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-rw-r--r--wqflask/wqflask/my_pylmm/pyLMM/gn2.py26
-rw-r--r--wqflask/wqflask/my_pylmm/pyLMM/kinship.py49
-rw-r--r--wqflask/wqflask/my_pylmm/pyLMM/lmm.py2
-rw-r--r--wqflask/wqflask/my_pylmm/pyLMM/runlmm.py3
-rw-r--r--wqflask/wqflask/my_pylmm/pyLMM/standalone.py14
5 files changed, 50 insertions, 44 deletions
diff --git a/wqflask/wqflask/my_pylmm/pyLMM/gn2.py b/wqflask/wqflask/my_pylmm/pyLMM/gn2.py
index 4702c670..c71b9f22 100644
--- a/wqflask/wqflask/my_pylmm/pyLMM/gn2.py
+++ b/wqflask/wqflask/my_pylmm/pyLMM/gn2.py
@@ -37,11 +37,17 @@ def callbacks():
progress = progress,
mprint = mprint
)
-
+
+def uses(*funcs):
+ """
+ Some sugar
+ """
+ return [callbacks()[func] for func in funcs]
+
# ----- Minor test cases:
if __name__ == '__main__':
- logging.basicConfig(level=logging.DEBUG)
+ # logging.basicConfig(level=logging.DEBUG)
logging.debug("Test %i" % (1))
d = callbacks()['debug']
d("TEST")
@@ -49,3 +55,19 @@ if __name__ == '__main__':
wrln("Hello %i" % 34)
progress = callbacks()['progress']
progress("I am half way",50,100)
+ list = [0.5,0.6096595 , -0.31559815, -0.52793285, 1.16573418e-15,
+ 0.5,0.6096595 , -0.31559815, -0.52793285, 1.16573418e-15,
+ 0.5,0.6096595 , -0.31559815, -0.52793285, 1.16573418e-15,
+ 0.5,0.6096595 , -0.31559815, -0.52793285, 1.16573418e-15,
+ 0.5,0.6096595 , -0.31559815, -0.52793285, 1.16573418e-15]
+ mprint("list",list)
+ matrix = [[1,0.5,0.6096595 , -0.31559815, -0.52793285, 1.16573418e-15],
+ [2,0.5,0.6096595 , -0.31559815, -0.52793285, 1.16573418e-15],
+ [3,0.5,0.6096595 , -0.31559815, -0.52793285, 1.16573418e-15],
+ [4,0.5,0.6096595 , -0.31559815, -0.52793285, 1.16573418e-15],
+ [5,0.5,0.6096595 , -0.31559815, -0.52793285, 1.16573418e-15],
+ [6,0.5,0.6096595 , -0.31559815, -0.52793285, 1.16573418e-15]]
+ mprint("matrix",matrix)
+ ix,dx = uses("info","debug")
+ ix("ix")
+ dx("dx")
diff --git a/wqflask/wqflask/my_pylmm/pyLMM/kinship.py b/wqflask/wqflask/my_pylmm/pyLMM/kinship.py
index d3792570..62f7be47 100644
--- a/wqflask/wqflask/my_pylmm/pyLMM/kinship.py
+++ b/wqflask/wqflask/my_pylmm/pyLMM/kinship.py
@@ -74,46 +74,39 @@ def f_init(q):
# Calculate the kinship matrix from G (SNPs as rows!), returns K
#
-def kinship(G,computeSize=1000,numThreads=None,useBLAS=False,verbose=True):
- numThreads = None
- if numThreads:
- numThreads = int(numThreads)
+def kinship(G,uses,computeSize=1000,numThreads=None,useBLAS=False):
+ progress,debug,info,mprint = uses('progress','debug','info','mprint')
+
matrix_initialize(useBLAS)
-
- sys.stderr.write(str(G.shape)+"\n")
+
+ mprint("G",G)
n = G.shape[1] # inds
inds = n
m = G.shape[0] # snps
snps = m
- sys.stderr.write(str(m)+" SNPs\n")
+ info("%i SNPs" % (m))
assert snps>inds, "snps should be larger than inds (%i snps, %i inds)" % (snps,inds)
q = mp.Queue()
p = mp.Pool(numThreads, f_init, [q])
cpu_num = mp.cpu_count()
- print "CPU cores:",cpu_num
- print snps,computeSize
+ info("CPU cores: %i" % cpu_num)
iterations = snps/computeSize+1
- # if testing:
- # iterations = 8
- # jobs = range(0,8) # range(0,iterations)
results = []
-
K = np.zeros((n,n)) # The Kinship matrix has dimension individuals x individuals
completed = 0
for job in range(iterations):
- if verbose:
- sys.stderr.write("Processing job %d first %d SNPs\n" % (job, ((job+1)*computeSize)))
+ info("Processing job %d first %d SNPs" % (job, ((job+1)*computeSize)))
W = compute_W(job,G,n,snps,computeSize)
if numThreads == 1:
# Single-core
compute_matrixMult(job,W,q)
j,x = q.get()
- if verbose: sys.stderr.write("Job "+str(j)+" finished\n")
+ debug("Job "+str(j)+" finished")
+ progress("kinship",j,iterations)
K_j = x
- # print j,K_j[:,0]
K = K + K_j
else:
# Multi-core
@@ -123,39 +116,27 @@ def kinship(G,computeSize=1000,numThreads=None,useBLAS=False,verbose=True):
time.sleep(0.1)
try:
j,x = q.get_nowait()
- if verbose: sys.stderr.write("Job "+str(j)+" finished\n")
+ debug("Job "+str(j)+" finished")
K_j = x
- # print j,K_j[:,0]
K = K + K_j
completed += 1
+ progress("kinship",completed,iterations)
except Queue.Empty:
pass
if numThreads == None or numThreads > 1:
- # results contains the growing result set
for job in range(len(results)-completed):
j,x = q.get(True,15)
- if verbose: sys.stderr.write("Job "+str(j)+" finished\n")
+ debug("Job "+str(j)+" finished")
K_j = x
- # print j,K_j[:,0]
K = K + K_j
completed += 1
+ progress("kinship",completed,iterations)
K = K / float(snps)
-
- # outFile = 'runtest.kin'
- # if verbose: sys.stderr.write("Saving Kinship file to %s\n" % outFile)
- # np.savetxt(outFile,K)
-
- # if saveKvaKve:
- # if verbose: sys.stderr.write("Obtaining Eigendecomposition\n")
- # Kva,Kve = linalg.eigh(K)
- # if verbose: sys.stderr.write("Saving eigendecomposition to %s.[kva | kve]\n" % outFile)
- # np.savetxt(outFile+".kva",Kva)
- # np.savetxt(outFile+".kve",Kve)
return K
-def kvakve(K, uses):
+def kvakve(K,uses):
"""
Obtain eigendecomposition for K and return Kva,Kve where Kva is cleaned
of small values < 1e-6 (notably smaller than zero)
diff --git a/wqflask/wqflask/my_pylmm/pyLMM/lmm.py b/wqflask/wqflask/my_pylmm/pyLMM/lmm.py
index 2076bc84..5182e73c 100644
--- a/wqflask/wqflask/my_pylmm/pyLMM/lmm.py
+++ b/wqflask/wqflask/my_pylmm/pyLMM/lmm.py
@@ -395,7 +395,7 @@ def calculate_kinship_new(genotype_matrix, temp_data=None):
print("call genotype.normalize")
G = np.apply_along_axis( genotype.normalize, axis=0, arr=genotype_matrix)
print("call calculate_kinship_new")
- return kinship(G.T),G # G gets transposed, we'll turn this into an iterator (FIXME)
+ return kinship(G.T,uses),G # G gets transposed, we'll turn this into an iterator (FIXME)
def calculate_kinship_old(genotype_matrix, temp_data=None):
"""
diff --git a/wqflask/wqflask/my_pylmm/pyLMM/runlmm.py b/wqflask/wqflask/my_pylmm/pyLMM/runlmm.py
index 324c4f2c..e3e8659c 100644
--- a/wqflask/wqflask/my_pylmm/pyLMM/runlmm.py
+++ b/wqflask/wqflask/my_pylmm/pyLMM/runlmm.py
@@ -25,6 +25,7 @@ from lmm import gn2_load_redis, calculate_kinship_old
from kinship import kinship, kinship_full
import genotype
import phenotype
+from standalone import uses
usage = """
python runlmm.py [options] command
@@ -193,7 +194,7 @@ elif cmd == 'kinship':
k2 = round(K2[0][0],4)
print "Genotype",G.shape, "\n", G
- K3 = kinship(G.T)
+ K3 = kinship(G.T,uses)
print "third Kinship method",K3.shape,"\n",K3
sys.stderr.write(options.geno+"\n")
k3 = round(K3[0][0],4)
diff --git a/wqflask/wqflask/my_pylmm/pyLMM/standalone.py b/wqflask/wqflask/my_pylmm/pyLMM/standalone.py
index 705da21f..538007f1 100644
--- a/wqflask/wqflask/my_pylmm/pyLMM/standalone.py
+++ b/wqflask/wqflask/my_pylmm/pyLMM/standalone.py
@@ -12,11 +12,13 @@ import numpy as np
import sys
import logging
+# logger = logging.getLogger(__name__)
+logger = logging.getLogger('lmm2')
logging.basicConfig(level=logging.DEBUG)
np.set_printoptions(precision=3,suppress=True)
def progress(location, count, total):
- logging.info("Progress: %s %d%%" % (location,round(count*100.0/total)))
+ logger.info("Progress: %s %d%%" % (location,round(count*100.0/total)))
def mprint(msg,data):
"""
@@ -36,11 +38,11 @@ def callbacks():
return dict(
write = sys.stdout.write,
writeln = print,
- debug = logging.debug,
- info = logging.info,
- warning = logging.warning,
- error = logging.error,
- critical = logging.critical,
+ debug = logger.debug,
+ info = logger.info,
+ warning = logger.warning,
+ error = logger.error,
+ critical = logger.critical,
progress = progress,
mprint = mprint
)