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-<html> <head> <meta http-equiv=Content-Type content="text/html; charset=macintosh"> <meta name=ProgId content=PowerPoint.Slide> <meta name=Generator content="Microsoft Macintosh PowerPoint 10"> <link id=Main-File rel=Main-File href="WebQTLDemo.htm"> <title>PowerPoint Presentation - Complex trait analysis, develop-ment, and genomics</title> <link title="Presentation File" type="application/powerpoint" rel=alternate href=WebQTLDemo.ppt> <script>
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-</script> <meta name=Description content="Jun-19-03: Tissue differences in probe performance"> <link rel=Stylesheet href="master03_stylesheet.css"> <style media=print> <!--.sld {left:0px !important; width:6.0in !important; height:4.5in !important; font-size:76% !important;} --> </style> <script language=JavaScript src=script.js></script><script language=JavaScript><!--
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-</script> </head> <body style='margin:0px;background-color:black' onclick="DocumentOnClick(event)" onresize="_RSW()" onkeypress="_KPH(event)"> <div id=SlideObj class=sld style='position:absolute;top:0px;left:0px; width:755px;height:566px;font-size:16px;background-color:#484848;clip:rect(0%, 101%, 101%, 0%); visibility:hidden'><img src="master03_background.gif" v:shapes="_x0000_s1026" style='position:absolute;top:0%;left:0%;width:100.0%;height:100.0%'><img border=0 src="slide0024_image101.gif" alt="Text Box: Tissue differences in probe performance" style='position:absolute; top:0%;left:-.79%;width:8.21%;height:89.92%'><img border=0 src="slide0024_image102.gif" style='position:absolute;top:58.48%;left:6.88%; width:62.78%;height:39.22%'> <div class=O style='position:absolute;top:17.66%;left:74.3%;width:21.32%; height:7.77%'><span style='font-family:"Gill Sans";font-size:300%;color:#E9EB5D'><i>Forebrain</i></span></div> <div class=O style='position:absolute;top:79.5%;left:74.3%;width:22.64%; height:7.77%'><span style='font-family:"Gill Sans";font-size:300%;color:#E9EB5D'><i>Stem cells</i></span></div> <img border=0 src="slide0024_image103.gif" style='position:absolute;top:28.97%; left:6.75%;width:62.78%;height:36.21%'><img border=0 src="slide0024_image104.gif" style='position:absolute;top:0%;left:6.62%; width:63.04%;height:36.39%'> <div class=O style='position:absolute;top:51.06%;left:73.5%;width:25.56%; height:7.77%'><span style='font-family:"Gill Sans";font-size:300%;color:#E9EB5D'><i>Cerebellum</i></span></div> </div> <div id=NotesObj style='display:none'> <table style='color:white' border=0 width="100%"> <tr> <td width=5 nowrap></td> <td width="100%"></td> </tr> <tr> <td colspan=1></td> <td align=left colspan=1><font face=Verdana size=3>The vertical text says it all: Even when using identical probes, mapping performance (and signal) depends on tissue type and mRNA complexity. This is another gene in the Hars2 interval. Forebrain and tem cell mRNAs were run on the same U74Av2 array, whereas the cerebellum mRNA was run on the 430A and 430B array set.</font><br> </td> </tr> </table> </div> <script language=JavaScript><!--
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