diff options
Diffstat (limited to 'wqflask/base')
| -rw-r--r-- | wqflask/base/GeneralObject.py | 4 | ||||
| -rw-r--r-- | wqflask/base/data_set.py | 136 | ||||
| -rw-r--r-- | wqflask/base/mrna_assay_tissue_data.py | 24 | ||||
| -rw-r--r-- | wqflask/base/species.py | 89 | ||||
| -rw-r--r-- | wqflask/base/trait.py | 84 | ||||
| -rw-r--r-- | wqflask/base/webqtlCaseData.py | 9 | ||||
| -rw-r--r-- | wqflask/base/webqtlConfig.py | 42 |
7 files changed, 166 insertions, 222 deletions
diff --git a/wqflask/base/GeneralObject.py b/wqflask/base/GeneralObject.py index 249195e2..ce8e60b8 100644 --- a/wqflask/base/GeneralObject.py +++ b/wqflask/base/GeneralObject.py @@ -62,5 +62,5 @@ class GeneralObject: return s def __eq__(self, other): - return (len(list(self.__dict__.keys())) == - len(list(other.__dict__.keys()))) + return (len(list(self.__dict__.keys())) + == len(list(other.__dict__.keys()))) diff --git a/wqflask/base/data_set.py b/wqflask/base/data_set.py index d0f5e6f2..75ddf278 100644 --- a/wqflask/base/data_set.py +++ b/wqflask/base/data_set.py @@ -17,7 +17,10 @@ # at rwilliams@uthsc.edu and xzhou15@uthsc.edu # # This module is used by GeneNetwork project (www.genenetwork.org) - +from dataclasses import dataclass +from dataclasses import field +from dataclasses import InitVar +from typing import Optional, Dict from db.call import fetchall, fetchone, fetch1 from utility.logger import getLogger from utility.tools import USE_GN_SERVER, USE_REDIS, flat_files, flat_file_exists, GN2_BASE_URL @@ -59,7 +62,8 @@ logger = getLogger(__name__) DS_NAME_MAP = {} -def create_dataset(dataset_name, dataset_type=None, get_samplelist=True, group_name=None): +def create_dataset(dataset_name, dataset_type=None, + get_samplelist=True, group_name=None): if dataset_name == "Temp": dataset_type = "Temp" @@ -74,11 +78,10 @@ def create_dataset(dataset_name, dataset_type=None, get_samplelist=True, group_n return dataset_class(dataset_name, get_samplelist) +@dataclass class DatasetType: - - def __init__(self, redis_instance): - """Create a dictionary of samples where the value is set to Geno, -Publish or ProbeSet. E.g. + """Create a dictionary of samples where the value is set to Geno, + Publish or ProbeSet. E.g. {'AD-cases-controls-MyersGeno': 'Geno', 'AD-cases-controls-MyersPublish': 'Publish', @@ -89,21 +92,28 @@ Publish or ProbeSet. E.g. 'All Phenotypes': 'Publish', 'B139_K_1206_M': 'ProbeSet', 'B139_K_1206_R': 'ProbeSet' ... - + } """ + redis_instance: InitVar[Redis] + datasets: Optional[Dict] = field(init=False, default_factory=dict) + data: Optional[Dict] = field(init=False) + + def __post_init__(self, redis_instance): self.redis_instance = redis_instance - self.datasets = {} - data = self.redis_instance.get("dataset_structure") + data = redis_instance.get("dataset_structure") if data: self.datasets = json.loads(data) - else: # ZS: I don't think this should ever run unless Redis is emptied + else: + # ZS: I don't think this should ever run unless Redis is + # emptied try: data = json.loads(requests.get( - GN2_BASE_URL + "/api/v_pre1/gen_dropdown", timeout=5).content) - for species in data['datasets']: - for group in data['datasets'][species]: - for dataset_type in data['datasets'][species][group]: - for dataset in data['datasets'][species][group][dataset_type]: + GN2_BASE_URL + "/api/v_pre1/gen_dropdown", + timeout=5).content) + for _species in data['datasets']: + for group in data['datasets'][_species]: + for dataset_type in data['datasets'][_species][group]: + for dataset in data['datasets'][_species][group][dataset_type]: short_dataset_name = dataset[1] if dataset_type == "Phenotypes": new_type = "Publish" @@ -112,16 +122,16 @@ Publish or ProbeSet. E.g. else: new_type = "ProbeSet" self.datasets[short_dataset_name] = new_type - except: + except Exception: # Do nothing pass - self.redis_instance.set( - "dataset_structure", json.dumps(self.datasets)) + self.redis_instance.set("dataset_structure", + json.dumps(self.datasets)) + self.data = data def set_dataset_key(self, t, name): - """If name is not in the object's dataset dictionary, set it, and update - dataset_structure in Redis - + """If name is not in the object's dataset dictionary, set it, and + update dataset_structure in Redis args: t: Type of dataset structure which can be: 'mrna_expr', 'pheno', 'other_pheno', 'geno' @@ -129,19 +139,20 @@ Publish or ProbeSet. E.g. """ sql_query_mapping = { - 'mrna_expr': ("""SELECT ProbeSetFreeze.Id FROM """ + - """ProbeSetFreeze WHERE ProbeSetFreeze.Name = "{}" """), - 'pheno': ("""SELECT InfoFiles.GN_AccesionId """ + - """FROM InfoFiles, PublishFreeze, InbredSet """ + - """WHERE InbredSet.Name = '{}' AND """ + - """PublishFreeze.InbredSetId = InbredSet.Id AND """ + - """InfoFiles.InfoPageName = PublishFreeze.Name"""), - 'other_pheno': ("""SELECT PublishFreeze.Name """ + - """FROM PublishFreeze, InbredSet """ + - """WHERE InbredSet.Name = '{}' AND """ + - """PublishFreeze.InbredSetId = InbredSet.Id"""), - 'geno': ("""SELECT GenoFreeze.Id FROM GenoFreeze WHERE """ + - """GenoFreeze.Name = "{}" """) + 'mrna_expr': ("SELECT ProbeSetFreeze.Id FROM " + "ProbeSetFreeze WHERE " + "ProbeSetFreeze.Name = \"%s\" "), + 'pheno': ("SELECT InfoFiles.GN_AccesionId " + "FROM InfoFiles, PublishFreeze, InbredSet " + "WHERE InbredSet.Name = '%s' AND " + "PublishFreeze.InbredSetId = InbredSet.Id AND " + "InfoFiles.InfoPageName = PublishFreeze.Name"), + 'other_pheno': ("SELECT PublishFreeze.Name " + "FROM PublishFreeze, InbredSet " + "WHERE InbredSet.Name = '%s' AND " + "PublishFreeze.InbredSetId = InbredSet.Id"), + 'geno': ("SELECT GenoFreeze.Id FROM GenoFreeze WHERE " + "GenoFreeze.Name = \"%s\" ") } dataset_name_mapping = { @@ -155,21 +166,20 @@ Publish or ProbeSet. E.g. if t in ['pheno', 'other_pheno']: group_name = name.replace("Publish", "") - results = g.db.execute( - sql_query_mapping[t].format(group_name)).fetchone() + + results = g.db.execute(sql_query_mapping[t] % group_name).fetchone() if results: self.datasets[name] = dataset_name_mapping[t] self.redis_instance.set( "dataset_structure", json.dumps(self.datasets)) return True - return None def __call__(self, name): - if name not in self.datasets: for t in ["mrna_expr", "pheno", "other_pheno", "geno"]: - # This has side-effects, with the end result being a truth-y value + # This has side-effects, with the end result being a + # truth-y value if(self.set_dataset_key(t, name)): break # Return None if name has not been set @@ -208,12 +218,12 @@ def create_datasets_list(): if USE_REDIS: r.set(key, pickle.dumps(datasets, pickle.HIGHEST_PROTOCOL)) - r.expire(key, 60*60) + r.expire(key, 60 * 60) return datasets -class Markers(object): +class Markers: """Todo: Build in cacheing so it saves us reading the same file more than once""" def __init__(self, name): @@ -232,7 +242,8 @@ class Markers(object): for line in bimbam_fh: marker = {} marker['name'] = line.split(delimiter)[0].rstrip() - marker['Mb'] = float(line.split(delimiter)[1].rstrip())/1000000 + marker['Mb'] = float(line.split(delimiter)[ + 1].rstrip()) / 1000000 marker['chr'] = line.split(delimiter)[2].rstrip() markers.append(marker) @@ -266,8 +277,6 @@ class Markers(object): elif isinstance(p_values, dict): filtered_markers = [] for marker in self.markers: - #logger.debug("marker[name]", marker['name']) - #logger.debug("p_values:", p_values) if marker['name'] in p_values: #logger.debug("marker {} IS in p_values".format(i)) marker['p_value'] = p_values[marker['name']] @@ -280,10 +289,6 @@ class Markers(object): marker['lrs_value'] = - \ math.log10(marker['p_value']) * 4.61 filtered_markers.append(marker) - # else: - #logger.debug("marker {} NOT in p_values".format(i)) - # self.markers.remove(marker) - #del self.markers[i] self.markers = filtered_markers @@ -310,13 +315,11 @@ class HumanMarkers(Markers): marker['Mb'] = float(splat[3]) / 1000000 self.markers.append(marker) - #logger.debug("markers is: ", pf(self.markers)) - def add_pvalues(self, p_values): super(HumanMarkers, self).add_pvalues(p_values) -class DatasetGroup(object): +class DatasetGroup: """ Each group has multiple datasets; each species has multiple groups. @@ -369,8 +372,8 @@ class DatasetGroup(object): def get_markers(self): def check_plink_gemma(): if flat_file_exists("mapping"): - MAPPING_PATH = flat_files("mapping")+"/" - if os.path.isfile(MAPPING_PATH+self.name+".bed"): + MAPPING_PATH = flat_files("mapping") + "/" + if os.path.isfile(MAPPING_PATH + self.name + ".bed"): return True return False @@ -416,7 +419,7 @@ class DatasetGroup(object): else: logger.debug("Cache not hit") - genotype_fn = locate_ignore_error(self.name+".geno", 'genotype') + genotype_fn = locate_ignore_error(self.name + ".geno", 'genotype') if genotype_fn: self.samplelist = get_group_samplelists.get_samplelist( "geno", genotype_fn) @@ -425,7 +428,7 @@ class DatasetGroup(object): if USE_REDIS: r.set(key, json.dumps(self.samplelist)) - r.expire(key, 60*5) + r.expire(key, 60 * 5) def all_samples_ordered(self): result = [] @@ -524,7 +527,6 @@ def datasets(group_name, this_group=None): break if tissue_already_exists: - #logger.debug("dataset_menu:", dataset_menu[i]['datasets']) dataset_menu[i]['datasets'].append((dataset, dataset_short)) else: dataset_menu.append(dict(tissue=tissue_name, @@ -532,7 +534,7 @@ def datasets(group_name, this_group=None): if USE_REDIS: r.set(key, pickle.dumps(dataset_menu, pickle.HIGHEST_PROTOCOL)) - r.expire(key, 60*5) + r.expire(key, 60 * 5) if this_group != None: this_group._datasets = dataset_menu @@ -541,7 +543,7 @@ def datasets(group_name, this_group=None): return dataset_menu -class DataSet(object): +class DataSet: """ DataSet class defines a dataset in webqtl, can be either Microarray, Published phenotype, genotype, or user input dataset(temp) @@ -573,15 +575,6 @@ class DataSet(object): self.group.get_samplelist() self.species = species.TheSpecies(self) - def get_desc(self): - """Gets overridden later, at least for Temp...used by trait's get_given_name""" - return None - - # Delete this eventually - @property - def riset(): - Weve_Renamed_This_As_Group - def get_accession_id(self): if self.type == "Publish": results = g.db.execute("""select InfoFiles.GN_AccesionId from InfoFiles, PublishFreeze, InbredSet where @@ -632,7 +625,7 @@ class DataSet(object): WHERE ProbeSetFreeze.ProbeFreezeId = ProbeFreeze.Id AND ProbeFreeze.TissueId = Tissue.Id AND (ProbeSetFreeze.Name = '%s' OR ProbeSetFreeze.FullName = '%s' OR ProbeSetFreeze.ShortName = '%s') - """ % (query_args), "/dataset/"+self.name+".json", + """ % (query_args), "/dataset/" + self.name + ".json", lambda r: (r["id"], r["name"], r["full_name"], r["short_name"], r["data_scale"], r["tissue"]) ) @@ -741,9 +734,6 @@ class PhenotypeDataSet(DataSet): DS_NAME_MAP['Publish'] = 'PhenotypeDataSet' def setup(self): - - #logger.debug("IS A PHENOTYPEDATASET") - # Fields in the database table self.search_fields = ['Phenotype.Post_publication_description', 'Phenotype.Pre_publication_description', @@ -1046,8 +1036,8 @@ class MrnaAssayDataSet(DataSet): else: description_display = this_trait.symbol - if (len(description_display) > 1 and description_display != 'N/A' and - len(target_string) > 1 and target_string != 'None'): + if (len(description_display) > 1 and description_display != 'N/A' + and len(target_string) > 1 and target_string != 'None'): description_display = description_display + '; ' + target_string.strip() # Save it for the jinja2 template diff --git a/wqflask/base/mrna_assay_tissue_data.py b/wqflask/base/mrna_assay_tissue_data.py index 5a64afb2..8f8e2b0a 100644 --- a/wqflask/base/mrna_assay_tissue_data.py +++ b/wqflask/base/mrna_assay_tissue_data.py @@ -10,9 +10,10 @@ from gn3.db_utils import database_connector from utility.logger import getLogger -logger = getLogger(__name__ ) +logger = getLogger(__name__) -class MrnaAssayTissueData(object): + +class MrnaAssayTissueData: def __init__(self, gene_symbols=None): self.gene_symbols = gene_symbols @@ -21,7 +22,7 @@ class MrnaAssayTissueData(object): self.data = collections.defaultdict(Bunch) - query = '''select t.Symbol, t.GeneId, t.DataId, t.Chr, t.Mb, t.description, t.Probe_Target_Description + query = '''select t.Symbol, t.GeneId, t.DataId, t.Chr, t.Mb, t.description, t.Probe_Target_Description from ( select Symbol, max(Mean) as maxmean from TissueProbeSetXRef @@ -32,14 +33,14 @@ class MrnaAssayTissueData(object): # Due to the limit size of TissueProbeSetFreezeId table in DB, # performance of inner join is acceptable.MrnaAssayTissueData(gene_symbols=symbol_list) if len(gene_symbols) == 0: - query += '''Symbol!='' and Symbol Is Not Null group by Symbol) + query += '''Symbol!='' and Symbol Is Not Null group by Symbol) as x inner join TissueProbeSetXRef as t on t.Symbol = x.Symbol and t.Mean = x.maxmean; ''' else: in_clause = db_tools.create_in_clause(gene_symbols) - #ZS: This was in the query, not sure why: http://docs.python.org/2/library/string.html?highlight=lower#string.lower + # ZS: This was in the query, not sure why: http://docs.python.org/2/library/string.html?highlight=lower#string.lower query += ''' Symbol in {} group by Symbol) as x inner join TissueProbeSetXRef as t on t.Symbol = x.Symbol and t.Mean = x.maxmean; @@ -67,16 +68,16 @@ class MrnaAssayTissueData(object): self.data[symbol].probe_target_description = result.Probe_Target_Description ########################################################################### - #Input: cursor, symbolList (list), dataIdDict(Dict) - #output: symbolValuepairDict (dictionary):one dictionary of Symbol and Value Pair, + # Input: cursor, symbolList (list), dataIdDict(Dict) + # output: symbolValuepairDict (dictionary):one dictionary of Symbol and Value Pair, # key is symbol, value is one list of expression values of one probeSet; - #function: get one dictionary whose key is gene symbol and value is tissue expression data (list type). - #Attention! All keys are lower case! + # function: get one dictionary whose key is gene symbol and value is tissue expression data (list type). + # Attention! All keys are lower case! ########################################################################### def get_symbol_values_pairs(self): id_list = [self.data[symbol].data_id for symbol in self.data] - + symbol_values_dict = {} if len(id_list) > 0: @@ -91,6 +92,7 @@ class MrnaAssayTissueData(object): if result.Symbol.lower() not in symbol_values_dict: symbol_values_dict[result.Symbol.lower()] = [result.value] else: - symbol_values_dict[result.Symbol.lower()].append(result.value) + symbol_values_dict[result.Symbol.lower()].append( + result.value) return symbol_values_dict diff --git a/wqflask/base/species.py b/wqflask/base/species.py index 2771d116..f303aabb 100644 --- a/wqflask/base/species.py +++ b/wqflask/base/species.py @@ -1,55 +1,66 @@ -import collections +from collections import OrderedDict +from dataclasses import dataclass +from dataclasses import InitVar +from typing import Optional, Dict +from flask import g -from flask import Flask, g +@dataclass +class TheSpecies: + """Data related to species.""" + dataset: Optional[Dict] = None + species_name: Optional[str] = None -from utility.logger import getLogger -logger = getLogger(__name__ ) - -class TheSpecies(object): - def __init__(self, dataset=None, species_name=None): - if species_name != None: - self.name = species_name + def __post_init__(self): + if self.species_name is not None: + self.name = self.species_name self.chromosomes = Chromosomes(species=self.name) else: - self.dataset = dataset self.chromosomes = Chromosomes(dataset=self.dataset) -class IndChromosome(object): - def __init__(self, name, length): - self.name = name - self.length = length + +@dataclass +class IndChromosome: + """Data related to IndChromosome""" + name: str + length: int @property def mb_length(self): - """Chromosome length in megabases""" + """Chromosome length in mega-bases""" return self.length / 1000000 -class Chromosomes(object): - def __init__(self, dataset=None, species=None): - self.chromosomes = collections.OrderedDict() - if species != None: - query = """ - Select - Chr_Length.Name, Chr_Length.OrderId, Length from Chr_Length, Species - where - Chr_Length.SpeciesId = Species.SpeciesId AND - Species.Name = '%s' - Order by OrderId - """ % species.capitalize() - else: + +@dataclass +class Chromosomes: + """Data related to a chromosome""" + dataset: InitVar[Dict] = None + species: Optional[str] = None + + def __post_init__(self, dataset): + if self.species is None: self.dataset = dataset - query = """ - Select - Chr_Length.Name, Chr_Length.OrderId, Length from Chr_Length, InbredSet - where - Chr_Length.SpeciesId = InbredSet.SpeciesId AND - InbredSet.Name = '%s' - Order by OrderId - """ % self.dataset.group.name - logger.sql(query) + @property + def chromosomes(self): + """Lazily fetch the chromosomes""" + chromosomes = OrderedDict() + if self.species is not None: + query = ( + "SELECT Chr_Length.Name, Chr_Length.OrderId, Length " + "FROM Chr_Length, Species WHERE " + "Chr_Length.SpeciesId = Species.SpeciesId AND " + "Species.Name = " + "'%s' ORDER BY OrderId" % self.species.capitalize()) + else: + query = ( + "SELECT Chr_Length.Name, Chr_Length.OrderId, " + "Length FROM Chr_Length, InbredSet WHERE " + "Chr_Length.SpeciesId = InbredSet.SpeciesId AND " + "InbredSet.Name = " + "'%s' ORDER BY OrderId" % self.dataset.group.name) results = g.db.execute(query).fetchall() - for item in results: - self.chromosomes[item.OrderId] = IndChromosome(item.Name, item.Length) + chromosomes[item.OrderId] = IndChromosome( + item.Name, item.Length) + return chromosomes diff --git a/wqflask/base/trait.py b/wqflask/base/trait.py index df96d46e..d09cfd40 100644 --- a/wqflask/base/trait.py +++ b/wqflask/base/trait.py @@ -51,7 +51,7 @@ def create_trait(**kw): return None -class GeneralTrait(object): +class GeneralTrait: """ Trait class defines a trait in webqtl, can be either Microarray, Published phenotype, genotype, or user input trait @@ -337,74 +337,10 @@ def jsonable(trait): dataset_name=dataset.shortname, location=trait.location_repr ) - else: - return dict() - - -def jsonable_table_row(trait, dataset_name, index): - """Return a list suitable for json and intended to be displayed in a table - - Actual turning into json doesn't happen here though""" - - dataset = create_dataset(dataset_name) - - if dataset.type == "ProbeSet": - if trait.mean == "": - mean = "N/A" - else: - mean = "%.3f" % round(float(trait.mean), 2) - if trait.additive == "": - additive = "N/A" - else: - additive = "%.3f" % round(float(trait.additive), 2) - return ['<input type="checkbox" name="searchResult" class="checkbox trait_checkbox" value="' + hmac.data_hmac('{}:{}'.format(str(trait.name), dataset.name)) + '">', - index, - '<a href="/show_trait?trait_id=' + - str(trait.name)+'&dataset='+dataset.name + - '">'+str(trait.name)+'</a>', - trait.symbol, - trait.description_display, - trait.location_repr, - mean, - trait.LRS_score_repr, - trait.LRS_location_repr, - additive] - elif dataset.type == "Publish": - if trait.additive == "": - additive = "N/A" - else: - additive = "%.2f" % round(float(trait.additive), 2) - if trait.pubmed_id: - return ['<input type="checkbox" name="searchResult" class="checkbox trait_checkbox" value="' + hmac.data_hmac('{}:{}'.format(str(trait.name), dataset.name)) + '">', - index, - '<a href="/show_trait?trait_id=' + - str(trait.name)+'&dataset='+dataset.name + - '">'+str(trait.name)+'</a>', - trait.description_display, - trait.authors, - '<a href="' + trait.pubmed_link + '">' + trait.pubmed_text + '</href>', - trait.LRS_score_repr, - trait.LRS_location_repr, - additive] - else: - return ['<input type="checkbox" name="searchResult" class="checkbox trait_checkbox" value="' + hmac.data_hmac('{}:{}'.format(str(trait.name), dataset.name)) + '">', - index, - '<a href="/show_trait?trait_id=' + - str(trait.name)+'&dataset='+dataset.name + - '">'+str(trait.name)+'</a>', - trait.description_display, - trait.authors, - trait.pubmed_text, - trait.LRS_score_repr, - trait.LRS_location_repr, - additive] - elif dataset.type == "Geno": - return ['<input type="checkbox" name="searchResult" class="checkbox trait_checkbox" value="' + hmac.data_hmac('{}:{}'.format(str(trait.name), dataset.name)) + '">', - index, - '<a href="/show_trait?trait_id=' + - str(trait.name)+'&dataset='+dataset.name + - '">'+str(trait.name)+'</a>', - trait.location_repr] + elif dataset.name == "Temp": + return dict(name=trait.name, + dataset="Temp", + dataset_name="Temp") else: return dict() @@ -543,9 +479,9 @@ def retrieve_trait_info(trait, dataset, get_qtl_info=False): else: description_display = trait.symbol - if (str(description_display or "") != "" and - description_display != 'N/A' and - str(target_string or "") != "" and target_string != 'None'): + if (str(description_display or "") != "" + and description_display != 'N/A' + and str(target_string or "") != "" and target_string != 'None'): description_display = description_display + '; ' + target_string.strip() # Save it for the jinja2 template @@ -639,6 +575,6 @@ def retrieve_trait_info(trait, dataset, get_qtl_info=False): if str(trait.lrs or "") != "": trait.LRS_score_repr = LRS_score_repr = '%3.1f' % trait.lrs else: - raise KeyError(repr(trait.name) + - ' information is not found in the database.') + raise KeyError(repr(trait.name) + + ' information is not found in the database.') return trait diff --git a/wqflask/base/webqtlCaseData.py b/wqflask/base/webqtlCaseData.py index aa55470f..25b6cb8a 100644 --- a/wqflask/base/webqtlCaseData.py +++ b/wqflask/base/webqtlCaseData.py @@ -28,17 +28,20 @@ import utility.tools utility.tools.show_settings() + class webqtlCaseData: """one case data in one trait""" def __init__(self, name, value=None, variance=None, num_cases=None, name2=None): self.name = name - self.name2 = name2 # Other name (for traits like BXD65a) + # Other name (for traits like BXD65a) + self.name2 = name2 self.value = value # Trait Value self.variance = variance # Trait Variance self.num_cases = num_cases # Number of individuals/cases self.extra_attributes = None - self.this_id = None # Set a sane default (can't be just "id" cause that's a reserved word) + # Set a sane default (can't be just "id" cause that's a reserved word) + self.this_id = None self.outlier = None # Not set to True/False until later def __repr__(self): @@ -78,4 +81,4 @@ class webqtlCaseData: def display_num_cases(self): if self.num_cases is not None: return "%s" % self.num_cases - return "x"
\ No newline at end of file + return "x" diff --git a/wqflask/base/webqtlConfig.py b/wqflask/base/webqtlConfig.py index aee8616a..39947158 100644 --- a/wqflask/base/webqtlConfig.py +++ b/wqflask/base/webqtlConfig.py @@ -1,4 +1,4 @@ -#########################################' +# ' # Environment Variables - public # # Note: much of this needs to handled by the settings/environment @@ -10,35 +10,35 @@ from utility.tools import valid_path, mk_dir, assert_dir, assert_writable_dir, flat_files, TEMPDIR -#Debug Level -#1 for debug, mod python will reload import each time +# Debug Level +# 1 for debug, mod python will reload import each time DEBUG = 1 -#USER privilege -USERDICT = {'guest':1,'user':2, 'admin':3, 'root':4} +# USER privilege +USERDICT = {'guest': 1, 'user': 2, 'admin': 3, 'root': 4} -#Set privileges +# Set privileges SUPER_PRIVILEGES = {'data': 'edit', 'metadata': 'edit', 'admin': 'edit-admins'} DEFAULT_PRIVILEGES = {'data': 'view', 'metadata': 'view', 'admin': 'not-admin'} -#minimum number of informative strains +# minimum number of informative strains KMININFORMATIVE = 5 -#Daily download limit from one IP +# Daily download limit from one IP DAILYMAXIMUM = 1000 -#maximum LRS value +# maximum LRS value MAXLRS = 460.0 -#MINIMUM Database public value +# MINIMUM Database public value PUBLICTHRESH = 0 -#EXTERNAL LINK ADDRESSES +# EXTERNAL LINK ADDRESSES PUBMEDLINK_URL = "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=%s&dopt=Abstract" UCSC_BLAT = 'http://genome.ucsc.edu/cgi-bin/hgBlat?org=%s&db=%s&type=0&sort=0&output=0&userSeq=%s' UTHSC_BLAT = 'http://ucscbrowser.genenetwork.org/cgi-bin/hgBlat?org=%s&db=%s&type=0&sort=0&output=0&userSeq=%s' UTHSC_BLAT2 = 'http://ucscbrowserbeta.genenetwork.org/cgi-bin/hgBlat?org=%s&db=%s&type=0&sort=0&output=0&userSeq=%s' -GENOMEBROWSER_URL="https://genome.ucsc.edu/cgi-bin/hgTracks?db=%s&position=%s" +GENOMEBROWSER_URL = "https://genome.ucsc.edu/cgi-bin/hgTracks?db=%s&position=%s" NCBI_LOCUSID = "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=%s" GENBANK_ID = "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=Nucleotide&cmd=search&doptcmdl=DocSum&term=%s" OMIM_ID = "http://www.ncbi.nlm.nih.gov/omim/%s" @@ -56,26 +56,28 @@ GEMMA_URL = "http://www.chibi.ubc.ca/Gemma/gene/showGene.html?ncbiid=%s" ABA_URL = "http://mouse.brain-map.org/search/show?search_type=gene&search_term=%s" EBIGWAS_URL = "https://www.ebi.ac.uk/gwas/search?query=%s" WIKI_PI_URL = "http://severus.dbmi.pitt.edu/wiki-pi/index.php/search?q=%s" -ENSEMBLETRANSCRIPT_URL="http://useast.ensembl.org/Mus_musculus/Transcript/Idhistory?t=%s" +ENSEMBLETRANSCRIPT_URL = "http://useast.ensembl.org/Mus_musculus/Transcript/Idhistory?t=%s" DBSNP = 'http://ensembl.org/Mus_musculus/Variation/Population?v=%s' PROTEIN_ATLAS_URL = "http://www.proteinatlas.org/search/%s" OPEN_TARGETS_URL = "https://genetics.opentargets.org/gene/%s" UNIPROT_URL = "https://www.uniprot.org/uniprot/%s" RGD_URL = "https://rgd.mcw.edu/rgdweb/elasticResults.html?term=%s&category=Gene&species=%s" PHENOGEN_URL = "https://phenogen.org/gene.jsp?speciesCB=Rn&auto=Y&geneTxt=%s&genomeVer=rn6§ion=geneEQTL" +RRID_MOUSE_URL = "https://www.jax.org/strain/%s" +RRID_RAT_URL = "https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=%s" # Temporary storage (note that this TMPDIR can be set as an # environment variable - use utility.tools.TEMPDIR when you # want to reach this base dir assert_writable_dir(TEMPDIR) -TMPDIR = mk_dir(TEMPDIR+'/gn2/') +TMPDIR = mk_dir(TEMPDIR + '/gn2/') assert_writable_dir(TMPDIR) -CACHEDIR = mk_dir(TMPDIR+'/cache/') +CACHEDIR = mk_dir(TMPDIR + '/cache/') # We can no longer write into the git tree: -GENERATED_IMAGE_DIR = mk_dir(TMPDIR+'generated/') -GENERATED_TEXT_DIR = mk_dir(TMPDIR+'generated_text/') +GENERATED_IMAGE_DIR = mk_dir(TMPDIR + 'generated/') +GENERATED_TEXT_DIR = mk_dir(TMPDIR + 'generated_text/') # Make sure we have permissions to access these assert_writable_dir(CACHEDIR) @@ -83,12 +85,12 @@ assert_writable_dir(GENERATED_IMAGE_DIR) assert_writable_dir(GENERATED_TEXT_DIR) # Flat file directories -GENODIR = flat_files('genotype')+'/' +GENODIR = flat_files('genotype') + '/' assert_dir(GENODIR) # assert_dir(GENODIR+'bimbam') # for gemma # JSON genotypes are OBSOLETE -JSON_GENODIR = flat_files('genotype/json')+'/' +JSON_GENODIR = flat_files('genotype/json') + '/' if not valid_path(JSON_GENODIR): # fall back on old location (move the dir, FIXME) JSON_GENODIR = flat_files('json') @@ -96,4 +98,4 @@ if not valid_path(JSON_GENODIR): # Are we using the following...? PORTADDR = "http://50.16.251.170" INFOPAGEHREF = '/dbdoc/%s.html' -CGIDIR = '/webqtl/' #XZ: The variable name 'CGIDIR' should be changed to 'PYTHONDIR' +CGIDIR = '/webqtl/' # XZ: The variable name 'CGIDIR' should be changed to 'PYTHONDIR' |