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-rw-r--r--wqflask/wqflask/my_pylmm/pyLMM/runlmm.py35
1 files changed, 19 insertions, 16 deletions
diff --git a/wqflask/wqflask/my_pylmm/pyLMM/runlmm.py b/wqflask/wqflask/my_pylmm/pyLMM/runlmm.py
index 1af5a443..708c9185 100644
--- a/wqflask/wqflask/my_pylmm/pyLMM/runlmm.py
+++ b/wqflask/wqflask/my_pylmm/pyLMM/runlmm.py
@@ -54,9 +54,9 @@ parser.add_option("--geno",dest="geno",
parser.add_option("--maf-normalization",
action="store_true", dest="maf_normalization", default=False,
help="Apply MAF genotype normalization")
-parser.add_option("--skip-genotype-normalization",
- action="store_true", dest="skip_genotype_normalization", default=False,
- help="Skip genotype normalization")
+parser.add_option("--genotype-normalization",
+ action="store_true", dest="genotype_normalization", default=False,
+ help="Force genotype normalization")
parser.add_option("-q", "--quiet",
action="store_false", dest="verbose", default=True,
help="don't print status messages to stdout")
@@ -100,7 +100,8 @@ if options.geno:
print g.shape
if cmd == 'redis_new':
- # Emulating the redis setup of GN2
+ # The main difference between redis_new and redis is that missing
+ # phenotypes are handled by the first
Y = y
G = g
print "Original G",G.shape, "\n", G
@@ -109,7 +110,7 @@ if cmd == 'redis_new':
G = None
ps, ts = gn2_load_redis('testrun','other',k,Y,gt,new_code=True)
print np.array(ps)
- print sum(ps)
+ print len(ps),sum(ps)
# Test results
p1 = round(ps[0],4)
p2 = round(ps[-1],4)
@@ -118,12 +119,14 @@ if cmd == 'redis_new':
assert p1==0.0708, "p1=%f" % p1
assert p2==0.1417, "p2=%f" % p2
if options.geno == 'data/small_na.geno':
- assert p1==0.0958, "p1=%f" % p1
- assert p2==0.0435, "p2=%f" % p2
+ assert p1==0.0897, "p1=%f" % p1
+ assert p2==0.0405, "p2=%f" % p2
if options.geno == 'data/test8000.geno':
assert p1==0.8984, "p1=%f" % p1
- assert p2==0.9623, "p2=%f" % p2
-if cmd == 'redis':
+ assert p2==0.9620, "p2=%f" % p2
+ assert sum(ps) == 4070.02346579
+ assert len(ps) == 8000
+elif cmd == 'redis':
# Emulating the redis setup of GN2
G = g
print "Original G",G.shape, "\n", G
@@ -135,7 +138,7 @@ if cmd == 'redis':
if options.maf_normalization:
G = np.apply_along_axis( genotype.replace_missing_with_MAF, axis=0, arr=g )
print "MAF replacements: \n",G
- if not options.skip_genotype_normalization:
+ if options.genotype_normalization:
G = np.apply_along_axis( genotype.normalize, axis=1, arr=G)
g = None
gnt = None
@@ -144,8 +147,8 @@ if cmd == 'redis':
G = None
ps, ts = gn2_load_redis('testrun','other',k,Y,gt, new_code=False)
print np.array(ps)
- print sum(ps)
- # Test results
+ print len(ps),sum(ps)
+ # Test results 4070.02346579
p1 = round(ps[0],4)
p2 = round(ps[-1],4)
sys.stderr.write(options.geno+"\n")
@@ -153,11 +156,11 @@ if cmd == 'redis':
assert p1==0.0708, "p1=%f" % p1
assert p2==0.1417, "p2=%f" % p2
if options.geno == 'data/small_na.geno':
- assert p1==0.0958, "p1=%f" % p1
- assert p2==0.0435, "p2=%f" % p2
+ assert p1==0.0897, "p1=%f" % p1
+ assert p2==0.0405, "p2=%f" % p2
if options.geno == 'data/test8000.geno':
assert p1==0.8984, "p1=%f" % p1
- assert p2==0.9623, "p2=%f" % p2
+ assert p2==0.8827, "p2=%f" % p2
elif cmd == 'kinship':
G = g
print "Original G",G.shape, "\n", G
@@ -169,7 +172,7 @@ elif cmd == 'kinship':
if options.maf_normalization:
G = np.apply_along_axis( genotype.replace_missing_with_MAF, axis=0, arr=g )
print "MAF replacements: \n",G
- if not options.skip_genotype_normalization:
+ if options.genotype_normalization:
G = np.apply_along_axis( genotype.normalize, axis=1, arr=G)
g = None
gnt = None