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diff --git a/web/dbdoc/NCSU_DrosWB_LC_RMA_0111.html b/web/dbdoc/NCSU_DrosWB_LC_RMA_0111.html deleted file mode 100755 index 13a66472..00000000 --- a/web/dbdoc/NCSU_DrosWB_LC_RMA_0111.html +++ /dev/null @@ -1,96 +0,0 @@ -<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0 Transitional//EN"> -<HTML><HEAD><TITLE>NCSU Drosophila Whole Body (Jan11) RMA</TITLE> -<META http-equiv=Content-Type content="text/html; charset=iso-8859-1"> - -<LINK REL="stylesheet" TYPE="text/css" HREF='/css/general.css'> -<LINK REL="stylesheet" TYPE="text/css" HREF='/css/menu.css'> -<link rel="stylesheet" media="all" type="text/css" href="/css/tabbed_pages.css" /> -<SCRIPT SRC="/javascript/webqtl.js"></SCRIPT> - -<SCRIPT SRC="/javascript/dhtml.js"></SCRIPT> - -<script src="/javascript/tabbed_pages.js" type="text/javascript"></script> - -</HEAD> -<BODY bottommargin="2" leftmargin="2" rightmargin="2" topmargin="2" text=#000000 bgColor=#ffffff > - -<TABLE cellSpacing=5 cellPadding=4 width="100%" border=0> - <TBODY> - <TR> - <script language="JavaScript" src="/javascript/header.js"></script> - </TR> - <TR> - <TD bgColor=#eeeeee class="solidBorder"> - <Table width= "100%" cellSpacing=0 cellPadding=5> - <TR> - - <!-- split from Here --> - <!-- Body Start from Here --> - <P class="title">NCSU Drosophila Whole Body (Jan11) RMA <BR>Accession number: <A HREF="/webqtl/main.py?FormID=sharinginfo&GN_AccessionId=297">GN297</A> <A HREF="/webqtl/main.py?FormID=editHtml"> - <img src="/images/modify.gif" alt="modify this page" border= 0 valign="middle"></A></P> -<blockquote> -<p class="subtitle">Summary:</p> -<p>Determining the genetic architecture of complex traits is challenging because phenotypic variation -arises from interactions between multiple, environmentally sensitive alleles. We quantified genomewide -transcript abundance and phenotypes for six ecologically relevant traits in D. melanogaster -wild-derived inbred lines. We observed 10,096 genetically variable transcripts and high heritabilities -for all organismal phenotypes. The transcriptome is highly genetically inter-correlated, forming 241 -transcriptional modules. Modules are enriched for transcripts in common pathways, gene ontology -categories, tissue-specific expression, and transcription factor binding sites. The high transcriptional -connectivity allows us to infer genetic networks and the function of predicted genes based on -annotations of other genes in the network. Regressions of organismal phenotypes on transcript -abundance implicate several hundred candidate genes that form modules of biologically meaningful -correlated transcripts affecting each phenotype. Overlapping transcripts in modules associated with -different traits provides insight into the molecular basis of pleiotropy between complex traits.<br> -<A HREF="http://www.nature.com/ng/journal/v41/n3/abs/ng.332.html" target="_blank">Full Article</A></p> -<p class="subtitle">Animals and Tissue Used to Generate This Set of Data:</p> -<p>The raw microarray data are deposited in the ArrayExpress database (<A HREF="http://www.ebi.ac.uk/arrayexpress/browse.html?keywords=E-MEXP-1594&expandefo=on">www.ebi.ac.uk/arrayexpress,</A>) under accession -number E-MEXP-1594</p> -</blockquote> - - </TR></TABLE> - </TD> - </TR> - <TR> - <TD align=center bgColor=#ddddff class="solidBorder"> - <!--Start of footer--> - <TABLE width="90%"> - <script language='JavaScript' src='/javascript/footer.js'></script> - <TR> - <TD colspan=3 class="fs12"> - <UL> - - </UL> - </TD> - </TR> - </TABLE> - <!--End of footer--> - </TD> - </TR> -</TABLE> -<!-- /Footer --> -<!-- menu script itself. you should not modify this file --> -<script language="JavaScript" src="/javascript/menu_new.js"></script> -<!-- items structure. menu hierarchy and links are stored there --> -<script language="JavaScript" src="/javascript/menu_items.js"></script> -<!-- files with geometry and styles structures --> -<script language="JavaScript" src="/javascript/menu_tpl.js"></script> -<script language="JavaScript"> - <!--// - // Note where menu initialization block is located in HTML document. - // Don't try to position menu locating menu initialization block in - // some table cell or other HTML element. Always put it before </body> - // each menu gets two parameters (see demo files) - // 1. items structure - // 2. geometry structure - new menu (MENU_ITEMS, MENU_POS); - // make sure files containing definitions for these variables are linked to the document - // if you got some javascript error like "MENU_POS is not defined", then you've made syntax - // error in menu_tpl.js file or that file isn't linked properly. - - // also take a look at stylesheets loaded in header in order to set styles - //--> - -</script> -</BODY> -</HTML> |