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diff --git a/web/dbdoc/NCSU_DrosWB_LC_RMA_0111.html b/web/dbdoc/NCSU_DrosWB_LC_RMA_0111.html new file mode 100755 index 00000000..13a66472 --- /dev/null +++ b/web/dbdoc/NCSU_DrosWB_LC_RMA_0111.html @@ -0,0 +1,96 @@ +<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0 Transitional//EN"> +<HTML><HEAD><TITLE>NCSU Drosophila Whole Body (Jan11) RMA</TITLE> +<META http-equiv=Content-Type content="text/html; charset=iso-8859-1"> + +<LINK REL="stylesheet" TYPE="text/css" HREF='/css/general.css'> +<LINK REL="stylesheet" TYPE="text/css" HREF='/css/menu.css'> +<link rel="stylesheet" media="all" type="text/css" href="/css/tabbed_pages.css" /> +<SCRIPT SRC="/javascript/webqtl.js"></SCRIPT> + +<SCRIPT SRC="/javascript/dhtml.js"></SCRIPT> + +<script src="/javascript/tabbed_pages.js" type="text/javascript"></script> + +</HEAD> +<BODY bottommargin="2" leftmargin="2" rightmargin="2" topmargin="2" text=#000000 bgColor=#ffffff > + +<TABLE cellSpacing=5 cellPadding=4 width="100%" border=0> + <TBODY> + <TR> + <script language="JavaScript" src="/javascript/header.js"></script> + </TR> + <TR> + <TD bgColor=#eeeeee class="solidBorder"> + <Table width= "100%" cellSpacing=0 cellPadding=5> + <TR> + + <!-- split from Here --> + <!-- Body Start from Here --> + <P class="title">NCSU Drosophila Whole Body (Jan11) RMA <BR>Accession number: <A HREF="/webqtl/main.py?FormID=sharinginfo&GN_AccessionId=297">GN297</A> <A HREF="/webqtl/main.py?FormID=editHtml"> + <img src="/images/modify.gif" alt="modify this page" border= 0 valign="middle"></A></P> +<blockquote> +<p class="subtitle">Summary:</p> +<p>Determining the genetic architecture of complex traits is challenging because phenotypic variation +arises from interactions between multiple, environmentally sensitive alleles. We quantified genomewide +transcript abundance and phenotypes for six ecologically relevant traits in D. melanogaster +wild-derived inbred lines. We observed 10,096 genetically variable transcripts and high heritabilities +for all organismal phenotypes. The transcriptome is highly genetically inter-correlated, forming 241 +transcriptional modules. Modules are enriched for transcripts in common pathways, gene ontology +categories, tissue-specific expression, and transcription factor binding sites. The high transcriptional +connectivity allows us to infer genetic networks and the function of predicted genes based on +annotations of other genes in the network. Regressions of organismal phenotypes on transcript +abundance implicate several hundred candidate genes that form modules of biologically meaningful +correlated transcripts affecting each phenotype. Overlapping transcripts in modules associated with +different traits provides insight into the molecular basis of pleiotropy between complex traits.<br> +<A HREF="http://www.nature.com/ng/journal/v41/n3/abs/ng.332.html" target="_blank">Full Article</A></p> +<p class="subtitle">Animals and Tissue Used to Generate This Set of Data:</p> +<p>The raw microarray data are deposited in the ArrayExpress database (<A HREF="http://www.ebi.ac.uk/arrayexpress/browse.html?keywords=E-MEXP-1594&expandefo=on">www.ebi.ac.uk/arrayexpress,</A>) under accession +number E-MEXP-1594</p> +</blockquote> + + </TR></TABLE> + </TD> + </TR> + <TR> + <TD align=center bgColor=#ddddff class="solidBorder"> + <!--Start of footer--> + <TABLE width="90%"> + <script language='JavaScript' src='/javascript/footer.js'></script> + <TR> + <TD colspan=3 class="fs12"> + <UL> + + </UL> + </TD> + </TR> + </TABLE> + <!--End of footer--> + </TD> + </TR> +</TABLE> +<!-- /Footer --> +<!-- menu script itself. you should not modify this file --> +<script language="JavaScript" src="/javascript/menu_new.js"></script> +<!-- items structure. menu hierarchy and links are stored there --> +<script language="JavaScript" src="/javascript/menu_items.js"></script> +<!-- files with geometry and styles structures --> +<script language="JavaScript" src="/javascript/menu_tpl.js"></script> +<script language="JavaScript"> + <!--// + // Note where menu initialization block is located in HTML document. + // Don't try to position menu locating menu initialization block in + // some table cell or other HTML element. Always put it before </body> + // each menu gets two parameters (see demo files) + // 1. items structure + // 2. geometry structure + new menu (MENU_ITEMS, MENU_POS); + // make sure files containing definitions for these variables are linked to the document + // if you got some javascript error like "MENU_POS is not defined", then you've made syntax + // error in menu_tpl.js file or that file isn't linked properly. + + // also take a look at stylesheets loaded in header in order to set styles + //--> + +</script> +</BODY> +</HTML> |