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<title>PowerPoint Presentation - Complex trait analysis, develop-ment, and
genomics</title>
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content="Jun-19-03: Is there known biology to link Hars2 with App? ">
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mso-text-indent-alt:0'><span style='font-size:68%'><i>Is there known biology to
link Hars2 with App? </i></span></div>
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<div><span style='font-size:150%;color:#E9EB5D;mso-color-index:3'><b>69 SNPs, 1
cSNP: <br>
</b></span></div>
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<div><span style='font-size:150%;color:#E9EB5D;mso-color-index:3'><b>6 exons in
NCBI, <br>
</b></span></div>
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<div><span style='font-size:150%;color:#E9EB5D;mso-color-index:3'><b>2 exons in
Celera</b></span></div>
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mso-text-raise:0%'><span style='font-family:"Gill Sans";font-size:250%;
color:#E9EB5D'><i><span style="mso-spacerun: yes"> </span>Not obvious</i></span></div>
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<td colspan=1></td>
<td align=left colspan=1><font face=Helvetica size=3>Hars2 is not a well
characterized gene and their is no biology yet to support the hypothesis
that Hars2 modulates gene expression, let alone App expression in specific.
There are also serious database/assembly discrepancies between Celera and
MGSCv3 regarding the genomic organization of this gene. But there appear to
be approximately 69 SNPs in Hars2, one of which results in a substitution.</font><br>
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