_score, "
+ "ProbeSet.probe_set_blat_mb_start, ProbeSet.probe_set_blat_mb_end, "
+ "ProbeSet.probe_set_strand, ProbeSet.probe_set_note_by_rw, "
+ "ProbeSet.flag "
+ "FROM "
+ "ProbeSet, ProbeSetFreeze, ProbeSetXRef "
+ "WHERE "
+ "ProbeSetXRef.ProbeSetFreezeId = ProbeSetFreeze.Id AND "
+ "ProbeSetXRef.ProbeSetId = ProbeSet.Id AND "
+ "ProbeSetFreeze.Name = %(trait_dataset_name)s AND "
+ "ProbeSet.Name = %(trait_name)s")
+
+def retrieve_probeset_trait_info(trait_data_source: Dict[str, Any], conn: Any):
+ """Retrieve trait information for type `ProbeSet` traits.
+
+ https://github.com/genenetwork/genenetwork1/blob/master/web/webqtl/base/webqtlTrait.py#L424-L435"""
+ with conn.cursor() as cursor:
+ cursor.execute(
+ PROBESET_TRAIT_INFO_QUERY,
+ {
+ k:v for k, v in trait_data_source.items()
+ if k in ["trait_name", "trait_dataset_name"]
+ })
+ return cursor.fetchone()
+
+GENO_TRAIT_INFO_QUERY = (
+ "SELECT "
+ "Geno.name, Geno.chr, Geno.mb, Geno.source2, Geno.sequence "
+ "FROM "
+ "Geno, GenoFreeze, GenoXRef "
+ "WHERE "
+ "GenoXRef.GenoFreezeId = GenoFreeze.Id AND GenoXRef.GenoId = Geno.Id AND "
+ "GenoFreeze.Name = %(trait_dataset_name)s AND Geno.Name = %(trait_name)s")
+
+def retrieve_geno_trait_info(trait_data_source: Dict[str, Any], conn: Any):
+ """Retrieve trait information for type `Geno` traits.
+
+ https://github.com/genenetwork/genenetwork1/blob/master/web/webqtl/base/webqtlTrait.py#L438-L449"""
+ with conn.cursor() as cursor:
+ cursor.execute(
+ GENO_TRAIT_INFO_QUERY,
+ {
+ k:v for k, v in trait_data_source.items()
+ if k in ["trait_name", "trait_dataset_name"]
+ })
+ return cursor.fetchone()
+
+TEMP_TRAIT_INFO_QUERY = (
+ "SELECT name, description FROM Temp "
+ "WHERE Name = %(trait_name)s")
+
+def retrieve_temp_trait_info(trait_data_source: Dict[str, Any], conn: Any):
+ """Retrieve trait information for type `Temp` traits.
+
+ https://github.com/genenetwork/genenetwork1/blob/master/web/webqtl/base/webqtlTrait.py#L450-452"""
+ with conn.cursor() as cursor:
+ cursor.execute(
+ TEMP_TRAIT_INFO_QUERY,
+ {
+ k:v for k, v in trait_data_source.items()
+ if k in ["trait_name"]
+ })
+ return cursor.fetchone()
+
+def retrieve_trait_info(
+ trait_type: str, trait_name: str, trait_dataset_id: int,
+ trait_dataset_name: str, conn: Any):
+ """Retrieves the trait information.
+
+ https://github.com/genenetwork/genenetwork1/blob/master/web/webqtl/base/webqtlTrait.py#L397-L456
+
+ This function, or the dependent functions, might be incomplete as they are
+ currently."""
+ trait_info_function_table = {
+ "Publish": retrieve_publish_trait_info,
+ "ProbeSet": retrieve_probeset_trait_info,
+ "Geno": retrieve_geno_trait_info,
+ "Temp": retrieve_temp_trait_info
+ }
+ return trait_info_function_table[trait_type](
+ {
+ "trait_name": trait_name,
+ "trait_dataset_id": trait_dataset_id,
+ "trait_dataset_name":trait_dataset_name
+ },
+ conn)