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<P class="title">HXB/BXH Genotype <A HREF="/webqtl/main.py?FormID=editHtml"><img src="/images/modify.gif" alt="modify this page" border= 0 valign="middle"></A></P>
<P class="subtitle"> Summary:</P>
<Blockquote>
The HXB/BXH Genotype Database was assembled by Robert W. Williams and Michal Pravenec using a compendium of approximately 1100 markers that have been typed over the past decade (please see Pravenec et al. <A HREF="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10730889&query_hl=2">1999</A> and Jirout et al.<A HREF="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12925886&query_hl=3">2003</A> for additional details of marker selection and genotyping). The final accepted genotype database contains 556 markers covering all 20 autosomes and the X chromosome. This file was updated November 2007 by RWW to correct some serious errors of maker order and to update the physical positions to the November 2004 assembly of the rat genome (still the most recent available to us).
<P>We hope to obtain much improved SNP-based rat chromosome maps in the next year (2008) from Dr. Hubner, Pravenec, and colleagues.
<P><A HREF="../genotypes/HXBBXH.geno" class="fs14"> Download</A> the entire HXB/BXH genotypes data set.
<P>Pravenec M, Kren V, Krenova D, Bila V, Zidek V, Simakova M, Musilova A, van Lith HA, van Zutphen LF (<A HREF="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10730889&query_hl=2">1999</A>) HXB/Ipcv and BXH/Cub recombinant inbred strains of the rat: strain distribution patterns of 632 alleles. Folia Biol (Praha) 45:203-215.
<P>Jirout M, Krenova D, Kren V, Breen L, Pravenec M, Schork NJ, Printz MP (<A HREF="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12925886&query_hl=3">2003</A>) A new framework marker-based linkage map and SDPs for the rat HXB/BXH strain set. Mammalian Genome 14:537-546.
<P>File updated by RWW, Nov 28, 2007.
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