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-rw-r--r--api_readme.md72
1 files changed, 56 insertions, 16 deletions
diff --git a/api_readme.md b/api_readme.md
index eef0b2d7..00ba25d7 100644
--- a/api_readme.md
+++ b/api_readme.md
@@ -1,25 +1,11 @@
-# API Command Documentation #
+# API Query Documentation #
## Fetch Species List ##
To get a list of species with data available in GN (and their associated names and ids):
```
curl http://gn2-zach.genenetwork.org/api/v_pre1/species
-[
- {
- "FullName": "Mus musculus",
- "Id": 1,
- "Name": "mouse",
- "TaxonomyId": 10090
- },
- ...
- {
- "FullName": "Populus trichocarpa",
- "Id": 10,
- "Name": "poplar",
- "TaxonomyId": 3689
- }
-]
+[ { "FullName": "Mus musculus", "Id": 1, "Name": "mouse", "TaxonomyId": 10090 }, ... { "FullName": "Populus trichocarpa", "Id": 10, "Name": "poplar", "TaxonomyId": 3689 } ]
```
Or to get a single species info:
@@ -57,6 +43,60 @@ curl http://gn2-zach.genenetwork.org/api/v_pre1/datasets/mouse/bxd
```
(I added the option to specify species just in case we end up with the same group name across multiple species at some point, though it's currently unnecessary)
+## Fetch Individual Dataset Info ##
+### For mRNA Assay/"ProbeSet" ###
+```
+curl http://gn2-zach.genenetwork.org/api/v_pre1/dataset/HC_M2_0606_P
+```
+OR
+```
+curl http://gn2-zach.genenetwork.org/api/v_pre1/dataset/bxd/HC_M2_0606_P```
+{ "confidential": 0, "data_scale": "log2", "dataset_type": "mRNA expression", "full_name": "Hippocampus Consortium M430v2 (Jun06) PDNN", "id": 112, "name": "HC_M2_0606_P", "public": 2, "short_name": "Hippocampus M430v2 BXD 06/06 PDNN", "tissue": "Hippocampus mRNA", "tissue_id": 9 }
+```
+(This also has the option to specify group/riset)
+### For "Phenotypes" (basically non-mRNA Expression; stuff like weight, sex, etc) ###
+For these traits, the query fetches publication info and takes the group and phenotype 'ID' as input. For example:
+```
+curl http://gn2-zach.genenetwork.org/api/v_pre1/dataset/bxd/10001
+{ "dataset_type": "phenotype", "description": "Central nervous system, morphology: Cerebellum weight, whole, bilateral in adults of both sexes [mg]", "id": 10001, "name": "CBLWT2", "pubmed_id": 11438585, "title": "Genetic control of the mouse cerebellum: identification of quantitative trait loci modulating size and architecture", "year": "2001" }
+```
+## Fetch Sample Data for Single Trait ##
+```
+curl http://gn2-zach.genenetwork.org/api/v_pre1/sample_data/HC_M2_0606_P/1436869_at
+[ { "data_id": 23415463, "sample_name": "129S1/SvImJ", "sample_name_2": "129S1/SvImJ", "se": 0.123, "value": 8.201 }, { "data_id": 23415463, "sample_name": "A/J", "sample_name_2": "A/J", "se": 0.046, "value": 8.413 }, { "data_id": 23415463, "sample_name": "AKR/J", "sample_name_2": "AKR/J", "se": 0.134, "value": 8.856 }, ... ]
+```
+
+## Fetch Trait Info (Name, Description, Location, etc) ##
+### For mRNA Expression/"ProbeSet" ###
+```
+curl http://gn2-zach.genenetwork.org/api/v_pre1/trait/HC_M2_0606_P/1436869_at
+{ "additive": -0.214087568058076, "alias": "HHG1; HLP3; HPE3; SMMCI; Dsh; Hhg1", "chr": "5", "description": "sonic hedgehog (hedgehog)", "id": 99602, "locus": "rs8253327", "lrs": 12.7711275309832, "mb": 28.457155, "mean": 9.27909090909091, "name": "1436869_at", "p_value": 0.306, "se": null, "symbol": "Shh" }
+```
+
+### For "Phenotypes" ###
+For phenotypes this just gets the max LRS, its location, and additive effect (as calculated by qtlreaper)
+
+Since each group/riset only has one phenotype "dataset", this query takes either the group/riset name or the group/riset name + "Publish" (for example "BXDPublish", which is the dataset name in the DB) as input
+```
+curl http://gn2-zach.genenetwork.org/api/v_pre1/trait/BXD/10001
+{ "additive": 2.39444435069444, "id": 4, "locus": "rs48756159", "lrs": 13.4974911471087 }
+```
+
+## Calculate Correlation ##
+Currently only Pearson Sample and Tissue correlations are implemented
+
+This query currently takes the following parameters (though more will be added):
+* trait_id (*required*) - ID for trait used for correlation
+* db (*required*) - DB name for the trait above (this is the Short_Abbreviation listed when you query for datasets)
+* target_db (*required*) - Target DB name to be correlated against
+* type - Sample or Tissue (default = Sample)
+* return - Number of results to return (default = 500)
+
+Example query:
+```
+curl http://gn2-zach.genenetwork.org/api/v_pre1/correlation?trait_id=1427571_at&db=HC_M2_0606_P&target_db=BXDPublish&type=sample&return_count=100
+[ { "#_strains": 6, "p_value": 0.004804664723032055, "sample_r": -0.942857142857143, "trait": 20511 }, { "#_strains": 6, "p_value": 0.004804664723032055, "sample_r": -0.942857142857143, "trait": 20724 }, { "#_strains": 12, "p_value": 1.8288943424888848e-05, "sample_r": -0.9233615170820528, "trait": 13536 }, { "#_strains": 7, "p_value": 0.006807187408935392, "sample_r": 0.8928571428571429, "trait": 10157 }, { "#_strains": 7, "p_value": 0.006807187408935392, "sample_r": -0.8928571428571429, "trait": 20392 }, ... ]
+```