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-<html> <head> <meta http-equiv=Content-Type content="text/html; charset=macintosh"> <meta name=ProgId content=PowerPoint.Slide> <meta name=Generator content="Microsoft Macintosh PowerPoint 10"> <link id=Main-File rel=Main-File href="WebQTLDemo.htm"> <title>PowerPoint Presentation - Complex trait analysis, develop-ment, and genomics</title> <link title="Presentation File" type="application/powerpoint" rel=alternate href=WebQTLDemo.ppt> <script>
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-</script> </head> <body style='margin:0px;background-color:black' onclick="DocumentOnClick(event)" onresize="_RSW()" onkeypress="_KPH(event)"> <div id=SlideObj class=sld style='position:absolute;top:0px;left:0px; width:755px;height:566px;font-size:16px;background-color:#484848;clip:rect(0%, 101%, 101%, 0%); visibility:hidden'><img src="master03_background.gif" v:shapes="_x0000_s1026" style='position:absolute;top:0%;left:0%;width:100.0%;height:100.0%'> <div style='position:absolute;top:1.41%;left:3.31%;width:105.43%;height:14.66%; filter:DropShadow(Color=#000000, OffX=1, OffY=1)'> <div class=B style='mso-line-spacing:" 0 ";mso-margin-left-alt:292;mso-text-indent-alt: 0;position:absolute;top:0%;left:1.0%;width:98.99%;height:50.6%'><span style='mso-special-format:nobullet;display:none;color:#FBFDB8;font-family:"Monotype Sorts"; font-size:99%'>l</span><span style='font-size:106%;color:#E9EB5D;mso-color-index: 3'>2.45 billion scatter plots: </span><span style='font-size:94%;color:#E9EB5D; mso-color-index:3'>here is one of the best</span></div> </div> <img border=0 src="slide0012_image017.gif" style='position:absolute;top:11.3%; left:6.62%;width:67.41%;height:82.68%'> <div class=O style='position:absolute;top:77.56%;left:41.19%;width:8.6%; height:7.42%'><span style='font-family:"Gill Sans";font-size:283%;color:#003399; mso-color-index:4'><i>App</i></span><span style='font-family:"Gill Sans"; font-size:283%;color:#E9EB5D;mso-color-index:3;mso-special-format:lastCR; display:none'><i><br> </i></span></div> <img border=0 src="slide0012_image018.gif" alt="Text Box: Hsp84-1" style='position:absolute;top:36.04%;left:14.17%;width:6.88%;height:27.03%'></div> <div id=NotesObj style='display:none'> <table style='color:white' border=0 width="100%"> <tr> <td width=5 nowrap></td> <td width="100%"></td> </tr> <tr> <td colspan=1></td> <td align=left colspan=1><font face=Helvetica size=3>The correlation between App and heat shock protein 84-1 transcript is most impressive.<span style="mso-spacerun: yes">&nbsp; </span>Since WebQTL now contains total of about 70,000 traits in the BXD strains, we could produce as many as to 70k x 35k scatter plots of this type. Since all of the<span style="mso-spacerun: yes">&nbsp; </span>correlations come for a common reference population, none<span style="mso-spacerun: yes">&nbsp; </span>of the correlations are blantantly silly. However the great majority may be uninterpretable and a very large number may be meaningless given the signal-to-noise ratios of some measurements. With about 30 strains, correlations above 0.7 have a reasonably low false positive rate.</font><br> </td> </tr> </table> </div> <script language=JavaScript><!--
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