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<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0 Transitional//EN">
<HTML><HEAD><TITLE>Publish Phenotype / WebQTL</TITLE>
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<P class="title">
BXH Published Phenotypes Database
<A HREF="/webqtl/main.py?FormID=editHtml"><img src="/images/modify.gif" alt="modify this page" border= 0 valign="middle"></A></P>
<P class="subtitle"> Summary:</P>
<Blockquote><P>
This BXH Phenotype Database includes published trait data for up to 20 recombinant inbred strains. Data were collected and curated at the University of Tennessee Health Science Center (UTHSC) starting in 2000.</P>
</Blockquote>
<P class="subtitle"> About the cases used in these studies:</P>
<Blockquote><P>
The BXH set were made by crossing female C57BL/6J (B6 or B) with male C3H/HeJ (C3) mice. Benjamin Taylor created the initial 12 BXH recombinant inbred strains at The Jackson Laboratory in 1969. A second set of eight BXH strains were initiated by Linda Siracusa at the Kimmel Cancer Center in 1995. She selected for tyrosinase-negative albinos and her strains should not be used to map on Chr 7. Four of these new BXH strains are now also available from The Jackson Laboratory. The following are the old and new symbols for the four recent additions:
<UL>
<LI>BXHA1/Sr = BXG20/Kcc
<LI>BXHA2/Sr = BXH21/Kcc
<LI>BXHB2/Sr = BXH22/Kcc
<LI>BXHE1/Sr = B6cC3-1/Kcc (backcrossed to B6 and a recombinant congenic)
</UL>
</Blockquote>
<P class="subtitle"> About data acquisition:</P>
<Blockquote><P>Published phenotypes were obtained through a literature search of PubMed-indexed journals. When possible, exact values of graphically represented data were obtained from the authors. In other cases graphs were measured using a vernier caliper. Some published and unpublished phenotypes were submitted directly by investigators. Unpublisehd phenotypes usually have Record ID numbers less than 1.</P>
<P>Each study has used mice purchased from The Jackson Laboratory or bred in-house. When available, PubMed links connect to abstracts and papers.</P>
<P>A BXH phenotypes Filemaker Pro database (current through to September 2004) can be searched online at <a href="http://www.nervenet.org/main/databases.html" target="_blank" class="fs14">http://www.nervenet.org/main/databases.html</a>.</P>
<P>How to obtain these strains: Please see <a href="http://jaxmice.jax.org/jaxmicedb/html/rcbinbred.shtml" target="_blank" class="fs14">http://jaxmice.jax.org/list/cat481378.html</a>.
</P>
</Blockquote>
<P class="subtitle"> Submitting data and reporting
mistakes:</P>
<Blockquote><P>The utility of this data set increases multiplicatively as each new phenotype is added. To submit data or report mistakes, please contact <a href="mailto:echesler@utmem.edu"><span style="font-weight: 400"> Elissa J. Chesler</span></a> and <a href="mailto:rwilliam@nb.utmem.edu"> <span style="font-weight: 400">Robert W. Williams</span></a> at the University of Tennessee Health Science Center.</P></Blockquote>
<P class="subtitle"> Acknowledgments:</P>
<Blockquote><P>The initial construction of this database was performed by Ryan McNeive, Nathan Copeland and Mary-Kathleen Sullivan at University of Tennessee Health Sciences Center.</P></Blockquote>
<P class="subtitle"> Information about this text file:</P>
<Blockquote><P>This text file originally generated by EJC, March 2004. Updated by RWW, October 30, 2004.
</P></Blockquote>
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