Many of the data types in the previous slide are hot-linked and it is easy to generate a small web of correlations between any transcript of interest and many other transcripts. In this case, we have used green lines between transcripts that have positive correlations, and red lines between transcripts that have negative correlations. Correlations have been multiplied by 100. The correlation of 0.96 between App and Hsp84-1 reads 96.  These are Pearson product moment correlations and they are sensitive to outliers. If you prefer, you can recompute Spearman rank order correlations.
	Where did Ndr4 (lower left) come from? It is not in the list in the previous slide. Actually it is. Nomenclature changes rapidly. If you click on R74996 in the previous slide (the active webqtl version) you will see that it now has a new symbol and name.
	What are all of the  conventions in this correlation network sketch.
	1.The official gene symbol = App
	2. OUr estimate of the location of these gene in the Mouse Genome Sequencing Consoritum version 3 build (MGSCv3). Chromosome followed by the megabase position relative to the centromere. (Mice only have one chromosome arm so this is an unambiguous coordinate. )
	3. The pair of numbers: top is the highest expression among the strain set. The lower number is the lowest expression of that transcript among the strain set.
	4. Vertical number on the right side of each box: this is the probe set ID given by Affymetrix. We have truncated these probe set IDs so you will not see the usual  ÒatÓ. A single gene may be represented by more than 10 probe sets. Thus this ID number is essential to identify the actual data source.
	5. Lower right corner: a two digit number followed by plus and minus signs. These numbers are the correlation value (absolute value) of the 100th best correlated transcript. The plus and minus signs indicate the mean polarity of the correlations.
	6. The set of numbers that read 2@140* etc. These are the approximate locations of additive effect QTLs detected by WebQTL that we will describe in other slides. Read this as: App has a suggestive QTL on Chr 2 at about 140 Mb and the D allele inherited from DBA/2J confirms a higher expression level at this marker.  If there is no star symbol, then it is not even formally ÒsuggestiveÓ but does make an interesting looking blip on the QTL radar screen.