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-rw-r--r--wqflask/base/GeneralObject.py4
-rw-r--r--wqflask/base/data_set.py29
-rw-r--r--wqflask/base/mrna_assay_tissue_data.py22
-rw-r--r--wqflask/base/species.py8
-rw-r--r--wqflask/base/trait.py10
-rw-r--r--wqflask/base/webqtlCaseData.py9
-rw-r--r--wqflask/base/webqtlConfig.py40
7 files changed, 66 insertions, 56 deletions
diff --git a/wqflask/base/GeneralObject.py b/wqflask/base/GeneralObject.py
index 249195e2..ce8e60b8 100644
--- a/wqflask/base/GeneralObject.py
+++ b/wqflask/base/GeneralObject.py
@@ -62,5 +62,5 @@ class GeneralObject:
return s
def __eq__(self, other):
- return (len(list(self.__dict__.keys())) ==
- len(list(other.__dict__.keys())))
+ return (len(list(self.__dict__.keys()))
+ == len(list(other.__dict__.keys())))
diff --git a/wqflask/base/data_set.py b/wqflask/base/data_set.py
index 3183363b..e20f2f98 100644
--- a/wqflask/base/data_set.py
+++ b/wqflask/base/data_set.py
@@ -150,8 +150,8 @@ class DatasetType:
"FROM PublishFreeze, InbredSet "
"WHERE InbredSet.Name = '%s' AND "
"PublishFreeze.InbredSetId = InbredSet.Id"),
- 'geno': ("SELECT GenoFreeze.Id FROM GenoFreeze WHERE "
- "GenoFreeze.Name = \"%s\" ")
+ 'geno': ("SELECT GenoFreeze.Id FROM GenoFreeze WHERE "
+ "GenoFreeze.Name = \"%s\" ")
}
dataset_name_mapping = {
@@ -168,7 +168,8 @@ class DatasetType:
results = g.db.execute(sql_query_mapping[t] % group_name).fetchone()
if results:
self.datasets[name] = dataset_name_mapping[t]
- self.redis_instance.set("dataset_structure", json.dumps(self.datasets))
+ self.redis_instance.set(
+ "dataset_structure", json.dumps(self.datasets))
return True
return None
@@ -215,7 +216,7 @@ def create_datasets_list():
if USE_REDIS:
r.set(key, pickle.dumps(datasets, pickle.HIGHEST_PROTOCOL))
- r.expire(key, 60*60)
+ r.expire(key, 60 * 60)
return datasets
@@ -239,7 +240,8 @@ class Markers:
for line in bimbam_fh:
marker = {}
marker['name'] = line.split(delimiter)[0].rstrip()
- marker['Mb'] = float(line.split(delimiter)[1].rstrip())/1000000
+ marker['Mb'] = float(line.split(delimiter)[
+ 1].rstrip()) / 1000000
marker['chr'] = line.split(delimiter)[2].rstrip()
markers.append(marker)
@@ -311,7 +313,6 @@ class HumanMarkers(Markers):
marker['Mb'] = float(splat[3]) / 1000000
self.markers.append(marker)
-
def add_pvalues(self, p_values):
super(HumanMarkers, self).add_pvalues(p_values)
@@ -369,8 +370,8 @@ class DatasetGroup:
def get_markers(self):
def check_plink_gemma():
if flat_file_exists("mapping"):
- MAPPING_PATH = flat_files("mapping")+"/"
- if os.path.isfile(MAPPING_PATH+self.name+".bed"):
+ MAPPING_PATH = flat_files("mapping") + "/"
+ if os.path.isfile(MAPPING_PATH + self.name + ".bed"):
return True
return False
@@ -416,7 +417,7 @@ class DatasetGroup:
else:
logger.debug("Cache not hit")
- genotype_fn = locate_ignore_error(self.name+".geno", 'genotype')
+ genotype_fn = locate_ignore_error(self.name + ".geno", 'genotype')
if genotype_fn:
self.samplelist = get_group_samplelists.get_samplelist(
"geno", genotype_fn)
@@ -425,7 +426,7 @@ class DatasetGroup:
if USE_REDIS:
r.set(key, json.dumps(self.samplelist))
- r.expire(key, 60*5)
+ r.expire(key, 60 * 5)
def all_samples_ordered(self):
result = []
@@ -531,7 +532,7 @@ def datasets(group_name, this_group=None):
if USE_REDIS:
r.set(key, pickle.dumps(dataset_menu, pickle.HIGHEST_PROTOCOL))
- r.expire(key, 60*5)
+ r.expire(key, 60 * 5)
if this_group != None:
this_group._datasets = dataset_menu
@@ -622,7 +623,7 @@ class DataSet:
WHERE ProbeSetFreeze.ProbeFreezeId = ProbeFreeze.Id
AND ProbeFreeze.TissueId = Tissue.Id
AND (ProbeSetFreeze.Name = '%s' OR ProbeSetFreeze.FullName = '%s' OR ProbeSetFreeze.ShortName = '%s')
- """ % (query_args), "/dataset/"+self.name+".json",
+ """ % (query_args), "/dataset/" + self.name + ".json",
lambda r: (r["id"], r["name"], r["full_name"],
r["short_name"], r["data_scale"], r["tissue"])
)
@@ -1031,8 +1032,8 @@ class MrnaAssayDataSet(DataSet):
else:
description_display = this_trait.symbol
- if (len(description_display) > 1 and description_display != 'N/A' and
- len(target_string) > 1 and target_string != 'None'):
+ if (len(description_display) > 1 and description_display != 'N/A'
+ and len(target_string) > 1 and target_string != 'None'):
description_display = description_display + '; ' + target_string.strip()
# Save it for the jinja2 template
diff --git a/wqflask/base/mrna_assay_tissue_data.py b/wqflask/base/mrna_assay_tissue_data.py
index 1f8224af..882ae911 100644
--- a/wqflask/base/mrna_assay_tissue_data.py
+++ b/wqflask/base/mrna_assay_tissue_data.py
@@ -9,7 +9,8 @@ from utility.db_tools import escape
from utility.logger import getLogger
-logger = getLogger(__name__ )
+logger = getLogger(__name__)
+
class MrnaAssayTissueData:
@@ -20,7 +21,7 @@ class MrnaAssayTissueData:
self.data = collections.defaultdict(Bunch)
- query = '''select t.Symbol, t.GeneId, t.DataId, t.Chr, t.Mb, t.description, t.Probe_Target_Description
+ query = '''select t.Symbol, t.GeneId, t.DataId, t.Chr, t.Mb, t.description, t.Probe_Target_Description
from (
select Symbol, max(Mean) as maxmean
from TissueProbeSetXRef
@@ -31,14 +32,14 @@ class MrnaAssayTissueData:
# Due to the limit size of TissueProbeSetFreezeId table in DB,
# performance of inner join is acceptable.MrnaAssayTissueData(gene_symbols=symbol_list)
if len(gene_symbols) == 0:
- query += '''Symbol!='' and Symbol Is Not Null group by Symbol)
+ query += '''Symbol!='' and Symbol Is Not Null group by Symbol)
as x inner join TissueProbeSetXRef as t on t.Symbol = x.Symbol
and t.Mean = x.maxmean;
'''
else:
in_clause = db_tools.create_in_clause(gene_symbols)
- #ZS: This was in the query, not sure why: http://docs.python.org/2/library/string.html?highlight=lower#string.lower
+ # ZS: This was in the query, not sure why: http://docs.python.org/2/library/string.html?highlight=lower#string.lower
query += ''' Symbol in {} group by Symbol)
as x inner join TissueProbeSetXRef as t on t.Symbol = x.Symbol
and t.Mean = x.maxmean;
@@ -64,16 +65,16 @@ class MrnaAssayTissueData:
self.data[symbol].probe_target_description = result.Probe_Target_Description
###########################################################################
- #Input: cursor, symbolList (list), dataIdDict(Dict)
- #output: symbolValuepairDict (dictionary):one dictionary of Symbol and Value Pair,
+ # Input: cursor, symbolList (list), dataIdDict(Dict)
+ # output: symbolValuepairDict (dictionary):one dictionary of Symbol and Value Pair,
# key is symbol, value is one list of expression values of one probeSet;
- #function: get one dictionary whose key is gene symbol and value is tissue expression data (list type).
- #Attention! All keys are lower case!
+ # function: get one dictionary whose key is gene symbol and value is tissue expression data (list type).
+ # Attention! All keys are lower case!
###########################################################################
def get_symbol_values_pairs(self):
id_list = [self.data[symbol].data_id for symbol in self.data]
-
+
symbol_values_dict = {}
if len(id_list) > 0:
@@ -87,6 +88,7 @@ class MrnaAssayTissueData:
if result.Symbol.lower() not in symbol_values_dict:
symbol_values_dict[result.Symbol.lower()] = [result.value]
else:
- symbol_values_dict[result.Symbol.lower()].append(result.value)
+ symbol_values_dict[result.Symbol.lower()].append(
+ result.value)
return symbol_values_dict
diff --git a/wqflask/base/species.py b/wqflask/base/species.py
index eae3325a..e3c29916 100644
--- a/wqflask/base/species.py
+++ b/wqflask/base/species.py
@@ -4,7 +4,8 @@ from flask import Flask, g
from utility.logger import getLogger
-logger = getLogger(__name__ )
+logger = getLogger(__name__)
+
class TheSpecies:
def __init__(self, dataset=None, species_name=None):
@@ -15,6 +16,7 @@ class TheSpecies:
self.dataset = dataset
self.chromosomes = Chromosomes(dataset=self.dataset)
+
class IndChromosome:
def __init__(self, name, length):
self.name = name
@@ -25,6 +27,7 @@ class IndChromosome:
"""Chromosome length in megabases"""
return self.length / 1000000
+
class Chromosomes:
def __init__(self, dataset=None, species=None):
self.chromosomes = collections.OrderedDict()
@@ -52,4 +55,5 @@ class Chromosomes:
results = g.db.execute(query).fetchall()
for item in results:
- self.chromosomes[item.OrderId] = IndChromosome(item.Name, item.Length)
+ self.chromosomes[item.OrderId] = IndChromosome(
+ item.Name, item.Length)
diff --git a/wqflask/base/trait.py b/wqflask/base/trait.py
index 5574128d..d09cfd40 100644
--- a/wqflask/base/trait.py
+++ b/wqflask/base/trait.py
@@ -479,9 +479,9 @@ def retrieve_trait_info(trait, dataset, get_qtl_info=False):
else:
description_display = trait.symbol
- if (str(description_display or "") != "" and
- description_display != 'N/A' and
- str(target_string or "") != "" and target_string != 'None'):
+ if (str(description_display or "") != ""
+ and description_display != 'N/A'
+ and str(target_string or "") != "" and target_string != 'None'):
description_display = description_display + '; ' + target_string.strip()
# Save it for the jinja2 template
@@ -575,6 +575,6 @@ def retrieve_trait_info(trait, dataset, get_qtl_info=False):
if str(trait.lrs or "") != "":
trait.LRS_score_repr = LRS_score_repr = '%3.1f' % trait.lrs
else:
- raise KeyError(repr(trait.name) +
- ' information is not found in the database.')
+ raise KeyError(repr(trait.name)
+ + ' information is not found in the database.')
return trait
diff --git a/wqflask/base/webqtlCaseData.py b/wqflask/base/webqtlCaseData.py
index aa55470f..25b6cb8a 100644
--- a/wqflask/base/webqtlCaseData.py
+++ b/wqflask/base/webqtlCaseData.py
@@ -28,17 +28,20 @@ import utility.tools
utility.tools.show_settings()
+
class webqtlCaseData:
"""one case data in one trait"""
def __init__(self, name, value=None, variance=None, num_cases=None, name2=None):
self.name = name
- self.name2 = name2 # Other name (for traits like BXD65a)
+ # Other name (for traits like BXD65a)
+ self.name2 = name2
self.value = value # Trait Value
self.variance = variance # Trait Variance
self.num_cases = num_cases # Number of individuals/cases
self.extra_attributes = None
- self.this_id = None # Set a sane default (can't be just "id" cause that's a reserved word)
+ # Set a sane default (can't be just "id" cause that's a reserved word)
+ self.this_id = None
self.outlier = None # Not set to True/False until later
def __repr__(self):
@@ -78,4 +81,4 @@ class webqtlCaseData:
def display_num_cases(self):
if self.num_cases is not None:
return "%s" % self.num_cases
- return "x" \ No newline at end of file
+ return "x"
diff --git a/wqflask/base/webqtlConfig.py b/wqflask/base/webqtlConfig.py
index bb8704a5..39947158 100644
--- a/wqflask/base/webqtlConfig.py
+++ b/wqflask/base/webqtlConfig.py
@@ -1,4 +1,4 @@
-#########################################'
+# '
# Environment Variables - public
#
# Note: much of this needs to handled by the settings/environment
@@ -10,35 +10,35 @@
from utility.tools import valid_path, mk_dir, assert_dir, assert_writable_dir, flat_files, TEMPDIR
-#Debug Level
-#1 for debug, mod python will reload import each time
+# Debug Level
+# 1 for debug, mod python will reload import each time
DEBUG = 1
-#USER privilege
-USERDICT = {'guest':1,'user':2, 'admin':3, 'root':4}
+# USER privilege
+USERDICT = {'guest': 1, 'user': 2, 'admin': 3, 'root': 4}
-#Set privileges
+# Set privileges
SUPER_PRIVILEGES = {'data': 'edit', 'metadata': 'edit', 'admin': 'edit-admins'}
DEFAULT_PRIVILEGES = {'data': 'view', 'metadata': 'view', 'admin': 'not-admin'}
-#minimum number of informative strains
+# minimum number of informative strains
KMININFORMATIVE = 5
-#Daily download limit from one IP
+# Daily download limit from one IP
DAILYMAXIMUM = 1000
-#maximum LRS value
+# maximum LRS value
MAXLRS = 460.0
-#MINIMUM Database public value
+# MINIMUM Database public value
PUBLICTHRESH = 0
-#EXTERNAL LINK ADDRESSES
+# EXTERNAL LINK ADDRESSES
PUBMEDLINK_URL = "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=%s&dopt=Abstract"
UCSC_BLAT = 'http://genome.ucsc.edu/cgi-bin/hgBlat?org=%s&db=%s&type=0&sort=0&output=0&userSeq=%s'
UTHSC_BLAT = 'http://ucscbrowser.genenetwork.org/cgi-bin/hgBlat?org=%s&db=%s&type=0&sort=0&output=0&userSeq=%s'
UTHSC_BLAT2 = 'http://ucscbrowserbeta.genenetwork.org/cgi-bin/hgBlat?org=%s&db=%s&type=0&sort=0&output=0&userSeq=%s'
-GENOMEBROWSER_URL="https://genome.ucsc.edu/cgi-bin/hgTracks?db=%s&position=%s"
+GENOMEBROWSER_URL = "https://genome.ucsc.edu/cgi-bin/hgTracks?db=%s&position=%s"
NCBI_LOCUSID = "http://www.ncbi.nlm.nih.gov/gene?cmd=Retrieve&dopt=Graphics&list_uids=%s"
GENBANK_ID = "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=Nucleotide&cmd=search&doptcmdl=DocSum&term=%s"
OMIM_ID = "http://www.ncbi.nlm.nih.gov/omim/%s"
@@ -56,7 +56,7 @@ GEMMA_URL = "http://www.chibi.ubc.ca/Gemma/gene/showGene.html?ncbiid=%s"
ABA_URL = "http://mouse.brain-map.org/search/show?search_type=gene&search_term=%s"
EBIGWAS_URL = "https://www.ebi.ac.uk/gwas/search?query=%s"
WIKI_PI_URL = "http://severus.dbmi.pitt.edu/wiki-pi/index.php/search?q=%s"
-ENSEMBLETRANSCRIPT_URL="http://useast.ensembl.org/Mus_musculus/Transcript/Idhistory?t=%s"
+ENSEMBLETRANSCRIPT_URL = "http://useast.ensembl.org/Mus_musculus/Transcript/Idhistory?t=%s"
DBSNP = 'http://ensembl.org/Mus_musculus/Variation/Population?v=%s'
PROTEIN_ATLAS_URL = "http://www.proteinatlas.org/search/%s"
OPEN_TARGETS_URL = "https://genetics.opentargets.org/gene/%s"
@@ -71,13 +71,13 @@ RRID_RAT_URL = "https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=%s"
# want to reach this base dir
assert_writable_dir(TEMPDIR)
-TMPDIR = mk_dir(TEMPDIR+'/gn2/')
+TMPDIR = mk_dir(TEMPDIR + '/gn2/')
assert_writable_dir(TMPDIR)
-CACHEDIR = mk_dir(TMPDIR+'/cache/')
+CACHEDIR = mk_dir(TMPDIR + '/cache/')
# We can no longer write into the git tree:
-GENERATED_IMAGE_DIR = mk_dir(TMPDIR+'generated/')
-GENERATED_TEXT_DIR = mk_dir(TMPDIR+'generated_text/')
+GENERATED_IMAGE_DIR = mk_dir(TMPDIR + 'generated/')
+GENERATED_TEXT_DIR = mk_dir(TMPDIR + 'generated_text/')
# Make sure we have permissions to access these
assert_writable_dir(CACHEDIR)
@@ -85,12 +85,12 @@ assert_writable_dir(GENERATED_IMAGE_DIR)
assert_writable_dir(GENERATED_TEXT_DIR)
# Flat file directories
-GENODIR = flat_files('genotype')+'/'
+GENODIR = flat_files('genotype') + '/'
assert_dir(GENODIR)
# assert_dir(GENODIR+'bimbam') # for gemma
# JSON genotypes are OBSOLETE
-JSON_GENODIR = flat_files('genotype/json')+'/'
+JSON_GENODIR = flat_files('genotype/json') + '/'
if not valid_path(JSON_GENODIR):
# fall back on old location (move the dir, FIXME)
JSON_GENODIR = flat_files('json')
@@ -98,4 +98,4 @@ if not valid_path(JSON_GENODIR):
# Are we using the following...?
PORTADDR = "http://50.16.251.170"
INFOPAGEHREF = '/dbdoc/%s.html'
-CGIDIR = '/webqtl/' #XZ: The variable name 'CGIDIR' should be changed to 'PYTHONDIR'
+CGIDIR = '/webqtl/' # XZ: The variable name 'CGIDIR' should be changed to 'PYTHONDIR'
generated by cgit v1.2.3 (git 2.44.0) at 2024-10-20 21:03:12 +0000