diff options
| -rwxr-xr-x | web/genotypes/B6D2F2.geno | 647 | ||||
| -rwxr-xr-x | wqflask/base/data_set.py | 2 | ||||
| -rwxr-xr-x | wqflask/wqflask/do_search.py | 11 | ||||
| -rwxr-xr-x | wqflask/wqflask/marker_regression/marker_regression.py | 224 | ||||
| -rw-r--r-- | wqflask/wqflask/my_pylmm/pyLMM/lmm.py | 8 | ||||
| -rw-r--r-- | wqflask/wqflask/static/new/css/scatter-matrix.css | 40 | ||||
| -rw-r--r-- | wqflask/wqflask/static/new/javascript/scatter-matrix.js | 2 | ||||
| -rw-r--r-- | wqflask/wqflask/static/packages/bootstrap/fonts/glyphicons-halflings-regular.eot | bin | 0 -> 20335 bytes | |||
| -rw-r--r-- | wqflask/wqflask/static/packages/bootstrap/fonts/glyphicons-halflings-regular.svg | 229 | ||||
| -rw-r--r-- | wqflask/wqflask/static/packages/bootstrap/fonts/glyphicons-halflings-regular.ttf | bin | 0 -> 41280 bytes | |||
| -rw-r--r-- | wqflask/wqflask/static/packages/bootstrap/fonts/glyphicons-halflings-regular.woff | bin | 0 -> 23320 bytes |
11 files changed, 726 insertions, 437 deletions
diff --git a/web/genotypes/B6D2F2.geno b/web/genotypes/B6D2F2.geno index 2b02a2f0..6e76d10c 100755 --- a/web/genotypes/B6D2F2.geno +++ b/web/genotypes/B6D2F2.geno @@ -1,323 +1,324 @@ -#this is B6D2F2 genotype file, it should be tab-delimited -#the first three/four columns should be "Chr, Locus, cM, [Mb]" (case sensitive) -#please save as Unix format text file. -#comment line always start with a '#' -#type riset or intercross -@type:intercross -@name:B6D2F2 -#abbreviation of maternal or paternal parents -@mat:B -@pat:D -#heterozygous , optional, default is "H" -@het:H -#Unknown , optional, default is "U" -@unk:U -Chr Locus cM Mb CASE001 CASE002 CASE003 CASE004 CASE005 CASE006 CASE007 CASE008 CASE009 CASE010 CASE011 CASE012 CASE013 CASE014 CASE015 CASE016 CASE019 CASE020 CASE021 CASE022 CASE023 CASE024 CASE025 CASE027 CASE028 CASE030 CASE031 CASE032 CASE033 CASE034 CASE035 CASE036 CASE037 CASE038 CASE039 CASE040 CASE041 CASE042 CASE043 CASE044 CASE046 CASE047 CASE048 CASE050 CASE051 CASE052 CASE053 CASE054 CASE055 CASE056 CASE057 CASE058 CASE059 CASE060 CASE062 CASE063 -#Y DYCTC3.3411 1 0.891414 B F B F F F B F B F F B D B F B F F F B F B D B D B F B D D F B F B F F F F B F B B F B B F F B D B B B B B F F -#Y DYCTC8.8315 3 3.360446 B F B F F F B F B F F B D B F B F F F B F B D B D B F B D D F B F B F F F F B F B B F B B F F B D B B B B B F F -#M UT-M-9461 0 0.009462 B B B B B B B D B B D B D B B B D B D B B B D B D B B B D D B B D B B D D B B D B B B B B B B B D B B B B B B B1 D1Mit118 8.3 3.959096 B H H H H H B B H B B H H B D D H H H H B B B D H H D D H H H H H B H B D B B B H B H H D D D H B D B H H H H H -1 D1Mit430 10 14.271355 B H H H H H B B H B H H H B D D H H H H B B B D H H D D H H H H D B H B D H B H H H B H D D D H B D B H H H H H -1 D1Mit373 17 26.535325 B H H D H H B B H B H H H H D D H H H H B B H D H D H D H H H H D H H H D H B H H H B H D D D H B D B H H H H H -1 D1Mit171 20.2 36.800666 B H H D H D H H H B H H H H D D B H H H B B H D H D H D D H H H D H H H D H B H H H B H D D D H B D B H H H H H -1 D1Mit236 25.7 45.435457 B H H D H D H H D B H B H H D D B H H H B H H D H D H D D H H H D H H H H H H H H H H H D D D H B B B H H H H H -1 D1Mit214 32.1 58.290808 B D H D D H H H D B H B H H H D B H H H B H H D H D H D D H H H D H H H H H H H H H H H D D D H B B H H H H H H -1 D1Mit300 32.8 63.927416 B D H D D H H H D B H B H H H D B H H H B H B D H D H D D H H H D H H H H H H H H H H H D D D H B B H H H H H H -1 D1Mit282 36.7 73.273628 B D H D D H H H D B H B H H H D B H H H B H H D H D H D D H H H D H D H H H H H H H H H H D D H B B H H D H H H -1 D1Mit80 53 88.274502 B D H H D H H H D H D B H H H D B B H H B H H D H D B D H H H B D H D H H D H H H H H H H D D H H B H H D H H H -1 D1Mit48 54 90.464814 B D H H D H H H D H D B H H H D B B H H B H H D H D B D H H H B D H D H H D H H H H H H H D D H H B H H D H H H -1 D1Mit45 58.5 94.909763 H D H H H H H H D H D B H H H D B B H H B H H D H D B D B H H B D H D H H D H H H H H H H D D H H B H H D H H H -1 D1Mit135 61 107.206162 H D H H H H H H D H D B H H H D B B H H B H H D H D B D B H H B D H D H B D H H H H H H H D D H H B H B D H H H -1 D1Mit387 62 117.229212 H D H H H H H H D H D B H H H D B B H H B H H D H H B D B H H B D H D H B D H H H H H H H D D H H B H B D H H H -1 D1Mit91 64 128.355209 H D H H H H H H D H D B H H B D B B H H B H H D H H B D B H H B D H D H B D H H H H H H H D H H H B H B D H H H -1 D1Mit103 73 137.882255 H D H H H H H H H H D B H H B D B B H H B H H D H H B D B D H B D H D H B D H H H H H H H D H H H B H B D H H H -1 D1Mit265 74.3 150.686863 H D H H H H H H H D D B H H B D B B H H B H D D B H B H B D H B D H D H B D H H H H H H H D H H H B H B D H H H -1 D1Mit14 74.5 158.704597 H D H H H H H H H D D B H H B D B B D H B H D D B H B B B D H B D H D H B D H H H H H H H D H H H B H B D H H H -1 D1Mit57 87.8 168.634127 H D H H H H H H H D D B H H B D B B D H H H D D B H B B B D H H D H D H B D H H H H H H H D H H H B H B D H H H -1 D1Mit113 93.2 173.73461 H D H H B H H H H D D B H H B H B B D H H H D D B B B B H D H D D H H H B D B H H H H H H D H H H B H B D H H H -1 D1Mit206 95.8 174.934328 H D H H B D H H H D D B H H B H B B D H H H D D B B B B H D H D D H H H B D B H H H H H H D H H H B H B D H H H -1 D1Mit426 101 182.341751 H D H H B D H D H D D B H H B H B B H H H H D D B B B B H D H D H H H H B D B D H D H H H D H H D B H B D H H H -1 D1Mit155 112 196.255162 H D B H B D H D H D H D H H B B H B H H H H D D B B B B H D H D H D H H H D B D H H H D H H H H D B H H D B B H -2 D2Mit1 1 3.80336 B D H H B H B H B H H H D H B H H B B H H H D H H H D B H B H H D H H H B B D H H H H H D B H D D D H B D H H B -2 D2Mit464 10.9 18.517336 B D H H B H H H B H B H D H H H B B B H H H D H H H D B H B H H D D H H B B D D D H H H D H H H D H H B D H H H -2 D2Mit6 12 20.814593 B D H H B H H H B H B H D H H H B B B H H H D H H H D B H B H H D D H H B B D D D H H H D H H H D H H B D H H H -2 D2Mit80 12 20.928231 B D H H B H H H B H B H D H H H B B B H H H D H H H D B H B H H D D H H B B D D D H H H D H H H D H H B D H H H -2 D2Mit235 22.5 32.753979 B D H D B H H D B H B D D D H H B B B H H H D H H D D B H B H H D D H H B B D D D H H H D H H H D H H B D H H D -2 D2Mit238 28 33.976569 B D H D B H H D B H B D D D H H B B B H H H D H H D D B H B H H D D H H B B D D D H H H D H H H D H H B D H H D -2 D2Mit237 30 40.851 B D H D B H H D B H B D H D D H B B B H H H D H H D D B H B H H D D H H B B D D D H H H D H H H D H H B D H H D -2 D2Mit458 31.7 50.709674 B D H D B H H D H H B D H D D H B B B H H H D D H D D B H B H H D D H H B B D D D H H H D D D B D H H B D H H D -2 D2Mit61 36 60.528324 B D H D B H H H H H B D H D D B B B B D H H H D H D H B H H H H D D H H B H D D D H H B D D D B D B B B D B H D -2 D2MIt37 45 74.531829 B D H D B H H H D H B D H D D D H B H D H H B D H H B B H H H H H D H B B H D H H H H B D D D B D B B B D B H H -2 D2Mit66 47.5 84.657699 H D H D B H D H D H B H H D D D H B H D H H B D H H B B H H H H B D H B H H D H H H H B D D D B D B B B D H H H -2 D2Mit45 53 91.783197 H D H D B H D H D H B H H H D H H B H D H H B D H H B B H H D H B D H B H H D H H H H B D D D B D B B B D H H H -2 D2Mit12 53 102.941478 H D H D B H D H D D H H H H D H H B H D H H B D H H B B H H D H B D H B H H D B H H B B D D D B D B B B D H H H -2 D2Mit58 53.4 108.099785 H D H D B H D H D D H H H H D H H B H D D H B D H H B B H H D H B D H B H H D B H H B B D D D B D B B B D H H H -2 D2Mit484 55 118.399165 H D H D B H D H D D H H H H D H H B H D D B B D B H B B H D D H B D H B H H H B H H B B D D D B H B B H D H D H -2 D2Mit164 69.5 123.215788 H D H D B H D H D D H H H H D H H B H D D B B D B H B B H D D H B D H B H H H B H H B B D D D B H B B H D H D H -2 D2Mit223 71 134.813146 H D H H B B D H D D H H H H D H H B H D D B B D H H B B H D D H B H H B H H H B H D B B D D D B H B B H D H H B -2 D2Mit403 72 144.499676 H D H H B B D H D H H H H H D H H B H D D B B D H H B B H D D H B H H B H H H B H D B B D D D B B B B H D H H H -2 D2Mit286 74 154.338344 H H H B B B H H D H H H H H D H H B H D D B B D H H B B H D D H B H H B H H H B H D B B D D D B B B B H D H H H -2 D2Mit50 80 162.50259 H H H B B B H H D H H H H H D H H B H D D B B D H H B B H D D D B B H B D H B B H H B B D D D B B H H H H H H B -2 D2Mit311 83.1 165.648472 H H H B B B H H D H H H H H D H H B H D D B B D H H B B H D H D B H H B D H B B D D B B D D D B B D H H H H H B -2 D2Mit148 105 178.535249 H H B B B B H B H H H B H H D H H H H D H B B D H D H B H D H D H H H B H H B H D D H B D D H B B D H H H H H B -3 D3Mit221 2.4 7.891492 H H H H B D H H B D H D H H H D H D D H D H B B H H H B H B H H H D H B H H H D H D B B B H D H B H B B H H D H -3 D3Mit62 4.6 17.467422 D H H D B D H H B D H D H H H D H H D H D H B B H H H B H B H H H D B B H B H D H D B B B H D B B H B H H H H H -3 D3Mit305 11.2 27.097878 D H H D B H H H B D B D H H H D H H D H D H B B H H H B H B H H H D H B H B H D H D B B B H D B H H B H H H H H -3 D3Mit151 18.5 31.137264 D H H D B H H H B D B D H H H D H H D H D H B B H H H B H B H H H D H B H B H D H D B B B H D B H H B H H H H H -3 D3Mit63 21.5 40.846321 D H H D B H H H B H B D H H H H H H D H D H B H H H H B H B H H H H H B H B H H H D B B H H D B H H B D H B H H -3 D3Mit65 23.3 50.488799 D H H D B H H H B H B D H H H H H H D H D H B H H H H B H B H H D H H B B B H H H D B B H H D B H H B D H B H H -3 D3Mit185 29.5 57.246564 D H H D B H H D B H B D H H B H H H D H D H H H B D H B H B D H D H H H B B H H H D B B D H D B H H H D H B H H -3 D3Mit154 33 68.61339 D H H D B H H D B H B H H B B H H H D H D H D H B D B B H B H H D H D H B H H H H D B B D H D B H H H D B B H H -3 D3Mit51 35.2 76.80336 D H H D B H H D H H B H H B B H H D D H D H D H B D B B H B H H D H D H B H H H H D B B D H D B H H H D B B H H -3 D3Mit187 42.4 87.067071 D H H D B H H D H H B H H B B H H D D H D H D H B D B B H B H H D H D H B H H H H D B B D H D B H H H D B B H D -3 D3Mit156 45.2 92.359916 D H H D B H H H H H B H H B B H H D D H D D D H B D B B H B H H D H D H B H H H H D B B D H D B H H H D B B H D -3 D3Mit76 45.2 94.832825 D H H D B H H H H H B H H B B H H D D H D D D H B D B B H B H H D H D H B H H H H D B B D H D B H H H D B B H D -3 D3Mit189 50 100.779518 D H H D B H H H H H B H H B B H D D D H D D D H B D B B H B H H D H D H B H H H H D B B D H D B H H H D B B D D -3 D3Mit78 55 111.166674 D H H D B B H H H H B H H B B H D D D B D D D H B D B B H B H H H B D H B H H H H D B B H H D B H H H D B B D D -3 D3Mit43 58.8 121.164708 D H H H B B H H H H H H H B B H D D D H H D D H B D B B H B H H H B D H B H H H H D B H H H D H H D H D B B D D -3 D3Mit14 65 131.693819 D H H H B B H H H H H H H B B H D D D H H D D H B D B B D B H H H B D H B H H H H D B H H D D B H D H D B B D D -3 D3Mit17 71.8 143.310188 D H H H B B H B H D H H H B B H H D D H H D D H B D B B D B H H H B D H H H H H H H H H H D D B D D H D B B H D -3 D3Mit147 79.4 148.408372 D H H H H B H B H D H H H B B H H D D H B D D H B D H B D B H H H B D H H H D H H H H H H D D B D D H D B B H D -3 D3Mit89 87.7 156.500068 D H D H H B D B B D H H H B B H H D H H B D D H H D H B D B H H H B D H H H D H H H H H H D H B D D H H B B H D -3 D3Mit19 87.7 157.646003 D H H H H B D B B D H H H B B H H D H H B D D H H D H B D B H H B B D H H H D H H H H H H D H B D D H H B B H D -4 D4Mit149 0 3.58427 H H B H D B H B B B D B H D B B B D H H B B B H H H B H H H H B H H H B B H H H B D H H H H D B D H H D H B B B -4 D4Mit101 3.2 9.629759 H H B H D B H B B B D B H D B B B D H H B B B H H H B H H H B H H H H B B D H H B D H H H H D B D H H D D B B B -4 D4Mit171 6 22.41343 H B H H D B H B B B D B H D B B B H H H B B B H H H B H H H B H H H H B B H H H B D H H H H H B D H H D D B B B -4 D4Mit192 6.3 31.064208 H B H H D B H B B B D B H D B B B H H H B H B H H H B H H H B H H B H B B H H H B D H H H H H B D H H D D B B B -4 D4Mit172 10 34.342408 H B H H H B H B B B D B H D B B B H H H B H D H H H B H H H B H H B H B B H D H B D H H H H H B D H H D D B B B -4 D4Mit214 17.9 45.671313 H B H H H H H H B B D B H D B B B H H H H H D H D H H D H H B H H B H B B H D H B D D H H H H B D H H D D B B B -4 D4Mit111 21.9 53.56371 H B H H H H H H B B D B H D B B B H H H H H D B D D H D H H B H H B H B B H D H B D D H H H H B D D H D D B B B -4 D4Mit178 35.5 66.843058 D B H H H H D H D B D B H D B B B H B H H H D B D H H D D D B H H B H B B H D H H D D H H H H B D D H D D B B B -4 D4Mit142 37.5 73.86524 D B H H H H D D D B D B H D B B B H B H H H D B D H H D D D B H D B H B B H D H H D D H H D H B D D B D D B B H -4 D4Mit297 38 80.923505 D B H H H H D D D B D B H D B B B H B H H D D B D H H D D D B H D B H B B H D H H D D D B D B B D D B D D B B H -4 D4Mit186 44 90.81234 D B H H H H D D D B D H D D B B B H B H H D D B D H H D D D B H D B H B B H D H D D D D B D B B D D B D H B B H -4 D4Mit255 48.5 98.887399 H H H H H H D D D B H H D D B B B B B H H D D B D H H D D D B H D B B B B H D H D H D D B D B B D D B D H H B H -4 D4Mit146 53.6 109.473539 H H H H H H D D D H H H D H B B B B B H H D D B D H H D D D B H D B B B B H D H D H D D B D B B D D B D H H D H -4 D4Mit332 53.6 114.164598 H H H H H H D D D H H H D H B B B B B H H D D B D H H D D D B H D B B B B H D H D H D H B D B B D D B D H H D H -4 D4Mit37 56.5 116.887378 H H H H H H D D D H H H D H B B B B B D H D H B H H H D D D B H D B B B B H D H D H D H B D B B D D B D H H D H -4 D4Mit334 57 119.383705 H H H H H H D D D H H H D H B B B B B D H D H B H H H D D D B H D B B B B H D H D H D H B D B B D D B D H H D H -4 D4Mit203 60 129.249261 H H H H H H D D D H H H D H B B B B B D H D H H H H H D D H B H D H B B B D D H D H D H B D B H D D B D H H D H -4 D3Mit54 4.6 135.130158 H H H D B D H H B D H D H H H D H H D H D H B B H H H B H B H H H D B B H B H D H D B B B H D H B H B H H H D H -4 D4Mit312 69.8 141.449884 H D H H H H H D D H H H D H D B B B B D H D B H H H H D D H B H D H H B B D H H D H D H B D B H D D B H H H D D -4 D4Mit42 81 150.944102 H D H H H H H D H H H H D H D B B B B D B D B H H H H D D H H B D H H H B D H H D B D H H D B H D D H H H H D D -5 D5Mit346 0.5 4.879512 H H D B D D D H H B D B H H H H H B B H H D B D D D H H H B H H D H H H D D D H B D D D H D H H D H D H B H B H -5 D5Mit294 8 20.863134 H H D B D D D B H B D B H H H H D B B D H D B D H D H H H B H H H H B H H D D H B D D D H D H H D H D H B B B D -5 D5Mit348 8 24.424936 H H D H D D D B H B H B H H H H D B B D H D B D H D H H B B H H H H B H H D D H B D D D H D H H D H D H B B B D -5 D5Mit352 20 35.957615 H H D H D D D B B B H B H H H H D B B D H D B D H D H H B H H H H H B H H D D H H H D D H D H H D H D H H B B D -5 D5Mit267 23 40.977741 H H D H D D D B B H H B H H H H D B B D D D B D H D H H B H H H H H B H H D D H H H D D H D H H D H D H H B B D -5 D5Mit255 30 55.345577 H H D H D D D B B H H B H H H H H H B D D D D D H D H H B H B H H H B H H D D H H H D D H D H H H H D H H B B D -5 D5Mit197 36 65.040326 H H D H D D D B B H H B H H H H H H B D D D D D H H H H B H B H H H B H H D D H H H D D H D H H H H H H H B B D -5 D5Mit356 41 73.587246 D H H H D D D B H H H B H H H H H H H D D H D D B H H H B H B H H H B H H H D D H H D D H D H H H H H H H B B D -5 D5Mit309 44 79.931745 D H H H D D D H H H H B H H H H H H H D D H D D B H H H B H B H H H B H H H D D H H D D H D H H H H H H H B B D -5 D5Mit18 50 93.726234 D H H H D D D H H H H B H H H H H H H D D H D D B H H H B H B H H H B H H H D D H H D D H D H H H H H H H B B D -5 D5Mit403 57 106.233589 D H H H D H H H D H H B H H H H H H D D D H D D B D H H B H B H H H B H H H D D H H D D H D H B B H H B H B B H -5 D5Mit25 59.8 114.3337 D H H H D H H H D H H B H H H H H H D D D H D D B D H H B H B H H H B H H H H D H H H D B D H B B H H B H B B H -5 D5Mit95 68.5 125.309604 D H H H D H H D D H H B B H H B H D D H D H D D B D H D B D B H H H H H H H H D D H H D B D H B B H H B H H B B -5 D5Mit139 69 125.93169 D H H H D H H D D H H B B H H B H D D H D H D D B D H D B D B H H H H H H H H D D H H D B D H B B H H B H H B B -5 D5Mit372 73 132.603108 D D H H D H H D D H H B B H H B H D D H D H D D B D H D B D B D H B H D H H H D D H H B B D H B B H D B H H B B -5 D5Mit222 85 142.979299 D D H H D B H D D H D B B H H B H D D H D H D D H D H D H D B D H B H D H H H D D H H B H D D H B H D H H H B H -5 D5Mit223 89 147.662596 D D H H D B H D D H D B B B H B H D D H D H H D H D H D H D B D H B H D H H H D D H H B H D D H B H D H H H B H -6 D6Mit86 0.5 4.414883 D H H D D B B B H B D H H H H H D H D H B H D D D H H D D B D H H D B D H B D H D H H H H B H D D B B H H H H H -6 D6Mit264 3.2 16.618913 D H H D D B B H H B D H H H H H D H D H H H D D D H H D D B D H H D B H H B D H D H H H H B H D D B B H H H H H -6 D6Mit159 7 29.701221 D H D D D B H H B B H H H H H H D D D H H H D D D H H H D B D H H D B H H B D H H H H H H B H D D H B H H H H H -6 D6Mit268 15.5 34.684662 D H D D D B H H B H H H H H H H D B D H B H D D D H H H D B D H H D B H H B D H H H H H H B H D H H B H H H H H -6 D6Mit207 19 44.415869 H H D D D B H D H H H H H H H H D B D H B H D D D B H H D B D H H H B H H B D H H H H B H B H D H H B D H H H B -6 D6Mit74 20.5 48.676554 H H D D D B H D H H H H H H H H D B D H B H D D D B H H D B D H H H B H H B D H H H H B H B H D H H B D H H H B -6 D6Mit93 26.3 52.111711 H H H H D B H D H H H H H H H H D B D H B H D D H B H H H H D H H H B H H B H H H D H B H B H D H H B H H H H B -6 D6Mit316 28.9 55.505942 H H D D D B H D H H H H H H D H D B D H B H D D D B H H H B D D H H B H H B H H H D H B H B H D H H B H H H H B -6 D6Mit175 29.9 64.944267 H H D D D B H D H H H B H H D H D B D H B H D D D B H H H B D D H H B H H B H H H D H B H B H D H H B H H H H B -6 D6Mit188 32.5 75.397576 H H D D D B H D H H H B H H D H D B D H B H H D D B H H H B D D H H B H H B H H H D H B D B H D H H B H H H B B -6 D6Mit69 35 83.5957 H H H D D H H D H H H B H H D H H B D H B H H D D B B H H B D D H H B H H B H H H D H B D B H D H H H H H D B B -6 D6Mit102 38.5 93.413942 H H H H H H H D H H H B H H D H H B D H B H H D D B B H H B D D D H B H H B H H H D H B D B H D H D H H H D B B -6 D6Mit39 45.5 106.519219 H H H H H H H D H H H H H H D H H B D B B H H D D B B H H H D D D H H H H B H D H D H B D H H D H D H H B D B B -6 D6Mit150 51 116.105145 H H H B H H D D H H H H H H D H H B D B B H H H D B B H H H D D D H H H H B H D H B H B D H H D H D H H B D B B -6 D6Mit135 62.3 128.784911 H B B B H H D D H D H H H H H H H B D B B H B H D B B D H H H D H H H H H B H D B B H H D H H D H D B H B D B B -6 D6Mit374 63.7 134.069467 H B B B H H D D H D H H H H H H H B D B B H B H D B B D H H H D D H H H H B H D B B H H D H H D H D H H B D B B -6 D6Mit339 65 136.372096 H B B B H H D D H D H D H H H H H B D B B H B H D B B D H H H D D H H H H B H D B B H H D H H D H D B H B D B B -6 D6Mit201 74.1 146.582002 H B B B B H D D B H H D H H H H H B D B H H B H D B B D H H H D D H H H H B H D H B H H H H H D H D H H B H B B -7 D7Mit178 0 3.463879 H B B H H H D H H D B H D H H B H B B D H B D B H H H D H B H H D D H B D H H H B D D D B H D H H B H B D H H H -7 D7Mit190 2.9 17.644355 H B B H H D D D H D B H D H H B H B B D H H D B H H H H H B H H D D D B D H H H B D D D B H D H H H H H D H H H -7 D7Mit114 8.1 27.523162 H B B H H D D D H D B H D D H H H B B D H H D B H H H H B B B H D D H B D H B H H D D D B H D D H H H H H H H H -7 D7Mit80 18 47.494517 H B B H H H H H H D B H D D D H B H B D H H D B H B H H B B B D D D H B D D B H H D D D B H D D H H H H H H B D -7 D7Mit230 24.5 56.764848 B B B B H H H H B D B H D D D H B H B D H H D B H B H H B B B D D H H B D D B H H D D D H H D D H H H H H H B D -7 D7Mit84 28.4 66.454555 B B H B H H H H B D B H D D D H B H B D H H D B H B H H B B B D D H H B H D B H H D D D H H D D H H H H H H B D -7 D7Mit195 28.5 72.726203 B B H B H H H H B D B H D D D H B H B D H H D B H B H H B B B D D H H B H D B H H D D D H H D D H H H H H H B D -7 D7Mit202 37 83.020513 H B H B H H H H B D B H D H D H B H B H H H D H H B H H B B B H D H H B B H B H H D D D H H D D D H B H H H B H -7 D7Mit350 41 90.734598 H B H B H H H H B D B H D H D H B D B H H H D B H H H H B B B D D H H B B H B H H D D D H H D D D H B H H H B H -7 D7Mit301 46.5 98.73242 H B H B H H H H B D B H D H D H B D B H H H D B H H H H B B B D D H H B B H B B H H D D H H D D D H B H H H B H -7 D7Mit323 50 108.024449 H H H B H H H H B D B H D H D B B D B H H H D B H H H H H B B D D H H B B H B B H H D D H H D D D H B D H H B H -7 D7Mit281 52.4 119.355843 H H H B B H H H B D B H D H D B B D B H H H D B H H H H H B B D D H H B B H B B H H D D H H D D D H B H H D B H -7 D7Mit40 53 123.960955 H H H B B H H B B D B H D H D B B D B H H H D B H H H H H B B D D H H B B H B B H H D D H H D D D H B H H H B H -7 D7Mit66 57.5 127.029509 H H H B B H H B B D B H D H D B B D B H H H D B H H H H H B B D D H H B B H B B H H D D H H D D D H B H H H B H -7 D7Mit12 65.9 143.722526 H H H B B H H B H D B H D H D B H D B B H H D B H H H H D B B D D H H B B H H B H D B D H H H H H D B H D H H B -7 D7Mit334 69 145.481454 H H H B B H H B H H B H D H D B H D B B H H D B H H H H D B B D D H H B B H H B H D B D H H H H H D B H D H H B -7 D7Mit259 72 151.943408 H H H B B D H B H H H H D B D H H D B H H H D H H H H D D B D D D B H B B H H B H D B D H H H H D H B H D H D B -8 D8Mit124 6 14.723159 H H H D H H B H H H B B B D D H H H B H B H B D H B H D H H B D D H B D H D B H H H B H H B H D H H D B B H H D -8 D8Mit335 7 19.165365 H H H D H H B H H H B B B D H H H H B H H H H D H B H D H H B D D H B D H D B H H H B H H B H H H H D B B H H D -8 D8Mit95 8 25.604644 H H H D H H B H H H B B B D H H H H B H H H H D H B H D H H B D D H B D H H B H H H B H H B H H H H D B B H H D -8 D8Mit94 13 32.452129 H H H D H H B H H H B B B D H H H H B H H H H D H B H D H H B D D H B D D H B H H H H H H B H H H H D B B H H D -8 D8Mit294 22.5 40.490764 D H H D B H B H H H B B B H H H H H B B H H H D H B H D H H B D D H B D D H B H H H H H H B H H H H D B B H H D -8 D8Mit100 31 59.139595 D H H H B H H H B H H B H H H H H H B B H H H D H H H D H H B D D H B D D H B H H H H H H B H H H H D B B H H D -8 D8Mit25 32 67.115826 D H H H B H H H B H H B H H H H H H B B H H H H H H H D H H B D D H B D D H B H H H H H H B H H H H D B B H H D -8 D8Mit145 33.7 74.271358 D H H H B H H H B H H B H H H H H H B B H H H H H H H D H H H D D H B D D H B H H H H H H B H H H H D B B H H D -8 D8Mit263 37 83.834763 D D H H B H H H B H H H H B H H H H B B H H H H H D H D H H H D D D B D D H B H H H H H H B H H B H H B B H H D -8 D8Mit236 38.1 86.35109 D D H H B H H H B H H H H B H H H H B B H H H H H D H D H H H D D D B D D H B H H H H H H B H H B H H B B H H D -8 D8Mit266 44.5 92.726393 D D H H B H H H B H H H H B H H D H B B H H D H H D H D H B H D D D B D D H B D H H H H H B H H B B H B B H H D -8 D8Mit242 47.9 104.283476 D D H H B H H D B H H H H B H H D H B H H H D H H D H D H B H D D D B D D H B D H H H H H B H H B B H B B H B D -8 D8Mit113 52 111.364945 D D H H H H H D B H H H H B H H H H B H H H D H B D H D H B H D D D B H D B B D H D H H H B H H B B H B B B B D -8 D8Mit360 59 119.245087 D D H H H D H D H H H H H B H H H H B H H H H H B D H D H B H D D D B H D B B D H D H H H B H H B B B B B B H D -8 D8Mit156 74.3 131.419403 D D H H D D H H H H D H H B H H H H B H B D H H B D H D H B H D D D B H D H D D H D H D H H H B B B H D B B H D -9 D9Msw3 2 3 B D H H B D B H D B B H H B D H H D H H H H D D H H H B D B H H H H D H H D H H H B B H D D H H H H H D H H H H -9 D9Mit90 9 32.308039 B D H H H D B H H B B H H H H B H D H H D H H H H D B B D H B H H B D H H D H H H B B B D H D H B H H D H H H B -9 D9Mit227 23 41.298948 H D H H H D B H B B B H H D H B H D H H D H H H H D B B D H B H H B D H H D H H H B B B D B D H B H B D H H H B -9 D9Mit4 29 51.931282 H D H H H D H H B B B H H D H B H D D H D H H H H D B B D H B H H H D H H D H H H B B B D B D H B H B D H H H B -9 D9Mit336 35 65.42567 H D H H H D H H B B H H H D B B H D D H D H H H H H B B D H B H H H D B H H D H H B B B D B D H B H B B D H H B -9 D9Mit263 42 75.487998 H D D H D D H H B H H H H D B B H D D D D H H H D H B B D H B H H H H B H H D H D B H B D B D H B H B B D H H H -9 D9Mit236 43 79.938717 H D D H D D H H B H H H H D B B B D D D D H H H D H B H D H B H H H H B H H D H D B H B D B D H B H B B D H H H -9 D9Mit11 47 86.133451 H D D H D D H H B H H H B D B B B D D D D H H H D H B H H H H H H H H B H H D H D B H B D B D H B H B B D H H H -9 D9Mit274 49 96.298228 H D D H D H H H B H H H H H B H B D D D D H H H D H B H H H H H H H H B H H D H D B H B D B H H B H B B D H H H -9 D9Mit53 57 104.684611 D D D H D H H H B H H H H H B H B D D D D H H H D H B H H D D H H H H H H H D H D B H H D B H H B H B B D H H H -9 D9Mit243 61.8 113.283204 D D D H D H H H B H H H H H B H B D H D D H H H D H B H H D D B H H H H H H H H D B H D D B B H B H B B D H H H -9 D9Mit19 71 120.271886 D D D H D B H H H D H H H H B B B D B D D H D H D B B H B D D B H H H H H H H H D B H D H H B H H H B B D B H H -10 D10Mit28 4 9.133172 H H B H H D H H H B B H B H H H B H B B H D H D B D H B H B H B B H D H D H H B D H H D D B B B H H D D B D B D -10 D10Mit247 7 15.477118 H H B H H D H H H B B H B H H H B H B B H D H D B D H B H B H B B H D H D H H B D H H D D B B B H H D D B D B D -10 D10Msw20 12 20.063835 H H B H H D H H H B B H B H H H B H B B H D H D B D H B H B D B B H D H D H H B D H H D D B B B H H D D B D H D -10 D10Mit3 21 28.871991 H H B H H D H H H B B H B H H H B B H B H D H D H D B B H H D B B D D B D H B B D H B D D B B B H H D D B D H D -10 D10Mit194 29 46.564112 H H B H H D H H H B B H B H H H B B H B H H H D H D H H H H D B B D D B H H D B D H B D D B B H H H D D B D H D -10 D10Mit15 33 66.47519 H H B H H D H H H B B B H H H H B B H B H H H D D D H B H H D H H D D B H H D B D H B D H H H H H D D D B H H D -10 D10Mit186 40 75.143879 H H B H H H D H B B B B H H H H B B D B H H H D D D H B H H D H H D D B H H D B D H B D H H H H B D D D B H H D -10 D10Mit261 47 85.081862 H H B H B H D H B B B B H H H H B B D B H H H D D H H B H H D H H D D B H H D B D H B D H H H H B D D D B H H D -10 D10Mit11 50 91.885359 H H B H B H D H B B B B H H H H H H D B H H H D D H H B H H H H D D D B H H D B D B B D H H H H B D D D B H D D -10 D10Mit70 60 103.53585 H H B B B H D D B B B B H H H H H H D B H D H D D H H B H H H H D D D B H B D B D B B D H H H H B D H D B H H H -10 D10Mit233 62 113.818251 H H H B H H D H B B B B H H B H D H D B H D H D D H H B H H H H D D D B H B D H H B B D H H H H B D H H B H H H -10 D10Mit14 65 118.098314 H H H B H H D H B B B B H H B H D H D B H D H D H H H B H B B H D D D B H B H H H B B D H H H H B D H H B B H H -10 D10Mit297 70 124.484225 H H D B H H D H B B B B H H H H D H D B D D D D H H D B H B B H D H D B H B H H H B B D H H H H B D H B B B H H -11 D11Mit226 1 8.804957 H D B H D H H B B H H D D B H H D H H B H H H B D H H H B B H H D B B H D H B H H H H H H H D D H H B D H B B D -11 D11Mit78 3 17.844333 B D H H D H H H B H H D D B H H D H H B H H H B D H H H B B H H D H H H D H H H H H H H H H D D H H B D D B B D -11 D11Mit82 11 25.961779 B H H H D H H H B B H D D B H H D H H B H H H B H H H H B B H H D H H H D H H H H H H H H H D D H H B D D B B H -11 D11Mit51 18 36.205251 B H H H D H H H B H B D D B H H D H H B H H H B H H H H B B H H D D H H D H D B H D H H H H D D H H B D D H B H -11 D11Mit20 20 44.552712 B H H H D H H D B H B D D B H H H H D B H H H B H D H H B B H H D D H H D H D B H D H H H H D D H H B D D H B H -11 D11Mit86 28 54.003616 B H H H D H H D B H B H D B H H H H D B H H H B H D H H B B H H D D H H D H D B H D H H B H D D H H B D D H B H -11 D11Mit177 36 65.026386 B H H H D H B D B H B H H H H H B H D B H H B B B H H H B D H H H D H H H H D B H D H H B H D D H H H D D H H H -11 D11Mit30 40 69.607574 B H H H D H B D B H B H H H H H B H D B H H B B B H H H B D H H H D H H B H D B H D H H B H D D H H H D D H H H -11 D11Mit90 42 70.313263 B H H H D H B D B H B H H H H H B H D B H H B B B H H H B D H H H D H H B H D B H D H H B H D D H H H D D H H H -11 D11Mit195 47 84.653999 B H H H D H B D B H B H H H H H H H D B H H B B H H H H B D H H H D H H B H D B H D H H B H D H H H H D D H H H -11 D11Mit179 52 89.696612 B H D H D H B D B H B H H H H H B H D B H H B B H H H H B D B H H D H H B H D B H D D H B B D H H H H D D H H H -11 D11Mit263 55 95.602952 B H D H D D B D B H B H H H H H B B D B H H B B H H H H B D B H H D H H B H D B H D D H B B D H H D H D D B H H -11 D11Mit67 56 96.86818 B H D H D D B D B H B H H H H H B B D H H H B B H H H H B D B H H D H H B H D B H D D H B B D H H D H D D H H H -11 D11Mit199 62 101.749081 B H D H D D B D B D B H H H H H B B D H H H B B H H H H B D B H H D H H B H D B H D D H B B D H H D H D D H H H -11 D11Mit58 65 104.43775 B H D H D D B D B D B H H H H H B B D H H H B B H H H H B D B D H D H H B H D B H D D H B B D H H D H D D B H H -11 D11Mit181 66.5 109.189663 B H D H D D B D H D B H H H H H B B D H H B B B H H H H B D B D H D H H B H D B B D D H B B D H H D H D D B H H -11 D11Mit338 74.5 115.323096 H H D H D D B D H D H H H D D D B B D D H H H B H H H H H D B H H D H D B H D B B D D H B B D B H D H D D B H H -11 D11Mit48 77 117.993077 H H D H D D B D H D H H H D D D B B D D H H H B H H H H H D B H H D H D B H D B B D D H B B D B H D H D H B H H -12 D12Mit182 2 10.877408 H B H B H H H D H H B B H H H H H H H H H H B D H H H H H H D H H H B H B B H D H H D H H H B D H H B H B D D H -12 D12Mit219 7 27.125818 B B H B H H H D D H B B H H H D H H H H H H B D H H H H H H D H H H B H B B H D H H D H D H B D H H B H B D D H -12 D12Mit153 15 35.920168 H B H B H H H H D H B B H H H D H H H H H H B D H H H H H H D H H D B H B B H D H H D H D H B D H H B H B D D H -12 D12Mit2 19 42.747378 H B H H H H H H D H B B H H H D H H H H H H B D H H H H H H D H H D B H B B H D H H D H D H B D H H B B B D D D -12 D12Mit285 23 55.750111 B H H H B H H H D H B B H H H D H H H H H H B D H H H H H H D H H H B H B B H D H H D H D H B D H H B B B D B D -12 D12Mit36 23.5 61.756235 B H H H B H H H D H B B H H H D H H H H H H B D H H H H H H D H H H B H B B H D H H D H D H B D H H B B B H B D -12 D12Mit114 24.5 71.186214 B H H H B H D H D H H H H H H D H H H H H H B D H H H H H H D H H H B H B B H D H H D H D H B D B H B B B H B D -12 D12Mit158 38 83.720002 B H H H B H D H D H H H H H H D H H H B H H B D H H H H H H B H H H H H B B H D D H H H D H B H B H B B B H B D -12 D12Mit239 44 89.807378 B H H H B H D H D H H H H H H D H H H H H H B D H H H H H H B H H H H H B B H D D H H H D H B H B H B B B H B D -12 D12Mit259 45 93.085023 B H H H B H D H D H H D H H H D H H B H H H B D H H H H H H B B B H H H B B H D D H H H D H B H B H B B B H B D -12 D12Mit231 48 101.804025 B H H H B B D H D H H D H H D D H B B H H H B D H H D H H H B B B H H H B B H D D D H H D H B H B H B B B H B D -12 D12Mit133 56 111.536236 B H H H B B H H D H H D H H H D H B B H B H B H H D D H B H B H B H H B B B H D D D H H D H B B B H B B B H B D -12 D12Mit280 55 112.417854 B H H H B B H H D H H D H H H D H B B H B H B H H D D H B H B H B H H B B B H D D D H H D H B B B H B B B H B D -13 D13Mit57 9 17.085793 D B B B H B D B H D H B B D H B B H B H D H D H H D D D H H H B H H B B D D D H H H H B D H H H H H D H D H H H -13 D13Mit17 10 21.385134 D B B B H B D B H D H B B D H B B H B H D B D H H D D D H H H B H D B B D D D H H H H B D H H H H H D H D H H H -13 D13Mit60 16.1 35.968793 D B B B H B D B H D H B B D H B B H B H D B D H H D D D D H B B H H H B H D D H B H H H D H H H H H D H D H H D -13 D13Mit91 30 46.91822 D B H B H B D B H D H B H D H B B H B H D B D H H H D D D D B B H H H B D D D H B H H H D H H H D H D H D H H D -13 D13Mit13 35 56.582796 D B H B H B H H H D H B D D H B B H B H D B D D B H D D D D B B H H H B D H D H B H H H D H H H D H D H D H H D -13 D13Mit253 37 64.10121 D B H B H B H H H D H B D D H B B H B H D B D D H H H D D D B H H H H B H H D H B H H H D H H H D H D H D H H D -13 D13Mit254 40 76.121928 H B H B H B H H H D H B D D H B B H B H D B H D H H H D D D B B H H H B H H D H B H H H D H D H D D D H D H H D -13 D13Mit126 41 85.473356 H B H B H B H H H D H H D D H B B H B H D B H D H H H D D D B B H H H B H H D H B H B H D H D H D D D H D B B D -13 D13Mit193 43 91.92066 H B H B H B H H H D H H D H H B B H B H D B H D H H H D D D B B H H H B H H D H B H B H D H D H D D D H D B B D -13 D13MIt30 52 102.222838 H B H B H B H H H D H H D H H B B H B H D B H D H B H D D D B B H H H B H H D B B H B H D H D H D D H H D H B D -13 D13Mit148 59.5 109.618962 H B H B D B B H H D H H D H H B B H H H D B H D H B H D D H B B H H D H H H D B B H B D H H D H D D B H D H H D -13 D13Mit262 68 113.604437 H B H B D B B H H D H H D H H B B D H H D B H D H B H D D H H B H H D H H H D B B H B D B H D H D D B H D H H D -13 D13Mit35 75 120.12845 H H H B D B B H H D H H D H H B B D H H H B H D B B H D D H D B H H D H H H D B B H B D B H D H D D B H D H H D -14 D14Mit110 4 8.991951 H H H D B B H H H B D B H H H D B H D H H H B D B H H B B B H H D H H H H B D D H D D B H D B B B B B H D H D B -14 D14Mit98 4 17.356224 H B H D B B H H H B D B H H H D B H D H H H B D B H H B B B H H D H H H H B D D H D D B H D B B B B B H D H D B -14 D14Mit206 5 21.523025 H D H D B B H H H B D B H H H D B H D H H H B H B H H B B B H H D H H H H B D D H D D B H H B B B B B H D H D B -14 D14Mit54 12.5 36.137025 D D H D B H B H H B H B H H H D B H B H H H B H H B H B B B H H H H B H D B D D H D D B H H H B B B H H D H D B -14 D14Mit212 13 40.817103 D D H D B H B H D B H B B H H D B H B H H H B H H H H B B B H H H H B H D B D D H D D B H H H B B B H H D H D B -14 D14Mit142 19.4 54.812402 D D H D B H B H D B H B B H H D B H B H B D B H H H H B B B H H H H B H H B D H H H D B H H H H B H H H H H D B -14 D14Mit234 22.5 60.262795 D D H D B H H H D B H B B H H D B H B H B D B H H H H B B B H H H H H H H B D H H H D B H H H H B H H H H H D B -14 D14Mit262 28.5 67.704456 D D H D B H H H D B H B H H H D B H B H B D B H H H H B B B H H H H H H H B D H D H D B H H H H B H H H H H D B -14 D14Mit115 40 73.244747 H D H D B H H H D B H B H H B D B H B D B D B H H H B B B B H H H H H H H H D H D H D B H H H H B H H H H H D B -14 D14MIt35 43 79.559826 H D H D B H H H D B H B H H B D B H B D B D B H H H B B B B H H D H H H H H D H D H D B H H H H B H D H H H D B -14 D14Mit263 44 89.3607 H D H D B H H H D H H B H H B D B H B D B H B H H H B B B B H B D H B H H H D H D H D B H H H H B H D H H H D B -14 D14Mit228 46.7 99.784302 H D H D B H H B D H H B H H B D B H B D B H B H D H B B B B H B D H B H D H D H D H D B H H H H B H D H H H H B -14 D14Mit165 52.5 106.982673 H D H D B H H B D H B B H B B D B H B D B H B H D H B B B H H B D H B H D D D H D H H B H H H H B H D H H H H B -14 D14Mit185 54 117.296055 H D H H B B H B D H B B H B B D B H B D B H B H D H H H B H H B D H B H D D D H D H H B H H H H H H D B H H H B -14 D14Mit266 59 121.431466 H H H H B B H B D H B B H H B D H H H D B H H H D H H H B H H B D H B H D D D H D H H B D B H D H H D B H H H B -15 D15Mit12 6.4 3.160684 B H B B H H H H H D B H H H B D B B B B B D B B H D H D H H B H D D B D D B H D D H H D B B B B H H D H D H B B -15 D15Mit53 9.2 13.210209 H H B B H H H H H D B H H H B D B B B B H D B B H D H D H H B H H D B D D B H D H H H H B B B B H H D H D H B B -15 D15Mit252 13.2 22.550162 H H B B H H H H H D B H H H B D B B B B H H B B H D B D H H B H H D H D D H H D H H H H B B B B H H D H D H B B -15 D15Mit7 14.5 32.946234 H H B B H H H H H D B H H H B D B B B B H H B B H D B D H H B H H H H D D H H H H H H H B B B B H H D H D D B B -15 D15Mit8 14.6 33.392974 H H B B H H H H H D B H H H B D B B B B H H B B H D B D H H B H H H H D D H H H H H H H B B B B H H D H D D B B -15 D15Mit5 22.2 43.279929 H H B B H H H H H D B B H D B D B B B H H H B H H D B D H H B H H H H D D H H H H H H H B B B B H H D H D D B B -15 D15Mit232 24 52.944064 H H B B H H H H H H B B H D B D B B B H H H B H H D B D H H B H H H H D D H H H H H H H H B B H H H D H D D H B -15 D15Mit270 29 63.349351 H H H B H H H H H H B B H D B D B B B H H H B H H D B D H H B H H H H D D H B H B H H H H B B H H H D H H D H B -15 D15Mit90 36 68.969215 H B H H B H H H H H H B H D B D B B B H H H B H H D B D H H B H H H H D D H B H B H H H H B B H B H D B B D H H -15 D15Mit239 45 78.407334 H B H H H H H H H H H B H D B D B H B D H H H H H D B D H H B H H H H D D H B H B B H H H B B H B H D H B D H D -15 D15Mit72 51.1 84.545798 H B H H B H H H H H H B H D B D B H B D H H H H H D B D H H B D H H H D D H B H B B H H H B B H H H D H B D H D -15 D15Mit34 52.5 90.583805 H B H H B H H H H H D B H D B D B H B D H H H H D D B D H H B D B H H D D H B H B B H H H B H H H H D H B D H D -15 D15Mit272 57.5 94.239432 H B H D B H H H B H D B H D H H B H B D H H H H D D B D H H B D B H H D D H B H B B H H H H H H H H D H B D D D -15 D15Mit42 59.2 98.887015 H B D D B H H H H H D B H D D H D H B D H H H H D D B D H H B D B H H D D H B H B B B H D H H H H D D H B D D D -15 D15Mit15 62 102.823544 H B D D B H H H H H D B H D D H D H B D H H H H D D B D H H B D B H H D H H B H B B B H D H H H H D D H B D D D -15 D15Mit35 62 103.347763 H B D D B H H H H H D B H D D H D H B D H H H H D D B D H H B D B H H D H H B H B B B H D H H H H D D H B D D D -16 D16Mit182 3.1 5.682588 H H H B H H H B H H D H H H B H B H H H D B D D B B B H H H H B B B H H D H B D B H B H D D B B H B H H B H H H -16 D16Mit100 8.5 12.095264 D H H B H H H B H H D H H H B H B H H H D B H D B B B H H H H H B B H H D H B D H H B D D D B B H B H H B H H H -16 D16Mit88 9.7 13.249056 D H H B H H D B H H D H H H B H B H H H D B H D B B B H H H H H B B H H D H B D H H B D D D B B H H H H B H H H -16 D16Mit101 17 23.737061 D B H B H H D B H H D H H H B H B H H B D B H D B B B H H H H H B B H D D H B D H H B D H D B B H H H H B H H H -16 D16Mit58 23.3 32.312107 D B H H H H D B H H H H B H B H B H H B D B H D B H B H H H H H B B H D D H H D H H B D H D B B H H H H D H H H -16 D16Mit84 34.2 45.39781 D B H H H H D B B H H H B D B H H H H H D B B D B H B H H H H H B B H D D H H D H B B D H H H B H H D H D H H H -16 D16Mit5 38 57.773676 D B H H H H D B B H H H B D B H H H H H D B B D B H B D H H H H H B H D D H H D H B B D H H H B D H D H D H H H -16 D16Mit139 43 65.669761 D B H H H H H H B H H H B D B H H H H H H B B D B H B D H D H H D B H D D H H D H B B D H H H B D H D H D H H H -16 D16Mit217 45.5 77.361452 D B H H H H H H B H H H B D B H H H H H H H B D B H B D H D H H D H H D D D D D H B H D H H H B D H D H D H D H -16 D16Mit152 57 85.804078 D B H H H H H H B H H H H D B H H H H H H H B D B H B D H D H H D H H D D D D D H B H D H H H B D H D H D H D H -16 D16Mit106 68 98.051756 H B D H H H H H H D H D H D B B H D D H B B B H H H H D H D D H D H H D H D D D H B H D H H D B D H D H D D D H -17 D17Mit267 2 3.354861 B D D H D D B D H H D H B H B H H H H D D D B D H B D D H B B H D H H B H D B B D B H H D H B H H H H D D D D H -17 D17Mit213 9.33 16.752156 B D D H D D B D H D D H B H H H H H H D D D H D H B D D H B B H D H H B H D B B D H H H D H B B H H H D D D D H -17 D17Mit100 11.8 26.318982 B D D H D D B D H D D H B H H H H H H D D D H D H B D D H B B H D H H B H D B B D H H H D H B B H H H D D D D H -17 D17Mit175 17.7 31.979622 H D D D D D B D H D H D H H H H H H H D D D H D H H H D D B B H D H H B H D B H D H H H D H B B H H H D H D H H -17 D17Mit21 18.6 34.380178 H D D D D D B D H D H D H H H H H H H D D D H D H H H D D B B H D H H B H D B H D H H H D H B B H H H D H D H H -17 D17Mit24 20.4 37.619108 H D D D D D B D H D H D H H H H H H H D D D H D H H H D D B B H D H H B H D B H D H H H D H B B H H H D H D H H -17 D17Mit10 24 47.672121 H D D D D D B D B D H D H H H H H H H D D D H H H H H D D H B H H H H B H D B B D H H H D B B B H H H D H D B H -17 D17Mit20 34.3 57.366869 H D D D D H B H B D H D H H H H H H H D D H H B H H H D D H B B H H H B H D B B D H H D D B B B H H H H H H B H -17 D17Mit89 36 63.988383 H D D D D H B H B D H D H H H H H H H D D H H B H H H D D H B B H H H B H D B B D H H D D B B B H H H H H H B H -17 D17Mit152 37.7 65.689823 H D D D D H B H B D H D H H H H H H H D D H H B H H H D D H B B H H H B H D B B D H H D D B B B H H H H H H B H -17 D17Mit39 45 74.681455 H H D D H H B H B D H D D H H H H H H D D H H B H H B B D H B B H H B B H D H B D H D D D H H H H H H H H H B H -17 D17Mit41 53 84.734942 H H D D H H B H B D H D D H D H D H H D D H D B D H B B D H H H H H B B H H H B H H D D D H H H D H H H H H B H -17 D17Mit221 56.7 90.487044 H H D H H H B H H D H D D H D H D H H D D B D B D H B B D H H H B H B B H H H B H H D D H H H H D H H B D H B H -17 D17Mit244 55.7 91.253863 H H D H B H B H B D H D D H D H D H H D H B D B D H B B D H H H B H B B H B H B H H D D H H H H D B H B D H B H -18 D18Mit19 1 5.041116 B B B B H B H H B H B D D D B H H H B D D H B D H B H H D B H B D B B D B D H D H H H D H D H H D B H H H H B H -18 D18Msw9 3 9.164794 B B B B H B H H B H B D D D B H H H B D D H B D H B H H D B H B D B B D H D H D H H H D H D H H D B H H H H H H -18 D18Msw17 10 17.128182 B B B B H B H H H B B D D D B H H H H D H H B D H B H H D B H B D B B D B D H D H B H D H H H H D B H H H H B H -18 D18Mit68 11 21.594125 B B B B H B H H H B B D D D B H H H H D H H B D H B H H D H H B D B B D B D H D H B H D H H H H D B H H H H B D -18 D18Mit111 11 21.671805 B B B B H B H H H B B D D D B H H H H D H H B D H B H H D H H B D B B D B D H D H B H D H H H H D B H H H H B D -18 D18Mit225 16 30.775424 H B H B H H H H H H B H D D B H H H H H H H B D H B H H D H H B H B B D B D H D H B H D H H H H D B B H H H B D -18 D18Mit17 22 39.646514 H B H B H H H H H H B H D D B H H H H H H H B H H B H H D D H B H B B D B D H D H B H D B H H H D B B H H H B D -18 D18Mit53 27 52.992737 H B H B H H H H H H B B D D B H H H H H H H B H H H H H D D H B H B H D B D D D H B H H B H H H D B B H H H B D -18 D18Mit55 25 53.317603 H B H B H H H H H H B B D D B H H H H H H H B H H H H H D D H B H B H D B D D D H B H H B H H H D B B H H H B D -18 D18Mit184 41 66.978896 H B H B H H B H H H B B D D H H B B H H H H B B H H H H D D H B H B H D B D D D H B H H H H H H D B H B H H B D -18 D18Mit79 47 75.969567 H B H B H H B H H H B B D D H H B H B H B H B B H D D H D D B B H B H D B D D D D B H H H H H D D B H B H H B D -18 D18Mit7 49 77.086364 H B D B H H B H H H B B D D H H B H B H B H B B H D D H D D H B H B H H B D D H D B H H H H H D D B H B H H B D -18 D18Mit213 55 84.78992 H B D B H H B H H H H B D H H H B H B H B H B B H D D B D D H B B B D B B D D H D B H H H H H H D B H B D B B D -19 D19Mit109 3 6.207606 H H B H H H H H H H H D D B B D B H B H B H D B H H H H H H H D D H H D B B H D H H H H H H H H H H H H D B H B -19 D19Mit42 5 10.157494 H H B H H H H H H H H D D B B D B H B H B H D B H H H H H H H D D H H D B H H D H H H H H H H H H H H H D B H H -19 D19Mit85 12 18.60417 D H B H H B H H H H H D D B B D B B B H B H D B H H D H H H H D D H H H B H B D D D B H H H D H H B H H H B H D -19 D19Mit16 15 20.420341 D H B H H B H H H H H D D B B D B B B H B H D B H H D H H H H D D H H H B H B D D D B H H H D H H B H H H B H D -19 D19Mit13 20 32.713512 D H B B H B H B H H H H D B B D B B B H B H D B B H D D H B H D D H D B B H B D D D B H H H D D H B H H H D H D -19 D19Mit89 41 42.573794 D H B B H B H B B H H H H B H D B B B H B H D B H H D D H B H D D H D B B H B D D D B H H H D D H H H H H D H D -19 D19Mit38 47 47.260672 D H B B H B H H B H H H H B H D B B B H B H D B H H D H H B H D D H D B B H B D D D B H H H D D H H H H H D H D -19 D19Mit103 52 53.838655 D D H B H B H H H H H H H H H D B B B H B H D B H H D H H B H H D H D B B H B D D D B H H H D D H H H H D D H D -19 D19Mit55 52.8 55.379504 D D D B H B H H H H H H H H D D B B B H B H D B H D D H H B H H D H D B B H B D D D B H H H D D H H H H D D H D -19 D19Mit137 54 59.209811 D D D B H B D H H H H H H H D D B B B H H B D B H D H H H H H H D H D B B H B D D D B H H H D D H H H H D D H D -X DXMit89 3 9.977111 D H B D H D D B D D B D D B D B H D H B D B B D D B D B D D D D H B D B H H B B D B H B B D H B B B B B D D D D -X DXMit166 15.5 49.036674 D H B D H D D H D D B D D B D B H H H D D B B D D B D D D D D D H B D B H H B B D D H B B D H B B D B B D B D D -X DXMit143 26 69.642046 D H B D H D D D D D B D D B D D H H H D D B B D D B D D B D D D B B H B H D B B D D H B B D H B B D B B D B H D -X DXMit1 29 70.273782 D H B D H D D H D D B D D B D D H H H D D B B D D D D D B D D D B B H B H D B B D D H B B D H B B D B B D B H D -X DXMit117 50.8 127.822561 D H B H D D D H D D B D D B D D H H H D D B B D B D D B B D H D B B H B H D B B D D D D B D H B B D D B B B H D -X DXMsw125 52 140.351087 D H D H D D D H D D B D D B D D H H H D D B D D B D D B B D D D B B H B B D B B D D D D B H H B D D D B B B H H -X DXMit186 69 161.804093 D H D H D D D H D D B D D B D D H H H D D B D D B D D B B D D D B B H B B H B B D D D D B H H B D D D B B B D H +#this is B6D2F2 genotype file, it should be tab-delimited +#the first three/four columns should be "Chr, Locus, cM, [Mb]" (case sensitive) +#please save as Unix format text file. +#comment line always start with a '#' +#type riset or intercross +@type:intercross +@name:B6D2F2 +#abbreviation of maternal or paternal parents +@mat:B +@pat:D +#heterozygous , optional, default is "H" +@het:H +#Unknown , optional, default is "U" +@unk:U +Chr Locus cM Mb CASE001 CASE002 CASE003 CASE004 CASE005 CASE006 CASE007 CASE008 CASE009 CASE010 CASE011 CASE012 CASE013 CASE014 CASE015 CASE016 CASE019 CASE020 CASE021 CASE022 CASE023 CASE024 CASE025 CASE027 CASE028 CASE030 CASE031 CASE032 CASE033 CASE034 CASE035 CASE036 CASE037 CASE038 CASE039 CASE040 CASE041 CASE042 CASE043 CASE044 CASE046 CASE047 CASE048 CASE050 CASE051 CASE052 CASE053 CASE054 CASE055 CASE056 CASE057 CASE058 CASE059 CASE060 CASE062 CASE063 +#Y DYCTC3.3411 1 0.891414 B F B F F F B F B F F B D B F B F F F B F B D B D B F B D D F B F B F F F F B F B B F B B F F B D B B B B B F F +#Y DYCTC8.8315 3 3.360446 B F B F F F B F B F F B D B F B F F F B F B D B D B F B D D F B F B F F F F B F B B F B B F F B D B B B B B F F +#M UT-M-9461 0 0.009462 B B B B B B B D B B D B D B B B D B D B B B D B D B B B D D B B D B B D D B B D B B B B B B B B D B B B B B B B +1 D1Mit118 8.3 3.959096 B H H H H H B B H B B H H B D D H H H H B B B D H H D D H H H H H B H B D B B B H B H H D D D H B D B H H H H H +1 D1Mit430 10 14.271355 B H H H H H B B H B H H H B D D H H H H B B B D H H D D H H H H D B H B D H B H H H B H D D D H B D B H H H H H +1 D1Mit373 17 26.535325 B H H D H H B B H B H H H H D D H H H H B B H D H D H D H H H H D H H H D H B H H H B H D D D H B D B H H H H H +1 D1Mit171 20.2 36.800666 B H H D H D H H H B H H H H D D B H H H B B H D H D H D D H H H D H H H D H B H H H B H D D D H B D B H H H H H +1 D1Mit236 25.7 45.435457 B H H D H D H H D B H B H H D D B H H H B H H D H D H D D H H H D H H H H H H H H H H H D D D H B B B H H H H H +1 D1Mit214 32.1 58.290808 B D H D D H H H D B H B H H H D B H H H B H H D H D H D D H H H D H H H H H H H H H H H D D D H B B H H H H H H +1 D1Mit300 32.8 63.927416 B D H D D H H H D B H B H H H D B H H H B H B D H D H D D H H H D H H H H H H H H H H H D D D H B B H H H H H H +1 D1Mit282 36.7 73.273628 B D H D D H H H D B H B H H H D B H H H B H H D H D H D D H H H D H D H H H H H H H H H H D D H B B H H D H H H +1 D1Mit80 53 88.274502 B D H H D H H H D H D B H H H D B B H H B H H D H D B D H H H B D H D H H D H H H H H H H D D H H B H H D H H H +1 D1Mit48 54 90.464814 B D H H D H H H D H D B H H H D B B H H B H H D H D B D H H H B D H D H H D H H H H H H H D D H H B H H D H H H +1 D1Mit45 58.5 94.909763 H D H H H H H H D H D B H H H D B B H H B H H D H D B D B H H B D H D H H D H H H H H H H D D H H B H H D H H H +1 D1Mit135 61 107.206162 H D H H H H H H D H D B H H H D B B H H B H H D H D B D B H H B D H D H B D H H H H H H H D D H H B H B D H H H +1 D1Mit387 62 117.229212 H D H H H H H H D H D B H H H D B B H H B H H D H H B D B H H B D H D H B D H H H H H H H D D H H B H B D H H H +1 D1Mit91 64 128.355209 H D H H H H H H D H D B H H B D B B H H B H H D H H B D B H H B D H D H B D H H H H H H H D H H H B H B D H H H +1 D1Mit103 73 137.882255 H D H H H H H H H H D B H H B D B B H H B H H D H H B D B D H B D H D H B D H H H H H H H D H H H B H B D H H H +1 D1Mit265 74.3 150.686863 H D H H H H H H H D D B H H B D B B H H B H D D B H B H B D H B D H D H B D H H H H H H H D H H H B H B D H H H +1 D1Mit14 74.5 158.704597 H D H H H H H H H D D B H H B D B B D H B H D D B H B B B D H B D H D H B D H H H H H H H D H H H B H B D H H H +1 D1Mit57 87.8 168.634127 H D H H H H H H H D D B H H B D B B D H H H D D B H B B B D H H D H D H B D H H H H H H H D H H H B H B D H H H +1 D1Mit113 93.2 173.73461 H D H H B H H H H D D B H H B H B B D H H H D D B B B B H D H D D H H H B D B H H H H H H D H H H B H B D H H H +1 D1Mit206 95.8 174.934328 H D H H B D H H H D D B H H B H B B D H H H D D B B B B H D H D D H H H B D B H H H H H H D H H H B H B D H H H +1 D1Mit426 101 182.341751 H D H H B D H D H D D B H H B H B B H H H H D D B B B B H D H D H H H H B D B D H D H H H D H H D B H B D H H H +1 D1Mit155 112 196.255162 H D B H B D H D H D H D H H B B H B H H H H D D B B B B H D H D H D H H H D B D H H H D H H H H D B H H D B B H +2 D2Mit1 1 3.80336 B D H H B H B H B H H H D H B H H B B H H H D H H H D B H B H H D H H H B B D H H H H H D B H D D D H B D H H B +2 D2Mit464 10.9 18.517336 B D H H B H H H B H B H D H H H B B B H H H D H H H D B H B H H D D H H B B D D D H H H D H H H D H H B D H H H +2 D2Mit6 12 20.814593 B D H H B H H H B H B H D H H H B B B H H H D H H H D B H B H H D D H H B B D D D H H H D H H H D H H B D H H H +2 D2Mit80 12 20.928231 B D H H B H H H B H B H D H H H B B B H H H D H H H D B H B H H D D H H B B D D D H H H D H H H D H H B D H H H +2 D2Mit235 22.5 32.753979 B D H D B H H D B H B D D D H H B B B H H H D H H D D B H B H H D D H H B B D D D H H H D H H H D H H B D H H D +2 D2Mit238 28 33.976569 B D H D B H H D B H B D D D H H B B B H H H D H H D D B H B H H D D H H B B D D D H H H D H H H D H H B D H H D +2 D2Mit237 30 40.851 B D H D B H H D B H B D H D D H B B B H H H D H H D D B H B H H D D H H B B D D D H H H D H H H D H H B D H H D +2 D2Mit458 31.7 50.709674 B D H D B H H D H H B D H D D H B B B H H H D D H D D B H B H H D D H H B B D D D H H H D D D B D H H B D H H D +2 D2Mit61 36 60.528324 B D H D B H H H H H B D H D D B B B B D H H H D H D H B H H H H D D H H B H D D D H H B D D D B D B B B D B H D +2 D2MIt37 45 74.531829 B D H D B H H H D H B D H D D D H B H D H H B D H H B B H H H H H D H B B H D H H H H B D D D B D B B B D B H H +2 D2Mit66 47.5 84.657699 H D H D B H D H D H B H H D D D H B H D H H B D H H B B H H H H B D H B H H D H H H H B D D D B D B B B D H H H +2 D2Mit45 53 91.783197 H D H D B H D H D H B H H H D H H B H D H H B D H H B B H H D H B D H B H H D H H H H B D D D B D B B B D H H H +2 D2Mit12 53 102.941478 H D H D B H D H D D H H H H D H H B H D H H B D H H B B H H D H B D H B H H D B H H B B D D D B D B B B D H H H +2 D2Mit58 53.4 108.099785 H D H D B H D H D D H H H H D H H B H D D H B D H H B B H H D H B D H B H H D B H H B B D D D B D B B B D H H H +2 D2Mit484 55 118.399165 H D H D B H D H D D H H H H D H H B H D D B B D B H B B H D D H B D H B H H H B H H B B D D D B H B B H D H D H +2 D2Mit164 69.5 123.215788 H D H D B H D H D D H H H H D H H B H D D B B D B H B B H D D H B D H B H H H B H H B B D D D B H B B H D H D H +2 D2Mit223 71 134.813146 H D H H B B D H D D H H H H D H H B H D D B B D H H B B H D D H B H H B H H H B H D B B D D D B H B B H D H H B +2 D2Mit403 72 144.499676 H D H H B B D H D H H H H H D H H B H D D B B D H H B B H D D H B H H B H H H B H D B B D D D B B B B H D H H H +2 D2Mit286 74 154.338344 H H H B B B H H D H H H H H D H H B H D D B B D H H B B H D D H B H H B H H H B H D B B D D D B B B B H D H H H +2 D2Mit50 80 162.50259 H H H B B B H H D H H H H H D H H B H D D B B D H H B B H D D D B B H B D H B B H H B B D D D B B H H H H H H B +2 D2Mit311 83.1 165.648472 H H H B B B H H D H H H H H D H H B H D D B B D H H B B H D H D B H H B D H B B D D B B D D D B B D H H H H H B +2 D2Mit148 105 178.535249 H H B B B B H B H H H B H H D H H H H D H B B D H D H B H D H D H H H B H H B H D D H B D D H B B D H H H H H B +3 D3Mit221 2.4 7.891492 H H H H B D H H B D H D H H H D H D D H D H B B H H H B H B H H H D H B H H H D H D B B B H D H B H B B H H D H +3 D3Mit62 4.6 17.467422 D H H D B D H H B D H D H H H D H H D H D H B B H H H B H B H H H D B B H B H D H D B B B H D B B H B H H H H H +3 D3Mit305 11.2 27.097878 D H H D B H H H B D B D H H H D H H D H D H B B H H H B H B H H H D H B H B H D H D B B B H D B H H B H H H H H +3 D3Mit151 18.5 31.137264 D H H D B H H H B D B D H H H D H H D H D H B B H H H B H B H H H D H B H B H D H D B B B H D B H H B H H H H H +3 D3Mit63 21.5 40.846321 D H H D B H H H B H B D H H H H H H D H D H B H H H H B H B H H H H H B H B H H H D B B H H D B H H B D H B H H +3 D3Mit65 23.3 50.488799 D H H D B H H H B H B D H H H H H H D H D H B H H H H B H B H H D H H B B B H H H D B B H H D B H H B D H B H H +3 D3Mit185 29.5 57.246564 D H H D B H H D B H B D H H B H H H D H D H H H B D H B H B D H D H H H B B H H H D B B D H D B H H H D H B H H +3 D3Mit154 33 68.61339 D H H D B H H D B H B H H B B H H H D H D H D H B D B B H B H H D H D H B H H H H D B B D H D B H H H D B B H H +3 D3Mit51 35.2 76.80336 D H H D B H H D H H B H H B B H H D D H D H D H B D B B H B H H D H D H B H H H H D B B D H D B H H H D B B H H +3 D3Mit187 42.4 87.067071 D H H D B H H D H H B H H B B H H D D H D H D H B D B B H B H H D H D H B H H H H D B B D H D B H H H D B B H D +3 D3Mit156 45.2 92.359916 D H H D B H H H H H B H H B B H H D D H D D D H B D B B H B H H D H D H B H H H H D B B D H D B H H H D B B H D +3 D3Mit76 45.2 94.832825 D H H D B H H H H H B H H B B H H D D H D D D H B D B B H B H H D H D H B H H H H D B B D H D B H H H D B B H D +3 D3Mit189 50 100.779518 D H H D B H H H H H B H H B B H D D D H D D D H B D B B H B H H D H D H B H H H H D B B D H D B H H H D B B D D +3 D3Mit78 55 111.166674 D H H D B B H H H H B H H B B H D D D B D D D H B D B B H B H H H B D H B H H H H D B B H H D B H H H D B B D D +3 D3Mit43 58.8 121.164708 D H H H B B H H H H H H H B B H D D D H H D D H B D B B H B H H H B D H B H H H H D B H H H D H H D H D B B D D +3 D3Mit14 65 131.693819 D H H H B B H H H H H H H B B H D D D H H D D H B D B B D B H H H B D H B H H H H D B H H D D B H D H D B B D D +3 D3Mit17 71.8 143.310188 D H H H B B H B H D H H H B B H H D D H H D D H B D B B D B H H H B D H H H H H H H H H H D D B D D H D B B H D +3 D3Mit147 79.4 148.408372 D H H H H B H B H D H H H B B H H D D H B D D H B D H B D B H H H B D H H H D H H H H H H D D B D D H D B B H D +3 D3Mit89 87.7 156.500068 D H D H H B D B B D H H H B B H H D H H B D D H H D H B D B H H H B D H H H D H H H H H H D H B D D H H B B H D +3 D3Mit19 87.7 157.646003 D H H H H B D B B D H H H B B H H D H H B D D H H D H B D B H H B B D H H H D H H H H H H D H B D D H H B B H D +4 D4Mit149 0 3.58427 H H B H D B H B B B D B H D B B B D H H B B B H H H B H H H H B H H H B B H H H B D H H H H D B D H H D H B B B +4 D4Mit101 3.2 9.629759 H H B H D B H B B B D B H D B B B D H H B B B H H H B H H H B H H H H B B D H H B D H H H H D B D H H D D B B B +4 D4Mit171 6 22.41343 H B H H D B H B B B D B H D B B B H H H B B B H H H B H H H B H H H H B B H H H B D H H H H H B D H H D D B B B +4 D4Mit192 6.3 31.064208 H B H H D B H B B B D B H D B B B H H H B H B H H H B H H H B H H B H B B H H H B D H H H H H B D H H D D B B B +4 D4Mit172 10 34.342408 H B H H H B H B B B D B H D B B B H H H B H D H H H B H H H B H H B H B B H D H B D H H H H H B D H H D D B B B +4 D4Mit214 17.9 45.671313 H B H H H H H H B B D B H D B B B H H H H H D H D H H D H H B H H B H B B H D H B D D H H H H B D H H D D B B B +4 D4Mit111 21.9 53.56371 H B H H H H H H B B D B H D B B B H H H H H D B D D H D H H B H H B H B B H D H B D D H H H H B D D H D D B B B +4 D4Mit178 35.5 66.843058 D B H H H H D H D B D B H D B B B H B H H H D B D H H D D D B H H B H B B H D H H D D H H H H B D D H D D B B B +4 D4Mit142 37.5 73.86524 D B H H H H D D D B D B H D B B B H B H H H D B D H H D D D B H D B H B B H D H H D D H H D H B D D B D D B B H +4 D4Mit297 38 80.923505 D B H H H H D D D B D B H D B B B H B H H D D B D H H D D D B H D B H B B H D H H D D D B D B B D D B D D B B H +4 D4Mit186 44 90.81234 D B H H H H D D D B D H D D B B B H B H H D D B D H H D D D B H D B H B B H D H D D D D B D B B D D B D H B B H +4 D4Mit255 48.5 98.887399 H H H H H H D D D B H H D D B B B B B H H D D B D H H D D D B H D B B B B H D H D H D D B D B B D D B D H H B H +4 D4Mit146 53.6 109.473539 H H H H H H D D D H H H D H B B B B B H H D D B D H H D D D B H D B B B B H D H D H D D B D B B D D B D H H D H +4 D4Mit332 53.6 114.164598 H H H H H H D D D H H H D H B B B B B H H D D B D H H D D D B H D B B B B H D H D H D H B D B B D D B D H H D H +4 D4Mit37 56.5 116.887378 H H H H H H D D D H H H D H B B B B B D H D H B H H H D D D B H D B B B B H D H D H D H B D B B D D B D H H D H +4 D4Mit334 57 119.383705 H H H H H H D D D H H H D H B B B B B D H D H B H H H D D D B H D B B B B H D H D H D H B D B B D D B D H H D H +4 D4Mit203 60 129.249261 H H H H H H D D D H H H D H B B B B B D H D H H H H H D D H B H D H B B B D D H D H D H B D B H D D B D H H D H +4 D3Mit54 4.6 135.130158 H H H D B D H H B D H D H H H D H H D H D H B B H H H B H B H H H D B B H B H D H D B B B H D H B H B H H H D H +4 D4Mit312 69.8 141.449884 H D H H H H H D D H H H D H D B B B B D H D B H H H H D D H B H D H H B B D H H D H D H B D B H D D B H H H D D +4 D4Mit42 81 150.944102 H D H H H H H D H H H H D H D B B B B D B D B H H H H D D H H B D H H H B D H H D B D H H D B H D D H H H H D D +5 D5Mit346 0.5 4.879512 H H D B D D D H H B D B H H H H H B B H H D B D D D H H H B H H D H H H D D D H B D D D H D H H D H D H B H B H +5 D5Mit294 8 20.863134 H H D B D D D B H B D B H H H H D B B D H D B D H D H H H B H H H H B H H D D H B D D D H D H H D H D H B B B D +5 D5Mit348 8 24.424936 H H D H D D D B H B H B H H H H D B B D H D B D H D H H B B H H H H B H H D D H B D D D H D H H D H D H B B B D +5 D5Mit352 20 35.957615 H H D H D D D B B B H B H H H H D B B D H D B D H D H H B H H H H H B H H D D H H H D D H D H H D H D H H B B D +5 D5Mit267 23 40.977741 H H D H D D D B B H H B H H H H D B B D D D B D H D H H B H H H H H B H H D D H H H D D H D H H D H D H H B B D +5 D5Mit255 30 55.345577 H H D H D D D B B H H B H H H H H H B D D D D D H D H H B H B H H H B H H D D H H H D D H D H H H H D H H B B D +5 D5Mit197 36 65.040326 H H D H D D D B B H H B H H H H H H B D D D D D H H H H B H B H H H B H H D D H H H D D H D H H H H H H H B B D +5 D5Mit356 41 73.587246 D H H H D D D B H H H B H H H H H H H D D H D D B H H H B H B H H H B H H H D D H H D D H D H H H H H H H B B D +5 D5Mit309 44 79.931745 D H H H D D D H H H H B H H H H H H H D D H D D B H H H B H B H H H B H H H D D H H D D H D H H H H H H H B B D +5 D5Mit18 50 93.726234 D H H H D D D H H H H B H H H H H H H D D H D D B H H H B H B H H H B H H H D D H H D D H D H H H H H H H B B D +5 D5Mit403 57 106.233589 D H H H D H H H D H H B H H H H H H D D D H D D B D H H B H B H H H B H H H D D H H D D H D H B B H H B H B B H +5 D5Mit25 59.8 114.3337 D H H H D H H H D H H B H H H H H H D D D H D D B D H H B H B H H H B H H H H D H H H D B D H B B H H B H B B H +5 D5Mit95 68.5 125.309604 D H H H D H H D D H H B B H H B H D D H D H D D B D H D B D B H H H H H H H H D D H H D B D H B B H H B H H B B +5 D5Mit139 69 125.93169 D H H H D H H D D H H B B H H B H D D H D H D D B D H D B D B H H H H H H H H D D H H D B D H B B H H B H H B B +5 D5Mit372 73 132.603108 D D H H D H H D D H H B B H H B H D D H D H D D B D H D B D B D H B H D H H H D D H H B B D H B B H D B H H B B +5 D5Mit222 85 142.979299 D D H H D B H D D H D B B H H B H D D H D H D D H D H D H D B D H B H D H H H D D H H B H D D H B H D H H H B H +5 D5Mit223 89 147.662596 D D H H D B H D D H D B B B H B H D D H D H H D H D H D H D B D H B H D H H H D D H H B H D D H B H D H H H B H +6 D6Mit86 0.5 4.414883 D H H D D B B B H B D H H H H H D H D H B H D D D H H D D B D H H D B D H B D H D H H H H B H D D B B H H H H H +6 D6Mit264 3.2 16.618913 D H H D D B B H H B D H H H H H D H D H H H D D D H H D D B D H H D B H H B D H D H H H H B H D D B B H H H H H +6 D6Mit159 7 29.701221 D H D D D B H H B B H H H H H H D D D H H H D D D H H H D B D H H D B H H B D H H H H H H B H D D H B H H H H H +6 D6Mit268 15.5 34.684662 D H D D D B H H B H H H H H H H D B D H B H D D D H H H D B D H H D B H H B D H H H H H H B H D H H B H H H H H +6 D6Mit207 19 44.415869 H H D D D B H D H H H H H H H H D B D H B H D D D B H H D B D H H H B H H B D H H H H B H B H D H H B D H H H B +6 D6Mit74 20.5 48.676554 H H D D D B H D H H H H H H H H D B D H B H D D D B H H D B D H H H B H H B D H H H H B H B H D H H B D H H H B +6 D6Mit93 26.3 52.111711 H H H H D B H D H H H H H H H H D B D H B H D D H B H H H H D H H H B H H B H H H D H B H B H D H H B H H H H B +6 D6Mit316 28.9 55.505942 H H D D D B H D H H H H H H D H D B D H B H D D D B H H H B D D H H B H H B H H H D H B H B H D H H B H H H H B +6 D6Mit175 29.9 64.944267 H H D D D B H D H H H B H H D H D B D H B H D D D B H H H B D D H H B H H B H H H D H B H B H D H H B H H H H B +6 D6Mit188 32.5 75.397576 H H D D D B H D H H H B H H D H D B D H B H H D D B H H H B D D H H B H H B H H H D H B D B H D H H B H H H B B +6 D6Mit69 35 83.5957 H H H D D H H D H H H B H H D H H B D H B H H D D B B H H B D D H H B H H B H H H D H B D B H D H H H H H D B B +6 D6Mit102 38.5 93.413942 H H H H H H H D H H H B H H D H H B D H B H H D D B B H H B D D D H B H H B H H H D H B D B H D H D H H H D B B +6 D6Mit39 45.5 106.519219 H H H H H H H D H H H H H H D H H B D B B H H D D B B H H H D D D H H H H B H D H D H B D H H D H D H H B D B B +6 D6Mit150 51 116.105145 H H H B H H D D H H H H H H D H H B D B B H H H D B B H H H D D D H H H H B H D H B H B D H H D H D H H B D B B +6 D6Mit135 62.3 128.784911 H B B B H H D D H D H H H H H H H B D B B H B H D B B D H H H D H H H H H B H D B B H H D H H D H D B H B D B B +6 D6Mit374 63.7 134.069467 H B B B H H D D H D H H H H H H H B D B B H B H D B B D H H H D D H H H H B H D B B H H D H H D H D H H B D B B +6 D6Mit339 65 136.372096 H B B B H H D D H D H D H H H H H B D B B H B H D B B D H H H D D H H H H B H D B B H H D H H D H D B H B D B B +6 D6Mit201 74.1 146.582002 H B B B B H D D B H H D H H H H H B D B H H B H D B B D H H H D D H H H H B H D H B H H H H H D H D H H B H B B +7 D7Mit178 0 3.463879 H B B H H H D H H D B H D H H B H B B D H B D B H H H D H B H H D D H B D H H H B D D D B H D H H B H B D H H H +7 D7Mit190 2.9 17.644355 H B B H H D D D H D B H D H H B H B B D H H D B H H H H H B H H D D D B D H H H B D D D B H D H H H H H D H H H +7 D7Mit114 8.1 27.523162 H B B H H D D D H D B H D D H H H B B D H H D B H H H H B B B H D D H B D H B H H D D D B H D D H H H H H H H H +7 D7Mit80 18 47.494517 H B B H H H H H H D B H D D D H B H B D H H D B H B H H B B B D D D H B D D B H H D D D B H D D H H H H H H B D +7 D7Mit230 24.5 56.764848 B B B B H H H H B D B H D D D H B H B D H H D B H B H H B B B D D H H B D D B H H D D D H H D D H H H H H H B D +7 D7Mit84 28.4 66.454555 B B H B H H H H B D B H D D D H B H B D H H D B H B H H B B B D D H H B H D B H H D D D H H D D H H H H H H B D +7 D7Mit195 28.5 72.726203 B B H B H H H H B D B H D D D H B H B D H H D B H B H H B B B D D H H B H D B H H D D D H H D D H H H H H H B D +7 D7Mit202 37 83.020513 H B H B H H H H B D B H D H D H B H B H H H D H H B H H B B B H D H H B B H B H H D D D H H D D D H B H H H B H +7 D7Mit350 41 90.734598 H B H B H H H H B D B H D H D H B D B H H H D B H H H H B B B D D H H B B H B H H D D D H H D D D H B H H H B H +7 D7Mit301 46.5 98.73242 H B H B H H H H B D B H D H D H B D B H H H D B H H H H B B B D D H H B B H B B H H D D H H D D D H B H H H B H +7 D7Mit323 50 108.024449 H H H B H H H H B D B H D H D B B D B H H H D B H H H H H B B D D H H B B H B B H H D D H H D D D H B D H H B H +7 D7Mit281 52.4 119.355843 H H H B B H H H B D B H D H D B B D B H H H D B H H H H H B B D D H H B B H B B H H D D H H D D D H B H H D B H +7 D7Mit40 53 123.960955 H H H B B H H B B D B H D H D B B D B H H H D B H H H H H B B D D H H B B H B B H H D D H H D D D H B H H H B H +7 D7Mit66 57.5 127.029509 H H H B B H H B B D B H D H D B B D B H H H D B H H H H H B B D D H H B B H B B H H D D H H D D D H B H H H B H +7 D7Mit12 65.9 143.722526 H H H B B H H B H D B H D H D B H D B B H H D B H H H H D B B D D H H B B H H B H D B D H H H H H D B H D H H B +7 D7Mit334 69 145.481454 H H H B B H H B H H B H D H D B H D B B H H D B H H H H D B B D D H H B B H H B H D B D H H H H H D B H D H H B +7 D7Mit259 72 151.943408 H H H B B D H B H H H H D B D H H D B H H H D H H H H D D B D D D B H B B H H B H D B D H H H H D H B H D H D B +8 D8Mit124 6 14.723159 H H H D H H B H H H B B B D D H H H B H B H B D H B H D H H B D D H B D H D B H H H B H H B H D H H D B B H H D +8 D8Mit335 7 19.165365 H H H D H H B H H H B B B D H H H H B H H H H D H B H D H H B D D H B D H D B H H H B H H B H H H H D B B H H D +8 D8Mit95 8 25.604644 H H H D H H B H H H B B B D H H H H B H H H H D H B H D H H B D D H B D H H B H H H B H H B H H H H D B B H H D +8 D8Mit94 13 32.452129 H H H D H H B H H H B B B D H H H H B H H H H D H B H D H H B D D H B D D H B H H H H H H B H H H H D B B H H D +8 D8Mit294 22.5 40.490764 D H H D B H B H H H B B B H H H H H B B H H H D H B H D H H B D D H B D D H B H H H H H H B H H H H D B B H H D +8 D8Mit100 31 59.139595 D H H H B H H H B H H B H H H H H H B B H H H D H H H D H H B D D H B D D H B H H H H H H B H H H H D B B H H D +8 D8Mit25 32 67.115826 D H H H B H H H B H H B H H H H H H B B H H H H H H H D H H B D D H B D D H B H H H H H H B H H H H D B B H H D +8 D8Mit145 33.7 74.271358 D H H H B H H H B H H B H H H H H H B B H H H H H H H D H H H D D H B D D H B H H H H H H B H H H H D B B H H D +8 D8Mit263 37 83.834763 D D H H B H H H B H H H H B H H H H B B H H H H H D H D H H H D D D B D D H B H H H H H H B H H B H H B B H H D +8 D8Mit236 38.1 86.35109 D D H H B H H H B H H H H B H H H H B B H H H H H D H D H H H D D D B D D H B H H H H H H B H H B H H B B H H D +8 D8Mit266 44.5 92.726393 D D H H B H H H B H H H H B H H D H B B H H D H H D H D H B H D D D B D D H B D H H H H H B H H B B H B B H H D +8 D8Mit242 47.9 104.283476 D D H H B H H D B H H H H B H H D H B H H H D H H D H D H B H D D D B D D H B D H H H H H B H H B B H B B H B D +8 D8Mit113 52 111.364945 D D H H H H H D B H H H H B H H H H B H H H D H B D H D H B H D D D B H D B B D H D H H H B H H B B H B B B B D +8 D8Mit360 59 119.245087 D D H H H D H D H H H H H B H H H H B H H H H H B D H D H B H D D D B H D B B D H D H H H B H H B B B B B B H D +8 D8Mit156 74.3 131.419403 D D H H D D H H H H D H H B H H H H B H B D H H B D H D H B H D D D B H D H D D H D H D H H H B B B H D B B H D +9 D9Msw3 2 3 B D H H B D B H D B B H H B D H H D H H H H D D H H H B D B H H H H D H H D H H H B B H D D H H H H H D H H H H +9 D9Mit90 9 32.308039 B D H H H D B H H B B H H H H B H D H H D H H H H D B B D H B H H B D H H D H H H B B B D H D H B H H D H H H B +9 D9Mit227 23 41.298948 H D H H H D B H B B B H H D H B H D H H D H H H H D B B D H B H H B D H H D H H H B B B D B D H B H B D H H H B +9 D9Mit4 29 51.931282 H D H H H D H H B B B H H D H B H D D H D H H H H D B B D H B H H H D H H D H H H B B B D B D H B H B D H H H B +9 D9Mit336 35 65.42567 H D H H H D H H B B H H H D B B H D D H D H H H H H B B D H B H H H D B H H D H H B B B D B D H B H B B D H H B +9 D9Mit263 42 75.487998 H D D H D D H H B H H H H D B B H D D D D H H H D H B B D H B H H H H B H H D H D B H B D B D H B H B B D H H H +9 D9Mit236 43 79.938717 H D D H D D H H B H H H H D B B B D D D D H H H D H B H D H B H H H H B H H D H D B H B D B D H B H B B D H H H +9 D9Mit11 47 86.133451 H D D H D D H H B H H H B D B B B D D D D H H H D H B H H H H H H H H B H H D H D B H B D B D H B H B B D H H H +9 D9Mit274 49 96.298228 H D D H D H H H B H H H H H B H B D D D D H H H D H B H H H H H H H H B H H D H D B H B D B H H B H B B D H H H +9 D9Mit53 57 104.684611 D D D H D H H H B H H H H H B H B D D D D H H H D H B H H D D H H H H H H H D H D B H H D B H H B H B B D H H H +9 D9Mit243 61.8 113.283204 D D D H D H H H B H H H H H B H B D H D D H H H D H B H H D D B H H H H H H H H D B H D D B B H B H B B D H H H +9 D9Mit19 71 120.271886 D D D H D B H H H D H H H H B B B D B D D H D H D B B H B D D B H H H H H H H H D B H D H H B H H H B B D B H H +10 D10Mit28 4 9.133172 H H B H H D H H H B B H B H H H B H B B H D H D B D H B H B H B B H D H D H H B D H H D D B B B H H D D B D B D +10 D10Mit247 7 15.477118 H H B H H D H H H B B H B H H H B H B B H D H D B D H B H B H B B H D H D H H B D H H D D B B B H H D D B D B D +10 D10Msw20 12 20.063835 H H B H H D H H H B B H B H H H B H B B H D H D B D H B H B D B B H D H D H H B D H H D D B B B H H D D B D H D +10 D10Mit3 21 28.871991 H H B H H D H H H B B H B H H H B B H B H D H D H D B B H H D B B D D B D H B B D H B D D B B B H H D D B D H D +10 D10Mit194 29 46.564112 H H B H H D H H H B B H B H H H B B H B H H H D H D H H H H D B B D D B H H D B D H B D D B B H H H D D B D H D +10 D10Mit15 33 66.47519 H H B H H D H H H B B B H H H H B B H B H H H D D D H B H H D H H D D B H H D B D H B D H H H H H D D D B H H D +10 D10Mit186 40 75.143879 H H B H H H D H B B B B H H H H B B D B H H H D D D H B H H D H H D D B H H D B D H B D H H H H B D D D B H H D +10 D10Mit261 47 85.081862 H H B H B H D H B B B B H H H H B B D B H H H D D H H B H H D H H D D B H H D B D H B D H H H H B D D D B H H D +10 D10Mit11 50 91.885359 H H B H B H D H B B B B H H H H H H D B H H H D D H H B H H H H D D D B H H D B D B B D H H H H B D D D B H D D +10 D10Mit70 60 103.53585 H H B B B H D D B B B B H H H H H H D B H D H D D H H B H H H H D D D B H B D B D B B D H H H H B D H D B H H H +10 D10Mit233 62 113.818251 H H H B H H D H B B B B H H B H D H D B H D H D D H H B H H H H D D D B H B D H H B B D H H H H B D H H B H H H +10 D10Mit14 65 118.098314 H H H B H H D H B B B B H H B H D H D B H D H D H H H B H B B H D D D B H B H H H B B D H H H H B D H H B B H H +10 D10Mit297 70 124.484225 H H D B H H D H B B B B H H H H D H D B D D D D H H D B H B B H D H D B H B H H H B B D H H H H B D H B B B H H +11 D11Mit226 1 8.804957 H D B H D H H B B H H D D B H H D H H B H H H B D H H H B B H H D B B H D H B H H H H H H H D D H H B D H B B D +11 D11Mit78 3 17.844333 B D H H D H H H B H H D D B H H D H H B H H H B D H H H B B H H D H H H D H H H H H H H H H D D H H B D D B B D +11 D11Mit82 11 25.961779 B H H H D H H H B B H D D B H H D H H B H H H B H H H H B B H H D H H H D H H H H H H H H H D D H H B D D B B H +11 D11Mit51 18 36.205251 B H H H D H H H B H B D D B H H D H H B H H H B H H H H B B H H D D H H D H D B H D H H H H D D H H B D D H B H +11 D11Mit20 20 44.552712 B H H H D H H D B H B D D B H H H H D B H H H B H D H H B B H H D D H H D H D B H D H H H H D D H H B D D H B H +11 D11Mit86 28 54.003616 B H H H D H H D B H B H D B H H H H D B H H H B H D H H B B H H D D H H D H D B H D H H B H D D H H B D D H B H +11 D11Mit177 36 65.026386 B H H H D H B D B H B H H H H H B H D B H H B B B H H H B D H H H D H H H H D B H D H H B H D D H H H D D H H H +11 D11Mit30 40 69.607574 B H H H D H B D B H B H H H H H B H D B H H B B B H H H B D H H H D H H B H D B H D H H B H D D H H H D D H H H +11 D11Mit90 42 70.313263 B H H H D H B D B H B H H H H H B H D B H H B B B H H H B D H H H D H H B H D B H D H H B H D D H H H D D H H H +11 D11Mit195 47 84.653999 B H H H D H B D B H B H H H H H H H D B H H B B H H H H B D H H H D H H B H D B H D H H B H D H H H H D D H H H +11 D11Mit179 52 89.696612 B H D H D H B D B H B H H H H H B H D B H H B B H H H H B D B H H D H H B H D B H D D H B B D H H H H D D H H H +11 D11Mit263 55 95.602952 B H D H D D B D B H B H H H H H B B D B H H B B H H H H B D B H H D H H B H D B H D D H B B D H H D H D D B H H +11 D11Mit67 56 96.86818 B H D H D D B D B H B H H H H H B B D H H H B B H H H H B D B H H D H H B H D B H D D H B B D H H D H D D H H H +11 D11Mit199 62 101.749081 B H D H D D B D B D B H H H H H B B D H H H B B H H H H B D B H H D H H B H D B H D D H B B D H H D H D D H H H +11 D11Mit58 65 104.43775 B H D H D D B D B D B H H H H H B B D H H H B B H H H H B D B D H D H H B H D B H D D H B B D H H D H D D B H H +11 D11Mit181 66.5 109.189663 B H D H D D B D H D B H H H H H B B D H H B B B H H H H B D B D H D H H B H D B B D D H B B D H H D H D D B H H +11 D11Mit338 74.5 115.323096 H H D H D D B D H D H H H D D D B B D D H H H B H H H H H D B H H D H D B H D B B D D H B B D B H D H D D B H H +11 D11Mit48 77 117.993077 H H D H D D B D H D H H H D D D B B D D H H H B H H H H H D B H H D H D B H D B B D D H B B D B H D H D H B H H +12 D12Mit182 2 10.877408 H B H B H H H D H H B B H H H H H H H H H H B D H H H H H H D H H H B H B B H D H H D H H H B D H H B H B D D H +12 D12Mit219 7 27.125818 B B H B H H H D D H B B H H H D H H H H H H B D H H H H H H D H H H B H B B H D H H D H D H B D H H B H B D D H +12 D12Mit153 15 35.920168 H B H B H H H H D H B B H H H D H H H H H H B D H H H H H H D H H D B H B B H D H H D H D H B D H H B H B D D H +12 D12Mit2 19 42.747378 H B H H H H H H D H B B H H H D H H H H H H B D H H H H H H D H H D B H B B H D H H D H D H B D H H B B B D D D +12 D12Mit285 23 55.750111 B H H H B H H H D H B B H H H D H H H H H H B D H H H H H H D H H H B H B B H D H H D H D H B D H H B B B D B D +12 D12Mit36 23.5 61.756235 B H H H B H H H D H B B H H H D H H H H H H B D H H H H H H D H H H B H B B H D H H D H D H B D H H B B B H B D +12 D12Mit114 24.5 71.186214 B H H H B H D H D H H H H H H D H H H H H H B D H H H H H H D H H H B H B B H D H H D H D H B D B H B B B H B D +12 D12Mit158 38 83.720002 B H H H B H D H D H H H H H H D H H H B H H B D H H H H H H B H H H H H B B H D D H H H D H B H B H B B B H B D +12 D12Mit239 44 89.807378 B H H H B H D H D H H H H H H D H H H H H H B D H H H H H H B H H H H H B B H D D H H H D H B H B H B B B H B D +12 D12Mit259 45 93.085023 B H H H B H D H D H H D H H H D H H B H H H B D H H H H H H B B B H H H B B H D D H H H D H B H B H B B B H B D +12 D12Mit231 48 101.804025 B H H H B B D H D H H D H H D D H B B H H H B D H H D H H H B B B H H H B B H D D D H H D H B H B H B B B H B D +12 D12Mit133 56 111.536236 B H H H B B H H D H H D H H H D H B B H B H B H H D D H B H B H B H H B B B H D D D H H D H B B B H B B B H B D +12 D12Mit280 55 112.417854 B H H H B B H H D H H D H H H D H B B H B H B H H D D H B H B H B H H B B B H D D D H H D H B B B H B B B H B D +13 D13Mit57 9 17.085793 D B B B H B D B H D H B B D H B B H B H D H D H H D D D H H H B H H B B D D D H H H H B D H H H H H D H D H H H +13 D13Mit17 10 21.385134 D B B B H B D B H D H B B D H B B H B H D B D H H D D D H H H B H D B B D D D H H H H B D H H H H H D H D H H H +13 D13Mit60 16.1 35.968793 D B B B H B D B H D H B B D H B B H B H D B D H H D D D D H B B H H H B H D D H B H H H D H H H H H D H D H H D +13 D13Mit91 30 46.91822 D B H B H B D B H D H B H D H B B H B H D B D H H H D D D D B B H H H B D D D H B H H H D H H H D H D H D H H D +13 D13Mit13 35 56.582796 D B H B H B H H H D H B D D H B B H B H D B D D B H D D D D B B H H H B D H D H B H H H D H H H D H D H D H H D +13 D13Mit253 37 64.10121 D B H B H B H H H D H B D D H B B H B H D B D D H H H D D D B H H H H B H H D H B H H H D H H H D H D H D H H D +13 D13Mit254 40 76.121928 H B H B H B H H H D H B D D H B B H B H D B H D H H H D D D B B H H H B H H D H B H H H D H D H D D D H D H H D +13 D13Mit126 41 85.473356 H B H B H B H H H D H H D D H B B H B H D B H D H H H D D D B B H H H B H H D H B H B H D H D H D D D H D B B D +13 D13Mit193 43 91.92066 H B H B H B H H H D H H D H H B B H B H D B H D H H H D D D B B H H H B H H D H B H B H D H D H D D D H D B B D +13 D13MIt30 52 102.222838 H B H B H B H H H D H H D H H B B H B H D B H D H B H D D D B B H H H B H H D B B H B H D H D H D D H H D H B D +13 D13Mit148 59.5 109.618962 H B H B D B B H H D H H D H H B B H H H D B H D H B H D D H B B H H D H H H D B B H B D H H D H D D B H D H H D +13 D13Mit262 68 113.604437 H B H B D B B H H D H H D H H B B D H H D B H D H B H D D H H B H H D H H H D B B H B D B H D H D D B H D H H D +13 D13Mit35 75 120.12845 H H H B D B B H H D H H D H H B B D H H H B H D B B H D D H D B H H D H H H D B B H B D B H D H D D B H D H H D +14 D14Mit110 4 8.991951 H H H D B B H H H B D B H H H D B H D H H H B D B H H B B B H H D H H H H B D D H D D B H D B B B B B H D H D B +14 D14Mit98 4 17.356224 H B H D B B H H H B D B H H H D B H D H H H B D B H H B B B H H D H H H H B D D H D D B H D B B B B B H D H D B +14 D14Mit206 5 21.523025 H D H D B B H H H B D B H H H D B H D H H H B H B H H B B B H H D H H H H B D D H D D B H H B B B B B H D H D B +14 D14Mit54 12.5 36.137025 D D H D B H B H H B H B H H H D B H B H H H B H H B H B B B H H H H B H D B D D H D D B H H H B B B H H D H D B +14 D14Mit212 13 40.817103 D D H D B H B H D B H B B H H D B H B H H H B H H H H B B B H H H H B H D B D D H D D B H H H B B B H H D H D B +14 D14Mit142 19.4 54.812402 D D H D B H B H D B H B B H H D B H B H B D B H H H H B B B H H H H B H H B D H H H D B H H H H B H H H H H D B +14 D14Mit234 22.5 60.262795 D D H D B H H H D B H B B H H D B H B H B D B H H H H B B B H H H H H H H B D H H H D B H H H H B H H H H H D B +14 D14Mit262 28.5 67.704456 D D H D B H H H D B H B H H H D B H B H B D B H H H H B B B H H H H H H H B D H D H D B H H H H B H H H H H D B +14 D14Mit115 40 73.244747 H D H D B H H H D B H B H H B D B H B D B D B H H H B B B B H H H H H H H H D H D H D B H H H H B H H H H H D B +14 D14MIt35 43 79.559826 H D H D B H H H D B H B H H B D B H B D B D B H H H B B B B H H D H H H H H D H D H D B H H H H B H D H H H D B +14 D14Mit263 44 89.3607 H D H D B H H H D H H B H H B D B H B D B H B H H H B B B B H B D H B H H H D H D H D B H H H H B H D H H H D B +14 D14Mit228 46.7 99.784302 H D H D B H H B D H H B H H B D B H B D B H B H D H B B B B H B D H B H D H D H D H D B H H H H B H D H H H H B +14 D14Mit165 52.5 106.982673 H D H D B H H B D H B B H B B D B H B D B H B H D H B B B H H B D H B H D D D H D H H B H H H H B H D H H H H B +14 D14Mit185 54 117.296055 H D H H B B H B D H B B H B B D B H B D B H B H D H H H B H H B D H B H D D D H D H H B H H H H H H D B H H H B +14 D14Mit266 59 121.431466 H H H H B B H B D H B B H H B D H H H D B H H H D H H H B H H B D H B H D D D H D H H B D B H D H H D B H H H B +15 D15Mit12 6.4 3.160684 B H B B H H H H H D B H H H B D B B B B B D B B H D H D H H B H D D B D D B H D D H H D B B B B H H D H D H B B +15 D15Mit53 9.2 13.210209 H H B B H H H H H D B H H H B D B B B B H D B B H D H D H H B H H D B D D B H D H H H H B B B B H H D H D H B B +15 D15Mit252 13.2 22.550162 H H B B H H H H H D B H H H B D B B B B H H B B H D B D H H B H H D H D D H H D H H H H B B B B H H D H D H B B +15 D15Mit7 14.5 32.946234 H H B B H H H H H D B H H H B D B B B B H H B B H D B D H H B H H H H D D H H H H H H H B B B B H H D H D D B B +15 D15Mit8 14.6 33.392974 H H B B H H H H H D B H H H B D B B B B H H B B H D B D H H B H H H H D D H H H H H H H B B B B H H D H D D B B +15 D15Mit5 22.2 43.279929 H H B B H H H H H D B B H D B D B B B H H H B H H D B D H H B H H H H D D H H H H H H H B B B B H H D H D D B B +15 D15Mit232 24 52.944064 H H B B H H H H H H B B H D B D B B B H H H B H H D B D H H B H H H H D D H H H H H H H H B B H H H D H D D H B +15 D15Mit270 29 63.349351 H H H B H H H H H H B B H D B D B B B H H H B H H D B D H H B H H H H D D H B H B H H H H B B H H H D H H D H B +15 D15Mit90 36 68.969215 H B H H B H H H H H H B H D B D B B B H H H B H H D B D H H B H H H H D D H B H B H H H H B B H B H D B B D H H +15 D15Mit239 45 78.407334 H B H H H H H H H H H B H D B D B H B D H H H H H D B D H H B H H H H D D H B H B B H H H B B H B H D H B D H D +15 D15Mit72 51.1 84.545798 H B H H B H H H H H H B H D B D B H B D H H H H H D B D H H B D H H H D D H B H B B H H H B B H H H D H B D H D +15 D15Mit34 52.5 90.583805 H B H H B H H H H H D B H D B D B H B D H H H H D D B D H H B D B H H D D H B H B B H H H B H H H H D H B D H D +15 D15Mit272 57.5 94.239432 H B H D B H H H B H D B H D H H B H B D H H H H D D B D H H B D B H H D D H B H B B H H H H H H H H D H B D D D +15 D15Mit42 59.2 98.887015 H B D D B H H H H H D B H D D H D H B D H H H H D D B D H H B D B H H D D H B H B B B H D H H H H D D H B D D D +15 D15Mit15 62 102.823544 H B D D B H H H H H D B H D D H D H B D H H H H D D B D H H B D B H H D H H B H B B B H D H H H H D D H B D D D +15 D15Mit35 62 103.347763 H B D D B H H H H H D B H D D H D H B D H H H H D D B D H H B D B H H D H H B H B B B H D H H H H D D H B D D D +16 D16Mit182 3.1 5.682588 H H H B H H H B H H D H H H B H B H H H D B D D B B B H H H H B B B H H D H B D B H B H D D B B H B H H B H H H +16 D16Mit100 8.5 12.095264 D H H B H H H B H H D H H H B H B H H H D B H D B B B H H H H H B B H H D H B D H H B D D D B B H B H H B H H H +16 D16Mit88 9.7 13.249056 D H H B H H D B H H D H H H B H B H H H D B H D B B B H H H H H B B H H D H B D H H B D D D B B H H H H B H H H +16 D16Mit101 17 23.737061 D B H B H H D B H H D H H H B H B H H B D B H D B B B H H H H H B B H D D H B D H H B D H D B B H H H H B H H H +16 D16Mit58 23.3 32.312107 D B H H H H D B H H H H B H B H B H H B D B H D B H B H H H H H B B H D D H H D H H B D H D B B H H H H D H H H +16 D16Mit84 34.2 45.39781 D B H H H H D B B H H H B D B H H H H H D B B D B H B H H H H H B B H D D H H D H B B D H H H B H H D H D H H H +16 D16Mit5 38 57.773676 D B H H H H D B B H H H B D B H H H H H D B B D B H B D H H H H H B H D D H H D H B B D H H H B D H D H D H H H +16 D16Mit139 43 65.669761 D B H H H H H H B H H H B D B H H H H H H B B D B H B D H D H H D B H D D H H D H B B D H H H B D H D H D H H H +16 D16Mit217 45.5 77.361452 D B H H H H H H B H H H B D B H H H H H H H B D B H B D H D H H D H H D D D D D H B H D H H H B D H D H D H D H +16 D16Mit152 57 85.804078 D B H H H H H H B H H H H D B H H H H H H H B D B H B D H D H H D H H D D D D D H B H D H H H B D H D H D H D H +16 D16Mit106 68 98.051756 H B D H H H H H H D H D H D B B H D D H B B B H H H H D H D D H D H H D H D D D H B H D H H D B D H D H D D D H +17 D17Mit267 2 3.354861 B D D H D D B D H H D H B H B H H H H D D D B D H B D D H B B H D H H B H D B B D B H H D H B H H H H D D D D H +17 D17Mit213 9.33 16.752156 B D D H D D B D H D D H B H H H H H H D D D H D H B D D H B B H D H H B H D B B D H H H D H B B H H H D D D D H +17 D17Mit100 11.8 26.318982 B D D H D D B D H D D H B H H H H H H D D D H D H B D D H B B H D H H B H D B B D H H H D H B B H H H D D D D H +17 D17Mit175 17.7 31.979622 H D D D D D B D H D H D H H H H H H H D D D H D H H H D D B B H D H H B H D B H D H H H D H B B H H H D H D H H +17 D17Mit21 18.6 34.380178 H D D D D D B D H D H D H H H H H H H D D D H D H H H D D B B H D H H B H D B H D H H H D H B B H H H D H D H H +17 D17Mit24 20.4 37.619108 H D D D D D B D H D H D H H H H H H H D D D H D H H H D D B B H D H H B H D B H D H H H D H B B H H H D H D H H +17 D17Mit10 24 47.672121 H D D D D D B D B D H D H H H H H H H D D D H H H H H D D H B H H H H B H D B B D H H H D B B B H H H D H D B H +17 D17Mit20 34.3 57.366869 H D D D D H B H B D H D H H H H H H H D D H H B H H H D D H B B H H H B H D B B D H H D D B B B H H H H H H B H +17 D17Mit89 36 63.988383 H D D D D H B H B D H D H H H H H H H D D H H B H H H D D H B B H H H B H D B B D H H D D B B B H H H H H H B H +17 D17Mit152 37.7 65.689823 H D D D D H B H B D H D H H H H H H H D D H H B H H H D D H B B H H H B H D B B D H H D D B B B H H H H H H B H +17 D17Mit39 45 74.681455 H H D D H H B H B D H D D H H H H H H D D H H B H H B B D H B B H H B B H D H B D H D D D H H H H H H H H H B H +17 D17Mit41 53 84.734942 H H D D H H B H B D H D D H D H D H H D D H D B D H B B D H H H H H B B H H H B H H D D D H H H D H H H H H B H +17 D17Mit221 56.7 90.487044 H H D H H H B H H D H D D H D H D H H D D B D B D H B B D H H H B H B B H H H B H H D D H H H H D H H B D H B H +17 D17Mit244 55.7 91.253863 H H D H B H B H B D H D D H D H D H H D H B D B D H B B D H H H B H B B H B H B H H D D H H H H D B H B D H B H +18 D18Mit19 1 5.041116 B B B B H B H H B H B D D D B H H H B D D H B D H B H H D B H B D B B D B D H D H H H D H D H H D B H H H H B H +18 D18Msw9 3 9.164794 B B B B H B H H B H B D D D B H H H B D D H B D H B H H D B H B D B B D H D H D H H H D H D H H D B H H H H H H +18 D18Msw17 10 17.128182 B B B B H B H H H B B D D D B H H H H D H H B D H B H H D B H B D B B D B D H D H B H D H H H H D B H H H H B H +18 D18Mit68 11 21.594125 B B B B H B H H H B B D D D B H H H H D H H B D H B H H D H H B D B B D B D H D H B H D H H H H D B H H H H B D +18 D18Mit111 11 21.671805 B B B B H B H H H B B D D D B H H H H D H H B D H B H H D H H B D B B D B D H D H B H D H H H H D B H H H H B D +18 D18Mit225 16 30.775424 H B H B H H H H H H B H D D B H H H H H H H B D H B H H D H H B H B B D B D H D H B H D H H H H D B B H H H B D +18 D18Mit17 22 39.646514 H B H B H H H H H H B H D D B H H H H H H H B H H B H H D D H B H B B D B D H D H B H D B H H H D B B H H H B D +18 D18Mit53 27 52.992737 H B H B H H H H H H B B D D B H H H H H H H B H H H H H D D H B H B H D B D D D H B H H B H H H D B B H H H B D +18 D18Mit55 25 53.317603 H B H B H H H H H H B B D D B H H H H H H H B H H H H H D D H B H B H D B D D D H B H H B H H H D B B H H H B D +18 D18Mit184 41 66.978896 H B H B H H B H H H B B D D H H B B H H H H B B H H H H D D H B H B H D B D D D H B H H H H H H D B H B H H B D +18 D18Mit79 47 75.969567 H B H B H H B H H H B B D D H H B H B H B H B B H D D H D D B B H B H D B D D D D B H H H H H D D B H B H H B D +18 D18Mit7 49 77.086364 H B D B H H B H H H B B D D H H B H B H B H B B H D D H D D H B H B H H B D D H D B H H H H H D D B H B H H B D +18 D18Mit213 55 84.78992 H B D B H H B H H H H B D H H H B H B H B H B B H D D B D D H B B B D B B D D H D B H H H H H H D B H B D B B D +19 D19Mit109 3 6.207606 H H B H H H H H H H H D D B B D B H B H B H D B H H H H H H H D D H H D B B H D H H H H H H H H H H H H D B H B +19 D19Mit42 5 10.157494 H H B H H H H H H H H D D B B D B H B H B H D B H H H H H H H D D H H D B H H D H H H H H H H H H H H H D B H H +19 D19Mit85 12 18.60417 D H B H H B H H H H H D D B B D B B B H B H D B H H D H H H H D D H H H B H B D D D B H H H D H H B H H H B H D +19 D19Mit16 15 20.420341 D H B H H B H H H H H D D B B D B B B H B H D B H H D H H H H D D H H H B H B D D D B H H H D H H B H H H B H D +19 D19Mit13 20 32.713512 D H B B H B H B H H H H D B B D B B B H B H D B B H D D H B H D D H D B B H B D D D B H H H D D H B H H H D H D +19 D19Mit89 41 42.573794 D H B B H B H B B H H H H B H D B B B H B H D B H H D D H B H D D H D B B H B D D D B H H H D D H H H H H D H D +19 D19Mit38 47 47.260672 D H B B H B H H B H H H H B H D B B B H B H D B H H D H H B H D D H D B B H B D D D B H H H D D H H H H H D H D +19 D19Mit103 52 53.838655 D D H B H B H H H H H H H H H D B B B H B H D B H H D H H B H H D H D B B H B D D D B H H H D D H H H H D D H D +19 D19Mit55 52.8 55.379504 D D D B H B H H H H H H H H D D B B B H B H D B H D D H H B H H D H D B B H B D D D B H H H D D H H H H D D H D +19 D19Mit137 54 59.209811 D D D B H B D H H H H H H H D D B B B H H B D B H D H H H H H H D H D B B H B D D D B H H H D D H H H H D D H D +X DXMit89 3 9.977111 D H B D H D D B D D B D D B D B H D H B D B B D D B D B D D D D H B D B H H B B D B H B B D H B B B B B D D D D +X DXMit166 15.5 49.036674 D H B D H D D H D D B D D B D B H H H D D B B D D B D D D D D D H B D B H H B B D D H B B D H B B D B B D B D D +X DXMit143 26 69.642046 D H B D H D D D D D B D D B D D H H H D D B B D D B D D B D D D B B H B H D B B D D H B B D H B B D B B D B H D +X DXMit1 29 70.273782 D H B D H D D H D D B D D B D D H H H D D B B D D D D D B D D D B B H B H D B B D D H B B D H B B D B B D B H D +X DXMit117 50.8 127.822561 D H B H D D D H D D B D D B D D H H H D D B B D B D D B B D H D B B H B H D B B D D D D B D H B B D D B B B H D +X DXMsw125 52 140.351087 D H D H D D D H D D B D D B D D H H H D D B D D B D D B B D D D B B H B B D B B D D D D B H H B D D D B B B H H +X DXMit186 69 161.804093 D H D H D D D H D D B D D B D D H H H D D B D D B D D B B D D D B B H B B H B B D D D D B H H B D D D B B B D H diff --git a/wqflask/base/data_set.py b/wqflask/base/data_set.py index 8965e1d1..489bd374 100755 --- a/wqflask/base/data_set.py +++ b/wqflask/base/data_set.py @@ -79,7 +79,7 @@ class Dataset_Types(object): def __init__(self): self.datasets = {} - file_name = "/home/zas1024/gene/wqflask/wqflask/static/new/javascript/dataset_menu_structure.json" + file_name = "wqflask/static/new/javascript/dataset_menu_structure.json" with open(file_name, 'r') as fh: data = json.load(fh) diff --git a/wqflask/wqflask/do_search.py b/wqflask/wqflask/do_search.py index 31dc11b5..921a4a47 100755 --- a/wqflask/wqflask/do_search.py +++ b/wqflask/wqflask/do_search.py @@ -382,11 +382,20 @@ class RifSearch(MrnaAssaySearch): DoSearch.search_types['RIF'] = "RifSearch" - def run(self): + def get_where_clause(self): where_clause = """( %s.symbol = GeneRIF_BASIC.symbol and MATCH (GeneRIF_BASIC.comment) AGAINST ('+%s' IN BOOLEAN MODE)) """ % (self.dataset.type, self.search_term[0]) + return where_clause + + def run(self): + #where_clause = """( %s.symbol = GeneRIF_BASIC.symbol and + # MATCH (GeneRIF_BASIC.comment) + # AGAINST ('+%s' IN BOOLEAN MODE)) """ % (self.dataset.type, self.search_term[0]) + + where_clause = self.get_where_clause() + from_clause = ", GeneRIF_BASIC " query = self.compile_final_query(from_clause, where_clause) diff --git a/wqflask/wqflask/marker_regression/marker_regression.py b/wqflask/wqflask/marker_regression/marker_regression.py index fa680f5f..60bc721e 100755 --- a/wqflask/wqflask/marker_regression/marker_regression.py +++ b/wqflask/wqflask/marker_regression/marker_regression.py @@ -13,7 +13,7 @@ import os import collections import uuid -import rpy2.robjects as robjects +import rpy2.robjects as ro import numpy as np from scipy import linalg @@ -79,7 +79,7 @@ class MarkerRegression(object): self.num_perm = start_vars['num_perm'] self.control = start_vars['control_marker'] - print("doing rqtl_geno") + print("DOING RQTL GENO") qtl_results = self.run_rqtl_geno() print("qtl_results:", qtl_results) elif self.mapping_method == "plink": @@ -88,8 +88,9 @@ class MarkerRegression(object): elif self.mapping_method == "pylmm": print("RUNNING PYLMM") self.num_perm = start_vars['num_perm'] - if int(self.num_perm) > 0: - self.run_permutations(str(temp_uuid)) + if self.num_perm != "": + if int(self.num_perm) > 0: + self.run_permutations(str(temp_uuid)) qtl_results = self.gen_data(str(temp_uuid)) else: print("RUNNING NOTHING") @@ -227,27 +228,104 @@ class MarkerRegression(object): os.system(rqtl_command) count, p_values = self.parse_rqtl_output(plink_output_filename) + + def geno_to_rqtl_function(self): # TODO: Need to figure out why some genofiles have the wrong format and don't convert properly + print("Adding a function to the R environment") + ro.r(""" + getGenoCode <- function(header, name = 'unk'){ + mat = which(unlist(lapply(header,function(x){ length(grep(paste('@',name,sep=''), x)) })) == 1) + return(strsplit(header[mat],'')[[1]][6]) + } + + GENOtoCSVR <- function(genotypes = 'BXD.geno', out = 'cross.csvr', phenotype = NULL, sex = NULL, verbose = FALSE){ + header = readLines(genotypes, 40) + toskip = which(unlist(lapply(header, function(x){ length(grep("Chr\t", x)) })) == 1)-1 # Major hack to skip the geno headers + genocodes <- c(getGenoCode(header, 'mat'), getGenoCode(header, 'het'), getGenoCode(header, 'pat')) # Get the genotype codes + + genodata <- read.csv(genotypes, sep='\t', skip=toskip, header=TRUE, na.strings=getGenoCode(header,'unk'), colClasses='character', comment.char = '#') + cat('Genodata:', toskip, " ", dim(genodata), '\n') + if(is.null(phenotype)) phenotype <- runif((ncol(genodata)-4)) # If there isn't a phenotype, generate a random one + if(is.null(sex)) sex <- rep('m', (ncol(genodata)-4)) # If there isn't a sex phenotype, treat all as males + outCSVR <- rbind(c('Pheno', '', '', phenotype), # Phenotype + c('sex', '', '', sex), # Sex phenotype for the mice + cbind(genodata[,c('Locus','Chr', 'cM')], genodata[, 5:ncol(genodata)])) # Genotypes + write.table(outCSVR, file = out, row.names=FALSE, col.names=FALSE,quote=FALSE, sep=',') # Save it to a file + require(qtl) + return(read.cross(file=out, 'csvr', genotypes=genocodes)) # Load it using R/qtl read.cross + } + """) def run_rqtl_geno(self): - robjects.packages.importr("qtl") - robjects.r('the_cross <- read.cross(format="csvr", dir="/home/zas1024/PLINK2RQTL/test", file="BXD.csvr")') + print("Calling R/qtl from python") + + self.geno_to_rqtl_function() + + ## Get pointers to some common R functions + r_library = ro.r["library"] # Map the library function + r_c = ro.r["c"] # Map the c function + + print(r_library("qtl")) # Load R/qtl + + ## Get pointers to some R/qtl functions + scanone = ro.r["scanone"] # Map the scanone function + calc_genoprob = ro.r["calc.genoprob"] # Map the calc.genoprob function + read_cross = ro.r["read.cross"] # Map the read.cross function + write_cross = ro.r["write.cross"] # Map the write.cross function + GENOtoCSVR = ro.r["GENOtoCSVR"] # Map the GENOtoCSVR function + + genofilelocation = webqtlConfig.HTMLPATH + "genotypes/" + self.dataset.group.name + ".geno" + crossfilelocation = webqtlConfig.HTMLPATH + "genotypes/" + self.dataset.group.name + ".cross" + + print("Conversion of geno to cross at location:", genofilelocation, " to ", crossfilelocation) + + cross_object = GENOtoCSVR(genofilelocation, crossfilelocation) # TODO: Add the SEX if that is available + if self.manhattan_plot: - robjects.r('the_cross <- calc.genoprob(the_cross)') + cross_object = calc_genoprob(cross_object) else: - robjects.r('the_cross <- calc.genoprob(the_cross, step=1, stepwidth="max")') + cross_object = calc_genoprob(cross_object, step=1, stepwidth="max") + + cross_object = self.add_phenotype(cross_object, self.sanitize_rqtl_phenotype()) # Add the phenotype + + # for debug: write_cross(cross_object, "csvr", "test.csvr") + + # Scan for QTLs + if(self.control.replace(" ", "") != ""): + covar = self.create_covariates(cross_object) + result_data_frame = scanone(cross_object, pheno = "the_pheno", addcovar = covar) + else: + result_data_frame = scanone(cross_object, pheno = "the_pheno") + + if int(self.num_perm) > 0: # Do permutation (if requested by user) + if(self.control.replace(" ", "") != ""): + covar = self.create_covariates(cross_object) + perm_data_frame = scanone(cross_object, pheno_col = "the_pheno", addcovar = covar, n_perm=int(self.num_perm)) + else: + perm_data_frame = scanone(cross_object, pheno_col = "the_pheno", n_perm=int(self.num_perm)) + + self.process_rqtl_perm_results(perm_data_frame) # Functions that sets the thresholds for the webinterface + + return self.process_rqtl_results(result_data_frame) + + def add_phenotype(self, cross, pheno_as_string): + ro.globalenv["the_cross"] = cross + ro.r('the_cross$pheno <- cbind(pull.pheno(the_cross), the_pheno = '+ pheno_as_string +')') + return ro.r["the_cross"] + + def create_covariates(self, cross): + ro.globalenv["the_cross"] = cross + ro.r('genotypes <- pull.geno(the_cross)') # Get the genotype matrix + userinputS = self.control.replace(" ", "").split(",") # TODO sanitize user input, Never Ever trust a user + covariate_names = ', '.join('"{0}"'.format(w) for w in userinputS) + print("Marker names of selected covariates:", covariate_names) + ro.r('covariates <- genotypes[,c(' + covariate_names + ')]') # Get the covariate matrix by using the marker name as index to the genotype file + print("R/qtl matrix of covariates:", ro.r["covariates"]) + return ro.r["covariates"] + + def sanitize_rqtl_phenotype(self): pheno_as_string = "c(" - #for i, val in enumerate(self.vals): - # if val == "x": - # new_val == "NULL" - # else: - # new_val = val - # if i < (len(self.vals) - 1): - # pheno_as_string += str(new_val) + "," - # else: pheno_as_string += str(new_val) - null_pos = [] for i, val in enumerate(self.vals): if val == "x": - null_pos.append(i) if i < (len(self.vals) - 1): pheno_as_string += "NA," else: @@ -257,107 +335,37 @@ class MarkerRegression(object): pheno_as_string += str(val) + "," else: pheno_as_string += str(val) - pheno_as_string += ")" - - robjects.r('the_cross$pheno <- cbind(pull.pheno(the_cross), the_pheno = '+ pheno_as_string +')') - - print("self.control:", self.control) - - if self.control != "": - control_markers = self.control.split(",") - control_string = "" - for i, control in enumerate(control_markers): - control_trait = GeneralTrait(name=str(control), dataset_name=str(self.dataset.group.name + "Geno")) - control_vals = [] - for sample in self.dataset.group.samplelist: - if sample in control_trait.data: - control_vals.append(control_trait.data[sample].value) - else: - control_vals.append("x") - print("control_vals:", control_vals) - control_as_string = "c(" - for j, val2 in enumerate(control_vals): - if val2 == "x": - if j < (len(control_vals) - 1): - control_as_string += "NA," - else: - control_as_string += "NA" - else: - if j < (len(control_vals) - 1): - control_as_string += str(val2) + "," - else: - control_as_string += str(val2) - #if i < (len(control_vals) - 1): - # control_as_string += str(new_val2) + "," - #else: - # control_as_string += str(new_val2) - control_as_string += ")" - print("control_as_string:", control_as_string) - if i < (len(control_markers)-1): - control_string += control_as_string + "," - else: - control_string += control_as_string - - robjects.r('covariates <- cbind( '+ control_string +')') - - r_string = 'scanone(the_cross, pheno.col="the_pheno", n.cluster=16, n.perm='+self.num_perm+', addcovar=covariates, intcovar=covariates[,'+ str(len(control_markers)) +'])' - print("r_string:", r_string) - - if int(self.num_perm) > 0: - thresholds = robjects.r(r_string) - self.suggestive, self.significant = self.process_rqtl_perm_results(thresholds) - r_string = 'scanone(the_cross, pheno.col="the_pheno", n.cluster=16, addcovar=covariates, intcovar=covariates[,'+ str(len(control_markers)) +'])' - - #r_string = 'scanone(the_cross, pheno.col='+pheno_as_string+', addcovar='+control_as_string+')' - - else: - #r_string = 'scanone(the_cross, pheno.col='+pheno_as_string+', n.perm='+self.num_perm+')' - r_string = 'scanone(the_cross, pheno.col="the_pheno", n.cluster=16, n.perm='+self.num_perm+')' - if self.num_perm.isdigit() and int(self.num_perm) > 0: - results = robjects.r(r_string) - self.suggestive, self.significant = self.process_rqtl_perm_results(results) - r_string = 'scanone(the_cross, pheno.col="the_pheno", n.cluster=16)' - - print("r_string:", r_string) - result_data_frame = robjects.r(r_string) - #print("results:", result_data_frame) + return pheno_as_string - qtl_results = self.process_rqtl_results(result_data_frame) - - return qtl_results - - def process_rqtl_perm_results(self, results): - - perm_vals = [] - for line in str(results).split("\n")[1:(int(self.num_perm)+1)]: - print("line:", line.split()) - perm_vals.append(float(line.split()[1])) - - self.suggestive = np.percentile(np.array(perm_vals), 67) - self.significant = np.percentile(np.array(perm_vals), 95) - - return self.suggestive, self.significant - - - def process_rqtl_results(self, result): + def process_rqtl_results(self, result): # TODO: how to make this a one liner and not copy the stuff in a loop qtl_results = [] - + output = [tuple([result[j][i] for j in range(result.ncol)]) for i in range(result.nrow)] - print("output", output) - - + print("R/qtl scanone output:", output) + for i, line in enumerate(result.iter_row()): marker = {} marker['name'] = result.rownames[i] marker['chr'] = output[i][0] marker['Mb'] = output[i][1] marker['lod_score'] = output[i][2] - qtl_results.append(marker) - + return qtl_results + def process_rqtl_perm_results(self, results): + perm_vals = [] + for line in str(results).split("\n")[1:(int(self.num_perm)+1)]: + print("R/qtl permutation line:", line.split()) + perm_vals.append(float(line.split()[1])) + + self.suggestive = np.percentile(np.array(perm_vals), 67) + self.significant = np.percentile(np.array(perm_vals), 95) + + return self.suggestive, self.significant + + def run_plink(self): os.chdir("/home/zas1024/plink") @@ -394,8 +402,8 @@ class MarkerRegression(object): self.dataset.group.markers.add_pvalues(p_values) return self.dataset.group.markers.markers - - + + def gen_pheno_txt_file_plink(self, pheno_filename = ''): ped_sample_list = self.get_samples_from_ped_file() output_file = open("%s%s.txt" % (webqtlConfig.TMPDIR, pheno_filename), "wb") diff --git a/wqflask/wqflask/my_pylmm/pyLMM/lmm.py b/wqflask/wqflask/my_pylmm/pyLMM/lmm.py index 5aa27106..1383d3fc 100644 --- a/wqflask/wqflask/my_pylmm/pyLMM/lmm.py +++ b/wqflask/wqflask/my_pylmm/pyLMM/lmm.py @@ -745,12 +745,11 @@ def gn2_redis(key,species): tempdata = temp_data.TempData(params['temp_uuid']) - print('kinship', np.array(params['kinship_matrix'])) + print('pheno', np.array(params['pheno_vector'])) - geno = np.array(params['genotype_matrix']) - print('geno', geno.shape, geno) if species == "human" : + print('kinship', np.array(params['kinship_matrix'])) ps, ts = run_human(pheno_vector = np.array(params['pheno_vector']), covariate_matrix = np.array(params['covariate_matrix']), plink_input_file = params['input_file_name'], @@ -758,6 +757,9 @@ def gn2_redis(key,species): refit = params['refit'], tempdata = tempdata) else: + geno = np.array(params['genotype_matrix']) + print('geno', geno.shape, geno) + ps, ts = run_other(pheno_vector = np.array(params['pheno_vector']), genotype_matrix = geno, restricted_max_likelihood = params['restricted_max_likelihood'], diff --git a/wqflask/wqflask/static/new/css/scatter-matrix.css b/wqflask/wqflask/static/new/css/scatter-matrix.css new file mode 100644 index 00000000..147903be --- /dev/null +++ b/wqflask/wqflask/static/new/css/scatter-matrix.css @@ -0,0 +1,40 @@ +#scatter-matrix { font-size: 14px; } + +.axis { shape-rendering: crispEdges; } +.axis line { stroke: #ddd; stroke-width: 1px; } +.axis path { display: none; } +.axis text { font-size: 0.8em; } + +rect.extent { fill: #000; fill-opacity: .125; stroke: #fff; } +rect.frame { fill: #fff; fill-opacity: .7; stroke: #aaa; } + +circle { fill: #ccc; fill-opacity: .5; } + +.legend circle { fill-opacity: 1; } +.legend text { font-size: 18px; font-style: oblique; } + +.cell text { pointer-events: none; } + +.color-0 { fill: #800; } +.color-1 { fill: #080; } +.color-2 { fill: #008; } +.color-3 { fill: #440; } +.color-4 { fill: #044; } +.color-5 { fill: #404; } +.color-6 { fill: #400; } +.color-7 { fill: #040; } +.color-8 { fill: #004; } +.color-9 { fill: #cc0; } +.color-10 { fill: #0cc; } +.color-11 { fill: #c0c; } +.color-12 { fill: #880; } +.color-13 { fill: #088; } +.color-14 { fill: #808; } +.color-15 { fill: #c00; } +.color-16 { fill: #0c0; } +.color-17 { fill: #00c; } + +.scatter-matrix-filter-control ul { list-style: none; padding-left: 10px; } +.scatter-matrix-variable-control ul { list-style: none; padding-left: 10px; } +.scatter-matrix-drill-control ul { list-style: none; padding-left: 10px; } + diff --git a/wqflask/wqflask/static/new/javascript/scatter-matrix.js b/wqflask/wqflask/static/new/javascript/scatter-matrix.js index 38cdc75b..15385b00 100644 --- a/wqflask/wqflask/static/new/javascript/scatter-matrix.js +++ b/wqflask/wqflask/static/new/javascript/scatter-matrix.js @@ -57,7 +57,7 @@ ScatterMatrix.prototype.render = function () { .attr('class', 'scatter-matrix-container'); var control = container.append('div') .attr('class', 'scatter-matrix-control') - .style({'float':'left'}) + .style({'float':'left', 'margin-right':'50px'}) var svg = container.append('div') .attr('class', 'scatter-matrix-svg') .style({'float':'right'}) diff --git a/wqflask/wqflask/static/packages/bootstrap/fonts/glyphicons-halflings-regular.eot b/wqflask/wqflask/static/packages/bootstrap/fonts/glyphicons-halflings-regular.eot new file mode 100644 index 00000000..4a4ca865 --- /dev/null +++ b/wqflask/wqflask/static/packages/bootstrap/fonts/glyphicons-halflings-regular.eot Binary files differdiff --git a/wqflask/wqflask/static/packages/bootstrap/fonts/glyphicons-halflings-regular.svg b/wqflask/wqflask/static/packages/bootstrap/fonts/glyphicons-halflings-regular.svg new file mode 100644 index 00000000..25691af8 --- /dev/null +++ b/wqflask/wqflask/static/packages/bootstrap/fonts/glyphicons-halflings-regular.svg @@ -0,0 +1,229 @@ +<?xml version="1.0" standalone="no"?> +<!DOCTYPE svg PUBLIC "-//W3C//DTD SVG 1.1//EN" "http://www.w3.org/Graphics/SVG/1.1/DTD/svg11.dtd" > +<svg xmlns="http://www.w3.org/2000/svg"> 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