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authorPjotr Prins2023-03-13 11:56:24 +0100
committerPjotr Prins2023-03-13 11:56:24 +0100
commit6197e350b2696ab77f76f3b29dfaef253961c241 (patch)
treec3528118a39f1d8a4043b9e8132fc8b8d74f6573 /docs/performance
parent8d26fd22a01950ef2f00626649639a1ec00c55ce (diff)
downloadgenenetwork3-6197e350b2696ab77f76f3b29dfaef253961c241.tar.gz
Move doc to issue tracker
Diffstat (limited to 'docs/performance')
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-* Slow ProbeSetData SQL query
-
-** The case
-
-We were looking to optimize a query for correlations. On Penguin2 (standard
-drives, RAID5) the query took 1 hour. On Tux01 (solid state NVME) it took 6
-minutes. Adding an index for StrainId (see explorations below) reduced that
-query to 3 minutes - which is kinda acceptable. The real problem, however is
-that this is a quadratic search - so it will get worse quickly - and we need
-to solve it. This table has doubled in size in the last 5 years.
-
-So what does ProbeSetData contain?
-
-#+BEGIN_SRC SQL
-select * from ProbeSetData limit 5;
-+----+----------+-------+
-| Id | StrainId | value |
-+----+----------+-------+
-| 1 | 1 | 5.742 |
-| 1 | 2 | 5.006 |
-| 1 | 3 | 6.079 |
-| 1 | 4 | 6.414 |
-| 1 | 5 | 4.885 |
-+----+----------+-------+
-#+END_SRC
-
-You can see Id is sectioned in the file (and there are not that many Ids) but
-StrainId is *distributed* through the database file and some 'StrainIds' match
-many data points. Id stands for Dataset (item) and StrainId really means
-measurement type or trait measured(!)
-
-Our query looked for 1,236,088 measurement distributed over a 53Gb file (and
-an even larger index file). Turns out the full table is read many many times
-over for one particular query pivoting on strainid...
-
-We have the following options:
-
-1. Reorder the table
-2. Use column based storage
-3. Use compression
-4. Use a different storage layout
-
-*** Reorder the table
-
-We could reorder the table on StrainID which would make this search much faster
-but it would many common (dataset) queries slower. So, that is not a great
-idea. One thing we could try is add a copy of the first table. Not exactly
-elegant but a quick fix for sure. We'll need an embedded procedure to keep it
-up-to-data.
-
-*** Use column based storage
-
-Column-based storage works when you need a subset of the data in the table. In
-this case it won't help much because, even though the pivot itself would be
-faster, we still traverse all data to get IDs and values.
-
-*** Use compression
-
-Compression reduces the size on disk and may be beneficial. Real life metrics
-on the internet don't show that much improvement, but we could try native
-compression and/or ZFS.
-
-*** Use a different storage layout
-
-My prediction is that we can not get around this.
-
-** Result
-
-The final query is shown at the bottom of 'Exploration'. It takes 2 minutes
-on Penguin2 and Tux01. Essentially I took out the joins (which parsed the same
-table repeatedly) and added an index. The trick is to keep minimizing the query.
-
-The 2 minute query will do for now and it probably is no longer quadratic.
-
-We can probably improve things in the future by changing the way ProbeSetData
-is stored.
-
-
-** Exploration
-
-In the following steps I reduce the complex case to a simple case explaining
-the performance bottleneck we are seeing today. I did not add comments, but
-you can see what I did.
-
-#+BEGIN_SRC SQL
-MariaDB [db_webqtl]> select * from ProbeSetXRef limit 2;
-+------------------+------------+--------+------------+--------------------+------------+------------------+---------------------+------------+------------------+--------+--------------------+------+
-| ProbeSetFreezeId | ProbeSetId | DataId | Locus_old | LRS_old | pValue_old | mean | se | Locus | LRS | pValue | additive | h2 |
-+------------------+------------+--------+------------+--------------------+------------+------------------+---------------------+------------+------------------+--------+--------------------+------+
-| 1 | 1 | 1 | 10.095.400 | 13.3971627898894 | 0.163 | 5.48794285714286 | 0.08525787814808819 | rs13480619 | 12.590069931048 | 0.269 | -0.28515625 | NULL |
-| 1 | 2 | 2 | D15Mit189 | 10.042057464356201 | 0.431 | 9.90165714285714 | 0.0374686634976217 | rs29535974 | 10.5970737900941 | 0.304 | -0.116783333333333 | NULL |
-+------------------+------------+--------+------------+--------------------+------------+------------------+---------------------+------------+------------------+--------+--------------------+------+
-2 rows in set (0.001 sec)
-#+END_SRC
-
-#+BEGIN_SRC SQL
-MariaDB [db_webqtl]> SELECT ProbeSet.Name,T4.value FROM (ProbeSet, ProbeSetXRef, ProbeSetFreeze) left join ProbeSetData as T4 on T4.Id = ProbeSetXRef.DataId
- -> and T4.StrainId=4
- -> limit 5;
-+------+-------+
-| Name | value |
-+------+-------+
-| NULL | 6.414 |
-| NULL | 6.414 |
-| NULL | 6.414 |
-| NULL | 6.414 |
-| NULL | 6.414 |
-+------+-------+
-#+END_SRC
-
-
-#+BEGIN_SRC SQL
-MariaDB [db_webqtl]> SELECT ProbeSet.Name,T4.value FROM (ProbeSet, ProbeSetXRef)
- left join ProbeSetData as T4 on T4.StrainId=4 and T4.Id = ProbeSetXRef.DataId
- WHERE ProbeSet.Id = ProbeSetXRef.ProbeSetId order by ProbeSet.Id limit 5;
-+-----------+-------+
-| Name | value |
-+-----------+-------+
-| 100001_at | 6.414 |
-| 100001_at | 6.414 |
-| 100001_at | 6.414 |
-| 100001_at | 8.414 |
-| 100001_at | 8.414 |
-+-----------+-------+
-5 rows in set (20.064 sec)
-#+END_SRC SQL
-
-#+BEGIN_SRC SQL
-MariaDB [db_webqtl]> SELECT ProbeSet.Name,T4.value,T5.value FROM (ProbeSet, ProbeSetXRef, ProbeSetFreeze)
-left join ProbeSetData as T4 on T4.Id = ProbeSetXRef.DataId and T4.StrainId=4
-left join ProbeSetData as T5 on T5.Id = ProbeSetXRef.DataId and T5.StrainId=5
-WHERE ProbeSetXRef.ProbeSetFreezeId = ProbeSetFreeze.Id
-and ProbeSetFreeze.Name = 'UMUTAffyExon_0209_RMA'
-and ProbeSet.Id = ProbeSetXRef.ProbeSetId
-order by ProbeSet.Id limit 5;
-
-+---------+---------+
-| Name | value |
-+---------+---------+
-| 4331726 | 5.52895 |
-| 5054239 | 6.29465 |
-| 4642578 | 9.13706 |
-| 4398221 | 6.77672 |
-| 5543360 | 4.30016 |
-+---------+---------+
-#+END_SRC
-
-#+BEGIN_SRC SQL
-SELECT ProbeSet.Name,T4.value FROM (ProbeSet, ProbeSetXRef, ProbeSetFreeze)
-left join ProbeSetData as T4 on T4.Id = ProbeSetXRef.DataId and T4.StrainId=4
-WHERE ProbeSetXRef.ProbeSetFreezeId = ProbeSetFreeze.Id
-and ProbeSetFreeze.Name = 'UMUTAffyExon_0209_RMA'
-and ProbeSet.Id = ProbeSetXRef.ProbeSetId
-order by ProbeSet.Id ;
-
-1236087 rows in set (19.173 sec)
-#+END_SRC
-
-#+BEGIN_SRC SQL
-SELECT ProbeSet.Name,T4.value FROM (ProbeSet, ProbeSetXRef, ProbeSetFreeze)
-left join ProbeSetData as T4 on T4.StrainId=4 and T4.Id = ProbeSetXRef.DataId
-WHERE ProbeSetXRef.ProbeSetFreezeId = ProbeSetFreeze.Id
-and ProbeSetFreeze.Name = 'UMUTAffyExon_0209_RMA'
-and ProbeSet.Id = ProbeSetXRef.ProbeSetId
-order by ProbeSet.Id ;
-
-1236087 rows in set (19.173 sec)
-#+END_SRC
-
-#+BEGIN_SRC SQL
-SELECT ProbeSet.Name FROM (ProbeSet, ProbeSetXRef, ProbeSetFreeze)
-WHERE ProbeSetXRef.ProbeSetFreezeId = ProbeSetFreeze.Id
-and ProbeSetFreeze.Name = 'UMUTAffyExon_0209_RMA'
-and ProbeSet.Id = ProbeSetXRef.ProbeSetId
-order by ProbeSet.Id ;
-#+END_SRC
-
-Find all the probeset 'names' (probe sequence included) for one dataset:
-
-#+BEGIN_SRC SQL
-SELECT count(DISTINCT ProbeSet.Name) FROM (ProbeSet, ProbeSetXRef, ProbeSetFreeze) WHERE ProbeSetXRef.ProbeSetFreezeId = ProbeSetFreeze.Id and ProbeSetFreeze.Name = 'UMUTAffyExon_0209_RMA' and ProbeSet.Id = ProbeSetXRef.ProbeSetId order by ProbeSet.Id;
-+-------------------------------+
-| count(DISTINCT ProbeSet.Name) |
-+-------------------------------+
-| 1236087 |
-+-------------------------------+
-#+END_SRC
-
-Now for each of those probesets:
-
-#+BEGIN_SRC SQL
-SELECT ProbeSet.Name,T4.value FROM (ProbeSet, ProbeSetXRef)
-left join ProbeSetData as T4 on T4.StrainId=4 and T4.Id = ProbeSetXRef.DataId
-WHERE ProbeSet.Id = ProbeSetXRef.ProbeSetId
-order by ProbeSet.Id limit 5;
-#+END_SRC
-
-ProbeSetXRef contains the p-values:
-
-#+BEGIN_SRC SQL
-select * from ProbeSetXRef limit 5;
-+------------------+------------+--------+------------+--------------------+------------+-------------------+---------------------+------------+------------------+--------+--------------------+------+
-| ProbeSetFreezeId | ProbeSetId | DataId | Locus_old | LRS_old | pValue_old | mean | se | Locus | LRS | pValue | additive | h2 |
-+------------------+------------+--------+------------+--------------------+------------+-------------------+---------------------+------------+------------------+--------+--------------------+------+
-| 1 | 1 | 1 | 10.095.400 | 13.3971627898894 | 0.163 | 5.48794285714286 | 0.08525787814808819 | rs13480619 | 12.590069931048 | 0.269 | -0.28515625 | NULL |
-| 1 | 2 | 2 | D15Mit189 | 10.042057464356201 | 0.431 | 9.90165714285714 | 0.0374686634976217 | rs29535974 | 10.5970737900941 | 0.304 | -0.116783333333333 | NULL |
-#+END_SRC
-
-
-#+BEGIN_SRC SQL
-SELECT count(T4.value) FROM (ProbeSet, ProbeSetXRef)
-left join ProbeSetData as T4 on T4.StrainId=4 and T4.Id = ProbeSetXRef.DataId
-WHERE ProbeSet.Id = ProbeSetXRef.ProbeSetId ;
-#+END_SRC
-
-
-#+BEGIN_SRC SQL
-SELECT count(T4.value) FROM (ProbeSet, ProbeSetXRef) left join ProbeSetData as T4 on T4.StrainId=4 limit 5;
-#+END_SRC
-
-#+BEGIN_SRC SQL
-select value from (ProbeSetData) where StrainId=4 limit 5;
-#+END_SRC
-
-So, this is the sloooow baby:
-
-#+BEGIN_SRC SQL
-select count(id) from (ProbeSetData) where StrainId=4;
-
-| ProbeSetData | 0 | DataId | 2 | StrainId | A | 4852908856 | NULL | NULL | | BTREE | | |
-
--rw-rw---- 1 mysql mysql 53G Mar 3 23:49 ProbeSetData.MYD
--rw-rw---- 1 mysql mysql 66G Mar 4 03:00 ProbeSetData.MYI
-#+END_SRC
-
-#+BEGIN_SRC SQL
-create index strainid on ProbeSetData(StrainId);
-Stage: 1 of 2 'Copy to tmp table' 8.77% of stage done
-Stage: 2 of 2 'Enabling keys' 0% of stage done
-#+END_SRC
-
-#+BEGIN_SRC SQL
-MariaDB [db_webqtl]> create index strainid on ProbeSetData(StrainId);
-Query OK, 5111384047 rows affected (2 hours 56 min 25.807 sec)
-Records: 5111384047 Duplicates: 0 Warnings: 0
-#+END_SRC
-
-#+BEGIN_SRC SQL
-MariaDB [db_webqtl]> select count(id) from (ProbeSetData) where StrainId=4;
-
-+-----------+
-| count(id) |
-+-----------+
-| 14267545 |
-+-----------+
-1 row in set (19.707 sec)
-#+END_SRC
-
-
-#+BEGIN_SRC SQL
-MariaDB [db_webqtl]> select count(*) from ProbeSetData where strainid = 140;
-+----------+
-| count(*) |
-+----------+
-| 10717771 |
-+----------+
-1 row in set (10.161 sec)
-#+END_SRC
-
-#+BEGIN_SRC SQL
-MariaDB [db_webqtl]> select count(*) from ProbeSetData where strainid = 140 and id=4;
-+----------+
-| count(*) |
-+----------+
-| 0 |
-+----------+
-1 row in set (0.000 sec)
-#+END_SRC
-
-#+BEGIN_SRC SQL
-MariaDB [db_webqtl]> select count(*) from ProbeSetData where strainid = 4 and id=4;
-+----------+
-| count(*) |
-+----------+
-| 1 |
-+----------+
-1 row in set (0.000 sec)
-#+END_SRC
-
-
-#+BEGIN_SRC SQL
-select id from ProbeSetFreeze where id=1;
-
-WHERE ProbeSetXRef.ProbeSetFreezeId = ProbeSetFreeze.Id
-and ProbeSetFreeze.Name = 'UMUTAffyExon_0209_RMA'
-and ProbeSet.Id = ProbeSetXRef.ProbeSetId
-order by ProbeSet.Id limit 5;
-#+END_SRC
-
-#+BEGIN_SRC SQL
-select count(ProbeSetId) from ProbeSetXRef where ProbeSetFreezeId=1;
-+-------------------+
-| count(ProbeSetId) |
-+-------------------+
-| 12422 |
-+-------------------+
-1 row in set (0.006 sec)
-#+END_SRC
-
-
-#+BEGIN_SRC SQL
-select count(ProbeSetId) from (ProbeSetXRef,ProbeSetFreeze) where
-ProbeSetXRef.ProbeSetFreezeId = ProbeSetFreeze.Id
-and ProbeSetFreeze.Name = 'UMUTAffyExon_0209_RMA';
-#+END_SRC
-
-#+BEGIN_SRC SQL
-MariaDB [db_webqtl]> select count(ProbeSetId) from (ProbeSetXRef,ProbeSetFreeze) where
- -> ProbeSetXRef.ProbeSetFreezeId = ProbeSetFreeze.Id
- -> and ProbeSetFreeze.Name = 'UMUTAffyExon_0209_RMA';
-+-------------------+
-| count(ProbeSetId) |
-+-------------------+
-| 1236087 |
-+-------------------+
-1 row in set (0.594 sec)
-#+END_SRC
-
-ProbeSetXRef.ProbeSetFreezeId is 206, so
-
-#+BEGIN_SRC SQL
-MariaDB [db_webqtl]> select count(ProbeSetId) from (ProbeSetXRef) where ProbeSetXRef.ProbeSetFreezeId = 206;
-+-------------------+
-| count(ProbeSetId) |
-+-------------------+
-| 1236087 |
-+-------------------+
-1 row in set (0.224 sec)
-#+END_SRC
-
-#+BEGIN_SRC SQL
-MariaDB [db_webqtl]> select count(*) from ProbeSetData where strainid = 1 and id=4;
-+----------+
-| count(*) |
-+----------+
-| 1 |
-+----------+
-1 row in set (0.000 sec)
-#+END_SRC
-
-Now this query is fast because it traverses the ProbeSetData table only once and uses id as a starting point:
-
-#+BEGIN_SRC SQL
-MariaDB [db_webqtl]> select count(*) from (ProbeSetData,ProbeSetXRef) where ProbeSetXRef.ProbeSetFreezeId = 206 and id=ProbeSetId;
-+----------+
-| count(*) |
-+----------+
-| 10699448 |
-+----------+
-1 row in set (4.429 sec)
-#+END_SRC
-
-#+BEGIN_SRC SQL
-select id,strainid,value from (ProbeSetData,ProbeSetXRef) where
- ProbeSetXRef.ProbeSetFreezeId = 206 and id=ProbeSetId
-limit 5;
-+--------+----------+-------+
-| id | strainid | value |
-+--------+----------+-------+
-| 225088 | 1 | 7.33 |
-| 225088 | 2 | 7.559 |
-| 225088 | 3 | 7.84 |
-| 225088 | 4 | 7.835 |
-| 225088 | 5 | 7.652 |
-+--------+----------+-------+
-5 rows in set (0.001 sec)
-#+END_SRC
-
-
-#+BEGIN_SRC SQL
-select id,strainid,value from (ProbeSetData,ProbeSetXRef) where ProbeSetXRef.ProbeSetFreezeId = 206 and id=ProbeSetId and strainid=4 limit 5;
-+--------+----------+-------+
-| id | strainid | value |
-+--------+----------+-------+
-| 225088 | 4 | 7.835 |
-| 225089 | 4 | 9.595 |
-| 225090 | 4 | 8.982 |
-| 225091 | 4 | 8.153 |
-| 225092 | 4 | 7.111 |
-+--------+----------+-------+
-5 rows in set (0.000 sec)
-#+END_SRC
-
-#+BEGIN_SRC SQL
-select ProbeSet.name,strainid,probesetfreezeid,value from (ProbeSet,ProbeSetData,ProbeSetFreeze,ProbeSetXRef)
-where ProbeSetData.id=ProbeSetId
- and (strainid=4 or strainid=5)
- and ProbeSetXRef.ProbeSetFreezeId = ProbeSetFreeze.Id
- and ProbeSet.Id = ProbeSetXRef.ProbeSetId
- and ProbeSetFreeze.Name = 'UMUTAffyExon_0209_RMA'
-limit 5;
-+---------+----------+------------------+-------+
-| name | strainid | probesetfreezeid | value |
-+---------+----------+------------------+-------+
-| 4331726 | 4 | 206 | 7.835 |
-| 5054239 | 4 | 206 | 9.595 |
-| 4642578 | 4 | 206 | 8.982 |
-| 4398221 | 4 | 206 | 8.153 |
-| 5543360 | 4 | 206 | 7.111 |
-+---------+----------+------------------+-------+
-5 rows in set (2.174 sec)
-#+END_SRC
-
-No more joins and super fast!!
-
-#+BEGIN_SRC SQL
-SELECT ProbeSet.Name,T4.StrainID,Probesetfreezeid,T4.value
-FROM (ProbeSet, ProbeSetXRef, ProbeSetFreeze)
- left join ProbeSetData as T4 on T4.StrainId=4 and T4.Id = ProbeSetXRef.DataId
-WHERE ProbeSetXRef.ProbeSetFreezeId = ProbeSetFreeze.Id
- and ProbeSetFreeze.Name = 'UMUTAffyExon_0209_RMA'
- and ProbeSet.Id = ProbeSetXRef.ProbeSetId
-order by ProbeSet.Id limit 5;
-+---------+----------+------------------+---------+
-| Name | StrainID | Probesetfreezeid | value |
-+---------+----------+------------------+---------+
-| 4331726 | 4 | 206 | 5.52895 |
-| 5054239 | 4 | 206 | 6.29465 |
-| 4642578 | 4 | 206 | 9.13706 |
-| 4398221 | 4 | 206 | 6.77672 |
-| 5543360 | 4 | 206 | 4.30016 |
-+---------+----------+------------------+---------+
-5 rows in set (0.000 sec)
-#+END_SRC
-
-The difference is the use of ProbeSetId and DataId in ProbeSetFreeze
-
-: left join ProbeSetData as T4 on T4.StrainId=4 and T4.Id = ProbeSetXRef.DataId
-
-#+BEGIN_SRC SQL
-select ProbeSetData.id,ProbeSet.name,strainid,probesetfreezeid,value from (ProbeSet,ProbeSetData,ProbeSetFreeze,ProbeSetXRef)
-where ProbeSetData.id=ProbeSetId
- and (strainid=4 or strainid=5)
- and ProbeSetXRef.ProbeSetFreezeId = ProbeSetFreeze.Id
- and ProbeSet.Id = ProbeSetXRef.ProbeSetId
- and ProbeSetFreeze.Name = 'UMUTAffyExon_0209_RMA'
-limit 5;
-+---------+----------+------------------+-------+
-| name | strainid | probesetfreezeid | value |
-+---------+----------+------------------+-------+
-| 4331726 | 4 | 206 | 7.835 |
-| 5054239 | 4 | 206 | 9.595 |
-| 4642578 | 4 | 206 | 8.982 |
-| 4398221 | 4 | 206 | 8.153 |
-| 5543360 | 4 | 206 | 7.111 |
-+---------+----------+------------------+-------+
-5 rows in set (2.174 sec)
-#+END_SRC
-
-
-#+BEGIN_SRC SQL
-MariaDB [db_webqtl]> select ProbeSetData.id,ProbeSet.name,strainid,probesetfreezeid,value from (ProbeSet,ProbeSetData,ProbeSetFreeze,ProbeSetXRef)
- where ProbeSetData.id=ProbeSetId
- and (strainid=4 or strainid=5)
- and ProbeSetXRef.ProbeSetFreezeId = ProbeSetFreeze.Id
- and ProbeSet.Id = ProbeSetXRef.ProbeSetId
- and ProbeSetFreeze.Name = 'UMUTAffyExon_0209_RMA'
- limit 5;
-+--------+---------+----------+------------------+-------+
-| id | name | strainid | probesetfreezeid | value |
-+--------+---------+----------+------------------+-------+
-| 225088 | 4331726 | 4 | 206 | 7.835 |
-| 225089 | 5054239 | 4 | 206 | 9.595 |
-| 225090 | 4642578 | 4 | 206 | 8.982 |
-| 225091 | 4398221 | 4 | 206 | 8.153 |
-| 225092 | 5543360 | 4 | 206 | 7.111 |
-+--------+---------+----------+------------------+-------+
-5 rows in set (2.085 sec)
-#+END_SRC
-
-
-#+BEGIN_SRC SQL
-MariaDB [db_webqtl]> SELECT T4.id,ProbeSet.Name,T4.StrainID,Probesetfreezeid,T4.value
- -> FROM (ProbeSet, ProbeSetXRef, ProbeSetFreeze)
- -> left join ProbeSetData as T4 on T4.StrainId=4 and T4.Id = ProbeSetXRef.DataId
- -> WHERE ProbeSetXRef.ProbeSetFreezeId = ProbeSetFreeze.Id
- -> and ProbeSetFreeze.Name = 'UMUTAffyExon_0209_RMA'
- -> and ProbeSet.Id = ProbeSetXRef.ProbeSetId
- -> order by ProbeSet.Id limit 5;
-+----------+---------+----------+------------------+---------+
-| id | Name | StrainID | Probesetfreezeid | value |
-+----------+---------+----------+------------------+---------+
-| 38574432 | 4331726 | 4 | 206 | 5.52895 |
-| 39254882 | 5054239 | 4 | 206 | 6.29465 |
-| 38867352 | 4642578 | 4 | 206 | 9.13706 |
-| 38637053 | 4398221 | 4 | 206 | 6.77672 |
-| 39715382 | 5543360 | 4 | 206 | 4.30016 |
-+----------+---------+----------+------------------+---------+
-5 rows in set (0.001 sec)
-#+END_SRC
-
-Now you can see the difference.
-
-#+BEGIN_SRC SQL
-select ProbeSetData.id,ProbeSet.name,strainid,probesetfreezeid,value from (ProbeSet,ProbeSetData,ProbeSetFreeze,ProbeSetXRef)
- where ProbeSetData.id=ProbeSetXRef.DataId
- and (strainid=4 or strainid=5)
- and ProbeSetXRef.ProbeSetFreezeId = 206
- and ProbeSet.Id = ProbeSetXRef.ProbeSetId
- and ProbeSet.name = '4331726'
- limit 5;
-
-+----------+---------+----------+------------------+---------+
-| id | name | strainid | probesetfreezeid | value |
-+----------+---------+----------+------------------+---------+
-| 38574432 | 4331726 | 4 | 206 | 5.52895 |
-+----------+---------+----------+------------------+---------+
-#+END_SRC
-
-It worked!
-
-BUT IT IS SLOW for the full query. This is now due to this table being huge
-and DataID distributed through the table (sigh!).
-
-#+BEGIN_SRC SQL
-MariaDB [db_webqtl]> select count(*) from ProbeSetXRef;
-+----------+
-| count(*) |
-+----------+
-| 47713039 |
-+----------+
-1 row in set (0.000 sec)
-#+END_SRC
-
-
-#+BEGIN_SRC SQL
-select ProbeSetData.id,ProbeSet.name,strainid,probesetfreezeid,value from (ProbeSet,ProbeSetData,ProbeSetFreeze,ProbeSetXRef)
- where
- ProbeSetXRef.ProbeSetFreezeId = 206
- and ProbeSet.Id = ProbeSetXRef.ProbeSetId
- and ProbeSetFreeze.Id = 206
- and ProbeSetData.id=ProbeSetXRef.DataId
- and (strainid=4 or strainid=5)
- limit 5;
-
-+----------+---------+----------+------------------+---------+
-| id | name | strainid | probesetfreezeid | value |
-+----------+---------+----------+------------------+---------+
-| 38549183 | 4304920 | 4 | 206 | 4.97269 |
-| 38549184 | 4304921 | 4 | 206 | 6.25133 |
-| 38549185 | 4304922 | 4 | 206 | 6.03701 |
-| 38549186 | 4304923 | 4 | 206 | 9.10316 |
-| 38549187 | 4304925 | 4 | 206 | 8.90826 |
-+----------+---------+----------+------------------+---------+
-5 rows in set (23.995 sec)
-
-select count(ProbeSetId) from ProbeSetXRef where ProbeSetFreezeId = 206;
-+-------------------+
-| count(ProbeSetId) |
-+-------------------+
-| 1236087 |
-+-------------------+
-
-select count(ProbeSet.name) from (ProbeSet,ProbeSetXRef)
- where ProbeSetFreezeId = 206
- and ProbeSet.Id = ProbeSetXRef.ProbeSetId;
-+----------------------+
-| count(ProbeSet.name) |
-+----------------------+
-| 1236087 |
-+----------------------+
-1 row in set (7.126 sec)
-
-select ProbeSet.name,ProbeSetData.id from (ProbeSet,ProbeSetXRef,ProbeSetData)
- where ProbeSetFreezeId = 206
- and ProbeSet.Id = ProbeSetXRef.ProbeSetId
- and ProbeSetData.id = ProbeSetXRef.DataId
-;
-
-MariaDB [db_webqtl]> select count(ProbeSetData.id) from (ProbeSet,ProbeSetXRef,ProbeSetData) where ProbeSetFreezeId = 206 and ProbeSet.Id = ProbeSetXRef.ProbeSetId and ProbeSetData.id = ProbeSetXRef.DataId;
-+------------------------+
-| count(ProbeSetData.id) |
-+------------------------+
-| 114956091 |
-+------------------------+
-1 row in set (35.836 sec)
-
-select count(*) from (ProbeSet,ProbeSetXRef,ProbeSetData) where ProbeSetFreezeId = 206 and ProbeSet.Id = ProbeSetXRef.ProbeSetId and ProbeSetData.id = ProbeSetXRef.DataId ;
-+-----------+
-| count(*) |
-+-----------+
-| 114956091 |
-+-----------+
-1 row in set (35.392 sec)
-
-
-select ProbeSet.name,ProbeSetData.value from (ProbeSet,ProbeSetXRef,ProbeSetData)
- where ProbeSetFreezeId = 206
- and ProbeSet.Id = ProbeSetXRef.ProbeSetId
- and ProbeSetData.id = ProbeSetXRef.DataId
-;
-
-select count(value) from (ProbeSet,ProbeSetXRef,ProbeSetData) where ProbeSetFreezeId = 206 and ProbeSet.Id = ProbeSetXRef.ProbeSetId and ProbeSetData.id = ProbeSetXRef.DataId and strainid=5 ;
-+--------------+
-| count(value) |
-+--------------+
-| 1236087 |
-+--------------+
-1 row in set (14.819 sec)
-
-
-select count(value) from (ProbeSet,ProbeSetXRef,ProbeSetData)
-where ProbeSetFreezeId = 206
- and ProbeSet.Id = ProbeSetXRef.ProbeSetId
- and ProbeSetData.id = ProbeSetXRef.DataId
- and ((strainid>=4 and strainid<=31) or strainid in (33,35,36,37,39,98,100,103))
-;
-
-+--------------+
-| count(value) |
-+--------------+
-| 43263045 |
-+--------------+
-1 row in set (1 min 40.498 sec)
-
-select name,strainid,value from (ProbeSet,ProbeSetXRef,ProbeSetData)
-where ProbeSetFreezeId = 206
- and ProbeSet.Id = ProbeSetXRef.ProbeSetId
- and ProbeSetData.id = ProbeSetXRef.DataId
- and ((strainid>=4 and strainid<=31) or strainid in (33,35,36,37,39,98,100,103))
-limit 5;
-+---------+----------+---------+
-| name | strainid | value |
-+---------+----------+---------+
-| 4331726 | 4 | 5.52895 |
-| 4331726 | 5 | 6.76158 |
-| 4331726 | 6 | 6.06911 |
-| 4331726 | 7 | 6.24858 |
-| 4331726 | 8 | 6.36076 |
-+---------+----------+---------+
-
-select name,strainid,value from (ProbeSet,ProbeSetXRef,ProbeSetData)
-where ProbeSetFreezeId = 206
- and ProbeSet.Id = ProbeSetXRef.ProbeSetId
- and ProbeSetData.id = ProbeSetXRef.DataId
- and ((strainid>=4 and strainid<=31) or strainid in (33,35,36,37,39,98,100,103))
-;
-
-#+END_SRC
-
-The final query works in 2.2 minutes on both Penguin2 and Tux01.
-
-** Original query
-
-This is the original query generated by GN2 that takes 1 hour on
-Penguin2 and 3 minutes on Tux01. Note it fetches all values for these 'traits' so essentially
-traverses the full 53GB database table (and even larger index) for each of
-them.
-
-#+BEGIN_SRC SQL
-SELECT ProbeSet.Name,T4.value, T5.value, T6.value, T7.value, T8.value, T9.value, T10.value, T11.value, T12.value, T13.value, T14.value, T15.value, T16.value, T17.value, T18.value, T19.value, T20.value, T21.value, T22.value, T23.value, T24.value, T25.value, T26.value, T28.value,
- T29.value, T30.value, T31.value, T33.value, T35.value, T36.value, T37.value, T39.value,
- T98.value, T100.value, T103.value FROM (ProbeSet, ProbeSetXRef, ProbeSetFreeze)
- left join ProbeSetData as T4 on T4.Id = ProbeSetXRef.DataId and T4.StrainId=4
- left join ProbeSetData as T5 on T5.Id = ProbeSetXRef.DataId and T5.StrainId=5
- left join ProbeSetData as T6 on T6.Id = ProbeSetXRef.DataId and T6.StrainId=6
- left join ProbeSetData as T7 on T7.Id = ProbeSetXRef.DataId and T7.StrainId=7
- left join ProbeSetData as T8 on T8.Id = ProbeSetXRef.DataId and T8.StrainId=8
- left join ProbeSetData as T9 on T9.Id = ProbeSetXRef.DataId and T9.StrainId=9
- left join ProbeSetData as T10 on T10.Id = ProbeSetXRef.DataId and T10.StrainId=10
- left join ProbeSetData as T11 on T11.Id = ProbeSetXRef.DataId and T11.StrainId=11
- left join ProbeSetData as T12 on T12.Id = ProbeSetXRef.DataId and T12.StrainId=12
- left join ProbeSetData as T13 on T13.Id = ProbeSetXRef.DataId and T13.StrainId=13
- left join ProbeSetData as T14 on T14.Id = ProbeSetXRef.DataId and T14.StrainId=14
- left join ProbeSetData as T15 on T15.Id = ProbeSetXRef.DataId and T15.StrainId=15
- left join ProbeSetData as T16 on T16.Id = ProbeSetXRef.DataId and T16.StrainId=16
- left join ProbeSetData as T17 on T17.Id = ProbeSetXRef.DataId and T17.StrainId=17
- left join ProbeSetData as T18 on T18.Id = ProbeSetXRef.DataId and T18.StrainId=18
- left join ProbeSetData as T19 on T19.Id = ProbeSetXRef.DataId and T19.StrainId=19
- left join ProbeSetData as T20 on T20.Id = ProbeSetXRef.DataId and T20.StrainId=20
- left join ProbeSetData as T21 on T21.Id = ProbeSetXRef.DataId and T21.StrainId=21
- left join ProbeSetData as T22 on T22.Id = ProbeSetXRef.DataId and T22.StrainId=22
- left join ProbeSetData as T23 on T23.Id = ProbeSetXRef.DataId and T23.StrainId=23
- left join ProbeSetData as T24 on T24.Id = ProbeSetXRef.DataId and T24.StrainId=24
- left join ProbeSetData as T25 on T25.Id = ProbeSetXRef.DataId and T25.StrainId=25
- left join ProbeSetData as T26 on T26.Id = ProbeSetXRef.DataId and T26.StrainId=26
- left join ProbeSetData as T28 on T28.Id = ProbeSetXRef.DataId and T28.StrainId=28
- left join ProbeSetData as T29 on T29.Id = ProbeSetXRef.DataId and T29.StrainId=29
- left join ProbeSetData as T30 on T30.Id = ProbeSetXRef.DataId and T30.StrainId=30
- left join ProbeSetData as T31 on T31.Id = ProbeSetXRef.DataId and T31.StrainId=31
- left join ProbeSetData as T33 on T33.Id = ProbeSetXRef.DataId and T33.StrainId=33
- left join ProbeSetData as T35 on T35.Id = ProbeSetXRef.DataId and T35.StrainId=35
- left join ProbeSetData as T36 on T36.Id = ProbeSetXRef.DataId and T36.StrainId=36
- left join ProbeSetData as T37 on T37.Id = ProbeSetXRef.DataId and T37.StrainId=37
- left join ProbeSetData as T39 on T39.Id = ProbeSetXRef.DataId and T39.StrainId=39
- left join ProbeSetData as T98 on T98.Id = ProbeSetXRef.DataId and T98.StrainId=98
- left join ProbeSetData as T100 on T100.Id = ProbeSetXRef.DataId and T100.StrainId=100
- left join ProbeSetData as T103 on T103.Id = ProbeSetXRef.DataId and T103.StrainId=103
- WHERE ProbeSetXRef.ProbeSetFreezeId = ProbeSetFreeze.Id
- and ProbeSetFreeze.Name = 'UMUTAffyExon_0209_RMA'
- and ProbeSet.Id = ProbeSetXRef.ProbeSetId
- order by ProbeSet.Id
-#+END_SRC