<html> <head> <meta http-equiv=Content-Type content="text/html; charset=macintosh"> <meta name=ProgId content=PowerPoint.Slide> <meta name=Generator content="Microsoft Macintosh PowerPoint 10"> <link id=Main-File rel=Main-File href="WebQTLDemo.htm"> <title>PowerPoint Presentation - Complex trait analysis, develop-ment, and genomics</title> <link title="Presentation File" type="application/powerpoint" rel=alternate href=WebQTLDemo.ppt> <script> if ( ! top.PPTPRESENTATION ) { window.location.replace( "endshow.htm" ); } </script> <meta name=Description content="Jun-19-03: WebQTL Demonstration One please link to www.webqtl.org/search.html"> <link rel=Stylesheet href="master03_stylesheet.css"> <style media=print> <!--.sld {left:0px !important; width:6.0in !important; height:4.5in !important; font-size:76% !important;} --> </style> <script language=JavaScript src=script.js></script><script language=JavaScript><!-- gId="slide0001.htm" if ( !parent.base.g_done && (parent.base.msie < 0 ) ) { parent.base.g_done = 1; document.location.replace( parent.base.GetHrefObj(parent.base.g_currentSlide).m_slideHref); } if( !IsNts() ) Redirect( "PPTSld", gId ); var g_hasTrans = true, g_autoTrans = false, g_transSecs = 1; //--> </script><script for=window event=onload language=JavaScript><!-- if( !IsSldOrNts() ) return; if( MakeNotesVis() ) return; LoadSld( gId ); playList();MakeSldVis(1); //--> </script> </head> <body style='margin:0px;background-color:black' onclick="DocumentOnClick(event)" onresize="_RSW()" onkeypress="_KPH(event)"> <div id=SlideObj class=sld style='position:absolute;top:0px;left:0px; width:755px;height:566px;font-size:16px;background-color:#484848;clip:rect(0%, 101%, 101%, 0%); visibility:hidden'><img src="master03_background.gif" v:shapes="_x0000_s1026" style='position:absolute;top:0%;left:0%;width:100.0%;height:100.0%'> <div style='position:absolute;top:6.89%;left:3.31%;width:96.42%;height:19.61%; filter:DropShadow(Color=#000000, OffX=2, OffY=2)'> <div class=T style='mso-line-spacing:" 0 ";mso-margin-left-alt:232; mso-text-indent-alt:0;position:absolute;top:0%;left:1.09%;width:97.39%; height:100.0%'><span style='position:absolute;top:0%;left:0%;width:100.0%'><span style='font-size:68%'><i>WebQTL Demonstration One<br> </i></span></span><span style='position:absolute;top:33.33%;left:4.23%;width:95.76%'><span style='font-size:68%'><i>please link to <br> </i></span></span><span style='position:absolute;top:58.55%;left:4.23%;width:95.76%'><span style='font-size:86%'><i>www.webqtl.org/search.html</i></span><span style='font-size:68%;mso-special-format:lastCR;display:none'><i><br> </i></span></span></div> </div> <div style='position:absolute;top:31.62%;left:5.43%;width:73.24%;height:45.05%; filter:DropShadow(Color=#000000, OffX=1, OffY=1)'> <div class=B style='position:absolute;top:0%;left:2.71%;width:97.28%; height:93.33%'> <div style='mso-line-spacing:" 0 ";mso-margin-left-alt:348;mso-text-indent-alt: 56;position:absolute;top:0%;left:0%;width:89.77%;height:39.91%'><span style='position:absolute;top:0%;left:0%;width:100.0%'><span style='mso-special-format: nobullet;display:none;color:#FBFDB8;font-family:"Monotype Sorts";font-size: 99%'>l</span><span style='font-size:94%;color:#E9EB5D;mso-color-index:3'>Part 1: How to discover shared </span></span><span style='position:absolute; top:30.52%;left:7.86%;width:86.54%'><span style='font-size:94%;color:#E9EB5D; mso-color-index:3'>expression patterns (slides </span></span><span style='position:absolute;top:61.05%;left:7.86%;width:86.54%'><span style='font-size:94%;color:#E9EB5D;mso-color-index:3'>2�14)<br> </span></span></div> <div style='mso-line-spacing:" 0 ";mso-margin-left-alt:348;mso-text-indent-alt: 56;position:absolute;top:48.31%;left:0%;width:84.94%;height:27.73%'><span style='position:absolute;top:0%;left:0%;width:100.0%'><span style='mso-special-format: nobullet;display:none;color:#FBFDB8;font-family:"Monotype Sorts";font-size: 99%'>l</span><span style='font-size:94%;color:#E9EB5D;mso-color-index:3'>Part 2. Discovering upstream </span></span><span style='position:absolute; top:43.93%;left:8.31%;width:91.46%'><span style='font-size:94%;color:#E9EB5D; mso-color-index:3'>modulators (15�25)<br> </span></span></div> <div style='mso-line-spacing:" 0 ";mso-margin-left-alt:348;mso-text-indent-alt: 56;position:absolute;top:84.45%;left:0%;width:100.0%;height:15.54%'><span style='position:absolute;top:0%;left:7.06%;width:92.93%'><span style='font-size:94%;color:#E9EB5D;mso-color-index:3'><span style='mso-special-format: "numbullet3\,3";color:#FBFDB8;position:absolute;left:-7.6%;font-family:Times; font-size:99%'>3.</span></span><span style='font-size:94%;color:#E9EB5D; mso-color-index:3'>Discovering downstream targets</span></span></div> </div> </div> <img border=0 src="slide0001_image001.gif" style='position:absolute;top:21.9%; left:74.56%;width:23.57%;height:64.31%'> <div class=O style='position:absolute;top:79.32%;left:75.89%;width:10.46%; height:14.48%'> <div style='mso-line-spacing:" 0 0";mso-margin-left-alt:17;mso-text-indent-alt: 17;position:absolute;top:0%;left:0%;width:100.0%;height:42.68%'><span style='font-family:"Arial Rounded MT Bold";font-size:233%;color:#6E6E6E'>RNA</span><span style='font-family:"Arial Rounded MT Bold";font-size:300%;color:#6E6E6E; display:none'><br> </span></div> <div style='mso-line-spacing:" 0 0";mso-margin-left-alt:17;mso-text-indent-alt: 17;position:absolute;top:46.34%;left:0%;width:82.27%;height:54.87%'><span style='font-family:"Arial Rounded MT Bold";font-size:300%;color:#6E6E6E; mso-special-format:lastCR;display:none'><br> </span></div> </div> <div class=O style='position:absolute;top:76.5%;left:4.37%;width:78.67%; height:13.07%'><span style='position:absolute;top:0%;left:0%;width:98.98%'><span style='font-family:"Gill Sans";font-size:250%;color:#E9EB5D;mso-color-index: 3'><i>PowerPoint �Normal view� has notes that </i></span></span><span style='position:absolute;top:51.35%;left:0%;width:100.0%'><span style='font-family:"Gill Sans";font-size:250%;color:#E9EB5D;mso-color-index: 3'><i>may be useful companions to these slides.</i></span><span style='font-family:"Gill Sans";font-size:250%;color:#E9EB5D;mso-color-index: 3;mso-special-format:lastCR;display:none'><br> </span></span></div> </div> <div id=NotesObj style='display:none'> <table style='color:white' border=0 width="100%"> <tr> <td width=5 nowrap></td> <td width="100%"></td> </tr> <tr> <td colspan=1></td> <td align=left colspan=1><font face=Helvetica size=3>Welcome to a short demonstation of WebQTL. Please adjust the wize of windows on your monitor so that you can see part of this page as well as WebQTL windows. WebQTL will produce a potentially large number of new windows (pop-ups), so you may need to modify your browser preferences to permit pop-ups.<span style="mso-spacerun: yes"> </span>In this demonstration, we explore one important transcript expressed in the brain: the amyloid beta precursor protein messenger RNA. The product of this mRNA, the APP protein, is associated with Alzheimer disease.</font><br> </td> </tr> <tr> <td colspan=1></td> <td align=left colspan=1><br> </td> </tr> <tr> <td colspan=1></td> <td align=left colspan=1><font face=Helvetica size=3>(Initial version of June 2003 by Rob Williams, Last edits June 16, 2003 by RW.)</font><br> </td> </tr> </table> </div> <script language=JavaScript><!-- function playList() { } //--> </script> </body> </html>